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Volumn 28, Issue 35, 2009, Pages 3121-3131

Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines

Author keywords

Akt; CGMP dependent protein kinase II; Glioma; PDGF; Sox9; VASP

Indexed keywords

8 (4 CHLOROPHENYLTHIO) CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE 2; PROTEIN KINASE B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; VASODILATOR STIMULATED PHOSPHOPROTEIN;

EID: 69849089410     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.168     Document Type: Article
Times cited : (80)

References (43)
  • 1
    • 0028303913 scopus 로고
    • CAMP-and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets
    • Butt E, Abel K, Krieger M, Palm D, Hoppe V, Hoppe J et al. (1994). cAMP-and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets. J Biol Chem 269: 14509-14517.
    • (1994) J Biol Chem , vol.269 , pp. 14509-14517
    • Butt, E.1    Abel, K.2    Krieger, M.3    Palm, D.4    Hoppe, V.5    Hoppe, J.6
  • 2
    • 48549098685 scopus 로고    scopus 로고
    • Activation of protein kinase G increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1
    • Cen B, Deguchi A, Weinstein IB. (2008). Activation of protein kinase G increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1. Cancer Res 68: 5355-5362.
    • (2008) Cancer Res , vol.68 , pp. 5355-5362
    • Cen, B.1    Deguchi, A.2    Weinstein, I.B.3
  • 3
    • 3943087022 scopus 로고    scopus 로고
    • Vasodilator-stimulated phosphoprotein regulates proliferation and growth inhibition by nitric oxide in vascular smooth muscle cells
    • Chen L, Daum G, Chitaley K, Coats SA, Bowen-Pope DF, Eigenthaler M et al. (2004). Vasodilator-stimulated phosphoprotein regulates proliferation and growth inhibition by nitric oxide in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 24: 1403-1408.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1403-1408
    • Chen, L.1    Daum, G.2    Chitaley, K.3    Coats, S.A.4    Bowen-Pope, D.F.5    Al Et, E.M.6
  • 4
    • 0346121540 scopus 로고    scopus 로고
    • Neural crest development is regulated by the transcription factor Sox9
    • Cheung M, Briscoe J. (2003). Neural crest development is regulated by the transcription factor Sox9. Development 130: 5681-5693.
    • (2003) Development , vol.130 , pp. 5681-5693
    • Cheung, M.1    Briscoe, J.2
  • 5
    • 4644287296 scopus 로고    scopus 로고
    • Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes
    • Chikuda H, Kugimiya F, Hoshi K, Ikeda T, Ogasawara T, Shimoaka T et al. (2004). Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes. Genes Dev 18: 2418-2429.
    • (2004) Genes Dev , vol.18 , pp. 2418-2429
    • Chikuda, H.1    Kugimiya, F.2    Hoshi, K.3    Ikeda, T.4    Ogasawara, T.5    Shimoaka, T.6
  • 6
    • 0344014113 scopus 로고    scopus 로고
    • Protein kinase G II-mediated proliferative effects in human cultured prostatic stromal cells
    • Cook AL, Haynes JM. (2004). Protein kinase G II-mediated proliferative effects in human cultured prostatic stromal cells. Cell Signal 16: 253-261.
    • (2004) Cell Signal , vol.16 , pp. 253-261
    • Cook, A.L.1    Haynes, J.M.2
  • 7
    • 2542619027 scopus 로고    scopus 로고
    • Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells
    • Deguchi A, Thompson WJ, Weinstein IB. (2004). Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells. Cancer Res 64: 3966-3973.
    • (2004) Cancer Res , vol.64 , pp. 3966-3973
    • Deguchi, A.1    Thompson, W.J.2    Weinstein, I.B.3
  • 8
    • 33846904534 scopus 로고    scopus 로고
    • NG2 and Olig2 expression provides evidence for phenotypic deregulation of cultured central nervous system and peripheral nervous system neural precursor cells
    • Dromard C, Bartolami S, Deleyrolle L, Takebayashi H, Ripoll C, Simonneau L et al. (2007). NG2 and Olig2 expression provides evidence for phenotypic deregulation of cultured central nervous system and peripheral nervous system neural precursor cells. Stem Cells 25: 340-353.
    • (2007) Stem Cells , vol.25 , pp. 340-353
