-
1
-
-
0000075190
-
The catalytic hydrogenation of polyhydric phenols. I. The synthesis of meso-inositol, scyllitol and a new isomeric cyclitol
-
Anderson C., Wallis E.S.J. The catalytic hydrogenation of polyhydric phenols. I. The synthesis of meso-inositol, scyllitol and a new isomeric cyclitol. American Chemical Society 1948, 70:2931-2935.
-
(1948)
American Chemical Society
, vol.70
, pp. 2931-2935
-
-
Anderson, C.1
Wallis, E.S.J.2
-
2
-
-
0000862598
-
Cyclitols. III. Some tosyl esters of inositols. Synthesis of a new inositol
-
Angyal S.J., Matheson N.K. Cyclitols. III. Some tosyl esters of inositols. Synthesis of a new inositol. Journal of American Chemical Society 1955, 77:4343-4346.
-
(1955)
Journal of American Chemical Society
, vol.77
, pp. 4343-4346
-
-
Angyal, S.J.1
Matheson, N.K.2
-
4
-
-
84891742850
-
-
Aytan N., Carreras I., Choi J.-K., Kowall N.W., Jenkins B.G., Dedeoglu A. Effects of scyllo-inositol in a novel transgenic model of Alzheimer's disease 2011, http://www.sfn.org/am2011/index.aspx%3fpagename%3dfinal_program.
-
(2011)
Effects of scyllo-inositol in a novel transgenic model of Alzheimer's disease
-
-
Aytan, N.1
Carreras, I.2
Choi, J.-K.3
Kowall, N.W.4
Jenkins, B.G.5
Dedeoglu, A.6
-
5
-
-
0022420493
-
Natural plant chemicals: Sources of industrial and medicinal materials
-
Balandrin M.F., Klocke J.A., Wurtele E.S., Bollinger W.H. Natural plant chemicals: Sources of industrial and medicinal materials. Science 1985, 228:1154-1160.
-
(1985)
Science
, vol.228
, pp. 1154-1160
-
-
Balandrin, M.F.1
Klocke, J.A.2
Wurtele, E.S.3
Bollinger, W.H.4
-
6
-
-
45549095784
-
Polyphenols as potential inhibitors of amyloid aggregation and toxicity: Possible significance to Alzheimer's disease
-
Bastianetto S., Krantic S., Quirion R. Polyphenols as potential inhibitors of amyloid aggregation and toxicity: Possible significance to Alzheimer's disease. Mini Reviews in Medicinal Chemistry 2008, 8:429-435.
-
(2008)
Mini Reviews in Medicinal Chemistry
, vol.8
, pp. 429-435
-
-
Bastianetto, S.1
Krantic, S.2
Quirion, R.3
-
9
-
-
4444383266
-
Expression of the sodium-myo-inositol cotransporter SMIT2 at the apical membrane of Madin-Darby canine kidney cells
-
Bissonnette P., Coady M.J., Lapoi J. Expression of the sodium-myo-inositol cotransporter SMIT2 at the apical membrane of Madin-Darby canine kidney cells. Journal of Physiology 2004, 558:759-768.
-
(2004)
Journal of Physiology
, vol.558
, pp. 759-768
-
-
Bissonnette, P.1
Coady, M.J.2
Lapoi, J.3
-
11
-
-
0005555638
-
De l'isomérie optique dans les corps a' chaines fermées
-
Bouveault L. De l'isomérie optique dans les corps a' chaines fermées. Bulletin de la Societe Chimique de Paris 1894, 11:144-147.
-
(1894)
Bulletin de la Societe Chimique de Paris
, vol.11
, pp. 144-147
-
-
Bouveault, L.1
-
12
-
-
0014094570
-
Occurrence and metabolism of scyllo-inositol in the locust
-
Candy D.J. Occurrence and metabolism of scyllo-inositol in the locust. Biochemical Journal 1967, 103:666-671.
-
(1967)
Biochemical Journal
, vol.103
, pp. 666-671
-
-
Candy, D.J.1
-
13
-
-
84891742978
-
United States Patent Application Publication: Methods of treatment of hyperuricemia and associated disease states
-
application number 12/560,113US 2010/0152305 A1
-
Cedarbaum J.M. United States Patent Application Publication: Methods of treatment of hyperuricemia and associated disease states. Elan Pharmaceuticals 2009, application number 12/560,113US 2010/0152305 A1. http://www.google.com/patents/.
-
(2009)
Elan Pharmaceuticals
-
-
Cedarbaum, J.M.1
-
14
-
-
0035877756
-
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695
-
Chishti M.A., Yang D., Janus C., Phinney A.L., Horne P., Pearson J., et al. Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. Journal of Biological Chemistry 2001, 276:21562-21570.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 21562-21570
-
-
Chishti, M.A.1
Yang, D.2
Janus, C.3
Phinney, A.L.4
Horne, P.5
Pearson, J.6
-
15
-
-
77956259428
-
Detection of increased scyllo-inositol in brain with magnetic resonance spectroscopy after dietary supplementation in Alzheimers disease mouse models
-
Choi J.-K., Carreras I., Dedeoglu A., Jenkins B.G. Detection of increased scyllo-inositol in brain with magnetic resonance spectroscopy after dietary supplementation in Alzheimers disease mouse models. Neuropharmacology 2010, 59:353-357.
-
(2010)
Neuropharmacology
, vol.59
, pp. 353-357
-
-
Choi, J.-K.1
Carreras, I.2
Dedeoglu, A.3
Jenkins, B.G.4
-
16
-
-
0033516880
-
Practical synthesis of all inositol stereoisomers from myo-inositol
-
Chung S.K., Kwon Y.U. Practical synthesis of all inositol stereoisomers from myo-inositol. Bioorganic & Medicinal Chemistry Letters 1999, 9:2135-2140.
-
(1999)
Bioorganic & Medicinal Chemistry Letters
, vol.9
, pp. 2135-2140
-
-
Chung, S.K.1
Kwon, Y.U.2
-
20
-
-
77749328953
-
-
Key={081F7976-E4CD-4F3D-A0AF-E8387992A658}
-
DaSilva K.A., Brown M.E., Cousins J.E., Rappaport R.V., Aubert I., Westaway D., et al. scyllo-Inositol (ELND005) ameliorates amyloid pathology in an aggressive mouse model of Alzheimer's disease 2009, Key={081F7976-E4CD-4F3D-A0AF-E8387992A658}. http://www.abstractsonline.com/Plan/ViewAbstract.aspx%3F.
-
(2009)
scyllo-Inositol (ELND005) ameliorates amyloid pathology in an aggressive mouse model of Alzheimer's disease
-
-
DaSilva, K.A.1
Brown, M.E.2
Cousins, J.E.3
Rappaport, R.V.4
Aubert, I.5
Westaway, D.6
-
21
-
-
77955528206
-
Pittsburgh compound B (11C-PIB) and fluorodeoxyglucose (18 F-FDG) PET in patients with Alzheimer disease, mild cognitive impairment, and healthy controls
-
Devanand D.P., Mikhno A., Pelton G.H., Cuasay K., Pradhaban G., Dileep Kumar J.S., et al. Pittsburgh compound B (11C-PIB) and fluorodeoxyglucose (18 F-FDG) PET in patients with Alzheimer disease, mild cognitive impairment, and healthy controls. Journal of Geriatric Psychiatry Neurology 2010, 23:185-198.
