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Volumn 86, Issue 1027, 2013, Pages

Deoxyribonucleic acid damage-associated biomarkers of ionising radiation: Current status and future relevance for radiology and radiotherapy

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DNA; EFAPROXIRAL; FLUOROURACIL; HISTONE H2AX; RNA; BIOLOGICAL MARKER;

EID: 84880016567     PISSN: 00071285     EISSN: None     Source Type: Journal    
DOI: 10.1259/bjr.20130173     Document Type: Review
Times cited : (18)

References (117)
  • 8
    • 0034069125 scopus 로고    scopus 로고
    • Cytogenetic monitoring of hospital workers occupationally exposed to ionizing radiation using the micronucleus centromere assay
    • Thierens H, Vral A, Morthier R, Aousalah B, De Riddler L. Cytogenetic monitoring of hospital workers occupationally exposed to ionizing radiation using the micronucleus centromere assay. Mutagenesis 2000;15:245-9. (Pubitemid 30312715)
    • (2000) Mutagenesis , vol.15 , Issue.3 , pp. 245-249
    • Thierens, H.1    Vral, A.2    Morthier, R.3    Aousalah, B.4    De Ridder, L.5
  • 9
    • 0037340936 scopus 로고    scopus 로고
    • Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay
    • Thomas P, Umegaki K, Fenech M. Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay. Mutagenesis 2003;18:187 -94.
    • (2003) Mutagenesis , vol.18 , pp. 187-194
    • Thomas, P.1    Umegaki, K.2    Fenech, M.3
  • 10
    • 0004155592 scopus 로고    scopus 로고
    • International Atomic Energy Agency. Vienna, Austria: International Atomic Energy Agency
    • International Atomic Energy Agency. The radiological accident in Istanbul. Vienna, Austria: International Atomic Energy Agency; 2000.
    • (2000) The Radiological Accident in Istanbul
  • 11
    • 79951670718 scopus 로고    scopus 로고
    • Comparison of the micronucleus and chromosome aberration techniques for the documentation of cytogenetic damage in radiochemotherapy-treated patients with rectal cancer
    • Wolff HA, Hennies S, Herrmann M, Rave-Fränk M, Eickelmann D, Virsik P, et al. Comparison of the micronucleus and chromosome aberration techniques for the documentation of cytogenetic damage in radiochemotherapy-treated patients with rectal cancer. Strahlenther Onkol 2011;187:52-8.
    • (2011) Strahlenther Onkol , vol.187 , pp. 52-58
    • Wolff, H.A.1    Hennies, S.2    Herrmann, M.3    Rave-Fränk, M.4    Eickelmann, D.5    Virsik, P.6
  • 12
    • 75149176761 scopus 로고    scopus 로고
    • Automated micronucleus (MN) scoring for population triage in case of large scale radiation events
    • doi: 10.3109/09553000903264481
    • Willems P, August L, Slabbert J, Romm H, Oestreicher U, Thierens H, et al. Automated micronucleus (MN) scoring for population triage in case of large scale radiation events. Int J Radiat Biol 2010;86:2-11. doi: 10.3109/09553000903264481.
    • (2010) Int J Radiat Biol , vol.86 , pp. 2-11
    • Willems, P.1    August, L.2    Slabbert, J.3    Romm, H.4    Oestreicher, U.5    Thierens, H.6
  • 13
    • 78650640476 scopus 로고    scopus 로고
    • Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and biodosimetry of genotoxin exposure
    • doi: 10.1093/mutage/geq057
    • Rossnerova A, Spatova M, Schunck C, Sram RJ. Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and biodosimetry of genotoxin exposure. Mutagenesis 2011;26:169-75. doi: 10.1093/mutage/geq057.
    • (2011) Mutagenesis , vol.26 , pp. 169-175
    • Rossnerova, A.1    Spatova, M.2    Schunck, C.3    Sram, R.J.4
  • 14
    • 75649120068 scopus 로고    scopus 로고
    • The lymphocyte cytokinesisblock micronucleus cytome assay and its application in radiation biodosimetry
    • doi: 10.1097/HP.0b013e3181b85044
    • Fenech M. The lymphocyte cytokinesisblock micronucleus cytome assay and its application in radiation biodosimetry. Health Phys 2010;98:234-43. doi: 10.1097/HP.0b013e3181b85044.
    • (2010) Health Phys , vol.98 , pp. 234-243
    • Fenech, M.1
  • 15
    • 0014959463 scopus 로고
    • Mammalian cell fusion: Induction of premature chromosome condensation in interphase nuclei
    • Johnson RT, Rao PN. Mammalian cell fusion: induction of premature chromosome condensation in interphase nuclei. Nature 1970;226:717-22.
    • (1970) Nature , vol.226 , pp. 717-722
    • Johnson, R.T.1    Rao, P.N.2
  • 16
    • 0021245702 scopus 로고
    • The use of peripheral blood mononuclear cell prematurely condensed chromosomes for biological dosimetry
    • Pantelias GE, Maillie HD. The use of peripheral blood mononuclear cell prematurely condensed chromosomes for biological dosimetry. Radiat Res 1984;99:140-50. (Pubitemid 14095140)
    • (1984) Radiation Research , vol.99 , Issue.1 , pp. 140-150
    • Pantelias, G.E.1    Maillie, H.D.2
  • 17
    • 34548017603 scopus 로고    scopus 로고
    • The use of premature chromosome condensation to study the influence of environmental factors on human genetic material in interphase cells
    • DOI 10.1100/tsw.2006.210
    • Hatzi VI, Terzoudi GI, Paraskevopoulou C, Makropoulos V, Matthopoulos DP, Pantelias GE. The use of premature chromosome condensation to study the influence of environmental factors on human genetic material in interphase cells. Scientific-World Journal 2006;6:1174-90. doi: 10.1100/tsw.2006.210. (Pubitemid 47279338)
    • (2006) TheScientificWorldJournal , vol.6 , pp. 1174-1190
    • Hatzi, V.I.1    Terzoudi, G.I.2    Paraskevopoulou, C.3    Makropoulos, V.4    Matthopoulos, D.P.5    Pantelias, G.E.6
  • 18
    • 16644381100 scopus 로고    scopus 로고
    • Premature chromosome condensation in human resting peripheral blood lymphocytes for chromosome aberration analysis using specific whole-chromosome DNA hybridisation probes
    • Prasanna PG, Blakely WF. Premature chromosome condensation in human resting peripheral blood lymphocytes for chromosome aberration analysis using specific whole-chromosome DNA hybridisation probes. Methods Mol Biol 2005;291:49-57.
