-
1
-
-
0019982538
-
The role of protein phosphorylation in neural and hormonal control of cellular activity
-
Cohen, P. The role of protein phosphorylation in neural and hormonal control of cellular activity. Nature 296, 613-620 (1982).
-
(1982)
Nature
, vol.296
, pp. 613-620
-
-
Cohen, P.1
-
2
-
-
70349932747
-
Towards an integrated view of Wnt signaling in development
-
van Amerongen, R. & Nusse, R. Towards an integrated view of Wnt signaling in development. Development 136, 3205-3214 (2009).
-
(2009)
Development
, vol.136
, pp. 3205-3214
-
-
Van Amerongen, R.1
Nusse, R.2
-
3
-
-
67650230896
-
Wnt/β-catenin signaling: Components, mechanisms, and diseases
-
MacDonald, B. T., Tamai, K. & He, X. Wnt/β-catenin signaling: components, mechanisms, and diseases. Dev. Cell 17, 9-26 (2009).
-
(2009)
Dev. Cell
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
4
-
-
57049097531
-
The Hippo-YAP pathway: New connections between regulation of organ size and cancer
-
Zhao, B., Lei, Q. Y. & Guan, K. L. The Hippo-YAP pathway: new connections between regulation of organ size and cancer. Curr. Opin. Cell Biol. 20, 638-646 (2008).
-
(2008)
Curr. Opin. Cell Biol.
, vol.20
, pp. 638-646
-
-
Zhao, B.1
Lei, Q.Y.2
Guan, K.L.3
-
5
-
-
39849097306
-
The emerging role of the Hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals
-
Zeng, Q. & Hong, W. The emerging role of the Hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals. Cancer Cell 13, 188-192 (2008).
-
(2008)
Cancer Cell
, vol.13
, pp. 188-192
-
-
Zeng, Q.1
Hong, W.2
-
6
-
-
0028568147
-
Signaling by wingless in drosophila
-
Klingensmith, J. & Nusse, R. Signaling by Wingless in Drosophila. Dev. Biol. 166, 396-414 (1994).
-
(1994)
Dev. Biol.
, vol.166
, pp. 396-414
-
-
Klingensmith, J.1
Nusse, R.2
-
7
-
-
34249061491
-
Wilms tumor suppressor WTX negatively regulates WNT/β-catenin signaling
-
Major, M. B. et al. Wilms tumor suppressor WTX negatively regulates WNT/β-catenin signaling. Science 316, 1043-1046 (2007).
-
(2007)
Science
, vol.316
, pp. 1043-1046
-
-
Major, M.B.1
-
8
-
-
73149084197
-
Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway
-
Miller, B. W. et al. Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway. Mol. Syst. Biol. 5, 315 (2009).
-
(2009)
Mol. Syst. Biol.
, vol.5
, pp. 315
-
-
Miller, B.W.1
-
9
-
-
62849106337
-
β-catenin hits chromatin: Regulation of Wnt target gene activation
-
Mosimann, C., Hausmann, G. & Basler, K. β-catenin hits chromatin: regulation of Wnt target gene activation. Nature Rev. Mol. Cell Biol. 10, 276-286 (2009).
-
(2009)
Nature Rev. Mol. Cell Biol.
, vol.10
, pp. 276-286
-
-
Mosimann, C.1
Hausmann, G.2
Basler, K.3
-
10
-
-
0036148208
-
Wnt/β-catenin/TCF signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
-
Jho, E. H. et al. Wnt/β-catenin/TCF signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol. Cell. Biol. 22, 1172-1183 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1172-1183
-
-
Jho, E.H.1
-
11
-
-
4243067196
-
The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway
-
Lee, E., Salic, A., Kruger, R., Heinrich, R. & Kirschner, M. W. The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. PLoS Biol. 1, E10 (2003).
-
(2003)
PLoS Biol.
, vol.1
-
-
Lee, E.1
Salic, A.2
Kruger, R.3
Heinrich, R.4
Kirschner, M.W.5
-
12
-
-
42149131539
-
Adenomatous polyposis coli is present near the minimal level required for accurate graded responses to the Wingless morphogen
-
Benchabane, H., Hughes, E. G., Takacs, C. M., Baird, J. R. & Ahmed, Y. Adenomatous polyposis coli is present near the minimal level required for accurate graded responses to the Wingless morphogen. Development 135, 963-971 (2008).
