메뉴 건너뛰기




Volumn 33, Issue 6, 2012, Pages 306-314

Lymphoid tissue structure and HIV-1 infection: Life or death for T cells

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CXCL13 CHEMOKINE; INTERLEUKIN 7; KERATINOCYTE GROWTH FACTOR; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; SECONDARY LYMPHOID TISSUE CHEMOKINE; STROMAL CELL DERIVED FACTOR 1; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84861702017     PISSN: 14714906     EISSN: 14714981     Source Type: Journal    
DOI: 10.1016/j.it.2012.04.002     Document Type: Review
Times cited : (82)

References (105)
  • 1
    • 58749093399 scopus 로고    scopus 로고
    • Incomplete reconstitution of T cell subsets on combination antiretroviral therapy in the AIDS Clinical Trials Group protocol 384
    • Robbins G.K., et al. Incomplete reconstitution of T cell subsets on combination antiretroviral therapy in the AIDS Clinical Trials Group protocol 384. Clin. Infect. Dis. 2009, 48:350-361.
    • (2009) Clin. Infect. Dis. , vol.48 , pp. 350-361
    • Robbins, G.K.1
  • 2
    • 0036629967 scopus 로고    scopus 로고
    • Immune restoration after treatment of HIV-1 infection with highly active antiretroviral therapy (HAART)
    • Valdez H. Immune restoration after treatment of HIV-1 infection with highly active antiretroviral therapy (HAART). AIDS Rev. 2002, 4:157-164.
    • (2002) AIDS Rev. , vol.4 , pp. 157-164
    • Valdez, H.1
  • 3
    • 0037183954 scopus 로고    scopus 로고
    • Limited immune restoration after 3 years' suppression of HIV-1 replication in patients with moderately advanced disease
    • Valdez H., et al. Limited immune restoration after 3 years' suppression of HIV-1 replication in patients with moderately advanced disease. AIDS 2002, 16:1859-1866.
    • (2002) AIDS , vol.16 , pp. 1859-1866
    • Valdez, H.1
  • 4
    • 0041631056 scopus 로고    scopus 로고
    • Factors associated with a reduced CD4 lymphocyte count response to HAART despite full viral suppression in the EuroSIDA study
    • Florence E., et al. Factors associated with a reduced CD4 lymphocyte count response to HAART despite full viral suppression in the EuroSIDA study. HIV Med. 2003, 4:255-262.
    • (2003) HIV Med. , vol.4 , pp. 255-262
    • Florence, E.1
  • 5
    • 33846439783 scopus 로고    scopus 로고
    • CD4+ cell count 6 years after commencement of highly active antiretroviral therapy in persons with sustained virologic suppression
    • Moore R.D., Keruly J.C. CD4+ cell count 6 years after commencement of highly active antiretroviral therapy in persons with sustained virologic suppression. Clin. Infect. Dis. 2007, 44:441-446.
    • (2007) Clin. Infect. Dis. , vol.44 , pp. 441-446
    • Moore, R.D.1    Keruly, J.C.2
  • 6
    • 62449222132 scopus 로고    scopus 로고
    • Incomplete peripheral CD4+ cell count restoration in HIV-infected patients receiving long-term antiretroviral treatment
    • Kelley C.F., et al. Incomplete peripheral CD4+ cell count restoration in HIV-infected patients receiving long-term antiretroviral treatment. Clin. Infect. Dis. 2009, 48:787-794.
    • (2009) Clin. Infect. Dis. , vol.48 , pp. 787-794
    • Kelley, C.F.1
  • 7
    • 80054962584 scopus 로고    scopus 로고
    • Disease-modifying therapeutic concepts for HIV in the era of highly active antiretroviral therapy
    • Butler S.L., et al. Disease-modifying therapeutic concepts for HIV in the era of highly active antiretroviral therapy. J. Acquir. Immune Defic. Syndr. 2011, 58:297-303.
    • (2011) J. Acquir. Immune Defic. Syndr. , vol.58 , pp. 297-303
    • Butler, S.L.1
  • 8
    • 64349118898 scopus 로고    scopus 로고
    • Timing of initiation of antiretroviral therapy in AIDS-free HIV-1-infected patients: a collaborative analysis of 18 HIV cohort studies
    • Sterne J.A., et al. Timing of initiation of antiretroviral therapy in AIDS-free HIV-1-infected patients: a collaborative analysis of 18 HIV cohort studies. Lancet 2009, 373:1352-1363.
    • (2009) Lancet , vol.373 , pp. 1352-1363
    • Sterne, J.A.1
  • 9
    • 84856414134 scopus 로고    scopus 로고
    • Risk factors associated with older age in treatment-naïve HIV-positive patients
    • Reuter S., et al. Risk factors associated with older age in treatment-naïve HIV-positive patients. Intervirology 2012, 55:147-153.
