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Volumn 159, Issue 3, 2008, Pages 546-554

Transforming growth factor-β/Smad3 signalling regulates inflammatory responses in a murine model of contact hypersensitivity

Author keywords

Chemokine; Contact hypersensitivity; Cytokine; Murine model; Smad3; Transforming growth factor

Indexed keywords

CXCL9 CHEMOKINE; EOTAXIN 2; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; OXAZOLONE; SMAD3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 49749089366     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2008.08696.x     Document Type: Article
Times cited : (33)

References (49)
  • 1
    • 0345293274 scopus 로고    scopus 로고
    • Quality of life in patients with allergic contact dermatitis
    • Kadyk DL, McCarter K, Achen F et al. Quality of life in patients with allergic contact dermatitis. J Am Acad Dermatol 2003 49 : 1037 48.
    • (2003) J Am Acad Dermatol , vol.49 , pp. 1037-48
    • Kadyk, D.L.1    McCarter, K.2    Achen, F.3
  • 2
    • 0034689032 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 6 is essential in the induction of contact hypersensitivity
    • Yokozeki H, Ghoreishi M, Takagawa S et al. Signal transducer and activator of transcription 6 is essential in the induction of contact hypersensitivity. J Exp Med 2000 191 : 995 1004.
    • (2000) J Exp Med , vol.191 , pp. 995-1004
    • Yokozeki, H.1    Ghoreishi, M.2    Takagawa, S.3
  • 3
    • 0023269443 scopus 로고
    • Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones
    • Cher DJ, Mosmann TR. Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones. J Immunol 1987 138 : 3688 94.
    • (1987) J Immunol , vol.138 , pp. 3688-94
    • Cher, D.J.1    Mosmann, T.R.2
  • 5
    • 0034925388 scopus 로고    scopus 로고
    • Effector and regulatory T cells in allergic contact dermatitis
    • Cavani A, Albanesi C, Traidl C et al. Effector and regulatory T cells in allergic contact dermatitis. Trends Immunol 2001 22 : 118 20.
    • (2001) Trends Immunol , vol.22 , pp. 118-20
    • Cavani, A.1    Albanesi, C.2    Traidl, C.3
  • 6
    • 0027241564 scopus 로고
    • Th2 cells mediate IL-4-dependent local tissue inflammation
    • Muller KM, Jaunin F, Masouye I et al. Th2 cells mediate IL-4-dependent local tissue inflammation. J Immunol 1993 150 : 5576 84.
    • (1993) J Immunol , vol.150 , pp. 5576-84
    • Muller, K.M.1    Jaunin, F.2    Masouye, I.3
  • 7
    • 0032962127 scopus 로고    scopus 로고
    • Inhibition of allergic contact dermatitis to DNCB but not to oxazolone in interleukin-4-deficient mice
    • Traidl C, Jugert F, Krieg T et al. Inhibition of allergic contact dermatitis to DNCB but not to oxazolone in interleukin-4-deficient mice. J Invest Dermatol 1999 112 : 476 82.
    • (1999) J Invest Dermatol , vol.112 , pp. 476-82
    • Traidl, C.1    Jugert, F.2    Krieg, T.3
  • 8
    • 0031944290 scopus 로고    scopus 로고
    • Regulation of immune responses by TGF-beta
    • Letterio JJ, Roberts AB. Regulation of immune responses by TGF-beta. Annu Rev Immunol 1998 16 : 137 61.
    • (1998) Annu Rev Immunol , vol.16 , pp. 137-61
    • Letterio, J.J.1    Roberts, A.B.2
  • 9
    • 0036372440 scopus 로고    scopus 로고
    • Transforming growth factor-beta in T-cell biology
    • Gorelik L, Flavell RA. Transforming growth factor-beta in T-cell biology. Nat Rev Immunol 2002 2 : 46 53.
    • (2002) Nat Rev Immunol , vol.2 , pp. 46-53
    • Gorelik, L.1    Flavell, R.A.2
  • 10
    • 0027248910 scopus 로고
    • Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10
    • Bogdan C, Nathan C. Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10. Ann NY Acad Sci 1993 685 : 713 39.
