메뉴 건너뛰기




Volumn 90, Issue , 2013, Pages 160-184

Phytochemistry and biological properties of glabridin

Author keywords

Anti atherogenic; Chemical characterization; Glabridin; Metabolic syndrome; Pharmacokinetics; PhytoSERM

Indexed keywords

GLABRIDIN;

EID: 84884468967     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2013.07.003     Document Type: Review
Times cited : (214)

References (133)
  • 1
    • 84884498234 scopus 로고    scopus 로고
    • Scientific opinion on the safety of " Glavonoid ® ", an extract derived from the roots or rootstock of Glycyrrhiza glabra L., as a novel food ingredient
    • European Food Safety Authority
    • European Food Safety Authority Scientific opinion on the safety of " Glavonoid ® ", an extract derived from the roots or rootstock of Glycyrrhiza glabra L., as a novel food ingredient EFSA J 9 2011 1 27
    • (2011) EFSA J , vol.9 , pp. 1-27
  • 5
    • 84860626351 scopus 로고    scopus 로고
    • Novel phytonutrient contributors to antioxidant protection against cardiovascular disease
    • G. Riccioni, L. Speranza, M. Pesce, S. Cusenza, N. D'Orazio, and M.J. Glade Novel phytonutrient contributors to antioxidant protection against cardiovascular disease Nutrition 28 2012 605 610
    • (2012) Nutrition , vol.28 , pp. 605-610
    • Riccioni, G.1    Speranza, L.2    Pesce, M.3    Cusenza, S.4    D'Orazio, N.5    Glade, M.J.6
  • 6
    • 79952586338 scopus 로고    scopus 로고
    • Natural products and body weight control
    • J. Lee, Y. Li, C. Li, and D. Li Natural products and body weight control N Am J Med Sci 3 2011 13 19
    • (2011) N Am J Med Sci , vol.3 , pp. 13-19
    • Lee, J.1    Li, Y.2    Li, C.3    Li, D.4
  • 7
    • 67651071732 scopus 로고    scopus 로고
    • Isoflavonoids of the leguminosae
    • N.C. Veitch Isoflavonoids of the leguminosae Nat Prod Res 26 2009 776 802
    • (2009) Nat Prod Res , vol.26 , pp. 776-802
    • Veitch, N.C.1
  • 8
    • 84861905473 scopus 로고    scopus 로고
    • The role of flavonoids in root-rhizosphere signalling: Opportunities and challenges for improving plant-microbe interactions
    • S. Hassan, and U. Mathesius The role of flavonoids in root-rhizosphere signalling: opportunities and challenges for improving plant-microbe interactions J Exp Bot 63 2012 3429 3444
    • (2012) J Exp Bot , vol.63 , pp. 3429-3444
    • Hassan, S.1    Mathesius, U.2
  • 9
  • 10
    • 0034349180 scopus 로고    scopus 로고
    • Flavonoids of Leguminous Plants: Structure, Biological Activity, and Biosynthesis
    • T. Aoki, and T. Akashi Flavonoids of leguminous plants: structure, biological activity, and biosynthesis J Plant Res 113 2000 475 488 (Pubitemid 33237966)
    • (2000) Journal of Plant Research , vol.113 , Issue.1112 , pp. 475-488
    • Aoki, T.1    Akashi, T.2    Ayabe, S.3
  • 11
    • 33749336654 scopus 로고    scopus 로고
    • Identification of cDNAs encoding pterocarpan reductase involved in isoflavan phytoalexin biosynthesis in Lotus japonicus by EST mining
    • DOI 10.1016/j.febslet.2006.09.016, PII S0014579306011008
    • T. Akashi, S. Koshimizu, T. Aoki, and S.-I. Ayabe Identification of cDNAs encoding pterocarpan reductase involved in isoflavan phytoalexin biosynthesis in Lotus japonicus by EST mining FEBS Lett 580 2006 5666 5670 (Pubitemid 44498667)
    • (2006) FEBS Letters , vol.580 , Issue.24 , pp. 5666-5670
    • Akashi, T.1    Koshimizu, S.2    Aoki, T.3    Ayabe, S.-i.4
  • 12
    • 76449109205 scopus 로고    scopus 로고
    • Phenolics from Glycyrrhiza glabra roots and their PPAR-gamma ligand-binding activity
    • M. Kuroda, Y. Mimaki, S. Honda, H. Tanaka, S. Yokota, and T. Mae Phenolics from Glycyrrhiza glabra roots and their PPAR-gamma ligand-binding activity Bioorg Med Chem 18 2010 962 970
    • (2010) Bioorg Med Chem , vol.18 , pp. 962-970
    • Kuroda, M.1    Mimaki, Y.2    Honda, S.3    Tanaka, H.4    Yokota, S.5    Mae, T.6
  • 13
    • 60249101275 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a cDNA for pterocarpan 4-dimethylallyltransferase catalyzing the key prenylation step in the biosynthesis of glyceollin, a soybean phytoalexin
    • T. Akashi, K. Sasaki, T. Aoki, S. Ayabe, and K. Yazaki Molecular cloning and characterization of a cDNA for pterocarpan 4-dimethylallyltransferase catalyzing the key prenylation step in the biosynthesis of glyceollin, a soybean phytoalexin Plant Physiol 149 2009 683 693
    • (2009) Plant Physiol , vol.149 , pp. 683-693
    • Akashi, T.1    Sasaki, K.2    Aoki, T.3    Ayabe, S.4    Yazaki, K.5
  • 14
    • 0000060379 scopus 로고    scopus 로고
    • Organ specific localization of flavonoids in Glycyrrhiza glabra L
    • H. Hayashi, N. Hiraoka, Y. Ikeshiro, and H. Yamamoto Organ specific localization of flavonoids in Glycyrrhiza glabra L Plant Sci 116 1996 233 238
    • (1996) Plant Sci , vol.116 , pp. 233-238
    • Hayashi, H.1    Hiraoka, N.2    Ikeshiro, Y.3    Yamamoto, H.4
  • 15
    • 2942688004 scopus 로고    scopus 로고
    • Field survey of Glycyrrhiza plants in central asia (3). Chemical characterization of G. Glabra collected in Uzbekistan
    • DOI 10.1248/cpb.51.1338
    • H. Hayashi, S. Hattori, K. Inoue, O. Khodzhimatov, O. Ashurmetov, and M. Ito Field survey of Glycyrrhiza plants in Central Asia (3). Chemical characterization of G. glabra collected in Uzbekistan Chem Pharm Bull 51 2003 1338 1340 (Pubitemid 41685600)
