Long-term persistence of translocations in stable lymphocytes from victims of a radiological accident

International Journal of Radiation Biology

Volumn 80, Issue 8, 2004, Pages 559-566

  Lindholm, C ^a   Edwards, A ^b  

^a STUK RADIATION AND NUCLEAR SAFETY AUTHORITY   (Finland)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

7 AMINO 4 METHYLCOUMARIN 3 ACETIC ACID; COUMARIN DERIVATIVE; FLUORESCEIN ISOTHIOCYANATE; UNCLASSIFIED DRUG;

ARTICLE; CALIBRATION; CHROMOSOME 1; CHROMOSOME 2; CHROMOSOME 4; CHROMOSOME ABERRATION; CHROMOSOME PAINTING; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DOSIMETRY; ESTONIA; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; LYMPHOCYTE; METAPHASE CHROMOSOME; PRIORITY JOURNAL; RADIATION ACCIDENT; RING CHROMOSOME; TIME;

ACCIDENTS, RADIATION; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LYMPHOCYTES; TRANSLOCATION, GENETIC;

EID: 4644308587     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/09553000412331283498     Document Type: Article

References (22)

1. BUCKTON, K. E. and PIKE, M. C., 1964, Time in culture. An important variable in studying in vivo radiation-induced damage in man. International Journal of Radiation Biology, 8, 439-452.
2. DURAN, A., BARQUINERO, J. F., CABALLIN, M. R., RABAS, M., PUIG, P., EGOXCUE, J. and BARRIOS, L., 2002, The suitability of FISH painting techniques for the detection of partial-body irradiations for biological dosimetry. Radiation Research, 157, 461-468.
3. 60Co gamma-ray dose-response for chromosomal aberrations in human lymphocytes analysed by FISH; applicability to biological dosimetry. International Journal of Radiation Biology, 75, 1215-1222.
4. GARDNER, S. N. and TUCKER, J. D., 2002, The cellular lethality of radiation-induced chromosome translocations in human lymphocytes. Radiation Research, 157, 539-552.
5. GUERRERO-CARBAJAL, Y. C., MOQUET, J. E., EDWARDS, A. A. and LLOYD, D. C., 1998, The persistence of FISH translocations for retrospective biological dosimetry after simulated whole or partial body irradiation. Radiation Protection Dosimetry, 76, 159-168.
6. HANDE, M. P. and NATARAJAN, A. T., 1998, Induction and persistence of cytogenetic damage in mouse splenocytes following whole-body X-irradiation analysed by fluorescence in situ hybridization. IV. Dose-response. International Journal of Radiation Biology, 74, 441-448.
7. IAEA, 1998, The Radiological Accident in Tammiku (Vienna: IAEA).
8. LINDHOLM, C., ROMM, H., STEPHAN, G., SCHMID, E., MOCQUET, J. and EDWARDS, A., 2002, Intercomparison of translocation and dicentric frequencies between laboratories in a follow-up of the radiological accident in Estonia. International Journal of Radiation Biology, 78, 883-890.
9. LINDHOLM, C., TEKKEL, M., VEIDEBAUM, T., ILUS, T. and SALOMAA, S., 1998, Persistence of translocations after accidental exposure to ionizing radiation. International Journal of Radiation Biology, 74, 565-571.
10. LINDHOLM, C., SALOMAA, S., TEKKEL, M., PAILE, W., KOIVISTOINEN, A., ILUS, T. and VEIDEBAUM, T., 1996, Biodosimetry after accidental radiation exposure by conventional chromosome analysis and FISH. International Journal of Radiation Biology, 70, 647-656.
11. LLOYD, D. C., MOQUET, J. E., ORAM, S., EDWARDS, A. A. and LUCAS, J. N., 1998, Accidental intake of tritiated water: a cytogenetic follow-up case on translocation stability and dose reconstruction. International Journal of Radiation Biology, 73, 543-547.
12. LUCAS, J. N., HILL, F. S., BURK, C. E., Cox, A. B. and STRAUME, T., 1996, Stability of the translocation frequency following whole-body irradiation measured in rhesus monkeys. International Journal of Radiation Biology, 70, 309-318.
13. LUCAS, J. N., AWA, A., STRAUME, T., POGGENSEE, M., KODAMA, Y., NAKANO, M., OHTAKI, K., WEIER, H. U., PINKEL, D., GRAY, J. and LITTLEFIELD, L. G., 1992, Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation. International Journal of Radiation Biology, 62, 53-63.
14. MATSUMOTO, K., RAMSEY, M. J., NELSON, D. O. and TUCKER, J. D., 1998, Persistence of radiation-induced translocations in human peripheral blood determined by chromosome painting. Radiation Research, 149, 602-613.
15. MORTON, N. E., 1991, Parameters of the human genome. Proceedings of the National Academy of Sciences, USA, 88, 7474-7476.
16. 137Cesium- induced chromosome aberrations analyzed by fluorescence in situ hybridization: eight years follow up of the Goiania radiation accident victims. Mutation Research, 400, 299-312.
17. SALASSIDIS, K., GEORGIADOU-SCHUMACHER, V., BRASELMANN, H., MÜLLER, P., PETER, R. U. and BAUCHINGER, M., 1995, Chromosome painting in highly irradiated Chernobyl victims: a follow-up study to evaluate the stability of symmetrical translocations and the influence of clonal aberrations for retrospective dose estimation. International Journal of Radiation Biology, 68, 257-262.
18. SASAKI, M. S. and MIYATA, H., 1968, Biological dosimetry in atom bomb survivors. Nature (London), 220, 1189-1193.
19. SPRUILL, M. D., NELSON, D. O., RAMSEY, M. J., NATH, J. and TUCKER, J. D., 2000, Lifetime persistence and clonality of chromosome aberrations in the peripheral blood of mice acutely exposed to ionizing radiation. Radiation Research, 153, 110-121.
20. STEPHAN, G. and PRESSL, S., 1997, Chromosome aberrations in human lymphocytes analysed by fluorescence in situ hybridization after in vitro irradiation, and in radiation workers, 11 years after an accidental radiation exposure. International Journal of Radiation Biology, 71, 293-299.
21. TUCKER, J. D., BRENEMAN, J. W., BRINER, J. F., EVELETH, G. G., LANGLOIS, R. G. and MOORE, II, D. H., 1997, Persistence of radiation-induced translocations in rat peripheral blood determined by chromosome painting. Environmental and Molecular Mutagenesis, 30, 264-272.
22. TUCKER, J. D., MORGAN, W. F., AWA, A. A., BAUCHINGER, M., BLAKEY, D., CORNFORTH, M. N., LITTLEFIELD, L. G., NATARAJAN, A. T. and SHASSERRE, C., 1995, A proposed system for scoring structural aberrations detected by chromosome painting. Cytogenetics Cell Genetics, 68, 211-221.