-
1
-
-
20544473037
-
Vaccinology at the beginning of the 21st century
-
Wack A, Rappuoli R. Vaccinology at the beginning of the 21st century. Curr. Opin. Immunol. 17(4), 411-418 (2005
-
(2005)
Curr. Opin. Immunol
, vol.17
, Issue.4
, pp. 411-418
-
-
Wack, A.1
Rappuoli, R.2
-
2
-
-
84862659753
-
Adjuvants for human vaccines
-
Alving CR, Peachman KK, Rao M, Reed SG. Adjuvants for human vaccines. Curr. Opin. Immunol. 24(3), 310-315 (2012
-
(2012)
Curr. Opin. Immunol
, vol.24
, Issue.3
, pp. 310-315
-
-
Alving, C.R.1
Peachman, K.K.2
Rao, M.3
Reed, S.G.4
-
3
-
-
77958047728
-
A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosis
-
Bertholet S, Ireton GC, Ordway DJ et al. A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosis. Sci. Transl. Med. 2(53), 53-74 (2010
-
(2010)
Sci. Transl. Med
, vol.2
, Issue.53
, pp. 53-74
-
-
Bertholet, S.1
Ireton, G.C.2
Ordway, D.J.3
-
4
-
-
78149457931
-
A synthetic adjuvant to enhance and expand immune responses to influenza vaccines
-
Coler RN, Baldwin SL, Shaverdian N et al. A synthetic adjuvant to enhance and expand immune responses to influenza vaccines. PLoS ONE 5(10), e13677 (2010
-
(2010)
PLoS ONE
, vol.5
, Issue.10
-
-
Coler, R.N.1
Baldwin, S.L.2
Shaverdian, N.3
-
5
-
-
0001295075
-
Studies on the o antigen of salmonella ryphosa v enhancement of antibody response to protein antigens by purified lipopolysaccharide
-
Johnson AG, Gains S, Landy M. Studies on the O antigen of Salmonella ryphosa V. Enhancement of antibody response to protein antigens by purified lipopolysaccharide. J. Exp. Med. 103(2), 225-246 (1956
-
(1956)
J. Exp. Med
, vol.103
, Issue.2
, pp. 225-246
-
-
Johnson, A.G.1
Gains, S.2
Landy, M.3
-
6
-
-
0022979170
-
Immunobiological activities of synthetic lipid A analogs with low endotoxicity
-
Kotani S, Takada H, Takahashi I et al. Immunobiological activities of synthetic lipid A analogs with low endotoxicity. Infect. Immun. 54(3), 673-682 (1986
-
(1986)
Infect. Immun
, vol.54
, Issue.3
, pp. 673-682
-
-
Kotani, S.1
Takada, H.2
Takahashi, I.3
-
7
-
-
0021821427
-
Synthetic lipid A with endotoxic and related biological activities comparable to those of a natural lipid A from an Escherichia coli re-mutant
-
Kotani S, Takada H, Tsujimoto M et al. Synthetic lipid A with endotoxic and related biological activities comparable to those of a natural lipid A from an Escherichia coli re-mutant. Infect. Immun. 49(1), 225-237 (1985
-
(1985)
Infect. Immun
, vol.49
, Issue.1
, pp. 225-237
-
-
Kotani, S.1
Takada, H.2
Tsujimoto, M.3
-
8
-
-
84872861418
-
Modulating the innate immune response by combinatorial engineering of endotoxin
-
Needham BD, Carroll SM, Giles DK, Georgiou G, Whiteley M, Trent MS. Modulating the innate immune response by combinatorial engineering of endotoxin. Proc. Natl Acad. Sci. USA 110(4), 1464-1469 (2013
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, Issue.4
, pp. 1464-1469
-
-
Needham, B.D.1
Carroll, S.M.2
Giles, D.K.3
Georgiou, G.4
Whiteley, M.5
Trent, M.S.6
-
10
-
-
35349016235
-
Recognition of microorganisms and activation of the immune response
-
Medzhitov R. Recognition of microorganisms and activation of the immune response. Nature 449(7164), 819-826 (2007
-
(2007)
Nature
, vol.449
, Issue.7164
, pp. 819-826
-
-
Medzhitov, R.1
-
11
-
-
65649141586
-
Pathogen recognition in the innate immune response
-
Kumar H, Kawai T, Akira S. Pathogen recognition in the innate immune response. Biochem. J. 420(1), 1-16 (2009
-
(2009)
Biochem. J.
, vol.420
, Issue.1
, pp. 1-16
-
-
Kumar, H.1
Kawai, T.2
Akira, S.3
-
12
-
-
84867427919
-
Sensing of microbial molecular patterns by Toll-like receptors
-
Song DH, Lee JO. Sensing of microbial molecular patterns by Toll-like receptors. Immunol. Rev. 250(1), 216-229 (2012
-
(2012)
Immunol. Rev
, vol.250
, Issue.1
, pp. 216-229
-
-
Song, D.H.1
Lee, J.O.2
-
13
-
-
61849170035
-
TLRs and innate immunity
-
Beutler BA. TLRs and innate immunity. Blood 113(7), 1399-1407 (2009
-
(2009)
Blood
, vol.113
, Issue.7
, pp. 1399-1407
-
-
Beutler, B.A.1
-
14
-
-
16644366474
-
Toll-like receptors: Linking innate and adaptive immunity
-
Pasare C, Medzhitov R. Toll-like receptors: Linking innate and adaptive immunity. Microbes Infect. 6(15), 1382-1387 (2004
-
(2004)
Microbes Infect
, vol.6
, Issue.15
, pp. 1382-1387
-
-
Pasare, C.1
Medzhitov, R.2
-
15
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388(6640), 394-397 (1997
-
(1997)
Nature
, vol.388
, Issue.6640
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
16
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science 282(5396), 2085-2088 (1998
-
(1998)
Science
, vol.282
, Issue.5396
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
-
17
-
-
0030595339
-
The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA. The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86(6), 973-983 (1996
-
(1996)
Cell
, vol.86
, Issue.6
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
18
-
-
34347209992
-
Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate Toll-like receptors
-
Matsushima N, Tanaka T, Enkhbayar P et al. Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate Toll-like receptors. BMC Genomics 8, 124 (2007
-
(2007)
BMC Genomics
, vol.8
, pp. 124
-
-
Matsushima, N.1
Tanaka, T.2
Enkhbayar, P.3
-
19
-
-
63649108380
-
The roles of TLRs RLRs and NLRs in pathogen recognition
-
Kawai T, Akira S. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int. Immunol. 21(4), 317-337 (2009
-
(2009)
Int. Immunol
, vol.21
, Issue.4
, pp. 317-337
-
-
Kawai, T.1
Akira, S.2
-
20
-
-
40949134086
