Release of IL-12 by dendritic cells activated by TLR ligation is dependent on MyD88 signaling, whereas TRIF signaling is indispensable for TLR synergy

Journal of Leukocyte Biology

Volumn 88, Issue 1, 2010, Pages 189-199

  Krummen, Mathias ^a   Balkow, Sandra ^a   Shen, Limei ^a   Heinz, Stefanie ^a   Loquai, Carmen ^a   Probst, Hans Christian ^a   Grabbe, Stephan ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Cytokines; TH7; TLR ligands; Type I IFNs

Indexed keywords

ALPHA INTERFERON RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; CD40 ANTIGEN; LIPOPOLYSACCHARIDE; MYD88 PROTEIN, MOUSE; TICAM 1 PROTEIN, MOUSE; TICAM-1 PROTEIN, MOUSE; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CPG ISLAND; CYTOKINE PRODUCTION; DENDRITIC CELL; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; C57BL MOUSE; CELL POLARITY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; PHYSIOLOGY;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANTIGENS, CD40; CELL POLARITY; DENDRITIC CELLS; INTERFERON-GAMMA; INTERLEUKIN-12; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; POLY I-C; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 77954679956     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0408228     Document Type: Article

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