메뉴 건너뛰기




Volumn 106, Issue 51, 2009, Pages 21795-21800

Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production

Author keywords

Dermal dendritic cells; Skin; Th22

Indexed keywords

CELL PROTEIN; CELL PROTEIN BDCA1; GAMMA INTERFERON; GLYCOPROTEIN P 15095; HLA DR ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 4; LANGERIN; UNCLASSIFIED DRUG;

EID: 76049091500     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0911472106     Document Type: Article
Times cited : (219)

References (38)
  • 1
    • 41549135632 scopus 로고    scopus 로고
    • The biological functions of T helper 17 cell effector cytokines in inflammation
    • Ouyang W, Kolls JK, Zheng Y (2008) The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 28:454-467.
    • (2008) Immunity , vol.28 , pp. 454-467
    • Ouyang, W.1    Kolls, J.K.2    Zheng, Y.3
  • 2
    • 64049111041 scopus 로고    scopus 로고
    • Cytokine mediators of Th17 function
    • Spolski R, Leonard WJ (2009) Cytokine mediators of Th17 function. Eur J Immunol 39:658-661.
    • (2009) Eur J Immunol , vol.39 , pp. 658-661
    • Spolski, R.1    Leonard, W.J.2
  • 3
    • 59749095603 scopus 로고    scopus 로고
    • IL-22 and inflammation: Leukin' through a glass onion
    • Zenewicz LA, Flavell RA (2008) IL-22 and inflammation: Leukin' through a glass onion. Eur J Immunol 38:3265-3268.
    • (2008) Eur J Immunol , vol.38 , pp. 3265-3268
    • Zenewicz, L.A.1    Flavell, R.A.2
  • 4
    • 2142659288 scopus 로고    scopus 로고
    • IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues
    • Gurney AL (2004) IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues. Int Immunopharmacol 4:669-677.
    • (2004) Int Immunopharmacol , vol.4 , pp. 669-677
    • Gurney, A.L.1
  • 5
    • 0036604122 scopus 로고    scopus 로고
    • Immune cells as sources and targets of the IL-10 family members?
    • Wolk K, Kunz S, Asadullah K, Sabat R (2002) Immune cells as sources and targets of the IL-10 family members? J Immunol 168:5397-5402.
    • (2002) J Immunol , vol.168 , pp. 5397-5402
    • Wolk, K.1    Kunz, S.2    Asadullah, K.3    Sabat, R.4
  • 6
    • 67649161002 scopus 로고    scopus 로고
    • IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells
    • Nograles KE, et al. (2009) IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells. J Allergy Clin Immunol 123:1244-1252.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 1244-1252
    • Nograles, K.E.1
  • 7
    • 33846906224 scopus 로고    scopus 로고
    • Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
    • Zheng Y, et al. (2007) Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 445:648-651.
    • (2007) Nature , vol.445 , pp. 648-651
    • Zheng, Y.1
  • 8
    • 59649099774 scopus 로고    scopus 로고
    • A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
    • Cella M, et al. (2009) A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity. Nature 457:722-725.
    • (2009) Nature , vol.457 , pp. 722-725
    • Cella, M.1
  • 9
    • 57449090428 scopus 로고    scopus 로고
    • Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease
    • Zenewicz LA, et al. (2008) Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease. Immunity 29:947-957.
    • (2008) Immunity , vol.29 , pp. 947-957
    • Zenewicz, L.A.1
  • 10
    • 40049083827 scopus 로고    scopus 로고
    • Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
    • Zheng Y, et al. (2008) Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nat Med 14:282-289.
    • (2008) Nat Med , vol.14 , pp. 282-289
    • Zheng, Y.1
  • 11
    • 33749983749 scopus 로고    scopus 로고
    • Interleukin-22: A novel T- and NK-cell derived cytokine that regulates the biology of tissue cells
    • Wolk K, Sabat R (2006) Interleukin-22: A novel T- and NK-cell derived cytokine that regulates the biology of tissue cells. Cytokine Growth Factor Rev 17:367-380.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 367-380
    • Wolk, K.1    Sabat, R.2
  • 12
    • 14844342604 scopus 로고    scopus 로고
    • IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes
    • Boniface K, et al. (2005) IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes. J Immunol 174:3695-3702.
    • (2005) J Immunol , vol.174 , pp. 3695-3702
    • Boniface, K.1
  • 13
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • Liang SC, et al. (2006) Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 203:2271-2279.
    • (2006) J Exp Med , vol.203 , pp. 2271-2279
    • Liang, S.C.1
