Role of Th17 cells in skin inflammation of allergic contact dermatits

Clinical and Developmental Immunology

Volumn 2013, Issue , 2013, Pages

  Peiser, Matthias ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; AMINO ACID; CARRIER PROTEIN; CD2 ANTIGEN; CD59 ANTIGEN; CELL ADHESION MOLECULE; CRYOPYRIN; EPITOPE; GAMMA INTERFERON; HOMING RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P70; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 21; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 4; LANGERIN; MYELOID DIFFERENTIATION FACTOR 88; PROGRAMMED DEATH 1 LIGAND 1; RETINOIC ACID RECEPTOR GAMMA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; UNINDEXED DRUG;

ADAPTIVE IMMUNITY; ALLERGIC REACTION; ANTIGEN PRESENTING CELL; ARTICLE; ASTHMA; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL TRANSPLANTATION; CONTACT ALLERGY; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; DELAYED HYPERSENSITIVITY; DENDRITIC CELL; DERMATITIS; ECZEMA; HUMAN; IMMUNOLOGICAL SYNAPSE; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSORIASIS; REGULATORY T LYMPHOCYTE; SKIN BIOPSY; T LYMPHOCYTE; TH17 CELL; TH2 CELL; ANIMAL; IMMUNOLOGY; METABOLISM; REVIEW; SKIN ALLERGY;

ANIMALS; DERMATITIS, ALLERGIC CONTACT; HUMANS; TH17 CELLS;

EID: 84884245766     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2013/261037     Document Type: Article

References (97)

1. Landsteiner K., Chase M. W., Studies on the sensitization of animals with simple chemical compounds: iV. Anaphylaxis induced by picryl chloride and 2:4 dinitrochlorobenzene. The Journal of Experimental Medicine 1937 66 337 351
2. Chew A., Maibach H. I., Occupational issues of irritant contact dermatitis. International Archives of Occupational and Environmental Health 2003 76 5 339 346 2-s2.0-0042466546 10.1007/s00420-002-0419-0
3. Nosbaum A., Vocanson M., Rozieres A., Hennino A., Nicolas J., Allergic and irritant contact dermatitis. European Journal of Dermatology 2009 19 4 325 332 2-s2.0-67650901555 10.1684/ejd.2009.0686
4. Nestle F. O., Di Meglio P., Qin J., Nickoloff B. J., Skin immune sentinels in health and disease. Nature Reviews Immunology 2009 9 10 679 691 2-s2.0-70349448402 10.1038/nri2622
5. Lepoittevin J., Metabolism versus chemical transformation or pro- versus prehaptens? Contact Dermatitis 2006 54 2 73 74 2-s2.0-33645082936 10.1111/j.0105-1873.2006.00795.x
6. Kaplan D. H., Igyártó B. Z., Gaspari A. A., Early immune events in the induction of allergic contact dermatitis. Nature Reviews Immunology 2012 12 2 114 124 2-s2.0-84856234422 10.1038/nri3150
7. Igyarto B. Z., Kaplan D. H., The evolving function of Langerhans cells in adaptive skin immunity. Immunology and Cell Biology 2010 88 4 361 365 2-s2.0-77952242565 10.1038/icb.2010.24
8. Romani N., Clausen B. E., Stoitzner P., Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin. Immunological Reviews 2010 234 1 120 141 2-s2.0-77349112874 10.1111/j.0105-2896.2009.00886.x
9. Banchereau J., Steinman R. M., Dendritic cells and the control of immunity. Nature 1998 392 6673 245 252 2-s2.0-0032546352 10.1038/32588
10. Monks C. R. F., Freiberg B. A., Kupfer H., Sciaky N., Kupfer A., Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 1998 395 6697 82 86 2-s2.0-0032480279 10.1038/25764
11. Greenwald R. J., Freeman G. J., Sharpe A. H., The B7 family revisited. Annual Review of Immunology 2005 23 515 548 2-s2.0-17644425689 10.1146/annurev.immunol.23.021704.115611