    • (2003) Chemical and Pharmaceutical Bulletin , vol.51 , Issue.11 , pp. 1338-1340
    • Hayashi, H.1    Hattori, S.2    Inoue, K.3    Khodzhimatov, O.4    Ashurmetov, O.5    Ito, M.6    Honda, G.7
  • 16
    • 34447125672 scopus 로고    scopus 로고
    • Constituent properties of licorices derived from Glycyrrhiza uralensis, G. Glabra, or G. Inflata identified by genetic information
    • DOI 10.1248/bpb.30.1271
    • K. Kondo, M.S. Hiba, R.N. Akamura, T.M. Orota, and Y.S. Hoyama Constituent properties of licorices derived from Glycyrrhiza uralensis, G. glabra, or G. inflata identified by genetic information Biol Pharm Bull 30 2007 1271 1277 (Pubitemid 47037651)
    • (2007) Biological and Pharmaceutical Bulletin , vol.30 , Issue.7 , pp. 1271-1277
    • Kondo, K.1    Shiba, M.2    Nakamura, R.3    Morota, T.4    Shoyama, Y.5
  • 18
  • 20
    • 84863229428 scopus 로고    scopus 로고
    • Extraction of glabridin using imidazolium-based ionic liquids
    • X. Li, R. Guo, X. Zhang, and X. Li Extraction of glabridin using imidazolium-based ionic liquids Sep Purif Technol 88 2012 146 150
    • (2012) Sep Purif Technol , vol.88 , pp. 146-150
    • Li, X.1    Guo, R.2    Zhang, X.3    Li, X.4
  • 21
    • 61449216328 scopus 로고    scopus 로고
    • Selective solid-phase extraction of glabridin from licorice root using molecularly imprinted polymer
    • H. Yan, M. Tian, and K.H. Row Selective solid-phase extraction of glabridin from licorice root using molecularly imprinted polymer Sep Sci Technol 44 2009 359 369
    • (2009) Sep Sci Technol , vol.44 , pp. 359-369
    • Yan, H.1    Tian, M.2    Row, K.H.3
  • 22
    • 77952131522 scopus 로고    scopus 로고
    • Preparative separation of glabridin from Glycyrrhiza glabra L. Extracts with macroporous resins
    • Y. Xu, Q. Yuan, and X. Hou Preparative separation of glabridin from Glycyrrhiza glabra L. extracts with macroporous resins Sep Sci Technol 44 2009 3717 3734
    • (2009) Sep Sci Technol , vol.44 , pp. 3717-3734
    • Xu, Y.1    Yuan, Q.2    Hou, X.3
  • 23
    • 84869875123 scopus 로고    scopus 로고
    • Anti-obesity effects of glabridin-rich supercritical carbon dioxide extract of licorice in high-fat-fed obese mice
    • J. Ahn, H. Lee, J. Jang, S. Kim, and T. Ha Anti-obesity effects of glabridin-rich supercritical carbon dioxide extract of licorice in high-fat-fed obese mice Food Chem Toxicol 51 2013 439 445
    • (2013) Food Chem Toxicol , vol.51 , pp. 439-445
    • Ahn, J.1    Lee, H.2    Jang, J.3    Kim, S.4    Ha, T.5
  • 25
    • 80052767882 scopus 로고    scopus 로고
    • An extract of Glycyrrhiza glabra (GutGard) alleviates symptoms of functional dyspepsia: A randomized, double-blind, placebo-controlled study
    • K.R. Raveendra, Jayachandra, V. Srinivasa, K.R. Sushma, J.J. Allan, and K.S. Goudar An extract of Glycyrrhiza glabra (GutGard) alleviates symptoms of functional dyspepsia: a randomized, double-blind, placebo-controlled study Evid Based Complement Alternat Med 2012 2012 1 9
    • (2012) Evid Based Complement Alternat Med , vol.2012 , pp. 1-9
    • Raveendra, K.R.1    Jayachandra2    Srinivasa, V.3    Sushma, K.R.4    Allan, J.J.5    Goudar, K.S.6
  • 26
    • 59849106615 scopus 로고    scopus 로고
    • Simultaneous extraction and separation of liquiritin, glycyrrhizic acid, and glabridin from licorice root with analytical and preparative chromatography
    • M. Tian, H. Yan, and K.H. Row Simultaneous extraction and separation of liquiritin, glycyrrhizic acid, and glabridin from licorice root with analytical and preparative chromatography Biotechnol Bioprocess Eng 13 2009 671 676
    • (2009) Biotechnol Bioprocess Eng , vol.13 , pp. 671-676
    • Tian, M.1    Yan, H.2    Row, K.H.3
  • 28
    • 0030959281 scopus 로고    scopus 로고
    • Antioxidant constituents from licorice roots: Isolation, structure elucidation and antioxidative capacity toward LDL oxidation
    • DOI 10.1016/S0891-5849(97)00089-0, PII S0891584997000890
    • J. Vaya, P.A. Belinky, and M. Aviram Antioxidant constituents from licorice roots: isolation, structure elucidation and antioxidative capacity toward LDL oxidation Free Radic Biol Med 23 1997 302 313 (Pubitemid 27276611)
    • (1997) Free Radical Biology and Medicine , vol.23 , Issue.2 , pp. 302-313
    • Vaya, J.1    Belinky, P.A.2    Aviram, M.3
  • 29
  • 30
    • 42549117011 scopus 로고    scopus 로고
    • Effect of glabridin from Glycyrrhiza glabra on learning and memory in mice
    • DOI 10.1055/s-2008-1034319
    • Y.-M. Cui, M.-Z. Ao, W. Li, and L.-J. Yu Effect of glabridin from Glycyrrhiza glabra on learning and memory in mice Planta Med 74 2008 377 380 (Pubitemid 351578792)
    • (2008) Planta Medica , vol.74 , Issue.4 , pp. 377-380
    • Cui, Y.-M.1    Ao, M.-Z.2    Li, W.3    Yu, L.-J.4
  • 31
    • 0018928560 scopus 로고
    • Antimicrobial agents from higher plants. Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. Var. Typica
    • DOI 10.1021/np50008a004
    • L. Mitscher, Y. Park, and D. Clark Antimicrobial agents from higher plants. Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. var. typica J Nat Prod 1980 259 269 (Pubitemid 10020142)
    • (1980) Journal of Natural Products , vol.43 , Issue.2 , pp. 259-269
    • Mitscher, L.A.1    Park, Y.H.2    Clark, D.3    Beal, J.L.4
  • 32
    • 56749087126 scopus 로고    scopus 로고
    • Preparation technology of isoflavan glabridin from Glycyrrhiza glabra L
