The inhibitory effect and the molecular mechanism of glabridin on RANKL-induced osteoclastogenesis in RAW264.7 cells

International Journal of Molecular Medicine

Volumn 29, Issue 2, 2012, Pages 169-177

  Kim, Hyun Sook ^a   Suh, Kwang Sik ^b   Sul, Donggeun ^c   Kim, Byung J O ^c   Lee, Seung Kwan ^a   Jung, Woon Won ^a  

^a Korea University   (South Korea)

^b Kyung Hee University College of Medicine   (South Korea)

^c Korea University College of Medicine   (South Korea)

Author keywords

Bone resorption; Flavonoid; Glabridin; Osteoclastogenesis; Receptor activator of nuclear factor B ligand; Signaling pathway

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CARBONATE DEHYDRATASE II; CATHEPSIN K; CHLORIDE CHANNEL; CHLORIDE CHANNEL 7; GELATINASE B; GLABRIDIN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN C FOS; PROTEIN KINASE B BETA; STRESS ACTIVATED PROTEIN KINASE 1; T CELL IMMUNE REGULATOR 1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NFAT; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MATURATION; CELL NUCLEUS; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; GENE EXPRESSION; MOUSE; NONHUMAN; ONCOGENE SRC; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; BONE RESORPTION; CARBONIC ANHYDRASE II; CATHEPSIN K; CELL DIFFERENTIATION; CELLS, CULTURED; CHLORIDE CHANNELS; GENE EXPRESSION REGULATION; ISOFLAVONES; MAP KINASE KINASE 7; MATRIX METALLOPROTEINASE 9; MEMBRANE PROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NFATC TRANSCRIPTION FACTORS; OSTEOCLASTS; PHENOLS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOPROTEINS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-FOS; RANK LIGAND; TNF RECEPTOR-ASSOCIATED FACTOR 6; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84855167757     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.822     Document Type: Article

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