    • (2012) Intervirology , vol.55 , pp. 147-153
    • Reuter, S.1
  • 10
    • 0037108969 scopus 로고    scopus 로고
    • Persistent abnormalities in lymphoid tissues of human immunodeficiency virus-infected patients successfully treated with highly active antiretroviral therapy
    • Schacker T.W., et al. Persistent abnormalities in lymphoid tissues of human immunodeficiency virus-infected patients successfully treated with highly active antiretroviral therapy. J. Infect. Dis. 2002, 186:1092-1097.
    • (2002) J. Infect. Dis. , vol.186 , pp. 1092-1097
    • Schacker, T.W.1
  • 11
    • 48749093073 scopus 로고    scopus 로고
    • Collagen deposition limits immune reconstitution in the gut
    • Estes J., et al. Collagen deposition limits immune reconstitution in the gut. J. Infect. Dis. 2008, 198:456-464.
    • (2008) J. Infect. Dis. , vol.198 , pp. 456-464
    • Estes, J.1
  • 12
    • 50649117100 scopus 로고    scopus 로고
    • The role of collagen deposition in depleting CD4+ T cells and limiting reconstitution in HIV-1 and SIV infections through damage to the secondary lymphoid organ niche
    • Estes J.D., et al. The role of collagen deposition in depleting CD4+ T cells and limiting reconstitution in HIV-1 and SIV infections through damage to the secondary lymphoid organ niche. Semin. Immunol. 2008, 20:181-186.
    • (2008) Semin. Immunol. , vol.20 , pp. 181-186
    • Estes, J.D.1
  • 13
    • 0142092389 scopus 로고    scopus 로고
    • Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy
    • Guadalupe M., et al. Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J. Virol. 2003, 77:11708-11717.
    • (2003) J. Virol. , vol.77 , pp. 11708-11717
    • Guadalupe, M.1
  • 14
    • 2542480178 scopus 로고    scopus 로고
    • Hepatitis A and B vaccination practices for ambulatory patients infected with HIV
    • Tedaldi E.M., et al. Hepatitis A and B vaccination practices for ambulatory patients infected with HIV. Clin. Infect. Dis. 2004, 38:1478-1484.
    • (2004) Clin. Infect. Dis. , vol.38 , pp. 1478-1484
    • Tedaldi, E.M.1
  • 15
    • 0042160250 scopus 로고    scopus 로고
    • Response of human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy to vaccination with 23-valent pneumococcal polysaccharide vaccine
    • Rodriguez-Barradas M.C., et al. Response of human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy to vaccination with 23-valent pneumococcal polysaccharide vaccine. Clin. Infect. Dis. 2003, 37:438-447.
    • (2003) Clin. Infect. Dis. , vol.37 , pp. 438-447
    • Rodriguez-Barradas, M.C.1
  • 16
    • 0031768656 scopus 로고    scopus 로고
    • Frequency of symptomatic and asymptomatic herpes simplex virus type 2 reactivations among human immunodeficiency virus-infected men
    • Schacker T., et al. Frequency of symptomatic and asymptomatic herpes simplex virus type 2 reactivations among human immunodeficiency virus-infected men. J. Infect. Dis. 1998, 178:1616-1622.
    • (1998) J. Infect. Dis. , vol.178 , pp. 1616-1622
    • Schacker, T.1
  • 17
    • 3943108785 scopus 로고    scopus 로고
    • Frequent reactivation of herpes simplex virus among HIV-1-infected patients treated with highly active antiretroviral therapy
    • Posavad C.M., et al. Frequent reactivation of herpes simplex virus among HIV-1-infected patients treated with highly active antiretroviral therapy. J. Infect. Dis. 2004, 190:693-696.
    • (2004) J. Infect. Dis. , vol.190 , pp. 693-696
    • Posavad, C.M.1
  • 18
    • 0942290569 scopus 로고    scopus 로고
    • High prevalence of anal squamous intraepithelial lesions in HIV-positive men despite the use of highly active antiretroviral therapy
    • Piketty C., et al. High prevalence of anal squamous intraepithelial lesions in HIV-positive men despite the use of highly active antiretroviral therapy. Sex Transm. Dis. 2004, 31:96-99.
    • (2004) Sex Transm. Dis. , vol.31 , pp. 96-99
    • Piketty, C.1
  • 19
    • 43949097900 scopus 로고    scopus 로고
    • Cancer risk in people infected with human immunodeficiency virus in the United States
    • Engels E.A., et al. Cancer risk in people infected with human immunodeficiency virus in the United States. Int. J. Cancer 2008, 123:187-194.
    • (2008) Int. J. Cancer , vol.123 , pp. 187-194
    • Engels, E.A.1
  • 20
    • 42449086328 scopus 로고    scopus 로고
    • CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection
    • Baker J.V., et al. CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection. AIDS 2008, 22:841-848.