-
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
-
Kagan JC, Su T, Horng T, Chow A, Akira S, Medzhitov R. TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β. Nat. Immunol. 9(4), 361-368 (2008
-
(2008)
Nat. Immunol
, vol.9
, Issue.4
, pp. 361-368
-
-
Kagan, J.C.1
Su, T.2
Horng, T.3
Chow, A.4
Akira, S.5
Medzhitov, R.6
-
21
-
-
34548608447
-
Crystal structure of the tlr1-Tlr2 heterodimer induced by binding of a tri-Acylated lipopeptide
-
Jin MS, Kim SE, Heo JY et al. Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-Acylated lipopeptide. Cell 130(6), 1071-1082 (2007
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1071-1082
-
-
Jin, M.S.1
Kim, S.E.2
Heo, J.Y.3
-
22
-
-
42349090335
-
Structural basis of Toll-like receptor 3 signaling with double-stranded RNA
-
Liu L, Botos I, Wang Y et al. Structural basis of Toll-like receptor 3 signaling with double-stranded RNA. Science 320(5874), 379-381 (2008
-
(2008)
Science
, vol.320
, Issue.5874
, pp. 379-381
-
-
Liu, L.1
Botos, I.2
Wang, Y.3
-
23
-
-
67349182481
-
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
-
Park BS, Song DH, Kim HM, Choi BS, Lee H, Lee JO. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature 458(7242), 1191-1195 (2009
-
(2009)
Nature
, vol.458
, Issue.7242
, pp. 1191-1195
-
-
Park, B.S.1
Song, D.H.2
Kim, H.M.3
Choi, B.S.4
Lee, H.5
Lee, J.O.6
-
24
-
-
28844449649
-
Expression of Toll-like receptors on B lymphocytes
-
Dasari P, Nicholson IC, Hodge G, Dandie GW, Zola H. Expression of Toll-like receptors on B lymphocytes. Cell. Immunol. 236(1-2), 140-145 (2005
-
(2005)
Cell. Immunol
, vol.236
, Issue.1-2
, pp. 140-145
-
-
Dasari, P.1
Nicholson, I.C.2
Hodge, G.3
Dandie, G.W.4
Zola, H.5
-
25
-
-
55049110418
-
No longer an innocent bystander: Epithelial Toll-like receptor signaling in the development of mucosal inflammation
-
Gribar SC, Richardson WM, Sodhi CP, Hackam DJ. No longer an innocent bystander: Epithelial Toll-like receptor signaling in the development of mucosal inflammation. Mol. Med. 14(9-10), 645-659 (2008
-
(2008)
Mol. Med
, vol.14
, Issue.9-10
, pp. 645-659
-
-
Gribar, S.C.1
Richardson, W.M.2
Sodhi, C.P.3
Hackam, D.J.4
-
26
-
-
20444387233
-
Mycobacterium tuberculosis heat shock proteins use diverse Toll-like receptor pathways to activate pro-inflammatory signals
-
Bulut Y, Michelsen KS, Hayrapetian L et al. Mycobacterium tuberculosis heat shock proteins use diverse Toll-like receptor pathways to activate pro-inflammatory signals. J. Biol. Chem. 280(22), 20961-20967 (2005
-
(2005)
J. Biol. Chem
, vol.280
, Issue.22
, pp. 20961-20967
-
-
Bulut, Y.1
Michelsen, K.S.2
Hayrapetian, L.3
-
27
-
-
34247566510
-
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
-
O'Neill LA, Bowie AG. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat. Rev. Immunol. 7(5), 353-364 (2007
-
(2007)
Nat. Rev. Immunol
, vol.7
, Issue.5
, pp. 353-364
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
28
-
-
67649422321
-
Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer
-
O'Neill LA, Bryant CE, Doyle SL. Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer. Pharmacol. Rev. 61(2), 177-197 (2009
-
(2009)
Pharmacol. Rev
, vol.61
, Issue.2
, pp. 177-197
-
-
O'Neill, L.A.1
Bryant, C.E.2
Doyle, S.L.3
-
29
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 124(4), 783-801 (2006
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
30
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S, Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 4(7), 499-511 (2004
-
(2004)
Nat. Rev. Immunol
, vol.4
, Issue.7
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
31
-
-
68849085894
-
A cell biological view of Toll-like receptor function: Regulation through compartmentalization
-
Barton GM, Kagan JC. A cell biological view of Toll-like receptor function: Regulation through compartmentalization. Nat. Rev. Immunol. 9(8), 535-542 (2009
-
(2009)
Nat. Rev. Immunol
, vol.9
, Issue.8
, pp. 535-542
-
-
Barton, G.M.1
Kagan, J.C.2
-
32
-
-
0036083905
-
Exploiting dendritic cells to improve vaccine efficacy
-
Steinman RM, Pope M. Exploiting dendritic cells to improve vaccine efficacy. J. Clin. Invest. 109(12), 1519-1526 (2002
-
(2002)
J. Clin. Invest
, vol.109
, Issue.12
, pp. 1519-1526
-
-
Steinman, R.M.1
Pope, M.2
-
33
-
-
79551551963
-
Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant
-
Coler RN, Bertholet S, Moutaftsi M et al. Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant. PLoS ONE 6(1), e16333 (2011
-
(2011)
PLoS ONE
, vol.6
, Issue.1
-
-
Coler, R.N.1
Bertholet, S.2
Moutaftsi, M.3
-
34
-
-
77954679956
-
Release of IL-12 by dendritic cells activated by TLR ligation is dependent on MyD88 signaling, whereas TRIF signaling is indispensable for TLR synergy
-
Krummen M, Balkow S, Shen L et al. Release of IL-12 by dendritic cells activated by TLR ligation is dependent on MyD88 signaling, whereas TRIF signaling is indispensable for TLR synergy. J. Leukoc. Biol. 88(1), 189-199 (2010
-
(2010)
J. Leukoc. Biol
, vol.88
, Issue.1
, pp. 189-199
-
-
Krummen, M.1
Balkow, S.2
Shen, L.3
-
35
-
-
49649109586
-
Dual signaling of MyD88 and TRIF is critical for maximal TLR4-induced dendritic cell maturation
-
Shen H, Tesar BM, Walker WE, Goldstein DR. Dual signaling of MyD88 and TRIF is critical for maximal TLR4-induced dendritic cell maturation. J. Immunol. 181(3), 1849-1858 (2008
-
(2008)
J. Immunol
, vol.181
, Issue.3
, pp. 1849-1858
-
-
Shen, H.1
Tesar, B.M.2
Walker, W.E.3
Goldstein, D.R.4
-
36
-
-
23944489407
-
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
