메뉴 건너뛰기




Volumn 54, Issue 6, 2014, Pages 771-780

Molecular Basis of Taste Sense: Involvement of GPCR Receptors

Author keywords

GPCR; oral; signal transduction; Taste sensing

Indexed keywords

G PROTEIN COUPLED RECEPTORS; GPCR; INTRACELLULAR SIGNALING; MOLECULAR BASIS; ORAL; PHARMACEUTICAL INDUSTRY; TASTE PERCEPTIONS; TASTE SENSING;

EID: 84884674887     PISSN: 10408398     EISSN: 15497852     Source Type: Journal    
DOI: 10.1080/10408398.2011.606929     Document Type: Article
Times cited : (29)

References (90)
  • 2
    • 0037423292 scopus 로고    scopus 로고
    • Bitter-sweet solution in taste transduction
    • Amrein, H. and Bray, S. 2003. Bitter-sweet solution in taste transduction. Cell., 112: 283 - 287.
    • (2003) Cell. , vol.112 , pp. 283-287
    • Amrein, H.1    Bray, S.2
  • 5
    • 34250863772 scopus 로고    scopus 로고
    • Gustatory expression profiles of the full complement of human bitter taste receptor genes
    • Behrens, M., Foerster, S., Staehler, F., Raguse, J.-D. and Meyerhof, W. 2006. Gustatory expression profiles of the full complement of human bitter taste receptor genes. Chem. Senses., 31 (8): E72
    • (2006) Chem. Senses. , vol.31 , Issue.8
    • Behrens, M.1    Foerster, S.2    Staehler, F.3    Raguse, J.-D.4    Meyerhof, W.5
  • 6
    • 0033118334 scopus 로고    scopus 로고
    • Molecular tinkering of G protein-coupled receptors: An evolutionary success
    • Bockaert, J. and Pin, J. P. 1999. Molecular tinkering of G protein-coupled receptors: An evolutionary success. EMBO J., 18: 1723 - 1729.
    • (1999) EMBO J. , vol.18 , pp. 1723-1729
    • Bockaert, J.1    Pin, J.P.2
  • 10
    • 33751084573 scopus 로고    scopus 로고
    • The receptors and cells for mammalian taste
    • Chandrashekar, J., Hoon, M. A., Ryba, N. J. P. and Zuker, C. S. 2006. The receptors and cells for mammalian taste. Nature., 444: 288 - 294.
    • (2006) Nature. , vol.444 , pp. 288-294
    • Chandrashekar, J.1    Hoon, M.A.2    Ryba, N.J.P.3    Zuker, C.S.4
  • 12
    • 0033993988 scopus 로고    scopus 로고
    • A metabotropic glutamate receptor variant functions as a taste receptor
    • Chaudhari, N., Landin, A. M. and Roper, S. D. 2000. A metabotropic glutamate receptor variant functions as a taste receptor. Nat. Neurosci., 3: 113 - 119.
    • (2000) Nat. Neurosci. , vol.3 , pp. 113-119
    • Chaudhari, N.1    Landin, A.M.2    Roper, S.D.3
  • 13
    • 33645996719 scopus 로고    scopus 로고
    • Mouse taste cells with G protein-coupled taste receptors lack voltage-gated calcium channels and SNAP-25
    • DOI: 10.1186/1741-7007-4-7
    • Clapp, T. R., Medler, K. F., Damak, S., Margolskee, R. F. and Kinnamon, S. C. 2006. Mouse taste cells with G protein-coupled taste receptors lack voltage-gated calcium channels and SNAP-25. BMC Biol., 4: 7 DOI: 10.1186/1741-7007-4-7.
    • (2006) BMC Biol. , vol.4 , pp. 7
    • Clapp, T.R.1    Medler, K.F.2    Damak, S.3    Margolskee, R.F.4    Kinnamon, S.C.5
  • 16
    • 0034677645 scopus 로고    scopus 로고
    • The physiology of taste
    • Dulac, C. 2000. The physiology of taste. Cell., 100: 607 - 610.
    • (2000) Cell. , vol.100 , pp. 607-610
    • Dulac, C.1
  • 17
    • 30944467752 scopus 로고    scopus 로고
    • Reduction in voltage-gated K+ currents in primary cultured rat pancreatic beta-cells by linoleic acids
    • Feng, D. D., Luo, Z., Roh, S. G., Hernandez, M., Tawadros, N., Keating, D. J. and Chen, C. 2006. Reduction in voltage-gated K+ currents in primary cultured rat pancreatic beta-cells by linoleic acids. Endocrinology., 147: 674 - 682.