    • (2008) AIDS , vol.22 , pp. 841-848
    • Baker, J.V.1
  • 21
    • 57349124803 scopus 로고    scopus 로고
    • The role of HIV in serious diseases other than AIDS
    • Phillips A.N., et al. The role of HIV in serious diseases other than AIDS. AIDS 2008, 22:2409-2418.
    • (2008) AIDS , vol.22 , pp. 2409-2418
    • Phillips, A.N.1
  • 22
    • 85062055676 scopus 로고    scopus 로고
    • Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study
    • Weber R., et al. Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study. Arch. Intern. Med. 2006, 166:1632-1641.
    • (2006) Arch. Intern. Med. , vol.166 , pp. 1632-1641
    • Weber, R.1
  • 23
    • 52649165176 scopus 로고    scopus 로고
    • Bacterial pneumonia in HIV-infected patients: use of the pneumonia severity index and impact of current management on incidence, aetiology and outcome
    • Curran A., et al. Bacterial pneumonia in HIV-infected patients: use of the pneumonia severity index and impact of current management on incidence, aetiology and outcome. HIV Med. 2008, 9:609-615.
    • (2008) HIV Med. , vol.9 , pp. 609-615
    • Curran, A.1
  • 24
    • 33646689587 scopus 로고    scopus 로고
    • Lymphatic tissue fibrosis is associated with reduced numbers of naïve CD4+ T cells in human immunodeficiency virus type 1 infection
    • Schacker T.W., et al. Lymphatic tissue fibrosis is associated with reduced numbers of naïve CD4+ T cells in human immunodeficiency virus type 1 infection. Clin. Vaccine Immunol. 2006, 13:556-560.
    • (2006) Clin. Vaccine Immunol. , vol.13 , pp. 556-560
    • Schacker, T.W.1
  • 25
    • 0036801658 scopus 로고    scopus 로고
    • Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis
    • Schacker T.W., et al. Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis. J. Clin. Invest. 2002, 110:1133-1139.
    • (2002) J. Clin. Invest. , vol.110 , pp. 1133-1139
    • Schacker, T.W.1
  • 26
    • 0032971372 scopus 로고    scopus 로고
    • Population biology of HIV-1 infection: viral and CD4+ T cell demographics and dynamics in lymphatic tissues
    • Haase A.T. Population biology of HIV-1 infection: viral and CD4+ T cell demographics and dynamics in lymphatic tissues. Annu. Rev. Immunol. 1999, 17:625-656.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 625-656
    • Haase, A.T.1
  • 27
    • 77955421014 scopus 로고    scopus 로고
    • Factors associated with collagen deposition in lymphoid tissue in long-term treated HIV-infected patients
    • Diaz A., et al. Factors associated with collagen deposition in lymphoid tissue in long-term treated HIV-infected patients. AIDS 2010, 24:2029-2039.
    • (2010) AIDS , vol.24 , pp. 2029-2039
    • Diaz, A.1
  • 28
    • 79952340014 scopus 로고    scopus 로고
    • Lymphoid tissue collagen deposition in HIV-infected patients correlates with the imbalance between matrix metalloproteinases and their inhibitors
    • Diaz A., et al. Lymphoid tissue collagen deposition in HIV-infected patients correlates with the imbalance between matrix metalloproteinases and their inhibitors. J. Infect. Dis. 2011, 203:810-813.
    • (2011) J. Infect. Dis. , vol.203 , pp. 810-813
    • Diaz, A.1
  • 29
    • 33144476838 scopus 로고    scopus 로고
    • Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection
    • Estes J.D., et al. Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection. J. Infect. Dis. 2006, 193:703-712.
    • (2006) J. Infect. Dis. , vol.193 , pp. 703-712
    • Estes, J.D.1
  • 30
    • 33846785628 scopus 로고    scopus 로고
    • Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection
    • Estes J.D., et al. Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection. J. Infect. Dis. 2007, 195:551-561.
    • (2007) J. Infect. Dis. , vol.195 , pp. 551-561
    • Estes, J.D.1
  • 31
    • 67650699827 scopus 로고    scopus 로고
    • Evaluation of the pathogenesis of decreasing CD4(+) T cell counts in human immunodeficiency virus type 1-infected patients receiving successfully suppressive antiretroviral therapy
    • Nies-Kraske E., et al. Evaluation of the pathogenesis of decreasing CD4(+) T cell counts in human immunodeficiency virus type 1-infected patients receiving successfully suppressive antiretroviral therapy. J. Infect. Dis. 2009, 199:1648-1656.
    • (2009) J. Infect. Dis. , vol.199 , pp. 1648-1656
    • Nies-Kraske, E.1
  • 32
    • 27944487152 scopus 로고    scopus 로고
    • Amount of lymphatic tissue fibrosis in HIV infection predicts magnitude of HAART-associated change in peripheral CD4 cell count
    • Schacker T.W., et al. Amount of lymphatic tissue fibrosis in HIV infection predicts magnitude of HAART-associated change in peripheral CD4 cell count. AIDS 2005, 19:2169-2171.