    • (1993) Ann NY Acad Sci , vol.685 , pp. 713-39
    • Bogdan, C.1    Nathan, C.2
  • 11
    • 0033561648 scopus 로고    scopus 로고
    • TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells
    • Geissmann F, Revy P, Regnault A et al. TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells. J Immunol 1999 162 : 4567 75.
    • (1999) J Immunol , vol.162 , pp. 4567-75
    • Geissmann, F.1    Revy, P.2    Regnault, A.3
  • 12
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • Chen W, Jin W, Hardegen N et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 2003 198 : 1875 86.
    • (2003) J Exp Med , vol.198 , pp. 1875-86
    • Chen, W.1    Jin, W.2    Hardegen, N.3
  • 13
    • 33750815930 scopus 로고    scopus 로고
    • CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses
    • He D, Wu L, Kim HK et al. CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses. J Immunol 2006 177 : 6852 8.
    • (2006) J Immunol , vol.177 , pp. 6852-8
    • He, D.1    Wu, L.2    Kim, H.K.3
  • 14
    • 32244442562 scopus 로고    scopus 로고
    • TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen M, Hocking RJ, Atkins CJ et al. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006 24 : 179 89.
    • (2006) Immunity , vol.24 , pp. 179-89
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3
  • 15
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
    • Ivanov II, McKenzie BS, Zhou L et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006 126 : 1121 33.
    • (2006) Cell , vol.126 , pp. 1121-33
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3
  • 16
    • 0032442852 scopus 로고    scopus 로고
    • Smads: Transcriptional activators of TGF-beta responses
    • Derynck R, Zhang Y, Feng XH. Smads: transcriptional activators of TGF-beta responses. Cell 1998 95 : 737 40.
    • (1998) Cell , vol.95 , pp. 737-40
    • Derynck, R.1    Zhang, Y.2    Feng, X.H.3
  • 17
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003 425 : 577 84.
    • (2003) Nature , vol.425 , pp. 577-84
    • Derynck, R.1    Zhang, Y.E.2
  • 18
    • 33645523595 scopus 로고    scopus 로고
    • Smad3 knock-out mice as a useful model to study intestinal fibrogenesis
    • Zanninelli G, Vetuschi A, Sferra R et al. Smad3 knock-out mice as a useful model to study intestinal fibrogenesis. World J Gastroenterol 2006 12 : 1211 18.
    • (2006) World J Gastroenterol , vol.12 , pp. 1211-18
    • Zanninelli, G.1    Vetuschi, A.2    Sferra, R.3
  • 19
    • 0033104503 scopus 로고    scopus 로고
    • Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta
    • Yang X, Letterio JJ, Lechleider RJ et al. Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta. EMBO J 1999 18 : 1280 91.
    • (1999) EMBO J , vol.18 , pp. 1280-91
    • Yang, X.1    Letterio, J.J.2    Lechleider, R.J.3
  • 20
    • 0033195998 scopus 로고    scopus 로고
    • Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response
    • Ashcroft GS, Yang X, Glick AB et al. Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response. Nat Cell Biol 1999 1 : 260 6.
    • (1999) Nat Cell Biol , vol.1 , pp. 260-6
    • Ashcroft, G.S.1    Yang, X.2    Glick, A.B.3
  • 21
    • 0032934979 scopus 로고    scopus 로고
    • Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction
    • Datto MB, Frederick JP, Pan L et al. Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction. Mol Cell Biol 1999 19 : 2495 504.
    • (1999) Mol Cell Biol , vol.19 , pp. 2495-504
    • Datto, M.B.1    Frederick, J.P.2    Pan, L.3
  • 22
    • 33744994555 scopus 로고    scopus 로고
    • Role of TGFbeta in skin inflammation and carcinogenesis
    • Li AG, Lu SL, Han G et al. Role of TGFbeta in skin inflammation and carcinogenesis. Mol Carcinog 2006 45 : 389 96.
    • (2006) Mol Carcinog , vol.45 , pp. 389-96
    • Li, A.G.1    Lu, S.L.2    Han, G.3
  • 23
    • 33748155711 scopus 로고    scopus 로고
    • Alterations of TGF-beta/Smad mRNA expression in atopic dermatitis following narrow-band ultraviolet B phototherapy: Results of a pilot study
    • Gambichler T, Tomi NS, Skrygan M et al. Alterations of TGF-beta/Smad mRNA expression in atopic dermatitis following narrow-band ultraviolet B phototherapy: results of a pilot study. J Dermatol Sci 2006 44 : 56 8.
