Osteoclast-mediated bone resorption is stimulated during short-term administration of granulocyte colony-stimulating factor but is not responsible for hematopoietic progenitor cell mobilization

Blood

Volumn 92, Issue 9, 1998, Pages 3465-3473

  Takamatsu, Yasushi ^b   Simmons, Paul J ^b   Moore, Robert J ^b   Morris, Howard A ^b   To, Luen B ^b   Lévesque, Jean Pierre ^a  

^a HANSON INSTITUTE   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CALCIUM ION; DEOXYPYRIDINOLINE; FIBRONECTIN; OSTEOCALCIN; PAMIDRONIC ACID; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 3; RECOMBINANT STEM CELL FACTOR; VERY LATE ACTIVATION ANTIGEN 5;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE STRUCTURE; BONE TURNOVER; CALCIUM TRANSPORT; CELL ADHESION; CLINICAL ARTICLE; COLONY FORMING CELL; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MALE; NONHUMAN; OSSIFICATION; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; TRANSGENIC MOUSE;

EID: 0032212144     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.9.3465.421k35_3465_3473     Document Type: Article

References (55)

1. Tavassoli M, Hardy CL: Molecular basis of homing of intravenously transplanted stem cells to the marrow. Blood 76:1059, 1990
2. Simmons PJ, Lévesque JP, Zannettino ACW: Cell adhesion molecules and their role in regulating haemopoiesis. Baillère's Clin Hematol 10:485, 1997
3. Simmons PJ, Mesinosky B, Longenecker BM, Berenson R, Torok-Storb B, Gallatin WM: Vascular-cell adhesion molecule-1 expressed by bone marrow stromal cells mediated the binding of hematopoietic progenitor cells. Blood 80:388, 1992
4. Teixidó J, Hemler ME, Greenberger JS, Anklessaria P: Role of β1 and β2 integrins in the adhesion of human CD34hi cells to bone marrow stroma. J Clin Invest 90:358, 1993
5. Lévesque JP, Leavesley DI, Niutta S, Vadas M, Simmons PJ: Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins. J Exp Med 181:1805, 1995
6. Williams DA, Rios M, Stephans C, Patel VP: Fibronectin and VLA-4 in haematopoietic stem cell-microenvironment interactions. Nature 352:438, 1991
7. Hirsch E, Iglesias A, Potocnik AJ, Hartmann U, Fassler R: Impaired migration but not differentiation of haemopoietic stem cells in the absence of β1 integrins. Nature 380:171, 1996
8. Papayannopoulou T, Nakamoto B: Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrin. Proc Natl Acad Sci USA 90:9374, 1993
9. To LB, Haylock DN, Simmons PJ, Juttner CA: The biology and clinical uses of blood stem cells. Blood 89:2233, 1997
10. Sheridan WP, Begley CG, Juttner CA, Szer J, To LB, Maher D, McGrath KM, Morstyn G, Fox RM: Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy. Lancet 339:640, 1992
11. Matsunaga T, Sakamaki S, Kongo Y, Ohi S, Hirayama Y, Niitsu Y: Recombinat human granulocyte colony-stimulating factor can mobilize sufficient amounts of peripheral blood stem cells in healthy volunteers for allogeneic transplantation. Bone Marrow Transplant 11:103, 1993
12. Möhle R, Haas R, Hunstein W: Expression of adhesion molecules and c-kit on CD34+ hematopoietic progenitor cells: Comparison of cytokine-mobilized blood stem cells with normal bone marrow and peripheral blood. J Hematother 2:483, 1993
13. + cells predict a rapid platelet recovery after peripheral blood stem cell transplantation. Blood 85:3313, 1995
14. Turner ML, Mcllwaine K, Anthony RS, Parker AC: Differential expression of cell adhesion molecules by human hematopoietic progenitor cells from bone marrow and mobilized adult peripheral blood. Stem Cells 13:311, 1995
15. Lévesque J, Haylock D, Simmons P: Cytokine regulation of proliferation and cell adhesion are correlated events in human CD34+ hemopoietic progenitors. Blood 88:1168, 1996
