Physicochemical characterization and biological activity of synthetic TLR4 agonist formulations

Colloids and Surfaces B: Biointerfaces

Volumn 75, Issue 1, 2010, Pages 123-132

  Anderson, Ryan C ^a   Fox, Christopher B ^a   Dutill, Timothy S ^a   Shaverdian, Narek ^a   Evers, Tara L ^a   Poshusta, Garrett R ^a   Chesko, James ^a   Coler, Rhea N ^a   Friede, Martin ^b   Reed, Steven G ^a   Vedvick, Thomas S ^a  

^a INFECTIOUS DISEASE RESEARCH INSTITUTE   (United States)

^b WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

Oil in water emulsion; Squalene; Synthetic TLR4 agonist; Vaccine adjuvant

Indexed keywords

BIOLOGICAL ACTIVITIES; COMPONENT SUBSTITUTION; IMMUNE RESPONSE; IN-VITRO; LIPID A; OIL DROPLETS; OIL-IN-WATER EMULSION; OIL-IN-WATER EMULSIONS; PHYSICO-CHEMICAL CHARACTERIZATION; SDS-PAGE; SYNTHETIC SOURCES; TOLL-LIKE RECEPTOR 4; ZETA POTENTIAL MEASUREMENTS;

ANIMALS; BIOACTIVITY; DIFFUSERS (OPTICAL); EMULSIONS; SURFACE ACTIVE AGENTS; VACCINES; ZETA POTENTIAL;

EMULSIFICATION;

IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; MIGLYOL; PHOSPHORYL LIPID A; POLOXAMER; POLYSORBATE 80; SQUALENE;

ANIMAL CELL; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG MECHANISM; DRUG POTENCY; EMULSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; ZETA POTENTIAL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BIOLOGICAL ASSAY; CELL LINE; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EMULSIONS; ENDPOINT DETERMINATION; HEAT-SHOCK PROTEINS; IMMUNOGLOBULIN G; INJECTIONS; INTERFERON-GAMMA; LIPID A; MICE; PARTICLE SIZE; PHYSICOCHEMICAL PHENOMENA; PROTOZOAN PROTEINS; SURFACE PROPERTIES; TOLL-LIKE RECEPTOR 4;

ANIMALIA;

EID: 70449627069     PISSN: 09277765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2009.08.022     Document Type: Article

References (46)

