Phenolics from Glycyrrhiza glabra roots and their PPAR-γ ligand-binding activity

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 2, 2010, Pages 962-970

  Kuroda, Minpei ^a   Mimaki, Yoshihiro ^a   Honda, Shinichi ^b   Tanaka, Hozumi ^b   Yokota, Shinichi ^b   Mae, Tatsumasa ^b  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b KANEKA CORPORATION   (Japan)

Author keywords

Bioassay guided fractionation; Glycyrrhiza glabra; Phenolics; PPAR ligand binding activity

Indexed keywords

2',3',7 TRIHYDROXY 4' METHOXYISOFLAVAN; 3,4' ,7 TRIHYDROXY 3' PRENYLFLAVANE; 5' FORMYLGLABRIDIN; ECHINATIN; GANCAONIN L; GLABROL; GLABRONE; GLYCYRRHIZA GLABRA EXTRACT; KANZONOL W; LICOFLAVANONE A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHENOL DERIVATIVE; SHINFLAVANONE; SHINPTEROCARPIN; TROGLITAZONE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG ISOLATION; DRUG STRUCTURE; GLYCYRRHIZA GLABRA; SPECTROSCOPY;

ANIMALS; BINDING SITES; CELL LINE; CERCOPITHECUS AETHIOPS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCYRRHIZA; LIGANDS; MOLECULAR STRUCTURE; PHENOLS; PLANT ROOTS; PPAR GAMMA; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

GLYCYRRHIZA; GLYCYRRHIZA GLABRA;

EID: 76449109205     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.11.027     Document Type: Article

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36. The samples were dissolved in DMSO, to which the medium was added to obtain the final concentration of 0.1% (v/v) of DMSO. DMSO was also added to the control wells.