Pharmaco-proteomic study of hydroxyurea-induced modifications in the sickle red blood cell membrane proteome

Experimental Biology and Medicine

Volumn 233, Issue 12, 2008, Pages 1510-1517

  Ghatpande, Swati S ^a   Choudhary, Pankaj K ^a   Quinn, Charles T ^a   Goodman, Steven R ^a,b  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b Medical University   (United States)

Author keywords

2D DIGE; Catalase; Hydroxyurea; Mass spectrometry; Red blood cell; Sickle cell disease

Indexed keywords

ANTIOXIDANT; BILIVERDIN; CATALASE; CELL MEMBRANE PROTEIN; CHAPERONIN; CYTOSKELETON PROTEIN; HEMOGLOBIN F; HYDROXYUREA; PROTEOME; THIOREDOXIN PEROXIDASE; TYROSINE; ANTISICKLING AGENT; MEMBRANE PROTEIN;

CONCENTRATION (PARAMETERS); CONFERENCE PAPER; DRUG MECHANISM; ERYTHROCYTE MEMBRANE; GEL ELECTROPHORESIS; HEMOGLOBIN BLOOD LEVEL; HUMAN; IMMUNOBLOTTING; IN VITRO STUDY; INCUBATION TIME; PHARMACOGENETICS; PROTEIN PHOSPHORYLATION; PROTEOMICS; SICKLE CELL ANEMIA; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL DIFFERENCE IN GEL ELECTROPHORESIS; BLOOD; DRUG EFFECT; ENZYME ACTIVATION; ERYTHROCYTE DISORDER; GENETICS; HOMOZYGOTE; METABOLISM; METHODOLOGY; PEPTIDE MAPPING; PROTEIN PROCESSING; REVIEW;

ANEMIA, SICKLE CELL; ANTISICKLING AGENTS; CATALASE; ENZYME ACTIVATION; ERYTHROCYTE MEMBRANE; ERYTHROCYTES, ABNORMAL; HOMOZYGOTE; HUMANS; HYDROXYUREA; MEMBRANE PROTEINS; PEPTIDE MAPPING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOME; PROTEOMICS;

EID: 58749089719     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.3181/0805-S-149     Document Type: Conference Paper

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