    • (2006) Endocrinology. , vol.147 , pp. 674-682
    • Feng, D.D.1    Luo, Z.2    Roh, S.G.3    Hernandez, M.4    Tawadros, N.5    Keating, D.J.6    Chen, C.7
  • 18
    • 0032042756 scopus 로고    scopus 로고
    • G protein-coupled receptor adaptation mechanisms
    • Ferguson, S. S. G. and Caron, M. G. 1998. G protein-coupled receptor adaptation mechanisms. Semin. Cell Dev. Biol., 9: 119 - 127.
    • (1998) Semin. Cell Dev. Biol. , vol.9 , pp. 119-127
    • Ferguson, S.S.G.1    Caron, M.G.2
  • 19
    • 7644238945 scopus 로고    scopus 로고
    • The TRPM ion channel subfamily: Molecular, biophysical and functional features
    • Fleig, A. and Penner, R. 2004. The TRPM ion channel subfamily: Molecular, biophysical and functional features. Trends Pharmacol. Sci., 25: 633 - 639.
    • (2004) Trends Pharmacol. Sci. , vol.25 , pp. 633-639
    • Fleig, A.1    Penner, R.2
  • 22
    • 0038024615 scopus 로고    scopus 로고
    • The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups and fingerprints
    • Fredriksson, R., Lagerström, M. C., Lundin, L.-G. and Schiöth, H. B. 2003. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups and fingerprints. Mol. Pharmacol., 63: 1256 - 1272.
    • (2003) Mol. Pharmacol. , vol.63 , pp. 1256-1272
    • Fredriksson, R.1    Lagerström, M.C.2    Lundin, L.-G.3    Schiöth, H.B.4
  • 23
    • 0030435708 scopus 로고    scopus 로고
    • Interactions between umami and other flavor characteristics
    • Fuke, S. and Ueda, Y. 1996. Interactions between umami and other flavor characteristics. Trends Food Sci. Technol., 7: 407 - 411.
    • (1996) Trends Food Sci. Technol. , vol.7 , pp. 407-411
    • Fuke, S.1    Ueda, Y.2
  • 26
    • 30944455097 scopus 로고    scopus 로고
    • The free fatty acid receptor GPR40 generates excitement in pancreatic beta-cells
    • Gromada, J. 2006. The free fatty acid receptor GPR40 generates excitement in pancreatic beta-cells. Endocrinology., 147: 672 - 673.
    • (2006) Endocrinology. , vol.147 , pp. 672-673
    • Gromada, J.1
  • 27
    • 0142039027 scopus 로고    scopus 로고
    • Global analysis of G-protein-coupled receptor signaling in human tissues
    • Hakak, Y., Shrestha, D., Goegel, M. C., Behan, D. P. and Chalmers, D. T. 2003. Global analysis of G-protein-coupled receptor signaling in human tissues. FEBS Lett., 550: 11 - 17.
    • (2003) FEBS Lett. , vol.550 , pp. 11-17
    • Hakak, Y.1    Shrestha, D.2    Goegel, M.C.3    Behan, D.P.4    Chalmers, D.T.5
  • 31
    • 0033582645 scopus 로고    scopus 로고
    • Putative mammalian taste receptors: A class of taste-specific GPCRs with distinct topographic selectivity
    • Hoon, M. A., Adler, E., Lindemeier, J., Battey, J. F., Ryba, N. J. P. and Zuker, C. S. 1999. Putative mammalian taste receptors: A class of taste-specific GPCRs with distinct topographic selectivity. Cell., 96: 541 - 551.
    • (1999) Cell. , vol.96 , pp. 541-551
    • Hoon, M.A.1    Adler, E.2    Lindemeier, J.3    Battey, J.F.4    Ryba, N.J.P.5    Zuker, C.S.6
  • 33
    • 0036189809 scopus 로고    scopus 로고
    • G protein-coupled receptor signalling and cross-talk. Achieving rapidity and specificity
    • Hur, E.-M. and Kim, K.-T. 2002. G protein-coupled receptor signalling and cross-talk. Achieving rapidity and specificity. Cell Signal., 14: 397 - 405.
    • (2002) Cell Signal. , vol.14 , pp. 397-405
    • Hur, E.-M.1    Kim, K.-T.2
  • 34
    • 59449083289 scopus 로고    scopus 로고
    • Molecular mechanisms of taste transduction in vertebrates
    • Ishimaru, Y. 2009. Molecular mechanisms of taste transduction in vertebrates. Odontology., 97: 1 - 7.