-
(2008)
Development
, vol.135
, pp. 963-971
-
-
Benchabane, H.1
Hughes, E.G.2
Takacs, C.M.3
Baird, J.R.4
Ahmed, Y.5
-
13
-
-
33846193290
-
The many ways of Wnt in cancer
-
Polakis, P. The many ways of Wnt in cancer. Curr. Opin. Genet. Dev. 17, 45-51 (2007).
-
(2007)
Curr. Opin. Genet. Dev.
, vol.17
, pp. 45-51
-
-
Polakis, P.1
-
14
-
-
34249311572
-
Functional redundancy of GSK-3a and GSK-3(3 in Wnt/p-catenin signaling shown by using an allelic series of embryonic stem cell lines
-
Doble, B. W, Patel, S., Wood, G. A., Kockeritz, L. K. & Woodgett, J. R. Functional redundancy of GSK-3a and GSK-3(3 in Wnt/p-catenin signaling shown by using an allelic series of embryonic stem cell lines. Dev. Cell 12, 957-971 (2007).
-
(2007)
Dev. Cell
, vol.12
, pp. 957-971
-
-
Doble, B.W.1
Patel, S.2
Wood, G.A.3
Kockeritz, L.K.4
Woodgett, J.R.5
-
16
-
-
28644444440
-
Casein kinase 1 y couples Wnt receptor activation to cytoplasmic signal transduction
-
Davidson, G. et al. Casein kinase 1 y couples Wnt receptor activation to cytoplasmic signal transduction. Nature 438, 867-872 (2005).
-
(2005)
Nature
, vol.438
, pp. 867-872
-
-
Davidson, G.1
-
17
-
-
28644439005
-
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
-
Zeng, X. et al. A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature 438, 873-877 (2005).
-
(2005)
Nature
, vol.438
, pp. 873-877
-
-
Zeng, X.1
-
18
-
-
38949194936
-
Initiation of Wnt signaling: Control of Wnt coreceptor LRP6 phosphorylation/activation via Frizzled Dishevelled and Axin functions
-
Zeng, X. et al. Initiation of Wnt signaling: control of Wnt coreceptor LRP6 phosphorylation/activation via Frizzled, Dishevelled and Axin functions. Development 135, 367-375 (2008).
-
(2008)
Development
, vol.135
, pp. 367-375
-
-
Zeng, X.1
-
19
-
-
38349083255
-
Dual positive and negative regulation of Wingless signaling by Adenomatous polyposis coli
-
Takacs, C. M. et al. Dual positive and negative regulation of Wingless signaling by Adenomatous polyposis coli. Science 319, 333-336 (2008).
-
(2008)
Science
, vol.319
, pp. 333-336
-
-
Takacs, C.M.1
-
20
-
-
18444399216
-
Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis
-
McManus, E. J. et al. Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis. EMBO J. 24, 1571-1583 (2005).
-
(2005)
EMBO J.
, vol.24
, pp. 1571-1583
-
-
McManus, E.J.1
-
21
-
-
72149109797
-
Phosphatidylinositol 3-kinase signaling does not activate the Wnt cascade
-
Ng, S. S. et al. Phosphatidylinositol 3-kinase signaling does not activate the Wnt cascade. J. Biol. Chem. 284, 35308-35313 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 35308-35313
-
-
Ng, S.S.1
-
22
-
-
0029768676
-
An in vivo structure-function study of Armadillo, the β-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for Wingless signaling
-
Orsulic, S. & Peifer, M. An in vivo structure-function study of Armadillo, the β-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for Wingless signaling. J. Cell Biol. 134, 1283-1300 (1996).
-
(1996)
J. Cell Biol.
, vol.134
, pp. 1283-1300
-
-
Orsulic, S.1
Peifer, M.2
-
23
-
-
58149185543
-
Planar cell polarity signaling: From fly development to human disease
-
Simons, M. & Mlodzik, M. Planar cell polarity signaling: from fly development to human disease. Annu. Rev. Genet. 42, 517-540 (2008).
-
(2008)
Annu. Rev. Genet.
, vol.42
, pp. 517-540
-
-
Simons, M.1
Mlodzik, M.2
-
24
-
-
44649101853
-
Asymmetric homotypic interactions of the atypical cadherin Flamingo mediate intercellular polarity signaling
-
Chen, W. S. et al. Asymmetric homotypic interactions of the atypical cadherin Flamingo mediate intercellular polarity signaling. Cell 133, 1093-1105 (2008).
