Natural polyphenols as inhibitors of amyloid aggregation. Molecular dynamics study of GNNQQNY heptapeptide decamer

Biophysical Chemistry

Volumn 149, Issue 1-2, 2010, Pages 12-21

  Berhanu, Workalemahu M ^a   Masunov, Artëm E ^a  

^a UNIVERSITY OF CENTRAL FLORIDA   (United States)

Author keywords

sheet; Aggregation; Amyloid fibril; Beta sheet inhibitor; Hydrogen bond; Molecular dynamic simulation; Myricetin; Oligomer; Prion disease

Indexed keywords

AMYLOID PROTEIN; ASPARAGINE; GLUTAMINE; GLYCINE; HEPTAPEPTIDE; HYDROGEN; KAEMPFEROL; MYRICETIN; OLIGOMER; POLYPHENOL DERIVATIVE; PRION PROTEIN; TYROSINE;

ARTICLE; BETA SHEET; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; DRUG STRUCTURE; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; AMYLOID; FLAVONOIDS; HYDROGEN BONDING; KAEMPFEROLS; MOLECULAR DYNAMICS SIMULATION; OLIGOPEPTIDES; PHENOLS; PRIONS; PROTEIN STRUCTURE, SECONDARY; TIME FACTORS;

EID: 77952674128     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2010.03.003     Document Type: Article

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