    • (2009) Odontology. , vol.97 , pp. 1-7
    • Ishimaru, Y.1
  • 35
    • 65349175064 scopus 로고    scopus 로고
    • Transient receptor potential (TRP) channels and taste sensation
    • Ishimaru, Y. and Matsunami, H. 2009. Transient receptor potential (TRP) channels and taste sensation. J. Dent. Res., 88: 212 - 218.
    • (2009) J. Dent. Res. , vol.88 , pp. 212-218
    • Ishimaru, Y.1    Matsunami, H.2
  • 36
    • 26644458124 scopus 로고    scopus 로고
    • Identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit T1R3
    • Jiang, P., Cui, M., Zhao, B., Snyder, L. A., Benard, L. M. J., Osman, R., Max, M. and Margolskee, R. F. 2005. Identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit T1R3. J. Biol. Chem., 280: 34296 - 34305.
    • (2005) J. Biol. Chem. , vol.280 , pp. 34296-34305
    • Jiang, P.1    Cui, M.2    Zhao, B.3    Snyder, L.A.4    Benard, L.M.J.5    Osman, R.6    Max, M.7    Margolskee, R.F.8
  • 38
    • 60549103018 scopus 로고    scopus 로고
    • Oro-sensory perception of dietary lipids: New insights into the fat taste transduction
    • Khan, N. A. and Besnard, P. 2009. Oro-sensory perception of dietary lipids: New insights into the fat taste transduction. Biochim. Biophys. Acta., 1791: 149 - 155.
    • (2009) Biochim. Biophys. Acta. , vol.1791 , pp. 149-155
    • Khan, N.A.1    Besnard, P.2
  • 40
    • 0030513706 scopus 로고    scopus 로고
    • Taste transduction: Linkage between molecular mechanisms and psychophysics
    • Kinnamon, S. C. 1996. Taste transduction: Linkage between molecular mechanisms and psychophysics. Food Qual. Prefer., 7: 153 - 159.
    • (1996) Food Qual. Prefer. , vol.7 , pp. 153-159
    • Kinnamon, S.C.1
  • 41
    • 70349565002 scopus 로고    scopus 로고
    • Umami taste transduction mechanisms
    • Kinnamon, S. C. 2009. Umami taste transduction mechanisms. Am. J. Clin. Nutr., 90: 753S - 755S.
    • (2009) Am. J. Clin. Nutr. , vol.90
    • Kinnamon, S.C.1
  • 43
    • 0037423719 scopus 로고    scopus 로고
    • A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs
    • Kotarsky, K., Nilsson, N. E., Flodgren, E., Owman, C. and Olde, B. 2003. A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs. Biochem. Biophys. Res. Commun., 301: 406 - 410.
    • (2003) Biochem. Biophys. Res. Commun. , vol.301 , pp. 406-410
    • Kotarsky, K.1    Nilsson, N.E.2    Flodgren, E.3    Owman, C.4    Olde, B.5
  • 44
    • 3042798261 scopus 로고    scopus 로고
    • Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: Molecular modeling and mutagenesis approaches to receptor structure and function
    • Kristiansen, K. 2004. Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: Molecular modeling and mutagenesis approaches to receptor structure and function. Pharmacol. Ther., 103: 21 - 80.
    • (2004) Pharmacol. Ther. , vol.103 , pp. 21-80
    • Kristiansen, K.1
  • 45
    • 0022993799 scopus 로고
    • Identification of specific transducin alpha subunits in retinal rod and cone photoreceptors
    • Lerea, C. L., Somers, D. E., Hurley, J. B., Klock, I. B. and Bunt-Milam, A. H. 1986. Identification of specific transducin alpha subunits in retinal rod and cone photoreceptors. Science., 234: 77 - 80.
    • (1986) Science. , vol.234 , pp. 77-80
    • Lerea, C.L.1    Somers, D.E.2    Hurley, J.B.3    Klock, I.B.4    Bunt-Milam, A.H.5
  • 46
    • 0035974858 scopus 로고    scopus 로고
    • Sweet successes
    • Lewcock, J. W. and Reed, R. R. 2001. Sweet successes. Neuron., 31: 515 - 517.