-
(2008)
Cell
, vol.133
, pp. 1093-1105
-
-
Chen, W.S.1
-
25
-
-
0036333367
-
Towards a model of the organisation of planar polarity and pattern in the Drosophila abdomen
-
Lawrence, P. A., Casal, J. & Struhl, G. Towards a model of the organisation of planar polarity and pattern in the Drosophila abdomen. Development 129, 2749-2760 (2002).
-
(2002)
Development
, vol.129
, pp. 2749-2760
-
-
Lawrence, P.A.1
Casal, J.2
Struhl, G.3
-
26
-
-
0037162283
-
Developmental compartments and planar polarity in Drosophila
-
Casal, J., Struhl, G. & Lawrence, P. A. Developmental compartments and planar polarity in Drosophila. Curr. Biol. 12, 1189-1198 (2002).
-
(2002)
Curr. Biol.
, vol.12
, pp. 1189-1198
-
-
Casal, J.1
Struhl, G.2
Lawrence, P.A.3
-
27
-
-
0037172663
-
The cadherins Fat and Dachsous regulate dorsal/ventral signaling in the Drosophila eye
-
Rawls, A. S., Guinto, J. B. & Wolff, T. The cadherins Fat and Dachsous regulate dorsal/ventral signaling in the Drosophila eye. Curr. Biol. 12, 1021-1026 (2002).
-
(2002)
Curr. Biol.
, vol.12
, pp. 1021-1026
-
-
Rawls, A.S.1
Guinto, J.B.2
Wolff, T.3
-
28
-
-
0037040407
-
Regulation of Frizzled by Fat-like cadherins during planar polarity signaling in the Drosophila compound eye
-
Yang, C. H., Axelrod, J. D. & Simon, M. A. Regulation of Frizzled by Fat-like cadherins during planar polarity signaling in the Drosophila compound eye. Cell 108, 675-688 (2002).
-
(2002)
Cell
, vol.108
, pp. 675-688
-
-
Yang, C.H.1
Axelrod, J.D.2
Simon, M.A.3
-
29
-
-
48349125616
-
Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease
-
Saburi, S. et al. Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nature Genet. 40, 1010-1015 (2008).
-
(2008)
Nature Genet.
, vol.40
, pp. 1010-1015
-
-
Saburi, S.1
-
30
-
-
33845288905
-
Tw o separate molecular systems, Dachsous/Fat and Starry night/Frizzled, act independently to confer planar cell polarity
-
Casal, J., Lawrence, P. A. & Struhl, G. Tw o separate molecular systems, Dachsous/Fat and Starry night/Frizzled, act independently to confer planar cell polarity. Development 133, 4561-4572 (2006).
-
(2006)
Development
, vol.133
, pp. 4561-4572
-
-
Casal, J.1
Lawrence, P.A.2
Struhl, G.3
-
31
-
-
70349338886
-
The skinny on Fat: An enormous cadherin that regulates cell adhesion, tissue growth, and planar cell polarity
-
Sopko, R. & McNeill, H. The skinny on Fat: an enormous cadherin that regulates cell adhesion, tissue growth, and planar cell polarity. Curr. Opin. Cell Biol. 21, 717-723 (2009).
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 717-723
-
-
Sopko, R.1
McNeill, H.2
-
32
-
-
0037324628
-
The tumor-suppressor and cell adhesion molecule Fat controls planar polarity via physical interactions with Atrophin, a transcriptional co-repressor
-
Fanto, M. et al. The tumor-suppressor and cell adhesion molecule Fat controls planar polarity via physical interactions with Atrophin, a transcriptional co-repressor. Development 130, 763-774 (2003).
-
(2003)
Development
, vol.130
, pp. 763-774
-
-
Fanto, M.1
-
33
-
-
4444240972
-
Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing
-
Matakatsu, H. & Blair, S. S. Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing. Development 131, 3785-3794 (2004).
-
(2004)
Development
, vol.131
, pp. 3785-3794
-
-
Matakatsu, H.1
Blair, S.S.2
-
34
-
-
12344251185
-
Planar cell polarity in the Drosophila eye is directed by graded Four-jointed and Dachsous expression
-
Simon, M. A. Planar cell polarity in the Drosophila eye is directed by graded Four-jointed and Dachsous expression. Development 131, 6175-6184 (2004).