    • (2006) J Dermatol Sci , vol.44 , pp. 56-8
    • Gambichler, T.1    Tomi, N.S.2    Skrygan, M.3
  • 24
    • 0030809176 scopus 로고    scopus 로고
    • Trimellitic anhydride-sensitive mouse as an animal model for contact urticaria
    • Lauerma AI, Fenn B, Maibach HI. Trimellitic anhydride-sensitive mouse as an animal model for contact urticaria. J Appl Toxicol 1997 17 : 357 60.
    • (1997) J Appl Toxicol , vol.17 , pp. 357-60
    • Lauerma, A.I.1    Fenn, B.2    Maibach, H.I.3
  • 25
    • 0037378521 scopus 로고    scopus 로고
    • Epicutaneous natural rubber latex sensitization induces T helper 2-type dermatitis and strong prohevein-specific IgE response
    • Lehto M, Koivuluhta M, Wang G et al. Epicutaneous natural rubber latex sensitization induces T helper 2-type dermatitis and strong prohevein-specific IgE response. J Invest Dermatol 2003 120 : 633 40.
    • (2003) J Invest Dermatol , vol.120 , pp. 633-40
    • Lehto, M.1    Koivuluhta, M.2    Wang, G.3
  • 26
    • 29144487921 scopus 로고    scopus 로고
    • Topical superantigen exposure induces epidermal accumulation of CD8+ T cells, a mixed Th1/Th2-type dermatitis and vigorous production of IgE antibodies in the murine model of atopic dermatitis
    • Savinko T, Lauerma A, Lehtimaki S et al. Topical superantigen exposure induces epidermal accumulation of CD8+ T cells, a mixed Th1/Th2-type dermatitis and vigorous production of IgE antibodies in the murine model of atopic dermatitis. J Immunol 2005 175 : 8320 6.
    • (2005) J Immunol , vol.175 , pp. 8320-6
    • Savinko, T.1    Lauerma, A.2    Lehtimaki, S.3
  • 27
    • 17144405680 scopus 로고    scopus 로고
    • Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma
    • Hawrylowicz CM, O'Garra A. Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma. Nat Rev Immunol 2005 5 : 271 83.
    • (2005) Nat Rev Immunol , vol.5 , pp. 271-83
    • Hawrylowicz, C.M.1    O'Garra, A.2
  • 28
    • 85047691550 scopus 로고    scopus 로고
    • Critical role of IL-10 in the induction of low zone tolerance to contact allergens
    • Maurer M, Seidel-Guyenot W, Metz M et al. Critical role of IL-10 in the induction of low zone tolerance to contact allergens. J Clin Invest 2003 112 : 432 9.
    • (2003) J Clin Invest , vol.112 , pp. 432-9
    • Maurer, M.1    Seidel-Guyenot, W.2    Metz, M.3
  • 29
    • 0036086293 scopus 로고    scopus 로고
    • Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice
    • Zhao J, Shi W, Wang YL et al. Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice. Am J Physiol Lung Cell Mol Physiol 2002 282 : L585 93.
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.282
    • Zhao, J.1    Shi, W.2    Wang, Y.L.3
  • 30
    • 34447568256 scopus 로고    scopus 로고
    • Smad3 signal transducer regulates skin inflammation and specific IgE response in murine model of atopic dermatitis
    • Anthoni M, Wang G, Deng C et al. Smad3 signal transducer regulates skin inflammation and specific IgE response in murine model of atopic dermatitis. J Invest Dermatol 2007 127 : 1923 9.
    • (2007) J Invest Dermatol , vol.127 , pp. 1923-9
    • Anthoni, M.1    Wang, G.2    Deng, C.3
  • 31
    • 0027407109 scopus 로고
    • Endothelial-leukocyte adhesion molecules
    • Bevilacqua MP. Endothelial-leukocyte adhesion molecules. Annu Rev Immunol 1993 11 : 767 804.
    • (1993) Annu Rev Immunol , vol.11 , pp. 767-804
    • Bevilacqua, M.P.1
  • 32
    • 0033485401 scopus 로고    scopus 로고
    • Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells
    • McDonald PP, Fadok VA, Bratton D et al. Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells. J Immunol 1999 163 : 6164 72.
