Monolayered multipolymeric buccal films with drug and polymers of opposing solubilities for ARV therapy: Physico-mechanical evaluation and molecular mechanics modelling

International Journal of Pharmaceutics

Volumn 455, Issue 1-2, 2013, Pages 197-212

  Jones, Elsabé ^a   Ojewole, Elizabeth ^a   Pillay, Viness ^b   Kumar, Pradeep ^b   Rambharose, Sanjeev ^a   Govender, Thirumala ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Buccal; Co blended polymers; Didanosine; Films; Physico mechanical properties; Static lattice atomistic simulations

Indexed keywords

DIDANOSINE; EUDRAGIT; HYDROXYPROPYLMETHYLCELLULOSE; PLASTICIZER; POLYMER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BUCCAL DRUG ADMINISTRATION; COMPUTER MODEL; CONTROLLED STUDY; DRUG PENETRATION; DRUG RELEASE; FILM COATING; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; IN VITRO STUDY; MODEL; MOLECULAR MECHANICS; NONHUMAN; PERMEABILITY; PH; PRIORITY JOURNAL; SOLUBILITY; STEADY STATE; SURFACE PROPERTY;

BUCCAL; CO-BLENDED POLYMERS; DIDANOSINE; FILMS; PHYSICO-MECHANICAL PROPERTIES; STATIC LATTICE ATOMISTIC SIMULATIONS;

ADMINISTRATION, BUCCAL; ANTI-RETROVIRAL AGENTS; DIDANOSINE; DRUG DELIVERY SYSTEMS; MODELS, MOLECULAR; POLYMERS; SOLUBILITY;

EID: 84884155957     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.07.037     Document Type: Article

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