    • S. Ma, A. Muhebuli, K. Bahargul, and Q. He Preparation technology of isoflavan glabridin from Glycyrrhiza glabra L Xinjiang Yike Daxue Xuebao 30 2007 692 694
    • (2007) Xinjiang Yike Daxue Xuebao , vol.30 , pp. 692-694
    • Ma, S.1    Muhebuli, A.2    Bahargul, K.3    He, Q.4
  • 33
    • 77952125694 scopus 로고    scopus 로고
    • Preparative purification of the major flavonoid glabridin from licorice roots by solid phase extraction and preparative high performance liquid chromatography
    • J. Lv, H. Liang, Q. Yuan, Y. Xu, and T. Wang Preparative purification of the major flavonoid glabridin from licorice roots by solid phase extraction and preparative high performance liquid chromatography Sep Sci Technol 45 2010 1104 1111
    • (2010) Sep Sci Technol , vol.45 , pp. 1104-1111
    • Lv, J.1    Liang, H.2    Yuan, Q.3    Xu, Y.4    Wang, T.5
  • 39
    • 0031839964 scopus 로고    scopus 로고
    • Structural aspects of the inhibitory effect of glabridin on LDL oxidation
    • DOI 10.1016/S0891-5849(98)00006-9, PII S0891584998000069
    • P.A. Belinky, M. Aviram, S. Mahmood, and J. Vaya Structural aspects of the inhibitory effect of glabridin on LDL oxidation Free Radic Biol Med 24 1998 1419 1429 (Pubitemid 28270343)
    • (1998) Free Radical Biology and Medicine , vol.24 , Issue.9 , pp. 1419-1429
    • Belinky, P.A.1    Aviram, M.2    Mahmood, S.3    Vaya, J.4
  • 40
    • 67649336932 scopus 로고    scopus 로고
    • Synthesis of glabridin derivatives as tyrosinase inhibitors
    • W. Jirawattanapong, E. Saifah, and C. Patarapanich Synthesis of glabridin derivatives as tyrosinase inhibitors Arch Pharm Res 32 2009 647 654
    • (2009) Arch Pharm Res , vol.32 , pp. 647-654
    • Jirawattanapong, W.1    Saifah, E.2    Patarapanich, C.3
  • 42
    • 71749111413 scopus 로고    scopus 로고
    • Absolute configurations of (±) glabridin enantiomers
    • M. Kim, S. Kim, Y. Kim, and J. Han Absolute configurations of (±) glabridin enantiomers Configurations 30 2009 415 418
    • (2009) Configurations , vol.30 , pp. 415-418
    • Kim, M.1    Kim, S.2    Kim, Y.3    Han, J.4
  • 43
    • 33947511161 scopus 로고    scopus 로고
    • Facile and efficient synthesis of (±) glabridin
    • S. Yoo, and K. Nahm Facile and efficient synthesis of (±) glabridin Bull Korean Chem Soc 28 2007 481 484
    • (2007) Bull Korean Chem Soc , vol.28 , pp. 481-484
    • Yoo, S.1    Nahm, K.2
  • 48
    • 0033553495 scopus 로고    scopus 로고
    • Macrophage enrichment with the isoflavan glabridin inhibits NADPH oxidase-induced cell-mediated oxidation of low density lipoprotein
    • M. Rosenblat, P. Belinky, J. Vaya, and R. Levy Macrophage enrichment with the isoflavan glabridin inhibits NADPH oxidase-induced cell-mediated oxidation of low density lipoprotein J Biol Chem 274 1999 13790 13799
    • (1999) J Biol Chem , vol.274 , pp. 13790-13799
    • Rosenblat, M.1    Belinky, P.2    Vaya, J.3    Levy, R.4
  • 54
    • 84867813780 scopus 로고    scopus 로고
    • A validated stability-indicating HPLC method for analysis of glabridin prodrugs in hydrolysis studies
    • W. Jirawattanapong, E. Saifah, and C. Patarapanich A validated stability-indicating HPLC method for analysis of glabridin prodrugs in hydrolysis studies Drug Discov Ther 3 2009 97 103
    • (2009) Drug Discov Ther , vol.3 , pp. 97-103
    • Jirawattanapong, W.1    Saifah, E.2    Patarapanich, C.3
  • 55
    • 84869076090 scopus 로고    scopus 로고
    • Preparing glabridin-in-water nanoemulsions by high pressure homogenization with response surface methodology
    • C.-W. Hsieh, P.-H. Li, I.-C. Lu, and T.-H. Wang Preparing glabridin-in-water nanoemulsions by high pressure homogenization with response surface methodology J Oleo Sci 61 2012 483 489
    • (2012) J Oleo Sci , vol.61 , pp. 483-489
    • Hsieh, C.-W.1    Li, P.-H.2    Lu, I.-C.3    Wang, T.-H.4
  • 56
  • 57
    • 84865458485 scopus 로고    scopus 로고
    • Tyrosinase inhibitor-loaded microsponge drug delivery system: New approach for hyperpigmentation disorders
    • K. Deshmukh, and S.S. Poddar Tyrosinase inhibitor-loaded microsponge drug delivery system: new approach for hyperpigmentation disorders J Microencapsul 29 2012 559 568
    • (2012) J Microencapsul , vol.29 , pp. 559-568
    • Deshmukh, K.1    Poddar, S.S.2
  • 58
    • 84867810628 scopus 로고    scopus 로고
    • Rapid RP-HPLC method for the quantification of glabridin in crude drug and in polyherbal formulation
    • Y. Kamal, and M. Singh Rapid RP-HPLC method for the quantification of glabridin in crude drug and in polyherbal formulation J Chromatogr Sci 50 2012 779 784
    • (2012) J Chromatogr Sci , vol.50 , pp. 779-784
    • Kamal, Y.1    Singh, M.2
  • 61
    • 84864754756 scopus 로고    scopus 로고
    • Prenylated isoflavonoids from plants as selective estrogen receptor modulators (phytoSERMs)
    • R. Simons, H. Gruppen, and T. Bovee Prenylated isoflavonoids from plants as selective estrogen receptor modulators (phytoSERMs) Food Funct 3 2012 810 827
    • (2012) Food Funct , vol.3 , pp. 810-827
    • Simons, R.1    Gruppen, H.2    Bovee, T.3
  • 62
    • 84889888966 scopus 로고    scopus 로고
    • Phytoestrogens and the metabolic syndrome
    • 10.1016/j.jsbmb.2012.12.009
    • A. Jungbauer, and S. Medjakovic Phytoestrogens and the metabolic syndrome J Steroid Biochem Mol Biol 2013 10.1016/j.jsbmb.2012.12.009