-
(2004)
Development
, vol.131
, pp. 6175-6184
-
-
Simon, M.A.1
-
35
-
-
69749095888
-
Convergence and extension movements during vertebrate gastrulation
-
Yin, C., Ciruna, B. & Solnica-Krezel, L. Convergence and extension movements during vertebrate gastrulation. Curr. Top. Dev. Biol. 89, 163-192 (2009).
-
(2009)
Curr. Top. Dev. Biol.
, vol.89
, pp. 163-192
-
-
Yin, C.1
Ciruna, B.2
Solnica-Krezel, L.3
-
36
-
-
0028929367
-
Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos
-
Du, S. J., Purcell, S. M., Christian, J. L., McGrew, L. L. & Moon, R. T. Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos. Mol. Cell. Biol. 15, 2625-2634 (1995).
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2625-2634
-
-
Du, S.J.1
Purcell, S.M.2
Christian, J.L.3
McGrew, L.L.4
Moon, R.T.5
-
37
-
-
0027965236
-
Differential transformation of mammary epithelial cells by Wnt genes
-
Wong, G. T., Gavin, B. J. & McMahon, A. P. Differential transformation of mammary epithelial cells by Wnt genes. Mol. Cell. Biol. 14, 6278-6286 (1994).
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6278-6286
-
-
Wong, G.T.1
Gavin, B.J.2
McMahon, A.P.3
-
38
-
-
67649470380
-
Proximal events in Wnt signal transduction
-
Angers, S. & Moon, R. T. Proximal events in Wnt signal transduction. Nature Rev. Mol. Cell Biol. 10, 468-477 (2009).
-
(2009)
Nature Rev. Mol. Cell Biol.
, vol.10
, pp. 468-477
-
-
Angers, S.1
Moon, R.T.2
-
39
-
-
0029939701
-
Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development
-
Torres, M. A. et al. Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development. J. Cell Biol. 133, 1123-1137 (1996).
-
(1996)
J. Cell Biol.
, vol.133
, pp. 1123-1137
-
-
Torres, M.A.1
-
40
-
-
0033600239
-
The TAK1-NLK-MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF
-
Ishitani, T. et al. The TAK1-NLK-MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF. Nature 399, 798-802 (1999).
-
(1999)
Nature
, vol.399
, pp. 798-802
-
-
Ishitani, T.1
-
41
-
-
0033600227
-
MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans
-
Meneghini, M. D. et al. MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans. Nature 399, 793-797 (1999).
-
(1999)
Nature
, vol.399
, pp. 793-797
-
-
Meneghini, M.D.1
-
42
-
-
0035869002
-
Naked cuticle targets Dishevelled to antagonize Wnt signal transduction
-
Rousset, R. et al. Naked cuticle targets Dishevelled to antagonize Wnt signal transduction. Genes Dev. 15, 658-671 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 658-671
-
-
Rousset, R.1
-
43
-
-
0035957382
-
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
-
Yan, D. et al. Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd. Proc. Natl Acad. Sci. USA 98, 3802-3807 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 3802-3807
-
-
Yan, D.1
-
44
-
-
74749106487
-
RORα attenuates Wnt/β-catenin signaling by PKCα-dependent phosphorylation in colon cancer
-
Lee, J. M. et al. RORα attenuates Wnt/β-catenin signaling by PKCα-dependent phosphorylation in colon cancer. Mol. Cell 37, 183-195 (2010).
-
(2010)
Mol. Cell
, vol.37
, pp. 183-195
-
-
Lee, J.M.1
-
45
-
-
73949156925
-
Ror-family receptor tyrosine kinases in noncanonical Wnt signaling: Their implications in developmental morphogenesis and human diseases
-
Minami, Y., Oishi, I., Endo, M. & Nishita, M. Ror-family receptor tyrosine kinases in noncanonical Wnt signaling: their implications in developmental morphogenesis and human diseases. Dev. Dyn. 239, 1-15 (2010).
-
(2010)
Dev. Dyn.
, vol.239
, pp. 1-15
-
-
Minami, Y.1
Oishi, I.2
Endo, M.3
Nishita, M.4
-
46
-
-
75649084593
-
Wnt5a regulates distinct signalling pathways by binding to Frizzled2
-
Sato, A., Yamamoto, H., Sakane, H., Koyama, H. & Kikuchi, A. Wnt5a regulates distinct signalling pathways by binding to Frizzled2. EMBO J. 29, 41-54 (2010).
