-
1
-
-
77951776829
-
Alzheimer's Disease: Strategies for Disease Modification
-
Citron, M. Alzheimer's Disease: Strategies for Disease Modification Nat. Rev. Drug Discovery 2010, 9, 387-398
-
(2010)
Nat. Rev. Drug Discovery
, vol.9
, pp. 387-398
-
-
Citron, M.1
-
2
-
-
77955924937
-
Immunotherapy for Alzheimer's Disease
-
Solomon, B.; Frenkel, D. Immunotherapy for Alzheimer's Disease Neuropharmacology 2010, 59, 303-309
-
(2010)
Neuropharmacology
, vol.59
, pp. 303-309
-
-
Solomon, B.1
Frenkel, D.2
-
3
-
-
33847662852
-
Soluble Protein Oligomers in Neurodegeneration: Lessons from the Alzheimer's Amyloid β-Peptide
-
Haass, C.; Selkoe, D. Soluble Protein Oligomers in Neurodegeneration: Lessons from the Alzheimer's Amyloid β-Peptide Nat. Rev. Mol. Cell. Biol. 2007, 8, 101-112
-
(2007)
Nat. Rev. Mol. Cell. Biol.
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.2
-
4
-
-
16944362157
-
Mutant Presenilins of Alzheimer's Disease Increase Production of 42-Residue Amyloid β-Protein in Both Transfected Cells and Transgenic Mice
-
Citron, M.; Westaway, D.; Xia, W.; Carlson, G.; Diehl, T.; Levesque, G.; Johnson-wood, K.; Lee, M.; Seubert, P.; Davis, A. Mutant Presenilins of Alzheimer's Disease Increase Production of 42-Residue Amyloid β-Protein in Both Transfected Cells and Transgenic Mice Nat. Med. 1997, 3, 67-72
-
(1997)
Nat. Med.
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
-
5
-
-
0037168655
-
A Structural Model for Alzheimer's β-Amyloid Fibrils Based on Experimental Constraints from Solid State NMR
-
Petkova, A. T.; Ishii, Y.; Balbach, J. J.; Antzutkin, O. N.; Leapman, R. D.; Delaglio, F.; Tycko, R. A Structural Model for Alzheimer's β-Amyloid Fibrils Based on Experimental Constraints from Solid State NMR Proc. Natl. Acad. Sci. U.S.A. 2002, 99, 16742-16747
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 16742-16747
-
-
Petkova, A.T.1
Ishii, Y.2
Balbach, J.J.3
Antzutkin, O.N.4
Leapman, R.D.5
Delaglio, F.6
Tycko, R.7
-
6
-
-
0034649352
-
Amyloid Fibril Formation by Aβ16-22, a Seven-Residue Fragment of the Alzheimer's β-Amyloid Peptide, and Structural Characterization by Solid State NMR
-
Balbach, J. J.; Ishii, Y.; Antzutkin, O. N.; Leapman, R. D.; Rizzo, N. W.; Dyda, F.; Reed, J.; Tycko, R. Amyloid Fibril Formation by Aβ16-22, a Seven-Residue Fragment of the Alzheimer's β-Amyloid Peptide, and Structural Characterization by Solid State NMR Biochemistry 2000, 39, 13748-13759
-
(2000)
Biochemistry
, vol.39
, pp. 13748-13759
-
-
Balbach, J.J.1
Ishii, Y.2
Antzutkin, O.N.3
Leapman, R.D.4
Rizzo, N.W.5
Dyda, F.6
Reed, J.7
Tycko, R.8
-
7
-
-
34249290108
-
Atomic Structures of Amyloid Cross-β Spines Reveal Varied Steric Zippers
-
Sawaya, M.; Sambashivan, S.; Nelson, R.; Ivanova, M.; Sievers, S.; Apostol, M.; Thompson, M.; Balbirnie, M.; Wiltzius, J.; McFarlane, H. Atomic Structures of Amyloid Cross-β Spines Reveal Varied Steric Zippers Nature 2007, 447, 453-457
-
(2007)
Nature
, vol.447
, pp. 453-457
-
-
Sawaya, M.1
Sambashivan, S.2
Nelson, R.3
Ivanova, M.4
Sievers, S.5
Apostol, M.6
Thompson, M.7
Balbirnie, M.8
Wiltzius, J.9
McFarlane, H.10
-
8
-
-
0028920098
-
Prolines and Amyloidogenicity in Fragments of the Alzheimer's Peptide β/A4
-
Wood, S.; Wetzel, R.; Martin, J.; Hurle, M. Prolines and Amyloidogenicity in Fragments of the Alzheimer's Peptide β/A4 Biochemistry 1995, 34, 724-730
-
(1995)
Biochemistry
, vol.34
, pp. 724-730
-
-
Wood, S.1
Wetzel, R.2
Martin, J.3
Hurle, M.4
-
9
-
-
40049110948
-
Mutations Enhance the Aggregation Propensity of the Alzheimer's Aβ Peptide
-
Kim, W.; Hecht, M. H. Mutations Enhance the Aggregation Propensity of the Alzheimer's Aβ Peptide J. Mol. Biol. 2008, 377, 565-574
-
(2008)
J. Mol. Biol.
, vol.377
, pp. 565-574
-
-
Kim, W.1
Hecht, M.H.2
-
10
-
-
0029854533
-
Point Substitution in the Central Hydrophobic Cluster of a Human β-Amyloid Congener Disrupts Peptide Folding and Abolishes Plaque Competence
-
Esler, W. P.; Stimson, E. R.; Ghilardi, J. R.; Lu, Y. A.; Felix, A. M.; Vinters, H. V.; Mantyh, P. W.; Lee, J. P.; Maggio, J. E. Point Substitution in the Central Hydrophobic Cluster of a Human β-Amyloid Congener Disrupts Peptide Folding and Abolishes Plaque Competence Biochemistry 1996, 35, 13914-13921
-
(1996)
Biochemistry
, vol.35
, pp. 13914-13921
-
-
Esler, W.P.1
Stimson, E.R.2
Ghilardi, J.R.3
Lu, Y.A.4
Felix, A.M.5
Vinters, H.V.6
Mantyh, P.W.7
Lee, J.P.8
Maggio, J.E.9
-
11
-
-
67849106670
-
Amyloid-β Protein Oligomerization and the Importance of Tetramers and Dodecamers in the Aetiology of Alzheimer's Disease
-
Bernstein, S. L.; Dupuis, N. F.; Lazo, N. D.; Wyttenbach, T.; Condron, M. M.; Bitan, G.; Teplow, D. B.; Shea, J.-E.; Ruotolo, B. T.; Robinson, C. V. Amyloid-β Protein Oligomerization and the Importance of Tetramers and Dodecamers in the Aetiology of Alzheimer's Disease Nat. Chem. 2009, 1, 326-331
-
(2009)
Nat. Chem.