-
(2010)
Journal of Geriatric Psychiatry Neurology
, vol.23
, pp. 185-198
-
-
Devanand, D.P.1
Mikhno, A.2
Pelton, G.H.3
Cuasay, K.4
Pradhaban, G.5
Dileep Kumar, J.S.6
-
23
-
-
84868131332
-
Pentylenetetrazol (PTZ) kindling model of epilepsy
-
Dihr A. Pentylenetetrazol (PTZ) kindling model of epilepsy. Currunt Protocol in Neuroscience 2012, 58:9.37.1-9.37.12.
-
(2012)
Currunt Protocol in Neuroscience
, vol.58
-
-
Dihr, A.1
-
24
-
-
84891740114
-
-
November 29, 2011, Elan Corporation Press Release
-
Elan Corporation Press Release Elan Provides an Update on ELND005 (scyllo-inositol) 2011, November 29, 2011. http://newsroom.elan.com/phoenix.zhtml%3fc%3d88326%26p%3dirol-newsArticle%26ID%3d1634478%26highlight%3d.
-
(2011)
Elan Provides an Update on ELND005 (scyllo-inositol)
-
-
-
25
-
-
84891741224
-
Synthesis and evaluation of a series of scyllo-inositol/2-(fluoroethyl)-8-methyl-2,8-diazaspirol[4,5]decane-1,3-dione combined derivatives as potential amyloid-beta polymerization inhibitors and PET oligomer-Abeta probes
-
Elmaleh D., Shoup T., Fu H., Johnson K., Selkoe D., Fischman A. Synthesis and evaluation of a series of scyllo-inositol/2-(fluoroethyl)-8-methyl-2,8-diazaspirol[4,5]decane-1,3-dione combined derivatives as potential amyloid-beta polymerization inhibitors and PET oligomer-Abeta probes. Journal of Nuclear Medicine 2010, 51:1497.
-
(2010)
Journal of Nuclear Medicine
, vol.51
, pp. 1497
-
-
Elmaleh, D.1
Shoup, T.2
Fu, H.3
Johnson, K.4
Selkoe, D.5
Fischman, A.6
-
26
-
-
71249124418
-
Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation
-
Feng Y., Wang X.P., Yang S.G., Wang Y.J., Zhang X., Du X.T., et al. Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation. Neurotoxicology 2009, 30:986-995.
-
(2009)
Neurotoxicology
, vol.30
, pp. 986-995
-
-
Feng, Y.1
Wang, X.P.2
Yang, S.G.3
Wang, Y.J.4
Zhang, X.5
Du, X.T.6
-
27
-
-
34249867410
-
Properties of scyllo-inositol as a therapeutic treatment of AD-like pathology
-
Fenili D., Brown M., Rappaport R., McLaurin J. Properties of scyllo-inositol as a therapeutic treatment of AD-like pathology. Journal of Molecular Medicine (Berliner) 2007, 85:603-611.
-
(2007)
Journal of Molecular Medicine (Berliner)
, vol.85
, pp. 603-611
-
-
Fenili, D.1
Brown, M.2
Rappaport, R.3
McLaurin, J.4
-
28
-
-
84864320049
-
Scyllo-Inositol: A potential therapeutic for Alzheimer's disease
-
Royal Society of Chemistry, England, A. Martinez (Ed.)
-
Fenili D., Ma K., McLaurin J. scyllo-Inositol: A potential therapeutic for Alzheimer's disease. Emerging Drugs and Targets for Alzheimer's Disease 2010, 1:94-116). Royal Society of Chemistry, England. A. Martinez (Ed.).
-
(2010)
Emerging Drugs and Targets for Alzheimer's Disease
, vol.1
, pp. 94-116
-
-
Fenili, D.1
Ma, K.2
McLaurin, J.3
-
29
-
-
80052059432
-
Sodium/myo-Inositol transporters: substrate transport requirments and regional brain expression in the TgCRND8 mouse model of amyloid pathology
-
e24032
-
Fenili D., Weng Y.-Q., Aubert I., Nitz M., McLaurin J. Sodium/myo-Inositol transporters: substrate transport requirments and regional brain expression in the TgCRND8 mouse model of amyloid pathology. PLoS One 2011, 6. e24032.
-
(2011)
PLoS One
, vol.6
-
-
Fenili, D.1
Weng, Y.-Q.2
Aubert, I.3
Nitz, M.4
McLaurin, J.5
-
30
-
-
27144541627
-
Controlling β-amyloid oligomerization by the use of naphthalene sulfonates
-
Ferrão-Gonzales A.D., Robbs B.K., Moreau V.H., Ferreira A., Juliano L., Valente A.P., et al. Controlling β-amyloid oligomerization by the use of naphthalene sulfonates. Journal of Biological Chemistry 2005, 280:34747-34754.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 34747-34754
-
-
Ferrão-Gonzales, A.D.1
Robbs, B.K.2
Moreau, V.H.3
Ferreira, A.4
Juliano, L.5
Valente, A.P.6
-
31
-
-
0036677944
-
Inositol and higher inositol phosphates in neural tissues: Homeostasis, metabolism and functional significance
-
Fisher S.K., Novak J.E., Agranoff B.W. Inositol and higher inositol phosphates in neural tissues: Homeostasis, metabolism and functional significance. Journal of Neuroscience 2002, 82:736-754.
-
(2002)
Journal of Neuroscience
, vol.82
, pp. 736-754
-
-
Fisher, S.K.1
Novak, J.E.2
Agranoff, B.W.3
-
32
-
-
18144415471
-
Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease
-
Fox N.C., Black R.S., Gilman S., et al. Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease. Neurology 2005, 10:1563-1572.
-
(2005)
Neurology
, vol.10
, pp. 1563-1572
-
-
Fox, N.C.1
Black, R.S.2
Gilman, S.3
-
33
-
-
77953515555
-
Oral amyloid anit-aggregation agent ELND005 is measurable in CSF and brain of healthy adult men
-
Garzone P., Koller M., Pastrak A., Jhee S.S., Ereshefsky L., Moran S., et al. Oral amyloid anit-aggregation agent ELND005 is measurable in CSF and brain of healthy adult men. Alzheimer's and Dementia 2009, 5(Suppl):323.
-
(2009)
Alzheimer's and Dementia
, vol.5
, Issue.SUPPL.
, pp. 323
-
-
Garzone, P.1
Koller, M.2
Pastrak, A.3
Jhee, S.S.4
Ereshefsky, L.5
Moran, S.6
-
35
-
-
0028946739
-
Kinetics and specificity of the renal Na+/myo-inositol cotransporter expressed in Xenopus oocytes
-
Hager K., Hazama A., Kwon H.M., Loo D.D., Handler J.S., Wright E.M. Kinetics and specificity of the renal Na+/myo-inositol cotransporter expressed in Xenopus oocytes. Journal of Membrane Biology 1995, 143:103-113.
-
(1995)
Journal of Membrane Biology
, vol.143
, pp. 103-113
-
-
Hager, K.1
Hazama, A.2
Kwon, H.M.3
Loo, D.D.4
Handler, J.S.5
Wright, E.M.6
-
36
-
-
78650485059
-
Scyllitol from flowering dogwood (Cornus florida)
-
Hann R.M., Sando C.E. Scyllitol from flowering dogwood (Cornus florida). Journal of Biological Chemistry 1926, 68:399-402.
-
(1926)
Journal of Biological Chemistry
, vol.68
, pp. 399-402
-
-
Hann, R.M.1
Sando, C.E.2
-
37
-
-
0032496763
-
Active transport properties of porcine choroid plexus cells in culture
-
Hakvoort A., Haselbach M., Galla H. Active transport properties of porcine choroid plexus cells in culture. Brain Research 1998, 795:247-256.