-
(2010)
EMBO J.
, vol.29
, pp. 41-54
-
-
Sato, A.1
Yamamoto, H.2
Sakane, H.3
Koyama, H.4
Kikuchi, A.5
-
47
-
-
77950526433
-
Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells
-
Matsumoto, S., Fumoto, K., Okamoto, T., Kaibuchi, K. & Kikuchi, A. Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells. EMBO J. 29, 1192-1204 (2010).
-
(2010)
EMBO J.
, vol.29
, pp. 1192-1204
-
-
Matsumoto, S.1
Fumoto, K.2
Okamoto, T.3
Kaibuchi, K.4
Kikuchi, A.5
-
48
-
-
44649182871
-
Original CIN: Reviewing roles for APC in chromosome instability
-
Rusan, N. M. & Peifer, M. Original CIN: reviewing roles for APC in chromosome instability. J. Cell Biol. 181, 719-726 (2008).
-
(2008)
J. Cell Biol.
, vol.181
, pp. 719-726
-
-
Rusan, N.M.1
Peifer, M.2
-
49
-
-
73849123750
-
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma
-
O'Connell, M. P. et al. The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. Oncogene 29, 34-44 (2010).
-
(2010)
Oncogene
, vol.29
, pp. 34-44
-
-
O'Connell, M.P.1
-
50
-
-
36448970568
-
WNT5A, a putative tumour suppressor of lymphoid malignancies, is inactivated by aberrant methylation in acute lymphoblastic leukaemia
-
Roman-Gomez, J. et al. WNT5A, a putative tumour suppressor of lymphoid malignancies, is inactivated by aberrant methylation in acute lymphoblastic leukaemia. Eur. J. Cancer 43, 2736-2746 (2007).
-
(2007)
Eur. J. Cancer
, vol.43
, pp. 2736-2746
-
-
Roman-Gomez, J.1
-
51
-
-
10744219743
-
The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway
-
Oishi, I. et al. The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway. Genes Cells 8, 645-654 (2003).
-
(2003)
Genes Cells
, vol.8
, pp. 645-654
-
-
Oishi, I.1
-
52
-
-
33646241997
-
Purified Wnt5a protein activates or inhibits β-catenin-TCF signaling depending on receptor context
-
Mikels, A. J. & Nusse, R. Purified Wnt5a protein activates or inhibits β-catenin-TCF signaling depending on receptor context. PLoS Biol. 4, e115 (2006).
-
(2006)
PLoS Biol.
, vol.4
-
-
Mikels, A.J.1
Nusse, R.2
-
53
-
-
0030941498
-
A member of the Frizzled protein family mediating axis induction by Wnt-5A
-
He, X. et al. A member of the Frizzled protein family mediating axis induction by Wnt-5A. Science 275, 1652-1654 (1997).
-
(1997)
Science
, vol.275
, pp. 1652-1654
-
-
He, X.1
-
54
-
-
54249099446
-
Ror receptor tyrosine kinases: Orphans no more
-
Green, J. L., Kuntz, S. G. & Sternberg, P. W. Ror receptor tyrosine kinases: orphans no more. Trends Cell Biol. 18, 536-544 (2008).
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 536-544
-
-
Green, J.L.1
Kuntz, S.G.2
Sternberg, P.W.3
-
55
-
-
46049083566
-
Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex
-
Yamamoto, S. et al. Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. Dev. Cell 15, 23-36 (2008).
-
(2008)
Dev. Cell
, vol.15
, pp. 23-36
-
-
Yamamoto, S.1
-
56
-
-
2642583350
-
Wnt signaling: Ig-norrin the dogma
-
Clevers, H. Wnt signaling: Ig-norrin the dogma. Curr. Biol. 14, R436-R437 (2004).
-
(2004)
Curr. Biol.
, vol.14
-
-
Clevers, H.1
-
57
-
-
61749089153
-
The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie
-
Badouel, C. et al. The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie. Dev. Cell 16, 411-420 (2009).
-
(2009)
Dev. Cell
, vol.16
, pp. 411-420
-
-
Badouel, C.1
-
58
-
-
40849086201
-
Scalloped interacts with Yorkie, the nuclear effector of the Hippo tumor-suppressor pathway in Drosophila
-
Goulev, Y. et al. Scalloped interacts with Yorkie, the nuclear effector of the Hippo tumor-suppressor pathway in Drosophila. Curr. Biol. 18, 435-441 (2008).