    • (2005) Methods Mol Biol , vol.291 , pp. 49-57
    • Prasanna, P.G.1    Blakely, W.F.2
  • 19
    • 0035468436 scopus 로고    scopus 로고
    • Cytogenetical dose estimation for 3 severely exposed patients in the JCO criticality accident in Tokai-mura
    • Hayata I, Kanda R, Minamihisamatsu M, Furukawa M, Sasaki MS. Cytogenetical dose estimation for 3 severely exposed patients in the JCO criticality accident in Tokai-mura. J Radiat Res 2001;42:S149-55.
    • (2001) J Radiat Res , vol.42
    • Hayata, I.1    Kanda, R.2    Minamihisamatsu, M.3    Furukawa, M.4    Sasaki, M.S.5
  • 20
    • 73349087183 scopus 로고    scopus 로고
    • Premature chromosome condensation (PCC) assay for dose assessment in mass casualty accidents
    • doi: 10.1667/RR1843.1
    • Lindholm C, Stricklin D, Jaworska A, Koivistoinen A, Paile W, Arvidsson E, et al. Premature chromosome condensation (PCC) assay for dose assessment in mass casualty accidents. Radiat Res 2010;173:71-8. doi: 10.1667/RR1843.1.
    • (2010) Radiat Res , vol.173 , pp. 71-78
    • Lindholm, C.1    Stricklin, D.2    Jaworska, A.3    Koivistoinen, A.4    Paile, W.5    Arvidsson, E.6
  • 21
    • 0031829416 scopus 로고    scopus 로고
    • Detection of total- and partial-body irradiation in a monkey model: A comparative study of chromosomal aberration, micronucleus and premature chromosome condensation assays
    • DOI 10.1080/095530098141582
    • Darroudi F, Natarajan AT, Bentvelzen PA, Heidt PJ, Van Rotterdam A, Zoetelief J. Detection of total- and partial-body irradiation in a monkey model: a comparative study of chromosomal aberration, micronucleus and premature chromosome condensation assays. Int J Radiat Biol 1998;74:207-15. (Pubitemid 28372547)
    • (1998) International Journal of Radiation Biology , vol.74 , Issue.2 , pp. 207-215
    • Darroudi, F.1    Natarajan, A.T.2    Bentvelzen, P.A.J.3    Heidt, P.J.4    Van Rotterdam, A.5    Zoetelief, J.6    Broerse, J.J.7
  • 22
    • 4644308587 scopus 로고    scopus 로고
    • Long-term persistence of translocations in stable lymphocytes from victims of a radiological accident
    • DOI 10.1080/09553000412331283498
    • Lindholm C, Edwards A. Long-term persistence of translocations in stable lymphocytes from victims of a radiological accident. Int J Radiat Biol 2004;80:559-66. doi: 10.1080/09553000412331283498. (Pubitemid 39287041)
    • (2004) International Journal of Radiation Biology , vol.80 , Issue.8 , pp. 559-566
    • Lindholm, C.1    Edwards, A.2
  • 23
    • 0742271722 scopus 로고    scopus 로고
    • Persistence of translocation frequencies in blood lymphocytes following radiotherapy: Implications for retrospective radiation biodosimetry
    • DOI 10.1088/0952-4746/23/4/005, PII S095247460369765X
    • Tawn EJ, Whitehouse CA. Persistence of translocation frequencies in blood lymphocytes following radiotherapy: implications for retrospective radiation biodosimetry. J Radiol Prot 2003;23:423-30. (Pubitemid 38145610)
    • (2003) Journal of Radiological Protection , vol.23 , Issue.4 , pp. 423-430
    • Tawn, E.J.1    Whitehouse, C.A.2
  • 24
    • 0027183127 scopus 로고
    • Radiation-induced chromosome aberrations analysed by two-color fluorescence in situ hybridization with composite whole chromosome-specific DNA probes and a pancentromeric DNA probe
    • Bauchinger M, Schmid E, Zitzelsberger H, Braselmann H, Nahrstedt U. Radiation-induced chromosome aberrations analysed by two-color fluorescence in situ hybridization with composite whole chromosomespecific DNA probes and a pancentromeric DNA probe. Int J Radiat Biol 1993;64:179-84. (Pubitemid 23266758)
    • (1993) International Journal of Radiation Biology , vol.64 , Issue.2 , pp. 179-184
    • Bauchinger, M.1    Schmid, E.2    Zitzelsberger, H.3    Braselmann, H.4    Nahrstedt, U.5
  • 25
    • 0026755856 scopus 로고
    • Rapid translocation frequency analysis in humans decades after exposure to ionising radiation
    • Lucas JN, Awa A, Straume T, Poggensee M, Kodama Y, Nakano M, et al. Rapid translocation frequency analysis in humans decades after exposure to ionising radiation. Int J Radiat Biol 1992;62:53-63.
    • (1992) Int J Radiat Biol , vol.62 , pp. 53-63
    • Lucas, J.N.1    Awa, A.2    Straume, T.3    Poggensee, M.4    Kodama, Y.5    Nakano, M.6
  • 27
    • 43049090758 scopus 로고    scopus 로고
    • International study of factors affecting human chromosome translocations
    • doi: 10.1016/j.mrgentox.2008.01.005.
    • Sigurdson AJ, Ha M, Hauptmann M, Bhatti P, Sram RJ, Beskid O, et al. International study of factors affecting human chromosome translocations. Mutat Res 2008;652:112-21. doi: 10.1016/j.mrgentox.2008.01.005.
    • (2008) Mutat Res , vol.652 , pp. 112-121
    • Sigurdson, A.J.1    Ha, M.2    Hauptmann, M.3    Bhatti, P.4    Sram, R.J.5    Beskid, O.6
  • 28
    • 79955461690 scopus 로고    scopus 로고
    • Estimating the lowest detectable dose of ionising radiation by FISH whole-chromosome painting
    • doi: 10.1667/RR2506.1.
    • Tucker JD, Luckinbill LS. Estimating the lowest detectable dose of ionising radiation by FISH whole-chromosome painting. Radiat Res 2011;175:631-7. doi: 10.1667/RR2506.1.
    • (2011) Radiat Res , vol.175 , pp. 631-637
    • Tucker, J.D.1    Luckinbill, L.S.2
  • 29
    • 78649332647 scopus 로고    scopus 로고
    • Diagnostic X-ray examinations and increased chromosome translocations: Evidence from three studies
    • doi: 10.1007/s00411-010-0307-z.
    • Bhatti P, Yong LC, Doody MM, Preston DL, Kampa DM, Ramsey MJ, et al. Diagnostic X-ray examinations and increased chromosome translocations: evidence from three studies. Radiat Environ Biophys 2010;49:685-92. doi: 10.1007/s00411-010-0307-z.