  • 14
    • 33646552450 scopus 로고    scopus 로고
    • IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes:Apotential role in psoriasis
    • Wolk K, et al. (2006) IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes:Apotential role in psoriasis. Eur J Immunol 36:1309-1323.
    • (2006) Eur J Immunol , vol.36 , pp. 1309-1323
    • Wolk, K.1
  • 15
    • 54249130813 scopus 로고    scopus 로고
    • Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways
    • Nograles KE, et al. (2008) Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways. Br J Dermatol 159:1092-1102.
    • (2008) Br J Dermatol , vol.159 , pp. 1092-1102
    • Nograles, K.E.1
  • 16
    • 33846940253 scopus 로고    scopus 로고
    • Sa SM, et al. (2007) The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J Immunol 178:2229-2240.
    • Sa SM, et al. (2007) The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J Immunol 178:2229-2240.
  • 17
    • 36048953799 scopus 로고    scopus 로고
    • A role for T cell-derived interleukin 22 in psoriatic skin inflammation
    • Boniface K, et al. (2007) A role for T cell-derived interleukin 22 in psoriatic skin inflammation. Clin Exp Immunol 150:407-415.
    • (2007) Clin Exp Immunol , vol.150 , pp. 407-415
    • Boniface, K.1
  • 18
    • 38849187386 scopus 로고    scopus 로고
    • IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation
    • Ma HL, et al. (2008) IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. J Clin Invest 118:597-607.
    • (2008) J Clin Invest , vol.118 , pp. 597-607
    • Ma, H.L.1
  • 19
    • 67649562339 scopus 로고    scopus 로고
    • Memory IL-22-producing CD4+ T cells specific for Candida albicans are present in humans
    • Liu Y, et al. (2009) Memory IL-22-producing CD4+ T cells specific for Candida albicans are present in humans. Eur J Immunol 39:1472-1479.
    • (2009) Eur J Immunol , vol.39 , pp. 1472-1479
    • Liu, Y.1
  • 20
    • 58149131262 scopus 로고    scopus 로고
    • IL-17 in atopic eczema: Linking allergen-specific adaptive and microbial-triggered innate immune response
    • Eyerich K, et al. (2009) IL-17 in atopic eczema: Linking allergen-specific adaptive and microbial-triggered innate immune response. J Allergy Clin Immunol 123:59-66.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 59-66
    • Eyerich, K.1
  • 21
    • 67651154105 scopus 로고    scopus 로고
    • Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
    • Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F (2009) Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol 10:857-863.
    • (2009) Nat Immunol , vol.10 , pp. 857-863
    • Duhen, T.1    Geiger, R.2    Jarrossay, D.3    Lanzavecchia, A.4    Sallusto, F.5
  • 22
    • 67651171182 scopus 로고    scopus 로고
    • Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells
    • SpitsH
    • Trifari S, Kaplan CD, Tran EH, Crellin NK, SpitsH(2009) Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat Immunol 10:864-871.
    • (2009) Nat Immunol , vol.10 , pp. 864-871
    • Trifari, S.1    Kaplan, C.D.2    Tran, E.H.3    Crellin, N.K.4
  • 23
    • 56749152272 scopus 로고    scopus 로고
    • Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells
    • CollinM
    • Merad M, Ginhoux F, CollinM(2008) Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells. Nat Rev Immunol 8:935-947.
    • (2008) Nat Rev Immunol , vol.8 , pp. 935-947
    • Merad, M.1    Ginhoux, F.2
  • 24
    • 34848816502 scopus 로고    scopus 로고
    • Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages
    • Zaba LC, Fuentes-Duculan J, Steinman RM, Krueger JG, Lowes MA (2007) Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages. J Clin Invest 117:2517-2525.
    • (2007) J Clin Invest , vol.117 , pp. 2517-2525
    • Zaba, L.C.1    Fuentes-Duculan, J.2    Steinman, R.M.3    Krueger, J.G.4    Lowes, M.A.5
  • 25
    • 58549114666 scopus 로고    scopus 로고
    • Resident and " inflammatory" dendritic cells in human skin
    • Zaba LC, Krueger JG, Lowes MA (2009) Resident and " inflammatory" dendritic cells in human skin. J Invest Dermatol 129:302-308.
    • (2009) J Invest Dermatol , vol.129 , pp. 302-308
    • Zaba, L.C.1    Krueger, J.G.2    Lowes, M.A.3
  • 26
    • 51349093240 scopus 로고    scopus 로고
    • Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells
    • Klechevsky E, et al. (2008) Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells. Immunity 29:497-510.
    • (2008) Immunity , vol.29 , pp. 497-510
    • Klechevsky, E.1