-
Napolitani G, Rinaldi A, Bertoni F, Sallusto F, Lanzavecchia A. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat. Immunol. 6(8), 769-776 (2005
-
(2005)
Nat. Immunol
, vol.6
, Issue.8
, pp. 769-776
-
-
Napolitani, G.1
Rinaldi, A.2
Bertoni, F.3
Sallusto, F.4
Lanzavecchia, A.5
-
38
-
-
0021798736
-
Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities
-
Galanos C, Lüderitz O, Rietschel ET et al. Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities. Eur. J. Biochem. 148(1), 1-5 (1985
-
(1985)
Eur. J. Biochem
, vol.148
, Issue.1
, pp. 1-5
-
-
Galanos, C.1
Lüderitz, O.2
Rietschel, E.T.3
-
39
-
-
33749065328
-
Roles for accessory molecules in microbial recognition by Toll-like receptors
-
Miyake K. Roles for accessory molecules in microbial recognition by Toll-like receptors. J. Endotoxin Res. 12(4), 195-204 (2006
-
(2006)
J. Endotoxin Res
, vol.12
, Issue.4
, pp. 195-204
-
-
Miyake, K.1
-
40
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
Nagai Y, Akashi S, Nagafuku M et al. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat. Immunol. 3(7), 667-672 (2002
-
(2002)
Nat. Immunol
, vol.3
, Issue.7
, pp. 667-672
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
-
41
-
-
33646494167
-
Regulatory roles for MD-2 and TLR4 in ligand-induced receptor clustering
-
Kobayashi M, Saitoh S, Tanimura N et al. Regulatory roles for MD-2 and TLR4 in ligand-induced receptor clustering. J. Immunol. 176(10), 6211-6218 (2006
-
(2006)
J. Immunol
, vol.176
, Issue.10
, pp. 6211-6218
-
-
Kobayashi, M.1
Saitoh, S.2
Tanimura, N.3
-
42
-
-
0028085132
-
Bacterial endotoxin: Molecular relationships of structure to activity and function
-
Rietschel ET, Kirikae T, Schade FU et al. Bacterial endotoxin: Molecular relationships of structure to activity and function. FASEB J. 8(2), 217-225 (1994
-
(1994)
FASEB J.
, vol.8
, Issue.2
, pp. 217-225
-
-
Rietschel, E.T.1
Kirikae, T.2
Schade, F.U.3
-
43
-
-
0021994587
-
B cell activation and adjuvant activities of chemically synthesized analogues of the nonreducing sugar moiety of lipid A
-
Kumazawa Y, Matsuura M, Homma JY, Nakatsuru Y, Kiso M, Hasegawa A. B cell activation and adjuvant activities of chemically synthesized analogues of the nonreducing sugar moiety of lipid A. Eur. J. Immunol. 15(2), 199-201 (1985
-
(1985)
Eur. J. Immunol
, vol.15
, Issue.2
, pp. 199-201
-
-
Kumazawa, Y.1
Matsuura, M.2
Homma, J.Y.3
Nakatsuru, Y.4
Kiso, M.5
Hasegawa, A.6
-
44
-
-
0025285857
-
Biochemistry of endotoxins
-
Raetz CR. Biochemistry of endotoxins. Annu. Rev. Biochem. 59, 129-170 (1990
-
(1990)
Annu. Rev. Biochem
, vol.59
, pp. 129-170
-
-
Raetz, C.R.1
-
45
-
-
0034820507
-
Bacterial lipopolysaccharides and innate immunity
-
Alexander C, Rietschel ET. Bacterial lipopolysaccharides and innate immunity. J. Endotoxin Res. 7(3), 167-202 (2001
-
(2001)
J. Endotoxin Res
, vol.7
, Issue.3
, pp. 167-202
-
-
Alexander, C.1
Rietschel, E.T.2
-
46
-
-
0036222620
-
Human Toll-like receptor 4 recognizes host-specific LPS modifications
-
Hajjar AM, Ernst RK, Tsai JH, Wilson CB, Miller SI. Human Toll-like receptor 4 recognizes host-specific LPS modifications. Nat. Immunol. 3(4), 354-359 (2002
-
(2002)
Nat. Immunol
, vol.3
, Issue.4
, pp. 354-359
-
-
Hajjar, A.M.1
Ernst, R.K.2
Tsai, J.H.3
Wilson, C.B.4
Miller, S.I.5
-
47
-
-
0347659154
-
Structural basis for endotoxic and antagonistic activities: Investigation with novel synthetic lipid A analogs
-
Kusumoto S, Fukase K, Fukase Y et al. Structural basis for endotoxic and antagonistic activities: Investigation with novel synthetic lipid A analogs. J. Endotoxin Res. 9(6), 361-366 (2003
-
(2003)
J. Endotoxin Res
, vol.9
, Issue.6
, pp. 361-366
-
-
Kusumoto, S.1
Fukase, K.2
Fukase, Y.3
-
48
-
-
84868089513
-
Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica
-
Hajjar AM, Ernst RK, Fortuno ES 3rd et al. Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica. PLoS Pathog. 8(10), e1002963 (2012
-
(2012)
PLoS Pathog
, vol.8
, Issue.10
-
-
Hajjar, A.M.1
Ernst, R.K.2
Fortuno III, E.S.3
-
49
-
-
0033523944
-
3-O-Desacyl monophosphoryl lipid A derivatives: Synthesis and immunostimulant activities
-
Johnson DA, Keegan DS, Sowell CG et al. 3-O-Desacyl monophosphoryl lipid A derivatives: Synthesis and immunostimulant activities. J. Med. Chem. 42(22), 4640-4649 (1999
-
(1999)
J. Med. Chem
, vol.42
, Issue.22
, pp. 4640-4649
-
-
Johnson, D.A.1
Keegan, D.S.2
Sowell, C.G.3
-
50
-
-
2442499153
-
Structure-Activity relationship of synthetic Toll-like receptor 4 agonists
-
Stöver AG, Da Silva Correia J, Evans JT et al. Structure-Activity relationship of synthetic Toll-like receptor 4 agonists. J. Biol. Chem. 279(6), 4440-4449 (2004
-
(2004)
J. Biol. Chem
, vol.279
, Issue.6
, pp. 4440-4449
-
-
Stöver, A.G.1
Da Silva Correia, J.2
Evans, J.T.3
-
51
-
-
70450253086
-
Selective activation of the p38 MAPK pathway by synthetic monophosphoryl lipid A
-
Cekic C, Casella CR, Eaves CA, Matsuzawa A, Ichijo H, Mitchell TC. Selective activation of the p38 MAPK pathway by synthetic monophosphoryl lipid A. J. Biol. Chem. 284(46), 31982-31991 (2009
-
(2009)
J. Biol. Chem
, vol.284
, Issue.46
, pp. 31982-31991
-
-
Cekic, C.1
Casella, C.R.2
Eaves, C.A.3
Matsuzawa, A.4
Ichijo, H.5
Mitchell, T.C.6
-
52
-
-
19944431880
-
Physicochemical characterization of carboxymethyl lipid A derivatives in relation to biological activity
-
Seydel U, Schromm AB, Brade L et al. Physicochemical characterization of carboxymethyl lipid A derivatives in relation to biological activity. FEBS J. 272(2), 327-340 (2005
-
(2005)
FEBS J.