    • (2010) Radiat Environ Biophys , vol.49 , pp. 685-692
    • Bhatti, P.1    Yong, L.C.2    Doody, M.M.3    Preston, D.L.4    Kampa, D.M.5    Ramsey, M.J.6
  • 32
    • 33845606709 scopus 로고    scopus 로고
    • Leukocyte DNA damage after multi-detector row CT: A quantitative biomarker of low-level radiation exposure
    • DOI 10.1148/radiol.2421060171
    • Rothkamm K, Balroop S, Shekdar J, Fernie P, Goh V. Leukocyte DNA damage after multi-detector row CT: a quantitative biomarker of low-level radiation exposure. Radiology 2007;242:244-51. doi: 10.1148/radiol.2421060171. (Pubitemid 44956030)
    • (2007) Radiology , vol.242 , Issue.1 , pp. 244-251
    • Rothkamm, K.1    Balroop, S.2    Shekhdar, J.3    Fernie, P.4    Goh, V.5
  • 33
    • 34548359085 scopus 로고    scopus 로고
    • Gamma-H2AX foci formation in peripheral blood lymphocytes of tumor patients after local radiotherapy to different sites of the body: Dependence on the dose-distribution, irradiated site and time from start of treatment
    • DOI 10.1080/09553000701596118, PII 781563311
    • Sak A, Grehl S, Erichsen P, Engelhard M, Grannass A, Levegrün S, et al. Gamma-H2AX foci formation in peripheral blood lymphocytes of tumour patients after local radiotherapy to different sites of the body: dependence on the dose-distribution, irradiated site and time from start of treatment. Int J Radiat Biol 2007;83:639-52. (Pubitemid 47345867)
    • (2007) International Journal of Radiation Biology , vol.83 , Issue.10 , pp. 639-652
    • Sak, A.1    Grehl, S.2    Erichsen, P.3    Engelhard, M.4    Grannass, A.5    Levegrun, S.6    Pottgen, C.7    Groneberg, M.8    Stuschke, M.9
  • 34
    • 80053109692 scopus 로고    scopus 로고
    • Gamma-H2AX-based dose estimation for whole and partial body radiation exposure
    • doi: 10.1371/journal.pone.0025113
    • Horn S, Bernard S, Rothkamm K. Gamma-H2AX-based dose estimation for whole and partial body radiation exposure. PLoS One 2011;6:e25113. doi: 10.1371/journal.pone.0025113.
    • (2011) PLoS One , vol.6
    • Horn, S.1    Bernard, S.2    Rothkamm, K.3
  • 35
    • 79952158787 scopus 로고    scopus 로고
    • Adapting the g-H2AX for automated processing in human lymphocytes. 1. Technological aspects
    • doi: 10.1667/RR2125.1
    • Turner HC, Brenner DJ, Chen Y, Bertucci A, Zhang J, Wang H, et al. Adapting the g-H2AX for automated processing in human lymphocytes. 1. Technological aspects. Radiat Res 2011;175:282-90. doi: 10.1667/RR2125.1.
    • (2011) Radiat Res , vol.175 , pp. 282-290
    • Turner, H.C.1    Brenner, D.J.2    Chen, Y.3    Bertucci, A.4    Zhang, J.5    Wang, H.6
  • 36
    • 80052958787 scopus 로고    scopus 로고
    • A portable microfluidic fluorescence spectrometer device for H2AX-based biological dosimetry
    • doi: 10.1016/j.radmeas.2011.02.004
    • Pope IA, Barber PR, Horn S, Ainsbury E, Rothkamm K, Vojnovic B. A portable microfluidic fluorescence spectrometer device for H2AX-based biological dosimetry. Radiation Measurements 2011;46:907-11. doi: 10.1016/j.radmeas.2011. 02.004.
    • (2011) Radiation Measurements , vol.46 , pp. 907-911
    • Pope, I.A.1    Barber, P.R.2    Horn, S.3    Ainsbury, E.4    Rothkamm, K.5    Vojnovic, B.6
  • 37
    • 80052930413 scopus 로고    scopus 로고
    • Review of retrospective dosimetry techniques for external ionising radiation exposures
    • doi: 10.1093/rpd/ncq499
    • Ainsbury EA, Bakhanova E, Barquinero JF, Brai M, Chumak V, Correcher V, et al. Review of retrospective dosimetry techniques for external ionising radiation exposures. Radiat Prot Dosimetry 2011;147:573-92. doi: 10.1093/rpd/ncq499.
    • (2011) Radiat Prot Dosimetry , vol.147 , pp. 573-592
    • Ainsbury, E.A.1    Bakhanova, E.2    Barquinero, J.F.3    Brai, M.4    Chumak, V.5    Correcher, V.6
  • 38
    • 79551637587 scopus 로고    scopus 로고
    • Gene expression following ionising radiation: Identification of biomarkers for dose estimation and prediction of individual response
    • doi: 10.3109/09553002.2010.519424
    • Kabacik S, Mackay A, Tamber N, Manning G, Finnon P, Paillier F, et al. Gene expression following ionising radiation: identification of biomarkers for dose estimation and prediction of individual response. Int J Radiat Biol 2011;87:115-29. doi: 10.3109/09553002.2010.519424.
    • (2011) Int J Radiat Biol , vol.87 , pp. 115-129
    • Kabacik, S.1    Mackay, A.2    Tamber, N.3    Manning, G.4    Finnon, P.5    Paillier, F.6
  • 39
    • 0032878399 scopus 로고    scopus 로고
    • Induction of stress genes by low doses of gamma rays
    • DOI 10.2307/3580321
    • Amundson SA, Do KT, Fornace AJ Jr. Induction of stress genes by low doses of gamma rays. Radiat Res 1999;152:225-31. (Pubitemid 29413657)
    • (1999) Radiation Research , vol.152 , Issue.3 , pp. 225-231
    • Amundson, S.A.1    Do, K.T.2    Fornace Jr., A.J.3
  • 40
    • 44849110695 scopus 로고    scopus 로고
    • Gene expression signatures of radiation response are specific, durable and accurate in mice and humans
    • doi: 10.1371/journal.pone.0001912
    • Meadows SK, Dressman HK, Muramoto GG, Himburg H, Salter A, Wei Z, et al. Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. PLoS One 2008;3: e1912. doi: 10.1371/journal.pone. 0001912.
    • (2008) PLoS One , vol.3
    • Meadows, S.K.1    Dressman, H.K.2    Muramoto, G.G.3    Himburg, H.4    Salter, A.5    Wei, Z.6
  • 41
    • 18344404653 scopus 로고    scopus 로고
    • Long-term global gene expression patterns in irradiated human lymphocytes
    • doi: 10.1093/carcin/bgg134
    • Fält S, Holmberg K, Lambert B, Wennborg A. Long-term global gene expression patterns in irradiated human lymphocytes. Carcinogenesis 2003;24: 1837 - 45. doi: 10.1093/carcin/bgg134.
