메뉴 건너뛰기




Volumn 20, Issue 9, 2013, Pages 1185-1192

Glycogen synthase kinase-3β (GSK-3β) and its dysregulation in glioblastoma multiforme

Author keywords

Cancer; Glioblastoma multiforme; GSK 3 ; PI3 K; Wnt

Indexed keywords

BETA CATENIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM; MYC PROTEIN; PLATELET DERIVED GROWTH FACTOR; WNT PROTEIN;

EID: 84883110364     PISSN: 09675868     EISSN: 15322653     Source Type: Journal    
DOI: 10.1016/j.jocn.2013.02.003     Document Type: Review
Times cited : (32)

References (161)
  • 1
    • 77955462853 scopus 로고    scopus 로고
    • Global patterns of cancer incidence and mortality rates and trends. Cancer epidemiology, biomarkers & prevention: A publication of the American Association for Cancer Research
    • A. Jemal, M.M. Center, and C. DeSantis Global patterns of cancer incidence and mortality rates and trends. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research Am Soc Prev Oncol 19 2010 1893 1907
    • (2010) Am Soc Prev Oncol , vol.19 , pp. 1893-1907
    • Jemal, A.1    Center, M.M.2    Desantis, C.3
  • 2
    • 0034659906 scopus 로고    scopus 로고
    • World Health Organization classification of tumors
    • P. Kleihues, and L.H. Sobin World Health Organization classification of tumors Cancer 88 2000 2887
    • (2000) Cancer , vol.88 , pp. 2887
    • Kleihues, P.1    Sobin, L.H.2
  • 3
    • 0031963921 scopus 로고    scopus 로고
    • Survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histological type: An analysis based on Surveillance, epidemiology, and end results (SEER) data, 1973-1991
    • F.G. Davis, S. Freels, and J. Grutsch Survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histological type: an analysis based on Surveillance, epidemiology, and end results (SEER) data, 1973-1991 J Neurosurg 88 1998 1 10
    • (1998) J Neurosurg , vol.88 , pp. 1-10
    • Davis, F.G.1    Freels, S.2    Grutsch, J.3
  • 4
    • 79960111080 scopus 로고    scopus 로고
    • Phase II study of aflibercept in recurrent malignant glioma: A North American brain tumor consortium study
    • J.F. de Groot, K.R. Lamborn, and S.M. Chang Phase II study of aflibercept in recurrent malignant glioma: a North American brain tumor consortium study J Clin Oncol 29 2011 2689 2695
    • (2011) J Clin Oncol , vol.29 , pp. 2689-2695
    • De Groot, J.F.1    Lamborn, K.R.2    Chang, S.M.3
  • 5
    • 26944473246 scopus 로고    scopus 로고
    • Annual report to the nation on the status of cancer, 1975-2002, featuring population-based trends in cancer treatment
    • B.K. Edwards, M.L. Brown, and P.A. Wingo Annual report to the nation on the status of cancer, 1975-2002, featuring population-based trends in cancer treatment J Natl Cancer Inst 97 2005 1407 1427
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1407-1427
    • Edwards, B.K.1    Brown, M.L.2    Wingo, P.A.3
  • 6
    • 84868303739 scopus 로고    scopus 로고
    • A retrospective study of primary cerebellar glioblastoma multiforme in adults
    • C.V. Gopalakrishnan, A. Dhakoji, and S. Nair A retrospective study of primary cerebellar glioblastoma multiforme in adults J Clin Neurosci 19 2012 1684 1688
    • (2012) J Clin Neurosci , vol.19 , pp. 1684-1688
    • Gopalakrishnan, C.V.1    Dhakoji, A.2    Nair, S.3
  • 7
    • 79959956310 scopus 로고    scopus 로고
    • A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American brain tumor consortium study 03-03
    • F.M. Iwamoto, K.R. Lamborn, and J.G. Kuhn A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American brain tumor consortium study 03-03 Neuro Oncol 13 2011 509 516
    • (2011) Neuro Oncol , vol.13 , pp. 509-516
    • Iwamoto, F.M.1    Lamborn, K.R.2    Kuhn, J.G.3
  • 8
    • 70350710019 scopus 로고    scopus 로고
    • Survival analysis of 205 patients with glioblastoma multiforme: Clinical characteristics, treatment and prognosis in China
    • X. Ma, Y. Lv, and J. Liu Survival analysis of 205 patients with glioblastoma multiforme: clinical characteristics, treatment and prognosis in China J Clin Neurosci 16 2009 1595 1598
    • (2009) J Clin Neurosci , vol.16 , pp. 1595-1598
    • Ma, X.1    Lv, Y.2    Liu, J.3
  • 9
    • 3142660253 scopus 로고    scopus 로고
    • Photodynamic therapy of brain tumours: Evaluation of porphyrin uptake versus clinical outcome
    • S.S. Stylli, M. Howes, and L. MacGregor Photodynamic therapy of brain tumours: evaluation of porphyrin uptake versus clinical outcome J Clin Neurosci 11 2004 584 596
    • (2004) J Clin Neurosci , vol.11 , pp. 584-596
    • Stylli, S.S.1    Howes, M.2    MacGregor, L.3
  • 10
    • 33748467188 scopus 로고    scopus 로고
    • Photodynamic therapy of cerebral glioma - A review. Part II - Clinical studies
    • S.S. Stylli, and A.H. Kaye Photodynamic therapy of cerebral glioma - a review. Part II - clinical studies J Clin Neurosci 13 2006 709 717
    • (2006) J Clin Neurosci , vol.13 , pp. 709-717
    • Stylli, S.S.1    Kaye, A.H.2
  • 11
    • 19744362839 scopus 로고    scopus 로고
    • Photodynamic therapy of high grade glioma - Long term survival
    • S.S. Stylli, A.H. Kaye, and L. MacGregor Photodynamic therapy of high grade glioma - long term survival J Clin Neurosci 12 2005 389 398
    • (2005) J Clin Neurosci , vol.12 , pp. 389-398
    • Stylli, S.S.1    Kaye, A.H.2    MacGregor, L.3
  • 12
    • 77349117235 scopus 로고    scopus 로고
    • Survival comparison between glioblastoma multiforme and other incurable cancers
    • B. Tran, and M.A. Rosenthal Survival comparison between glioblastoma multiforme and other incurable cancers J Clin Neurosci 17 2010 417 421
    • (2010) J Clin Neurosci , vol.17 , pp. 417-421
    • Tran, B.1    Rosenthal, M.A.2
  • 13
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • R. Stupp, W.P. Mason, and M.J. van den Bent Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N Engl J Med 352 2005 987 996
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    Van Den Bent, M.J.3
  • 14
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • S. Bao, Q. Wu, and R.E. McLendon Glioma stem cells promote radioresistance by preferential activation of the DNA damage response Nature 444 2006 756 760
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3
  • 15
    • 0034741232 scopus 로고    scopus 로고
    • Treatment of malignant glioma: A problem beyond the margins of resection
    • A. Giese, and M. Westphal Treatment of malignant glioma: a problem beyond the margins of resection J Cancer Res Clin Oncol 127 2001 217 225
    • (2001) J Cancer Res Clin Oncol , vol.127 , pp. 217-225
    • Giese, A.1    Westphal, M.2
  • 16
    • 41049103648 scopus 로고    scopus 로고
    • Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: A North American brain tumor consortium study
    • M.D. Prados, W.K. Yung, and P.Y. Wen Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study Cancer Chemother Pharmacol 61 2008 1059 1067
    • (2008) Cancer Chemother Pharmacol , vol.61 , pp. 1059-1067
    • Prados, M.D.1    Yung, W.K.2    Wen, P.Y.3
  • 17
    • 84867102141 scopus 로고    scopus 로고
    • Regulation of glycogen synthase kinase-3 beta (GSK-3beta) by the Akt pathway in gliomas
    • R.J. Atkins, J. Dimou, and L. Paradiso Regulation of glycogen synthase kinase-3 beta (GSK-3beta) by the Akt pathway in gliomas J Clin Neurosci 19 2012 1558 1563
    • (2012) J Clin Neurosci , vol.19 , pp. 1558-1563
    • Atkins, R.J.1    Dimou, J.2    Paradiso, L.3
  • 18
    • 80052903796 scopus 로고    scopus 로고