12. Tang A., Judge T. A., Nickoloff B. J., Turka L. A., Suppression of murine allergic contact dermatitis by CTLA4Ig: tolerance induction of Th2 responses requires additional blockade of CD40-ligand. The Journal of Immunology 1996 157 1 117 125 2-s2.0-0029898878
13. Schwarz A., Beissert S., Grosse-Heitmeyer K., Gunzer M., Bluestone J. A., Grabbe S., Schwarz T., Evidence for functional relevance of CTLA-4 in ultraviolet-radiation- induced tolerance. The Journal of Immunology 2000 165 4 1824 1831 2-s2.0-0034663943
14. Bangert C., Friedl J., Stary G., Stingl G., Kopp T., Immunopathologic features of allergic contact dermatitis in humans: participation of plasmacytoid dendritic cells in the pathogenesis of the disease? Journal of Investigative Dermatology 2003 121 6 1409 1418 2-s2.0-0345732761 10.1111/j.1523-1747.2003. 12623.x
15. Guo J., Stolina M., Bready J. V., Yin S., Horan T., Yoshinaga S. K., Senaldi G., Stimulatory effects of B7-related protein-1 on cellular and humoral immune responses in mice. The Journal of Immunology 2001 166 9 5578 5584 2-s2.0-0035340501
16. Wong S., Tan A. H., Lam K., Functional hierarchy and relative contribution of the CD28/B7 and ICOS/B7-H2 costimulatory pathways to T cell-mediated delayed-type hypersensitivity. Cellular Immunology 2009 256 1-2 64 71 2-s2.0-62249126543 10.1016/j.cellimm.2009.01.009
17. Tsushima F., Iwai H., Otsuki N., Abe M., Hirose S., Yamazaki T., Akiba H., Yagita H., Takahashi Y., Omura K., Okumura K., Azuma M., Preferential contribution of B7-H1 to programmed death-1-mediated regulation of hapten-specific allergic inflammatory responses. European Journal of Immunology 2003 33 10 2773 2782 2-s2.0-0242366612 10.1002/eji.200324084
18. Hee K. K., Guan H., Zu G., Li H., Wu L., Feng X., Elmets C., Fu Y., Xu H., High-level expression of B7-H1 molecules by dendritic cells suppresses the function of activated T cells and desensitizes allergen-primed animals. Journal of Leukocyte Biology 2006 79 4 686 695 2-s2.0-33746416742 10.1189/jlb.0805436
19. Hitzler M., Majdic O., Heine G., Worm M., Ebert G., Luch A., Peiser M., Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy. PLoS ONE 2012 7 e46776
20. Dudda J. C., Lembo A., Bachtanian E., Huehn J., Siewert C., Hamann A., Kremmer E., Förster R., Martin S. F., Dendritic cells govern induction and reprogramming of polarized tissue-selective homing receptor patterns of T cells: important roles for soluble factors and tissue microenvironments. European Journal of Immunology 2005 35 4 1056 1065 2-s2.0-17144398284 10.1002/eji.200425817
21. Kaplan D. H., Kissenpfennig A., Clausen B. E., Insights into Langerhans cell function from Langerhans cell ablation models. European Journal of Immunology 2008 38 9 2369 2376 2-s2.0-55249092998 10.1002/eji.200838397
22. Bennett C. L., van Rijn E., Jung S., Inaba K., Steinman R. M., Kapsenberg M. L., Clausen B. E., Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity. Journal of Cell Biology 2005 169 4 569 576 2-s2.0-22344443257 10.1083/jcb.200501071
23. Kaplan D. H., Jenison M. C., Saeland S., Shlomchik W. D., Shlomchik M. J., Epidermal Langerhans cell-deficient mice develop enhanced contact hypersensitivity. Immunity 2005 23 6 611 620 2-s2.0-28844492624 10.1016/j.immuni.2005.10.008
24. + dendritic cells. Journal of Experimental Medicine 2007 204 13 3147 3156 2-s2.0-37549051226 10.1084/jem.20071966
25. Kissenpfennig A., Henri S., Dubois B., Laplace-Builhé C., Perrin P., Romani N., Tripp C. H., Douillard P., Leserman L., Kaiserlian D., Saeland S., Davoust J., Malissen B., Dynamics and function of langerhans cells in vivo: dermal dendritic cells colonize lymph node areasdistinct from slower migrating langerhans cells. Immunity 2005 22 5 643 654 2-s2.0-21144444056 10.1016/j.immuni.2005.04.004