16. Kovach NL, Lin N, Yednock T, Harlan JM, Broudy VC: Stem cell factor modulates activity of α4β1 and α5β1 integrins expressed on hematopoietic cell lines. Blood 85:159, 1995
17. Cui L, Ramstjell V, Borge OJ, Veiby OP, Lok S, Jacobsen SE: Thrombopoietin promotes adhesion of primitive human hemopoietic cells to fibronectin and vascular cell adhesion molecule-1: Role of activation of very late antigen (VLA)-4 and VLA-5. J Immunol 159:1961, 1997
18. Gailit J, Ruoslahti E: Regulation of fibronectin receptor affinity by divalent cations. J Biol Chem 263:12927, 1988
19. D'Souza S, Haas T, Piotrowicz R, Byers-Ward V, McGrath D, Soule H, Cierniewski C, Plow E, Smith J: Ligand and cation binding are dual functions of a discrete segment of the integrin β3 subunit: Cation displacement is involved in ligand binding. Cell 79:659, 1994
20. 2+. J Biol Chem 270:26270, 1995
21. Silver I, Murrils R, Etherington D: Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts. Exp Cell Res 175:266, 1988
22. Takamatsu Y, Simmons PJ, Lévesque JP: Dual control by divalent cations and mitogenic cytokines of α4β1 and α5β1 integrin affinity on human hemopoietic cells. Cell Adhes Commun 5:349, 1998
23. Bonilla MA, Dale D, Zeidler C, Last L, Reiter A, Ruggeiro M, Davis M, Koci B, Hammond W, Gillio A, Weite K: Long-term safety of treatment with recombinant human granulocyte colony-stimulating factor (r-metHuG-CSF) in patients with severe congenital neutropenias. Br J Haematol 88:723, 1994
24. Bishop J: Osteoporosis in severe congenital neutropenia treated with granulocyte colony-stimulating factor. Br J Haematol 89:927, 1995
25. Lee MY, Fukunaga R, Lee TJ, Lottsfeldt JL, Nagata S: Bone modulation in sustained hematopoietic stimulation in mice. Blood 77:2135, 1991
26. Soshi S, Takahashi HE, Tanizawa T, Endo N, Fujimoto R, Murota K: Effect of recombinant granulocyte colony-stimulating factor (rhG-CSF) on rat bone: Inhibition of bone formation at the endosteal surface of vertebre and tibia. Calcif Tissue Int 58:337, 1996
27. Takahashi T, Wada T, Mori M, Kokai Y, Ishii S: Overexpression of the granulocyte colony-stimulating factor gene leads to osteoporosis in mice. Lab Invest 74:827, 1996
28. + cells into the myeloid lineage. Blood 80:1405, 1992
29. 3-induced stimulated bone turnover in the mouse. Calcif Tissue Int 37:268, 1985
30. Kamel S, Brazier M, Desmet G, Picard C, Mennencier I, Sebert J: High performance liquid Chromatographic determination of 3-hydroxypyridinium derivertives as new markers of bone resorption. J Chromatog 54:255, 1992
31. Parkinson IH, Parsons AM, Moore RJ: The histochemical localization of osteoclasts in EDTA-decalcified bone. J Histotech 13:189, 1990
32. Molineux G, Pojda Z, Dexter TM: A comparison of hematopoiesis in normal and splenectomized mice treated with granulocyte colony-stimulating factor. Blood 75:563, 1990
33. Roberts AW, Foote S, Alexander WS, Scott C, Robb L, Metcalf D: Genetic influences determining progenitor cell mobilization and leukocytosis induced by granulocyte colony-stimulating factor. Blood 89:2736, 1997.
34. Lord BI, Testa NG, Hendry JH: The relative spatial distribution of CFU-S and CFU-C in the normal mouse femur. Blood 46:65, 1975
35. Weiss L: The hematopoietic microenvirnonment of the bone marrow: An ultrastructural study of the stroma in rats. Anat Rec 186:161, 1976
36. Hauschka PV, Lian JB, Gallop PM: Direct identification of the calcium-binding amino acid γ-carboxyglutamate in mineralized tissue. Proc Natl Acad Sci USA 72:3925, 1975
37. Morris HA, Chatterton BE, Ross PD, Durbridge TC: Diagnostic procedures, in Nordin BEC, Need AG, Morris HA (eds): Metabolic Bone and Stone Disease (ed 3). Edinburgh, UK, Churchhill Livingstone, 1993, p 339