-
(1998)
Brain Research
, vol.795
, pp. 247-256
-
-
Hakvoort, A.1
Haselbach, M.2
Galla, H.3
-
38
-
-
74549169940
-
Small molecule beta-amyloid inhibitors that stabilize protofibrillar structures in vitro improve cognition and pathology in a mouse model of Alzheimer's disease
-
Hawkes C.A., Deng L.H., Shaw J.E., Nitz M., McLaurin J. Small molecule beta-amyloid inhibitors that stabilize protofibrillar structures in vitro improve cognition and pathology in a mouse model of Alzheimer's disease. European Journal of Neuroscience 2010, 31:203-213.
-
(2010)
European Journal of Neuroscience
, vol.31
, pp. 203-213
-
-
Hawkes, C.A.1
Deng, L.H.2
Shaw, J.E.3
Nitz, M.4
McLaurin, J.5
-
39
-
-
84864318278
-
In vivo uptake of β-amyloid by non-plaque associated microglia
-
[BSP/CAR/E-Pub/00096]
-
Hawkes C.A., Deng L., Fenili D., Nitz M., McLaurin J. In vivo uptake of β-amyloid by non-plaque associated microglia. Current Alzheimer Research 2012, [BSP/CAR/E-Pub/00096].
-
(2012)
Current Alzheimer Research
-
-
Hawkes, C.A.1
Deng, L.2
Fenili, D.3
Nitz, M.4
McLaurin, J.5
-
40
-
-
0017389874
-
Interconversion of myo- and scyllo-inositol with simultaneous formation of neo-inositol by an NADP+ dependent epimerase from bovine brain
-
Hipps P.P., Holland W.H., Sherman W.R. Interconversion of myo- and scyllo-inositol with simultaneous formation of neo-inositol by an NADP+ dependent epimerase from bovine brain. Biochemical and Biophysical Research Communications 1977, 77:340-346.
-
(1977)
Biochemical and Biophysical Research Communications
, vol.77
, pp. 340-346
-
-
Hipps, P.P.1
Holland, W.H.2
Sherman, W.R.3
-
41
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
Holcomb L., Gordon M.N., McGowan E., Yu X., Benkovic S., Jantzen P., et al. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nature Medicine 1998, 4:97-100.
-
(1998)
Nature Medicine
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
-
42
-
-
0022462840
-
Metabolism and function of myo-inositol and inositol phospholipids
-
Holub B.J. Metabolism and function of myo-inositol and inositol phospholipids. Annual Review of Nutrition 1986, 6:563-597.
-
(1986)
Annual Review of Nutrition
, vol.6
, pp. 563-597
-
-
Holub, B.J.1
-
43
-
-
0029947940
-
Cellular localization of Na+/myo-inositol co-transporter mRNA in the rat brain
-
Inoue K., Shimada Y., Minami H., Morimura A., Miyai A., Yamauchi A., et al. Cellular localization of Na+/myo-inositol co-transporter mRNA in the rat brain. Neuroreport 1996, 7:1195-1198.
-
(1996)
Neuroreport
, vol.7
, pp. 1195-1198
-
-
Inoue, K.1
Shimada, Y.2
Minami, H.3
Morimura, A.4
Miyai, A.5
Yamauchi, A.6
-
44
-
-
0033568120
-
Effect of osmolality and anion channel inhibitors on myo-inositol efflux in cultured astrocytes
-
Isaacks R.E., Bender A.S., Kim C.Y., Shi Y.F., Norenberg M.D. Effect of osmolality and anion channel inhibitors on myo-inositol efflux in cultured astrocytes. Journal of Neuroscience Research 1999, 57:866-871.
-
(1999)
Journal of Neuroscience Research
, vol.57
, pp. 866-871
-
-
Isaacks, R.E.1
Bender, A.S.2
Kim, C.Y.3
Shi, Y.F.4
Norenberg, M.D.5
-
45
-
-
33746917562
-
Absence of synaptophysin near cortical neurons containing oligomer Aβ in Alzheimer's disease brain
-
Ishibashi K.-I., Tomiyama T., Nishitsuji K., Hara M., Mori H. Absence of synaptophysin near cortical neurons containing oligomer Aβ in Alzheimer's disease brain. Journal of Neuroscience Research 2006, 84:632-636.
-
(2006)
Journal of Neuroscience Research
, vol.84
, pp. 632-636
-
-
Ishibashi, K.-I.1
Tomiyama, T.2
Nishitsuji, K.3
Hara, M.4
Mori, H.5
-
46
-
-
0034700471
-
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
Janus C., Pearson J., McLaurin J., Mathews P.M., Jiang Y., Schmidt S.D., et al. A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 2000, 408:979-982.
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
-
47
-
-
79960036957
-
H+/myo-inositol transporter genes, hmit-1.1 and hmit-1.2, have roles in the osmoprotective response in Caenorhabditis elegans
-
Kage-Nakadai E., Uehara T., Mitani S. H+/myo-inositol transporter genes, hmit-1.1 and hmit-1.2, have roles in the osmoprotective response in Caenorhabditis elegans. Biochemical and Biophysical Research Communications 2011, 410:471-477.
-
(2011)
Biochemical and Biophysical Research Communications
, vol.410
, pp. 471-477
-
-
Kage-Nakadai, E.1
Uehara, T.2
Mitani, S.3
-
48
-
-
80052266213
-
The amyloid cascade hypothesis for Alzheimer's disease: An appraisal for the development of therapeutics
-
Karran E., Mercken M., De Strooper B. The amyloid cascade hypothesis for Alzheimer's disease: An appraisal for the development of therapeutics. Nature Reviews Drug Discovery 2011, 10:698-712.
-
(2011)
Nature Reviews Drug Discovery
, vol.10
, pp. 698-712
-
-
Karran, E.1
Mercken, M.2
De Strooper, B.3
-
49
-
-
24744472049
-
Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease
-
Kelly B.L., Vassar R., Ferreira A. Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease. Journal of Biological Chemistry 2005, 280(36):31746-31753.
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.36
, pp. 31746-31753
-
-
Kelly, B.L.1
Vassar, R.2
Ferreira, A.3
-
50
-
-
21044453723
-
Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo
-
Klyubin I., Walsh D.M., Lemere C.A., Cullen W.K., Shankar G.M., Betts V., et al. Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo. Nature Medicine 2005, 11:556-561.
-
(2005)
Nature Medicine
, vol.11
, pp. 556-561
-
-
Klyubin, I.1
Walsh, D.M.2
Lemere, C.A.3
Cullen, W.K.4
Shankar, G.M.5
Betts, V.6
-
51
-
-
33747484171
-
N-Methylated peptide inhibitors of beta-amyloid aggregation and toxicity. Optimization of the inhibitor structure
-
Kokkoni N., Stott K., Amijee H., Mason J.M., Doig A.J. N-Methylated peptide inhibitors of beta-amyloid aggregation and toxicity. Optimization of the inhibitor structure. Biochemistry 2006, 45:9906-9918.
-
(2006)
Biochemistry
, vol.45
, pp. 9906-9918
-
-
Kokkoni, N.1
Stott, K.2
Amijee, H.3
Mason, J.M.4
Doig, A.J.5
-
52
-
-
19444371852
-
Oligomeric proteins ultrastructurally localize to cell processes, especially to axon terminals with higher density, but not to lipid rafts in Tg2576 mouse brain
-
Kokubo H., Kayed R., Glabe C.G., Saido T.C., Iwata N., Helms J.B., et al. Oligomeric proteins ultrastructurally localize to cell processes, especially to axon terminals with higher density, but not to lipid rafts in Tg2576 mouse brain. Brain Research 2005, 1045:224-228.
