메뉴 건너뛰기




Volumn 56, Issue 21, 1996, Pages 5079-5086

A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; EPIDERMAL GROWTH FACTOR RECEPTOR; MONOCLONAL ANTIBODY KI 67;

EID: 0029961912     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (375)

References (44)
  • 3
    • 0029094065 scopus 로고
    • A tiger behind many doors multiple genetic pathways to malignant glioma
    • Louis, D. N., and Gusella, J. F. A tiger behind many doors multiple genetic pathways to malignant glioma. Trends Genet., 11: 412-415, 1995.
    • (1995) Trends Genet. , vol.11 , pp. 412-415
    • Louis, D.N.1    Gusella, J.F.2
  • 7
    • 0026521394 scopus 로고
    • Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails
    • Ekstrand, A. J., Sugawa, N., James, C. D., and Collins, V. P. Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails. Proc. Natl. Acad. Sci. USA, 89: 4309-4313, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4309-4313
    • Ekstrand, A.J.1    Sugawa, N.2    James, C.D.3    Collins, V.P.4
  • 8
    • 0023663896 scopus 로고
    • Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells
    • Di, F. P., Pierce, J. H. Fleming, T. P., Hazan, R., Ullrich, A., King, C. R., Schlessinger, J., and Aaronson, S. A. Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells. Cell, 51: 1063-1070, 1987.
    • (1987) Cell , vol.51 , pp. 1063-1070
    • Di, F.P.1    Pierce, J.H.2    Fleming, T.P.3    Hazan, R.4    Ullrich, A.5    King, C.R.6    Schlessinger, J.7    Aaronson, S.A.8
  • 10
    • 0023949462 scopus 로고
    • Amplified and overexpressed epidermal growth factor receptor gene in uncultured primary human breast carcinoma
    • Ro, J., North, S. M., Gallick, G. E., Hortobagyi, G. N., Gutterman, J. U., and Blick, M. Amplified and overexpressed epidermal growth factor receptor gene in uncultured primary human breast carcinoma. Cancer Res., 48: 161-164, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 161-164
    • Ro, J.1    North, S.M.2    Gallick, G.E.3    Hortobagyi, G.N.4    Gutterman, J.U.5    Blick, M.6
  • 12
    • 0021705725 scopus 로고
    • Characterization of epidermal growth factor receptor gene expression in malignant and normal human cell lines
    • Xu, Y. H., Richert, N., Ito, S., Merlino, G. T., and Pastan, I. Characterization of epidermal growth factor receptor gene expression in malignant and normal human cell lines. Proc. Natl. Acad. Sci. USA, 81: 7308-7312, 1984.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 7308-7312
    • Xu, Y.H.1    Richert, N.2    Ito, S.3    Merlino, G.T.4    Pastan, I.5
  • 13
    • 0021932290 scopus 로고
    • Hyperproduction and gene amplification of the epidermal growth factor receptor in squamous cell carcinomas
    • Hunts, J., Ueda, M., Ozawa, S., Abe, O., Pastan, I., and Shimizu, N. Hyperproduction and gene amplification of the epidermal growth factor receptor in squamous cell carcinomas. Jpn. J. Cancer Res., 76: 663-666, 1985.
    • (1985) Jpn. J. Cancer Res. , vol.76 , pp. 663-666
    • Hunts, J.1    Ueda, M.2    Ozawa, S.3    Abe, O.4    Pastan, I.5    Shimizu, N.6
  • 15
    • 0028097815 scopus 로고
    • Amplification of the epidermal-growth-factor-receptor gene correlates with different growth behaviour in human ghoblastoma
    • Schlegel, J., Merdes, A., Stumm, G., Albert, F. K., Forsting, M., Hynes, N., and Kiessling, M. Amplification of the epidermal-growth-factor-receptor gene correlates with different growth behaviour in human ghoblastoma. Int. J. Cancer, 56: 72-77, 1994.