    • (2001) Neuron. , vol.31 , pp. 515-517
    • Lewcock, J.W.1    Reed, R.R.2
  • 47
    • 70349577136 scopus 로고    scopus 로고
    • T1R receptors mediate mammalian sweet and umami taste
    • Li, X. 2009. T1R receptors mediate mammalian sweet and umami taste. Am. J. Clin. Nutr., 90: 733S - 737S.
    • (2009) Am. J. Clin. Nutr. , vol.90
    • Li, X.1
  • 49
    • 33846901590 scopus 로고    scopus 로고
    • TRPM5 and taste transduction
    • Liman, E. R. 2007. TRPM5 and taste transduction. Handb. Exp. Pharmacol., 179: 285 - 296.
    • (2007) Handb. Exp. Pharmacol. , vol.179 , pp. 285-296
    • Liman, E.R.1
  • 50
    • 0030266428 scopus 로고    scopus 로고
    • Chemoreception: Tasting the sweet and the bitter
    • Lindemann, B. 1996. Chemoreception: Tasting the sweet and the bitter. Curr. Biol., 6: 1234 - 1237.
    • (1996) Curr. Biol. , vol.6 , pp. 1234-1237
    • Lindemann, B.1
  • 51
    • 0035855939 scopus 로고    scopus 로고
    • Receptors and transduction in taste
    • Lindemann, B. 2001. Receptors and transduction in taste. Nature., 413: 219 - 225.
    • (2001) Nature. , vol.413 , pp. 219-225
    • Lindemann, B.1
  • 53
    • 67650686837 scopus 로고    scopus 로고
    • Bitter peptides and bitter taste receptors
    • Maehashi, K. and Huang, L. 2009. Bitter peptides and bitter taste receptors. Cell. Mol. Life Sci., 66: 1661 - 1671.
    • (2009) Cell. Mol. Life Sci. , vol.66 , pp. 1661-1671
    • Maehashi, K.1    Huang, L.2
  • 54
    • 0037016771 scopus 로고    scopus 로고
    • Molecular mechanisms of bitter and sweet taste transduction
    • Margolskee, R. F. 2002. Molecular mechanisms of bitter and sweet taste transduction. J. Biol. Chem., 277: 1 - 4.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1-4
    • Margolskee, R.F.1
  • 56
    • 0034611738 scopus 로고    scopus 로고
    • A family of candidate taste receptors in human and mouse
    • Matsunami, H., Montmayeur, J.-P. and Buck, L. B. 2000. A family of candidate taste receptors in human and mouse. Nature., 404: 601 - 604.
    • (2000) Nature. , vol.404 , pp. 601-604
    • Matsunami, H.1    Montmayeur, J.-P.2    Buck, L.B.3
  • 57
    • 67749101392 scopus 로고    scopus 로고
    • Is there a fatty acid taste?
    • Mattes, R. D. 2009. Is there a fatty acid taste?. Annu. Rev. Nutr., 29: 305 - 327.
    • (2009) Annu. Rev. Nutr. , vol.29 , pp. 305-327
    • Mattes, R.D.1
  • 58
    • 79960397923 scopus 로고    scopus 로고
    • Accumulating evidence supports a taste component for free fatty acids in humans
    • Mattes, R. D. 2011. Accumulating evidence supports a taste component for free fatty acids in humans. Physiol. Behav., 104: 624 - 631.
    • (2011) Physiol. Behav. , vol.104 , pp. 624-631
    • Mattes, R.D.1
  • 60
    • 34047250135 scopus 로고    scopus 로고
    • Umami: A delicious flavor formed by convergence of taste and olfactory pathways in the human brain
    • McCabe, C. and Rolls, E. T. 2007. Umami: A delicious flavor formed by convergence of taste and olfactory pathways in the human brain. Eur. J. Neurosci., 25: 1855 - 1864.
    • (2007) Eur. J. Neurosci. , vol.25 , pp. 1855-1864
    • McCabe, C.1    Rolls, E.T.2
  • 62
    • 33745976773 scopus 로고    scopus 로고
    • 2+ signaling
    • 2+ signaling. Cell Calcium., 40: 261 - 275.
    • (2006) Cell Calcium. , vol.40 , pp. 261-275
    • Minke, B.1
  • 63
    • 1842464122 scopus 로고    scopus 로고
    • Genes and ligands for odorant, vomeronasal and taste receptors
    • Mombaerts, P. 2004. Genes and ligands for odorant, vomeronasal and taste receptors. Nature., 5: 263 - 278.