-
(2005)
Brain Research
, vol.1045
, pp. 224-228
-
-
Kokubo, H.1
Kayed, R.2
Glabe, C.G.3
Saido, T.C.4
Iwata, N.5
Helms, J.B.6
-
53
-
-
0015921235
-
Total stereoselective synthesis of myo-, allo-, neo-, and epi-inositols
-
Kowarski C., Sarel S.J. Total stereoselective synthesis of myo-, allo-, neo-, and epi-inositols. Journal of Organic Chemistry 1973, 38:117-119.
-
(1973)
Journal of Organic Chemistry
, vol.38
, pp. 117-119
-
-
Kowarski, C.1
Sarel, S.J.2
-
54
-
-
0026673965
-
Cloning of the cDNa for a Na+/myo-inositol cotransporter: A hypertonicity stress protein
-
Kwon H.M., Yamauchi A., Uchida S., Preston A.S., Garcia-Perez A., Burg M.B., et al. Cloning of the cDNa for a Na+/myo-inositol cotransporter: A hypertonicity stress protein. Journal of Biological Chemistry 1992, 267:6297-6301.
-
(1992)
Journal of Biological Chemistry
, vol.267
, pp. 6297-6301
-
-
Kwon, H.M.1
Yamauchi, A.2
Uchida, S.3
Preston, A.S.4
Garcia-Perez, A.5
Burg, M.B.6
-
55
-
-
20844458090
-
Synaptic targeting by Alzheimer's-related amyloid beta oligomers
-
Lacor P.N., Buniel M.C., Chang L., Fernandez S.J., Gong Y., Viola K.L., et al. Synaptic targeting by Alzheimer's-related amyloid beta oligomers. Journal of Neuroscience 2004, 24:10191-10200.
-
(2004)
Journal of Neuroscience
, vol.24
, pp. 10191-10200
-
-
Lacor, P.N.1
Buniel, M.C.2
Chang, L.3
Fernandez, S.J.4
Gong, Y.5
Viola, K.L.6
-
56
-
-
0008675162
-
Inositol dehydrogenase from aerobacter aerogenes
-
Larner J., Jackson W.T., Graves D.J., Stamer J.R. Inositol dehydrogenase from aerobacter aerogenes. Archives of Biochemistry and Biophysics 1956, 60:352-363.
-
(1956)
Archives of Biochemistry and Biophysics
, vol.60
, pp. 352-363
-
-
Larner, J.1
Jackson, W.T.2
Graves, D.J.3
Stamer, J.R.4
-
57
-
-
84891747571
-
Population pharmacokinetic analysis of plasma, cerebrospinal fluid and brain ELND005 in patients with mild to moderate Alzheimer's disease
-
Liang E., Cedarbaum J., Abushakra S., Green M., Yan L., Wagg J. Population pharmacokinetic analysis of plasma, cerebrospinal fluid and brain ELND005 in patients with mild to moderate Alzheimer's disease. Alzheimer's and Dementia 2009, 5(Suppl):465.
-
(2009)
Alzheimer's and Dementia
, vol.5
, Issue.SUPPL.
, pp. 465
-
-
Liang, E.1
Cedarbaum, J.2
Abushakra, S.3
Green, M.4
Yan, L.5
Wagg, J.6
-
58
-
-
58049097210
-
Human sodium/inositol cotransporter 2 (SMIT2) transports inositols but not glucose in L6 cells
-
Lin X., Ma L., Fitzgerald R.L., Ostlund R.E. Human sodium/inositol cotransporter 2 (SMIT2) transports inositols but not glucose in L6 cells. Archives of Biochemistry and Biophysics 2009, 481:197-201.
-
(2009)
Archives of Biochemistry and Biophysics
, vol.481
, pp. 197-201
-
-
Lin, X.1
Ma, L.2
Fitzgerald, R.L.3
Ostlund, R.E.4
-
59
-
-
0141953293
-
Activation of muscarinic cholinergic receptors enhances the volume-sensitive efflux of myo-inositol from SH-SY5Y neuroblastoma cells
-
Loveday D., Heacock A.M., Fisher S.K. Activation of muscarinic cholinergic receptors enhances the volume-sensitive efflux of myo-inositol from SH-SY5Y neuroblastoma cells. Journal of Neurochemistry 2003, 87:476-486.
-
(2003)
Journal of Neurochemistry
, vol.87
, pp. 476-486
-
-
Loveday, D.1
Heacock, A.M.2
Fisher, S.K.3
-
60
-
-
37049081749
-
General synthesis of inositols by hydrolysis of conduritol epoxides obtained biocatalytically from halogenobenzenes: (+)-D-chiro-inositol, allo-inositol, muco-inositol and neo-inositol
-
Mandel M., Hudlicky T.J. General synthesis of inositols by hydrolysis of conduritol epoxides obtained biocatalytically from halogenobenzenes: (+)-D-chiro-inositol, allo-inositol, muco-inositol and neo-inositol. Journal of the Chemical Society. Perkin Transaction 1993, 1:741-743.
-
(1993)
Journal of the Chemical Society. Perkin Transaction
, vol.1
, pp. 741-743
-
-
Mandel, M.1
Hudlicky, T.J.2
-
61
-
-
0031733739
-
Effect of extracellular pH on the myo-inositol transporter SMIT expressed in Xenopus oocytes
-
Matskevitch J., Wagner C.A., Risler T., Kwon H.M., Handler J.S., Waldegger S., et al. Effect of extracellular pH on the myo-inositol transporter SMIT expressed in Xenopus oocytes. Pflugers Archive 1998, 436:854-857.
-
(1998)
Pflugers Archive
, vol.436
, pp. 854-857
-
-
Matskevitch, J.1
Wagner, C.A.2
Risler, T.3
Kwon, H.M.4
Handler, J.S.5
Waldegger, S.6
-
62
-
-
80053586691
-
Comparisons of [18F]-1-deoxy-1-fluoro-scyllo-inositol with [18F]-FDG for PET imaging of inflammation, breast and brain cancer xenografts in athymic mice
-
McLarty K., Moran M.D., Scollard D.A., Chan C., Sabha N., Mukherjee J., et al. Comparisons of [18F]-1-deoxy-1-fluoro-scyllo-inositol with [18F]-FDG for PET imaging of inflammation, breast and brain cancer xenografts in athymic mice. Nuclear Medicine Biology 2011, 38:953-959.
-
(2011)
Nuclear Medicine Biology
, vol.38
, pp. 953-959
-
-
McLarty, K.1
Moran, M.D.2
Scollard, D.A.3
Chan, C.4
Sabha, N.5
Mukherjee, J.6
-
63
-
-
0029861772
-
Membrane disruption by Alzheimer β-amyloid peptides mediated through specific binding to either phospholipids or gangliosides
-
McLaurin J., Chakrabartty A. Membrane disruption by Alzheimer β-amyloid peptides mediated through specific binding to either phospholipids or gangliosides. Journal of Biological Chemistry 1996, 271:26482-26489.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 26482-26489
-
-
McLaurin, J.1
Chakrabartty, A.2
-
64
-
-
0030892291
-
Characterization of the interactions of Alzheimer β-amyloid peptides with phospholipid membranes
-
McLaurin J., Chakrabartty A. Characterization of the interactions of Alzheimer β-amyloid peptides with phospholipid membranes. European Journal of Biochemistry 1997, 245:355-363.