, vol.272
, Issue.2
, pp. 327-340
-
-
Seydel, U.1
Schromm, A.B.2
Brade, L.3
-
53
-
-
0026632806
-
Biological activity of synthetic phosphonooxyethyl analogs of lipid A and lipid A partial structures
-
Ulmer AJ, Heine H, Feist W et al. Biological activity of synthetic phosphonooxyethyl analogs of lipid A and lipid A partial structures. Infect. Immun. 60(8), 3309-3314 (1992
-
(1992)
Infect. Immun
, vol.60
, Issue.8
, pp. 3309-3314
-
-
Ulmer, A.J.1
Heine, H.2
Feist, W.3
-
54
-
-
34250854079
-
The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4
-
Mata-Haro V, Cekic C, Martin M, Chilton PM, Casella CR, Mitchell TC The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4. Science 316(5831), 1628-1632 (2007
-
(2007)
Science
, vol.316
, Issue.5831
, pp. 1628-1632
-
-
Mata-Haro, V.1
Cekic, C.2
Martin, M.3
Chilton, P.M.4
Casella, C.R.5
Mitchell, T.C.6
-
55
-
-
84857164217
-
Selective TRIF-dependent signaling by a synthetic Toll-like receptor 4 agonist
-
Bowen WS, Minns LA, Johnson DA, Mitchell TC, Hutton MM, Evans JT. Selective TRIF-dependent signaling by a synthetic Toll-like receptor 4 agonist. Sci. Signal. 5(211), ra13 (2012
-
(2012)
Sci. Signal
, vol.5
, Issue.211
-
-
Bowen, W.S.1
Minns, L.A.2
Johnson, D.A.3
Mitchell, T.C.4
Hutton, M.M.5
Evans, J.T.6
-
56
-
-
79955041562
-
MyD88-dependent SHIP1 regulates proinflammatory signaling pathways in dendritic cells after monophosphoryl lipid A stimulation of TLR4
-
Cekic C, Casella CR, Sag D et al. MyD88-dependent SHIP1 regulates proinflammatory signaling pathways in dendritic cells after monophosphoryl lipid A stimulation of TLR4. J. Immunol. 186(7), 3858-3865 (2011
-
(2011)
J Immunol
, vol.186
, Issue.7
, pp. 3858-3865
-
-
Cekic, C.1
Casella, C.R.2
Sag, D.3
-
57
-
-
34548222514
-
Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran
-
Kim HM, Park BS, Kim JI et al. Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran. Cell 130(5), 906-917 (2007
-
(2007)
Cell
, vol.130
, Issue.5
, pp. 906-917
-
-
Kim, H.M.1
Park, B.S.2
Kim, J.I.3
-
58
-
-
34250813748
-
Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa
-
Ohto U, Fukase K, Miyake K, Satow Y. Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa. Science 316(5831), 1632-1634 (2007
-
(2007)
Science
, vol.316
, Issue.5831
, pp. 1632-1634
-
-
Ohto, U.1
Fukase, K.2
Miyake, K.3
Satow, Y.4
-
59
-
-
23044445303
-
Crystal structure of human Toll-like receptor 3 (TLR3) ectodomain
-
Choe J, Kelker MS, Wilson IA. Crystal structure of human Toll-like receptor 3 (TLR3) ectodomain. Science 309(5734), 581-585 (2005
-
(2005)
Science
, vol.309
, Issue.5734
, pp. 581-585
-
-
Choe, J.1
Kelker, M.S.2
Wilson, I.A.3
-
60
-
-
71749118913
-
Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
-
Kang JY, Nan X, Jin MS et al. Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer. Immunity 31(6), 873-884 (2009
-
(2009)
Immunity
, vol.31
, Issue.6
, pp. 873-884
-
-
Kang, J.Y.1
Nan, X.2
Jin, M.S.3
-
61
-
-
84860832650
-
Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
-
Ohto U, Fukase K, Miyake K, Shimizu T. Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2. Proc. Natl Acad. Sci. USA 109(19), 7421-7426 (2012
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, Issue.19
, pp. 7421-7426
-
-
Ohto, U.1
Fukase, K.2
Miyake, K.3
Shimizu, T.4
-
62
-
-
84895077276
-
Peptides as requirement for immunotherapy of the guinea-pig line 10 tumor with endotoxins
-
Ribi E, Parker R, Strain S et al. Peptides as requirement for immunotherapy of the guinea-pig line 10 tumor with endotoxins. Cancer Immunol. Immunother. 12, 91-96 (1979
-
(1979)
Cancer Immunol. Immunother
, vol.12
, pp. 91-96
-
-
Ribi, E.1
Parker, R.2
Strain, S.3
-
63
-
-
0005202926
-
-
Nowotny A, Spitzler J, Ziegler E (Eds). Elsevier, Amsterdam, The Netherlands
-
Myers K, Truchot A, Ward J, Hudson Y, Ulrich J. A critical determinant of lipid A endotoxic activity. In: Cellular and Molecular Aspects of Endotoxin Reactions. Nowotny A, Spitzler J, Ziegler E (Eds). Elsevier, Amsterdam, The Netherlands, 145-156 (1990
-
(1990)
A Critical Determinant Of Lipid A Endotoxic Activity Cellular and Molecular Aspects of Endotoxin Reactions
, pp. 145-156
-
-
Myers, K.1
Truchot, A.2
Ward, J.3
Hudson, Y.4
Ulrich, J.5
-
64
-
-
0029201182
-
Monophosphoryl lipid A as an adjuvant
-
Powell M, Newman M (Eds). Plenum Press, New York, NY, USA
-
Ulrich J, Myers K. Monophosphoryl lipid A as an adjuvant. In: Vaccine Design: The Subunit and Adjuvant Approach. Powell M, Newman M (Eds). Plenum Press, New York, NY, USA, 495-524 (1995
-
(1995)
Vaccine Design: The Subunit and Adjuvant Approach
, pp. 495-524
-
-
Ulrich, J.1
Myers, K.2
-
65
-
-
53849109907
-
Putting endotoxin to work for us: Monophosphoryl lipid A as a safe and effective vaccine adjuvant
-
Casella CR, Mitchell TC. Putting endotoxin to work for us: Monophosphoryl lipid A as a safe and effective vaccine adjuvant. Cell. Mol. Life Sci. 65(20), 3231-3240 (2008