    • (2013) J Steroid Biochem Mol Biol
    • Jungbauer, A.1    Medjakovic, S.2
  • 63
    • 0032239708 scopus 로고    scopus 로고
    • The Inhibitory Effect of Glabridin from Licorice Extracts on Melanogenesis and Inflammation
    • T. Yokota, H. Nishio, Y. Kubota, and M. Mizoguchi The inhibitory effect of glabridin from licorice extracts on melanogenesis and inflammation Pigment Cell Res 11 1998 355 361 (Pubitemid 128531532)
    • (1998) Pigment Cell Research , vol.11 , Issue.6 , pp. 355-361
    • Yokota, T.1    Nishio, H.2    Kubota, Y.3    Mizoguchi, M.4
  • 65
    • 75749104978 scopus 로고    scopus 로고
    • Glabridin inhibits Lipopolysaccharide-induced activation of a microglial cell line, BV-2, by blocking NF-kB and AP-1
    • S.H. Park, J.S. Kang, Y.D. Yoon, K. Lee, K. Kim, and K.H. Lee Glabridin inhibits Lipopolysaccharide-induced activation of a microglial cell line, BV-2, by blocking NF-kB and AP-1 Phytother Res 34 2010 29 34
    • (2010) Phytother Res , vol.34 , pp. 29-34
    • Park, S.H.1    Kang, J.S.2    Yoon, Y.D.3    Lee, K.4    Kim, K.5    Lee, K.H.6
  • 66
    • 77957230256 scopus 로고    scopus 로고
    • Inhibition of bone marrow-derived dendritic cell maturation by glabridin
    • J.Y. Kim, J.S. Kang, H.M. Kim, H.S. Ryu, H.S. Kim, and H.K. Lee Inhibition of bone marrow-derived dendritic cell maturation by glabridin Int Immunopharmacol 10 2010 1185 1193
    • (2010) Int Immunopharmacol , vol.10 , pp. 1185-1193
    • Kim, J.Y.1    Kang, J.S.2    Kim, H.M.3    Ryu, H.S.4    Kim, H.S.5    Lee, H.K.6
  • 67
    • 36848998886 scopus 로고    scopus 로고
    • Glabridin, a functional compound of liquorice, attenuates colonic inflammation in mice with dextran sulphate sodium-induced colitis
    • DOI 10.1111/j.1365-2249.2007.03539.x
    • H.-S. Kwon, S.-M. Oh, and J.-K. Kim Glabridin, a functional compound of liquorice, attenuates colonic inflammation in mice with dextran sulphate sodium-induced colitis Clin Exp Immunol 151 2008 165 173 (Pubitemid 350230991)
    • (2008) Clinical and Experimental Immunology , vol.151 , Issue.1 , pp. 165-173
    • Kwon, H.-S.1    Oh, S.-M.2    Kim, J.-K.3
  • 68
    • 14344252815 scopus 로고    scopus 로고
    • Glabridin, an isoflavan from licorice root, inhibits inducible nitric-oxide synthase expression and improves survival of mice in experimental model of septic shock
    • DOI 10.1124/jpet.104.077107
    • J.S. Kang, Y.D. Yoon, I.J. Cho, M.H. Han, C.W. Lee, and S. Park Glabridin, an isoflavan from licorice root, inhibits Inducible nitric-oxide synthase expression and improves survival of mice in experimental model of septic shock J Pharmacol Exp Ther 312 2005 1187 1194 (Pubitemid 40293780)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.312 , Issue.3 , pp. 1187-1194
    • Jong, S.K.1    Yeo, D.Y.2    Ig, J.C.3    Mi, H.H.4    Chang, W.L.5    Park, S.-K.6    Hwan, M.K.7
  • 69
    • 79960236561 scopus 로고    scopus 로고
    • Modulation of lipopolysaccharide-induced pro-inflammatory mediators by an extract of Glycyrrhiza glabra and its phytoconstituents
    • P. Thiyagarajan, C.V. Chandrasekaran, H.B. Deepak, and A. Agarwal Modulation of lipopolysaccharide-induced pro-inflammatory mediators by an extract of Glycyrrhiza glabra and its phytoconstituents Inflammopharmacology 19 2011 235 241
    • (2011) Inflammopharmacology , vol.19 , pp. 235-241
    • Thiyagarajan, P.1    Chandrasekaran, C.V.2    Deepak, H.B.3    Agarwal, A.4
  • 72
    • 0034525341 scopus 로고    scopus 로고
    • Review of human studies on oxidative damage and antioxidant protection related to cardiovascular diseases
    • M. Aviram Review of human studies on oxidative damage and antioxidant protection related to cardiovascular diseases Free Radic Res 33 2000 S85 S97
    • (2000) Free Radic Res , vol.33
    • Aviram, M.1
  • 73
    • 77952966112 scopus 로고    scopus 로고
    • Oxidized LDL: Diversity, patterns of recognition, and pathophysiology
    • I. Levitan Oxidized LDL: diversity, patterns of recognition, and pathophysiology Antioxid Redox Signal 13 2010 39 75
    • (2010) Antioxid Redox Signal , vol.13 , pp. 39-75
    • Levitan, I.1
  • 74
    • 0029100502 scopus 로고
    • Pathogenesis of atherosclerosis
    • E. Falk Pathogenesis of atherosclerosis J Am Coll Cardiol 76 1995 18 23
    • (1995) J Am Coll Cardiol , vol.76 , pp. 18-23
    • Falk, E.1
  • 75
    • 0030793620 scopus 로고    scopus 로고
    • Licorice extract and its major polyphenol glabridin protect low-density lipoprotein against lipid peroxidation: In vitro and ex vivo studies in humans and in atherosclerotic apolipoprotein E-deficient mice
    • B. Fuhrman, S. Buch, J. Vaya, P. a Belinky, R. Coleman, and T. Hayek Licorice extract and its major polyphenol glabridin protect low-density lipoprotein against lipid peroxidation: in vitro and ex vivo studies in humans and in atherosclerotic apolipoprotein E-deficient mice Am J Clin Nutr 66 1997 267 275 (Pubitemid 27360324)
    • (1997) American Journal of Clinical Nutrition , vol.66 , Issue.2 , pp. 267-275
    • Fuhrman, B.1    Buch, S.2    Vaya, J.3    Belinky, P.A.4    Coleman, R.5    Hayek, T.6    Aviram, M.7
  • 76
    • 0032478320 scopus 로고    scopus 로고
    • The antioxidative effects of the isoflavan glabridin on endogenous constituents of LDL during its oxidation
    • DOI 10.1016/S0021-9150(97)00251-7, PII S0021915097002517