26. Fukunaga A., Khaskhely N. M., Sreevidya C. S., Byrne S. N., Ullrich S. E., Dermal dendritic cells, and not Langerhans cells, play an essential role in inducing an immune response. The Journal of Immunology 2008 180 5 3057 3064 2-s2.0-49149101883
27. Nakajima S., Igyártó B. Z., Honda T., Egawa G., Otsuka A., Hara-Chikuma M., Watanabe N., Ziegler S. F., Tomura M., Inaba K., Miyachi Y., Kaplan D. H., Kabashima K., Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling. Journal of Allergy and Clinical Immunology 2012 129 4 1048.e6 1055.e6 2-s2.0-84859158015 10.1016/j.jaci.2012.01.063
28. Haley K., Igyártó B. Z., Ortner D., Bobr A., Kashem S., Schenten D., Kaplan D. H., Langerhans cells require MyD88-dependent signals for Candida albicans response but not for contact hypersensitivity or migration. The Journal of Immunology 2012 188 9 4334 4339 2-s2.0-84860318542 10.4049/jimmunol.1102759
29. Grabbe S., Steinbrink K., Steinert M., Luger T. A., Schwarz T., Removal of the majority of epidermal Langerhans cells by topical or systemic steroid application enhances the effector phase of murine contact hypersensitivity. The Journal of Immunology 1995 155 9 4207 4217 2-s2.0-0028824168
30. Kubo A., Nagao K., Yokouchi M., Sasaki H., Amagai M., External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers. Journal of Experimental Medicine 2009 206 13 2937 2946 2-s2.0-73949120263 10.1084/jem.20091527
31. Watanabe H., Gaide O., Pétrilli V., Martinon F., Contassot E., Roques S., Kummer J. A., Tschopp J., French L. E., Activation of the IL-1 β -processing inflammasome is involved in contact hypersensitivity. Journal of Investigative Dermatology 2007 127 8 1956 1963 2-s2.0-34250792190 10.1038/sj.jid.5700819
32. Williams I. R., Ort R. J., Kupper T. S., Keratinocyte expression of B7-1 in transgenic mice amplifies the primary immune response to cutaneous antigens. Proceedings of the National Academy of Sciences of the United States of America 1994 91 26 12780 12784 2-s2.0-0028556917 10.1073/pnas.91.26.12780
33. Ferguson T. A., Dube P., Griffith T. S., Regulation of contact hypersensitivity by interleukin 10. Journal of Experimental Medicine 1994 179 5 1597 1604 2-s2.0-0028226996
34. + T cells lacking IL-17 production. Proceedings of the National Academy of Sciences of the United States of America 2009 106 51 21795 21800 2-s2.0-76049091500 10.1073/pnas.0911472106
35. Duraisingham S. S., Hornig J., Gotch F., Patterson S., TLR-stimulated CD34 stem cell-derived human skin-like and monocyte-derived dendritic cells fail to induce Th17 polarization of naive T cells but do stimulate Th1 and Th17 memory responses. The Journal of Immunology 2009 183 4 2242 2251 2-s2.0-70149107541 10.4049/jimmunol.0900474
36. Medzhitov R., Preston-Hurlburt P., Janeway C. A. Jr., A human homologue of the Drosophila toll protein signals activation of adaptive immunity. Nature 1997 388 6640 394 397 2-s2.0-0030831210 10.1038/41131
37. Takeda K., Akira S., Toll-like receptors. Current Protocols in Immunology 2007 chapter 14 New York, NY, USA Wiley Unit 14. 12
38. Iwasaki A., Medzhitov R., Toll-like receptor control of the adaptive immune responses. Nature Immunology 2004 5 10 987 995 2-s2.0-5444262511 10.1038/ni1112
39. Kadowaki N., Ho S., Antonenko S., De Waal Malefyt R., Kastelein R. A., Bazan F., Liu Y.-J., Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. Journal of Experimental Medicine 2001 194 6 863 869 2-s2.0-0035903288 10.1084/jem.194.6.863
