Mutagenesis of the central hydrophobic cluster in Aβ42 Alzheimer's peptide: Side-chain properties correlate with aggregation propensities

FEBS Journal

Volumn 273, Issue 3, 2006, Pages 658-668

  De Groot, Natalia Sánchez ^a   Aviles, Francesc X ^a   Vendrell, Josep ^a   Ventura, Salvador ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Alzheimer's disease; Escherichia coli; Green fluorescent protein; Protein aggregation; Protein misfolding

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42];

ALZHEIMER DISEASE; ARTICLE; CORRELATION ANALYSIS; DISEASE ACTIVITY; ESCHERICHIA COLI; GENE MUTATION; GENE OVEREXPRESSION; HYDROPHOBICITY; MUTAGENESIS; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN AGGREGATION; SUBSTITUTION REACTION;

AMYLOID BETA-PROTEIN; CELL LINE; CIRCULAR DICHROISM; ESCHERICHIA COLI; GREEN FLUORESCENT PROTEINS; HUMANS; HYDROPHOBICITY; MICROSCOPY, ELECTRON; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; SPECTROMETRY, FLUORESCENCE; THIAZOLES;

ESCHERICHIA COLI;

EID: 33644940173     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2005.05102.x     Document Type: Article

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