Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient

Biochemical Journal

Volumn 397, Issue 3, 2006, Pages 461-471

  Venkataraman, Krishnan ^a   Thangada, Shobha ^a   Michaud, Jason ^a   Oo, Myat Lin ^a   Ai, Youxi ^a   Lee, Yong Moon ^a   Wu, Mingtao ^a   Parikh, Nehal S ^b   Khan, Faraz ^a   Proia, Richard L ^c   Hla, Timothy ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b Farmington   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Extracellular export; Platelet poor plasma; Platelet rich plasma; Sphingosine 1 phosphate; Sphingosine 1 phosphate (S1P) gradient; Sphingosine kinase

Indexed keywords

CELLS; ENZYME IMMOBILIZATION; GRADIENT METHODS; IMMUNOLOGY; PHOSPHATES; PHYSIOLOGICAL MODELS; PLASMA ACCELERATORS;

HUMAN EMBRYONIC KIDNEY CELLS; IMMUNE CELL TRAFFICKING; SPHINGOSINE KINASES; VASCULAR ENDOTHELIAL CELLS;

ENZYMES;

SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE 1;

ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME RELEASE; ENZYME SYNTHESIS; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASCULAR ENDOTHELIUM;

ANIMALS; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; ENDOTHELIUM, VASCULAR; EXTRACELLULAR SPACE; HUMANS; INTRACELLULAR SPACE; ISOENZYMES; LYSOPHOSPHOLIPIDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN TRANSPORT; RECEPTORS, LYSOSPHINGOLIPID; SPHINGOSINE;

MAMMALIA;

EID: 33746897677     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060251     Document Type: Article

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