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Volumn 1, Issue 1, 2011, Pages

Lithium promotes neural precursor cell proliferation: Evidence for the involvement of the non-canonical GSK-3β-NF-AT signaling

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EID: 80052903796     PISSN: None     EISSN: 20453701     Source Type: Journal    
DOI: 10.1186/2045-3701-1-18     Document Type: Article
Times cited : (26)

References (43)
  • 1
    • 28844475505 scopus 로고    scopus 로고
    • The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials
    • 10.1196/annals.1344.018, 16179524
    • Chuang DM. The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials. Ann N Y Acad Sci 2005, 1053:195-204. 10.1196/annals.1344.018, 16179524.
    • (2005) Ann N Y Acad Sci , vol.1053 , pp. 195-204
    • Chuang, D.M.1
  • 2
    • 29144471908 scopus 로고    scopus 로고
    • Lithium: potential therapeutics against acute brain injuries and chronic neurodegenerative diseases
    • 10.1254/jphs.CRJ05009X, 16340157
    • Wada A, Yokoo H, Yanagita T, Kobayashi H. Lithium: potential therapeutics against acute brain injuries and chronic neurodegenerative diseases. J Pharmacol Sci 2005, 99:307-321. 10.1254/jphs.CRJ05009X, 16340157.
    • (2005) J Pharmacol Sci , vol.99 , pp. 307-321
    • Wada, A.1    Yokoo, H.2    Yanagita, T.3    Kobayashi, H.4
  • 3
    • 0024341795 scopus 로고
    • Neural and developmental actions of lithium: a unifying hypothesis
    • 10.1016/0092-8674(89)90026-3, 2553271
    • Berridge MJ, Downes CP, Hanley MR. Neural and developmental actions of lithium: a unifying hypothesis. Cell 1989, 59:411-419. 10.1016/0092-8674(89)90026-3, 2553271.
    • (1989) Cell , vol.59 , pp. 411-419
    • Berridge, M.J.1    Downes, C.P.2    Hanley, M.R.3
  • 4
    • 0032864255 scopus 로고    scopus 로고
    • Inhibition of the high affinity myo-inositol transport system: a common mechanism of action of antibipolar drugs?
    • 10.1016/S0893-133X(99)00037-8, 10481836
    • Lubrich B, van Calker D. Inhibition of the high affinity myo-inositol transport system: a common mechanism of action of antibipolar drugs?. Neuropsychopharmacology 1999, 21:519-529. 10.1016/S0893-133X(99)00037-8, 10481836.
    • (1999) Neuropsychopharmacology , vol.21 , pp. 519-529
    • Lubrich, B.1    van Calker, D.2
  • 5
    • 42949133776 scopus 로고    scopus 로고
    • Homozygote inositol transporter knockout mice show a lithium-like phenotype
    • 10.1111/j.1399-5618.2007.00546.x, 18452441
    • Bersudsky Y, Shaldubina A, Agam G, Berry GT, Belmaker RH. Homozygote inositol transporter knockout mice show a lithium-like phenotype. Bipolar Disord 2008, 10:453-459. 10.1111/j.1399-5618.2007.00546.x, 18452441.
    • (2008) Bipolar Disord , vol.10 , pp. 453-459
    • Bersudsky, Y.1    Shaldubina, A.2    Agam, G.3    Berry, G.T.4    Belmaker, R.H.5
  • 7
    • 20544437694 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs
    • Gould TD, Manji HK. Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs. Neuropsychopharmacology 2005, 30:1223-1237.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1223-1237
    • Gould, T.D.1    Manji, H.K.2
  • 8
    • 0030449964 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
    • 10.1016/S0960-9822(02)70790-2, 8994831
    • Stambolic V, Ruel L, Woodgett JR. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr Biol 1996, 6:1664-1668. 10.1016/S0960-9822(02)70790-2, 8994831.