-
(2008)
Curr. Biol.
, vol.18
, pp. 435-441
-
-
Goulev, Y.1
-
59
-
-
42049116586
-
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway
-
Wu, S., Liu, Y., Zheng, Y., Dong, J. & Pan, D. The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev. Cell 14, 388-398 (2008).
-
(2008)
Dev. Cell
, vol.14
, pp. 388-398
-
-
Wu, S.1
Liu, Y.2
Zheng, Y.3
Dong, J.4
Pan, D.5
-
60
-
-
42049120338
-
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control
-
Zhang, L. et al. The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. Dev. Cell 14, 377-387 (2008).
-
(2008)
Dev. Cell
, vol.14
, pp. 377-387
-
-
Zhang, L.1
-
61
-
-
33750611115
-
Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway
-
Bennett, F. C. & Harvey, K. F. Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway. Curr. Biol. 16, 2101-2110 (2006).
-
(2006)
Curr. Biol.
, vol.16
, pp. 2101-2110
-
-
Bennett, F.C.1
Harvey, K.F.2
-
62
-
-
33749125438
-
Delineation of a Fat tumor suppressor pathway
-
Cho, E. et al. Delineation of a Fat tumor suppressor pathway. Nature Genet. 38, 1142-1150 (2006).
-
(2006)
Nature Genet.
, vol.38
, pp. 1142-1150
-
-
Cho, E.1
-
63
-
-
33750624298
-
The tumor-suppressor gene fat controls tissue growth upstream of Expanded in the Hippo signaling pathway
-
Silva, E., Tsatskis, Y., Gardano, L., Tapon, N. & McNeill, H. The tumor-suppressor gene fat controls tissue growth upstream of Expanded in the Hippo signaling pathway. Curr. Biol. 16, 2081-2089 (2006).
-
(2006)
Curr. Biol.
, vol.16
, pp. 2081-2089
-
-
Silva, E.1
Tsatskis, Y.2
Gardano, L.3
Tapon, N.4
McNeill, H.5
-
64
-
-
33750614445
-
The Fat cadherin acts through the Hippo tumor-suppressor pathway to regulate tissue size
-
Willecke, M. et al. The Fat cadherin acts through the Hippo tumor-suppressor pathway to regulate tissue size. Curr. Biol. 16, 2090-2100 (2006).
-
(2006)
Curr. Biol.
, vol.16
, pp. 2090-2100
-
-
Willecke, M.1
-
65
-
-
46149099112
-
The Hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarity
-
Yu, J., Poulton, J., Huang, Y. C. & Deng, W. M. The Hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarity. PLoS One 3, e1761 (2008).
-
(2008)
PLoS One
, vol.3
-
-
Yu, J.1
Poulton, J.2
Huang, Y.C.3
Deng, W.M.4
-
66
-
-
35548970323
-
The Salvador-Warts-Hippo pathway is required for epithelial proliferation and axis specification in Drosophila
-
Meignin, C., Alvarez-Garcia, I., Davis, I. & Palacios, I. M. The Salvador-Warts-Hippo pathway is required for epithelial proliferation and axis specification in Drosophila. Curr. Biol. 17, 1871-1878 (2007).
-
(2007)
Curr. Biol.
, vol.17
, pp. 1871-1878
-
-
Meignin, C.1
Alvarez-Garcia, I.2
Davis, I.3
Palacios, I.M.4
-
67
-
-
35548957838
-
Salvador-Warts-Hippo signaling promotes Drosophila posterior follicle cell maturation downstream of Notch
-
Polesello, C. & Tapon, N. Salvador-Warts-Hippo signaling promotes Drosophila posterior follicle cell maturation downstream of Notch. Curr. Biol. 17, 1864-1870 (2007).
-
(2007)
Curr. Biol.
, vol.17
, pp. 1864-1870
-
-
Polesello, C.1
Tapon, N.2
-
68
-
-
30344445706
-
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
-
Hamaratoglu, F. et al. The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nature Cell Biol. 8, 27-36 (2006).
-
(2006)
Nature Cell Biol.
, vol.8
, pp. 27-36
-
-
Hamaratoglu, F.1
-
69
-
-
67649842389
-
Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase Discs overgrown
-
Sopko, R. et al. Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase Discs overgrown. Curr. Biol. 19, 1112-1117 (2009).