  • 27
    • 29144470356 scopus 로고    scopus 로고
    • CD4+ T cell responses elicited by different subsets of human skin migratory dendritic cells
    • Morelli AE, et al. (2005) CD4+ T cell responses elicited by different subsets of human skin migratory dendritic cells. J Immunol 175:7905-7915.
    • (2005) J Immunol , vol.175 , pp. 7905-7915
    • Morelli, A.E.1
  • 28
    • 60549093645 scopus 로고    scopus 로고
    • Differential capability of human cutaneous dendritic cell subsets to initiate Th17 responses
    • Mathers AR, et al. (2009) Differential capability of human cutaneous dendritic cell subsets to initiate Th17 responses. J Immunol 182:921-933.
    • (2009) J Immunol , vol.182 , pp. 921-933
    • Mathers, A.R.1
  • 29
    • 58149331211 scopus 로고    scopus 로고
    • Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells
    • Zaba LC, et al. (2009) Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells. J Invest Dermatol 129:79-88.
    • (2009) J Invest Dermatol , vol.129 , pp. 79-88
    • Zaba, L.C.1
  • 30
    • 10144260007 scopus 로고    scopus 로고
    • CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GMCSF+TNF alpha
    • Caux C, et al. (1996) CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GMCSF+TNF alpha. J Exp Med 184:695-706.
    • (1996) J Exp Med , vol.184 , pp. 695-706
    • Caux, C.1
  • 31
    • 0026446156 scopus 로고
    • GM-CSF and TNF-alpha cooperate in the generation of dendritic Langerhans cells
    • Caux C, Dezutter-Dambuyant C, Schmitt D, Banchereau J (1992) GM-CSF and TNF-alpha cooperate in the generation of dendritic Langerhans cells. Nature 360:258-261.
    • (1992) Nature , vol.360 , pp. 258-261
    • Caux, C.1    Dezutter-Dambuyant, C.2    Schmitt, D.3    Banchereau, J.4
  • 32
    • 33751120140 scopus 로고    scopus 로고
    • Expression and regulation of IL-22 in the IL-17-producing CD4+T lymphocytes
    • Chung Y, et al. (2006) Expression and regulation of IL-22 in the IL-17-producing CD4+T lymphocytes. Cell Res 16:902-907.
    • (2006) Cell Res , vol.16 , pp. 902-907
    • Chung, Y.1
  • 33
    • 51349164784 scopus 로고    scopus 로고
    • In vivo induction of immune responses to pathogens by conventional dendritic cells
    • Lopez-Bravo M, Ardavin C (2008) In vivo induction of immune responses to pathogens by conventional dendritic cells. Immunity 29:343-351.
    • (2008) Immunity , vol.29 , pp. 343-351
    • Lopez-Bravo, M.1    Ardavin, C.2
  • 34
    • 70449479858 scopus 로고    scopus 로고
    • Multiparametric analysis of cytokine-driven human Th17 differentiation reveals a differential regulation of IL-17 and IL-22 production
    • Volpe E, et al. (2009) Multiparametric analysis of cytokine-driven human Th17 differentiation reveals a differential regulation of IL-17 and IL-22 production. Blood 114:3610-3614.
    • (2009) Blood , vol.114 , pp. 3610-3614
    • Volpe, E.1
  • 35
    • 37549011317 scopus 로고    scopus 로고
    • Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses
    • Zaba LC, et al. (2007) Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses. J Exp Med 204:3183-3194.
    • (2007) J Exp Med , vol.204 , pp. 3183-3194
    • Zaba, L.C.1
  • 36
    • 67349128168 scopus 로고    scopus 로고
    • Cytokine-producing dendritic cells in the pathogenesis of inflammatory skin diseases
    • Johnson-Huang LM, McNutt NS, Krueger JG, Lowes MA (2009) Cytokine-producing dendritic cells in the pathogenesis of inflammatory skin diseases. J Clin Immunol 29:247-256.
    • (2009) J Clin Immunol , vol.29 , pp. 247-256
    • Johnson-Huang, L.M.1    McNutt, N.S.2    Krueger, J.G.3    Lowes, M.A.4
  • 37
    • 34247532495 scopus 로고    scopus 로고
    • Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis
    • Guttman-Yassky E, et al. (2007) Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis. J Allergy Clin Immunol 119:1210-1217.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 1210-1217
    • Guttman-Yassky, E.1
  • 38
    • 0034023485 scopus 로고    scopus 로고
    • Mature dendritic cells boost functionally superior CD8(+) T-cell in humans without foreign helper epitopes
    • Dhodapkar MV, Krasovsky J, Steinman RM, Bhardwaj N (2000) Mature dendritic cells boost functionally superior CD8(+) T-cell in humans without foreign helper epitopes. J Clin Invest 105:R9-R14.
    • (2000) J Clin Invest , vol.105
    • Dhodapkar, M.V.1    Krasovsky, J.2    Steinman, R.M.3    Bhardwaj, N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.