    • (1999) J Immunol , vol.163 , pp. 6164-72
    • McDonald, P.P.1    Fadok, V.A.2    Bratton, D.3
  • 33
    • 0029913787 scopus 로고    scopus 로고
    • T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: Interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (Il) 4/Il-10-producing (Th2) negative regulatory CD4+ T cells
    • Xu H, DiIulio NA, Fairchild RL. T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (Il) 4/Il-10-producing (Th2) negative regulatory CD4+ T cells. J Exp Med 1996 183 : 1001 12.
    • (1996) J Exp Med , vol.183 , pp. 1001-12
    • Xu, H.1    Diiulio, N.A.2    Fairchild, R.L.3
  • 34
    • 0036754255 scopus 로고    scopus 로고
    • Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses
    • Nakae S, Komiyama Y, Nambu A et al. Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 2002 17 : 375 87.
    • (2002) Immunity , vol.17 , pp. 375-87
    • Nakae, S.1    Komiyama, Y.2    Nambu, A.3
  • 35
    • 17844410676 scopus 로고    scopus 로고
    • Epicutaneous immunization induces alphabeta T-cell receptor CD4 CD8 double-positive non-specific suppressor T cells that inhibit contact sensitivity via transforming growth factor-beta
    • Szczepanik M, Bryniarski K, Tutaj M et al. Epicutaneous immunization induces alphabeta T-cell receptor CD4 CD8 double-positive non-specific suppressor T cells that inhibit contact sensitivity via transforming growth factor-beta. Immunology 2005 115 : 42 54.
    • (2005) Immunology , vol.115 , pp. 42-54
    • Szczepanik, M.1    Bryniarski, K.2    Tutaj, M.3
  • 36
    • 17144400393 scopus 로고    scopus 로고
    • TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
    • Marie JC, Letterio JJ, Gavin M et al. TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J Exp Med 2005 201 : 1061 7.
    • (2005) J Exp Med , vol.201 , pp. 1061-7
    • Marie, J.C.1    Letterio, J.J.2    Gavin, M.3
  • 37
    • 29244435493 scopus 로고    scopus 로고
    • Inducing and expanding regulatory T cell populations by foreign antigen
    • Kretschmer K, Apostolou I, Hawiger D et al. Inducing and expanding regulatory T cell populations by foreign antigen. Nat Immunol 2005 6 : 1219 27.
    • (2005) Nat Immunol , vol.6 , pp. 1219-27
    • Kretschmer, K.1    Apostolou, I.2    Hawiger, D.3
  • 38
    • 38349095578 scopus 로고    scopus 로고
    • Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
    • Tone Y, Furuuchi K, Kojima Y et al. Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer. Nat Immunol 2008 9 : 194 202.
    • (2008) Nat Immunol , vol.9 , pp. 194-202
    • Tone, Y.1    Furuuchi, K.2    Kojima, Y.3
  • 39
    • 0030769920 scopus 로고    scopus 로고
    • Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells
    • Sallusto F, Mackay CR, Lanzavecchia A. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 1997 277 : 2005 7.
    • (1997) Science , vol.277 , pp. 2005-7
    • Sallusto, F.1    MacKay, C.R.2    Lanzavecchia, A.3
  • 40
    • 0030587122 scopus 로고    scopus 로고
    • In vivo fate of the inflammatory macrophage during the resolution of inflammation: Inflammatory macrophages do not die locally, but emigrate to the draining lymph nodes
    • Bellingan GJ, Caldwell H, Howie SE et al. In vivo fate of the inflammatory macrophage during the resolution of inflammation: inflammatory macrophages do not die locally, but emigrate to the draining lymph nodes. J Immunol 1996 157 : 2577 85.
    • (1996) J Immunol , vol.157 , pp. 2577-85
    • Bellingan, G.J.1    Caldwell, H.2    Howie, S.E.3
  • 41
    • 0034257928 scopus 로고    scopus 로고
    • The chemokine macrophage-inflammatory protein-1 alpha and its receptor CCR1 control pulmonary inflammation and antiviral host defense in paramyxovirus infection
    • Domachowske JB, Bonville CA, Gao JL et al. The chemokine macrophage-inflammatory protein-1 alpha and its receptor CCR1 control pulmonary inflammation and antiviral host defense in paramyxovirus infection. J Immunol 2000 165 : 2677 82.