    • Lithium promotes neural precursor cell proliferation: Evidence for the involvement of the non-canonical GSK-3beta-NF-AT signaling
    • Z. Qu, D. Sun, and W. Young Lithium promotes neural precursor cell proliferation: evidence for the involvement of the non-canonical GSK-3beta-NF-AT signaling Cell Biosci 1 2011 18
    • (2011) Cell Biosci , vol.1 , pp. 18
    • Qu, Z.1    Sun, D.2    Young, W.3
  • 19
    • 84856505322 scopus 로고    scopus 로고
    • Notch1 promotes glioma cell migration and invasion by stimulating beta-catenin and NF-kappaB signaling via AKT activation
    • X. Zhang, T. Chen, and J. Zhang Notch1 promotes glioma cell migration and invasion by stimulating beta-catenin and NF-kappaB signaling via AKT activation Cancer Sci 103 2012 181 190
    • (2012) Cancer Sci , vol.103 , pp. 181-190
    • Zhang, X.1    Chen, T.2    Zhang, J.3
  • 20
    • 77949268513 scopus 로고    scopus 로고
    • GSK3beta regulates differentiation and growth arrest in glioblastoma
    • S. Korur, R.M. Huber, and B. Sivasankaran GSK3beta regulates differentiation and growth arrest in glioblastoma PLoS ONE 4 2009 e7443
    • (2009) PLoS ONE , vol.4 , pp. 7443
    • Korur, S.1    Huber, R.M.2    Sivasankaran, B.3
  • 21
    • 0034859101 scopus 로고    scopus 로고
    • The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
    • C.A. Grimes, and R.S. Jope The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling Prog Neurobiol 65 2001 391 426
    • (2001) Prog Neurobiol , vol.65 , pp. 391-426
    • Grimes, C.A.1    Jope, R.S.2
  • 22
    • 0025286104 scopus 로고
    • Molecular cloning and expression of glycogen synthase kinase-3/factor A
    • J.R. Woodgett Molecular cloning and expression of glycogen synthase kinase-3/factor A EMBO J 9 1990 2431 2438
    • (1990) EMBO J , vol.9 , pp. 2431-2438
    • Woodgett, J.R.1
  • 23
    • 0344245499 scopus 로고    scopus 로고
    • Expression analysis of glycogen synthase kinase-3 in human tissues
    • K.F. Lau, C.C. Miller, and B.H. Anderton Expression analysis of glycogen synthase kinase-3 in human tissues J Pept Res 54 1999 85 91
    • (1999) J Pept Res , vol.54 , pp. 85-91
    • Lau, K.F.1    Miller, C.C.2    Anderton, B.H.3
  • 24
    • 78650436439 scopus 로고    scopus 로고
    • Allosteric regulation of glycogen synthase kinase 3beta: A theoretical study
    • I. Buch, D. Fishelovitch, and N. London Allosteric regulation of glycogen synthase kinase 3beta: a theoretical study Biochemistry 49 2010 10890 10901
    • (2010) Biochemistry , vol.49 , pp. 10890-10901
    • Buch, I.1    Fishelovitch, D.2    London, N.3
  • 25
    • 0035875098 scopus 로고    scopus 로고
    • Crystal structure of glycogen synthase kinase 3 beta: Structural basis for phosphate-primed substrate specificity and autoinhibition
    • R. Dajani, E. Fraser, and S.M. Roe Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition Cell 105 2001 721 732
    • (2001) Cell , vol.105 , pp. 721-732
    • Dajani, R.1    Fraser, E.2    Roe, S.M.3
  • 26
    • 0032533225 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
    • J.A. Diehl, M. Cheng, and M.F. Roussel Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization Genes Dev 12 1998 3499 3511
    • (1998) Genes Dev , vol.12 , pp. 3499-3511
    • Diehl, J.A.1    Cheng, M.2    Roussel, M.F.3
  • 27
    • 0029664368 scopus 로고    scopus 로고
    • Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly
    • B. Rubinfeld, I. Albert, and E. Porfiri Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly Science 272 1996 1023 1026
    • (1996) Science , vol.272 , pp. 1023-1026
    • Rubinfeld, B.1    Albert, I.2    Porfiri, E.3
  • 28
    • 0037155691 scopus 로고    scopus 로고
    • Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
    • C. Liu, Y. Li, and M. Semenov Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism Cell 108 2002 837 847
    • (2002) Cell , vol.108 , pp. 837-847
    • Liu, C.1    Li, Y.2    Semenov, M.3
  • 29
    • 33646001713 scopus 로고    scopus 로고
    • Threonine 41 in beta-catenin serves as a key phosphorylation relay residue in beta-catenin degradation
    • G. Wu, and X. He Threonine 41 in beta-catenin serves as a key phosphorylation relay residue in beta-catenin degradation Biochemistry 45 2006 5319 5323
    • (2006) Biochemistry , vol.45 , pp. 5319-5323
    • Wu, G.1    He, X.2
  • 30
    • 0030978351 scopus 로고    scopus 로고
    • Beta-catenin is a target for the ubiquitin-proteasome pathway
    • H. Aberle, A. Bauer, and J. Stappert Beta-catenin is a target for the ubiquitin-proteasome pathway EMBO J 16 1997 3797 3804
    • (1997) EMBO J , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3
  • 31
    • 0030779038 scopus 로고    scopus 로고
    • Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin
    • K. Orford, C. Crockett, and J.P. Jensen Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin J Biol Chem 272 1997 24735 24738
    • (1997) J Biol Chem , vol.272 , pp. 24735-24738
    • Orford, K.1    Crockett, C.2    Jensen, J.P.3
  • 32
    • 0034934624 scopus 로고    scopus 로고
    • CRMP-2 induces axons in cultured hippocampal neurons
    • N. Inagaki, K. Chihara, and N. Arimura CRMP-2 induces axons in cultured hippocampal neurons Nat Neurosci 4 2001 781 782
    • (2001) Nat Neurosci , vol.4 , pp. 781-782
    • Inagaki, N.1    Chihara, K.2    Arimura, N.3
  • 33
    • 11844297771 scopus 로고    scopus 로고
    • GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity
    • T. Yoshimura, Y. Kawano, and N. Arimura GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity Cell 120 2005 137 149
    • (2005) Cell , vol.120 , pp. 137-149
    • Yoshimura, T.1    Kawano, Y.2    Arimura, N.3
  • 34
    • 0036048640 scopus 로고    scopus 로고
    • CRMP-2 binds to tubulin heterodimers to promote microtubule assembly
    • Y. Fukata, T.J. Itoh, and T. Kimura CRMP-2 binds to tubulin heterodimers to promote microtubule assembly Nat Cell Biol 4 2002 583 591
    • (2002) Nat Cell Biol , vol.4 , pp. 583-591
    • Fukata, Y.1    Itoh, T.J.2    Kimura, T.3
  • 35
    • 33847359256 scopus 로고    scopus 로고
    • Targeting malignant glioma survival signalling to improve clinical outcomes
    • M.L. Wong, A.H. Kaye, and C.M. Hovens Targeting malignant glioma survival signalling to improve clinical outcomes J Clin Neurosci 14 2007 301 308
    • (2007) J Clin Neurosci , vol.14 , pp. 301-308
    • Wong, M.L.1    Kaye, A.H.2    Hovens, C.M.3
  • 36
    • 11844260672 scopus 로고    scopus 로고
    • Both the establishment and the maintenance of neuronal polarity require active mechanisms: Critical roles of GSK-3beta and its upstream regulators
    • H. Jiang, W. Guo, and X. Liang Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators Cell 120 2005 123 135
    • (2005) Cell , vol.120 , pp. 123-135
    • Jiang, H.1    Guo, W.2    Liang, X.3
  • 37
    • 2342629917 scopus 로고    scopus 로고
    • Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity
    • T. Nishimura, K. Kato, and T. Yamaguchi Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity Nat Cell Biol 6 2004 328 334
    • (2004) Nat Cell Biol , vol.6 , pp. 328-334
    • Nishimura, T.1    Kato, K.2    Yamaguchi, T.3
  • 38
    • 0037428076 scopus 로고    scopus 로고
    • Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity
    • S.H. Shi, L.Y. Jan, and Y.N. Jan Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity Cell 112 2003 63 75
    • (2003) Cell , vol.112 , pp. 63-75
    • Shi, S.H.1    Jan, L.Y.2    Jan, Y.N.3
  • 39
    • 0031800971 scopus 로고    scopus 로고