, vol.1
, pp. 326-331
-
-
Bernstein, S.L.1
Dupuis, N.F.2
Lazo, N.D.3
Wyttenbach, T.4
Condron, M.M.5
Bitan, G.6
Teplow, D.B.7
Shea, J.-E.8
Ruotolo, B.T.9
Robinson, C.V.10
-
12
-
-
33750603844
-
Alzheimer's Centennial Legacy: Prospects for Rational Therapeutic Intervention Targeting the Aβ Amyloid Pathway
-
Masters, C.; Beyreuther, K. Alzheimer's Centennial Legacy: Prospects for Rational Therapeutic Intervention Targeting the Aβ Amyloid Pathway Brain 2006, 129, 2823-2839
-
(2006)
Brain
, vol.129
, pp. 2823-2839
-
-
Masters, C.1
Beyreuther, K.2
-
13
-
-
77950941375
-
Amyloid-β Fibrillogenesis: Structural Insight and Therapeutic Intervention
-
Dasilva, K. A.; Shaw, J. E.; McLaurin, J. Amyloid-β Fibrillogenesis: Structural Insight and Therapeutic Intervention Exp. Neurol. 2010, 223, 311-321
-
(2010)
Exp. Neurol.
, vol.223
, pp. 311-321
-
-
Dasilva, K.A.1
Shaw, J.E.2
McLaurin, J.3
-
14
-
-
52249085846
-
A Molecular Dynamics Study of the Interaction of D-Peptide Amyloid Inhibitors with Their Target Sequence Reveals a Potential Inhibitory Pharmacophore Conformation
-
Esteras-Chopo, A.; Morra, G.; Moroni, E.; Serrano, L.; de la Paz, M. L.; Colombo, G. A Molecular Dynamics Study of the Interaction of D-Peptide Amyloid Inhibitors with Their Target Sequence Reveals a Potential Inhibitory Pharmacophore Conformation J. Mol. Biol. 2008, 383, 266-280
-
(2008)
J. Mol. Biol.
, vol.383
, pp. 266-280
-
-
Esteras-Chopo, A.1
Morra, G.2
Moroni, E.3
Serrano, L.4
De La Paz, M.L.5
Colombo, G.6
-
15
-
-
33749522024
-
Peptide-Based Inhibitors of Amyloid Assembly
-
Sciarretta, K.; Gordon, D.; Meredith, S. Peptide-Based Inhibitors of Amyloid Assembly Methods Enzymol. 2006, 413, 273-312
-
(2006)
Methods Enzymol.
, vol.413
, pp. 273-312
-
-
Sciarretta, K.1
Gordon, D.2
Meredith, S.3
-
16
-
-
0042818327
-
Stereoselective Interactions of Peptide Inhibitors with the β-Amyloid Peptide
-
Chalifour, R.; McLaughlin, R.; Lavoie, L.; Morissette, C.; Tremblay, N.; Boulé, M.; Sarazin, P.; Stéa, D.; Lacombe, D.; Tremblay, P. Stereoselective Interactions of Peptide Inhibitors with the β-Amyloid Peptide J. Biol. Chem. 2003, 278, 34874-34881
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34874-34881
-
-
Chalifour, R.1
McLaughlin, R.2
Lavoie, L.3
Morissette, C.4
Tremblay, N.5
Boulé, M.6
Sarazin, P.7
Stéa, D.8
Lacombe, D.9
Tremblay, P.10
-
17
-
-
0036305837
-
Design of Peptide-Based Inhibitors of Human Islet Amyloid Polypeptide Fibrillogenesis
-
Scrocchi, L.; Chen, Y.; Waschuk, S.; Wang, F.; Cheung, S.; Darabie, A.; McLaurin, J.; Fraser, P. Design of Peptide-Based Inhibitors of Human Islet Amyloid Polypeptide Fibrillogenesis J. Mol. Biol. 2002, 318, 697-706
-
(2002)
J. Mol. Biol.
, vol.318
, pp. 697-706
-
-
Scrocchi, L.1
Chen, Y.2
Waschuk, S.3
Wang, F.4
Cheung, S.5
Darabie, A.6
McLaurin, J.7
Fraser, P.8
-
18
-
-
36049022567
-
New Insights into the Mechanism of Alzheimer Amyloid-β Fibrillogenesis Inhibition by N-Methylated Peptides
-
Soto, P.; Griffin, M.; Shea, J.-E. New Insights into the Mechanism of Alzheimer Amyloid-β Fibrillogenesis Inhibition by N-Methylated Peptides Biophys. J. 2007, 93, 3015-3025
-
(2007)
Biophys. J.
, vol.93
, pp. 3015-3025
-
-
Soto, P.1
Griffin, M.2
Shea, J.-E.3
-
19
-
-
0034700471
-
Aβ Peptide Immunization Reduces Behavioural Impairment and Plaques in a Model of Alzheimer's Disease
-
Janus, C.; Pearson, J.; McLaurin, J.; Mathews, P. M.; Jiang, Y.; Schmidt, S. D.; Chishti, M. A.; Horne, P.; Heslin, D.; French, J. Aβ Peptide Immunization Reduces Behavioural Impairment and Plaques in a Model of Alzheimer's Disease Nature 2000, 408, 979-982
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
Chishti, M.A.7
Horne, P.8
Heslin, D.9
French, J.10
-
20
-
-
59849083504
-
Inhibition of α-synuclein Fibril Assembly by Small Molecules: Analysis Using Epitope-Specific Antibodies
-
Masuda, M.; Hasegawa, M.; Nonaka, T.; Oikawa, T.; Yonetani, M.; Yamaguchi, Y.; Kato, K.; Hisanaga, S.; Goedert, M. Inhibition of α-synuclein Fibril Assembly by Small Molecules: Analysis Using Epitope-Specific Antibodies FEBS Lett. 2009, 583, 787-791
-
(2009)
FEBS Lett.