    • (1996) Curr Biol , vol.6 , pp. 1664-1668
    • Stambolic, V.1    Ruel, L.2    Woodgett, J.R.3
  • 9
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • 10.1073/pnas.93.16.8455, 38692, 8710892
    • Klein PS, Melton DA. A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci USA 1996, 93:8455-8459. 10.1073/pnas.93.16.8455, 38692, 8710892.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 10
    • 3342955475 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β haploinsufficiency mimics the behavioral and molecular effects of lithium
    • 10.1523/JNEUROSCI.4753-03.2004, 15282284
    • O'Brien WT, Harper AD, Jove F, Woodgett JR, Maretto S, Piccolo S, Klein PS. Glycogen synthase kinase-3β haploinsufficiency mimics the behavioral and molecular effects of lithium. J Neurosci 2004, 24:6791-6798. 10.1523/JNEUROSCI.4753-03.2004, 15282284.
    • (2004) J Neurosci , vol.24 , pp. 6791-6798
    • O'Brien, W.T.1    Harper, A.D.2    Jove, F.3    Woodgett, J.R.4    Maretto, S.5    Piccolo, S.6    Klein, P.S.7
  • 12
    • 68049121855 scopus 로고    scopus 로고
    • Blocked inhibitory serine-phosphorylation of glycogen synthase kinase-3α/β impairs in vivo neural precursor cell proliferation
    • 10.1016/j.biopsych.2009.04.015, 2746934, 19520363
    • Eom TY, Jope RS. Blocked inhibitory serine-phosphorylation of glycogen synthase kinase-3α/β impairs in vivo neural precursor cell proliferation. Biol Psychiatry 2009, 66:494-502. 10.1016/j.biopsych.2009.04.015, 2746934, 19520363.
    • (2009) Biol Psychiatry , vol.66 , pp. 494-502
    • Eom, T.Y.1    Jope, R.S.2
  • 13
    • 33644903202 scopus 로고    scopus 로고
    • Influence of retinoic acid and lithium on proliferation and dopaminergic potential of human NT2 cells
    • 10.1002/jnr.20718, 16408307
    • Misiuta IE, Saporta S, Sanberg PR, Zigova T, Willing AE. Influence of retinoic acid and lithium on proliferation and dopaminergic potential of human NT2 cells. J Neurosci Res 2006, 83:668-679. 10.1002/jnr.20718, 16408307.
    • (2006) J Neurosci Res , vol.83 , pp. 668-679
    • Misiuta, I.E.1    Saporta, S.2    Sanberg, P.R.3    Zigova, T.4    Willing, A.E.5
  • 14
    • 58149470596 scopus 로고    scopus 로고
    • Glucocorticoids and lithium reciprocally regulate the proliferation of adult dentate gyrus-derived neural precursor cells through GSK-3β and β-catenin/TCF pathway
    • 10.1038/npp.2008.198, 19005466
    • Boku S, Nakagawa S, Masuda T, Nishikawa H, Kato A, Kitaichi Y, Inoue T, Koyama T. Glucocorticoids and lithium reciprocally regulate the proliferation of adult dentate gyrus-derived neural precursor cells through GSK-3β and β-catenin/TCF pathway. Neuropsychopharmacology 2009, 34:805-815. 10.1038/npp.2008.198, 19005466.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 805-815
    • Boku, S.1    Nakagawa, S.2    Masuda, T.3    Nishikawa, H.4    Kato, A.5    Kitaichi, Y.6    Inoue, T.7    Koyama, T.8
  • 15
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: tricks of the trade for a multi-tasking kinase
    • 10.1242/jcs.00384, 3006448, 12615961
    • Doble BW, Woodgett JR. GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci 2003, 116:1175-1186. 10.1242/jcs.00384, 3006448, 12615961.
    • (2003) J Cell Sci , vol.116 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 16
    • 0034600901 scopus 로고    scopus 로고
    • Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3
    • 10.1084/jem.192.1.99, 1887707, 10880530
    • Ohteki T, Parsons M, Zakarian A, Jones RG, Nguyen LT, Woodgett JR, Ohashi PS. Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3. J Exp Med 2000, 192:99-104. 10.1084/jem.192.1.99, 1887707, 10880530.