40. Sousa C. R., Toll-like receptors and dendritic cells: for whom the bug tolls. Seminars in Immunology 2004 16 1 27 34 2-s2.0-0742272509 10.1016/j.smim.2003.10.004
41. Schmidt M., Raghavan B., Müller V., Vogl T., Fejer G., Tchaptchet S., Keck S., Kalis C., Nielsen P. J., Galanos C., Roth J., Skerra A., Martin S. F., Freudenberg M. A., Goebeler M., Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel. Nature Immunology 2010 11 9 814 819 2-s2.0-77955886553 10.1038/ni.1919
42. Raghavan B., Martin S. F., Esser P. R., Goebeler M., Schmidt M., Metal allergens nickel and cobalt facilitate TLR4 homodimerization independently of MD2. EMBO Reports 2012 13 1109 1115
43. Sutterwala F. S., Ogura Y., Szczepanik M., Lara-Tejero M., Lichtenberger G. S., Grant E. P., Bertin J., Coyle A. J., Galán J. E., Askenase P. W., Flavell R. A., Critical role for NALP3/CIAS1/cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 2006 24 3 317 327 2-s2.0-33644985564 10.1016/j.immuni.2006.02.004
44. Antonopoulos C., Cumberbatch M., Dearman R. J., Daniel R. J., Kimber I., Groves R. W., Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitization in mice. The Journal of Immunology 2001 166 6 3672 3677 2-s2.0-0035869399
45. 7 results in resistance to contact hypersensitivity. Journal of Experimental Medicine 2010 207 12 2609 2619 2-s2.0-78649414124 10.1084/jem.20092489
46. Gallucci S., Matzinger P., Danger signals: SOS to the immune system. Current Opinion in Immunology 2001 13 1 114 119 2-s2.0-0035139983 10.1016/S0952-7915(00)00191-6
47. Kapsenberg M. L., Dendritic-cell control of pathogen-driven T-cell polarization. Nature Reviews Immunology 2003 3 12 984 993 2-s2.0-0348135024
48. Mosmann T. R., Cherwinski H., Bond M. W., Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. The Journal of Immunology 1986 136 7 2348 2357 2-s2.0-0022640843
49. Iwakura Y., Ishigame H., Saijo S., Nakae S., Functional specialization of interleukin-17 family members. Immunity 2011 34 2 149 162 2-s2.0-79951743212 10.1016/j.immuni.2011.02.012
50. Ye P., Rodriguez F. H., Kanaly S., Stocking K. L., Schurr J., Schwarzenberger P., Oliver P., Huang W., Zhang P., Zhang J., Shellito J. E., Bagby G. J., Nelson S., Charrier K., Peschon J. J., Kolls J. K., Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense. Journal of Experimental Medicine 2001 194 4 519 527 2-s2.0-17944364849 10.1084/jem.194.4.519
51. Infante-Duarte C., Horton H. F., Byrne M. C., Kamradt T., Microbial lipopeptides induce the production of IL-17 in Th cells. The Journal of Immunology 2000 165 11 6107 6115 2-s2.0-0034541221
52. Huang W., Na L., Fidel P. L., Schwarzenberger P., Requirement of interleukin-17A for systemic anti- Candida albicans host defense in mice. Journal of Infectious Diseases 2004 190 3 624 631 2-s2.0-3242814586 10.1086/422329
53. Cua D. J., Sherlock J., Chen Y., Murphy C. A., Joyce B., Seymour B., Lucian L., To W., Kwan S., Churakova T., Zurawski S., Wiekowski M., Lira S. A., Gorman D., Kastelein R. A., Sedgwick J. D., Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003 421 6924 744 748 2-s2.0-0037434789 10.1038/nature01355
54. Sato K., Suematsu A., Okamoto K., Yamaguchi A., Morishita Y., Kadono Y., Tanaka S., Kodama T., Akira S., Iwakura Y., Cua D. J., Takayanagi H., Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. Journal of Experimental Medicine 2006 203 12 2673 2682 2-s2.0-33751521013 10.1084/jem.20061775