38. O'Loughlin PD: Osteocalcin, in Morris HA (ed): Biochemical Markers of Metabolic Bone Disease. Sydney, Australia, The Australian Association of Clinical Biochemists Inc, 1989, p 21
39. Delmas PD: Biochemical markers of bone turnover. J Bone Miner Res 8:S549, 1993 (suppl)
40. Tanaka S, Takahashi N, Udagawa N, Tamura T, Akatsu T, Stanley ER, Kurokawa T, Suda T: Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors. J Clin Invest 91:257, 1993
41. Quinn JMW, McGee JOD, Athanasou NA: Cellular and hormonal factors influencing monocyte differentiation to osteoclastic bone-resorbing cells. Endocrinology 134:2416, 1994
42. Purton LE, Lee MY, Torok-Storb B: Normal human peripheral blood mononuclear cells mobilized with granulocyte colony-stimulating factor have increased osteoclastogenic potential compared to nonmobilized blood. Blood 87:1802, 1996
43. Endo Y, Nakamura M, Kikuchi T, Shinoda H, Takeda Y, Nitta Y, Kumagai K: Aminoalkylbisphosphonates, potent inhibitors of bone resorption, induce a prolonged stimulation of histamine synthesis and increase macrophages, granulocytes, and osteoclasts in vivo. Calcif Tissue Int 52:248, 1993
44. Pedrazzoni M, Alfano FS, Gatti C, Fantuzzi M, Girasole G, Campanini C, Basini G, Passeri M: Acute effects of bisphosphonates on new and traditional markers of bone resorption. Calcif Tissue Int 57:25, 1995
45. Adami S, Bhalla AK, Dorizzi R, Montesanti F, Rosini S, Salvagno G, Lo Cascio V: The acute-phase response after bisphosphonate administration. Calcif Tissue Int 41:326, 1987
46. Schweitzer DH, Oostendorp-van de Ruit M, van der Pluijm G, Löwik CWGM, Papapoulos SE: Interleukin-6 and the acute phase response during treatment of patients with Paget's disease with the nitrogen-containing bisphosphonate dimethylaminohydroxypropylidene bisphosphonate. J Bone Miner Res 10:956, 1995
47. Sauty A, Pecherstorfer M, Zimmer-Roth I, Fioroni P, Juillerat L, Markert M, Ludwig H, Leuenberger P, Burckhardt P, Thiébaud D: Interleukin-6 and tumor necrosis factor α levels after bisphosphonates treatment in vitro and patients with malignancy. Bone 18:133, 1996
48. Pettengell R, Luft T, de Wynter E, Coutinho L, Young R, Fitzsimmons L, Scarffe JH, Testa NG: Effects of interleukin-6 on mobilization of primitive haemopoietic cells into the circulation. Br J Haematol 89:237, 1995
49. Berenson JR, Lichtenstein A, Porter L, Dimopoulos MA, Bordoni R, George S, Lipton A, Keller A, Ballester O, Kovacs MJ, Blacklock HA, Bell R, Simeone J, Reitsma DJ, Heffernan M, Seaman J, Knight RD: Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. N Engl J Med 334:488, 1996
50. Bible G, Roberts E, Birch M, Evans DB: PCR phenotyping of cytokines, growth factors and their receptors and bone matrix proteins in human osteoblast-like cell lines. Bone 19:437, 1996
51. Shinar DM, Sato M, Rodan G A: The effect of hemopoietic growth factors on the generation of osteoclast-like cells in mouse bone marrow cultures. Endocrinology 126:1728, 1990
52. Hofstetter W, Felix R, Cecchini MG: Colony-stimulating factors, in Bilezikian JP, Raisz LG, Rodan GA (eds): Principles of Bone Biology. San Diego, CA, Academic, 1996, p 673
53. Tamura T, Udagawa N, Takahashi N, Miyaura C, Tanaka S, Yamada Y, Koishihara Y, Ohsugi Y, Kumaki K, Taga T, Kishimoto T, Suda T: Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6. Proc Natl Acad Sci USA 90:11924, 1993
54. Suda T, Nakamura I, Jimi E, Takahashi N: Regulation of osteoclast function. J Bone Miner Res 12:869, 1997
55. Romas E, Martin TJ: Cytokines in the pathogenesis of osteoporosis. Osteoporos Int 7:S47, 1997 (suppl)