    • P.A. Belinky, M. Aviram, B. Fuhrman, M. Rosenblat, and J. Vaya The antioxidative effects of the isoflavan glabridin on endogenous constituents of LDL during its oxidation Atherosclerosis 137 1998 49 61 (Pubitemid 28175376)
    • (1998) Atherosclerosis , vol.137 , Issue.1 , pp. 49-61
    • Belinky, P.A.1    Aviram, M.2    Fuhrman, B.3    Rosenblat, M.4    Vaya, J.5
  • 77
    • 0036259952 scopus 로고    scopus 로고
    • The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9
    • DOI 10.1124/dmd.30.6.709
    • U. Kent, M. Aviram, M. Rosenblat, and P.F. Hollenberg The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9 Drug Metab Dispos 30 2002 709 715 (Pubitemid 34579106)
    • (2002) Drug Metabolism and Disposition , vol.30 , Issue.6 , pp. 709-715
    • Kent, U.M.1    Aviram, M.2    Rosenblat, M.3    Hollenberg, P.F.4
  • 78
    • 68849095967 scopus 로고    scopus 로고
    • Antioxidant effect of polyphenolic glabridin on LDL oxidation
    • E. Carmeli, and Y. Fogelman Antioxidant effect of polyphenolic glabridin on LDL oxidation Toxicol Ind Health 25 2009 321 324
    • (2009) Toxicol Ind Health , vol.25 , pp. 321-324
    • Carmeli, E.1    Fogelman, Y.2
  • 79
    • 65549138006 scopus 로고    scopus 로고
    • Paraoxonases role in the prevention of cardiovascular diseases
    • M. Rosenblat, and M. Aviram Paraoxonases role in the prevention of cardiovascular diseases Biofactors 35 2008 98 104
    • (2008) Biofactors , vol.35 , pp. 98-104
    • Rosenblat, M.1    Aviram, M.2
  • 80
    • 79955539302 scopus 로고    scopus 로고
    • Glabridin, a phytoestrogen from licorice root, up-regulates manganese superoxide dismutase, catalase and paraoxonase 2 under glucose stress
    • I. Yehuda, Z. Madar, A. Szuchman-Sapir, and S. Tamir Glabridin, a phytoestrogen from licorice root, up-regulates manganese superoxide dismutase, catalase and paraoxonase 2 under glucose stress Phytother Res 25 2011 659 667
    • (2011) Phytother Res , vol.25 , pp. 659-667
    • Yehuda, I.1    Madar, Z.2    Szuchman-Sapir, A.3    Tamir, S.4
  • 81
    • 84859618901 scopus 로고    scopus 로고
    • Glabridin protects paraoxonase 1 from linoleic acid hydroperoxide inhibition via specific interaction: A fluorescence-quenching study
    • D. Atrahimovich, J. Vaya, H. Tavori, and S. Khatib Glabridin protects paraoxonase 1 from linoleic acid hydroperoxide inhibition via specific interaction: a fluorescence-quenching study J Agric Food Chem 60 2012 3679 3685
    • (2012) J Agric Food Chem , vol.60 , pp. 3679-3685
    • Atrahimovich, D.1    Vaya, J.2    Tavori, H.3    Khatib, S.4
  • 82
    • 3342934861 scopus 로고    scopus 로고
    • Estrogen-like activity of licorice root constituents: Glabridin and glabrene, in vascular tissues in vitro and in vivo
    • DOI 10.1016/j.jsbmb.2004.04.003, PII S0960076004002171
    • D. Somjen, E. Knoll, J. Vaya, N. Stern, and S. Tamir Estrogen-like activity of licorice root constituents: glabridin and glabrene, in vascular tissues in vitro and in vivo J Steroid Biochem Mol Biol 91 2004 147 155 (Pubitemid 38992809)
    • (2004) Journal of Steroid Biochemistry and Molecular Biology , vol.91 , Issue.3 , pp. 147-155
    • Somjen, D.1    Knoll, E.2    Vaya, J.3    Stern, N.4    Tamir, S.5
  • 83
    • 33644847833 scopus 로고    scopus 로고
    • Glabridin suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-α-stimulated human umbilical vein endothelial cells by blocking sphingosine kinase pathway: Implications of Akt, extracellular signal-regulated kinase, and nuclear factor-κB/Rel signaling pathways
    • DOI 10.1124/mol.105.017442
    • J.S. Kang, Y.D. Yoon, M.H. Han, S. Han, K. Lee, and K.H. Lee Glabridin suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-α-stimulated human umbilical vein endothelial cells by blocking sphingosine kinase pathway: implications of Akt, extracellular signal-regulated Mol Pharmacol 69 2006 941 949 (Pubitemid 43363868)
    • (2006) Molecular Pharmacology , vol.69 , Issue.3 , pp. 941-949
    • Jong, S.K.1    Yeo, D.Y.2    Mi, H.H.3    Han, S.-B.4    Lee, K.5    Ki, H.L.6    Park, S.-K.7    Hwan, M.K.8
  • 84
    • 37049028779 scopus 로고    scopus 로고
    • In vitro and in vivo neuroprotective effect and mechanisms of glabridin, a major active isoflavan from Glycyrrhiza glabra (licorice)
    • DOI 10.1016/j.lfs.2007.10.019, PII S0024320507007795
    • X. Yu, C. Xue, Z. Zhou, C. Li, and Y. Du In vitro and in vivo neuroprotective effect and mechanisms of glabridin, a major active isoflavan from Glycyrrhiza glabra (licorice) Life Sci 82 2008 68 78 (Pubitemid 350251394)
    • (2008) Life Sciences , vol.82 , Issue.1-2 , pp. 68-78
    • Yu, X.-Q.1    Xue, C.C.2    Zhou, Z.-W.3    Li, C.-G.4    Du, Y.-M.5    Liang, J.6    Zhou, S.-F.7
  • 85
    • 84880904636 scopus 로고    scopus 로고
    • Apoptosis in neurodegenerative disease
    • K.A. Roth, and J.J. Shacka Apoptosis in neurodegenerative disease Encycl Neurosci 2009 531 537
    • (2009) Encycl Neurosci , pp. 531-537
    • Roth, K.A.1    Shacka, J.J.2
  • 86
    • 79959253208 scopus 로고    scopus 로고
    • Glabridin as a major active isoflavan from Glycyrrhiza glabra (licorice) reverses learning and memory deficits in diabetic rats
    • P. Hasanein Glabridin as a major active isoflavan from Glycyrrhiza glabra (licorice) reverses learning and memory deficits in diabetic rats Acta Physiol Hung 98 2011 221 230
    • (2011) Acta Physiol Hung , vol.98 , pp. 221-230