55. Yen D., Cheung J., Scheerens H., Poulet F., McClanahan T., Mckenzie B., Kleinschek M. A., Owyang A., Mattson J., Blumenschein W., Murphy E., Sathe M., Cua D. J., Kastelein R. A., Rennick D., IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. The Journal of Clinical Investigation 2006 116 5 1310 1316 2-s2.0-33646397611 10.1172/JCI21404
56. Hue S., Ahern P., Buonocore S., Kullberg M. C., Cua D. J., McKenzie B. S., Powrie F., Maloy K. J., Interleukin-23 drives innate and T cell-mediated intestinal inflammation. Journal of Experimental Medicine 2006 203 11 2473 2483 2-s2.0-33750505009 10.1084/jem.20061099
57. Miossec P., Korn T., Kuchroo V. K., Interleukin-17 and type 17 helper T cells. The New England Journal of Medicine 2009 361 9 888 898 2-s2.0-69349093225 10.1056/NEJMra0707449
58. Awasthi A., Kuchroo V. K., Th17 cells: from precursors to players in inflammation and infection. International Immunology 2009 21 5 489 498 2-s2.0-65549152333 10.1093/intimm/dxp021
59. Yosef N., Shalek A. K., Gaublomme J. T., Jin H., Lee Y., Awasthi A., Wu C., Karwacz K., Xiao S., Jorgolli M., Gennert D., Satija R., Shakya A., Lu D. Y., Trombetta J. J., Pillai M. R., Ratcliffe P. J., Coleman M. L., Bix M., Tantin D., Park H., Kuchroo V. K., Regev A., Dynamic regulatory network controlling TH17 cell differentiation. Nature 2013 496 461 468
60. Manel N., Unutmaz D., Littman D. R., The differentiation of human TH-17 cells requires transforming growth factor- β and induction of the nuclear receptor ROR γ t. Nature Immunology 2008 9 6 641 649 2-s2.0-44049104564 10.1038/ni.1610
61. + T cells. European Journal of Immunology 2009 39 6 1480 1493 2-s2.0-67649525188 10.1002/eji.200838908
62. Burgler S., Ouaked N., Bassin C., Basinski T. M., Mantel P., Siegmund K., Meyer N., Akdis C. A., Schmidt-Weber C. B., Differentiation and functional analysis of human TH17 cells. Journal of Allergy and Clinical Immunology 2009 123 3 588.e7 595.e7 2-s2.0-61549130932 10.1016/j.jaci.2008.12.017
63. + T cell precursor. Journal of Experimental Medicine 2008 205 8 1903 1916 2-s2.0-49249135394 10.1084/jem.20080397
64. Acosta-Rodriguez E. V., Rivino L., Geginat J., Jarrossay D., Gattorno M., Lanzavecchia A., Sallusto F., Napolitani G., Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nature Immunology 2007 8 6 639 646 2-s2.0-34249079176 10.1038/ni1467
65. - phenotype. The Journal of Immunology 2007 178 12 7525 7529 2-s2.0-34250196774
66. Obermajer N., Wong J. L., Edwards R. P., Chen K., Scott M., Khader S., Kolls J. K., Odunsi K., Billiar T. R., Kalinski P., Induction and stability of human Th17 cells require endogenous NOS2 and cGMP-dependent NO signaling. The Journal of Experimental Medicine 2013 210 1433 1445
67. Santarlasci V., Maggi L., Capone M., Querci V., Beltrame L., Cavalieri D., D'Aiuto E., Cimaz R., Nebbioso A., Liotta F., De Palma R., Maggi E., Cosmi L., Romagnani S., Annunziato F., Rarity of human T helper 17 cells is due to retinoic acid orphan receptor-dependent mechanisms that limit their expansion. Immunity 2012 36 2 201 214 2-s2.0-84857444826 10.1016/j.immuni.2011.12.013
68. Eyerich S., Eyerich K., Cavani A., Schmidt-Weber C., IL-17 and IL-22: siblings, not twins. Trends in Immunology 2010 31 9 354 361 2-s2.0-77956181347 10.1016/j.it.2010.06.004
69. Aliahmadi E., Gramlich R., Grützkau A., Hitzler M., Krüger M., Baumgrass R., Schreiner M., Wittig B., Wanner R., Peiser M., TLR2-activated human langerhans cells promote Th17 polarization via IL-1 β TGF- β and IL-23. European Journal of Immunology 2009 39 5 1221 1230 2-s2.0-67649910766 10.1002/eji.200838742