, vol.583
, pp. 787-791
-
-
Masuda, M.1
Hasegawa, M.2
Nonaka, T.3
Oikawa, T.4
Yonetani, M.5
Yamaguchi, Y.6
Kato, K.7
Hisanaga, S.8
Goedert, M.9
-
21
-
-
77952674128
-
Natural Polyphenols as Inhibitors of Amyloid Aggregation. Molecular Dynamics Study of GNNQQNY Heptapeptide Decamer
-
Berhanu, W.; Masunov, A. Natural Polyphenols as Inhibitors of Amyloid Aggregation. Molecular Dynamics Study of GNNQQNY Heptapeptide Decamer Biophys. Chem. 2010, 149, 12-21
-
(2010)
Biophys. Chem.
, vol.149
, pp. 12-21
-
-
Berhanu, W.1
Masunov, A.2
-
22
-
-
44849087785
-
EGCG Redirects Amyloidogenic Polypeptides into Unstructured, Off-Pathway Oligomers
-
Ehrnhoefer, D. E.; Bieschke, J.; Boeddrich, A.; Herbst, M.; Masino, L.; Lurz, R.; Engemann, S.; Pastore, A.; Wanker, E. E. EGCG Redirects Amyloidogenic Polypeptides into Unstructured, Off-Pathway Oligomers Nat. Struct. Mol. Biol. 2008, 15, 558-566
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 558-566
-
-
Ehrnhoefer, D.E.1
Bieschke, J.2
Boeddrich, A.3
Herbst, M.4
Masino, L.5
Lurz, R.6
Engemann, S.7
Pastore, A.8
Wanker, E.E.9
-
23
-
-
64349107868
-
Small Molecule Inhibitors of Aβ-Aggregation and Neurotoxicity
-
Hawkes, C.; Ng, V.; McLaurin, J. Small Molecule Inhibitors of Aβ-Aggregation and Neurotoxicity Drug Dev. Res. 2009, 70, 111-124
-
(2009)
Drug Dev. Res.
, vol.70
, pp. 111-124
-
-
Hawkes, C.1
Ng, V.2
McLaurin, J.3
-
24
-
-
34249860495
-
Small Molecule Inhibitors of Aggregation Indicate That Amyloid β Oligomerization and Fibrillization Pathways Are Independent and Distinct
-
Necula, M.; Kayed, R.; Milton, S.; Glabe, C. Small Molecule Inhibitors of Aggregation Indicate That Amyloid β Oligomerization and Fibrillization Pathways Are Independent and Distinct J. Biol. Chem. 2007, 282, 10311-10324
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 10311-10324
-
-
Necula, M.1
Kayed, R.2
Milton, S.3
Glabe, C.4
-
25
-
-
41549105851
-
Modulation of Amyloid-β Aggregation and Toxicity by Inosose Stereoisomers
-
Nitz, M.; Fenili, D.; Darabie, A. A.; Wu, L.; Cousins, J. E.; McLaurin, J. Modulation of Amyloid-β Aggregation and Toxicity By Inosose Stereoisomers FEBS J. 2008, 275, 1663-1674
-
(2008)
FEBS J.
, vol.275
, pp. 1663-1674
-
-
Nitz, M.1
Fenili, D.2
Darabie, A.A.3
Wu, L.4
Cousins, J.E.5
McLaurin, J.6
-
26
-
-
33745922350
-
Cyclohexanehexol Inhibitors of Aβ Aggregation Prevent and Reverse Alzheimer Phenotype in a Mouse Model
-
McLaurin, J.; Kierstead, M. E.; Brown, M. E.; Hawkes, C. A.; Lambermon, M. H. L.; Phinney, A. L.; Darabie, A. A.; Cousins, J. E.; French, J. E.; Lan, M. F. Cyclohexanehexol Inhibitors of Aβ Aggregation Prevent and Reverse Alzheimer Phenotype in a Mouse Model Nat. Med. 2006, 12, 801-808
-
(2006)
Nat. Med.
, vol.12
, pp. 801-808
-
-
McLaurin, J.1
Kierstead, M.E.2
Brown, M.E.3
Hawkes, C.A.4
Lambermon, M.H.L.5
Phinney, A.L.6
Darabie, A.A.7
Cousins, J.E.8
French, J.E.9
Lan, M.F.10
-
27
-
-
0034674785
-
Inositol Stereoisomers Stabilize an Oligomeric Aggregate of Alzheimer Amyloid β Peptide and Inhibit Aβ-Induced Toxicity
-
McLaurin, J.; Golomb, R.; Jurewicz, A.; Antel, J.; Fraser, P. Inositol Stereoisomers Stabilize an Oligomeric Aggregate of Alzheimer Amyloid β Peptide and Inhibit Aβ-Induced Toxicity J. Biol. Chem. 2000, 275, 18495-18502
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18495-18502
-
-
McLaurin, J.1
Golomb, R.2
Jurewicz, A.3
Antel, J.4
Fraser, P.5
-
28
-
-
34249867410
-
Properties of scyllo-Inositol as a Therapeutic Treatment of AD-Like Pathology
-
Fenili, D.; Brown, M.; Rappaport, R.; McLaurin, J. Properties of scyllo-Inositol as a Therapeutic Treatment of AD-Like Pathology J. Mol. Med. 2007, 85, 603-611
-
(2007)
J. Mol. Med.
, vol.85
, pp. 603-611
-
-
Fenili, D.1
Brown, M.2
Rappaport, R.3
McLaurin, J.4
-
29
-
-
84864300783
-
-
Advances in Pharmacology, Michaelis, M. Michaelis, E. Elsevier Science: Amsterdam, The Netherlands
-
Ma, K.; Thomason, L. A. M.; McLaurin, J. In Current State of Alzheimer's Disease Research and Therapeutics; Advances in Pharmacology, Vol. 64; Michaelis, M.; Michaelis, E., Eds.; Elsevier Science: Amsterdam, The Netherlands, 2012; pp 177-212.