    • (2004) Nature. , vol.5 , pp. 263-278
    • Mombaerts, P.1
  • 66
    • 27644568166 scopus 로고    scopus 로고
    • Distinct contributions of T1R2 and T1R3 taste receptor subunits to the detection of sweet stimuli
    • Nie, Y., Vigues, S., Hobbs, J. R., Conn, G. L. and Munger, S. D. 2005. Distinct contributions of T1R2 and T1R3 taste receptor subunits to the detection of sweet stimuli. Curr. Biol., 15: 1948 - 1952.
    • (2005) Curr. Biol. , vol.15 , pp. 1948-1952
    • Nie, Y.1    Vigues, S.2    Hobbs, J.R.3    Conn, G.L.4    Munger, S.D.5
  • 67
    • 72049126087 scopus 로고    scopus 로고
    • G Protein-coupled receptors as targets for drug design
    • Nuez Veulens, A. and Rodríguez, R. 2009. G Protein-coupled receptors as targets for drug design. Biotecnol. Apl., 26: 24 - 33.
    • (2009) Biotecnol. Apl. , vol.26 , pp. 24-33
    • Nuez Veulens, A.1    Rodríguez, R.2
  • 69
    • 34247568273 scopus 로고    scopus 로고
    • The pharmacology and signaling of bitter, sweet and umami taste sensing
    • Palmer, R. K. 2007. The pharmacology and signaling of bitter, sweet and umami taste sensing. Mol. Interv., 7: 87 - 98.
    • (2007) Mol. Interv. , vol.7 , pp. 87-98
    • Palmer, R.K.1
  • 70
    • 6944241419 scopus 로고    scopus 로고
    • Divergence of T2R chemosensory receptor families in humans, bonobos, and chimpanzees
    • Parry, C. M., Erkner, A. and le Coutre, J. 2004. Divergence of T2R chemosensory receptor families in humans, bonobos, and chimpanzees. Proc. Natl. Acad. Sci, 101: 14830 - 14834.
    • (2004) Proc. Natl. Acad. Sci , vol.101 , pp. 14830-14834
    • Parry, C.M.1    Erkner, A.2    le Coutre, J.3
  • 72
    • 8544242989 scopus 로고    scopus 로고
    • Identification of ligands for two human bitter T2R receptors
    • Pronin, A. N., Tang, H., Connor, J. and Keung, W. 2004. Identification of ligands for two human bitter T2R receptors. Chem. Senses., 29: 583 - 593.
    • (2004) Chem. Senses. , vol.29 , pp. 583-593
    • Pronin, A.N.1    Tang, H.2    Connor, J.3    Keung, W.4
  • 74
    • 34250809680 scopus 로고    scopus 로고
    • Signal transduction and information processing in mammalian taste buds
    • Roper, S. D. 2007. Signal transduction and information processing in mammalian taste buds. Pflügers Arch., 454: 759 - 776.
    • (2007) Pflügers Arch. , vol.454 , pp. 759-776
    • Roper, S.D.1
  • 75
    • 0035023861 scopus 로고    scopus 로고
    • Identification of a novel member of the T1R family of putative taste receptors
    • Sainz, E., Korley, J. N., Battey, J. F. and Sullivan, S. L. 2001. Identification of a novel member of the T1R family of putative taste receptors. J. Neurochem., 77: 896 - 903.
    • (2001) J. Neurochem. , vol.77 , pp. 896-903
    • Sainz, E.1    Korley, J.N.2    Battey, J.F.3    Sullivan, S.L.4
  • 76
    • 33646526072 scopus 로고    scopus 로고
    • I want a new drug: G-protein-coupled receptors in drug development
    • Schlyer, S. and Horuk, R. 2006. I want a new drug: G-protein-coupled receptors in drug development. Drug Discov. Today, 11: 481 - 493.
    • (2006) Drug Discov. Today , vol.11 , pp. 481-493
    • Schlyer, S.1    Horuk, R.2
  • 77
    • 30744472932 scopus 로고    scopus 로고
    • Contrasting modes of evolution between vertebrate sweet/umami receptor genes and bitter receptor genes
    • Shi, P. and Zhang, J. 2006. Contrasting modes of evolution between vertebrate sweet/umami receptor genes and bitter receptor genes. Mol. Biol. Evol., 23: 292 - 300.