    • Inhibition of GSK-3beta leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium
    • F.R. Lucas, R.G. Goold, and P.R. Gordon-Weeks Inhibition of GSK-3beta leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium J Cell Sci 111 1998 1351 1361
    • (1998) J Cell Sci , vol.111 , pp. 1351-1361
    • Lucas, F.R.1    Goold, R.G.2    Gordon-Weeks, P.R.3
  • 40
    • 0028176874 scopus 로고
    • Protein kinase FA/glycogen synthase kinase-3 predominantly phosphorylates the in vivo site Thr97-Pro in brain myelin basic protein: Evidence for Thr-Pro and Ser-Arg-X-X-Ser as consensus sequence motifs
    • J.S. Yu, and S.D. Yang Protein kinase FA/glycogen synthase kinase-3 predominantly phosphorylates the in vivo site Thr97-Pro in brain myelin basic protein: evidence for Thr-Pro and Ser-Arg-X-X-Ser as consensus sequence motifs J Neurochem 62 1994 1596 1603
    • (1994) J Neurochem , vol.62 , pp. 1596-1603
    • Yu, J.S.1    Yang, S.D.2
  • 41
    • 0029936770 scopus 로고    scopus 로고
    • Differential cellular phosphorylation of neurofilament heavy side-arms by glycogen synthase kinase-3 and cyclin-dependent kinase-5
    • S. Guidato, L.H. Tsai, and J. Woodgett Differential cellular phosphorylation of neurofilament heavy side-arms by glycogen synthase kinase-3 and cyclin-dependent kinase-5 J Neurochem 66 1996 1698 1706
    • (1996) J Neurochem , vol.66 , pp. 1698-1706
    • Guidato, S.1    Tsai, L.H.2    Woodgett, J.3
  • 42
    • 0032566623 scopus 로고    scopus 로고
    • Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase
    • J.Z. Wang, Q. Wu, and A. Smith Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase FEBS Lett 436 1998 28 34
    • (1998) FEBS Lett , vol.436 , pp. 28-34
    • Wang, J.Z.1    Wu, Q.2    Smith, A.3
  • 43
    • 0030868557 scopus 로고    scopus 로고
    • Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3
    • M. Hong, D.C. Chen, and P.S. Klein Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3 J Biol Chem 272 1997 25326 25332
    • (1997) J Biol Chem , vol.272 , pp. 25326-25332
    • Hong, M.1    Chen, D.C.2    Klein, P.S.3
  • 44
    • 0034710165 scopus 로고    scopus 로고
    • Cloning and characterization of a novel human ninein protein that interacts with the glycogen synthase kinase 3beta
    • Y.R. Hong, C.H. Chen, and J.H. Chang Cloning and characterization of a novel human ninein protein that interacts with the glycogen synthase kinase 3beta Biochim Biophys Acta 1492 2000 513 516
    • (2000) Biochim Biophys Acta , vol.1492 , pp. 513-516
    • Hong, Y.R.1    Chen, C.H.2    Chang, J.H.3
  • 45
    • 0033604582 scopus 로고    scopus 로고
    • Function of the c-Myc oncogenic transcription factor
    • C.V. Dang, L.M. Resar, and E. Emison Function of the c-Myc oncogenic transcription factor Exp Cell Res 253 1999 63 77
    • (1999) Exp Cell Res , vol.253 , pp. 63-77
    • Dang, C.V.1    Resar, L.M.2    Emison, E.3
  • 46
    • 0028115718 scopus 로고
    • Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo
    • B.J. Pulverer, C. Fisher, and K. Vousden Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo Oncogene 9 1994 59 70
    • (1994) Oncogene , vol.9 , pp. 59-70
    • Pulverer, B.J.1    Fisher, C.2    Vousden, K.3
  • 47
    • 0026508614 scopus 로고
    • Activation of protein kinase C increases phosphorylation of the L-myc trans-activator domain at a GSK-3 target site
    • K. Saksela, T.P. Makela, and K. Hughes Activation of protein kinase C increases phosphorylation of the L-myc trans-activator domain at a GSK-3 target site Oncogene 7 1992 347 353
    • (1992) Oncogene , vol.7 , pp. 347-353
    • Saksela, K.1    Makela, T.P.2    Hughes, K.3
  • 48
    • 0027383378 scopus 로고
    • Phosphorylation sites mapping in the N-terminal domain of c-myc modulate its transforming potential
    • M. Henriksson, A. Bakardjiev, and G. Klein Phosphorylation sites mapping in the N-terminal domain of c-myc modulate its transforming potential Oncogene 8 1993 3199 3209
    • (1993) Oncogene , vol.8 , pp. 3199-3209
    • Henriksson, M.1    Bakardjiev, A.2    Klein, G.3
  • 49
    • 33645211987 scopus 로고    scopus 로고
    • Neural precursor cycling at sonic speed: N-Myc pedals, GSK-3 brakes
    • P.S. Knoepfler, and A.M. Kenney Neural precursor cycling at sonic speed: N-Myc pedals, GSK-3 brakes Cell Cycle 5 2006 47 52
    • (2006) Cell Cycle , vol.5 , pp. 47-52
    • Knoepfler, P.S.1    Kenney, A.M.2
  • 50
    • 0024451982 scopus 로고
    • The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species
    • M. Ozawa, H. Baribault, and R. Kemler The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species EMBO J 8 1989 1711 1717
    • (1989) EMBO J , vol.8 , pp. 1711-1717
    • Ozawa, M.1    Baribault, H.2    Kemler, R.3
  • 51
    • 0001003110 scopus 로고    scopus 로고
    • XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
    • M. Molenaar, M. van de Wetering, and M. Oosterwegel XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos Cell 86 1996 391 399
    • (1996) Cell , vol.86 , pp. 391-399
    • Molenaar, M.1    Van De Wetering, M.2    Oosterwegel, M.3
  • 52
    • 0032729458 scopus 로고    scopus 로고
    • Signaling through beta-catenin and Lef/Tcf
    • A. Novak, and S. Dedhar Signaling through beta-catenin and Lef/Tcf Cell Mol Life Sci 56 1999 523 537
    • (1999) Cell Mol Life Sci , vol.56 , pp. 523-537
    • Novak, A.1    Dedhar, S.2
  • 53
    • 0032539945 scopus 로고    scopus 로고
    • Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription
    • C. Sakanaka, J.B. Weiss, and L.T. Williams Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription Proc Nat Acad Sci USA 95 1998 3020 3023
    • (1998) Proc Nat Acad Sci USA , vol.95 , pp. 3020-3023
    • Sakanaka, C.1    Weiss, J.B.2    Williams, L.T.3
  • 54
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • D.A. Cross, D.R. Alessi, and P. Cohen Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B Nature 378 1995 785 789
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3
  • 55
    • 0027515127 scopus 로고
    • Inactivation of glycogen synthase kinase-3 beta by phosphorylation: New kinase connections in insulin and growth-factor signalling
    • C. Sutherland, I.A. Leighton, and P. Cohen Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling Biochem J 296 1993 15 19
    • (1993) Biochem J , vol.296 , pp. 15-19
    • Sutherland, C.1    Leighton, I.A.2    Cohen, P.3
  • 56
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
    • K. Inoki, Y. Li, and T. Zhu TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling Nat Cell Biol 4 2002 648 657
    • (2002) Nat Cell Biol , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3
  • 58
    • 0029811140 scopus 로고    scopus 로고
    • Expression and characterization of glycogen synthase kinase-3 mutants and their effect on glycogen synthase activity in intact cells
    • H. Eldar-Finkelman, G.M. Argast, and O. Foord Expression and characterization of glycogen synthase kinase-3 mutants and their effect on glycogen synthase activity in intact cells Proc Nat Acad Sci USA 93 1996 10228 10233
    • (1996) Proc Nat Acad Sci USA , vol.93 , pp. 10228-10233
    • Eldar-Finkelman, H.1    Argast, G.M.2    Foord, O.3
  • 59
    • 84872298847 scopus 로고    scopus 로고
    • 3,6-Diamino-4-(2-halophenyl)-2-benzoylthieno[2,3-b]pyridine-5- carbonitriles are selective inhibitors of plasmodium falciparum glycogen synthase kinase-3