-
(2012)
Current State of Alzheimer's Disease Research and Therapeutics
, vol.64
, pp. 177-212
-
-
Ma, K.1
Thomason, L.A.M.2
McLaurin, J.3
-
30
-
-
0036677944
-
Inositol and Higher Inositol Phosphates in Neural Tissues: Homeostasis, Metabolism and Functional Significance
-
Fisher, S. K.; Novak, J. E.; Agranoff, B. W. Inositol and Higher Inositol Phosphates in Neural Tissues: Homeostasis, Metabolism and Functional Significance J. Neurochem. 2002, 82, 736-754
-
(2002)
J. Neurochem.
, vol.82
, pp. 736-754
-
-
Fisher, S.K.1
Novak, J.E.2
Agranoff, B.W.3
-
31
-
-
82255179817
-
A Phase 2 Randomized Trial of ELND005, scyllo-Inositol, in Mild to Moderate Alzheimer Disease
-
Salloway, S.; Sperling, R.; Keren, R.; Porsteinsson, A. P.; van Dyck, C. H.; Tariot, P. N.; Gilman, S.; Arnold, D.; Abushakra, S.; Hernandez, C. A Phase 2 Randomized Trial of ELND005, scyllo-Inositol, in Mild to Moderate Alzheimer Disease Neurology 2011, 77, 1253-1262
-
(2011)
Neurology
, vol.77
, pp. 1253-1262
-
-
Salloway, S.1
Sperling, R.2
Keren, R.3
Porsteinsson, A.P.4
Van Dyck, C.H.5
Tariot, P.N.6
Gilman, S.7
Arnold, D.8
Abushakra, S.9
Hernandez, C.10
-
32
-
-
0032562547
-
Phosphatidylinositol and Inositol Involvement in Alzheimer Amyloid-β Fibril Growth and Arrest
-
McLaurin, J.; Franklin, T.; Chakrabartty, A.; Fraser, P. Phosphatidylinositol and Inositol Involvement in Alzheimer Amyloid-β Fibril Growth and Arrest J. Mol. Biol. 1998, 278, 183-194
-
(1998)
J. Mol. Biol.
, vol.278
, pp. 183-194
-
-
McLaurin, J.1
Franklin, T.2
Chakrabartty, A.3
Fraser, P.4
-
33
-
-
78649801398
-
Molecular Mechanism of β-sheet Self-organization at Water-Hydrophobic Interfaces
-
Nikolic, A.; Baud, S.; Rauscher, S.; Pomès, R. Molecular Mechanism of β-sheet Self-organization at Water-Hydrophobic Interfaces Proteins 2011, 79, 1-22
-
(2011)
Proteins
, vol.79
, pp. 1-22
-
-
Nikolic, A.1
Baud, S.2
Rauscher, S.3
Pomès, R.4
-
34
-
-
33846250450
-
Proline and Glycine Control Protein Self-Organization into Elastomeric or Amyloid Fibrils
-
Rauscher, S.; Baud, S.; Miao, M.; Keeley, F. W.; Pomès, R. Proline and Glycine Control Protein Self-Organization into Elastomeric or Amyloid Fibrils Structure 2006, 14, 1667-1676
-
(2006)
Structure
, vol.14
, pp. 1667-1676
-
-
Rauscher, S.1
Baud, S.2
Miao, M.3
Keeley, F.W.4
Pomès, R.5
-
35
-
-
84863022640
-
Binding of Inositol Stereoisomers to Model Amyloidogenic Peptides to Model Amyloidogenic Peptides
-
Li, G.; Rauscher, S.; Baud, S.; Pomès, R. Binding of Inositol Stereoisomers to Model Amyloidogenic Peptides to Model Amyloidogenic Peptides J. Phys. Chem. B 2012, 116, 1111-1119
-
(2012)
J. Phys. Chem. B
, vol.116
, pp. 1111-1119
-
-
Li, G.1
Rauscher, S.2
Baud, S.3
Pomès, R.4
-
36
-
-
77950618150
-
Molecular Simulations of Protein Disorder
-
Rauscher, S.; Pomès, R. Molecular Simulations of Protein Disorder Biochem. Cell. Biol. 2010, 88, 269-290
-
(2010)
Biochem. Cell. Biol.
, vol.88
, pp. 269-290
-
-
Rauscher, S.1
Pomès, R.2
-
37
-
-
78650863624
-
Atomic-Level Characterization of the Ensemble of the Aβ(1-42) Monomer in Water Using Unbiased Molecular Dynamics Simulations and Spectral Algorithms
-
Sgourakis, N. G.; Merced-Serrano, M.; Boutsidis, C.; Drineas, P.; Du, Z.; Wang, C.; Garciá, A. E. Atomic-Level Characterization of the Ensemble of the Aβ(1-42) Monomer in Water Using Unbiased Molecular Dynamics Simulations and Spectral Algorithms J. Mol. Biol. 2011, 405, 570-583
-
(2011)
J. Mol. Biol.
, vol.405
, pp. 570-583
-
-
Sgourakis, N.G.1
Merced-Serrano, M.2
Boutsidis, C.3
Drineas, P.4
Du, Z.5
Wang, C.6
Garciá, A.E.7
-
38
-
-
33645281939
-
Characterizing the Conformational Ensemble of Monomeric Polyglutamine
-
Wang, X.; Vitalis, A.; Wyczalkowski, M. A.; Pappu, R. V. Characterizing the Conformational Ensemble of Monomeric Polyglutamine Proteins 2005, 63, 297-311
-
(2005)
Proteins
, vol.63
, pp. 297-311
-
-
Wang, X.1
Vitalis, A.2
Wyczalkowski, M.A.3
Pappu, R.V.4
-
39
-
-
84859224210
-
Microsecond Molecular Dynamics Simulations of Intrinsically Disordered Proteins Involved in the Oxidative Stress Response
-
Cino, E. A.; Wong-ekkabut, J.; Karttunen, M.; Choy, W.-Y. Microsecond Molecular Dynamics Simulations of Intrinsically Disordered Proteins Involved in the Oxidative Stress Response PLoS One 2011, 6, e27371
-
(2011)
PLoS One
, vol.6
, pp. 27371
-
-
Cino, E.A.1
Wong-Ekkabut, J.2
Karttunen, M.3
Choy, W.-Y.4
-
40
-
-
77951912863
-
Destabilizing Alzheimer's Aβ42 Protofibrils with Morin: Mechanistic Insights from Molecular Dynamics Simulations
-
Lemkul, J.; Bevan, D. Destabilizing Alzheimer's Aβ42 Protofibrils with Morin: Mechanistic Insights from Molecular Dynamics Simulations Biochemistry 2010, 49, 3935-3946
-
(2010)
Biochemistry
, vol.49
, pp. 3935-3946
-
-
Lemkul, J.1
Bevan, D.2
-
41
-
-
77956307401
-
Thermodynamic Analysis of the Molecular Interactions between Amyloid β-Peptide 42 and (-)-Epigallocatechin-3-gallate
-
Wang, S.-H.; Liu, F.-F.; Dong, X.-Y.; Sun, Y. Thermodynamic Analysis of the Molecular Interactions Between Amyloid β-Peptide 42 and (-)-Epigallocatechin-3-gallate J. Phys. Chem. B 2010, 114, 11576-11583
-
(2010)
J. Phys. Chem. B
, vol.114
, pp. 11576-11583
-
-
Wang, S.-H.1
Liu, F.-F.2
Dong, X.-Y.3
Sun, Y.4
-
42
-
-
70350020364
-
Molecular Dynamics Simulations of Ibuprofen Binding to Aβ peptides
-
Raman, E. P.; Takeda, T.; Klimov, D. K. Molecular Dynamics Simulations of Ibuprofen Binding to Aβ peptides Biophys. J. 2009, 97, 2070-2079
-
(2009)
Biophys. J.