70. Eyerich K., Pennino D., Scarponi C., Foerster S., Nasorri F., Behrendt H., Ring J., Traidl-Hoffmann C., Albanesi C., Cavani A., IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. Journal of Allergy and Clinical Immunology 2009 123 1 59.e4 66.e4 2-s2.0-58149131262 10.1016/j.jaci.2008.10.031
71. Niebuhr M., Gathmann M., Scharonow H., Mamerow D., Mommert S., Balaji H., Werfel T., Staphylococcal alpha-toxin is a strong inducer of interleukin-17 in humans. Infection and Immunity 2011 79 4 1615 1622 2-s2.0-79953325936 10.1128/IAI.00958-10
72. Nakae S., Komiyama Y., Nambu A., Sudo K., Iwase M., Homma I., Sekikawa K., Asano M., Iwakura Y., Antigen-specific T cell sensitization is impaired in Il-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 2002 17 3 375 387 2-s2.0-0036754255 10.1016/S1074-7613(02) 00391-6
73. Larsen J. M., Bonefeld C. M., Poulsen S. S., Geisler C., Skov L., IL-23 and TH17-mediated inflammation in human allergic contact dermatitis. Journal of Allergy and Clinical Immunology 2009 123 2 486.e1 492.e1 2-s2.0-59449097711 10.1016/j.jaci.2008.09.036
74. Cavani A., Pennino D., Eyerich K., Th17 and Th22 in skin allergy. Chemical Immunology and Allergy 2012 96 39 44 2-s2.0-84859199680 10.1159/000331870
75. Pennino D., Eyerich K., Scarponi C., Carbone T., Eyerich S., Nasorri F., Garcovich S., Traidl-Hoffmann C., Albanesi C., Cavani A., IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes. The Journal of Immunology 2010 184 9 4880 4888 2-s2.0-77954488224 10.4049/jimmunol.0901767
76. Eyerich S., Eyerich K., Pennino D., Carbone T., Nasorri F., Pallotta S., Cianfarani F., Odorisio T., Traidl-Hoffmann C., Behrendt H., Durham S. R., Schmidt-Weber C. B., Cavani A., Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. The Journal of Clinical Investigation 2009 119 12 3573 3585 2-s2.0-72849131815 10.1172/JCI40202
77. Albanesi C., Cavani A., Girolomoni G., IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN- γ and TNF- α The Journal of Immunology 1999 162 1 494 502 2-s2.0-0032939560
78. Eyerich S., Onken A. T., Weidinger S., Franke A., Nasorri F., Pennino D., Grosber M., Pfab F., Schmidt-Weber C. B., Mempel M., Hein R., Ring J., Cavani A., Eyerich K., Mutual antagonism of T cells causing psoriasis and atopic eczema. The New England Journal of Medicine 2011 365 3 231 238 2-s2.0-79960578839
79. Zhao Y., Balato A., Fishelevich R., Chapoval A., Mann D. L., Gaspari A. A., Th17/Tc17 infiltration and associated cytokine gene expression in elicitation phase of allergic contact dermatitis. British Journal of Dermatology 2009 161 6 1301 1306 2-s2.0-72649083292 10.1111/j.1365-2133.2009.09400.x
80. Yao C., Sakata D., Esaki Y., Li Y., Matsuoka T., Kuroiwa K., Sugimoto Y., Narumiya S., Prostaglandin E2-EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion. Nature Medicine 2009 15 6 633 640 2-s2.0-67349127266 10.1038/nm.1968
81. Choi J. K., Oh H. M., Lee S., Park J. W., Khang D., Lee S. W., Lee W. S., Rho M. C., Kim S. H., Oleanolic acid acetate inhibits atopic dermatitis and allergic contact dermatitis in a murine model. Toxicology and Applied Pharmacology 2013 269 72 80
82. Laan M., Cui Z., Hoshino H., Lötvall J., Sjöstrand M., Gruenert D. C., Skoogh B., Lindén A., Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways. The Journal of Immunology 1999 162 4 2347 2352 2-s2.0-0033557728
83. Bellini A., Marini M. A., Bianchetti L., Barczyk M., Schmidt M., Mattoli S., Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients. Mucosal Immunology 2012 5 2 140 149 2-s2.0-84857215266 10.1038/mi.2011.60