    • (2005) AIDS , vol.19 , pp. 2169-2171
    • Schacker, T.W.1
  • 33
    • 79952216365 scopus 로고    scopus 로고
    • Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections
    • Zeng M., et al. Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections. J. Clin. Invest. 2011, 121:998-1008.
    • (2011) J. Clin. Invest. , vol.121 , pp. 998-1008
    • Zeng, M.1
  • 34
    • 84857479601 scopus 로고    scopus 로고
    • Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy
    • Zeng M., et al. Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy. PLoS Pathog. 2012, 8:e1002437.
    • (2012) PLoS Pathog. , vol.8
    • Zeng, M.1
  • 35
    • 72949100401 scopus 로고    scopus 로고
    • Naïve T cell homeostasis: from awareness of space to a sense of place
    • Takada K., Jameson S.C. Naïve T cell homeostasis: from awareness of space to a sense of place. Nat. Rev. Immunol. 2009, 9:823-832.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 823-832
    • Takada, K.1    Jameson, S.C.2
  • 36
    • 43449105029 scopus 로고    scopus 로고
    • T cell homeostasis
    • Sprent J., et al. T cell homeostasis. Immunol. Cell Biol. 2008, 86:312-319.
    • (2008) Immunol. Cell Biol. , vol.86 , pp. 312-319
    • Sprent, J.1
  • 37
    • 0035902513 scopus 로고    scopus 로고
    • IL-7 is critical for homeostatic proliferation and survival of naïve T cells
    • Tan J.T., et al. IL-7 is critical for homeostatic proliferation and survival of naïve T cells. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:8732-8737.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 8732-8737
    • Tan, J.T.1
  • 38
    • 57449097558 scopus 로고    scopus 로고
    • Homeostasis of naïve and memory T cells
    • Surh C.D., Sprent J. Homeostasis of naïve and memory T cells. Immunity 2008, 29:848-862.
    • (2008) Immunity , vol.29 , pp. 848-862
    • Surh, C.D.1    Sprent, J.2
  • 39
    • 77953749960 scopus 로고    scopus 로고
    • Generation of effector CD8+ T cells and their conversion to memory T cells
    • Cui W., Kaech S.M. Generation of effector CD8+ T cells and their conversion to memory T cells. Immunol. Rev. 2010, 236:151-166.
    • (2010) Immunol. Rev. , vol.236 , pp. 151-166
    • Cui, W.1    Kaech, S.M.2
  • 41
    • 0034124915 scopus 로고    scopus 로고
    • The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infection
    • Haynes B.F., et al. The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infection. Annu. Rev. Immunol. 2000, 18:529-560.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 529-560
    • Haynes, B.F.1
  • 42
    • 84857416171 scopus 로고    scopus 로고
    • Maintenance of peripheral naïve T cells is sustained by thymus output in mice but not humans
    • den Braber I., et al. Maintenance of peripheral naïve T cells is sustained by thymus output in mice but not humans. Immunity 2012, 36:288-297.
    • (2012) Immunity , vol.36 , pp. 288-297
    • den Braber, I.1
  • 43
    • 13144279356 scopus 로고    scopus 로고
    • Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection
    • Zhang Z.Q., et al. Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:1154-1159.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 1154-1159
    • Zhang, Z.Q.1
  • 44
    • 0033557266 scopus 로고    scopus 로고
    • Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection
    • Haynes B.F., et al. Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection. J. Clin. Invest. 1999, 103:921.
    • (1999) J. Clin. Invest. , vol.103 , pp. 921
    • Haynes, B.F.1
  • 45
    • 0031759778 scopus 로고    scopus 로고
    • The human thymus. A chimeric organ comprised of central and peripheral lymphoid components
    • Haynes B.F., Hale L.P. The human thymus. A chimeric organ comprised of central and peripheral lymphoid components. Immunol. Res. 1998, 18:175-192.
    • (1998) Immunol. Res. , vol.18 , pp. 175-192
    • Haynes, B.F.1    Hale, L.P.2
  • 46
    • 0032101595 scopus 로고    scopus 로고
    • Early regeneration of thymic progenitors in rhesus macaques infected with simian immunodeficiency virus
    • Wykrzykowska J.J., et al. Early regeneration of thymic progenitors in rhesus macaques infected with simian immunodeficiency virus. J. Exp. Med. 1998, 187:1767-1778.
    • (1998) J. Exp. Med. , vol.187 , pp. 1767-1778
    • Wykrzykowska, J.J.1
  • 47
    • 17444372347 scopus 로고    scopus 로고
    • Changes in thymic function with age and during the treatment of HIV infection
    • Douek D.C., et al. Changes in thymic function with age and during the treatment of HIV infection. Nature 1998, 396:690-695.