    • (2000) J Exp Med , vol.192 , pp. 99-104
    • Ohteki, T.1    Parsons, M.2    Zakarian, A.3    Jones, R.G.4    Nguyen, L.T.5    Woodgett, J.R.6    Ohashi, P.S.7
  • 17
  • 18
    • 0030890234 scopus 로고    scopus 로고
    • Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3
    • 10.1126/science.275.5308.1930, 9072970
    • Beals CR, Sheridan CM, Turck CW, Gardner P, Crabtree GR. Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3. Science 1997, 275:1930-1934. 10.1126/science.275.5308.1930, 9072970.
    • (1997) Science , vol.275 , pp. 1930-1934
    • Beals, C.R.1    Sheridan, C.M.2    Turck, C.W.3    Gardner, P.4    Crabtree, G.R.5
  • 19
    • 18144431373 scopus 로고    scopus 로고
    • Embryonic radial glia bridge spinal cord lesions and promote functional recovery following spinal cord injury
    • 10.1016/j.expneurol.2004.12.024, 15869942
    • Hasegawa K, Chang YW, Li H, Berlin Y, Ikeda O, Kane-Goldsmith N, Grumet M. Embryonic radial glia bridge spinal cord lesions and promote functional recovery following spinal cord injury. Exp Neurol 2005, 193:394-410. 10.1016/j.expneurol.2004.12.024, 15869942.
    • (2005) Exp Neurol , vol.193 , pp. 394-410
    • Hasegawa, K.1    Chang, Y.W.2    Li, H.3    Berlin, Y.4    Ikeda, O.5    Kane-Goldsmith, N.6    Grumet, M.7
  • 20
    • 0034718211 scopus 로고    scopus 로고
    • Effects of lithium and insulin on glycogen synthesis in L6 myocytes: additive effects on inactivation of glycogen synthase kinase-3
    • Choi WS, Sung CK. Effects of lithium and insulin on glycogen synthesis in L6 myocytes: additive effects on inactivation of glycogen synthase kinase-3. Biochim Biophys Acta 2000, 1475:225-230.
    • (2000) Biochim Biophys Acta , vol.1475 , pp. 225-230
    • Choi, W.S.1    Sung, C.K.2
  • 21
    • 0042971809 scopus 로고    scopus 로고
    • Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3
    • 10.1128/MCB.23.17.6027-6036.2003, 180950, 12917327
    • Hongisto V, Smeds N, Brecht S, Herdegen T, Courtney MJ, Coffey ET. Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3. Mol Cell Biol 2003, 23:6027-6036. 10.1128/MCB.23.17.6027-6036.2003, 180950, 12917327.
    • (2003) Mol Cell Biol , vol.23 , pp. 6027-6036
    • Hongisto, V.1    Smeds, N.2    Brecht, S.3    Herdegen, T.4    Courtney, M.J.5    Coffey, E.T.6
  • 22
    • 4744375264 scopus 로고    scopus 로고
    • GSK-3β inhibition by lithium confers resistance to chemotherapy-induced apoptosis through the repression of CD95 (Fas/APO-1) expression
    • 10.1016/j.yexcr.2004.08.001, 15475000
    • Beurel E, Kornprobst M, Blivet-Van Eggelpoel MJ, Ruiz-Ruiz C, Cadoret A, Capeau J, Desbois-Mouthon C. GSK-3β inhibition by lithium confers resistance to chemotherapy-induced apoptosis through the repression of CD95 (Fas/APO-1) expression. Exp Cell Res 2004, 300:354-364. 10.1016/j.yexcr.2004.08.001, 15475000.
    • (2004) Exp Cell Res , vol.300 , pp. 354-364
    • Beurel, E.1    Kornprobst, M.2    Blivet-Van Eggelpoel, M.J.3    Ruiz-Ruiz, C.4    Cadoret, A.5    Capeau, J.6    Desbois-Mouthon, C.7
  • 23
    • 20344363201 scopus 로고    scopus 로고
    • GSK-3 activity in neocortical cells is inhibited by lithium but not carbamazepine or valproic acid
    • 10.1111/j.1399-5618.2005.00194.x, 1249491, 15898963
    • Jonathan Ryves W, Dalton EC, Harwood AJ, Williams RS. GSK-3 activity in neocortical cells is inhibited by lithium but not carbamazepine or valproic acid. Bipolar Disord 2005, 7:260-265. 10.1111/j.1399-5618.2005.00194.x, 1249491, 15898963.