    • (1994) Int. J. Cancer , vol.56 , pp. 72-77
    • Schlegel, J.1    Merdes, A.2    Stumm, G.3    Albert, F.K.4    Forsting, M.5    Hynes, N.6    Kiessling, M.7
  • 16
    • 0025790916 scopus 로고
    • Genes for epidermal growth factor receptor, transforming growth factor α, and epidermal growth factor and their expression in human gliomas in vivo
    • Ekstrand, A. J., James, C. D., Cavenee, W. K., Seliger, B., Petterson, R. F., and Collins, V. P. Genes for epidermal growth factor receptor, transforming growth factor α, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res., 51: 2164-2172, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 2164-2172
    • Ekstrand, A.J.1    James, C.D.2    Cavenee, W.K.3    Seliger, B.4    Petterson, R.F.5    Collins, V.P.6
  • 17
    • 0025114687 scopus 로고
    • Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas
    • Sugawa, N., Ekstrand, A. J., James, C. D., and Collins, V. P. Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas. Proc. Natl. Acad. Sci. USA, 87: 8602-8606, 1990.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8602-8606
    • Sugawa, N.1    Ekstrand, A.J.2    James, C.D.3    Collins, V.P.4
  • 19
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Washington DC
    • Nowell, P. C. The clonal evolution of tumor cell populations. Science (Washington DC), 194: 23-28, 1976.
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 20
    • 0021978223 scopus 로고
    • Tumor angiogenesis
    • Folkman, J. Tumor angiogenesis. Adv. Cancer Res., 43: 175-203, 1985.
    • (1985) Adv. Cancer Res. , vol.43 , pp. 175-203
    • Folkman, J.1
  • 21
    • 0028231893 scopus 로고
    • Apoptosis is inversely related to necrosis and determines net growth in tumors bearing constitutively expressed myc, ras, and HPV oncogenes
    • Arends, M. J., McGregor, A. H., and Wyllie, A. H. Apoptosis is inversely related to necrosis and determines net growth in tumors bearing constitutively expressed myc, ras, and HPV oncogenes. Am. J. Pathol., 144: 1045-1057, 1994.
    • (1994) Am. J. Pathol. , vol.144 , pp. 1045-1057
    • Arends, M.J.1    McGregor, A.H.2    Wyllie, A.H.3
  • 22
    • 0028329172 scopus 로고
    • Apoptosis. Its significance in cancer and cancer therapy
    • Phila.
    • Kerr, J. F., Winterford, C. M., and Harmon, B. V. Apoptosis. Its significance in cancer and cancer therapy. Cancer (Phila.), 73: 2013-2026, 1994.
    • (1994) Cancer , vol.73 , pp. 2013-2026
    • Kerr, J.F.1    Winterford, C.M.2    Harmon, B.V.3
  • 23
    • 0028862261 scopus 로고
    • Detection of DNA strand breaks associated with apoptosis in human brain tumors
    • Nakagawa, S., Shiraishi, T., Kihara, S., and Tabuchi, K. Detection of DNA strand breaks associated with apoptosis in human brain tumors. Virchows Arch., 427: 175-179, 1995.
    • (1995) Virchows Arch. , vol.427 , pp. 175-179
    • Nakagawa, S.1    Shiraishi, T.2    Kihara, S.3    Tabuchi, K.4
  • 25
    • 0014364322 scopus 로고
    • Long term culture of normal and neoplastic human glia
    • Ponten, J., and Macintyre, E. H. Long term culture of normal and neoplastic human glia. Acta Pathol. Microbiol. Scand., 74: 465-486, 1968.
    • (1968) Acta Pathol. Microbiol. Scand. , vol.74 , pp. 465-486
    • Ponten, J.1    Macintyre, E.H.2
  • 26
    • 0026546830 scopus 로고
    • A recombinant retrovirus encoding alkaline phosphatase confirms clonal boundary assignment in lineage analysis of murine retina
    • Fields-Berry, S. C., Halliday, A. L., and Cepko, C. L. A recombinant retrovirus encoding alkaline phosphatase confirms clonal boundary assignment in lineage analysis of murine retina. Proc. Natl. Acad. Sci. USA, 89: 693-697, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 693-697
    • Fields-Berry, S.C.1    Halliday, A.L.2    Cepko, C.L.3
  • 27
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli, Y., Sherman, Y., and Ben-Sasson, S. A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation J. Cell. Biol., 119: 493-501, 1992.