    • Hasanein, P.1
  • 88
    • 0038279952 scopus 로고    scopus 로고
    • Inhibition of serotonin re-uptake by licorice constituents
    • DOI 10.1385/JMN:20:2:135
    • R. Ofir, S. Tamir, S. Khatib, and J. Vaya Inhibition of serotonin re-uptake by licorice constituents J Mol Neurosci 20 2003 135 140 (Pubitemid 36693817)
    • (2003) Journal of Molecular Neuroscience , vol.20 , Issue.2 , pp. 135-140
    • Ofir, R.1    Tamir, S.2    Khatib, S.3    Vaya, J.4
  • 89
    • 0026705081 scopus 로고
    • Basic advances in serotonin pharmacology
    • R.W. Fuller Basic advances in serotonin pharmacology J Clin Psychiatry 53 1992 36 45
    • (1992) J Clin Psychiatry , vol.53 , pp. 36-45
    • Fuller, R.W.1
  • 91
    • 0034667496 scopus 로고    scopus 로고
    • Estrogenic and antiproliferative properties of glabridin from licorice in human breast cancer cells
    • S. Tamir, M. Eizenberg, D. Somjen, N. Stern, R. Shelach, and A. Kaye Estrogenic and antiproliferative properties of glabridin from licorice in human breast cancer cells Cancer Res 60 2000 5704 5709
    • (2000) Cancer Res , vol.60 , pp. 5704-5709
    • Tamir, S.1    Eizenberg, M.2    Somjen, D.3    Stern, N.4    Shelach, R.5    Kaye, A.6
  • 93
    • 4444287838 scopus 로고    scopus 로고
    • Estrogenic activity of glabridin and glabrene from licorice roots on human osteoblasts and prepubertal rat skeletal tissues
    • DOI 10.1016/j.jsbmb.2004.04.008, PII S0960076004002870
    • D. Somjen, S. Katzburg, J. Vaya, A.M. Kaye, D. Hendel, and G.H. Posner Estrogenic activity of glabridin and glabrene from licorice roots on human osteoblasts and prepubertal rat skeletal tissues J Steroid Biochem Mol Biol 91 2004 241 246 (Pubitemid 39164607)
    • (2004) Journal of Steroid Biochemistry and Molecular Biology , vol.91 , Issue.4-5 , pp. 241-246
    • Somjen, D.1    Katzburg, S.2    Vaya, J.3    Kaye, A.M.4    Hendel, D.5    Posner, G.H.6    Tamir, S.7
  • 95
    • 21344438903 scopus 로고    scopus 로고
    • The licorice root derived isoflavan glabridin increases the function of osteoblastic MC3T3-E1 cells
    • DOI 10.1016/j.bcp.2005.04.019, PII S0006295205002546
    • E.-M. Choi The licorice root derived isoflavan glabridin increases the function of osteoblastic MC3T3-E1 cells Biochem Pharmacol 70 2005 363 368 (Pubitemid 40905108)
    • (2005) Biochemical Pharmacology , vol.70 , Issue.3 , pp. 363-368
    • Choi, E.-M.1
  • 96
    • 84873111292 scopus 로고    scopus 로고
    • The flavonoid glabridin attenuates 2-deoxy-D-ribose-induced oxidative damage and cellular dysfunction in MC3T3-E1 osteoblastic cells
    • H.-S. Kim, K.S. Suh, A. Ko, D. Sul, D. Choi, and S.K. Lee The flavonoid glabridin attenuates 2-deoxy-D-ribose-induced oxidative damage and cellular dysfunction in MC3T3-E1 osteoblastic cells Int J Mol Med 31 2013 243 251
    • (2013) Int J Mol Med , vol.31 , pp. 243-251
    • Kim, H.-S.1    Suh, K.S.2    Ko, A.3    Sul, D.4    Choi, D.5    Lee, S.K.6
  • 97
    • 79960001386 scopus 로고    scopus 로고
    • Glabridin protects osteoblastic MC3T3-E1 cells against antimycin A induced cytotoxicity
    • E.M. Choi Glabridin protects osteoblastic MC3T3-E1 cells against antimycin A induced cytotoxicity Chem Biol Interact 193 2011 71 78
    • (2011) Chem Biol Interact , vol.193 , pp. 71-78
    • Choi, E.M.1
  • 98
    • 81255127521 scopus 로고    scopus 로고
    • Mutual interaction of special phytoestrogenic compounds, their synthetic carboxy-derivatives and the less-calcemic vitamin D analog activities in human derived female cultured osteoblasts
    • D. Somjen, S. Katzburg, O. Sharon, G.H. Posner, N. Jaccard, and D. Hendel Mutual interaction of special phytoestrogenic compounds, their synthetic carboxy-derivatives and the less-calcemic vitamin D analog activities in human derived female cultured osteoblasts J Steroid Biochem Mol Biol 127 2011 351 357
    • (2011) J Steroid Biochem Mol Biol , vol.127 , pp. 351-357
    • Somjen, D.1    Katzburg, S.2    Sharon, O.3    Posner, G.H.4    Jaccard, N.5    Hendel, D.6
  • 100
    • 83455211711 scopus 로고    scopus 로고
    • New insights into osteoblasts and their role in bone formation: The central role of PI3 kinase
    • A.R. Guntur, and C.J. Rosen New insights into osteoblasts and their role in bone formation: the central role of PI3 kinase J Endocrinol 211 2011 123 130
    • (2011) J Endocrinol , vol.211 , pp. 123-130
    • Guntur, A.R.1    Rosen, C.J.2
  • 101
    • 84855167757 scopus 로고    scopus 로고
    • The inhibitory effect and the molecular mechanism of glabridin on RANKL-induced osteoclastogenesis in RAW264.7 cells
    • H.-S. Kim, K.S. Suh, D. Sul, B.-J. Kim, S.K. Lee, and W.-W. Jung The inhibitory effect and the molecular mechanism of glabridin on RANKL-induced osteoclastogenesis in RAW264.7 cells Int J Mol Med 29 2012 169 177
    • (2012) Int J Mol Med , vol.29 , pp. 169-177
    • Kim, H.-S.1    Suh, K.S.2    Sul, D.3    Kim, B.-J.4    Lee, S.K.5    Jung, W.-W.6
  • 102
    • 79955618001 scopus 로고    scopus 로고
    • AMP-activated protein kinase and metabolic control
    • B. Viollet, and F. Andreelli AMP-activated protein kinase and metabolic control Handb Exp Pharmacol 203 2011 303 330
    • (2011) Handb Exp Pharmacol , vol.203 , pp. 303-330
    • Viollet, B.1    Andreelli, F.2
  • 103
    • 84862493914 scopus 로고    scopus 로고
    • AMP-activated protein kinase: New regulation, new roles?