, vol.97
, pp. 2070-2079
-
-
Raman, E.P.1
Takeda, T.2
Klimov, D.K.3
-
43
-
-
77957959117
-
Binding of Nonsteroidal Antiinflammatory Drugs to Aβ Fibril
-
Takeda, T.; Chang, W. E.; Raman, E. P.; Klimov, D. K. Binding of Nonsteroidal Antiinflammatory Drugs to Aβ Fibril Proteins 2010, 78, 2849-2860
-
(2010)
Proteins
, vol.78
, pp. 2849-2860
-
-
Takeda, T.1
Chang, W.E.2
Raman, E.P.3
Klimov, D.K.4
-
44
-
-
84954358136
-
The Binding of Thioflavin T and Its Neutral Analog BTA-1 to Protofibrils of the Alzheimer's Disease Aβ16-22 Peptide Probed by Molecular Dynamics Simulations
-
Wu, C.; Wang, Z.; Lei, H.; Duan, Y.; Bowers, M. T.; Shea, J.-E. The Binding of Thioflavin T and Its Neutral Analog BTA-1 to Protofibrils of the Alzheimer's Disease Aβ16-22 Peptide Probed by Molecular Dynamics Simulations J. Mol. Biol. 2008, 384, 718-729
-
(2008)
J. Mol. Biol.
, vol.384
, pp. 718-729
-
-
Wu, C.1
Wang, Z.2
Lei, H.3
Duan, Y.4
Bowers, M.T.5
Shea, J.-E.6
-
45
-
-
79953839293
-
On the Origin of the Stronger Binding of PIB over Thioflavin T to Protofibrils of the Alzheimer Amyloid-β Peptide: A Molecular Dynamics Study
-
Wu, C.; Bowers, M.; Shea, J.-E. On the Origin of the Stronger Binding of PIB over Thioflavin T to Protofibrils of the Alzheimer Amyloid-β Peptide: A Molecular Dynamics Study Biophys. J. 2011, 100, 1316-1324
-
(2011)
Biophys. J.
, vol.100
, pp. 1316-1324
-
-
Wu, C.1
Bowers, M.2
Shea, J.-E.3
-
46
-
-
68549085272
-
Molecular Insight into the Inhibition Effect of Trehalose on the Nucleation and Elongation of Amyloid β-Peptide Oligomers
-
Liu, F.-F.; Ji, L.; Dong, X.-Y.; Sun, Y. Molecular Insight Into the Inhibition Effect of Trehalose on the Nucleation and Elongation of Amyloid β-Peptide Oligomers J. Phys. Chem. B 2009, 113, 11320-11329
-
(2009)
J. Phys. Chem. B
, vol.113
, pp. 11320-11329
-
-
Liu, F.-F.1
Ji, L.2
Dong, X.-Y.3
Sun, Y.4
-
47
-
-
44849087785
-
EGCG Redirects Amyloidogenic Polypeptides into Unstructured, Off-Pathway Oligomers
-
Ehrnhoefer, D. E.; Bieschke, J.; Boeddrich, A.; Herbst, M.; Masino, L.; Lurz, R.; Engemann, S.; Pastore, A.; Wanker, E. E. EGCG Redirects Amyloidogenic Polypeptides into Unstructured, Off-Pathway Oligomers Nat. Struct. Mol. Biol. 2008, 15, 558-566
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 558-566
-
-
Ehrnhoefer, D.E.1
Bieschke, J.2
Boeddrich, A.3
Herbst, M.4
Masino, L.5
Lurz, R.6
Engemann, S.7
Pastore, A.8
Wanker, E.E.9
-
48
-
-
78649285837
-
Interactions between Amyloidophilic Dyes and Their Relevance to Studies of Amyloid Inhibitors
-
Buell, A. K.; Dobson, C. M.; Knowles, T. P. J.; Welland, M. E. Interactions Between Amyloidophilic Dyes and Their Relevance to Studies of Amyloid Inhibitors Biophys. J. 2010, 99, 3492-3497
-
(2010)
Biophys. J.
, vol.99
, pp. 3492-3497
-
-
Buell, A.K.1
Dobson, C.M.2
Knowles, T.P.J.3
Welland, M.E.4
-
49
-
-
21244490033
-
Multiple Ligand Binding Sites on Aβ(1-40) Fibrils
-
LeVine, H. Multiple Ligand Binding Sites on Aβ(1-40) Fibrils Amyloid 2005, 12, 5-14
-
(2005)
Amyloid
, vol.12
, pp. 5-14
-
-
Levine, H.1
-
50
-
-
0029912748
-
Development and Testing of the OPLS All-Atom Force Field on Conformational Energetics and Properties of Organic Liquids
-
Jorgensen, W. L.; Maxwell, D. S.; Tirado-Rives, J. Development and Testing of the OPLS All-Atom Force Field on Conformational Energetics and Properties of Organic Liquids J. Am. Chem. Soc. 1996, 118, 11225-11236
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 11225-11236
-
-
Jorgensen, W.L.1
Maxwell, D.S.2
Tirado-Rives, J.3
-
51
-
-
0042296402
-
OPLS All-Atom Force Field for Carbohydrates
-
Damm, W.; Frontera, A.; Tirado-Rives, J.; Jorgensen, W. L. OPLS All-Atom Force Field for Carbohydrates J. Comput. Chem. 1997, 18, 1955-1970
-
(1997)