    • (2003) Carcinogenesis , vol.24 , pp. 1837-1845
    • Fält, S.1    Holmberg, K.2    Lambert, B.3    Wennborg, A.4
  • 42
    • 70350738787 scopus 로고    scopus 로고
    • Gene expression changes in medical workers exposed to radiation
    • doi: 10.1667/RR1545.1
    • Morandi E, Severini C, Quercioli D, Perdichizzi S, Mascolo M, Horn W, et al. Gene expression changes in medical workers exposed to radiation. Radiat Res 2009; 172:500-8. doi: 10.1667/RR1545.1.
    • (2009) Radiat Res , vol.172 , pp. 500-508
    • Morandi, E.1    Severini, C.2    Quercioli, D.3    Perdichizzi, S.4    Mascolo, M.5    Horn, W.6
  • 43
    • 34247498181 scopus 로고    scopus 로고
    • Gene expression signatures that predict radiation exposure in mice and humans
    • doi: 10.1371/journal.pmed.0040106
    • Dressman HK, Muramoto GG, Chao NJ, Meadows S, Marshall D, Ginsburg GS, et al. Gene expression signatures that predict radiation exposure in mice and humans. PLoS Med 2007;4:e106. doi: 10.1371/journal.pmed.0040106.
    • (2007) PLoS Med , vol.4
    • Dressman, H.K.1    Muramoto, G.G.2    Chao, N.J.3    Meadows, S.4    Marshall, D.5    Ginsburg, G.S.6
  • 46
    • 79953667089 scopus 로고    scopus 로고
    • A minimally invasive assay for individual assessment of the ATM/CHEK2/p53 pathway activity
    • Kabacik S, Ortega-Molina A, Efeyan A, Finnon P, Bouffler S, Serrano M, et al. A minimally invasive assay for individual assessment of the ATM/CHEK2/p53 pathway activity. Cell Cycle 2011;10:1152-61.
    • (2011) Cell Cycle , vol.10 , pp. 1152-1161
    • Kabacik, S.1    Ortega-Molina, A.2    Efeyan, A.3    Finnon, P.4    Bouffler, S.5    Serrano, M.6
  • 47
    • 0041441131 scopus 로고    scopus 로고
    • Development and assessment of a quantitative reverse transcription-PCR assay for simultaneous measurement of four amplicons
    • DOI 10.1373/49.9.1467
    • Grace MB, McLeland CB, Gagliardi SJ, Smith JM, Jackson WE 3rd, Blakely WF. Development and assessment of a quantitative reverse transcription-PCR assay for simultaneous measurement of four amplicons. Clin Chem 2003;49:1467-75. (Pubitemid 37011734)
    • (2003) Clinical Chemistry , vol.49 , Issue.9 , pp. 1467-1475
    • Grace, M.B.1    McLeland, C.B.2    Gagliardi, S.J.3    Smith, J.M.4    Jackson III, W.E.5    Blakely, W.F.6
  • 49
    • 84878652790 scopus 로고    scopus 로고
    • High and low dose responses of transcriptional biomarkers in ex vivo X-irradiated human blood
    • Feb Epub ahead of print. doi: 10.3109/09553002.2013.769694
    • Manning G, Kabacik S, Finnon P, Bouffler S, Badie C. High and low dose responses of transcriptional biomarkers in ex vivo X-irradiated human blood. Int J Radiat Biol Feb 2013. Epub ahead of print. doi: 10.3109/09553002.2013.769694.
    • (2013) Int J Radiat Biol
    • Manning, G.1    Kabacik, S.2    Finnon, P.3    Bouffler, S.4    Badie, C.5
  • 50
    • 75649110801 scopus 로고    scopus 로고
    • Biodosimetry on small blood volume using gene expression assay
    • doi: 10.1097/01.HP.0000346706.44253.5c
    • Brengues M, Paap B, Bittner M, Amundson S, Seligmann B, Korn R, et al. Biodosimetry on small blood volume using gene expression assay. Health Phys 2010;98:179-85. doi: 10.1097/01.HP.0000346706.44253.5c.
    • (2010) Health Phys , vol.98 , pp. 179-185
    • Brengues, M.1    Paap, B.2    Bittner, M.3    Amundson, S.4    Seligmann, B.5    Korn, R.6
  • 51
    • 77955375162 scopus 로고    scopus 로고
    • Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles
    • 2010. doi: 10.1371/journal.pone.0011535
    • Meadows SK, Dressman HK, Daher P, Himburg H, Russell JL, Doan P, et al. Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles. PLoS One 2010;5: e11535, 2010. doi: 10.1371/journal.pone. 0011535.
    • (2010) PLoS One , vol.5
    • Meadows, S.K.1    Dressman, H.K.2    Daher, P.3    Himburg, H.4    Russell, J.L.5    Doan, P.6
  • 52
    • 51649099542 scopus 로고    scopus 로고
    • Broad modulation of gene expression in CD4+ lymphocyte subpopulations in response to low doses of ionising radiation
    • doi: 10.1667/RR1147.1
    • Gruel G, Voisin P, Vaurijoux A, Roch-Lefevre S, Grégoire E, Maltere P, et al. Broad modulation of gene expression in CD4+ lymphocyte subpopulations in response to low doses of ionising radiation. Radiat Res 2008;170:335-44. doi: 10.1667/RR1147.1.
    • (2008) Radiat Res , vol.170 , pp. 335-344
    • Gruel, G.1    Voisin, P.2    Vaurijoux, A.3    Roch-Lefevre, S.4    Grégoire, E.5    Maltere, P.6
  • 54
    • 77649233414 scopus 로고    scopus 로고
    • Why the need for QPCR publication guidelines? The case for MIQE
    • doi: 10.1016/j.ymeth.2009.12.006
    • Bustin SA. Why the need for QPCR publication guidelines? The case for MIQE. Methods 2010;50:217-26. doi: 10.1016/j.ymeth.2009.12.006.
    • (2010) Methods , vol.50 , pp. 217-226
    • Bustin, S.A.1
  • 55
    • 64149097786 scopus 로고    scopus 로고
    • The MIQE guidelines: Minimum information for publication of quantitative real-time PCR experiments
    • doi: 10.1373/clinchem.2008.112797
    • Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M, et al. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 2009;55:611-22. doi: 10.1373/clinchem.2008. 112797.
    • (2009) Clin Chem , vol.55 , pp. 611-622
    • Bustin, S.A.1    Benes, V.2    Garson, J.A.3    Hellemans, J.4    Huggett, J.5    Kubista, M.6
  • 58
    • 36549007486 scopus 로고    scopus 로고
    • Computed tomography - An increasing source of radiation exposure
    • DOI 10.1056/NEJMra072149
    • Brenner DJ, Hall EJ. Computed tomography - an increasing source of radiation exposure. N Engl J Med 2007;357:2277-84. (Pubitemid 350190758)
    • (2007) New England Journal of Medicine , vol.357 , Issue.22 , pp. 2277-2284
    • Brenner, D.J.1    Hall, E.J.2
  • 61
    • 84864776903 scopus 로고    scopus 로고
    • Radiation exposure from CTscans in childhood and subsequent risk of leukaemia and brain tumours: A retrospective cohort study
    • Pearce MS, Salotti JA, Little MP, McHugh K, Lee C, Kim KP, et al. Radiation exposure from CTscans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study. Lancet 2012;380:499-505.