    • (2000) J Immunol , vol.165 , pp. 2677-82
    • Domachowske, J.B.1    Bonville, C.A.2    Gao, J.L.3
  • 42
    • 0032925898 scopus 로고    scopus 로고
    • Neutralization of macrophage inflammatory protein 2 (MIP-2) and MIP-1alpha attenuates neutrophil recruitment in the central nervous system during experimental bacterial meningitis
    • Diab A, Abdalla H, Li HL et al. Neutralization of macrophage inflammatory protein 2 (MIP-2) and MIP-1alpha attenuates neutrophil recruitment in the central nervous system during experimental bacterial meningitis. Infect Immun 1999 67 : 2590 601.
    • (1999) Infect Immun , vol.67 , pp. 2590-601
    • Diab, A.1    Abdalla, H.2    Li, H.L.3
  • 43
    • 0029061668 scopus 로고
    • Role of macrophage inflammatory protein-1 alpha (MIP-1 alpha) in acute lung injury in rats
    • Shanley TP, Schmal H, Friedl HP et al. Role of macrophage inflammatory protein-1 alpha (MIP-1 alpha) in acute lung injury in rats. J Immunol 1995 154 : 4793 802.
    • (1995) J Immunol , vol.154 , pp. 4793-802
    • Shanley, T.P.1    Schmal, H.2    Friedl, H.P.3
  • 44
    • 0034144269 scopus 로고    scopus 로고
    • Chemokines: A new classification system and their role in immunity
    • Zlotnik A, Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity 2000 12 : 121 7.
    • (2000) Immunity , vol.12 , pp. 121-7
    • Zlotnik, A.1    Yoshie, O.2
  • 45
    • 0032499260 scopus 로고    scopus 로고
    • Chemokines and leukocyte traffic
    • Baggiolini M. Chemokines and leukocyte traffic. Nature 1998 392 : 565 8.
    • (1998) Nature , vol.392 , pp. 565-8
    • Baggiolini, M.1
  • 46
    • 20444497989 scopus 로고    scopus 로고
    • Targeted identification of glucocorticoid-attenuated response genes: In vitro and in vivo models
    • Smith JB, Herschman HR. Targeted identification of glucocorticoid- attenuated response genes: in vitro and in vivo models. Proc Am Thorac Soc 2004 1 : 275 81.
    • (2004) Proc Am Thorac Soc , vol.1 , pp. 275-81
    • Smith, J.B.1    Herschman, H.R.2
  • 47
    • 0141782259 scopus 로고    scopus 로고
    • Gelatinase B/MMP-9 and neutrophil collagenase/MMP-8 process the chemokines human GCP-2/CXCL6, ENA-78/CXCL5 and mouse GCP-2/LIX and modulate their physiological activities
    • van den Steen PE, Wuyts A, Husson SJ et al. Gelatinase B/MMP-9 and neutrophil collagenase/MMP-8 process the chemokines human GCP-2/CXCL6, ENA-78/CXCL5 and mouse GCP-2/LIX and modulate their physiological activities. Eur J Biochem 2003 270 : 3739 49.
    • (2003) Eur J Biochem , vol.270 , pp. 3739-49
    • Van Den Steen, P.E.1    Wuyts, A.2    Husson, S.J.3
  • 48
    • 0034711282 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1 inhibition of macrophage activation is mediated via Smad3
    • Werner F, Jain MK, Feinberg MW et al. Transforming growth factor-beta 1 inhibition of macrophage activation is mediated via Smad3. J Biol Chem 2000 275 : 36653 8.
    • (2000) J Biol Chem , vol.275 , pp. 36653-8
    • Werner, F.1    Jain, M.K.2    Feinberg, M.W.3
  • 49
    • 0037216818 scopus 로고    scopus 로고
    • Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma
    • Hellings PW, Kasran A, Liu Z et al. Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma. Am J Respir Cell Mol Biol 2003 28 : 42 50.
    • (2003) Am J Respir Cell Mol Biol , vol.28 , pp. 42-50
    • Hellings, P.W.1    Kasran, A.2    Liu, Z.3


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