J. Comput. Chem.
, vol.18
, pp. 1955-1970
-
-
Damm, W.1
Frontera, A.2
Tirado-Rives, J.3
Jorgensen, W.L.4
-
52
-
-
0004016501
-
Comparison of Simple Potential Functions for Simulating Liquid Water
-
Jorgensen, W. L.; Chandrasekhar, J.; Madura, J. D.; Impey, R. W.; Klein, M. L. Comparison of Simple Potential Functions for Simulating Liquid Water J. Chem. Phys. 1983, 79, 926-935
-
(1983)
J. Chem. Phys.
, vol.79
, pp. 926-935
-
-
Jorgensen, W.L.1
Chandrasekhar, J.2
Madura, J.D.3
Impey, R.W.4
Klein, M.L.5
-
53
-
-
46249092554
-
Gromacs 4: Algorithms for Highly Efficient, Load- Balanced, and Scalable Molecular Simulation
-
Hess, B.; Kutzner, C.; van der Spoel, D. Gromacs 4: Algorithms for Highly Efficient, Load- Balanced, and Scalable Molecular Simulation J. Chem. Theory Comput. 2008, 4, 435-447
-
(2008)
J. Chem. Theory Comput.
, vol.4
, pp. 435-447
-
-
Hess, B.1
Kutzner, C.2
Van Der Spoel, D.3
-
54
-
-
27344454932
-
Gromacs: Fast, Flexible, and Free
-
Spoel, D. V. D.; Lindahl, E.; Hess, B.; Groenhof, G.; Mark, A. E.; Berendsen, H. J. C. Gromacs: Fast, Flexible, and Free J. Comput. Chem. 2005, 26, 1701-1718
-
(2005)
J. Comput. Chem.
, vol.26
, pp. 1701-1718
-
-
Spoel, D.V.D.1
Lindahl, E.2
Hess, B.3
Groenhof, G.4
Mark, A.E.5
Berendsen, H.J.C.6
-
55
-
-
33846823909
-
Particle Mesh Ewald: An N·Log(N) Method for Ewald Sums in Large Systems
-
Darden, T.; York, D.; Pedersen, L. Particle Mesh Ewald: An N·Log(N) Method for Ewald Sums in Large Systems J. Chem. Phys. 1993, 98, 10089-10092
-
(1993)
J. Chem. Phys.
, vol.98
, pp. 10089-10092
-
-
Darden, T.1
York, D.2
Pedersen, L.3
-
56
-
-
33750587438
-
Molecular Dynamics with Coupling to an External Bath
-
Berendsen, H. J. C.; Postma, J. P. M.; Gunsteren, W. F. V.; DiNola, A.; Haak, J. Molecular Dynamics with Coupling to an External Bath J. Chem. Phys. 1984, 81, 3684-3690
-
(1984)
J. Chem. Phys.
, vol.81
, pp. 3684-3690
-
-
Berendsen, H.J.C.1
Postma, J.P.M.2
Gunsteren, W.F.V.3
Dinola, A.4
Haak, J.5
-
57
-
-
33646940952
-
Numerical Integration of the Cartesian Equations of Motion of a System with Constraints: Molecular Dynamics of N-Alkanes
-
Ryckaert, J. P.; Ciccotti, G.; Berendsen, H. J. C. Numerical Integration of the Cartesian Equations of Motion of a System with Constraints: Molecular Dynamics of N-Alkanes J. Comput. Phys. 1977, 23, 327-341
-
(1977)
J. Comput. Phys.
, vol.23
, pp. 327-341
-
-
Ryckaert, J.P.1
Ciccotti, G.2
Berendsen, H.J.C.3
-
58
-
-
73949096788
-
Simulated Tempering Distributed Replica Sampling, Virtual Replica Exchange, and Other Generalized-Ensemble Methods for Conformational Sampling
-
Rauscher, S.; Neale, C.; Pomès, R. Simulated Tempering Distributed Replica Sampling, Virtual Replica Exchange, and Other Generalized-Ensemble Methods for Conformational Sampling J. Chem. Theory Comput. 2009, 5, 2640-2662
-
(2009)
J. Chem. Theory Comput.
, vol.5
, pp. 2640-2662
-
-
Rauscher, S.1
Neale, C.2
Pomès, R.3
-
59
-
-
33846202602
-
Distributed Replica Sampling
-
Rodinger, T.; Howell, P.; Pomès, R. Distributed Replica Sampling J. Chem. Theory Comput. 2006, 2, 725-731
-
(2006)
J. Chem. Theory Comput.
, vol.2
, pp. 725-731
-
-
Rodinger, T.1
Howell, P.2
Pomès, R.3
-
60
-
-
0020997912
-
Dictionary of Protein Secondary Structure: Pattern Recognition of Hydrogen-Bonded and Geometrical Features
-
Kabsch, W.; Sander, C. Dictionary of Protein Secondary Structure: Pattern Recognition of Hydrogen-Bonded and Geometrical Features Biopolymers 1983, 22, 2577-2637
-
(1983)
Biopolymers
, vol.22
, pp. 2577-2637
-
-
Kabsch, W.1
Sander, C.2
-
61
-
-
0029878720
-
VMD: Visual Molecular Dynamics
-
27-28
-
Humphrey, W.; Dalke, A.; Schulten, K. VMD: Visual Molecular Dynamics J. Mol. Graph. 1996, 14, 33-38, 27-28
-
(1996)
J. Mol. Graph.
, vol.14
, pp. 33-38
-
-
Humphrey, W.1
Dalke, A.2
Schulten, K.3
-
62
-
-
79953118623
-
Toward a Molecular Theory of Early and Late Events in Monomer to Amyloid Fibril Formation
-
Straub, J. E.; Thirumalai, D. Toward a Molecular Theory of Early and Late Events in Monomer to Amyloid Fibril Formation Annu. Rev. Phys. Chem. 2011, 62, 437-463
-
(2011)
Annu. Rev. Phys. Chem.