-
(2009)
Curr. Biol.
, vol.19
, pp. 1112-1117
-
-
Sopko, R.1
-
70
-
-
67749093511
-
Processing and phosphorylation of the Fat receptor
-
Feng, Y. & Irvine, K. D. Processing and phosphorylation of the Fat receptor. Proc. Natl Acad. Sci. USA 106, 11989-11994 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 11989-11994
-
-
Feng, Y.1
Irvine, K.D.2
-
71
-
-
76249109900
-
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
-
Yu, J. et al. Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev. Cell 18, 288-299 (2010).
-
(2010)
Dev. Cell
, vol.18
, pp. 288-299
-
-
Yu, J.1
-
72
-
-
76249125346
-
The WW domain protein Kibra acts upstream of Hippo in Drosophila
-
Baumgartner, R., Poernbacher, I., Buser, N., Hafen, E. & Stocker, H. The WW domain protein Kibra acts upstream of Hippo in Drosophila. Dev. Cell 18, 309-316 (2010).
-
(2010)
Dev. Cell
, vol.18
, pp. 309-316
-
-
Baumgartner, R.1
Poernbacher, I.2
Buser, N.3
Hafen, E.4
Stocker, H.5
-
73
-
-
76249093838
-
Kibra is a regulator of the Salvador/Warts/Hippo signaling network
-
Genevet, A., Wehr, M. C., Brain, R., Thompson, B. J. & Tapon, N. Kibra is a regulator of the Salvador/Warts/Hippo signaling network. Dev. Cell 18, 300-308 (2010).
-
(2010)
Dev. Cell
, vol.18
, pp. 300-308
-
-
Genevet, A.1
Wehr, M.C.2
Brain, R.3
Thompson, B.J.4
Tapon, N.5
-
74
-
-
70349786516
-
Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling
-
Oh, H., Reddy, B. V. & Irvine, K. D. Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling. Dev. Biol. 335, 188-197 (2009).
-
(2009)
Dev. Biol.
, vol.335
, pp. 188-197
-
-
Oh, H.1
Reddy, B.V.2
Irvine, K.D.3
-
75
-
-
48749101754
-
Morphogen control of wing growth through the Fat signaling pathway
-
Rogulja, D., Rauskolb, C. & Irvine, K. D. Morphogen control of wing growth through the Fat signaling pathway. Dev. Cell 15, 309-321 (2008).
-
(2008)
Dev. Cell
, vol.15
, pp. 309-321
-
-
Rogulja, D.1
Rauskolb, C.2
Irvine, K.D.3
-
76
-
-
47749136645
-
The tumor suppressor genes dachsous and fat modulate different signalling pathways by regulating Dally and Dally-like
-
Baena-Lopez, L. A., Rodriguez, I. & Baonza, A. The tumor suppressor genes dachsous and fat modulate different signalling pathways by regulating Dally and Dally-like. Proc. Natl Acad. Sci. USA 105, 9645-9650 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 9645-9650
-
-
Baena-Lopez, L.A.1
Rodriguez, I.2
Baonza, A.3
-
77
-
-
55849112207
-
Signalling molecules, growth regulators and cell cycle control in Drosophila
-
Herranz, H. & Milan, M. Signalling molecules, growth regulators and cell cycle control in Drosophila. Cell Cycle 7, 3335-3337 (2008).
-
(2008)
Cell Cycle
, vol.7
, pp. 3335-3337
-
-
Herranz, H.1
Milan, M.2
-
78
-
-
70349624119
-
Transcription factor choice in the Hippo signaling pathway: Homothorax and Yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc
-
Peng, H. W., Slattery, M. & Mann, R. S. Transcription factor choice in the Hippo signaling pathway: Homothorax and Yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc. Genes Dev. 23, 2307-2319 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 2307-2319
-
-
Peng, H.W.1
Slattery, M.2
Mann, R.S.3
-
79
-
-
70350780570
-
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-β pathways
-
Alarcon, C. et al. Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-β pathways. Cell 139, 757-769 (2009).