-
(2008)
Cell. Mol. Life Sci
, vol.65
, Issue.20
, pp. 3231-3240
-
-
Casella, C.R.1
Mitchell, T.C.2
-
66
-
-
0027322203
-
Interim results of a Phase II multicenter clinical trial evaluating the activity of a therapeutic allogeneic melanoma vaccine (theraccine) in the treatment of disseminated malignant melanoma
-
Elliott GT, McLeod RA, Perez J, Von Eschen KB. Interim results of a Phase II multicenter clinical trial evaluating the activity of a therapeutic allogeneic melanoma vaccine (theraccine) in the treatment of disseminated malignant melanoma. Semin. Surg. Oncol. 9(3), 264-272 (1993
-
(1993)
Semin. Surg. Oncol
, vol.9
, Issue.3
, pp. 264-272
-
-
Elliott, G.T.1
McLeod, R.A.2
Perez, J.3
Von Eschen, K.B.4
-
67
-
-
0025262476
-
Active-specific immunotherapy for melanoma
-
Mitchell MS, Harel W, Kempf RA et al. Active-specific immunotherapy for melanoma. J. Clin. Oncol. 8(5), 856-869 (1990
-
(1990)
J. Clin. Oncol
, vol.8
, Issue.5
, pp. 856-869
-
-
Mitchell, M.S.1
Harel, W.2
Kempf, R.A.3
-
68
-
-
0037654784
-
Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi.529
-
Evans JT, Cluff CW, Johnson DA, Lacy MJ, Persing DH, Baldridge Jr. Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi.529. Expert Rev. Vaccines 2(2), 219-229 (2003
-
(2003)
Expert Rev Vaccines
, vol.2
, Issue.2
, pp. 219-229
-
-
Evans, J.T.1
Cluff, C.W.2
Johnson, D.A.3
Lacy, M.J.4
Persing, D.H.5
Baldridge, J.R.6
-
69
-
-
84855309413
-
Cross-protective efficacy of HPV-16/18 AS04-Adjuvanted vaccine against cervical infection and precancer caused by non-vaccine oncogenic HPV types: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial
-
HPV PATRICIA Study Group
-
Wheeler CM, Castellsagué; X, Garland SM et al.; HPV PATRICIA Study Group. Cross-protective efficacy of HPV-16/18 AS04-Adjuvanted vaccine against cervical infection and precancer caused by non-vaccine oncogenic HPV types: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial. Lancet Oncol. 13(1), 100-110 (2012
-
(2012)
Lancet Oncol
, vol.13
, Issue.1
, pp. 100-110
-
-
Wheeler, C.M.1
Castellsague, X.2
Garland, S.M.3
-
70
-
-
77249176352
-
AS04, an aluminum salt-And TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity
-
Didierlaurent AM, Morel S, Lockman L et al. AS04, an aluminum salt-And TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity. J. Immunol. 183(10), 6186-6197 (2009
-
(2009)
J. Immunol
, vol.183
, Issue.10
, pp. 6186-6197
-
-
Didierlaurent, A.M.1
Morel, S.2
Lockman, L.3
-
71
-
-
85040956318
-
Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02(D) malaria vaccine in infants living in a malaria-endemic region
-
Abdulla S, Salim N, Machera F et al. Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02(D) malaria vaccine in infants living in a malaria-endemic region. Malar. J. 12, 11 (2013
-
(2013)
Malar. J.
, vol.12
, pp. 11
-
-
Abdulla, S.1
Salim, N.2
Machera, F.3
-
72
-
-
84871037616
-
A Phase 3 trial of RTS,S/AS01 malaria vaccine in African infants
-
Agnandji ST, Lell B, Fernandes JF et al. A Phase 3 trial of RTS,S/AS01 malaria vaccine in African infants. N. Engl. J. Med. 367(24), 2284-2295 (2012
-
(2012)
N. Engl. J. Med
, vol.367
, Issue.24
, pp. 2284-2295
-
-
Agnandji, S.T.1
Lell, B.2
Fernandes, J.F.3
-
73
-
-
0028200604
-
Molecular adjuvants and immunomodulators: New approaches to immunization
-
Johnson AG. Molecular adjuvants and immunomodulators: New approaches to immunization. Clin. Microbiol. Rev. 7(3), 277-289 (1994
-
(1994)
Clin. Microbiol. Rev
, vol.7
, Issue.3
, pp. 277-289
-
-
Johnson, A.G.1
-
74
-
-
0022979341
-
Biological activity of synthetic heptaacyl lipid a representing a component of salmonella minnesota r595 lipid a
-
Galanos C, Lüderitz O, Freudenberg M et al. Biological activity of synthetic heptaacyl lipid A representing a component of Salmonella minnesota R595 lipid A. Eur. J. Biochem. 160(1), 55-59 (1986
-
(1986)
Eur. J. Biochem
, vol.160
, Issue.1
, pp. 55-59
-
-
Galanos, C.1
Lüderitz, O.2
Freudenberg, M.3
-
75
-
-
33847204580
-
Monophosphoryl lipid A analogues with varying 3-O-substitution: Synthesis and potent adjuvant activity
-
Jiang ZH, Budzynski WA, Qiu D, Yalamati D, Koganty RR. Monophosphoryl lipid A analogues with varying 3-O-substitution: Synthesis and potent adjuvant activity. Carbohydr. Res. 342(6), 784-796 (2007
-
(2007)
Carbohydr. Res
, vol.342
, Issue.6
, pp. 784-796
-
-
Jiang, Z.H.1
Budzynski, W.A.2
Qiu, D.3
Yalamati, D.4
Koganty, R.R.5
-
76
-
-
0037136008
-
Lipid A structures containing novel lipid moieties: Synthesis and adjuvant properties
-
Jiang ZH, Bach MV, Budzynski WA, Krantz MJ, Koganty RR, Longenecker BM. Lipid A structures containing novel lipid moieties: Synthesis and adjuvant properties. Bioorg. Med. Chem. Lett. 12(16), 2193-2196 (2002
-
(2002)
Bioorg. Med. Chem. Lett
, vol.12
, Issue.16
, pp. 2193-2196
-
-
Jiang, Z.H.1
Bach, M.V.2
Budzynski, W.A.3