    • (2006) Mol. Biol. Evol. , vol.23 , pp. 292-300
    • Shi, P.1    Zhang, J.2
  • 78
    • 65449179899 scopus 로고    scopus 로고
    • Extraordinary diversity of chemosensory receptor gene repertoires among vertebrates
    • Shi, P. and Zhang, J. 2009. Extraordinary diversity of chemosensory receptor gene repertoires among vertebrates. Results Probl. Cell Differ., 47: 1 - 23.
    • (2009) Results Probl. Cell Differ. , vol.47 , pp. 1-23
    • Shi, P.1    Zhang, J.2
  • 79
    • 0032223662 scopus 로고    scopus 로고
    • Gustducin and its role in taste
    • Spielman, A. I. 1998. Gustducin and its role in taste. J. Dent. Res., 77: 539 - 544.
    • (1998) J. Dent. Res. , vol.77 , pp. 539-544
    • Spielman, A.I.1
  • 81
    • 79952702415 scopus 로고    scopus 로고
    • Fatty acid detection during food consumption and digestion: Associations with ingestive behavior and obesity
    • Stewart, J. E., Feinle-Bisset, C. and Keas, R. S. J. 2011. Fatty acid detection during food consumption and digestion: Associations with ingestive behavior and obesity. Prog. Lipid Res., 50: 225 - 233.
    • (2011) Prog. Lipid Res. , vol.50 , pp. 225-233
    • Stewart, J.E.1    Feinle-Bisset, C.2    Keas, R.S.J.3
  • 82
    • 33748481774 scopus 로고    scopus 로고
    • Taste perception and coding in the periphery
    • Sugita, M. 2006. Taste perception and coding in the periphery. Cell Mol. Life Sci., 63: 2000 - 2015.
    • (2006) Cell Mol. Life Sci. , vol.63 , pp. 2000-2015
    • Sugita, M.1
  • 84
    • 67149138301 scopus 로고    scopus 로고
    • Sweet, bitter and umami receptors: A complex relationship
    • Temussi, P. A. 2009. Sweet, bitter and umami receptors: A complex relationship. Trends Biochem. Sci., 34: 296 - 302.
    • (2009) Trends Biochem. Sci. , vol.34 , pp. 296-302
    • Temussi, P.A.1
  • 86
    • 0034115332 scopus 로고    scopus 로고
    • Sweet taste transduction in hamster: Role of protein kinases
    • Varkevisser, B. and Kinnamon, S. C. 2000. Sweet taste transduction in hamster: Role of protein kinases. J. Neurophysiol., 83: 2526 - 2532.
    • (2000) J. Neurophysiol. , vol.83 , pp. 2526-2532
    • Varkevisser, B.1    Kinnamon, S.C.2
  • 87
    • 0037133261 scopus 로고    scopus 로고
    • Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells
    • Wu, S. V., Rozengurt, N., Yang, M., Young, S. H., Sinnett-Smith, J. and Rozengurt, E. 2002. Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells. Proc. Natl. Acad. Sci, 99: 2392 - 2397.
    • (2002) Proc. Natl. Acad. Sci , vol.99 , pp. 2392-2397
    • Wu, S.V.1    Rozengurt, N.2    Yang, M.3    Young, S.H.4    Sinnett-Smith, J.5    Rozengurt, E.6
  • 88
    • 33644504886 scopus 로고    scopus 로고
    • Taste receptor cells responding with action potentials to taste stimuli and their molecular expression of taste related genes
    • Yoshida, R., Sanematsu, K., Shigemura, N., Yasumatsu, K. and Ninomiya, Y. 2005. Taste receptor cells responding with action potentials to taste stimuli and their molecular expression of taste related genes. Chem. Senses., 30: i19 - i20.
    • (2005) Chem. Senses. , vol.30
    • Yoshida, R.1    Sanematsu, K.2    Shigemura, N.3    Yasumatsu, K.4    Ninomiya, Y.5
  • 89
    • 0037423367 scopus 로고    scopus 로고
    • Coding of sweet, bitter, and umami tastes: Different receptor cells sharing similar signaling pathways
    • Zhang, Y., Hoon, M. A., Chandrashekar, J., Mueller, K. L., Cook, B., Wu, D., Zuker, C. S. and Ryba, N. P. J. 2003. Coding of sweet, bitter, and umami tastes: Different receptor cells sharing similar signaling pathways. Cell., 112: 293 - 301.
    • (2003) Cell. , vol.112 , pp. 293-301
    • Zhang, Y.1    Hoon, M.A.2    Chandrashekar, J.3    Mueller, K.L.4    Cook, B.5    Wu, D.6    Zuker, C.S.7    Ryba, N.P.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.