    • W. Fugel, A.E. Oberholzer, and B. Gschloessl 3,6-Diamino-4-(2-halophenyl) -2-benzoylthieno[2,3-b]pyridine-5-carbonitriles are selective inhibitors of plasmodium falciparum glycogen synthase kinase-3 J Med Chem 10;56 2013 264 275
    • (2013) J Med Chem , vol.1056 , pp. 264-275
    • Fugel, W.1    Oberholzer, A.E.2    Gschloessl, B.3
  • 60
    • 0034640299 scopus 로고    scopus 로고
    • The Akt-glycogen synthase kinase 3beta pathway regulates transcription of atrial natriuretic factor induced by beta-adrenergic receptor stimulation in cardiac myocytes
    • C. Morisco, D. Zebrowski, and G. Condorelli The Akt-glycogen synthase kinase 3beta pathway regulates transcription of atrial natriuretic factor induced by beta-adrenergic receptor stimulation in cardiac myocytes J Biol Chem 275 2000 14466 14475
    • (2000) J Biol Chem , vol.275 , pp. 14466-14475
    • Morisco, C.1    Zebrowski, D.2    Condorelli, G.3
  • 61
    • 84857482060 scopus 로고    scopus 로고
    • Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: Role of RICTOR in beta1 integrin-mediated cell survival
    • A. Riaz, K.S. Zeller, and S. Johansson Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in beta1 integrin-mediated cell survival PLoS ONE 7 2012 e32081
    • (2012) PLoS ONE , vol.7 , pp. 32081
    • Riaz, A.1    Zeller, K.S.2    Johansson, S.3
  • 62
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • D.D. Sarbassov, D.A. Guertin, and S.M. Ali Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex Science 307 2005 1098 1101
    • (2005) Science , vol.307 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3
  • 63
    • 18644377225 scopus 로고    scopus 로고
    • MTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma
    • X. Hu, P.P. Pandolfi, and Y. Li MTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma Neoplasia 7 2005 356 368
    • (2005) Neoplasia , vol.7 , pp. 356-368
    • Hu, X.1    Pandolfi, P.P.2    Li, Y.3
  • 64
    • 78249279372 scopus 로고    scopus 로고
    • Inhibition of glioblastoma growth by the thiadiazolidinone compound TDZD-8
    • D. Aguilar-Morante, J.A. Morales-Garcia, and M. Sanz-SanCristobal Inhibition of glioblastoma growth by the thiadiazolidinone compound TDZD-8 PLoS ONE 5 2010 e13879
    • (2010) PLoS ONE , vol.5 , pp. 13879
    • Aguilar-Morante, D.1    Morales-Garcia, J.A.2    Sanz-Sancristobal, M.3
  • 65
    • 12944250922 scopus 로고    scopus 로고
    • Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A
    • X. Fang, S.X. Yu, and Y. Lu Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A Proc Nat Acad Sci USA 97 2000 11960 11965
    • (2000) Proc Nat Acad Sci USA , vol.97 , pp. 11960-11965
    • Fang, X.1    Yu, S.X.2    Lu, Y.3
  • 66
    • 0026808555 scopus 로고
    • Differential regulation of glycogen synthase kinase-3 beta by protein kinase C isotypes
    • N. Goode, K. Hughes, and J.R. Woodgett Differential regulation of glycogen synthase kinase-3 beta by protein kinase C isotypes J Biol Chem 267 1992 16878 16882
    • (1992) J Biol Chem , vol.267 , pp. 16878-16882
    • Goode, N.1    Hughes, K.2    Woodgett, J.R.3
  • 67
    • 0034677804 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium
    • G.N. Bijur, P. De Sarno, and R.S. Jope Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium J Biol Chem 275 2000 7583 7590
    • (2000) J Biol Chem , vol.275 , pp. 7583-7590
    • Bijur, G.N.1    De Sarno, P.2    Jope, R.S.3
  • 68
    • 19644367000 scopus 로고    scopus 로고
    • Activation and signaling of the p38 MAP kinase pathway
    • T. Zarubin, and J. Han Activation and signaling of the p38 MAP kinase pathway Cell Res 15 2005 11 18
    • (2005) Cell Res , vol.15 , pp. 11-18
    • Zarubin, T.1    Han, J.2
  • 69
    • 43249106330 scopus 로고    scopus 로고
    • Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation
    • T.M. Thornton, G. Pedraza-Alva, and B. Deng Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation Science 320 2008 667 670
    • (2008) Science , vol.320 , pp. 667-670
    • Thornton, T.M.1    Pedraza-Alva, G.2    Deng, B.3
  • 70
    • 1642494586 scopus 로고    scopus 로고
    • Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event
    • A. Cole, S. Frame, and P. Cohen Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event Biochem J 377 2004 249 255
    • (2004) Biochem J , vol.377 , pp. 249-255
    • Cole, A.1    Frame, S.2    Cohen, P.3
  • 71
    • 0034743516 scopus 로고    scopus 로고
    • Structure of GSK3beta reveals a primed phosphorylation mechanism
    • E. ter Haar, J.T. Coll, and D.A. Austen Structure of GSK3beta reveals a primed phosphorylation mechanism Nat Struct Biol 8 2001 593 596
    • (2001) Nat Struct Biol , vol.8 , pp. 593-596
    • Ter Haar, E.1    Coll, J.T.2    Austen, D.A.3
  • 72
    • 0034804850 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta is tyrosine phosphorylated by PYK2
    • J.A. Hartigan, W.C. Xiong, and G.V. Johnson Glycogen synthase kinase 3beta is tyrosine phosphorylated by PYK2 Biochem Biophys Res Commun 284 2001 485 489
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 485-489
    • Hartigan, J.A.1    Xiong, W.C.2    Johnson, G.V.3
  • 73
    • 0032955426 scopus 로고    scopus 로고
    • Insulin transiently increases tau phosphorylation: Involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase
    • M. Lesort, R.S. Jope, and G.V. Johnson Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase J Neurochem 72 1999 576 584
    • (1999) J Neurochem , vol.72 , pp. 576-584
    • Lesort, M.1    Jope, R.S.2    Johnson, G.V.3
  • 74
    • 0034718421 scopus 로고    scopus 로고
    • Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration
    • R.V. Bhat, J. Shanley, and M.P. Correll Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration Proc Nat Acad Sci USA 97 2000 11074 11079
    • (2000) Proc Nat Acad Sci USA , vol.97 , pp. 11074-11079
    • Bhat, R.V.1    Shanley, J.2    Correll, M.P.3
  • 75
    • 84859736674 scopus 로고    scopus 로고
    • Srebf1a is a key regulator of transcriptional control for adipogenesis
    • J.T. Ayala-Sumuano, C. Velez-Delvalle, and A. Beltran-Langarica Srebf1a is a key regulator of transcriptional control for adipogenesis Sci Rep 1 2011 178
    • (2011) Sci Rep , vol.1 , pp. 178
    • Ayala-Sumuano, J.T.1    Velez-Delvalle, C.2    Beltran-Langarica, A.3
  • 76
    • 0031695652 scopus 로고    scopus 로고
    • Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons
    • A. Takashima, T. Honda, and K. Yasutake Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons Neurosci Res 31 1998 317 323
    • (1998) Neurosci Res , vol.31 , pp. 317-323
    • Takashima, A.1    Honda, T.2    Yasutake, K.3
  • 77
    • 0027255817 scopus 로고
    • Glycogen synthase kinase 3 beta is identical to tau protein kinase i generating several epitopes of paired helical filaments
    • K. Ishiguro, A. Shiratsuchi, and S. Sato Glycogen synthase kinase 3 beta is identical to tau protein kinase I generating several epitopes of paired helical filaments FEBS Lett 325 1993 167 172
    • (1993) FEBS Lett , vol.325 , pp. 167-172
    • Ishiguro, K.1    Shiratsuchi, A.2    Sato, S.3
  • 78
    • 36348935683 scopus 로고    scopus 로고
    • Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway
    • M. Townsend, T. Mehta, and D.J. Selkoe Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway J Biol Chem 282 2007 33305 33312
    • (2007) J Biol Chem , vol.282 , pp. 33305-33312
    • Townsend, M.1    Mehta, T.2    Selkoe, D.J.3
  • 79
    • 38149054804 scopus 로고    scopus 로고
    • Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling
    • X. Guo, A. Ramirez, and D.S. Waddell Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling Genes Dev 22 2008 106 120
    • (2008) Genes Dev , vol.22 , pp. 106-120
    • Guo, X.1    Ramirez, A.2    Waddell, D.S.3
  • 80
    • 25444513654 scopus 로고    scopus 로고
    • Re-evaluating the role of Frat in Wnt-signal transduction
    • R. van Amerongen, and A. Berns Re-evaluating the role of Frat in Wnt-signal transduction Cell Cycle 4 2005 1065 1072
    • (2005) Cell Cycle , vol.4 , pp. 1065-1072
    • Van Amerongen, R.1    Berns, A.2
  • 81
    • 0032562603 scopus 로고    scopus 로고
    • Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta
    • J. Behrens, B.A. Jerchow, and M. Wurtele Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta Science 280 1998 596 599
    • (1998) Science , vol.280 , pp. 596-599
    • Behrens, J.1    Jerchow, B.A.2    Wurtele, M.3
  • 82
    • 0033574527 scopus 로고    scopus 로고
    • Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability
    • H. Yamamoto, S. Kishida, and M. Kishida Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability J Biol Chem 274 1999 10681 10684
    • (1999) J Biol Chem , vol.274 , pp. 10681-10684
    • Yamamoto, H.1    Kishida, S.2    Kishida, M.3
  • 83
    • 0032511194 scopus 로고    scopus 로고
    • GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis
    • C. Yost, G.H. Farr 3rd, and S.B. Pierce GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis Cell 93 1998 1031 1041
    • (1998) Cell , vol.93 , pp. 1031-1041
    • Yost, C.1    Farr III, G.H.2    Pierce, S.B.3
  • 84
    • 0034695912 scopus 로고    scopus 로고
    • Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification
    • G.H. Farr 3rd, D.M. Ferkey, and C. Yost Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification J Cell Biol 148 2000 691 702
    • (2000) J Cell Biol , vol.148 , pp. 691-702
    • Farr III, G.H.1    Ferkey, D.M.2    Yost, C.3
  • 85
    • 73849115661 scopus 로고    scopus 로고
    • Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways
    • R. van Amerongen, M.C. Nawijn, and J.P. Lambooij Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways Oncogene 29 2010 93 104
    • (2010) Oncogene , vol.29 , pp. 93-104
    • Van Amerongen, R.1    Nawijn, M.C.2    Lambooij, J.P.3
  • 86
    • 0032492954 scopus 로고    scopus 로고
    • Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta
    • M.J. Hart, R. De los Santos, and I.N. Albert Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta Curr Biol 8 1998 573 581
    • (1998) Curr Biol , vol.8 , pp. 573-581
    • Hart, M.J.1    De Los Santos, R.2    Albert, I.N.3
  • 87
    • 0032849085 scopus 로고    scopus 로고
    • Regulation of glycogen synthase kinase 3beta and downstream Wnt signaling by axin
    • C.M. Hedgepeth, M.A. Deardorff, and K. Rankin Regulation of glycogen synthase kinase 3beta and downstream Wnt signaling by axin Mol Cell Biol 19 1999 7147 7157
    • (1999) Mol Cell Biol , vol.19 , pp. 7147-7157
    • Hedgepeth, C.M.1    Deardorff, M.A.2    Rankin, K.3
  • 88
    • 0034693230 scopus 로고    scopus 로고
    • Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling
    • V.W. Ding, R.H. Chen, and F. McCormick Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling J Biol Chem 275 2000 32475 32481
    • (2000) J Biol Chem , vol.275 , pp. 32475-32481
    • Ding, V.W.1    Chen, R.H.2    McCormick, F.3
  • 89
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • P.S. Klein, and D.A. Melton A molecular mechanism for the effect of lithium on development Proc Nat Acad Sci USA 93 1996 8455 8459
    • (1996) Proc Nat Acad Sci USA , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 90
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • S.P. Davies, H. Reddy, and M. Caivano Specificity and mechanism of action of some commonly used protein kinase inhibitors Biochem J 351 2000 95 105
    • (2000) Biochem J , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3
  • 91
    • 0030449964 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
    • V. Stambolic, L. Ruel, and J.R. Woodgett Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells Curr Biol 6 1996 1664 1668
    • (1996) Curr Biol , vol.6 , pp. 1664-1668
    • Stambolic, V.1    Ruel, L.2    Woodgett, J.R.3
  • 92
    • 0034805180 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 by competition for magnesium
    • W.J. Ryves, and A.J. Harwood Lithium inhibits glycogen synthase kinase-3 by competition for magnesium Biochem Biophys Res Commun 280 2001 720 725
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 720-725
    • Ryves, W.J.1    Harwood, A.J.2
  • 93
    • 0042379932 scopus 로고    scopus 로고
    • Lithium and GSK-3: One inhibitor, two inhibitory actions, multiple outcomes
    • R.S. Jope Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes Trends Pharmacol Sci 24 2003 441 443
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 441-443
    • Jope, R.S.1
  • 94
    • 0033587742 scopus 로고    scopus 로고
    • Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons
    • E. Chalecka-Franaszek, and D.M. Chuang Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons Proc Nat Acad Sci USA 96 1999 8745 8750
    • (1999) Proc Nat Acad Sci USA , vol.96 , pp. 8745-8750
    • Chalecka-Franaszek, E.1    Chuang, D.M.2
  • 95
    • 0036909443 scopus 로고    scopus 로고
    • Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium
    • P. De Sarno, X. Li, and R.S. Jope Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium Neuropharmacology 43 2002 1158 1164
    • (2002) Neuropharmacology , vol.43 , pp. 1158-1164
    • De Sarno, P.1    Li, X.2    Jope, R.S.3
  • 96
    • 79955024465 scopus 로고    scopus 로고
    • Lithium reduces tumorigenic potential in response to EGF signaling in human colorectal cancer cells
    • F. Vidal, W.M. de Araujo, and A.L. Cruz Lithium reduces tumorigenic potential in response to EGF signaling in human colorectal cancer cells Int J Oncol 38 2011 1365 1373
    • (2011) Int J Oncol , vol.38 , pp. 1365-1373
    • Vidal, F.1    De Araujo, W.M.2    Cruz, A.L.3
  • 97
    • 34249676180 scopus 로고    scopus 로고
    • Lithium suppresses cell proliferation by interrupting E2F-DNA interaction and subsequently reducing S-phase gene expression in prostate cancer
    • A. Sun, I. Shanmugam, and J. Song Lithium suppresses cell proliferation by interrupting E2F-DNA interaction and subsequently reducing S-phase gene expression in prostate cancer Prostate 67 2007 976 988
    • (2007) Prostate , vol.67 , pp. 976-988
    • Sun, A.1    Shanmugam, I.2    Song, J.3
  • 98
    • 53449092453 scopus 로고    scopus 로고
    • Lithium inhibits proliferation of human esophageal cancer cell line Eca-109 by inducing a G2/M cell cycle arrest
    • J.S. Wang, C.L. Wang, and J.F. Wen Lithium inhibits proliferation of human esophageal cancer cell line Eca-109 by inducing a G2/M cell cycle arrest World J Gastroenterol 14 2008 3982 3989
    • (2008) World J Gastroenterol , vol.14 , pp. 3982-3989
    • Wang, J.S.1    Wang, C.L.2    Wen, J.F.3
  • 99
    • 56149119740 scopus 로고    scopus 로고
    • Lithium inhibits invasion of glioma cells; Possible involvement of glycogen synthase kinase-3
    • M.O. Nowicki, N. Dmitrieva, and A.M. Stein Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3 Neuro Oncol 10 2008 690 699
    • (2008) Neuro Oncol , vol.10 , pp. 690-699
    • Nowicki, M.O.1    Dmitrieva, N.2    Stein, A.M.3
  • 100