    • (1998) Nature , vol.396 , pp. 690-695
    • Douek, D.C.1
  • 48
    • 1542312651 scopus 로고    scopus 로고
    • T-cell receptor excision circles (TREC) in SHIV 89.6p and SIVmac251 models of HIV-1 infection
    • Richardson M.W., et al. T-cell receptor excision circles (TREC) in SHIV 89.6p and SIVmac251 models of HIV-1 infection. DNA Cell Biol. 2004, 23:1-13.
    • (2004) DNA Cell Biol. , vol.23 , pp. 1-13
    • Richardson, M.W.1
  • 49
    • 0034685170 scopus 로고    scopus 로고
    • Effect of recent thymic emigrants on progression of HIV-1 disease
    • Hatzakis A., et al. Effect of recent thymic emigrants on progression of HIV-1 disease. Lancet 2000, 355:599-604.
    • (2000) Lancet , vol.355 , pp. 599-604
    • Hatzakis, A.1
  • 50
    • 0031882434 scopus 로고    scopus 로고
    • Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation
    • Pakker N.G., et al. Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation. Nat. Med. 1998, 4:208-214.
    • (1998) Nat. Med. , vol.4 , pp. 208-214
    • Pakker, N.G.1
  • 51
    • 0032741277 scopus 로고    scopus 로고
    • Initial increase in blood CD4(+) lymphocytes after HIV antiretroviral therapy reflects redistribution from lymphoid tissues
    • Bucy R.P., et al. Initial increase in blood CD4(+) lymphocytes after HIV antiretroviral therapy reflects redistribution from lymphoid tissues. J. Clin. Invest. 1999, 103:1391-1398.
    • (1999) J. Clin. Invest. , vol.103 , pp. 1391-1398
    • Bucy, R.P.1
  • 52
    • 12344285945 scopus 로고    scopus 로고
    • Impact of thymectomy on the peripheral T cell pool in rhesus macaques before and after infection with simian immunodeficiency virus
    • Arron S.T., et al. Impact of thymectomy on the peripheral T cell pool in rhesus macaques before and after infection with simian immunodeficiency virus. Eur. J. Immunol. 2005, 35:46-55.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 46-55
    • Arron, S.T.1
  • 53
    • 0032858367 scopus 로고    scopus 로고
    • Measuring recent thymic emigrants in blood of normal and HIV-1-infected individuals before and after effective therapy
    • Zhang L., et al. Measuring recent thymic emigrants in blood of normal and HIV-1-infected individuals before and after effective therapy. J. Exp. Med. 1999, 190:725-732.
    • (1999) J. Exp. Med. , vol.190 , pp. 725-732
    • Zhang, L.1
  • 54
    • 0031849216 scopus 로고    scopus 로고
    • Peripheral expansion of pre-existing mature T cells is an important means of CD4+ T-cell regeneration HIV-infected adults
    • Walker R.E., et al. Peripheral expansion of pre-existing mature T cells is an important means of CD4+ T-cell regeneration HIV-infected adults. Nat. Med. 1998, 4:852-856.
    • (1998) Nat. Med. , vol.4 , pp. 852-856
    • Walker, R.E.1
  • 55
    • 63449124466 scopus 로고    scopus 로고
    • Emerging concepts in the immunopathogenesis of AIDS
    • Douek D.C., et al. Emerging concepts in the immunopathogenesis of AIDS. Annu. Rev. Med. 2009, 60:471-484.
    • (2009) Annu. Rev. Med. , vol.60 , pp. 471-484
    • Douek, D.C.1
  • 56
    • 3843056825 scopus 로고    scopus 로고
    • Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load
    • Deeks S.G., et al. Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load. Blood 2004, 104:942-947.
    • (2004) Blood , vol.104 , pp. 942-947
    • Deeks, S.G.1
  • 57
    • 0038701685 scopus 로고    scopus 로고
    • T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy
    • Hunt P.W., et al. T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy. J. Infect. Dis. 2003, 187:1534-1543.
    • (2003) J. Infect. Dis. , vol.187 , pp. 1534-1543
    • Hunt, P.W.1
  • 58
    • 36048968755 scopus 로고    scopus 로고
    • Understanding the benign nature of SIV infection in natural hosts
    • Silvestri G., et al. Understanding the benign nature of SIV infection in natural hosts. J. Clin. Invest. 2007, 117:3148-3154.
    • (2007) J. Clin. Invest. , vol.117 , pp. 3148-3154
    • Silvestri, G.1
  • 59
    • 0031462792 scopus 로고    scopus 로고
    • T cell turnover in HIV-1 disease
    • Hellerstein M.K., McCune J.M. T cell turnover in HIV-1 disease. Immunity 1997, 7:583-589.
    • (1997) Immunity , vol.7 , pp. 583-589
    • Hellerstein, M.K.1    McCune, J.M.2
  • 60
    • 0041888480 scopus 로고    scopus 로고
    • T cell dynamics in HIV-1 infection
    • Douek D.C., et al. T cell dynamics in HIV-1 infection. Annu. Rev. Immunol. 2003, 21:265-304.