    • (2012) Lancet , vol.380 , pp. 499-505
    • Pearce, M.S.1    Salotti, J.A.2    Little, M.P.3    McHugh, K.4    Lee, C.5    Kim, K.P.6
  • 62
    • 72449153474 scopus 로고    scopus 로고
    • Gamma-H2AX foci as a biomarker for patient X-ray exposure in pediatric cardiac catheterization: Are we understanding radiation risks?
    • Beels L, Bacher K, De Wolf D, Werbrouck J, Thierens H. Gamma-H2AX foci as a biomarker for patient X-ray exposure in pediatric cardiac catheterization: are we understanding radiation risks? Circulation 2009;10:1903-9.
    • (2009) Circulation , vol.10 , pp. 1903-1909
    • Beels, L.1    Bacher, K.2    De Wolf, D.3    Werbrouck, J.4    Thierens, H.5
  • 64
    • 70449086291 scopus 로고    scopus 로고
    • The influence of x-ray contrast agents in computed tomography on the induction of dicentrics and gamma-H2AX foci in lymphocytes of human blood samples
    • doi: 10.1088/0031-9155/54/20/001
    • Jost G, Golfier S, Pietsch H, Lengsfeld P, Voth M, Schmid TE, et al. The influence of x-ray contrast agents in computed tomography on the induction of dicentrics and gamma-H2AX foci in lymphocytes of human blood samples. Phys Med Biol 2009;54: 6029-39. doi: 10.1088/0031-9155/54/20/001.
    • (2009) Phys Med Biol , vol.54 , pp. 6029-6039
    • Jost, G.1    Golfier, S.2    Pietsch, H.3    Lengsfeld, P.4    Voth, M.5    Schmid, T.E.6
  • 65
    • 0036147261 scopus 로고    scopus 로고
    • M for various end points
    • Frankenberg D, Kelnhofer K, Bär K, Frankenberg-Schwager M. Enhanced neoplastic transformation by mammography X rays relative to 200 kVp X rays: indication for a strong dependence on photon energy of the RBE(M) for various end points. Radiat Res 2002;157:99-105. (Pubitemid 34073393)
    • (2002) Radiation Research , vol.157 , Issue.1 , pp. 99-105
    • Frankenberg, D.1    Kelnhofer, K.2    Bar, K.3    Frankenberg-Schwager, M.4
  • 66
    • 0344303535 scopus 로고    scopus 로고
    • Re-evaluation of the RBE of 29 kV x-rays (mammography x-rays) relative to 220 kV x-rays using neoplastic transformation of human CGL1-hybrid cells
    • DOI 10.1007/s00411-003-0210-y
    • Göggelmann W, Jacobsen C, Panzer W, Walsh L, Roos H, Schmid E. Re-evaluation of the RBE of 29 kV x-rays (mammography x-rays) relative to 220 kV x-rays using neoplastic transformation of human CGL1-hybrid cells. Radiat Environ Biophys 2003;42:175-82. (Pubitemid 37518061)
    • (2003) Radiation and Environmental Biophysics , vol.42 , Issue.3 , pp. 175-182
    • Goggelmann, W.1    Jacobsen, C.2    Panzer, W.3    Walsh, L.4    Roos, H.5    Schmid, E.6
  • 68
    • 80053906135 scopus 로고    scopus 로고
    • DNA double-strand breaks induced by mammographic screening procedures in human mammary epithelial cells
    • doi: 10.3109/09553002.2011.608410.
    • Colin C, Devic C, Noël A, Rabilloud M, Zabot MT, Pinet-Isaac S, et al. DNA double-strand breaks induced by mammographic screening procedures in human mammary epithelial cells. Int J Radiat Biol 2011;87:1103-12. doi: 10.3109/09553002.2011.608410.
    • (2011) Int J Radiat Biol , vol.87 , pp. 1103-1112
    • Colin, C.1    Devic, C.2    Noël, A.3    Rabilloud, M.4    Zabot, M.T.5    Pinet-Isaac, S.6
  • 69
    • 84874117306 scopus 로고    scopus 로고
    • Office for National Statistics. London, UK: Office for National Statistics
    • Office for National Statistics. Breast cancer: incidence, mortality and survival. London, UK: Office for National Statistics; 2010.
    • (2010) Breast Cancer: Incidence, Mortality and Survival
  • 71
    • 0026081577 scopus 로고
    • Frequent chest X-ray fluoroscopy and breast cancer incidence among tuberculosis patients in Massachusetts
    • Boice JD Jr, Preston D, Davis FG, Monson RR. Frequent chest X-ray fluoroscopy and breast cancer incidence among tuberculosis patients in Massachusetts. Radiat Res 1991;125:214-22.
    • (1991) Radiat Res , vol.125 , pp. 214-222
    • Boice Jr., J.D.1    Preston, D.2    Davis, F.G.3    Monson, R.R.4
  • 73
    • 33750890045 scopus 로고    scopus 로고
    • Analysis of gene expression using gene sets discriminates cancer patients with and without late radiation toxicity
    • doi: 10.1371/journal.pmed.0030422
    • Svensson JP, Stalpers LJ, Esveldt-van Lange RE, Franken NA, Haveman J, Klein B, et al. Analysis of gene expression using gene sets discriminates cancer patients with and without late radiation toxicity. PLoS Med 2006;3:e422. doi: 10.1371/journal.pmed.0030422.
    • (2006) PLoS Med , vol.3
    • Svensson, J.P.1    Stalpers, L.J.2    Esveldt-van Lange, R.E.3    Franken, N.A.4    Haveman, J.5    Klein, B.6
  • 76
    • 58949092475 scopus 로고    scopus 로고
    • Normal tissue reactions to radiotherapy: Towards tailoring treatment dose by genotype
    • doi: 10.1038/nrc2587
    • Barnett GC, West CM, Dunning AM, Elliott RM, Coles CE, Pharoah PD, et al. Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype. Nat Rev Cancer 2009;9:134-42. doi: 10.1038/nrc2587.
    • (2009) Nat Rev Cancer , vol.9 , pp. 134-142
    • Barnett, G.C.1    West, C.M.2    Dunning, A.M.3    Elliott, R.M.4    Coles, C.E.5    Pharoah, P.D.6
  • 77
    • 77952572348 scopus 로고    scopus 로고
    • Tumor cell response to synchrotron microbeam radiation therapy differs markedly from cells in normal tissues
    • doi: 10.1016/j.ijrobp.2010.01.035
    • Crosbie JC, Anderson RL, Rothkamm K, Restall CM, Cann L, Ruwanpura S, et al. Tumor cell response to synchrotron microbeam radiation therapy differs markedly from cells in normal tissues. Int J Radiat Oncol Biol Phys 2010;77:886-94. doi: 10.1016/j.ijrobp.2010.01.035.