    • D. Carling, C. Thornton, A. Woods, and M.J. Sanders AMP-activated protein kinase: new regulation, new roles? Biochem J 445 2012 11 27
    • (2012) Biochem J , vol.445 , pp. 11-27
    • Carling, D.1    Thornton, C.2    Woods, A.3    Sanders, M.J.4
  • 104
    • 80054911514 scopus 로고    scopus 로고
    • Forming functional fat: A growing understanding of adipocyte differentiation
    • A.G. Cristancho, and M. a Lazar Forming functional fat: a growing understanding of adipocyte differentiation Nat Rev Mol Cell Biol 12 2011 722 734
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 722-734
    • Cristancho, A.G.1    Lazar M, A.2
  • 106
    • 84862314784 scopus 로고    scopus 로고
    • AMPK activation with glabridin ameliorates adiposity and lipid dysregulation in obesity
    • J.-W. Lee, S.S. Choe, H. Jang, J. Kim, H.W. Jeong, and H. Jo AMPK activation with glabridin ameliorates adiposity and lipid dysregulation in obesity J Lipid Res 53 2012 1277 1286
    • (2012) J Lipid Res , vol.53 , pp. 1277-1286
    • Lee, J.-W.1    Choe, S.S.2    Jang, H.3    Kim, J.4    Jeong, H.W.5    Jo, H.6
  • 108
    • 84875252487 scopus 로고    scopus 로고
    • Hypoglycemic effects of glabridin, a polyphenolic flavonoid from licorice, in an animal model of diabetes mellitus
    • F. Wu, Z. Jin, and J. Jin Hypoglycemic effects of glabridin, a polyphenolic flavonoid from licorice, in an animal model of diabetes mellitus Mol Med Rep 7 2013 1278 1282
    • (2013) Mol Med Rep , vol.7 , pp. 1278-1282
    • Wu, F.1    Jin, Z.2    Jin, J.3
  • 109
    • 79958155978 scopus 로고    scopus 로고
    • Antiobesity and lipid lowering effects of Glycyrrhiza chalcones: Experimental and computational studies
    • R. Birari, S. Gupta, C. Mohan, and K. Bhutani Antiobesity and lipid lowering effects of Glycyrrhiza chalcones: experimental and computational studies Phytomedicine 18 2011 795 801
    • (2011) Phytomedicine , vol.18 , pp. 795-801
    • Birari, R.1    Gupta, S.2    Mohan, C.3    Bhutani, K.4
  • 113
    • 84855213313 scopus 로고    scopus 로고
    • Glabridin inhibits migration, invasion, and angiogenesis of human non-small cell lung cancer A549 cells by inhibiting the FAK/rho signaling pathway
    • Y.-M. Tsai, C.-J. Yang, Y.-L. Hsu, L.-Y. Wu, Y.-C. Tsai, and J.-Y. Hung Glabridin inhibits migration, invasion, and angiogenesis of human non-small cell lung cancer A549 cells by inhibiting the FAK/rho signaling pathway Integr Cancer Ther 10 2011 341 349
    • (2011) Integr Cancer Ther , vol.10 , pp. 341-349
    • Tsai, Y.-M.1    Yang, C.-J.2    Hsu, Y.-L.3    Wu, L.-Y.4    Tsai, Y.-C.5    Hung, J.-Y.6
  • 114
    • 79551529076 scopus 로고    scopus 로고
    • Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway
    • Y.-L. Hsu, L.-Y. Wu, M.-F. Hou, E.-M. Tsai, J.-N. Lee, and H.-L. Liang Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway Mol Nutr Food Res 55 2011 318 327
    • (2011) Mol Nutr Food Res , vol.55 , pp. 318-327
    • Hsu, Y.-L.1    Wu, L.-Y.2    Hou, M.-F.3    Tsai, E.-M.4    Lee, J.-N.5    Liang, H.-L.6
  • 115
    • 49749143424 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phytochemicals
    • T. Nabekura, T. Yamaki, K. Ueno, and S. Kitagawa Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phytochemicals Cancer Chemother Pharmacol 62 2008 867 873
    • (2008) Cancer Chemother Pharmacol , vol.62 , pp. 867-873
    • Nabekura, T.1    Yamaki, T.2    Ueno, K.3    Kitagawa, S.4
  • 116
    • 84859376472 scopus 로고    scopus 로고
    • Molecular pathways: Regulation and therapeutic implications of multidrug resistance
    • K.G. Chen, and B.I. Sikic Molecular pathways: regulation and therapeutic implications of multidrug resistance Clin Cancer Res 18 2012 1863 2869
    • (2012) Clin Cancer Res , vol.18 , pp. 1863-2869
    • Chen, K.G.1    Sikic, B.I.2
  • 117
    • 79960472821 scopus 로고    scopus 로고
    • 18β-glycyrrhetinic acid and glabridin prevent oxidative DNA fragmentation in UVB-irradiated human keratinocyte cultures
    • E. Verrati, T. Rossi, S. Giudice, L. Benassi, G. Bertazzoni, and D. Morini 18β-glycyrrhetinic acid and glabridin prevent oxidative DNA fragmentation in UVB-irradiated human keratinocyte cultures Anticancer Res 31 2011 2209 2216
    • (2011) Anticancer Res , vol.31 , pp. 2209-2216
    • Verrati, E.1    Rossi, T.2    Giudice, S.3    Benassi, L.4    Bertazzoni, G.5    Morini, D.6
  • 118
    • 0344851662 scopus 로고    scopus 로고
    • Preliminary evaluation of antinephritis and radical scavenging activities of glabridin from Glycyrrhiza glabra
    • DOI 10.1016/S0367-326X(03)00164-3
    • T. Fukai, K. Satoh, T. Nomura, and H. Sakagami Preliminary evaluation of antinephritis and radical scavenging activities of glabridin from Glycyrrhiza glabra Fitoterapia 74 2003 624 629 (Pubitemid 37443449)