    • 78650656329 scopus 로고    scopus 로고
    • Does GSK-3 provide a shortcut for PI3K activation of Wnt signalling? F1000
    • D. Voskas, L.S. Ling, and J.R. Woodgett Does GSK-3 provide a shortcut for PI3K activation of Wnt signalling? F1000 Biol Rep 2 2010 82
    • (2010) Biol Rep , vol.2 , pp. 82
    • Voskas, D.1    Ling, L.S.2    Woodgett, J.R.3
  • 101
    • 38949194936 scopus 로고    scopus 로고
    • Initiation of Wnt signaling: Control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
    • X. Zeng, H. Huang, and K. Tamai Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions Development 135 2008 367 375
    • (2008) Development , vol.135 , pp. 367-375
    • Zeng, X.1    Huang, H.2    Tamai, K.3
  • 102
    • 28644444440 scopus 로고    scopus 로고
    • Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction
    • G. Davidson, W. Wu, and J. Shen Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction Nature 438 2005 867 872
    • (2005) Nature , vol.438 , pp. 867-872
    • Davidson, G.1    Wu, W.2    Shen, J.3
  • 103
    • 28644439005 scopus 로고    scopus 로고
    • A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
    • X. Zeng, K. Tamai, and B. Doble A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation Nature 438 2005 873 877
    • (2005) Nature , vol.438 , pp. 873-877
    • Zeng, X.1    Tamai, K.2    Doble, B.3
  • 104
    • 58149185151 scopus 로고    scopus 로고
    • Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling
    • S. Piao, S.H. Lee, and H. Kim Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling PLoS ONE 3 2008 e4046
    • (2008) PLoS ONE , vol.3 , pp. 4046
    • Piao, S.1    Lee, S.H.2    Kim, H.3
  • 105
    • 62849125293 scopus 로고    scopus 로고
    • Garcia Abreu J, et al. Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6
    • G. Wu, and H. Huang Garcia Abreu J, et al. Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6 PLoS ONE 4 2009 e4926
    • (2009) PLoS ONE , vol.4 , pp. 4926
    • Wu, G.1    Huang, H.2
  • 106
    • 1642564513 scopus 로고    scopus 로고
    • A mechanism for Wnt coreceptor activation
    • K. Tamai, X. Zeng, and C. Liu A mechanism for Wnt coreceptor activation Mol Cell 13 2004 149 156
    • (2004) Mol Cell , vol.13 , pp. 149-156
    • Tamai, K.1    Zeng, X.2    Liu, C.3
  • 107
    • 0034053069 scopus 로고    scopus 로고
    • Wnt signaling in oncogenesis and embryogenesis-a look outside the nucleus
    • M. Peifer, and P. Polakis Wnt signaling in oncogenesis and embryogenesis-a look outside the nucleus Science 287 2000 1606 1609
    • (2000) Science , vol.287 , pp. 1606-1609
    • Peifer, M.1    Polakis, P.2
  • 108
    • 0029781509 scopus 로고    scopus 로고
    • Functional interaction of beta-catenin with the transcription factor LEF-1
    • J. Behrens, J.P. von Kries, and M. Kuhl Functional interaction of beta-catenin with the transcription factor LEF-1 Nature 382 1996 638 642
    • (1996) Nature , vol.382 , pp. 638-642
    • Behrens, J.1    Von Kries, J.P.2    Kuhl, M.3
  • 109
    • 0031043238 scopus 로고    scopus 로고
    • Pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila
    • E. Brunner, O. Peter, and L. Schweizer Pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila Nature 385 1997 829 833
    • (1997) Nature , vol.385 , pp. 829-833
    • Brunner, E.1    Peter, O.2    Schweizer, L.3
  • 110
    • 0030979996 scopus 로고    scopus 로고
    • LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic
    • J. Riese, X. Yu, and A. Munnerlyn LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic Cell 88 1997 777 787
    • (1997) Cell , vol.88 , pp. 777-787
    • Riese, J.1    Yu, X.2    Munnerlyn, A.3
  • 111
    • 0032483439 scopus 로고    scopus 로고
    • Identification of c-MYC as a target of the APC pathway
    • T.C. He, A.B. Sparks, and C. Rago Identification of c-MYC as a target of the APC pathway Science 281 1998 1509 1512
    • (1998) Science , vol.281 , pp. 1509-1512
    • He, T.C.1    Sparks, A.B.2    Rago, C.3
  • 112
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • O. Tetsu, and F. McCormick Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells Nature 398 1999 422 426
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 113
    • 84869210716 scopus 로고    scopus 로고
    • FoxM1 and Wnt/beta-Catenin signaling in Glioma stem cells
    • A. Gong, and S. Huang FoxM1 and Wnt/beta-Catenin signaling in Glioma stem cells Cancer Res 72 2012 5658 5662
    • (2012) Cancer Res , vol.72 , pp. 5658-5662
    • Gong, A.1    Huang, S.2
  • 114
    • 34249311572 scopus 로고    scopus 로고
    • Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines
    • B.W. Doble, S. Patel, and G.A. Wood Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines Dev Cell 12 2007 957 971
    • (2007) Dev Cell , vol.12 , pp. 957-971
    • Doble, B.W.1    Patel, S.2    Wood, G.A.3
  • 115
    • 72149109797 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase signaling does not activate the wnt cascade
    • S.S. Ng, T. Mahmoudi, and E. Danenberg Phosphatidylinositol 3-kinase signaling does not activate the wnt cascade J Biol Chem 284 2009 35308 35313
    • (2009) J Biol Chem , vol.284 , pp. 35308-35313
    • Ng, S.S.1    Mahmoudi, T.2    Danenberg, E.3
  • 116
    • 77952954695 scopus 로고    scopus 로고
    • When pathways collide: Collaboration and connivance among signalling proteins in development
    • H. McNeill, and J.R. Woodgett When pathways collide: collaboration and connivance among signalling proteins in development Nat Rev Mol Cell Biol 11 2010 404 413
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 404-413
    • McNeill, H.1    Woodgett, J.R.2
  • 117
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: Tricks of the trade for a multi-tasking kinase
    • B.W. Doble, and J.R. Woodgett GSK-3: tricks of the trade for a multi-tasking kinase J Cell Sci 116 2003 1175 1186
    • (2003) J Cell Sci , vol.116 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 118
    • 80052777490 scopus 로고    scopus 로고
    • Towards tailored therapy of glioblastoma multiforme
    • N.H. Rekers, P. Sminia, and G.J. Peters Towards tailored therapy of glioblastoma multiforme J Chemother 23 2011 187 199
    • (2011) J Chemother , vol.23 , pp. 187-199
    • Rekers, N.H.1    Sminia, P.2    Peters, G.J.3
  • 119
    • 18444399216 scopus 로고    scopus 로고
    • Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis
    • E.J. McManus, K. Sakamoto, and L.J. Armit Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis EMBO J 24 2005 1571 1583
    • (2005) EMBO J , vol.24 , pp. 1571-1583
    • McManus, E.J.1    Sakamoto, K.2    Armit, L.J.3
  • 120
    • 9244249219 scopus 로고    scopus 로고
    • APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity
    • S.H. Shi, T. Cheng, and L.Y. Jan APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity Curr Biol 14 2004 2025 2032
    • (2004) Curr Biol , vol.14 , pp. 2025-2032
    • Shi, S.H.1    Cheng, T.2    Jan, L.Y.3
  • 121
    • 0030890234 scopus 로고    scopus 로고
    • Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3
    • C.R. Beals, C.M. Sheridan, and C.W. Turck Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3 Science 275 1997 1930 1934
    • (1997) Science , vol.275 , pp. 1930-1934
    • Beals, C.R.1    Sheridan, C.M.2    Turck, C.W.3
  • 122
    • 0037092042 scopus 로고    scopus 로고
    • An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling
    • B.J. Eickholt, F.S. Walsh, and P. Doherty An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling J Cell Biol 157 2002 211 217