    • (2010) Int J Radiat Oncol Biol Phys , vol.77 , pp. 886-894
    • Crosbie, J.C.1    Anderson, R.L.2    Rothkamm, K.3    Restall, C.M.4    Cann, L.5    Ruwanpura, S.6
  • 78
    • 84855447566 scopus 로고    scopus 로고
    • In situ biological dose mapping estimates the radiation burden delivered to "spared" tissue between synchrotron x-ray microbeam radiotherapy tracks
    • doi: 10.1371/journal.pone.0029853
    • Rothkamm K, Crosbie JC, Daley F, Bourne S, Barber PR, Vojnovic B, et al. In situ biological dose mapping estimates the radiation burden delivered to "spared" tissue between synchrotron x-ray microbeam radiotherapy tracks. PLoS One 2012;7:e29853. doi: 10.1371/journal.pone.0029853.
    • (2012) PLoS One , vol.7
    • Rothkamm, K.1    Crosbie, J.C.2    Daley, F.3    Bourne, S.4    Barber, P.R.5    Vojnovic, B.6
  • 79
    • 79958137942 scopus 로고    scopus 로고
    • Inter-individual and inter-cell type variation in residual DNA damage after in vivo irradiation of human skin
    • doi: 10.1016/j.radonc.2011.04.009
    • Chua ML, Somaiah N, Bourne S, Daley F, A'Hern R, Nuta O, et al. Inter-individual and inter-cell type variation in residual DNA damage after in vivo irradiation of human skin. Radiother Oncol 2011;99: 225-30. doi: 10.1016/j.radonc.2011.04.009.
    • (2011) Radiother Oncol , vol.99 , pp. 225-230
    • Chua, M.L.1    Somaiah, N.2    Bourne, S.3    Daley, F.4    A'Hern, R.5    Nuta, O.6
  • 80
    • 58149180926 scopus 로고    scopus 로고
    • DNA doublestrand break repair of blood lymphocytes and normal tissues analysed in a preclinical mouse model: Implications for radiosensitivity testing
    • doi: 10.1158/1078-0432.CCR-07-5147.
    • Rübe CE, Grudzenski S, Kühne M, Dong X, Rief N, Löbrich M, et al. DNA doublestrand break repair of blood lymphocytes and normal tissues analysed in a preclinical mouse model: implications for radiosensitivity testing. Clin Cancer Res 2008;14: 6546-55. doi: 10.1158/1078-0432.CCR-07-5147.
    • (2008) Clin Cancer Res , vol.14 , pp. 6546-6555
    • Rübe, C.E.1    Grudzenski, S.2    Kühne, M.3    Dong, X.4    Rief, N.5    Löbrich, M.6
  • 81
    • 39049163047 scopus 로고    scopus 로고
    • Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance
    • DOI 10.1158/0008-5472.CAN-07-5472
    • Chan N, Koritzinsky M, Zhao H, Bindra R, Glazer PM, Powell S, et al. Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance. Cancer Res 2008;68:605-14. doi: 10.1158/0008-5472.CAN-07-5472. (Pubitemid 351380090)
    • (2008) Cancer Research , vol.68 , Issue.2 , pp. 605-614
    • Chan, N.1    Koritzinsky, M.2    Zhao, H.3    Bindra, R.4    Glazer, P.M.5    Powell, S.6    Belmaaza, A.7    Wouters, B.8    Bristow, R.G.9
  • 82
    • 34249676952 scopus 로고    scopus 로고
    • Radiosensitization by nitric oxide at low radiation doses
    • DOI 10.1667/RR0827.1
    • Wardman P, Rothkamm K, Folkes LK, Woodcock M, Johnston PJ. Radiosensitization by nitric oxide at low radiation doses. Radiat Res 2007;167:475-84. doi: 10.1667/RR0827.1. (Pubitemid 351292978)
    • (2007) Radiation Research , vol.167 , Issue.4 , pp. 475-484
    • Wardman, P.1    Rothkamm, K.2    Folkes, L.K.3    Woodcock, M.4    Johnston, P.J.5
  • 83
    • 33746123934 scopus 로고    scopus 로고
    • Tumors face NO problems?
    • DOI 10.1158/0008-5472.CAN-05-2900
    • Lancaster JR Jr, Xie K. Tumors face NO problems? Cancer Res 2006;66:6459-62. doi: 10.1158/0008-5472.CAN-05-2900. (Pubitemid 44085595)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6459-6462
    • Lancaster Jr., J.R.1    Xie, K.2
  • 84
    • 33644520906 scopus 로고    scopus 로고
    • Whole-brain radiotherapy with or without efaproxiral for the treatment of brain metastases: Determinants of response and its prognostic value for subsequent survival
    • REACH Study Group doi: 10.1016/j.ijrobp.2005.10.004.
    • Stea B, Suh JH, Boyd AP, Cagnoni PJ, Shaw E, REACH Study Group. Whole-brain radiotherapy with or without efaproxiral for the treatment of brain metastases: determinants of response and its prognostic value for subsequent survival. Int J Radiat Oncol Biol Phys 2006;64:1023-30. doi: 10.1016/j.ijrobp.2005.10.004.
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , pp. 1023-1030
    • Stea, B.1    Suh, J.H.2    Boyd, A.P.3    Cagnoni, P.J.4    Shaw, E.5
  • 86
    • 0032895783 scopus 로고    scopus 로고
    • Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: A Gynecologic Oncology Group and Southwest Oncology Group Study
    • Whitney CW, Sause W, Bundy BN, Malfetano JH, Hannigan EV, Fowler WC Jr, et al. Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: a gynecologic oncology group and southwest oncology group study. J Clin Oncol 1999;17:1339-48. (Pubitemid 29220838)
    • (1999) Journal of Clinical Oncology , vol.17 , Issue.5 , pp. 1339-1348
    • Whitney, C.W.1    Sause, W.2    Bundy, B.N.3    Malfetano, J.H.4    Hannigan, E.V.5    Fowler Jr., W.C.6    Clarke-Pearson, D.L.7    Liao, S.-Y.8
  • 87
    • 34347240794 scopus 로고    scopus 로고
    • Chemical Radiosensitizers for Use in Radiotherapy
    • DOI 10.1016/j.clon.2007.03.010, PII S0936655507005808
    • Wardman P. Chemical radiosensitizers for use in radiotherapy. Clin Oncol 2007;19: 397-417. doi: 10.1016/j.clon.2007.03.010. (Pubitemid 46995615)
    • (2007) Clinical Oncology , vol.19 , Issue.6 , pp. 397-417
    • Wardman, P.1
  • 88
    • 84866936319 scopus 로고    scopus 로고
    • The relationship between homologous recombination repair and the sensitivity of human epidermis to the size of daily doses over a 5-week course of breast radiotherapy
    • doi: 10.1158/1078-0432.CCR-10-3297
    • Somaiah N, Yarnold J, Daley F, Pearson A, Gothard L, Rothkamm K, et al. The relationship between homologous recombination repair and the sensitivity of human epidermis to the size of daily doses over a 5-week course of breast radiotherapy. Clin Cancer Res 2012;18:5479-88. doi: 10.1158/1078-0432.CCR-10- 3297.
