Seeded growth of β-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 18, 2009, Pages 7443-7448

  Paravastu, Anant K ^a,d   Qahwash, Isam ^b   Leapman, Richard D ^c   Meredith, Stephen C ^b   Tycko, Robert ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

^d FAMU FSU COLLEGE OF ENGINEERING   (United States)

Author keywords

Alzheimer's disease; Electron microscopy; Solid state nuclear magnetic resonance

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; THIOFLAVINE; PEPTIDE FRAGMENT;

ADULT; AGED; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; BRAIN; BRAIN TISSUE; CARBON NUCLEAR MAGNETIC RESONANCE; CASE REPORT; CHEMICAL STRUCTURE; COGNITIVE DEFECT; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; FLUORESCENCE MICROSCOPY; GENETIC HETEROGENEITY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; MALE; NERVE DEGENERATION; NERVE FIBER; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID STATE; CHEMISTRY; METABOLISM; TRANSMISSION ELECTRON MICROSCOPY;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN; BRAIN; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS;

EID: 66149140617     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0812033106     Document Type: Article

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