-
(1997)
European Journal of Biochemistry
, vol.245
, pp. 355-363
-
-
McLaurin, J.1
Chakrabartty, A.2
-
65
-
-
0032562547
-
Phosphatidylinositol and inositol involvement in Alzheimer amyloid-β fibril growth and arrest
-
McLaurin J., Franklin T., Chakrabartty A., Fraser P.E. Phosphatidylinositol and inositol involvement in Alzheimer amyloid-β fibril growth and arrest. Journal of Molecular Biology 1998, 278:183-194.
-
(1998)
Journal of Molecular Biology
, vol.278
, pp. 183-194
-
-
McLaurin, J.1
Franklin, T.2
Chakrabartty, A.3
Fraser, P.E.4
-
66
-
-
0034674785
-
Inositol stereoisomers stabilize an oligomeric aggregate of Alzheimer amyloid β peptide and inhibit Aβ-induced toxicity
-
McLaurin J., Golomb R., Jurewiczi A., Anteli J.P., Fraser P.E. Inositol stereoisomers stabilize an oligomeric aggregate of Alzheimer amyloid β peptide and inhibit Aβ-induced toxicity. Journal of Biological Chemistry 2000, 275:18495-18502.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 18495-18502
-
-
McLaurin, J.1
Golomb, R.2
Jurewiczi, A.3
Anteli, J.P.4
Fraser, P.E.5
-
67
-
-
33745922350
-
Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model
-
McLaurin J., Kierstead M.E., Brown M.E., Hawkes C.A., Lambermon M.H., Phinney A.L., et al. Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model. Nature Medicine 2006, 12:801-808.
-
(2006)
Nature Medicine
, vol.12
, pp. 801-808
-
-
McLaurin, J.1
Kierstead, M.E.2
Brown, M.E.3
Hawkes, C.A.4
Lambermon, M.H.5
Phinney, A.L.6
-
68
-
-
68949151731
-
Reproductive characteristics and population decline of four species of skate (Rajidae) off the eastern coast of Canada
-
McPhie R.P., Campana S.E. Reproductive characteristics and population decline of four species of skate (Rajidae) off the eastern coast of Canada. Journal of Fish Biology 2009, 75:233-246.
-
(2009)
Journal of Fish Biology
, vol.75
, pp. 233-246
-
-
McPhie, R.P.1
Campana, S.E.2
-
69
-
-
0034021656
-
Murine chromosome 16 telomeric region, homologous with human chromosome 21q22, contains the osmoregulatory Na(+)/myo-inositol cotransporter (SLC5A3) gene
-
McVeigh K.E., Mallee J.J., Lucente A., Barnoski B.L., Wu S., Berry G.T. Murine chromosome 16 telomeric region, homologous with human chromosome 21q22, contains the osmoregulatory Na(+)/myo-inositol cotransporter (SLC5A3) gene. Cytogenetics and Cell Genetics 2000, 88:153-158.
-
(2000)
Cytogenetics and Cell Genetics
, vol.88
, pp. 153-158
-
-
McVeigh, K.E.1
Mallee, J.J.2
Lucente, A.3
Barnoski, B.L.4
Wu, S.5
Berry, G.T.6
-
71
-
-
37049151522
-
Cocositol (cocosite), a constituent of the leaves of "Cocos nucifera" and "cocos plumosa"
-
Müller H. Cocositol (cocosite), a constituent of the leaves of "Cocos nucifera" and "cocos plumosa" Journal of the Chemical Society Transactions 1907, 91:1767-1780.
-
(1907)
Journal of the Chemical Society Transactions
, vol.91
, pp. 1767-1780
-
-
Müller, H.1
-
73
-
-
34848848499
-
Fluorine in pharmaceuticals: looking beyond intuition
-
Müller K., Faeh C., Diederich F. Fluorine in pharmaceuticals: looking beyond intuition. Science 2007, 317:1881-1886.
-
(2007)
Science
, vol.317
, pp. 1881-1886
-
-
Müller, K.1
Faeh, C.2
Diederich, F.3
-
74
-
-
0033932696
-
Regulation of myo-inositol homeostasis in differentiated human NT2-N neurons
-
Novak J.E., Agranoff B.W., Fisher S.K. Regulation of myo-inositol homeostasis in differentiated human NT2-N neurons. Neurochemical Research 2000, 25(5):561-566.
-
(2000)
Neurochemical Research
, vol.25
, Issue.5
, pp. 561-566
-
-
Novak, J.E.1
Agranoff, B.W.2
Fisher, S.K.3
-
75
-
-
79551604692
-
Anticonvulsant activities of myo-inositol and scyllo-inositol on pentylenetetrazol induced seizures
-
Nozadze M., Mikautadze E., Lepsveridze E., Mikeladze E., Kuchiashvili N., Kiguradze T., et al. Anticonvulsant activities of myo-inositol and scyllo-inositol on pentylenetetrazol induced seizures. Seizure 2011, 20:173-176.
-
(2011)
Seizure
, vol.20
, pp. 173-176
-
-
Nozadze, M.1
Mikautadze, E.2
Lepsveridze, E.3
Mikeladze, E.4
Kuchiashvili, N.5
Kiguradze, T.6
-
76
-
-
33749521100
-
Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: Potential factors in amyloid plaque formation
-
Oakley H., Cole S.L., Logan S., Maus E., Shao P., Craft J., et al. Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: Potential factors in amyloid plaque formation. Journal of Neuroscience 2006, 26:10129-10140.
-
(2006)
Journal of Neuroscience
, vol.26
, pp. 10129-10140
-
-
Oakley, H.1
Cole, S.L.2
Logan, S.3
Maus, E.4
Shao, P.5
Craft, J.6
-
77
-
-
0344845132
-
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease
-
Oddo S., Caccamo A., Kitazawa M., Tseng B.P., LaFerla F.M. Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiology of Aging 2003, 24:1063-1070.
-
(2003)
Neurobiology of Aging
, vol.24
, pp. 1063-1070
-
-
Oddo, S.1
Caccamo, A.2
Kitazawa, M.3
Tseng, B.P.4
LaFerla, F.M.5
-
78
-
-
0029962370
-
A stereospecific myo-inositol/D-chiro-inositol transporter in HepG2 liver cells. Identification with D-chiro-[3-3H]inositol
-
Ostlund R.E., Seemayer R., Gupta S., Kimmel R., Ostlund E.L., Sherman W.R. A stereospecific myo-inositol/D-chiro-inositol transporter in HepG2 liver cells. Identification with D-chiro-[3-3H]inositol. Journal of Biological Chemistry 1996, 271:10073-10078.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 10073-10078
-
-
Ostlund, R.E.1
Seemayer, R.2
Gupta, S.3
Kimmel, R.4
Ostlund, E.L.5
Sherman, W.R.6
-
79
-
-
84891735661
-
Radiosynthesis of 2-[18F]fluoro-2-deoxy-scyllo-inositol for PET imaging of phosphadtidylinositol pool in PI3 kinase activity
-
Pal A., Mukhapadhyay U., Volgin A., Shavrin A., Tong W., Gelovani J., Alauddin M. Radiosynthesis of 2-[18F]fluoro-2-deoxy-scyllo-inositol for PET imaging of phosphadtidylinositol pool in PI3 kinase activity. Journal of Nuclear Medicine 2009, 50:261.