    • (1992) J. Cell. Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 28
    • 0023967439 scopus 로고
    • Rapid, reversible staining of northern blots prior to hybridization
    • Herrin, D. L. and Schmidt, G. W. Rapid, reversible staining of northern blots prior to hybridization. Biotechniques, 6: 196-200, 1988.
    • (1988) Biotechniques , vol.6 , pp. 196-200
    • Herrin, D.L.1    Schmidt, G.W.2
  • 29
    • 0021212003 scopus 로고
    • Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67
    • Gerdes, J., Lemke, H., Baisch, H., Wacker, H. H., Schwab, U., and Stein, H. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J. Immunol., 133: 1710-1715, 1984.
    • (1984) J. Immunol. , vol.133 , pp. 1710-1715
    • Gerdes, J.1    Lemke, H.2    Baisch, H.3    Wacker, H.H.4    Schwab, U.5    Stein, H.6
  • 30
    • 0022263122 scopus 로고
    • Immunocytochemical demonstration of S-phase cells by anti-bromodeoxyuridine monoclonal antibody in human brain tumor tissues
    • Nagashima, T., DeArmond, S. J., Murovic, J., and Hoshino, T. Immunocytochemical demonstration of S-phase cells by anti-bromodeoxyuridine monoclonal antibody in human brain tumor tissues. Acta Neuropathol., 67: 155-159, 1985.
    • (1985) Acta Neuropathol. , vol.67 , pp. 155-159
    • Nagashima, T.1    DeArmond, S.J.2    Murovic, J.3    Hoshino, T.4
  • 31
    • 0027461601 scopus 로고
    • Prognostic significance of the proliferative potential of intracranial gliomas measured by bromodcoxyuridine labeling
    • Hoshino, T., Ahn, D., Prados, M. D., Lamborn, K., and Wilson, C. B. Prognostic significance of the proliferative potential of intracranial gliomas measured by bromodcoxyuridine labeling. Int. J. Cancer, 53: 550-555, 1993.
    • (1993) Int. J. Cancer , vol.53 , pp. 550-555
    • Hoshino, T.1    Ahn, D.2    Prados, M.D.3    Lamborn, K.4    Wilson, C.B.5
  • 32
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed, J. C. Bcl-2 and the regulation of programmed cell death J. Cell. Biol., 124: 1-6, 1994.
    • (1994) J. Cell. Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 33
    • 0013543749 scopus 로고
    • Transforming growth factors produced by certain human tumor cells: Polypeptides that interact with epidermal growth factor receptors
    • Todaro, G. J., Fryling, C., and De Larco, J. E. Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors. Proc. Natl. Acad. Sci. USA, 77: 5258-5262, 1980.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 5258-5262
    • Todaro, G.J.1    Fryling, C.2    De Larco, J.E.3
  • 34
    • 0025139326 scopus 로고
    • Ligand-induced transformation by a noninternalizing epidermal growth factor receptor
    • Washington DC
    • Wells, A., Welsh, J. B., Lazar, C. S., Wiley, H. S., Gill, G. N., and Rosenfeld, M. G. Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. Science (Washington DC), 247: 962-964, 1990.
    • (1990) Science , vol.247 , pp. 962-964
    • Wells, A.1    Welsh, J.B.2    Lazar, C.S.3    Wiley, H.S.4    Gill, G.N.5    Rosenfeld, M.G.6
  • 35
    • 0028916337 scopus 로고
    • Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain
    • Opresko, L. K., Chang, C. P., Will, B. H., Burke, P. M., Gill, G. N., and Wiley, H. S. Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain. J. Biol. Chem., 270: 4325-4333, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4325-4333
    • Opresko, L.K.1    Chang, C.P.2    Will, B.H.3    Burke, P.M.4    Gill, G.N.5    Wiley, H.S.6
  • 37
    • 0021254281 scopus 로고
    • Actual growth rate and tumour cell proliferation in human pulmonary neoplasms
    • Kerr, K. M., and Lamb, D. Actual growth rate and tumour cell proliferation in human pulmonary neoplasms. Br. J. Cancer, 50: 343-349, 1984.
    • (1984) Br. J. Cancer , vol.50 , pp. 343-349
    • Kerr, K.M.1    Lamb, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.