    • Dromard, C.1    Bartolami, S.2    Deleyrolle, L.3    Takebayashi, H.4    Ripoll, C.5    Simonneau, L.6
  • 9
    • 40949084666 scopus 로고    scopus 로고
    • Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression
    • Finzsch M, Stolt CC, Lommes P, Wegner M. (2008). Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression. Development 135: 637-646.
    • (2008) Development , vol.135 , pp. 637-646
    • Finzsch, M.1    Stolt, C.C.2    Lommes, P.3    Wegner, M.4
  • 11
    • 0032764586 scopus 로고    scopus 로고
    • Nitric oxide and cGMP regulate gene expression in neuronal and glial cells by activating type II cGMP-dependent protein kinase
    • Gudi T, Hong GK, Vaandrager AB, Lohmann SM, Pilz RB. (1999). Nitric oxide and cGMP regulate gene expression in neuronal and glial cells by activating type II cGMP-dependent protein kinase. FASEB J 13: 2143-2152.
    • (1999) FASEB J , vol.13 , pp. 2143-2152
    • Gudi, T.1    Hong, G.K.2    Vaandrager, A.B.3    Lohmann, S.M.4    Pilz, R.B.5
  • 12
    • 0028911678 scopus 로고
    • Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop
    • Guha A, Dashner K, Black PM, Wagner JA, Stiles CD. (1995). Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop. Int J Cancer 60: 168-173.
    • (1995) Int J Cancer , vol.60 , pp. 168-173
    • Guha, A.1    Dashner, K.2    Black, P.M.3    Wagner, J.A.4    Stiles, C.D.5
  • 14
    • 33644834949 scopus 로고    scopus 로고
    • Function of cGMP-dependent protein kinases as revealed by gene deletion
    • Hofmann F, Feil R, Kleppisch T, Schlossmann J. (2006). Function of cGMP-dependent protein kinases as revealed by gene deletion. Physiol Rev 86: 1-23.
    • (2006) Physiol Rev , vol.86 , pp. 1-23
    • Hofmann, F.1    Feil, R.2    Kleppisch, T.3    Schlossmann, J.4
  • 15
    • 0034020459 scopus 로고    scopus 로고
    • Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
    • Holland EC, Celestino J, Dai C, Schaefer L, Sawaya RE, Fuller GN. (2000). Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat Genet 25: 55-57.
    • (2000) Nat Genet , vol.25 , pp. 55-57
    • Holland, E.C.1    Celestino, J.2    Dai, C.3    Schaefer, L.4    Sawaya, R.E.5    Fuller, G.N.6
  • 17
    • 0023948602 scopus 로고
    • Amplification and expression of the epidermal growth factor receptor gene in human glioma xenografts
    • Humphrey PA, Wong AJ, Vogelstein B, Friedman HS, Werner MH, Bigner DD et al. (1988). Amplification and expression of the epidermal growth factor receptor gene in human glioma xenografts. Cancer Res 48: 2231-2238.
    • (1988) Cancer Res , vol.48 , pp. 2231-2238
    • Humphrey, P.A.1    Wong, A.J.2    Vogelstein, B.3    Friedman, H.S.4    Werner, M.H.5    Bigner, D.D.6
  • 19
    • 20544449915 scopus 로고    scopus 로고
    • Expression analysis of genes involved in brain tumor progression driven by retroviral insertional mutagenesis in mice
    • Johansson FK, Goransson H, Westermark B. (2005). Expression analysis of genes involved in brain tumor progression driven by retroviral insertional mutagenesis in mice. Oncogene 24: 3896-3905.
    • (2005) Oncogene , vol.24 , pp. 3896-3905
    • Johansson, F.K.1    Goransson, H.2    Westermark, B.3
  • 20
    • 48949096144 scopus 로고    scopus 로고
    • Identifying candidate genes involved in brain tumor formation
    • Johansson Swartling F. (2008). Identifying candidate genes involved in brain tumor formation. Ups J Med Sci 113: 1-38.
    • (2008) Ups J Med Sci , vol.113 , pp. 1-38
    • Johansson Swartling, F.1
  • 21
    • 33750308573 scopus 로고    scopus 로고
    • Expression of SOX9 and SOX10 in central neuroepithelial tumor
    • Kordes U, Hagel C. (2006). Expression of SOX9 and SOX10 in central neuroepithelial tumor. J Neurooncol 80: 151-155.
    • (2006) J Neurooncol , vol.80 , pp. 151-155
    • Kordes, U.1    Hagel, C.2
  • 22
    • 38549089581 scopus 로고    scopus 로고
    • Activity of imatinib in systemic mastocytosis with chronic basophilic leukemia and a PRKG2-PDGFRB fusion