-
(2009)
Cell
, vol.139
, pp. 757-769
-
-
Alarcon, C.1
-
80
-
-
72549090299
-
YAP1 is amplified and up-regulated in Hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
-
Fernandez, L. A. et al. YAP1 is amplified and up-regulated in Hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. Genes Dev. 23, 2729-2741 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 2729-2741
-
-
Fernandez, L.A.1
-
81
-
-
77951915105
-
The Hippo pathway regulates Wnt/β-catenin signalling
-
Varelas, X. et al. The Hippo pathway regulates Wnt/β-catenin signalling. Dev. Cell 18, 579-591 (2010).
-
(2010)
Dev. Cell
, vol.18
, pp. 579-591
-
-
Varelas, X.1
-
82
-
-
77950470207
-
Phosphoinositide 3-kinase/Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120
-
Yuan, Z. et al. Phosphoinositide 3-kinase/Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120. J. Biol. Chem. 285, 3815-3824 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 3815-3824
-
-
Yuan, Z.1
-
83
-
-
73349128777
-
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway
-
Zhang, J. et al. YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nature Cell Biol. 11, 1444-1450 (2009).
-
(2009)
Nature Cell Biol.
, vol.11
, pp. 1444-1450
-
-
Zhang, J.1
-
84
-
-
70350502865
-
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
-
Zhou, D. et al. Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell 16, 425-438 (2009).
-
(2009)
Cancer Cell
, vol.16
, pp. 425-438
-
-
Zhou, D.1
-
85
-
-
34248595035
-
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases
-
Owens, D. M. & Keyse, S. M. Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases. Oncogene 26, 3203-3213 (2007).
-
(2007)
Oncogene
, vol.26
, pp. 3203-3213
-
-
Owens, D.M.1
Keyse, S.M.2
-
86
-
-
70349695861
-
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
-
Huang, S. M. et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 461, 614-620 (2009).
-
(2009)
Nature
, vol.461
, pp. 614-620
-
-
Huang, S.M.1
-
87
-
-
41549132691
-
Quantitative analysis of pathways controlling extrinsic apoptosis in single cells
-
Albeck, J. G. et al. Quantitative analysis of pathways controlling extrinsic apoptosis in single cells. Mol. Cell 30, 11-25 (2008).
-
(2008)
Mol. Cell
, vol.30
, pp. 11-25
-
-
Albeck, J.G.1
-
88
-
-
62049085035
-
The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc
-
Arnold, H. K. et al. The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc. EMBO J. 28, 500-512 (2009).
-
(2009)
EMBO J.
, vol.28
, pp. 500-512
-
-
Arnold, H.K.1
-
89
-
-
71149092489
-
Evidence that fold-change, and not absolute level, of β-catenin dictates Wnt signaling
-
Goentoro, L. & Kirschner, M. W. Evidence that fold-change, and not absolute level, of β-catenin dictates Wnt signaling. Mol. Cell 36, 872-884 (2009).
-
(2009)
Mol. Cell
, vol.36
, pp. 872-884
-
-
Goentoro, L.1
Kirschner, M.W.2
-
90
-
-
76749147440
-
Genetic dissection of differential signaling threshold requirements for the Wnt/β-catenin pathway in vivo
-
Buchert, M. et al. Genetic dissection of differential signaling threshold requirements for the Wnt/β-catenin pathway in vivo. PLoS Genet. 6, e1000816 (2010).
-
(2010)
PLoS Genet.
, vol.6
-
-
Buchert, M.1
-
91
-
-
58149239950
-
The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex
-
Yokota, Y. et al. The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex. Neuron 61, 42-56 (2009).
-
(2009)
Neuron
, vol.61
, pp. 42-56
-
-
Yokota, Y.1
-
92
-
-
71149099313
-
The incoherent feedforward loop can provide fold-change detection in gene regulation
-
Goentoro, L., Shoval, O., Kirschner, M. W. & Alon, U. The incoherent feedforward loop can provide fold-change detection in gene regulation. Mol. Cell 36, 894-899 (2009).
-
(2009)
Mol. Cell
, vol.36
, pp. 894-899
-
-
Goentoro, L.1
Shoval, O.2
Kirschner, M.W.3
Alon, U.4
-
93
-
-
80051806451
-
GSK-3 is a master regulator of neural progenitor homeostasis
-
Kim, W. Y. et al. GSK-3 is a master regulator of neural progenitor homeostasis. Nature Neurosci. 12, 1390-1397 (2009).
-
(2009)
Nature Neurosci.
, vol.12
, pp. 1390-1397
-
-
Kim, W.Y.1
|