    • (2012) Clin Cancer Res , vol.18 , pp. 5479-5488
    • Somaiah, N.1    Yarnold, J.2    Daley, F.3    Pearson, A.4    Gothard, L.5    Rothkamm, K.6
  • 89
    • 84869139020 scopus 로고    scopus 로고
    • Propensity score-based comparison of long-term outcomes with 3-dimensional conformal radiotherapy vs intensity-modulated radiotherapy for esophageal cancer
    • doi: 10.1016/j.ijrobp.2012.02.015
    • Lin SH, Wang L, Myles B, Thall PF, Hofstetter WL, Swisher SG, et al. Propensity score-based comparison of long-term outcomes with 3-dimensional conformal radiotherapy vs intensity-modulated radiotherapy for esophageal cancer. Int J Radiat Oncol Biol Phys 2012;84:1078-85. doi: 10.1016/j.ijrobp. 2012.02.015.
    • (2012) Int J Radiat Oncol Biol Phys , vol.84 , pp. 1078-1085
    • Lin, S.H.1    Wang, L.2    Myles, B.3    Thall, P.F.4    Hofstetter, W.L.5    Swisher, S.G.6
  • 90
    • 84873307700 scopus 로고    scopus 로고
    • Long-term survival and toxicity in patients treated with high-dose intensity modulated radiation therapy for localized prostate cancer
    • doi: 10.1016/j.ijrobp.2012.05.023.
    • Spratt DE, Pei X, Yamada J, Kollmeier MA, Cox B, Zelefsky MJ. Long-term survival and toxicity in patients treated with high-dose intensity modulated radiation therapy for localized prostate cancer. Int J Radiat Oncol Biol Phys 2013;85:686-92. doi: 10.1016/j.ijrobp.2012.05.023.
    • (2013) Int J Radiat Oncol Biol Phys , vol.85 , pp. 686-692
    • Spratt, D.E.1    Pei, X.2    Yamada, J.3    Kollmeier, M.A.4    Cox, B.5    Zelefsky, M.J.6
  • 91
    • 79957934431 scopus 로고    scopus 로고
    • Biological in-vivo measurement of dose distribution in patients' lymphocytes by gamma-H2AX immunofluorescence staining: 3D conformal-vs. Step-and-shoot IMRT of the prostate gland
    • doi: 10.1186/1748-717X-6-62
    • Zwicker F, Swartman B, Sterzing F, Major G, Weber K, Huber PE, et al. Biological in-vivo measurement of dose distribution in patients' lymphocytes by gamma-H2AX immunofluorescence staining: 3D conformal-vs. step-and-shoot IMRT of the prostate gland. Radiat Oncol 2011;6:62. doi: 10.1186/1748-717X-6-62.
    • (2011) Radiat Oncol , vol.6 , pp. 62
    • Zwicker, F.1    Swartman, B.2    Sterzing, F.3    Major, G.4    Weber, K.5    Huber, P.E.6
  • 92
    • 0032957001 scopus 로고    scopus 로고
    • Variability in the radiosensitivity of normal cells and tissues. Report from a workshop organised by the European Society for Therapeutic Radiology and Oncology in Edinburgh, UK, 19 September 1998
    • Bentzen SM, Hendry JH. Variability in the radiosensitivity of normal cells and tissues. Report from a workshop organised by the European society for therapeutic radiology and oncology in Edinburgh, UK, 19 September 1998. Intl J Radiat Biol 1999;75:513-17. (Pubitemid 29191550)
    • (1999) International Journal of Radiation Biology , vol.75 , Issue.4 , pp. 513-517
    • Bentzen, S.M.1    Hendry, J.H.2
  • 97
    • 44149120922 scopus 로고    scopus 로고
    • Evidence for significant heritability of apoptotic and cell cycle responses to ionising radiation
    • doi: 10.1007/s00439-008-0500-1
    • Finnon P, Robertson N, Dziwura S, Raffy C, Zhang W, Ainsbury L, et al. Evidence for significant heritability of apoptotic and cell cycle responses to ionising radiation. Hum Genet 2008;123:485-93. doi: 10.1007/s00439-008-0500-1.
    • (2008) Hum Genet , vol.123 , pp. 485-493
    • Finnon, P.1    Robertson, N.2    Dziwura, S.3    Raffy, C.4    Zhang, W.5    Ainsbury, L.6
  • 98
    • 33747201603 scopus 로고    scopus 로고
    • Heritability of DNA-damage-induced apoptosis and its relationship with age in lymphocytes from female twins
    • DOI 10.1038/sj.bjc.6603257, PII 6603257
    • Camplejohn RS, Hodgson S, Carter N, Kato BS, Spector TD. Heritability of DNA-damage-induced apoptosis and its relationship with age in lymphocytes from female twins. Br J Cancer 2006;95:520-4. doi: 10.1038/sj.bjc.6603257. (Pubitemid 44232562)
    • (2006) British Journal of Cancer , vol.95 , Issue.4 , pp. 520-524
    • Camplejohn, R.S.1    Hodgson, S.2    Carter, N.3    Kato, B.S.4    Spector, T.D.5
  • 103
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov J, et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999;286:531-7.
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1    Slonim, D.K.2    Tamayo, P.3    Huard, C.4    Gaasenbeek, M.5    Mesirov, J.6
  • 106
    • 33846862650 scopus 로고    scopus 로고
    • Gene expression changes in peripheral blood cells provide insight into the biological mechanisms associated with regimen-related toxicities in patients being treated for head and neck cancers
    • DOI 10.1016/j.oraloncology.2006.03.014, PII S1368837506000947
    • Sonis S, Haddad R, Posner M, Watkins B, Fey E, Morgan TV, et al. Gene expression changes in peripheral blood cells provide insight into the biological mechanisms associated with regimen-related toxicities in patients being treated for head and neck cancers. Oral Oncol 2007;43:289-300. (Pubitemid 46228015)
    • (2007) Oral Oncology , vol.43 , Issue.3 , pp. 289-300
    • Sonis, S.1    Haddad, R.2    Posner, M.3    Watkins, B.4    Fey, E.5    Morgan, T.V.6    Mookanamparambil, L.7    Ramoni, M.8
  • 107
    • 78650166256 scopus 로고    scopus 로고
    • DNA repair alterations in children with pediatric malignancies: Novel opportunities to identify patients at risk for high-grade toxicities
    • doi: 10.1016/j.ijrobp.2009.08.052.
