Glabridin, an isoflavan from licorice root, inhibits inducible nitric-oxide synthase expression and improves survival of mice in experimental model of septic shock

Journal of Pharmacology and Experimental Therapeutics

Volumn 312, Issue 3, 2005, Pages 1187-1194

  Jong, Soon Kang ^a   Yeo, Dae Yoon ^a   Ig, Jun Cho ^a   Mi, Hwa Han ^a   Chang, Woo Lee ^a   Park, Song Kyu ^a   Hwan, Mook Kim ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

GLABRIDIN; I KAPPA B ALPHA; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOFLAVONE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRATE; NITRITE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR REL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA BINDING; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVITY; FEMALE; GENE ACTIVITY; GENE EXPRESSION; GLYCYRRHIZA; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REPORTER GENE; SEPSIS; SEPTIC SHOCK; SURVIVAL;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; DNA; ENZYME INHIBITORS; FEMALE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOLS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SHOCK, SEPTIC;

EID: 14344252815     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.077107     Document Type: Article

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