Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway

Molecular Nutrition and Food Research

Volumn 55, Issue 2, 2011, Pages 318-327

  Hsu, Ya Ling ^a   Wu, Ling Yu ^a   Hou, Ming Feng ^b   Tsai, Eing Mei ^a,b   Lee, Jau Nan ^a,b   Liang, Hsin Lin ^c   Jong, Yuh Jyh ^a,b   Hung, Chih Hsing ^b   Kuo, Po Lin ^a,b  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c KAOHSIUNG MUNICIPAL UNITED HOSPITAL   (Taiwan)

Author keywords

Angiogenesis; Breast cancer; Glabridin; Invasion; Migration

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; FOCAL ADHESION KINASE; GLABRIDIN; ISOFLAVONE DERIVATIVE; PHENOL DERIVATIVE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, HUMAN;

ADENOCARCINOMA; ANIMAL; ARTICLE; BREAST TUMOR; CELL CULTURE; CELL MIGRATION; CELL MOTION; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; FEMALE; GLYCYRRHIZA; HUMAN; MOUSE; NUDE MOUSE; PATHOLOGY; PLANT ROOT; RANDOMIZATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; VASCULAR ENDOTHELIUM;

ADENOCARCINOMA; ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MIGRATION ASSAYS; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; FEMALE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GLYCYRRHIZA; HUMANS; ISOFLAVONES; MICE; MICE, NUDE; PHENOLS; PLANT ROOTS; RANDOM ALLOCATION; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

GLYCYRRHIZA; MUS MUSCULUS;

EID: 79551529076     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201000148     Document Type: Article

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