, vol.62
, pp. 437-463
-
-
Straub, J.E.1
Thirumalai, D.2
-
63
-
-
0026619343
-
Substitutions of Hydrophobic Amino Acids Reduce the Amyloidogenicity of Alzheimer's Disease βa4 Peptides
-
Hilbich, C.; Kisters-Woike, B.; Reed, J.; Masters, C. L.; Beyreuther, K. Substitutions of Hydrophobic Amino Acids Reduce the Amyloidogenicity of Alzheimer's Disease βA4 Peptides J. Mol. Biol. 1992, 228, 460-473
-
(1992)
J. Mol. Biol.
, vol.228
, pp. 460-473
-
-
Hilbich, C.1
Kisters-Woike, B.2
Reed, J.3
Masters, C.L.4
Beyreuther, K.5
-
64
-
-
0035902507
-
Inhibition of β-Amyloid(40) Fibrillogenesis and Disassembly of β-Amyloid(40) Fibrils by Short β-Amyloid Congeners Containing N-Methyl Amino Acids at Alternate Residues
-
Gordon, D. J.; Sciarretta, K. L.; Meredith, S. C. Inhibition of β-Amyloid(40) Fibrillogenesis and Disassembly of β-Amyloid(40) Fibrils by Short β-Amyloid Congeners Containing N-Methyl Amino Acids at Alternate Residues Biochemistry 2001, 40, 8237-8245
-
(2001)
Biochemistry
, vol.40
, pp. 8237-8245
-
-
Gordon, D.J.1
Sciarretta, K.L.2
Meredith, S.C.3
-
65
-
-
0036289548
-
Inhibitors of Fibril Formation and Cytotoxicity of β-Amyloid Peptide Composed of KLVFF Recognition Element and Flexible Hydrophilic Disrupting Element
-
Watanabe, K.-i.; Nakamura, K.; Akikusa, S.; Okada, T.; Kodaka, M.; Konakahara, T.; Okuno, H. Inhibitors of Fibril Formation and Cytotoxicity of β-Amyloid Peptide Composed of KLVFF Recognition Element and Flexible Hydrophilic Disrupting Element Biochem. Biophys. Res. Commun. 2002, 290, 121-124
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.290
, pp. 121-124
-
-
Watanabe, K.-I.1
Nakamura, K.2
Akikusa, S.3
Okada, T.4
Kodaka, M.5
Konakahara, T.6
Okuno, H.7
-
66
-
-
0027411230
-
Structure of β-Crystallite Assemblies Formed by Alzheimer Beta-Amyloid Protein Analogues: Analysis by X-Ray Diffraction
-
Inouye, H.; Fraser, P. E.; Kirschner, D. A. Structure of β-Crystallite Assemblies Formed by Alzheimer Beta-Amyloid Protein Analogues: Analysis by X-Ray Diffraction Biophys. J. 1993, 64, 502-519
-
(1993)
Biophys. J.
, vol.64
, pp. 502-519
-
-
Inouye, H.1
Fraser, P.E.2
Kirschner, D.A.3
-
67
-
-
66149140617
-
Seeded Growth of β-amyloid Fibrils from Alzheimer's Brain-derived Fibrils Produces a Distinct Fibril Structure
-
Paravastu, A. K.; Qahwash, I.; Leapman, R. D.; Meredith, S. C.; Tycko, R. Seeded Growth of β-amyloid Fibrils from Alzheimer's Brain-derived Fibrils Produces a Distinct Fibril Structure Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 7443-7448
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 7443-7448
-
-
Paravastu, A.K.1
Qahwash, I.2
Leapman, R.D.3
Meredith, S.C.4
Tycko, R.5
-
68
-
-
84871285635
-
Role of Aromatic Side Chains in Amyloid β-Protein Aggregation
-
Cukalevski, R.; Boland, B.; Frohm, B.; Thulin, E.; Walsh, D.; Linse, S. Role of Aromatic Side Chains in Amyloid β-Protein Aggregation ACS Chem. Neurosci. 2012, 3, 1008-1016
-
(2012)
ACS Chem. Neurosci.
, vol.3
, pp. 1008-1016
-
-
Cukalevski, R.1
Boland, B.2
Frohm, B.3
Thulin, E.4
Walsh, D.5
Linse, S.6
-
69
-
-
33644940173
-
Mutagenesis of the Central Hydrophobic Cluster in Aβ42 Alzheimer's Peptide. Side-Chain Properties Correlate with Aggregation Propensities
-
de Groot, N. S.; Aviles, F. X.; Vendrell, J.; Ventura, S. Mutagenesis of the Central Hydrophobic Cluster in Aβ42 Alzheimer's Peptide. Side-Chain Properties Correlate with Aggregation Propensities FEBS J. 2006, 273, 658-668
-
(2006)
FEBS J.
, vol.273
, pp. 658-668
-
-
De Groot, N.S.1
Aviles, F.X.2
Vendrell, J.3
Ventura, S.4
-
70
-
-
28444442999
-
3D Structure of Alzheimer's Amyloid-β(1-42) Fibrils
-
Lührs, T.; Ritter, C.; Adrian, M.; Riek-Loher, D.; Bohrmann, B.; Döbeli, H.; Schubert, D.; Riek, R. 3D Structure of Alzheimer's Amyloid-β(1-42) Fibrils Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 17342-17347
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 17342-17347
-
-
Lührs, T.1
Ritter, C.2
Adrian, M.3
Riek-Loher, D.4
Bohrmann, B.5
Döbeli, H.6
Schubert, D.7
Riek, R.8
-
71
-
-
77950825396
-
Molecular Structures of Quiescently Grown and Brain- Derived Polymorphic Fibrils of the Alzheimer Amyloid Aβ(9-40) Peptide: A Comparison to Agitated Fibrils
-
Wu, C.; Bowers, M. T.; Shea, J.-E. Molecular Structures of Quiescently Grown and Brain- Derived Polymorphic Fibrils of the Alzheimer Amyloid Aβ(9-40) Peptide: A Comparison to Agitated Fibrils PLoS Comput. Biol. 2010, 6, e1000693
-
(2010)
PLoS Comput. Biol.
, vol.6
-
-
Wu, C.1
Bowers, M.T.2
Shea, J.-E.3
-
72
-
-
84864695671
-
Binding of Congo Red to Amyloid Protofibrils of the Alzheimer Aβ9-40 Peptide Probed by Molecular Dynamics Simulations
-
Wu, C.; Scott, J.; Shea, J.-E. Binding of Congo Red to Amyloid Protofibrils of the Alzheimer Aβ9-40 Peptide Probed by Molecular Dynamics Simulations Biophys. J. 2012, 103, 550-557
-
(2012)
Biophys. J.