Krantz, M.J.4
Koganty, R.R.5
Longenecker, B.M.6
-
77
-
-
33749241100
-
Synthesis and immunobiological activity of an original series of acyclic lipid a mimics based on a pseudodipeptide backbone
-
Martin OR, Zhou W, Wu X et al. Synthesis and immunobiological activity of an original series of acyclic lipid a mimics based on a pseudodipeptide backbone. J. Med. Chem. 49(20), 6000-6014 (2006
-
(2006)
J. Med. Chem
, vol.49
, Issue.20
, pp. 6000-6014
-
-
Martin, O.R.1
Zhou, W.2
Wu, X.3
-
78
-
-
35349002727
-
E6020: A synthetic Toll-like receptor 4 agonist as a vaccine adjuvant
-
Ishizaka ST, Hawkins LD. E6020: A synthetic Toll-like receptor 4 agonist as a vaccine adjuvant. Expert Rev. Vaccines 6(5), 773-784 (2007
-
(2007)
Expert Rev. Vaccines
, vol.6
, Issue.5
, pp. 773-784
-
-
Ishizaka, S.T.1
Hawkins, L.D.2
-
79
-
-
37349033531
-
Synthetic Toll-like receptor 4 agonist enhances vaccine efficacy in an experimental model of toxic shock syndrome
-
Morefield GL, Hawkins LD, Ishizaka ST, Kissner TL, Ulrich RG. Synthetic Toll-like receptor 4 agonist enhances vaccine efficacy in an experimental model of toxic shock syndrome. Clin. Vaccine Immunol. 14(11), 1499-1504 (2007
-
(2007)
Clin. Vaccine Immunol
, vol.14
, Issue.11
, pp. 1499-1504
-
-
Morefield, G.L.1
Hawkins, L.D.2
Ishizaka, S.T.3
Kissner, T.L.4
Ulrich, R.G.5
-
80
-
-
84857482098
-
The importance of adjuvant formulation in the development of a tuberculosis vaccine
-
Baldwin SL, Bertholet S, Reese VA, Ching LK, Reed SG, Coler RN. The importance of adjuvant formulation in the development of a tuberculosis vaccine. J. Immunol. 188(5), 2189-2197 (2012
-
(2012)
J. Immunol
, vol.188
, Issue.5
, pp. 2189-2197
-
-
Baldwin, S.L.1
Bertholet, S.2
Reese, V.A.3
Ching, L.K.4
Reed, S.G.5
Coler, R.N.6
-
81
-
-
79960800986
-
Targeting TLRs expands the antibody repertoire in response to a malaria vaccine
-
93ra69
-
Wiley SR, Raman VS, Desbien A et al. Targeting TLRs expands the antibody repertoire in response to a malaria vaccine. Sci. Transl. Med. 3(93), 93ra69 (2011
-
(2011)
Sci. Transl. Med
, vol.3
, Issue.93
-
-
Wiley, S.R.1
Raman, V.S.2
Desbien, A.3
-
82
-
-
2942746424
-
Aggregates are the biologically active units of endotoxin
-
Mueller M, Lindner B, Kusumoto S, Fukase K, Schromm AB, Seydel U. Aggregates are the biologically active units of endotoxin. J. Biol. Chem. 279(25), 26307-26313 (2004
-
(2004)
J. Biol. Chem
, vol.279
, Issue.25
, pp. 26307-26313
-
-
Mueller, M.1
Lindner, B.2
Kusumoto, S.3
Fukase, K.4
Schromm, A.B.5
Seydel, U.6
-
83
-
-
70449627069
-
Physicochemical characterization and biological activity of synthetic TLR4 agonist formulations
-
Anderson RC, Fox CB, Dutill TS et al. Physicochemical characterization and biological activity of synthetic TLR4 agonist formulations. Colloids Surf. B. Biointerfaces 75(1), 123-132 (2010
-
(2010)
Colloids Surf. B. Biointerfaces
, vol.75
, Issue.1
, pp. 123-132
-
-
Anderson, R.C.1
Fox, C.B.2
Dutill, T.S.3
-
84
-
-
0032755036
-
Monophosphoryl lipid A (MPL) formulations for the next generation of vaccines
-
Baldridge JR, Crane RT. Monophosphoryl lipid A (MPL) formulations for the next generation of vaccines. Methods 19(1), 103-107 (1999
-
(1999)
Methods
, vol.19
, Issue.1
, pp. 103-107
-
-
Baldridge, J.R.1
Crane, R.T.2
-
85
-
-
0033805905
-
Adjuvant activity of monophosphoryl lipid A for nasal and oral immunization with soluble or liposome-Associated antigen
-
Childers NK, Miller KL, Tong G et al. Adjuvant activity of monophosphoryl lipid A for nasal and oral immunization with soluble or liposome-Associated antigen. Infect. Immun. 68(10), 5509-5516 (2000
-
(2000)
Infect. Immun
, vol.68
, Issue.10
, pp. 5509-5516
-
-
Childers, N.K.1
Miller, K.L.2
Tong, G.3
-
86
-
-
58149216348
-
New horizons in adjuvants for vaccine development
-
Reed SG, Bertholet S, Coler RN, Friede M. New horizons in adjuvants for vaccine development. Trends Immunol. 30(1), 23-32 (2009
-
(2009)
Trends Immunol
, vol.30
, Issue.1
, pp. 23-32
-
-
Reed, S.G.1
Bertholet, S.2
Coler, R.N.3
Friede, M.4
-
87
-
-
43449121224
-
Adjuvant formulations possess differing efficacy in the potentiation of antibody and cell mediated responses to a human malaria vaccine under selective immune genes knockout environment
-
Hui GS, Hashimoto CN. Adjuvant formulations possess differing efficacy in the potentiation of antibody and cell mediated responses to a human malaria vaccine under selective immune genes knockout environment. Int. Immunopharmacol. 8(7), 1012-1022 (2008
-
(2008)
Int. Immunopharmacol
, vol.8
, Issue.7
, pp. 1012-1022
-
-
Hui, G.S.1
Hashimoto, C.N.2
-
88
-
-
0037205084
-
The global impact of vaccines containing aluminium adjuvants
-
Clements CJ, Griffiths E. The global impact of vaccines containing aluminium adjuvants. Vaccine 20(Suppl. 3), S24-S33 (2002
-
(2002)
Vaccine
, vol.20
, Issue.SUPPL. 3
-
-
Clements, C.J.1
Griffiths, E.2