    • (2002) J Cell Biol , vol.157 , pp. 211-217
    • Eickholt, B.J.1    Walsh, F.S.2    Doherty, P.3
  • 123
    • 77954874401 scopus 로고    scopus 로고
    • GSK3 signalling in neural development
    • E.M. Hur, and F.Q. Zhou GSK3 signalling in neural development Nat Rev Neurosci 11 2010 539 551
    • (2010) Nat Rev Neurosci , vol.11 , pp. 539-551
    • Hur, E.M.1    Zhou, F.Q.2
  • 124
    • 0025322840 scopus 로고
    • Putative protein kinase product of the Drosophila segment-polarity gene zeste-white3
    • E. Siegfried, L.A. Perkins, and T.M. Capaci Putative protein kinase product of the Drosophila segment-polarity gene zeste-white3 Nature 345 1990 825 829
    • (1990) Nature , vol.345 , pp. 825-829
    • Siegfried, E.1    Perkins, L.A.2    Capaci, T.M.3
  • 125
    • 17644415297 scopus 로고    scopus 로고
    • Cell biology. GSK-3beta and microtubule assembly in axons
    • F.Q. Zhou, and W.D. Snider Cell biology. GSK-3beta and microtubule assembly in axons Science 308 2005 211 214
    • (2005) Science , vol.308 , pp. 211-214
    • Zhou, F.Q.1    Snider, W.D.2
  • 126
    • 7744227096 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis
    • D.A. Linseman, B.D. Butts, and T.A. Precht Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis J Neurosci 24 2004 9993 10002
    • (2004) J Neurosci , vol.24 , pp. 9993-10002
    • Linseman, D.A.1    Butts, B.D.2    Precht, T.A.3
  • 127
    • 0029855311 scopus 로고    scopus 로고
    • Protein tyrosine kinase receptors
    • C.H. Heldin Protein tyrosine kinase receptors Cancer Surv 27 1996 7 24
    • (1996) Cancer Surv , vol.27 , pp. 7-24
    • Heldin, C.H.1
  • 128
    • 0029401049 scopus 로고
    • Platelet-derived growth factor in human glioma
    • B. Westermark, C.H. Heldin, and M. Nister Platelet-derived growth factor in human glioma Glia 15 1995 257 263
    • (1995) Glia , vol.15 , pp. 257-263
    • Westermark, B.1    Heldin, C.H.2    Nister, M.3
  • 129
    • 0035479296 scopus 로고    scopus 로고
    • EGFR overexpression and radiation response in glioblastoma multiforme
    • F.G. Barker 2nd, M.L. Simmons, and S.M. Chang EGFR overexpression and radiation response in glioblastoma multiforme Int J Radiat Oncol Biol Phys 51 2001 410 418
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 410-418
    • Barker II, F.G.1    Simmons, M.L.2    Chang, S.M.3
  • 131
    • 30644463344 scopus 로고    scopus 로고
    • Overexpression of the epidermal growth factor receptor confers migratory properties to nonmigratory postnatal neural progenitors
    • A. Aguirre, T.A. Rizvi, and N. Ratner Overexpression of the epidermal growth factor receptor confers migratory properties to nonmigratory postnatal neural progenitors J Neurosci 25 2005 11092 11106
    • (2005) J Neurosci , vol.25 , pp. 11092-11106
    • Aguirre, A.1    Rizvi, T.A.2    Ratner, N.3
  • 132
    • 80053376506 scopus 로고    scopus 로고
    • CyclinD1 and cdk4 mediate development of neurologically destructive oligodendroglioma
    • D. Ciznadija, Y. Liu, and S.M. Pyonteck CyclinD1 and cdk4 mediate development of neurologically destructive oligodendroglioma Cancer Res 71 2011 6174 6183
    • (2011) Cancer Res , vol.71 , pp. 6174-6183
    • Ciznadija, D.1    Liu, Y.2    Pyonteck, S.M.3
  • 133
    • 0033944872 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase and protein kinase C attenuates extracellular matrix protein-induced vascular smooth muscle cell chemotaxis
    • A.I. Willis, S. Fuse, and X.J. Wang Inhibition of phosphatidylinositol 3-kinase and protein kinase C attenuates extracellular matrix protein-induced vascular smooth muscle cell chemotaxis J Vasc Surg 31 2000 1160 1167
    • (2000) J Vasc Surg , vol.31 , pp. 1160-1167
    • Willis, A.I.1    Fuse, S.2    Wang, X.J.3
  • 134
    • 69849089410 scopus 로고    scopus 로고
    • Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines
    • F.J. Swartling, M. Ferletta, and M. Kastemar Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines Oncogene 28 2009 3121 3131
    • (2009) Oncogene , vol.28 , pp. 3121-3131
    • Swartling, F.J.1    Ferletta, M.2    Kastemar, M.3
  • 135
    • 84855193284 scopus 로고    scopus 로고
    • Human brain glioma stem cells are more invasive than their differentiated progeny cells in vitro
    • B. Qiu, D. Zhang, and J. Tao Human brain glioma stem cells are more invasive than their differentiated progeny cells in vitro J Clin Neurosci 19 2012 130 134
    • (2012) J Clin Neurosci , vol.19 , pp. 130-134
    • Qiu, B.1    Zhang, D.2    Tao, J.3
  • 136
    • 80053135166 scopus 로고    scopus 로고
    • Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells
    • J. Hu, M. Jo, and W.K. Cavenee Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells Proc Nat Acad Sci USA 108 2011 15984 15989
    • (2011) Proc Nat Acad Sci USA , vol.108 , pp. 15984-15989
    • Hu, J.1    Jo, M.2    Cavenee, W.K.3
  • 137
    • 0028146767 scopus 로고
    • A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity
    • R. Nishikawa, X.D. Ji, and R.C. Harmon A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity Proc Nat Acad Sci USA 91 1994 7727 7731
    • (1994) Proc Nat Acad Sci USA , vol.91 , pp. 7727-7731
    • Nishikawa, R.1    Ji, X.D.2    Harmon, R.C.3
  • 138
    • 0029961912 scopus 로고    scopus 로고
    • A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis
    • M. Nagane, F. Coufal, and H. Lin A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis Cancer Res 56 1996 5079 5086
    • (1996) Cancer Res , vol.56 , pp. 5079-5086
    • Nagane, M.1    Coufal, F.2    Lin, H.3
  • 139
    • 67349137902 scopus 로고    scopus 로고
    • The EGFRvIII variant in glioblastoma multiforme
    • H.K. Gan, A.H. Kaye, and R.B. Luwor The EGFRvIII variant in glioblastoma multiforme J Clin Neurosci 16 2009 748 754
    • (2009) J Clin Neurosci , vol.16 , pp. 748-754
    • Gan, H.K.1    Kaye, A.H.2    Luwor, R.B.3
  • 140
    • 77954367523 scopus 로고    scopus 로고
    • EGFR signaling is differentially activated in patient-derived glioblastoma stem cells
    • B.M. Howard, D.B. Gursel, and A.M. Bleau EGFR signaling is differentially activated in patient-derived glioblastoma stem cells J Exp Therapeut Oncol 8 2010 247 260
    • (2010) J Exp Therapeut Oncol , vol.8 , pp. 247-260
    • Howard, B.M.1    Gursel, D.B.2    Bleau, A.M.3
  • 141
    • 0034987702 scopus 로고    scopus 로고
    • Malignant glioma: Genetics and biology of a grave matter
    • E.A. Maher, F.B. Furnari, and R.M. Bachoo Malignant glioma: genetics and biology of a grave matter Genes Dev 15 2001 1311 1333
    • (2001) Genes Dev , vol.15 , pp. 1311-1333
    • Maher, E.A.1    Furnari, F.B.2    Bachoo, R.M.3
  • 142
    • 0030778206 scopus 로고    scopus 로고
    • Molecular changes during the genesis of human gliomas
    • A. Sehgal Molecular changes during the genesis of human gliomas Semin Surg Oncol 14 1998 3 12
    • (1998) Semin Surg Oncol , vol.14 , pp. 3-12
    • Sehgal, A.1
  • 143
    • 53049093524 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulation
    • S. Kotliarova, S. Pastorino, and L.C. Kovell Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulation Cancer Res 68 2008 6643 6651
    • (2008) Cancer Res , vol.68 , pp. 6643-6651
    • Kotliarova, S.1    Pastorino, S.2    Kovell, L.C.3
  • 144
    • 65749087298 scopus 로고    scopus 로고
    • Neurosphere formation is an independent predictor of clinical outcome in malignant glioma