, vol.103
, pp. 550-557
-
-
Wu, C.1
Scott, J.2
Shea, J.-E.3
-
73
-
-
33846781516
-
Dual Binding Modes of Congo Red to Amyloid Protofibril Surface Observed in Molecular Dynamics Simulations
-
Wu, C.; Wang, Z.; Lei, H.; Zhang, W.; Duan, Y. Dual Binding Modes of Congo Red to Amyloid Protofibril Surface Observed in Molecular Dynamics Simulations J. Am. Chem. Soc. 2007, 129, 1225-1232
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 1225-1232
-
-
Wu, C.1
Wang, Z.2
Lei, H.3
Zhang, W.4
Duan, Y.5
-
74
-
-
48449084725
-
Synthesis of scyllo-Inositol Derivatives and Their Effects on Amyloid β Peptide Aggregation
-
Sun, Y.; Zhang, G.; Hawkes, C.; Shaw, J.; McLaurin, J.; Nitz, M. Synthesis of scyllo-Inositol Derivatives and Their Effects on Amyloid β Peptide Aggregation Bioorg. Med. Chem. 2008, 16, 7177-7184
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 7177-7184
-
-
Sun, Y.1
Zhang, G.2
Hawkes, C.3
Shaw, J.4
McLaurin, J.5
Nitz, M.6
-
75
-
-
33745096194
-
Inhibition of Amyloid Fibril Formation by Polyphenols: Structural Similarity and Aromatic Interactions as a Common Inhibition Mechanism
-
Porat, Y.; Abramowitz, A.; Gazit, E. Inhibition of Amyloid Fibril Formation by Polyphenols: Structural Similarity and Aromatic Interactions as a Common Inhibition Mechanism Chem. Biol. Drug Des. 2006, 67, 27-37
-
(2006)
Chem. Biol. Drug Des.
, vol.67
, pp. 27-37
-
-
Porat, Y.1
Abramowitz, A.2
Gazit, E.3
-
76
-
-
0034057552
-
Analysis and Prediction of Carbohydrate Binding Sites
-
Taroni, C.; Jones, S.; Thornton, J. M. Analysis and Prediction of Carbohydrate Binding Sites Protein Eng. 2000, 13, 89-98
-
(2000)
Protein Eng.
, vol.13
, pp. 89-98
-
-
Taroni, C.1
Jones, S.2
Thornton, J.M.3
-
77
-
-
78049282418
-
Free Energy Surfaces for the Interaction of D-Glucose with Planar Aromatic Groups in Aqueous Solution
-
Wohlert, J.; Schnupf, U.; Brady, J. W. Free Energy Surfaces for the Interaction of D-Glucose with Planar Aromatic Groups in Aqueous Solution J. Chem. Phys. 2010, 133, 155103-155111
-
(2010)
J. Chem. Phys.
, vol.133
, pp. 155103-155111
-
-
Wohlert, J.1
Schnupf, U.2
Brady, J.W.3
-
78
-
-
77953981103
-
Pulling a Single Polymer Molecule off a Substrate Reveals the Binding Thermodynamics of Cosolutes
-
Geisler, M.; Netz, R.; Hugel, T. Pulling a Single Polymer Molecule Off a Substrate Reveals the Binding Thermodynamics of Cosolutes Angew. Chem., Int. Ed. 2010, 49, 4730-4733
-
(2010)
Angew. Chem., Int. Ed.
, vol.49
, pp. 4730-4733
-
-
Geisler, M.1
Netz, R.2
Hugel, T.3
-
79
-
-
0034951022
-
The Structural Basis for Carbohydrate Recognition by Lectins
-
Sharon, N.; Lis, H. The Structural Basis for Carbohydrate Recognition by Lectins Adv. Exp. Med. Biol. 2001, 491, 1-16
-
(2001)
Adv. Exp. Med. Biol.
, vol.491
, pp. 1-16
-
-
Sharon, N.1
Lis, H.2
-
80
-
-
34948866227
-
Evaluation of a Carbohydrate-π Interaction in a Peptide Model System
-
Kiehna, S. E.; Laughrey, Z. R.; Waters, M. L. Evaluation of a Carbohydrate-π Interaction in a Peptide Model System Chem. Commun. 2007, 4026-4028
-
(2007)
Chem. Commun.
, pp. 4026-4028
-
-
Kiehna, S.E.1
Laughrey, Z.R.2
Waters, M.L.3
-
81
-
-
70349501722
-
InCa-SiteFinder: A Method for Structurebased Prediction of Inositol and Carbohydrate Binding Sites on Proteins
-
Kulharia, M.; Bridgett, S.; Goody, R.; Jackson, R. InCa-SiteFinder: A Method for Structurebased Prediction of Inositol and Carbohydrate Binding Sites on Proteins J. Mol. Graph. 2009, 28, 297-303
-
(2009)
J. Mol. Graph.
, vol.28
, pp. 297-303
-
-
Kulharia, M.1
Bridgett, S.2
Goody, R.3
Jackson, R.4
-
82
-
-
0029952519
-
Structural Basis of Lectin-Carbohydrate Recognition
-
Weis, W. I.; Drickamer, K. Structural Basis of Lectin-Carbohydrate Recognition Annu. Rev. Biochem. 1996, 65, 441-473
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 441-473
-
-
Weis, W.I.1
Drickamer, K.2
-
83
-
-
0000358206
-
Carbohydrate-Protein Interactions: Basis of Glycobiology
-
Lee, Y. C.; Lee, R. T. Carbohydrate-Protein Interactions: Basis of Glycobiology Acc. Chem. Res. 1995, 28, 321-327
-
(1995)
Acc. Chem. Res.
, vol.28
, pp. 321-327
-
-
Lee, Y.C.1
Lee, R.T.2
-
84
-
-
84991718926
-
-
Methods and Principles in Medicinal Chemistry; Jahnke, W. Erlanson, D. Mannhold, R. Kubinyi, H. Folkers, G. Wiley-VCH Verlag GmbH & Co. KGaA: Weinheim, Germany
-
Krishnamurthy, V. M.; Estroff, L. A.; Whitesides, G. M. In Fragment-Based Approaches in Drug Discovery; Methods and Principles in Medicinal Chemistry; Jahnke, W.; Erlanson, D.; Mannhold, R.; Kubinyi, H.; Folkers, G., Eds.; Wiley-VCH Verlag GmbH & Co. KGaA: Weinheim, Germany, 2006; pp 11-19.
-
(2006)
Fragment-Based Approaches in Drug Discovery
, pp. 11-19
-
-
Krishnamurthy, V.M.1
Estroff, L.A.2
Whitesides, G.M.3
|