-
89
-
-
35348968868
-
Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation
-
Hem SL, Hogenesch H. Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation. Expert Rev. Vaccines 6(5), 685-698 (2007
-
(2007)
Expert Rev. Vaccines
, vol.6
, Issue.5
, pp. 685-698
-
-
Hem, S.L.1
Hogenesch, H.2
-
90
-
-
44349121005
-
Design and selection of vaccine adjuvants: Principles and practice
-
Kaufmann SHE, Lambert PH (Eds Birkhauser Verlag, Basel, Switzerland
-
Alving CR, Matyas GR. Design and selection of vaccine adjuvants: Principles and practice. In: The Grand Challenge for the Future: Vaccines for Poverty-Related Diseases from Bench to Field. Kaufmann SHE, Lambert PH (Eds). Birkhauser Verlag, Basel, Switzerland, 99-118 (2005
-
(2005)
Grand Challenge for the Future: Vaccines for Poverty-Related Diseases from Bench to Field
, pp. 99-118
-
-
Alving, C.R.1
Matyas, G.R.2
-
91
-
-
65049091202
-
Development of a direct alhydrogel formulation immunoassay (DAFIA
-
Zhu D, Huang S, Gebregeorgis E et al. Development of a direct alhydrogel formulation immunoassay (DAFIA). J. Immunol. Methods 344(1), 73-78 (2009
-
(2009)
J. Immunol. Methods
, vol.344
, Issue.1
, pp. 73-78
-
-
Zhu, D.1
Huang, S.2
Gebregeorgis, E.3
-
92
-
-
44649198561
-
Lipid A and liposomes containing lipid A as antigens and adjuvants
-
Alving CR, Rao M. Lipid A and liposomes containing lipid A as antigens and adjuvants. Vaccine 26(24), 3036-3045 (2008
-
(2008)
Vaccine
, vol.26
, Issue.24
, pp. 3036-3045
-
-
Alving, C.R.1
Rao, M.2
-
93
-
-
0035747145
-
Liposomal amphotericin B (AmBisome) for fungal infections in immunocompromised adults and children
-
Tollemar J, Klingspor L, Ringdé;n O. Liposomal amphotericin B (AmBisome) for fungal infections in immunocompromised adults and children. Clin. Microbiol. Infect. 7(Suppl. 2), 68-79 (2001
-
(2001)
Clin. Microbiol. Infect
, vol.7
, Issue.SUPPL. 2
, pp. 68-79
-
-
Tollemar, J.1
Klingspor, L.2
Ringdé3
n, O.4
-
94
-
-
0034333241
-
Induction and detection of antibodies to squalene
-
Matyas GR, Wassef NM, Rao M, Alving CR. Induction and detection of antibodies to squalene. J. Immunol. Methods 245(1-2), 1-14 (2000
-
(2000)
J. Immunol. Methods
, vol.245
, Issue.1-2
, pp. 1-14
-
-
Matyas, G.R.1
Wassef, N.M.2
Rao, M.3
Alving, C.R.4
-
95
-
-
0026571596
-
Liposomal malaria vaccine in humans: A safe and potent adjuvant strategy
-
Fries LF, Gordon DM, Richards RL et al. Liposomal malaria vaccine in humans: A safe and potent adjuvant strategy. Proc. Natl Acad. Sci. USA 89(1), 358-362 (1992
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, Issue.1
, pp. 358-362
-
-
Fries, L.F.1
Gordon, D.M.2
Richards, R.L.3
-
96
-
-
0031841564
-
Liposomes containing lipid A serve as an adjuvant for induction of antibody and cytotoxic T-cell responses against RTS,S malaria antigen
-
Richards RL, Rao M, Wassef NM, Glenn GM, Rothwell SW, Alving CR. Liposomes containing lipid A serve as an adjuvant for induction of antibody and cytotoxic T-cell responses against RTS,S malaria antigen. Infect. Immun. 66(6), 2859-2865 (1998
-
(1998)
Infect. Immun
, vol.66
, Issue.6
, pp. 2859-2865
-
-
Richards, R.L.1
Rao, M.2
Wassef, N.M.3
Glenn, G.M.4
Rothwell, S.W.5
Alving, C.R.6
-
97
-
-
84857785011
-
Design considerations for liposomal vaccines: Influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens
-
Watson DS, Endsley AN, Huang L. Design considerations for liposomal vaccines: Influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens. Vaccine 30(13), 2256-2272 (2012
-
(2012)
Vaccine
, vol.30
, Issue.13
, pp. 2256-2272
-
-
Watson, D.S.1
Endsley, A.N.2
Huang, L.3
-
98
-
-
77956630701
-
Synthetic and natural TLR4 agonists as safe and effective vaccine adjuvants
-
Fox CB, Friede M, Reed SG, Ireton GC. Synthetic and natural TLR4 agonists as safe and effective vaccine adjuvants. Subcell. Biochem. 53, 303-321 (2010
-
(2010)
Subcell. Biochem
, vol.53
, pp. 303-321
-
-
Fox, C.B.1
Friede, M.2
Reed, S.G.3
Ireton, G.C.4
-
99
-
-
67349249406
-
MF59 emulsion is an effective delivery system for a synthetic TLR4 agonist E6020
-
Baudner BC, Ronconi V, Casini D et al. MF59 emulsion is an effective delivery system for a synthetic TLR4 agonist (E6020). Pharm. Res. 26(6), 1477-1485 (2009
-
(2009)
Pharm. Res
, vol.26
, Issue.6
, pp. 1477-1485
-
-
Baudner, B.C.1
Ronconi, V.2
Casini, D.3
-
100
-
-
4444291696
-
Pre-clinical evaluation of the malaria vaccine candidate P. Falciparum MSP1(42) formulated with novel adjuvants or with alum
-
Pichyangkul S, Gettayacamin M, Miller RS et al. Pre-clinical evaluation of the malaria vaccine candidate P. falciparum MSP1(42) formulated with novel adjuvants or with alum. Vaccine 22(29-30), 3831-3840 (2004
-
(2004)
Vaccine
, vol.22
, Issue.29-30
, pp. 3831-3840
-
-
Pichyangkul, S.1
Gettayacamin, M.2
Miller, R.S.3
-
101
-
-
77958498224
-
Vaccine adjuvants: Putting innate immunity to work
-