    • (2003) Fitoterapia , vol.74 , Issue.7-8 , pp. 624-629
    • Fukai, T.1    Satoh, K.2    Nomura, T.3    Sakagami, H.4
  • 119
    • 79955747797 scopus 로고    scopus 로고
    • The melanogenesis and mechanisms of skin-lightening agents - Existing and new approaches
    • J.M. Gillbro, and M.J. Olsson The melanogenesis and mechanisms of skin-lightening agents - existing and new approaches Int J Cosmet Sci 33 2011 210 221
    • (2011) Int J Cosmet Sci , vol.33 , pp. 210-221
    • Gillbro, J.M.1    Olsson, M.J.2
  • 120
    • 84871562095 scopus 로고    scopus 로고
    • Isolation, identification and tyrosinase inhibitory activities of the extractives from Allamanda cathartica
    • K. Yamauchi Isolation, identification and tyrosinase inhibitory activities of the extractives from Allamanda cathartica Nat Resour 02 2011 167 172
    • (2011) Nat Resour , vol.2 , pp. 167-172
    • Yamauchi, K.1
  • 123
    • 0036802679 scopus 로고    scopus 로고
    • Antimicrobial activity of licorice flavonoids against methicillin-resistant Staphylococcus aureus
    • DOI 10.1016/S0367-326X(02)00168-5, PII S0367326X02001685
    • T. Fukai, A. Marumo, K. Kaitou, T. Kanda, S. Terada, and T. Nomura Antimicrobial activity of licorice flavonoids against methicillin-resistant Staphylococcus aureus Fitoterapia 73 2002 536 539 (Pubitemid 35266815)
    • (2002) Fitoterapia , vol.73 , Issue.6 , pp. 536-539
    • Fukai, T.1    Marumo, A.2    Kaitou, K.3    Kanda, T.4    Terada, S.5    Nomura, T.6
  • 124
    • 0033776850 scopus 로고    scopus 로고
    • Phenolic constituents of Licorice. VIII. Structures of glicophenone and glicoisoflavanone, and effects of Licorice phenolics on methicillin-resistant Staphylococcus aureus
    • T. Hatano, Y. Shintani, Y. Aga, S. Shiota, T. Tsuchiya, and T. Yoshida Phenolic constituents of Licorice. VIII. Structures of glicophenone and glicoisoflavanone, and effects of Licorice phenolics on methicillin-resistant Staphylococcus aureus Chem Pharm Bull 48 2000 1286 1292
    • (2000) Chem Pharm Bull , vol.48 , pp. 1286-1292
    • Hatano, T.1    Shintani, Y.2    Aga, Y.3    Shiota, S.4    Tsuchiya, T.5    Yoshida, T.6
  • 125
    • 80054005994 scopus 로고    scopus 로고
    • Effect of licorice compounds licochalcone A, glabridin and glycyrrhizic acid on growth and virulence properties of Candida albicans
    • C. Messier, and D. Grenier Effect of licorice compounds licochalcone A, glabridin and glycyrrhizic acid on growth and virulence properties of Candida albicans Mycoses 54 2011 e801 e806
    • (2011) Mycoses , vol.54
    • Messier, C.1    Grenier, D.2
  • 126
    • 68049098932 scopus 로고    scopus 로고
    • Antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin
    • A. Fatima, V.K. Gupta, S. Luqman, A.S. Negi, J.K. Kumar, and K. Shanker Antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin Phytother Res 1193 2009 1190 1193
    • (2009) Phytother Res , vol.1193 , pp. 1190-1193
    • Fatima, A.1    Gupta, V.K.2    Luqman, S.3    Negi, A.S.4    Kumar, J.K.5    Shanker, K.6
  • 127
    • 84872123486 scopus 로고    scopus 로고
    • In vitro anti-Helicobacter pylori activity of a flavonoid rich extract of Glycyrrhiza glabra and its probable mechanisms of action
    • M.K. Asha, D. Debraj, D. Prashanth, J.R. Edwin, H.S. Srikanth, and N. Muruganantham In vitro anti-Helicobacter pylori activity of a flavonoid rich extract of Glycyrrhiza glabra and its probable mechanisms of action J Ethnopharmacol 145 2013 581 586
    • (2013) J Ethnopharmacol , vol.145 , pp. 581-586
    • Asha, M.K.1    Debraj, D.2    Prashanth, D.3    Edwin, J.R.4    Srikanth, H.S.5    Muruganantham, N.6
  • 132
    • 84866461470 scopus 로고    scopus 로고
    • Analysis and purification of bioactive natural products: The AnaPurNa study
    • G.F. Pauli, S.-N. Chen, J.B. Friesen, J.B. McAlpine, and B.U. Jaki Analysis and purification of bioactive natural products: the AnaPurNa study J Nat Prod 75 2012 1243 1255
    • (2012) J Nat Prod , vol.75 , pp. 1243-1255
    • Pauli, G.F.1    Chen, S.-N.2    Friesen, J.B.3    McAlpine, J.B.4    Jaki, B.U.5
  • 133
    • 0842277242 scopus 로고    scopus 로고
    • Definition of Metabolic Syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition
    • DOI 10.1161/01.CIR.0000111245.75752.C6
    • S.M. Grundy, H.B. Brewer, J.I. Cleeman, S.C. Smith, and C. Lenfant Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition Circulation 109 2004 433 438 (Pubitemid 38133916)
    • (2004) Circulation , vol.109 , Issue.3 , pp. 433-438
    • Grundy, S.M.1    Brewer Jr., H.B.2    Cleeman, J.I.3    Smith Jr., S.C.4    Lenfant, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.