    • D.R. Laks, M. Masterman-Smith, and K. Visnyei Neurosphere formation is an independent predictor of clinical outcome in malignant glioma Stem Cells 27 2009 980 987
    • (2009) Stem Cells , vol.27 , pp. 980-987
    • Laks, D.R.1    Masterman-Smith, M.2    Visnyei, K.3
  • 145
    • 84863382046 scopus 로고    scopus 로고
    • Interleukin-1beta and transforming growth factor-beta cooperate to induce neurosphere formation and increase tumorigenicity of adherent LN-229 glioma cells
    • L. Wang, Z. Liu, and S. Balivada Interleukin-1beta and transforming growth factor-beta cooperate to induce neurosphere formation and increase tumorigenicity of adherent LN-229 glioma cells Stem Cell Res Ther 3 2012 5
    • (2012) Stem Cell Res Ther , vol.3 , pp. 5
    • Wang, L.1    Liu, Z.2    Balivada, S.3
  • 146
    • 77951247981 scopus 로고    scopus 로고
    • Frequent promoter hypermethylation of Wnt pathway inhibitor genes in malignant astrocytic gliomas
    • S. Gotze, M. Wolter, and G. Reifenberger Frequent promoter hypermethylation of Wnt pathway inhibitor genes in malignant astrocytic gliomas Int J Cancer (J Int Du Cancer) 126 2010 2584 2593
    • (2010) Int J Cancer (J Int du Cancer) , vol.126 , pp. 2584-2593
    • Gotze, S.1    Wolter, M.2    Reifenberger, G.3
  • 147
    • 61349146623 scopus 로고    scopus 로고
    • Potential therapeutic effect of glycogen synthase kinase 3beta inhibition against human glioblastoma
    • K. Miyashita, K. Kawakami, and M. Nakada Potential therapeutic effect of glycogen synthase kinase 3beta inhibition against human glioblastoma Clin Cancer Res 15 2009 887 897
    • (2009) Clin Cancer Res , vol.15 , pp. 887-897
    • Miyashita, K.1    Kawakami, K.2    Nakada, M.3
  • 148
    • 77955146804 scopus 로고    scopus 로고
    • Podosome-like structures of non-invasive carcinoma cells are replaced in epithelial-mesenchymal transition by actin comet-embedded invadopodia
    • M. Takkunen, M. Hukkanen, and M. Liljestrom Podosome-like structures of non-invasive carcinoma cells are replaced in epithelial-mesenchymal transition by actin comet-embedded invadopodia J Cell Mol Med 14 2010 1569 1593
    • (2010) J Cell Mol Med , vol.14 , pp. 1569-1593
    • Takkunen, M.1    Hukkanen, M.2    Liljestrom, M.3
  • 149
    • 44249097734 scopus 로고    scopus 로고
    • Invadopodia: At the cutting edge of tumour invasion
    • S.S. Stylli, A.H. Kaye, and P. Lock Invadopodia: at the cutting edge of tumour invasion Journal Clin Neurosci 15 2008 725 737
    • (2008) Journal Clin Neurosci , vol.15 , pp. 725-737
    • Stylli, S.S.1    Kaye, A.H.2    Lock, P.3
  • 150
    • 84856762203 scopus 로고    scopus 로고
    • Prognostic significance of Tks5 expression in gliomas
    • S.S. Stylli, I. ST, and A.H. Kaye Prognostic significance of Tks5 expression in gliomas J Clin Neurosci 19 2012 436 442
    • (2012) J Clin Neurosci , vol.19 , pp. 436-442
    • Stylli, S.S.1    St, I.2    Kaye, A.H.3
  • 151
    • 0032030894 scopus 로고    scopus 로고
    • Sporadic medulloblastomas contain oncogenic beta-catenin mutations
    • R.H. Zurawel, S.A. Chiappa, and C. Allen Sporadic medulloblastomas contain oncogenic beta-catenin mutations Cancer Res 58 1998 896 899
    • (1998) Cancer Res , vol.58 , pp. 896-899
    • Zurawel, R.H.1    Chiappa, S.A.2    Allen, C.3
  • 152
    • 0028970197 scopus 로고
    • The molecular basis of Turcot's syndrome
    • S.R. Hamilton, B. Liu, and R.E. Parsons The molecular basis of Turcot's syndrome N Engl J Med 332 1995 839 847
    • (1995) N Engl J Med , vol.332 , pp. 839-847
    • Hamilton, S.R.1    Liu, B.2    Parsons, R.E.3
  • 153
    • 18744398990 scopus 로고    scopus 로고
    • Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling
    • M.F. Kielman, M. Rindapaa, and C. Gaspar Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling Nat Genet 32 2002 594 605
    • (2002) Nat Genet , vol.32 , pp. 594-605
    • Kielman, M.F.1    Rindapaa, M.2    Gaspar, C.3
  • 154
    • 66349110796 scopus 로고    scopus 로고
    • Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma
    • R.J. Ward, L. Lee, and K. Graham Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma Cancer Res 69 2009 4682 4690
    • (2009) Cancer Res , vol.69 , pp. 4682-4690
    • Ward, R.J.1    Lee, L.2    Graham, K.3
  • 155
    • 34247849227 scopus 로고    scopus 로고
    • Common strategy for adult and pediatric medulloblastoma: A multicenter series of 253 adults
    • L. Padovani, M.P. Sunyach, and D. Perol Common strategy for adult and pediatric medulloblastoma: a multicenter series of 253 adults Int J Radiat Oncol Biol Phys 68 2007 433 440
    • (2007) Int J Radiat Oncol Biol Phys , vol.68 , pp. 433-440
    • Padovani, L.1    Sunyach, M.P.2    Perol, D.3
  • 156
    • 84867679540 scopus 로고    scopus 로고
    • Long-term survival of patients suffering from glioblastoma multiforme treated with tumortreating fields
    • A.M. Rulseh, J.I. Keller, and J. Klener Long-term survival of patients suffering from glioblastoma multiforme treated with tumortreating fields World J Surg Oncol 10 2012 220
    • (2012) World J Surg Oncol , vol.10 , pp. 220
    • Rulseh, A.M.1    Keller, J.I.2    Klener, J.3
  • 157
    • 80053565518 scopus 로고    scopus 로고
    • Phase 2 trial of temozolomide and pegylated liposomal doxorubicin in the treatment of patients with glioblastoma multiforme following concurrent radiotherapy and chemotherapy
    • S. Ananda, A.K. Nowak, and L. Cher Phase 2 trial of temozolomide and pegylated liposomal doxorubicin in the treatment of patients with glioblastoma multiforme following concurrent radiotherapy and chemotherapy J Clin Neurosci 18 2011 1444 1448
    • (2011) J Clin Neurosci , vol.18 , pp. 1444-1448
    • Ananda, S.1    Nowak, A.K.2    Cher, L.3
  • 158
    • 77649100933 scopus 로고    scopus 로고
    • Targeting A20 decreases glioma stem cell survival and tumor growth
    • A.B. Hjelmeland, Q. Wu, and S. Wickman Targeting A20 decreases glioma stem cell survival and tumor growth PLoS Biol 8 2010 e1000319
    • (2010) PLoS Biol , vol.8 , pp. 1000319
    • Hjelmeland, A.B.1    Wu, Q.2    Wickman, S.3
  • 159
    • 0031809141 scopus 로고    scopus 로고
    • Cancer morbidity in psychiatric patients: Influence of lithium carbonate treatment
    • Y. Cohen, A. Chetrit, and Y. Cohen Cancer morbidity in psychiatric patients: influence of lithium carbonate treatment Med Oncol 15 1998 32 36
    • (1998) Med Oncol , vol.15 , pp. 32-36
    • Cohen, Y.1    Chetrit, A.2    Cohen, Y.3
  • 160
    • 67650886050 scopus 로고    scopus 로고
    • Cytoplasmic accumulation of glycogen synthase kinase-3beta is associated with aggressive clinicopathological features in human prostate cancer
    • R. Li, S. Erdamar, and H. Dai Cytoplasmic accumulation of glycogen synthase kinase-3beta is associated with aggressive clinicopathological features in human prostate cancer Anticancer Res. 29 2009 2077 2081
    • (2009) Anticancer Res. , vol.29 , pp. 2077-2081
    • Li, R.1    Erdamar, S.2    Dai, H.3
  • 161
    • 0036024549 scopus 로고    scopus 로고
    • Expression of cyclin D1 and GSK-3beta and their predictive value of prognosis in squamous cell carcinomas of the tongue
    • H. Goto, K. Kawano, and I. Kobayashi Expression of cyclin D1 and GSK-3beta and their predictive value of prognosis in squamous cell carcinomas of the tongue Oral Oncol. 38 2002 549 556
    • (2002) Oral Oncol. , vol.38 , pp. 549-556
    • Goto, H.1    Kawano, K.2    Kobayashi, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.