Persistence of translocation frequencies in blood lymphocytes following radiotherapy: Implications for retrospective radiation biodosimetry

Journal of Radiological Protection

Volumn 23, Issue 4, 2003, Pages 423-430

  Tawn, E Janet ^a   Whitehouse, Caroline A ^a  

^a WESTLAKES RESEARCH INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOMES; DOSIMETRY; PATIENT TREATMENT; RADIATION PROTECTION; RADIOTHERAPY; REFLECTION;

BLOOD CULTURE;

BLOOD;

IRIDIUM;

ADULT; ARTICLE; BLADDER CANCER; BREAST CANCER; CANCER; CANCER RADIOTHERAPY; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME G BAND; CHROMOSOME TRANSLOCATION; CLINICAL ARTICLE; CONTROLLED STUDY; DICENTRIC CHROMOSOME; DOSIMETRY; DRUG IMPLANT; FEMALE; HODGKIN DISEASE; HUMAN; HUMAN CELL; HYPOPHYSIS TUMOR; LARYNX CANCER; LYMPHOCYTE; LYMPHOCYTE COUNT; LYMPHOCYTE CULTURE; MALE; NOSE CANCER; OVARY CANCER; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE;

ADULT; FEMALE; HUMANS; LYMPHOCYTES; MALE; MIDDLE AGED; NEOPLASMS; RADIOMETRY; RADIOTHERAPY DOSAGE; TIME FACTORS; TRANSLOCATION, GENETIC;

EID: 0742271722     PISSN: 09524746     EISSN: None     Source Type: Journal    
DOI: 10.1088/0952-4746/23/4/005     Document Type: Article

References (18)

1. Bothwell A M, Whitehouse C A and Tawn E J 2000 The application of FISH for chromosome aberration analysis in relation to radiation exposure Radiat. Prot. Dosim. 88 7-14
2. 60Co gamma ray dose-response for chromosomal aberrations in human lymphocytes analysed by FISH; Applicability to biological dosimetry. Int. J. Radiat. Biol. 75 1215-22
3. Guerrero-Carbajal Y C, Moquet J E, Edwards A and Lloyd D C 1998 The persistence of FISH translocations for retrospective biological dosimetry after simulated whole or partial body irradiation. Radiat. Prot. Dosim. 76, 159-68
4. 60Co gamma-irradiation. Int. J. Radiat. Biol. 77 797-804
5. Huber R, Braselmann H, Kulka U, Schumacher-Georgiadou V, Bayerl A, Molls M and Bauchinger M 1999 Follow-up analysis of translocation and dicentric frequencies, measured by FISH-chromosome painting in breast cancer patients after partial-body radiotherapy with little bone marrow exposure Mutat. Res. 446 103-9
6. Legal J D, De Crevoisier R, Lartigau E, Morsli K, Dossou J, Chavaudra N, Sanfilippo N, Bourhis J, Eschwege F and Parmentier C 2002 Chromosomal aberrations induced by chemotherapy and radiotherapy in lymphocytes from patients with breast carcinoma. Int. J. Radiat. Biol. 52 1186-95
7. Lindholm C, Tekkel M, Veidebaum T, Ilus T and Salomaa S 1998 Persistence of translocations after accidental exposure to ionizing radiation. Int. J. Radiat. Biol. 74 565-71
8. Lindholm C, Romm H, Stephan G, Schmid E, Moquet J and Edwards A 2002 Intercomparison of translocation and dicentric frequencies between laboratories in a follow-up of the radiological accident in Estonia Int. J. Radiat. Biol. 78 883-90
9. Littlefield L G, McFee A F, Sayer A M, O'Neill J P, Kleinerman R A and Maor H 2000 Induction and persistence of chromosome aberrations in human lymphocytes exposed to neutrons in vitro or in vivo: Implication of findings in 'retrospective' biological dosimetry Radiat. Prot. Dosim. 88, 59-68
10. Lloyd D C 1998 New developments in chromosomal analysis for biological dosimetry Radiat. Prot. Dosim. 77 33-6
11. Lloyd D C, Moquet J E, Oram S, Edwards A A and Lucas J N 1998 Accidental intake of tritiated water: A cytogenetic follow-up case on translocation stability and dose reconstruction. Int. J. Radiat. Biol. 73, 543-7
12. Lucas J N, Awa A, Straume T, Poggensee M, Kodama Y, Nakano M, Ohtaki K, Weier H U, Pinkel D, Gray J and Littlefield G 1992 Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation Int. J. Radiat. Biol. 62, 53-63
13. 137Cesium-induced chromosome aberrations analyzed by fluorescence in situ hybridization: Eight years follow-up of the Goiania radiation accident victims Mutat. Res. 400 299-312
14. Puerto S, Marcos R, Ramirez M J, Galofre P, Creus A and Surralles J 2000 Equal induction and persistence of chromosome aberrations involving chromosomes 1, 4, and 10 in thyroid cancer patients treated with radioactive iodine Mutat. Res. 469 147-58
15. Rubin C M, Robison L L, Nesbit M E Jr and Arthur D C 1986 Cytogenetic studies of long-term survivors of childhood acute lymphoblastic leukemia: A follow-up report Med. Pediatr. Oncol. 14 295-9
16. Schmidberger H, Virsik-Koepp P, Rave-Frank M, Reinosch K-R, Pradier O, Munzel U and Hess C F 2001 Reciprocal translocations in patients with testicular seminoma before and after radiotherapy Int. J. Radiat. Oncol. Biol. Phys. 50 857-64
17. Spruill M D, Nelson D O, Ramsey M J, Nath J and Tucker J D 2000 Lifetime persistence and clonality of chromosome aberrations in the peripheral blood of mice acutely exposed to ionising radiation. Radiat. Res. 153 110-21
18. Stephan G and Pressl S 1997 Chromosome aberrations in human lymphocytes analysed by fluorescence in situ hybridization after in vitro irradiation, and in radiation workers, 11 years after an accidental radiation exposure Int. J. Radiat. Biol. 71 293-9