-
(2009)
Journal of Nuclear Medicine
, vol.50
, pp. 261
-
-
Pal, A.1
Mukhapadhyay, U.2
Volgin, A.3
Shavrin, A.4
Tong, W.5
Gelovani, J.6
Alauddin, M.7
-
80
-
-
81455128231
-
Development and validation of a yeast high-throughput screen for inhibitors of Aβ42 oligomerization
-
Park S., Pegan S.D., Mesecar A.D., Jungbauer L.M., LaDu M.J., Liebman S.W. Development and validation of a yeast high-throughput screen for inhibitors of Aβ42 oligomerization. Disease Models & Mechanisms 2011, 4:822-831.
-
(2011)
Disease Models & Mechanisms
, vol.4
, pp. 822-831
-
-
Park, S.1
Pegan, S.D.2
Mesecar, A.D.3
Jungbauer, L.M.4
LaDu, M.J.5
Liebman, S.W.6
-
81
-
-
0038181194
-
Stereoselective synthesis of myo-, neo-, L-chiro, D-chiro, allo-, scyllo-, and epi-inositol systems via conduritols prepared from p-benzoquinon
-
Podeschwa M., Plettenburg O., vom Brocke J., Block O., Adelt S., Altenbach H.-J. Stereoselective synthesis of myo-, neo-, L-chiro, D-chiro, allo-, scyllo-, and epi-inositol systems via conduritols prepared from p-benzoquinon. European Journal of Organic Chemistry 2003, 2003:1958-1972.
-
(2003)
European Journal of Organic Chemistry
, vol.2003
, pp. 1958-1972
-
-
Podeschwa, M.1
Plettenburg, O.2
vom Brocke, J.3
Block, O.4
Adelt, S.5
Altenbach, H.-J.6
-
82
-
-
84891736524
-
Les Cyclitols
-
Posternak T. Les Cyclitols. Hermann 1965, 97.
-
(1965)
Hermann
, vol.97
-
-
Posternak, T.1
-
83
-
-
0035864884
-
Convenient synthesis of 4,6-di-O-benzyl-myo-inositol and myo-inositol 1,3,5-orthoesters
-
Praveen T., Shashidhar M.S. Convenient synthesis of 4,6-di-O-benzyl-myo-inositol and myo-inositol 1,3,5-orthoesters. Carbohydrate Research 2001, 330:409-411.
-
(2001)
Carbohydrate Research
, vol.330
, pp. 409-411
-
-
Praveen, T.1
Shashidhar, M.S.2
-
85
-
-
84891741313
-
ELD005 (scyllo-inositol), the β-amyloid anti-aggregation therapeutic, demonstrates robust brain uptake in rats following oral administration
-
Quinn K., Brigham B., Soriano F., Connop B., Sauer J.M. ELD005 (scyllo-inositol), the β-amyloid anti-aggregation therapeutic, demonstrates robust brain uptake in rats following oral administration. Alzheimer's and Dementia 2009, 5(Suppl):437.
-
(2009)
Alzheimer's and Dementia
, vol.5
, Issue.SUPPL.
, pp. 437
-
-
Quinn, K.1
Brigham, B.2
Soriano, F.3
Connop, B.4
Sauer, J.M.5
-
86
-
-
0018719504
-
Purification and properties of Bacillus subtilis inositol dehydrogenase
-
Ramaley R., Fujita Y., Freese E. Purification and properties of Bacillus subtilis inositol dehydrogenase. Journal of Biological Chemistry 1979, 254:7684-7690.
-
(1979)
Journal of Biological Chemistry
, vol.254
, pp. 7684-7690
-
-
Ramaley, R.1
Fujita, Y.2
Freese, E.3
-
87
-
-
84891735214
-
(United States patent application: Process for the preparation of scyllo-inositol)
-
20110201060
-
Reddy R.E., Chemburkar S.R., Spaulding D.R., Pan Y., Cao L., Restituyo J.A., et al. (United States patent application: Process for the preparation of scyllo-inositol). United States patent application number 2011, 20110201060. http://patents.com/us-20110201060.html.
-
(2011)
United States patent application number
-
-
Reddy, R.E.1
Chemburkar, S.R.2
Spaulding, D.R.3
Pan, Y.4
Cao, L.5
Restituyo, J.A.6
-
88
-
-
77949300796
-
11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending dose study
-
Rinne J.O., Brooks D.J., Rossor M.N., et al. 11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending dose study. Lancet Neurology 2010, 9:363-372.
-
(2010)
Lancet Neurology
, vol.9
, pp. 363-372
-
-
Rinne, J.O.1
Brooks, D.J.2
Rossor, M.N.3
-
89
-
-
0037138392
-
New human sodium/glucose cotransporter gene (KST1): Identification, characterization, and mutation analysis in ICCA (infantile convulsions and choreoathetosis) and BFIC (benign familial infantile convulsions) families
-
Roll P., Massacrier A., Pereira S., Robaglia-Schlupp A., Cau P., Szepetowski P. New human sodium/glucose cotransporter gene (KST1): Identification, characterization, and mutation analysis in ICCA (infantile convulsions and choreoathetosis) and BFIC (benign familial infantile convulsions) families. Gene 2002, 285:141-148.
-
(2002)
Gene
, vol.285
, pp. 141-148
-
-
Roll, P.1
Massacrier, A.2
Pereira, S.3
Robaglia-Schlupp, A.4
Cau, P.5
Szepetowski, P.6
-
90
-
-
82255179817
-
A phase 2 randomized trial of ELND005, scyllo-inositol, in mild to moderate Alzheimer disease
-
Salloway S., Sperling R., Keren R., Porsteinsson A.P., van Dyck C.H., Tariot P.N., et al. A phase 2 randomized trial of ELND005, scyllo-inositol, in mild to moderate Alzheimer disease. Neurology 2011, 77:1253-1262.
-
(2011)
Neurology
, vol.77
, pp. 1253-1262
-
-
Salloway, S.1
Sperling, R.2
Keren, R.3
Porsteinsson, A.P.4
van Dyck, C.H.5
Tariot, P.N.6
-
91
-
-
2442533108
-
Inositols and carbohydrates in different fresh fruit juices
-
Sanz M.L., Villamiel M., Martinez-Castro I. Inositols and carbohydrates in different fresh fruit juices. Food Chemistry 2004, 87:325-328.
-
(2004)
Food Chemistry
, vol.87
, pp. 325-328
-
-
Sanz, M.L.1
Villamiel, M.2
Martinez-Castro, I.3
-
92
-
-
0037461164
-
Sulfonate protecting groups. Improved synthesis of scyllo-inositol and its orthoformate from myo-inositol
-
Sarmah M.P., Shashidhar M.S. Sulfonate protecting groups. Improved synthesis of scyllo-inositol and its orthoformate from myo-inositol. Carbohydrate Research 2003, 338:999-1001.
-
(2003)
Carbohydrate Research
, vol.338
, pp. 999-1001
-
-
Sarmah, M.P.1
Shashidhar, M.S.2
-
93
-
-
0031911264
-
Identification of a high concentration of scyllo-inositol in the brain of a healthy human subject using 1H- and 13C-NMR
-
Seaquist E.R., Gruetter R. Identification of a high concentration of scyllo-inositol in the brain of a healthy human subject using 1H- and 13C-NMR. Magnetic Resonance in Medicine 1998, 39:313-316.