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 265-304
    • Douek, D.C.1
  • 61
    • 0032568603 scopus 로고    scopus 로고
    • Multiple modes of cellular activation and virus transmission in HIV infection: a role for chronically and latently infected cells in sustaining viral replication
    • Grossman Z., et al. Multiple modes of cellular activation and virus transmission in HIV infection: a role for chronically and latently infected cells in sustaining viral replication. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:6314-6319.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 6314-6319
    • Grossman, Z.1
  • 62
    • 0242320524 scopus 로고    scopus 로고
    • Disrupting T-cell homeostasis: how HIV-1 infection causes disease
    • Douek D.C. Disrupting T-cell homeostasis: how HIV-1 infection causes disease. AIDS Rev. 2003, 5:172-177.
    • (2003) AIDS Rev. , vol.5 , pp. 172-177
    • Douek, D.C.1
  • 63
    • 0030944142 scopus 로고    scopus 로고
    • Cords, channels, corridors and conduits: critical architectural elements facilitating cell interactions in the lymph node cortex
    • Gretz J.E., et al. Cords, channels, corridors and conduits: critical architectural elements facilitating cell interactions in the lymph node cortex. Immunol. Rev. 1997, 156:11-24.
    • (1997) Immunol. Rev. , vol.156 , pp. 11-24
    • Gretz, J.E.1
  • 64
    • 0029902442 scopus 로고    scopus 로고
    • Sophisticated strategies for information encounter in the lymph node: the reticular network as a conduit of soluble information and a highway for cell traffic
    • Gretz J.E., et al. Sophisticated strategies for information encounter in the lymph node: the reticular network as a conduit of soluble information and a highway for cell traffic. J. Immunol. 1996, 157:495-499.
    • (1996) J. Immunol. , vol.157 , pp. 495-499
    • Gretz, J.E.1
  • 65
    • 0034776180 scopus 로고    scopus 로고
    • Spatial and molecular organization of lymph node T cell cortex: a labyrinthine cavity bounded by an epithelium-like monolayer of fibroblastic reticular cells anchored to basement membrane-like extracellular matrix
    • Kaldjian E.P., et al. Spatial and molecular organization of lymph node T cell cortex: a labyrinthine cavity bounded by an epithelium-like monolayer of fibroblastic reticular cells anchored to basement membrane-like extracellular matrix. Int. Immunol. 2001, 13:1243-1253.
    • (2001) Int. Immunol. , vol.13 , pp. 1243-1253
    • Kaldjian, E.P.1
  • 66
    • 35548975191 scopus 로고    scopus 로고
    • Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naïve T cells
    • Link A., et al. Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naïve T cells. Nat. Immunol. 2007, 8:1255-1265.
    • (2007) Nat. Immunol. , vol.8 , pp. 1255-1265
    • Link, A.1
  • 67
    • 0023801437 scopus 로고
    • Direct contact between reticular fibers and migratory cells in the paracortex of mouse lymph nodes: a morphological and quantitative study
    • Hayakawa M., et al. Direct contact between reticular fibers and migratory cells in the paracortex of mouse lymph nodes: a morphological and quantitative study. Arch. Histol. Cytol. 1988, 51:233-240.
    • (1988) Arch. Histol. Cytol. , vol.51 , pp. 233-240
    • Hayakawa, M.1
  • 68
    • 0035892899 scopus 로고    scopus 로고
    • IL-7 enhances the survival and maintains the size of naïve T cells
    • Rathmell J.C., et al. IL-7 enhances the survival and maintains the size of naïve T cells. J. Immunol. 2001, 167:6869-6876.
    • (2001) J. Immunol. , vol.167 , pp. 6869-6876
    • Rathmell, J.C.1
  • 69
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo
    • Schluns K.S., et al. Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo. Nat. Immunol. 2000, 1:426-432.
    • (2000) Nat. Immunol. , vol.1 , pp. 426-432
    • Schluns, K.S.1
  • 70
    • 12444297666 scopus 로고    scopus 로고
    • The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node
    • Sixt M., et al. The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node. Immunity 2005, 22:19-29.
    • (2005) Immunity , vol.22 , pp. 19-29
    • Sixt, M.1
  • 71
    • 4344651077 scopus 로고    scopus 로고
    • A novel reticular stromal structure in lymph node cortex: an immuno-platform for interactions among dendritic cells, T cells and B cells
    • Katakai T., et al. A novel reticular stromal structure in lymph node cortex: an immuno-platform for interactions among dendritic cells, T cells and B cells. Int. Immunol. 2004, 16:1133-1142.
    • (2004) Int. Immunol. , vol.16 , pp. 1133-1142
    • Katakai, T.1
  • 72
    • 0347717903 scopus 로고    scopus 로고
    • T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
    • Mempel T.R., et al. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 2004, 427:154-159.
    • (2004) Nature , vol.427 , pp. 154-159
    • Mempel, T.R.1
  • 73
    • 0034693949 scopus 로고    scopus 로고
    • Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex
    • Gretz J.E., et al. Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex. J. Exp. Med. 2000, 192:1425-1440.