Coffman RL, Sher A, Seder RA. Vaccine adjuvants: Putting innate immunity to work. Immunity 33(4), 492-503 (2010
-
(2010)
Immunity
, vol.33
, Issue.4
, pp. 492-503
-
-
Coffman, R.L.1
Sher, A.2
Seder, R.A.3
-
102
-
-
70349278342
-
Enhanced humoral and Type 1 cellular immune responses with Fluzone adjuvanted with a synthetic TLR4 agonist formulated in an emulsion
-
Baldwin SL, Shaverdian N, Goto Y et al. Enhanced humoral and Type 1 cellular immune responses with Fluzone adjuvanted with a synthetic TLR4 agonist formulated in an emulsion. Vaccine 27(43), 5956-5963 (2009
-
(2009)
Vaccine
, vol.27
, Issue.43
, pp. 5956-5963
-
-
Baldwin, S.L.1
Shaverdian, N.2
Goto, Y.3
-
103
-
-
80053582764
-
Protection of mice from Mycobacterium tuberculosis by ID87/GLA-SE, a novel tuberculosis subunit vaccine candidate
-
Windish HP, Duthie MS, Misquith A et al. Protection of mice from Mycobacterium tuberculosis by ID87/GLA-SE, a novel tuberculosis subunit vaccine candidate. Vaccine 29(44), 7842-7848 (2011
-
(2011)
Vaccine
, vol.29
, Issue.44
, pp. 7842-7848
-
-
Windish, H.P.1
Duthie, M.S.2
Misquith, A.3
-
104
-
-
70350569335
-
Optimized subunit vaccine protects against experimental leishmaniasis
-
Bertholet S, Goto Y, Carter L et al. Optimized subunit vaccine protects against experimental leishmaniasis. Vaccine 27(50), 7036-7045 (2009
-
(2009)
Vaccine
, vol.27
, Issue.50
, pp. 7036-7045
-
-
Bertholet, S.1
Goto, Y.2
Carter, L.3
-
105
-
-
34547870667
-
Leish-111f, a recombinant polyprotein vaccine that protects against visceral leishmaniasis by elicitation of CD4+ T cells
-
Coler RN, Goto Y, Bogatzki L, Raman V, Reed SG. Leish-111f, a recombinant polyprotein vaccine that protects against visceral leishmaniasis by elicitation of CD4+ T cells. Infect. Immun. 75(9), 4648-4654 (2007
-
(2007)
Infect. Immun
, vol.75
, Issue.9
, pp. 4648-4654
-
-
Coler, R.N.1
Goto, Y.2
Bogatzki, L.3
Raman, V.4
Reed, S.G.5
-
106
-
-
0036073291
-
Immunization with a polyprotein vaccine consisting of the T-cell antigens thiolspecific antioxidant Leishmania major stress-inducible protein 1, and Leishmania elongation initiation factor protects against leishmaniasis
-
Coler RN, Skeiky YA, Bernards K et al. Immunization with a polyprotein vaccine consisting of the T-cell antigens thiolspecific antioxidant, Leishmania major stress-inducible protein 1, and Leishmania elongation initiation factor protects against leishmaniasis. Infect. Immun. 70(8), 4215-4225 (2002
-
(2002)
Infect. Immun
, vol.70
, Issue.8
, pp. 4215-4225
-
-
Coler, R.N.1
Skeiky, Y.A.2
Bernards, K.3
-
107
-
-
2942596008
-
Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein
-
Skeiky YA, Alderson MR, Ovendale PJ et al. Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein. J. Immunol. 172(12), 7618-7628 (2004
-
(2004)
J. Immunol
, vol.172
, Issue.12
, pp. 7618-7628
-
-
Skeiky, Y.A.1
Alderson, M.R.2
Ovendale, P.J.3
-
108
-
-
20444503715
-
Tuberculosis vaccine development; from mouse to man
-
Reed S, Lobet Y. Tuberculosis vaccine development; from mouse to man. Microbes Infect. 7(5-6), 922-931 (2005
-
(2005)
Microbes Infect
, vol.7
, Issue.5-6
, pp. 922-931
-
-
Reed, S.1
Lobet, Y.2
-
109
-
-
60549110842
-
Defined tuberculosis vaccine, mtb72f/ as02a, evidence of protection in cynomolgus monkeys
-
Reed SG, Coler RN, Dalemans W et al. Defined tuberculosis vaccine, Mtb72F/ AS02A, evidence of protection in Cynomolgus monkeys. Proc. Natl Acad. Sci. USA 106(7), 2301-2306 (2009
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, Issue.7
, pp. 2301-2306
-
-
Reed, S.G.1
Coler, R.N.2
Dalemans, W.3
-
110
-
-
19444368104
-
Protection of mice and guinea pigs against tuberculosis induced by immunization with a single Mycobacterium tuberculosis recombinant antigen MTB41
-
Skeiky YA, Alderson MR, Ovendale PJ et al. Protection of mice and guinea pigs against tuberculosis induced by immunization with a single Mycobacterium tuberculosis recombinant antigen, MTB41. Vaccine 23(30), 3937-3945 (2005
-
(2005)
Vaccine
, vol.23
, Issue.30
, pp. 3937-3945
-
-
Skeiky, Y.A.1
Alderson, M.R.2
Ovendale, P.J.3
-
111
-
-
70649089205
-
Safety and immunogenicity of a defined vaccine for the prevention of cutaneous leishmaniasis
-
Vé;lez ID, Gilchrist K, Martí;nez S et al. Safety and immunogenicity of a defined vaccine for the prevention of cutaneous leishmaniasis. Vaccine 28(2), 329-337 (2009
-
(2009)
Vaccine
, vol.28
, Issue.2
, pp. 329-337
-
-
Vé1
lez, I.D.2
Gilchrist, K.3
Martí4
nez, S.5
-
112
-
-
68749115366
-
Recent insights into the structure of Toll-like receptors and post-Translational modifications of their associated signalling proteins
-
Carpenter S, O'Neill LA. Recent insights into the structure of Toll-like receptors and post-Translational modifications of their associated signalling proteins. Biochem. J. 422(1), 1-10 (2009
-
(2009)
Biochem. J.
, vol.422
, Issue.1
, pp. 1-10
-
-
Carpenter, S.1
O'Neill, L.A.2
|