-
(1998)
Magnetic Resonance in Medicine
, vol.39
, pp. 313-316
-
-
Seaquist, E.R.1
Gruetter, R.2
-
94
-
-
34247137244
-
Behavioural phenotyping of sodium-myo-inositol cotransporter heterozygous knockout mice with reduced brain inositol
-
Shaldubina A., Buccafusca R., Johanson R.A., Agam G., Belmaker R.H., Berry G.T., Bersuds Y. Behavioural phenotyping of sodium-myo-inositol cotransporter heterozygous knockout mice with reduced brain inositol. Genes Brain Behavior 2007, 6(3):253-259.
-
(2007)
Genes Brain Behavior
, vol.6
, Issue.3
, pp. 253-259
-
-
Shaldubina, A.1
Buccafusca, R.2
Johanson, R.A.3
Agam, G.4
Belmaker, R.H.5
Berry, G.T.6
Bersuds, Y.7
-
95
-
-
33947314641
-
Natural oligomers of the Alzheimer amyloid-β protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
-
Shankar G.M., Bloodgood B.L., Townsend M., Walsh D.M., Selkoe D.J., Sabatini B.L. Natural oligomers of the Alzheimer amyloid-β protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. Journal of Neuroscience 2007, 27(11):2866-2875.
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.11
, pp. 2866-2875
-
-
Shankar, G.M.1
Bloodgood, B.L.2
Townsend, M.3
Walsh, D.M.4
Selkoe, D.J.5
Sabatini, B.L.6
-
96
-
-
84858790492
-
Assembly in the presence of scyllo-inositol derivatives: Identification of an oxime linkage as important for the development of assembly inhibitors
-
Shaw J.E., Chio J., Dasgupta S., Lai A.Y., Mo G.C.H., F.Pang F., et al. Assembly in the presence of scyllo-inositol derivatives: Identification of an oxime linkage as important for the development of assembly inhibitors. ACS Chemical Neuroscience 2011, 1-42. http://dx.doi.org/10.1021/cn2000926.
-
(2011)
ACS Chemical Neuroscience
, pp. 1-42
-
-
Shaw, J.E.1
Chio, J.2
Dasgupta, S.3
Lai, A.Y.4
Mo, G.C.H.5
F.Pang, F.6
-
97
-
-
0014288646
-
The measurement of myo-inositol, myo-inosose-2 and scyllo-inositol in mammalian tissues
-
Sherman W.R., Stewart M.A., Kurien M.M., Goodwin S.L. The measurement of myo-inositol, myo-inosose-2 and scyllo-inositol in mammalian tissues. Biochemica et Biophysica Acta 1968, 158:197-205.
-
(1968)
Biochemica et Biophysica Acta
, vol.158
, pp. 197-205
-
-
Sherman, W.R.1
Stewart, M.A.2
Kurien, M.M.3
Goodwin, S.L.4
-
99
-
-
79960469583
-
Biomarkers predicting Alzheimer's disease in cognitively normal aging
-
Shim Y.S., Morris J.C. Biomarkers predicting Alzheimer's disease in cognitively normal aging. Journal of Clinical Neurology 2011, 7:60-68.
-
(2011)
Journal of Clinical Neurology
, vol.7
, pp. 60-68
-
-
Shim, Y.S.1
Morris, J.C.2
-
100
-
-
84891739531
-
Synthesis and biodistribution of F-18 labeled scyllo-inositol derivatives as potential probes for decting amyloid beta oligomers
-
Shoup T., Elmaleh D., Carter E., Winter D., Tolman C., Fischman A. Synthesis and biodistribution of F-18 labeled scyllo-inositol derivatives as potential probes for decting amyloid beta oligomers. Journal of Nuclear Medicine 2009, 50:1935.
-
(2009)
Journal of Nuclear Medicine
, vol.50
, pp. 1935
-
-
Shoup, T.1
Elmaleh, D.2
Carter, E.3
Winter, D.4
Tolman, C.5
Fischman, A.6
-
101
-
-
58749105624
-
Determination of minor carbohydrates in carrot (Daucus carota L.) by GC-MS
-
Soria A.C., Sanz M.L., Villamiel M. Determination of minor carbohydrates in carrot (Daucus carota L.) by GC-MS. Food Chemistry 2009, 114:758-762.
-
(2009)
Food Chemistry
, vol.114
, pp. 758-762
-
-
Soria, A.C.1
Sanz, M.L.2
Villamiel, M.3
-
102
-
-
0017185480
-
The specificity and sulfhydryl sensitivity of the inositol transport system of the central nervous system
-
Spector R. The specificity and sulfhydryl sensitivity of the inositol transport system of the central nervous system. Journal of Neurochemistry 1976, 27:229-236.
-
(1976)
Journal of Neurochemistry
, vol.27
, pp. 229-236
-
-
Spector, R.1
-
103
-
-
48449084725
-
Synthesis of scyllo-inositol derivatives and their effects on amyloid beta peptide aggregation
-
Sun Y., Zhang G., Hawkes C.A., Shaw J.E., McLaurin J., Nitz M. Synthesis of scyllo-inositol derivatives and their effects on amyloid beta peptide aggregation. Bioorganic & Medicinal Chemistry 2008, 16:7177-7184.
-
(2008)
Bioorganic & Medicinal Chemistry
, vol.16
, pp. 7177-7184
-
-
Sun, Y.1
Zhang, G.2
Hawkes, C.A.3
Shaw, J.E.4
McLaurin, J.5
Nitz, M.6
-
104
-
-
0025191110
-
Glycosyl-inositol derivatives. I. Synthesis of 1-substituted chiro-inositol derivatives
-
Tagliaferri F., Wang S.-N., Berlin W.K., Outten R.A., Shen T.Y. Glycosyl-inositol derivatives. I. Synthesis of 1-substituted chiro-inositol derivatives. Tetrahedron Letters 1990, 31:1105-1108.
-
(1990)
Tetrahedron Letters
, vol.31
, pp. 1105-1108
-
-
Tagliaferri, F.1
Wang, S.-N.2
Berlin, W.K.3
Outten, R.A.4
Shen, T.Y.5
-
105
-
-
0035917329
-
Novel synthesis of enantiomerically pure natural inositols and their diastereoisomers
-
Takahashi H., Kittaka H., Ikegami S. Novel synthesis of enantiomerically pure natural inositols and their diastereoisomers. Journal of Organic Chemistry 2001, 66:2705-2716.
-
(2001)
Journal of Organic Chemistry
, vol.66
, pp. 2705-2716
-
-
Takahashi, H.1
Kittaka, H.2
Ikegami, S.3
-
106
-
-
33846003098
-
Orally available compound prevents deficits in memory caused by the Alzheimer amyloid-beta oligomers
-
Townsend M., Cleary J.P., Mehta T., Hofmeister J., Lesne S., O'Hare E., et al. Orally available compound prevents deficits in memory caused by the Alzheimer amyloid-beta oligomers. Annals of Neurology 2006, 60:668-676.
-
(2006)
Annals of Neurology
, vol.60
, pp. 668-676
-
-
Townsend, M.1
Cleary, J.P.2
Mehta, T.3
Hofmeister, J.4
Lesne, S.5
O'Hare, E.6
-
108
-
-
1442264822
-
+ /myo-inositol symporter at synapses and growth cones
-
+ /myo-inositol symporter at synapses and growth cones. EMBO Journal 2004, 23:531-540.
-
(2004)
EMBO Journal
, vol.23
, pp. 531-540
-
-
Uldry, M.1
Steiner, P.2
Zurich, M.3
Béguin, P.4
Hirling, H.5
Dolci, W.6
Thorens, B.7
-
109
-
-
70349275349
-
Synthesis and preliminary biological evaluations of [18F]-1-deoxy-1-fluoro-scyllo-inositol
-
Vasdev N., Chio J., van Oosten E.M., Nitz M., McLaurin J., Vines D.C., et al. Synthesis and preliminary biological evaluations of [18F]-1-deoxy-1-fluoro-scyllo-inositol. Chemical Communications (Cambridge) 2009, 37:5527-5529.