    • (2005) Bipolar Disord , vol.7 , pp. 260-265
    • Jonathan Ryves, W.1    Dalton, E.C.2    Harwood, A.J.3    Williams, R.S.4
  • 24
    • 33846095134 scopus 로고    scopus 로고
    • Lithium regulates glycogen synthase kinase-3β in human peripheral blood mononuclear cells: implication in the treatment of bipolar disorder
    • 10.1016/j.biopsych.2006.02.027, 1853347, 16806104
    • Li X, Friedman AB, Zhu W, Wang L, Boswell S, May RS, Davis LL, Jope RS. Lithium regulates glycogen synthase kinase-3β in human peripheral blood mononuclear cells: implication in the treatment of bipolar disorder. Biol Psychiatry 2007, 61:216-222. 10.1016/j.biopsych.2006.02.027, 1853347, 16806104.
    • (2007) Biol Psychiatry , vol.61 , pp. 216-222
    • Li, X.1    Friedman, A.B.2    Zhu, W.3    Wang, L.4    Boswell, S.5    May, R.S.6    Davis, L.L.7    Jope, R.S.8
  • 26
    • 39149087991 scopus 로고    scopus 로고
    • Effects of lithium and valproate on serum and hippocampal neurotrophin-3 levels in an animal model of mania
    • 10.1016/j.jpsychires.2007.03.005, 17512948
    • Walz JC, Frey BN, Andreazza AC, Cereser KM, Cacilhas AA, Valvassori SS, Quevedo J, Kapczinski F. Effects of lithium and valproate on serum and hippocampal neurotrophin-3 levels in an animal model of mania. J Psychiatr Res 2008, 42:416-421. 10.1016/j.jpsychires.2007.03.005, 17512948.
    • (2008) J Psychiatr Res , vol.42 , pp. 416-421
    • Walz, J.C.1    Frey, B.N.2    Andreazza, A.C.3    Cereser, K.M.4    Cacilhas, A.A.5    Valvassori, S.S.6    Quevedo, J.7    Kapczinski, F.8
  • 28
    • 0141927282 scopus 로고    scopus 로고
    • Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depression
    • 10.1017/S1461145703003468, 12974988
    • Angelucci F, Aloe L, Jimenez-Vasquez P, Mathe AA. Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depression. Int J Neuropsychopharmacol 2003, 6:225-231. 10.1017/S1461145703003468, 12974988.
    • (2003) Int J Neuropsychopharmacol , vol.6 , pp. 225-231
    • Angelucci, F.1    Aloe, L.2    Jimenez-Vasquez, P.3    Mathe, A.A.4
  • 29
    • 0036024262 scopus 로고    scopus 로고
    • Subchronic treatment with lithium increases nerve growth factor content in distinct brain regions of adult rats
    • 10.1038/sj.mp.4001042, 12140783
    • Hellweg R, Lang UE, Nagel M, Baumgartner A. Subchronic treatment with lithium increases nerve growth factor content in distinct brain regions of adult rats. Mol Psychiatry 2002, 7:604-608. 10.1038/sj.mp.4001042, 12140783.
    • (2002) Mol Psychiatry , vol.7 , pp. 604-608
    • Hellweg, R.1    Lang, U.E.2    Nagel, M.3    Baumgartner, A.4
  • 30
    • 0034795827 scopus 로고    scopus 로고
    • Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain
    • Fukumoto T, Morinobu S, Okamoto Y, Kagaya A, Yamawaki S. Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain. Psychopharmacology (Berl) 2001, 158:100-106.