    • (2000) J. Exp. Med. , vol.192 , pp. 1425-1440
    • Gretz, J.E.1
  • 74
    • 33845455093 scopus 로고    scopus 로고
    • Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes
    • Bajenoff M., et al. Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity 2006, 25:989-1001.
    • (2006) Immunity , vol.25 , pp. 989-1001
    • Bajenoff, M.1
  • 75
    • 81855203183 scopus 로고    scopus 로고
    • Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules
    • Moussion C., Girard J.P. Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules. Nature 2011, 479:542-546.
    • (2011) Nature , vol.479 , pp. 542-546
    • Moussion, C.1    Girard, J.P.2
  • 76
    • 84255177550 scopus 로고    scopus 로고
    • Lymph node T cell homeostasis relies on steady state homing of dendritic cells
    • Wendland M., et al. Lymph node T cell homeostasis relies on steady state homing of dendritic cells. Immunity 2011, 35:945-957.
    • (2011) Immunity , vol.35 , pp. 945-957
    • Wendland, M.1
  • 77
    • 2442606191 scopus 로고    scopus 로고
    • Lymphocyte trafficking across high endothelial venules: dogmas and enigmas
    • Miyasaka M., Tanaka T. Lymphocyte trafficking across high endothelial venules: dogmas and enigmas. Nat. Rev. Immunol. 2004, 4:360-370.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 360-370
    • Miyasaka, M.1    Tanaka, T.2
  • 78
    • 0242551584 scopus 로고    scopus 로고
    • Homing and cellular traffic in lymph nodes
    • von Andrian U.H., Mempel T.R. Homing and cellular traffic in lymph nodes. Nat. Rev. Immunol. 2003, 3:867-878.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 867-878
    • von Andrian, U.H.1    Mempel, T.R.2
  • 79
    • 0033214348 scopus 로고    scopus 로고
    • CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
    • Forster R., et al. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 1999, 99:23-33.
    • (1999) Cell , vol.99 , pp. 23-33
    • Forster, R.1
  • 80
    • 0033081760 scopus 로고    scopus 로고
    • Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization
    • Gunn M.D., et al. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J. Exp. Med. 1999, 189:451-460.
    • (1999) J. Exp. Med. , vol.189 , pp. 451-460
    • Gunn, M.D.1
  • 81
    • 70249143637 scopus 로고    scopus 로고
    • Homeostatic proliferation and survival of naïve and memory T cells
    • Boyman O., et al. Homeostatic proliferation and survival of naïve and memory T cells. Eur. J. Immunol. 2009, 39:2088-2094.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 2088-2094
    • Boyman, O.1
  • 82
    • 0023109158 scopus 로고
    • The histologic features of hyperplastic lymphadenopathy in AIDS-related complex are nonspecific
    • O'Murchadha M.T., et al. The histologic features of hyperplastic lymphadenopathy in AIDS-related complex are nonspecific. Am. J. Surg. Pathol. 1987, 11:94-99.
    • (1987) Am. J. Surg. Pathol. , vol.11 , pp. 94-99
    • O'Murchadha, M.T.1
  • 83
    • 85012474693 scopus 로고
    • New concepts in the immunopathogenesis of human immunodeficiency virus infection
    • Pantaleo G., et al. New concepts in the immunopathogenesis of human immunodeficiency virus infection. N. Engl. J. Med. 1993, 328:327-335.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 327-335
    • Pantaleo, G.1
  • 84
    • 4644284542 scopus 로고    scopus 로고
    • Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes
    • Katakai T., et al. Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes. J. Exp. Med. 2004, 200:783-795.
    • (2004) J. Exp. Med. , vol.200 , pp. 783-795
    • Katakai, T.1
  • 85
    • 0033068145 scopus 로고    scopus 로고
    • Lymphotoxin alphabeta is expressed on recently activated naïve and Th1-like CD4 cells but is down-regulated by IL-4 during Th2 differentiation
    • Gramaglia I., et al. Lymphotoxin alphabeta is expressed on recently activated naïve and Th1-like CD4 cells but is down-regulated by IL-4 during Th2 differentiation. J. Immunol. 1999, 162:1333-1338.
    • (1999) J. Immunol. , vol.162 , pp. 1333-1338
    • Gramaglia, I.1
  • 86
    • 0033120079 scopus 로고    scopus 로고
    • Naïve human CD4+ T cells are a major source of lymphotoxin alpha
    • Ohshima Y., et al. Naïve human CD4+ T cells are a major source of lymphotoxin alpha. J. Immunol. 1999, 162:3790-3794.
    • (1999) J. Immunol. , vol.162 , pp. 3790-3794
    • Ohshima, Y.1
  • 87
    • 77954630522 scopus 로고    scopus 로고
    • Early versus standard antiretroviral therapy for HIV-infected adults in Haiti
    • Severe P., et al. Early versus standard antiretroviral therapy for HIV-infected adults in Haiti. N. Engl. J. Med. 2010, 363:257-265.