84. Park H., Li Z., Yang X. O., Chang S. H., Nurieva R., Wang Y., Wang Y., Hood L., Zhu Z., Tian Q., Dong C., A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nature Immunology 2005 6 11 1133 1141 2-s2.0-27544465354 10.1038/ni1261
85. + T cells exacerbates T cell-dependent inflammation. The Journal of Immunology 2013 190 997 1007
86. Anthoni M., Fyhrquist-Vanni N., Wolff H., Alenius H., Lauerma A., Transforming growth factor- β /Smad3 signalling regulates inflammatory responses in a murine model of contact hypersensitivity. British Journal of Dermatology 2008 159 3 546 554 2-s2.0-49749089366 10.1111/j.1365-2133.2008. 08696.x
87. Martín P., Gómez M., Lamana A., Marín A. M., Cortés J. R., Ramírez-Huesca M., Barreiro O., López-Romero P., Gutiérrez-Vázquez C., De La Fuente H., Cruz-Adalia A., Sánchez-Madrid F., The leukocyte activation antigen CD69 limits allergic asthma and skin contact hypersensitivity. Journal of Allergy and Clinical Immunology 2010 126 2 355.e3 365.e3 2-s2.0-77955920583 10.1016/j.jaci.2010.05. 010
88. Park S. Y., Gupta D., Kim C. H., Dziarski R., Differential effects of peptidoglycan recognition proteins on experimental atopic and contact dermatitis mediated by Treg and Th17 cells. PLoS ONE 2011 6 9 2-s2.0-80052868538 10.1371/journal.pone.0024961 e24961
89. + IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses. The Journal of Immunology 2006 177 10 6852 6858 2-s2.0-33750815930
90. Kish D. D., Li X., Fairchild R. L., CD8 T cells producing IL-17 and IFN- γ initiate the innate immune response required for responses to antigen skin challenge. The Journal of Immunology 2009 182 10 5949 5959 2-s2.0-74049159215 10.4049/jimmunol.0802830
91. Kish D. D., Volokh N., Baldwin W. M. III, Fairchild R. L., Hapten application to the skin induces an inflammatory program directing hapten-primed effector CD8 T cell interaction with hapten-presenting endothelial cells. The Journal of Immunology 2011 186 4 2117 2126 2-s2.0-79951847404 10.4049/jimmunol.1002337
92. Kish D. D., Gorbachev A. V., Fairchild R. L., IL-1 receptor signaling is required at multiple stages of sensitization and elicitation of the contact hypersensitivity response. The Journal of Immunology 2012 188 4 1761 1771 2-s2.0-84856939971 10.4049/jimmunol.1100928
93. Vocanson M., Rozieres A., Hennino A., Poyet G., Gaillard V., Renaudineau S., Achachi A., Benetiere J., Kaiserlian D., Dubois B., Nicolas J., Inducible costimulator (ICOS) is a marker for highly suppressive antigen-specific T cells sharing features of TH17/TH1 and regulatory T cells. Journal of Allergy and Clinical Immunology 2010 126 2 280.e7 289.e7 2-s2.0-77955925040 10.1016/j.jaci.2010.05.022
94. + T cells, respectively, mediate and regulate contact sensitivity to dinitrofluorobenzene. European Journal of Immunology 1995 25 11 3006 3010 2-s2.0-0028865773 10.1002/eji.1830251103
95. Cua D. J., Tato C. M., Innate IL-17-producing cells: the sentinels of the immune system. Nature Reviews Immunology 2010 10 7 479 489 2-s2.0-77954143695 10.1038/nri2800
96. Fischer-Stabauer M., Boehner A., Eyerich S., Carbone T., Traidl-Hoffmann C., Schmidt-Weber C. B., Cavani A., Ring J., Hein R., Eyerich K., Differential in situ expression of IL-17 in skin diseases. European Journal of Dermatology 2012 22 781 784
97. Nosbaum A., Rozieres A., Balme B., Goujon C., Nicolas J. F., Berard F., Blocking T helper 1/T helper 17 pathways has no effect on patch testing. Contact Dermatitis 2013 68 58 59