    • Lahortiga I, Akin C, Cools J, Wilson TM, Mentens N, Arthur DC et al. (2008). Activity of imatinib in systemic mastocytosis with chronic basophilic leukemia and a PRKG2-PDGFRB fusion. Haematologica 93: 49-56.
    • (2008) Haematologica , vol.93 , pp. 49-56
    • Lahortiga, I.1    Akin, C.2    Cools, J.3    Wilson, T.M.4    Mentens, N.5    Arthur, D.C.6
  • 23
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI et al. (1997). PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275: 1943-1947.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3    Podsypanina, K.4    Bose, S.5    Wang, S.I.6
  • 24
    • 0021932240 scopus 로고
    • Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
    • Libermann TA, Nusbaum HR, Razon N, Kris R, Lax I, Soreq H et al. (1985). Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature 313: 144-147.
    • (1985) Nature , vol.313 , pp. 144-147
    • Libermann, T.A.1    Nusbaum, H.R.2    Razon, N.3    Kris, R.4    Lax, I.5    Soreq, H.6
  • 25
    • 0023747564 scopus 로고
    • Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines
    • Nister M, Libermann TA, Betsholtz C, Pettersson M, Claesson-Welsh L, Heldin CH et al. (1988). Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines. Cancer Res 48: 3910-3918.
    • (1988) Cancer Res , vol.48 , pp. 3910-3918
    • Nister, M.1    Libermann, T.A.2    Betsholtz, C.3    Pettersson, M.4    Claesson-Welsh, L.5    Heldin, C.H.6
  • 27
    • 33644820339 scopus 로고    scopus 로고
    • Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
    • Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD et al. (2006). Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9: 157-173.
    • (2006) Cancer Cell , vol.9 , pp. 157-173
    • Phillips, H.S.1    Kharbanda, S.2    Chen, R.3    Forrest, W.F.4    Soriano, R.H.5    Wu, T.D.6
  • 29
    • 0034682801 scopus 로고    scopus 로고
    • Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I
    • DOI 10.1074/jbc.M909632199
    • Smolenski A, Poller W, Walter U, Lohmann SM. (2000). Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I. J Biol Chem 275: 25723-25732. (Pubitemid 30687076)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.33 , pp. 25723-25732
    • Smolenski, A.1    Poller, W.2    Walter, U.3    Lohmann, S.M.4
  • 30
    • 33746090935 scopus 로고    scopus 로고
    • Stem cell marker expression in the Bergmann glia population of the adult mouse brain
    • Sottile V, Li M, Scotting PJ. (2006). Stem cell marker expression in the Bergmann glia population of the adult mouse brain. Brain Res 1099: 8-17.
    • (2006) Brain Res , vol.1099 , pp. 8-17
    • Sottile, V.1    Li, M.2    Scotting, P.J.3
  • 31
    • 17144436629 scopus 로고    scopus 로고
    • Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23. 3 that is mutated in multiple advanced cancers
    • Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, Ligon AH et al. (1997). Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23. 3 that is mutated in multiple advanced cancers. Nat Genet 15: 356-362.
    • (1997) Nat Genet , vol.15 , pp. 356-362
    • Steck, P.A.1    Pershouse, M.A.2    Jasser, S.A.3    Yung, W.K.4    Lin, H.5    Ligon, A.H.6
  • 32
    • 0037663384 scopus 로고    scopus 로고
    • The Sox9 transcription factor determines glial fate choice in the developing spinal cord
    • Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M. (2003). The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev 17: 1677-1689.
    • (2003) Genes Dev , vol.17 , pp. 1677-1689
    • Stolt, C.C.1    Lommes, P.2    Sock, E.3    Chaboissier, M.C.4    Schedl, A.5    Wegner, M.6
  • 33
    • 0031128036 scopus 로고    scopus 로고
    • Nitric oxide-mediated cGMP synthesis in oligodendrocytes in the developing rat brain
    • Tanaka J, Markerink-van Ittersum M, Steinbusch HW, De Vente J. (1997). Nitric oxide-mediated cGMP synthesis in oligodendrocytes in the developing rat brain. Glia 19: 286-297.
    • (1997) Glia , vol.19 , pp. 286-297
    • Tanaka, J.1    Markerink-Van Ittersum, M.2    Steinbusch, H.W.3    De Vente, J.4
  • 34
    • 0037020236 scopus 로고    scopus 로고