    • (2001) Psychopharmacology (Berl) , vol.158 , pp. 100-106
    • Fukumoto, T.1    Morinobu, S.2    Okamoto, Y.3    Kagaya, A.4    Yamawaki, S.5
  • 31
    • 0036914074 scopus 로고    scopus 로고
    • Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity
    • 10.1016/S0028-3908(02)00217-4, 12504924
    • Hashimoto R, Takei N, Shimazu K, Christ L, Lu B, Chuang DM. Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity. Neuropharmacology 2002, 43:1173-1179. 10.1016/S0028-3908(02)00217-4, 12504924.
    • (2002) Neuropharmacology , vol.43 , pp. 1173-1179
    • Hashimoto, R.1    Takei, N.2    Shimazu, K.3    Christ, L.4    Lu, B.5    Chuang, D.M.6
  • 32
    • 33846670518 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is required for optimal de novo synthesis of inositol
    • 10.1111/j.1365-2958.2007.05591.x, 17257308
    • Azab AN, He Q, Ju S, Li G, Greenberg ML. Glycogen synthase kinase-3 is required for optimal de novo synthesis of inositol. Mol Microbiol 2007, 63:1248-1258. 10.1111/j.1365-2958.2007.05591.x, 17257308.
    • (2007) Mol Microbiol , vol.63 , pp. 1248-1258
    • Azab, A.N.1    He, Q.2    Ju, S.3    Li, G.4    Greenberg, M.L.5
  • 33
    • 11844297771 scopus 로고    scopus 로고
    • GSK-3β regulates phosphorylation of CRMP-2 and neuronal polarity
    • 10.1016/j.cell.2004.11.012, 15652488
    • Yoshimura T, Kawano Y, Arimura N, Kawabata S, Kikuchi A, Kaibuchi K. GSK-3β regulates phosphorylation of CRMP-2 and neuronal polarity. Cell 2005, 120:137-149. 10.1016/j.cell.2004.11.012, 15652488.
    • (2005) Cell , vol.120 , pp. 137-149
    • Yoshimura, T.1    Kawano, Y.2    Arimura, N.3    Kawabata, S.4    Kikuchi, A.5    Kaibuchi, K.6
  • 34
    • 11844260672 scopus 로고    scopus 로고
    • Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3β and its upstream regulators
    • Jiang H, Guo W, Liang X, Rao Y. Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3β and its upstream regulators. Cell 2005, 120:123-135.
    • (2005) Cell , vol.120 , pp. 123-135
    • Jiang, H.1    Guo, W.2    Liang, X.3    Rao, Y.4
  • 35
    • 0037118050 scopus 로고    scopus 로고
    • A common mechanism of action for three mood-stabilizing drugs
    • 10.1038/417292a, 12015604
    • Williams RS, Cheng L, Mudge AW, Harwood AJ. A common mechanism of action for three mood-stabilizing drugs. Nature 2002, 417:292-295. 10.1038/417292a, 12015604.
    • (2002) Nature , vol.417 , pp. 292-295
    • Williams, R.S.1    Cheng, L.2    Mudge, A.W.3    Harwood, A.J.4
  • 36
    • 35848967373 scopus 로고    scopus 로고
    • Targeting autophagic regulation of NF-kB in HTLV-I transformed cells by geldanamycin: implications for therapeutic interventions
    • Yan P, Qing G, Qu Z, Wu CC, Rabson A, Xiao G. Targeting autophagic regulation of NF-kB in HTLV-I transformed cells by geldanamycin: implications for therapeutic interventions. Autophagy 2007, 3:600-603.
    • (2007) Autophagy , vol.3 , pp. 600-603
    • Yan, P.1    Qing, G.2    Qu, Z.3    Wu, C.C.4    Rabson, A.5    Xiao, G.6
  • 37
    • 7244240800 scopus 로고    scopus 로고
    • Tax deregulation of NF-kB2 p100 processing involves both b-TrCP-dependent and -independent mechanisms
    • 10.1074/jbc.M403689200, 15310758
    • Qu Z, Qing G, Rabson A, Xiao G. Tax deregulation of NF-kB2 p100 processing involves both b-TrCP-dependent and -independent mechanisms. J Biol Chem 2004, 279:44563-44572. 10.1074/jbc.M403689200, 15310758.