1. Hem S.L., and HogenEsch H. In: Singh M. (Ed). Vaccine Adjuvants and Delivery Systems (2007), John Wiley & Sons, Hoboken, NJ 81-114
2. Li H., Nookala S., and Re F. J. Immunol. 178 (2007) 5271
3. Deville S., Pooter A., Aucouturier J., Laine-Prade V., Cote M., Boireau P., and Vallee I. Vet. Parasitol. 132 (2005) 75
4. O'Hagan D.T., and Singh M. In: Singh M. (Ed). Vaccine Adjuvants and Delivery Systems (2007), John Wiley & Sons, Hoboken, NJ 115-129
5. Del Giudice G., Fragapane E., Bugarini R., Hora M., Henriksson T., Palla E., O'Hagan D., Donnelly J., Rappuoli R., and Podda A. Clin. Vaccine Immunol. 13 (2006) 1010
6. Cataldo D., and Van Nest G. Vaccine 15 (1997) 1710
7. Bandyopadhyay P., and Johnson M. Colloids Surf. B: Biointerfaces 58 (2007) 68
8. Abramson M.B., Katzman R., Wilson C.E., and Gregor H.P. J. Biol. Chem. 239 (1964) 4066
9. Brandenburg K., and Wiese A. Curr. Top. Med. Chem. 4 (2004) 1127
10. Simberg D., Weisman S., Talmon Y., and Barenholz Y. Crit. Rev. Ther. Drug Carr. Syst. 21 (2004) 257
11. Campos-Neto A., Porrozzi R., Greeson K., Coler R.N., Webb J.R., Seiky Y.A., Reed S.G., and Grimaldi Jr. G. Infect. Immun. 69 (2001) 4103
12. Fox C.B., Anderson R.C., Dutill T.S., Goto Y., Reed S.G., and Vedvick T. Colloids Surf. B: Biointerfaces 65 (2008) 98
13. Schulte S., Sukhova G.K., and Libby P. Am. J. Pathol. 172 (2008) 1500
14. Baldwin S.L., Bertholet S., Kahn M., Zharkikh I., Ireton G.C., Vedvick T.S., Reed S.G., and Coler R.N. Vaccine 27 (2009) 3063
15. Zwiorek K., Bourquin C., Battiany J., Winter G., Endres S., Hartmann G., and Coester C. Pharm. Res. 25 (2008) 551
16. Roth J., Hibbard B., Frank D., Kesl L., and Robb E. Vet. Ther.: Res. Appl. Vet. Med. 3 (2002) 347
17. Baldridge J.R., and Crane R.T. Methods 19 (1999) 103
18. Vandepapeliere P., Rehermann B., Koutsoukos M., Moris P., Garcon N., Wettendorff M., and Leroux-Roels G. Vaccine 23 (2005) 2591
19. DeStefano F., and Thompson W.W. Expert Rev. Vaccines 3 (2004) 19
20. Jiang Z., Budzynski W., Qiu D., Yalamati D., and Koganty R. Carbohydr. Res. 342 (2007) 784
21. Stover A., Da Silva Correia J., Evans J., Cluff C., Elliott M., Jeffery E., Johnson D.A., Lacy M., Baldridge J.R., Probst P., Ulevitch R., Pershing D., and Hershberg R. J. Biol. Chem. 279 (2004) 4440
22. Baudner B.C., Ronconi V., Casini D., Tortoli M., Kazzaz J., Singh M., Hawkins L.D., Wack A., and O'Hagan D.T. Pharm. Res. 26 (2009) 1477
23. Morefield G.L., Hawkins L.D., Ishizaka S.T., Kissner T.L., and Ulrich R.G. Clin. Vaccine Immunol. 14 (2007) 1499
24. O'Hagan D.T., and Valiante N.M. Nat. Rev. Drug Discov. 2 (2003) 727
25. Dupuis M., Denis-Mize K., LaBarbara A., Peters W., Charo I.F., McDonald D.M., and Ott G. Eur. J. Immunol. 31 (2001) 2910
26. Foged C., Brodin B., Frokjaer S., and Sundblad A. Int. J. Pharm. 298 (2005) 315
27. Floyd A.G. Pharm. Sci. Technol. Today 2 (1999) 134
28. Norden T.P., Siekmann B., Lundquist S., and Malmsten M. Eur. J. Pharm. Sci. 13 (2001) 393
29. Liu F., and Liu D. Pharm. Res. 12 (1995) 1060
30. McClements D.J. Crit. Rev. Food Sci. Nutr. 47 (2007) 611
31. McClements D.J., and Decker E.A. J. Food Sci. 65 (2000) 1270
32. Mueller M., Lindner B., Kusumoto S., Fukase K., Schromm A.B., and Seydel U. J. Biol. Chem. 279 (2004) 26307
33. Chiang C., Chen F., Hong J., Jiang P., Huang H., Wang C., and McBride W. Int. Immunol. 20 (2008) 215
34. Krutzik P., Hale M., and Nolan G. J. Immunol. 175 (2005) 2366
35. Mosca F., Tritto E., Muzzi A., Monaci E., Bagnoli F., Iavarone C., O'Hagan D., Rappuoli R., and De Gregorio E. Proc. Natl. Acad. Sci. 105 (2008) 10501
36. Ott G., Barchfeld G.L., Chernoff D., Radhakrishnan R., van Hoogevest P., and Van Nest G. In: Powell M.F., and Newman M.J. (Eds). Vaccine Design: The Subunit and Adjuvant Approach (1995), Plenum Press, New York 277-296
37. Pruett S., Fan R., Zheng Q., and Schwab C. Alcohol 37 (2005) 1
38. Monick M., Powers L., Butler N., Yarovinsky T., and Hunninghake G. Am. J. Physiol.: Lung Cell. Mol. Physiol. 283 (2002) L390
39. Hirano S., and Kanno S. Immunology 97 (1999) 414
40. Hunter R., Strickland F., and Kezdy F. J. Immunol. 127 (1981) 1244
41. Hunter R.L., and Bennett B. J. Immunol. 133 (1984) 3167
42. Jansen T., Hofmans M.P.M., Theelen M.J.G., Manders F., and Schijns V.E.J.C. Vaccine 24 (2006) 5400
43. N. Garcon, P. Momin, Oil in Water Vaccine Compositions, WO/1998/056414 (1998).
44. Wang Y.J., Wu C.A., and Morrow W.J. Vaccine 22 (2004) 1524
45. Chung H., Kim T.W., Kwon M., Kwon I.C., and Jeong S.Y. J. Control. Rel. 71 (2001) 339
46. Kan P., Chen Z.B., Lee C.J., and Chu I.M. J. Control. Rel. 58 (1999) 271