    • Autoinhibition and isoform-specific dominant negative inhibition of the type II cGMP-dependent protein kinase
    • Taylor MK, Ahmed R, Begley M, Uhler MD. (2002). Autoinhibition and isoform-specific dominant negative inhibition of the type II cGMP-dependent protein kinase. J Biol Chem 277: 37242-37253.
    • (2002) J Biol Chem , vol.277 , pp. 37242-37253
    • Taylor, M.K.1    Ahmed, R.2    Begley, M.3    Uhler, M.D.4
  • 35
    • 0032401819 scopus 로고    scopus 로고
    • Induction of brain tumors in mice using a recombinant platelet-derived growth factor B-chain retrovirus
    • Uhrbom L, Hesselager G, Nister M, Westermark B. (1998). Induction of brain tumors in mice using a recombinant platelet-derived growth factor B-chain retrovirus. Cancer Res 58: 5275-5279.
    • (1998) Cancer Res , vol.58 , pp. 5275-5279
    • Uhrbom, L.1    Hesselager, G.2    Nister, M.3    Westermark, B.4
  • 36
    • 33646697351 scopus 로고    scopus 로고
    • Nitric oxide and cell proliferation
    • Villalobo A. (2006). Nitric oxide and cell proliferation. FEBS J 273: 2329-2344.
    • (2006) FEBS J , vol.273 , pp. 2329-2344
    • Villalobo, A.1
  • 37
    • 0020530724 scopus 로고
    • A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis
    • Vindelov LL, Christensen IJ, Nissen NI. (1983). A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 3: 323-327.
    • (1983) Cytometry , vol.3 , pp. 323-327
    • Vindelov, L.L.1    Christensen, I.J.2    Nissen, N.I.3
  • 38
    • 33947543336 scopus 로고    scopus 로고
    • Characterization of three new imatinib-responsive fusion genes in chronic myeloproliferative disorders generated by disruption of the platelet-derived growth factor receptor beta gene
    • Walz C, Metzgeroth G, Haferlach C, Schmitt-Graeff A, Fabarius A, Hagen V et al. (2007). Characterization of three new imatinib-responsive fusion genes in chronic myeloproliferative disorders generated by disruption of the platelet-derived growth factor receptor beta gene. Haematologica 92: 163-169.
    • (2007) Haematologica , vol.92 , pp. 163-169
    • Walz, C.1    Metzgeroth, G.2    Haferlach, C.3    Schmitt-Graeff, A.4    Fabarius, A.5    Hagen, V.6
  • 39
    • 40949145618 scopus 로고    scopus 로고
    • SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion
    • Wang H, Leav I, Ibaragi S, Wegner M, Hu GF, Lu ML et al. (2008). SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion. Cancer Res 68: 1625-1630.
    • (2008) Cancer Res , vol.68 , pp. 1625-1630
    • Wang, H.1    Leav, I.2    Ibaragi, S.3    Wegner, M.4    Hu, G.F.5    Lu, M.L.6
  • 40
    • 33846673020 scopus 로고    scopus 로고
    • SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells
    • Wang H, McKnight NC, Zhang T, Lu ML, Balk SP, Yuan X. (2007). SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells. Cancer Res 67: 528-536.
    • (2007) Cancer Res , vol.67 , pp. 528-536
    • Wang, H.1    McKnight, N.C.2    Zhang, T.3    Lu, M.L.4    Balk, S.P.5    Yuan, X.6
  • 42
    • 52449089214 scopus 로고    scopus 로고
    • Increase in brain tumor permeability in glioma-bearing rats with nitric oxide donors
    • Yin D, Wang X, Konda BM, Ong JM, Hu J, Sacapano MR et al. (2008). Increase in brain tumor permeability in glioma-bearing rats with nitric oxide donors. Clin Cancer Res 14: 4002-4009.
    • (2008) Clin Cancer Res , vol.14 , pp. 4002-4009
    • Yin, D.1    Wang, X.2    Konda, B.M.3    Ong, J.M.4    Hu, J.5    Sacapano, M.R.6
  • 43
    • 0033979856 scopus 로고    scopus 로고
    • Cyclic GMP/cyclic GMP-dependent protein kinase system prevents excitotoxicity in an immortalized oligodendroglial cell line
    • Yoshioka A, Yamaya Y, Saiki S, Kanemoto M, Hirose G, Pleasure D. (2000). Cyclic GMP/cyclic GMP-dependent protein kinase system prevents excitotoxicity in an immortalized oligodendroglial cell line. J Neurochem 74: 633-640.
    • (2000) J Neurochem , vol.74 , pp. 633-640
    • Yoshioka, A.1    Yamaya, Y.2    Saiki, S.3    Kanemoto, M.4    Hirose, G.5    Pleasure, D.6


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