    • Rübe CE, Fricke A, Schneider R, Simon K, Kühne M, Fleckenstein J, et al. DNA repair alterations in children with pediatric malignancies: novel opportunities to identify patients at risk for high-grade toxicities. Int J Radiat Oncol Biol Phys 2010;78:359-69. doi: 10.1016/j.ijrobp.2009.08.052.
    • (2010) Int J Radiat Oncol Biol Phys , vol.78 , pp. 359-369
    • Rübe, C.E.1    Fricke, A.2    Schneider, R.3    Simon, K.4    Kühne, M.5    Fleckenstein, J.6
  • 108
    • 84855169068 scopus 로고    scopus 로고
    • Prolonged expression of the γ-H2AX DNA repair biomarker correlates with excess acute and chronic toxicity from radiotherapy treatment
    • doi: 10.1002/ijc.25953.
    • Bourton EC, Plowman PN, Smith D, Arlett CF, Parris CN. Prolonged expression of the γ-H2AX DNA repair biomarker correlates with excess acute and chronic toxicity from radiotherapy treatment. Int J Cancer 2011;129:2928-34. doi: 10.1002/ijc.25953.
    • (2011) Int J Cancer , vol.129 , pp. 2928-2934
    • Bourton, E.C.1    Plowman, P.N.2    Smith, D.3    Arlett, C.F.4    Parris, C.N.5
  • 109
    • 81855185421 scopus 로고    scopus 로고
    • The impact of individual in vivo repair of DNA double-strand breaks on oral mucositis in adjuvant radiotherapy of head-and-neck cancer
    • doi: 10.1016/j.ijrobp.2010.08.004
    • Fleckenstein J, Kühne M, Seegmüller K, Derschang S, Melchior P, Gräber S. The impact of individual in vivo repair of DNA double-strand breaks on oral mucositis in adjuvant radiotherapy of head-and-neck cancer. Int J Radiat Oncol Biol Phys 2011;81:1465-72. doi: 10.1016/j.ijrobp.2010.08.004.
    • (2011) Int J Radiat Oncol Biol Phys , vol.81 , pp. 1465-1472
    • Fleckenstein, J.1    Kühne, M.2    Seegmüller, K.3    Derschang, S.4    Melchior, P.5    Gräber, S.6
  • 110
    • 78650122325 scopus 로고    scopus 로고
    • Lack of a correlation between H2AX foci kinetics in lymphocytes and the severity of acute normal tissue reactions during IMRT treatment for head and neck cancer
    • doi:10.3109/09553002.2010.518213
    • Werbrouck J, Duprez F, De Neve W, Thierens H. Lack of a correlation between H2AX foci kinetics in lymphocytes and the severity of acute normal tissue reactions during IMRT treatment for head and neck cancer. Int J Radiat Biol 2011;87:46-56. doi:10.3109/09553002.2010.518213.
    • (2011) Int J Radiat Biol , vol.87 , pp. 46-56
    • Werbrouck, J.1    Duprez, F.2    De Neve, W.3    Thierens, H.4
  • 111
    • 76649087375 scopus 로고    scopus 로고
    • Prediction of late normal tissue complications in RT treated gynaecological cancer patients: Potential of the gamma-H2AX foci assay and association with chromosomal radiosensitivity
    • Werbrouck J, De Ruyck K, Beels L, Vral A, Van Eijkeren M, De Neve W, et al. Prediction of late normal tissue complications in RT treated gynaecological cancer patients: potential of the gamma-H2AX foci assay and association with chromosomal radiosensitivity. Oncol Rep 2010;23:571-8.
    • (2010) Oncol Rep , vol.23 , pp. 571-578
    • Werbrouck, J.1    De Ruyck, K.2    Beels, L.3    Vral, A.4    Van Eijkeren, M.5    De Neve, W.6
  • 112
    • 0344873101 scopus 로고    scopus 로고
    • Individual radiosensitivity measured with lymphocytes may be used to predict the risk of fibrosis after radiotherapy for breast cancer
    • Hoeller U, Borgmann K, Bonacker M, Kuhlmey A, Bajrovic A, Jung H, et al. Individual radiosensitivity measured with lymphocytes may be used to predict the risk of fibrosis after radiotherapy for breast cancer. Radiother Oncol 2003;69:137-44.
    • (2003) Radiother Oncol , vol.69 , pp. 137-144
    • Hoeller, U.1    Borgmann, K.2    Bonacker, M.3    Kuhlmey, A.4    Bajrovic, A.5    Jung, H.6
  • 113
    • 41749104006 scopus 로고    scopus 로고
    • Individual radiosensitivity measured with lymphocytes may predict the risk of acute reaction after radiotherapy
    • doi: 10.1016/j.ijrobp.2008.01.007
    • Borgmann K, Hoeller U, Nowack S, Bernhard M, Röper B, Brackrock S, et al. Individual radiosensitivity measured with lymphocytes may predict the risk of acute reaction after radiotherapy. Int J Radiat Oncol Biol Phys 2008;71:256-64. doi: 10.1016/j.ijrobp.2008.01.007.
    • (2008) Int J Radiat Oncol Biol Phys , vol.71 , pp. 256-264
    • Borgmann, K.1    Hoeller, U.2    Nowack, S.3    Bernhard, M.4    Röper, B.5    Brackrock, S.6
  • 114
    • 79960367184 scopus 로고    scopus 로고
    • Residual DNA and chromosomal damage in ex vivo irradiated blood lymphocytes correlated with late normal tissue response to breast radiotherapy
    • doi: 0.1016/j.radonc.2011.05.071
    • Chua ML, Somaiah N, A'Hern R, Davies S, Gothard L, Yarnold J, et al. Residual DNA and chromosomal damage in ex vivo irradiated blood lymphocytes correlated with late normal tissue response to breast radiotherapy. Radiother Oncol 2011;99: 362-6. doi: 0.1016/j.radonc.2011.05.071.
    • (2011) Radiother Oncol , vol.99 , pp. 362-366
    • Chua, M.L.1    Somaiah, N.2    A'Hern, R.3    Davies, S.4    Gothard, L.5    Yarnold, J.6
  • 117
    • 84855321526 scopus 로고    scopus 로고
    • Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: A prospective analysis study
    • doi: 10.1016/S1470-2045(11)70302-3
    • Barnett GC, Coles CE, Elliott RM, Baynes C, Luccarini C, Conroy D, et al. Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study. Lancet Oncol 2012;13:65-77. doi: 10.1016/S1470-2045(11)70302-3.
    • (2012) Lancet Oncol , vol.13 , pp. 65-77
    • Barnett, G.C.1    Coles, C.E.2    Elliott, R.M.3    Baynes, C.4    Luccarini, C.5    Conroy, D.6


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