Dynamic cross talk between S1P and CXCL12 regulates hematopoietic stem cells migration, development and bone remodeling

Pharmaceuticals

Volumn 6, Issue 9, 2013, Pages 1145-1169

  Golan, Karin ^a   Kollet, Orit ^a   Lapidot, Tsvee ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Bone remodeling; CXCL12 CXCR4; Hematopoietic stem cells; Mobilization; S1P

Indexed keywords

5 (4 PHENYL 5 TRIFLUOROMETHYL 2 THIENYL) 3 (3 TRIFLUOROMETHYLPHENYL) 1,2,4 OXADIAZOLE; CATHEPSIN K; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR7; COLONY STIMULATING FACTOR 1; FINGOLIMOD; GELATINASE B; GRANULOCYTE COLONY STIMULATING FACTOR; JAGGED1; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NOTCH1 RECEPTOR; OSTEOCLAST DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PLERIXAFOR; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE KINASE 1; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR FKHRL1; UNINDEXED DRUG; UROKINASE; WNT PROTEIN;

BONE REMODELING; BONE TURNOVER; CELL DIFFERENTIATION; CELL MATURATION; CELL MIGRATION; CELL MOTILITY; DRUG EFFECT; ENZYME INHIBITION; HEMATOPOIETIC STEM CELL; HUMAN; LEUKOCYTE; MULTIPLE SCLEROSIS; NONHUMAN; OSTEOBLAST; OSTEOCLAST; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; STEM CELL MOBILIZATION; STEM CELL NICHE; STROMA CELL;

EID: 84884540619     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph6091145     Document Type: Review

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