-
(2009)
Chemical Communications (Cambridge)
, vol.37
, pp. 5527-5529
-
-
Vasdev, N.1
Chio, J.2
van Oosten, E.M.3
Nitz, M.4
McLaurin, J.5
Vines, D.C.6
-
110
-
-
65549102934
-
Inducible over-expression of wild type α-synuclein in human neuronal cells leads to caspase-dependent non-apoptotic death
-
Vekrellis K., Xilouri M., Emmanouilidou E., Stefanis L. Inducible over-expression of wild type α-synuclein in human neuronal cells leads to caspase-dependent non-apoptotic death. Journal of Neurochemistry 2009, 109:1348-1362.
-
(2009)
Journal of Neurochemistry
, vol.109
, pp. 1348-1362
-
-
Vekrellis, K.1
Xilouri, M.2
Emmanouilidou, E.3
Stefanis, L.4
-
111
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh D.M., Klyubin I., Fadeeva J.V., Cullen W.K., Anwyl R., Wolfe M.S., et al. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 2002, 416:535-539.
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
-
112
-
-
0002578475
-
Synthesis of optically active inositol derivatives starting from D-glucurono-6,3-lactone
-
Watanabe Y., Mitani M., Ozaki S. Synthesis of optically active inositol derivatives starting from D-glucurono-6,3-lactone. Chemistry Letters 1987, 123-126.
-
(1987)
Chemistry Letters
, pp. 123-126
-
-
Watanabe, Y.1
Mitani, M.2
Ozaki, S.3
-
113
-
-
77955122149
-
Absolute quantification in proton magnetic resonance spectroscopy is useful to differentiate amnesic mild cognitive impairment from Alzheimer's disease and healthy aging
-
Watanabe T., Shiino A., Akiguchi I. Absolute quantification in proton magnetic resonance spectroscopy is useful to differentiate amnesic mild cognitive impairment from Alzheimer's disease and healthy aging. Dementia and Geriatric Cognitive Disorders 2010, 30:71-77.
-
(2010)
Dementia and Geriatric Cognitive Disorders
, vol.30
, pp. 71-77
-
-
Watanabe, T.1
Shiino, A.2
Akiguchi, I.3
-
114
-
-
79959892263
-
The reproductive cycle of the roundel skate Raja texana
-
Williams L.J., Cicia A.M., Pellegrin G.B., Smith K.M., Sulikowski J.A. The reproductive cycle of the roundel skate Raja texana. Journal of Fish Biology 2011, 79:298-305.
-
(2011)
Journal of Fish Biology
, vol.79
, pp. 298-305
-
-
Williams, L.J.1
Cicia, A.M.2
Pellegrin, G.B.3
Smith, K.M.4
Sulikowski, J.A.5
-
115
-
-
84891738886
-
-
Patent number US7745671
-
Yamaguchi M., Kita Y., Mori T., Kanbe K., Tomoda A., Takahashi A., et al. United States Patent: Method for producing scyllo-inositol. Hokko Chemicals 2004, Patent number US7745671. http://www.freepatentsonline.com/7745671.html.
-
(2004)
United States Patent: Method for producing scyllo-inositol. Hokko Chemicals
-
-
Yamaguchi, M.1
Kita, Y.2
Mori, T.3
Kanbe, K.4
Tomoda, A.5
Takahashi, A.6
-
116
-
-
80052592484
-
A cell factory of Bacillus subtilis engineered for the simple bioconversion of myo-inositol to scyllo-inositol, a potential therapeutic agent for Alzheimer's disease
-
Yamaoka M., Osawa S., Morinaga T., Takenaka S., Yoshida K. A cell factory of Bacillus subtilis engineered for the simple bioconversion of myo-inositol to scyllo-inositol, a potential therapeutic agent for Alzheimer's disease. Microbial Cell Factories 2011, 10:69.
-
(2011)
Microbial Cell Factories
, vol.10
, pp. 69
-
-
Yamaoka, M.1
Osawa, S.2
Morinaga, T.3
Takenaka, S.4
Yoshida, K.5
-
117
-
-
78649859765
-
Metabolome-wide association study identifies multiple biomarkers that discriminate north and south Chinese populations at differing risks of cardiovascular disease: INTERMAP study
-
Yap I.K., Brown I.J., Chan Q., Wijeyesekera A., Garcia-Perez I., Bictash M., et al. Metabolome-wide association study identifies multiple biomarkers that discriminate north and south Chinese populations at differing risks of cardiovascular disease: INTERMAP study. Journal of Proteome Research 2010, 9(12):6647-6654.
-
(2010)
Journal of Proteome Research
, vol.9
, Issue.12
, pp. 6647-6654
-
-
Yap, I.K.1
Brown, I.J.2
Chan, Q.3
Wijeyesekera, A.4
Garcia-Perez, I.5
Bictash, M.6
-
118
-
-
33144490687
-
Genetic modification of Bacillus subtilis for production of D-chiro-inositol, an investigational drug candidate for treatment of type 2 diabetes and polycystic ovary syndrome
-
Yoshida K., Yamaguchi M., Morinaga T., Ikeuchi M., Kinehara M., Ashida H. Genetic modification of Bacillus subtilis for production of D-chiro-inositol, an investigational drug candidate for treatment of type 2 diabetes and polycystic ovary syndrome. Applied and Environmental Microbiology 2006, 72:1310-1315.
-
(2006)
Applied and Environmental Microbiology
, vol.72
, pp. 1310-1315
-
-
Yoshida, K.1
Yamaguchi, M.2
Morinaga, T.3
Ikeuchi, M.4
Kinehara, M.5
Ashida, H.6
-
119
-
-
44849098421
-
Myo-Inositol catabolism in Bacillus subtilis
-
Yoshida K., Yamaguchi M., Morinaga T., Kinehara M., Ikeuchi M., Ashida H., et al. myo-Inositol catabolism in Bacillus subtilis. Journal Biological Chemistry 2008, 283:10415-10424.
-
(2008)
Journal Biological Chemistry
, vol.283
, pp. 10415-10424
-
-
Yoshida, K.1
Yamaguchi, M.2
Morinaga, T.3
Kinehara, M.4
Ikeuchi, M.5
Ashida, H.6
-
120
-
-
34247842999
-
Functional properties and genomics of glucose transporters
-
Zhao F., Keating A.F. Functional properties and genomics of glucose transporters. Current Genomics 2007, 8:113-128.
-
(2007)
Current Genomics
, vol.8
, pp. 113-128
-
-
Zhao, F.1
Keating, A.F.2
-
121
-
-
80052838813
-
High throughput monitoring of amyloid-β42 assembly into soluble oligomers achieved by sensitve confomation state-dependent immunoassays
-
Zhao W., Toolan D., Hepler R.W., Wolfe A.L., Yu Y., Price E., et al. High throughput monitoring of amyloid-β42 assembly into soluble oligomers achieved by sensitve confomation state-dependent immunoassays. Journal of Alzheimer's Disease 2011, 25:655-669.
-
(2011)
Journal of Alzheimer's Disease
, vol.25
, pp. 655-669
-
-
Zhao, W.1
Toolan, D.2
Hepler, R.W.3
Wolfe, A.L.4
Yu, Y.5
Price, E.6
|