    • (2004) J Biol Chem , vol.279 , pp. 44563-44572
    • Qu, Z.1    Qing, G.2    Rabson, A.3    Xiao, G.4
  • 38
    • 12844275943 scopus 로고    scopus 로고
    • Regulation of NF-κB2 p100 processing by its cis-acting domain
    • Qing G, Qu Z, Xiao G. Regulation of NF-κB2 p100 processing by its cis-acting domain. J Biol Chem 2005, 280:18-27.
    • (2005) J Biol Chem , vol.280 , pp. 18-27
    • Qing, G.1    Qu, Z.2    Xiao, G.3
  • 39
    • 79551625912 scopus 로고    scopus 로고
    • The tumor suppressor gene WWOX links the canonical and noncanonical NF-kB pathways in HTLV-I Tax-mediated tumorigenesis
    • 10.1182/blood-2010-08-303073, 21115974
    • Fu J, Qu Z, Yan P, Ishikawa C, Aqeilan RI, Rabson AB, Xiao G. The tumor suppressor gene WWOX links the canonical and noncanonical NF-kB pathways in HTLV-I Tax-mediated tumorigenesis. Blood 2011, 117:1652-1661. 10.1182/blood-2010-08-303073, 21115974.
    • (2011) Blood , vol.117 , pp. 1652-1661
    • Fu, J.1    Qu, Z.2    Yan, P.3    Ishikawa, C.4    Aqeilan, R.I.5    Rabson, A.B.6    Xiao, G.7
  • 40
    • 66149089133 scopus 로고    scopus 로고
    • PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation
    • 10.1182/blood-2008-10-185660, 2676091, 19131544
    • Yan P, Fu J, Qu Z, Li S, Tanaka T, Grusby MJ, Xiao G. PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation. Blood 2009, 113:4370-4380. 10.1182/blood-2008-10-185660, 2676091, 19131544.
    • (2009) Blood , vol.113 , pp. 4370-4380
    • Yan, P.1    Fu, J.2    Qu, Z.3    Li, S.4    Tanaka, T.5    Grusby, M.J.6    Xiao, G.7
  • 41
    • 77951236061 scopus 로고    scopus 로고
    • Epigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer
    • 10.1074/jbc.M109.086561, 2852914, 20185823
    • Qu Z, Fu J, Yan P, Hu J, Cheng SY, Xiao G. Epigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer. J Biol Chem 2010, 285:11786-11792. 10.1074/jbc.M109.086561, 2852914, 20185823.
    • (2010) J Biol Chem , vol.285 , pp. 11786-11792
    • Qu, Z.1    Fu, J.2    Yan, P.3    Hu, J.4    Cheng, S.Y.5    Xiao, G.6
  • 42
    • 34248371224 scopus 로고    scopus 로고
    • Endoproteolytic processing of C-terminally truncated NF-kB2 precursors at kappaB-containing promoters
    • 10.1073/pnas.0609914104, 1838492, 17363471
    • Qing G, Qu Z, Xiao G. Endoproteolytic processing of C-terminally truncated NF-kB2 precursors at kappaB-containing promoters. Proc Natl Acad Sci USA 2007, 104:5324-5329. 10.1073/pnas.0609914104, 1838492, 17363471.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5324-5329
    • Qing, G.1    Qu, Z.2    Xiao, G.3
  • 43
    • 77950193822 scopus 로고    scopus 로고
    • DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target
    • 10.1158/0008-5472.CAN-09-3263, 3003295, 20145149
    • Qu Z, Yan P, Fu J, Jiang J, Grusby MJ, Smithgall TE, Xiao G. DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target. Cancer Res 2010, 70:1766-1772. 10.1158/0008-5472.CAN-09-3263, 3003295, 20145149.
    • (2010) Cancer Res , vol.70 , pp. 1766-1772
    • Qu, Z.1    Yan, P.2    Fu, J.3    Jiang, J.4    Grusby, M.J.5    Smithgall, T.E.6    Xiao, G.7


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