    • (2010) N. Engl. J. Med. , vol.363 , pp. 257-265
    • Severe, P.1
  • 88
    • 0038142359 scopus 로고    scopus 로고
    • Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1
    • Donaghy H., et al. Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1. Blood 2003, 101:4505-4511.
    • (2003) Blood , vol.101 , pp. 4505-4511
    • Donaghy, H.1
  • 89
    • 0035894221 scopus 로고    scopus 로고
    • Interleukin-7 receptor expression on CD8(+) T cells is reduced in HIV infection and partially restored with effective antiretroviral therapy
    • MacPherson P.A., et al. Interleukin-7 receptor expression on CD8(+) T cells is reduced in HIV infection and partially restored with effective antiretroviral therapy. J. Acquir. Immune Defic. Syndr. 2001, 28:454-457.
    • (2001) J. Acquir. Immune Defic. Syndr. , vol.28 , pp. 454-457
    • MacPherson, P.A.1
  • 90
    • 32944455546 scopus 로고    scopus 로고
    • IL-7Ralpha expression on CD4+ T lymphocytes decreases with HIV disease progression and inversely correlates with immune activation
    • Koesters S.A., et al. IL-7Ralpha expression on CD4+ T lymphocytes decreases with HIV disease progression and inversely correlates with immune activation. Eur. J. Immunol. 2006, 36:336-344.
    • (2006) Eur. J. Immunol. , vol.36 , pp. 336-344
    • Koesters, S.A.1
  • 91
    • 34347400589 scopus 로고    scopus 로고
    • Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques
    • Seggewiss R., et al. Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques. Blood 2007, 110:441-449.
    • (2007) Blood , vol.110 , pp. 441-449
    • Seggewiss, R.1
  • 92
    • 0037097583 scopus 로고    scopus 로고
    • Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation
    • Min D., et al. Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation. Blood 2002, 99:4592-4600.
    • (2002) Blood , vol.99 , pp. 4592-4600
    • Min, D.1
  • 93
    • 70350441282 scopus 로고    scopus 로고
    • Interleukin-2 therapy in patients with HIV infection
    • Abrams D., et al. Interleukin-2 therapy in patients with HIV infection. N. Engl. J. Med. 2009, 361:1548-1559.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 1548-1559
    • Abrams, D.1
  • 94
    • 77953748800 scopus 로고    scopus 로고
    • In vivo expansion of naïve and activated CD4+CD25+FOXP3+ regulatory T cell populations in interleukin-2-treated HIV patients
    • Weiss L., et al. In vivo expansion of naïve and activated CD4+CD25+FOXP3+ regulatory T cell populations in interleukin-2-treated HIV patients. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:10632-10637.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 10632-10637
    • Weiss, L.1
  • 95
    • 0037443464 scopus 로고    scopus 로고
    • IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates
    • Fry T.J., et al. IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates. Blood 2003, 101:2294-2299.
    • (2003) Blood , vol.101 , pp. 2294-2299
    • Fry, T.J.1
  • 96
    • 65249105408 scopus 로고    scopus 로고
    • Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment
    • Levy Y., et al. Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment. J. Clin. Invest. 2009, 119:997-1007.
    • (2009) J. Clin. Invest. , vol.119 , pp. 997-1007
    • Levy, Y.1
  • 97
    • 33847771726 scopus 로고    scopus 로고
    • Interleukin 7 reduces the levels of spontaneous apoptosis in CD4+ and CD8+ T cells from HIV-1-infected individuals
    • Vassena L., et al. Interleukin 7 reduces the levels of spontaneous apoptosis in CD4+ and CD8+ T cells from HIV-1-infected individuals. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:2355-2360.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 2355-2360
    • Vassena, L.1
  • 98
    • 0030709198 scopus 로고    scopus 로고
    • Antifibrotic effect of decorin in a bleomycin hamster model of lung fibrosis
    • Giri S.N., et al. Antifibrotic effect of decorin in a bleomycin hamster model of lung fibrosis. Biochem. Pharmacol. 1997, 54:1205-1216.
    • (1997) Biochem. Pharmacol. , vol.54 , pp. 1205-1216
    • Giri, S.N.1
  • 99
    • 0033524949 scopus 로고    scopus 로고
    • The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis
    • Munger J.S., et al. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell 1999, 96:319-328.
    • (1999) Cell , vol.96 , pp. 319-328
    • Munger, J.S.1
  • 100
    • 20244383986 scopus 로고    scopus 로고
    • Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor
    • Bonniaud P., et al. Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor. Am. J. Respir. Crit. Care Med. 2005, 171:889-898.
    • (2005) Am. J. Respir. Crit. Care Med. , vol.171 , pp. 889-898
    • Bonniaud, P.1
  • 101
    • 0032719815 scopus 로고    scopus 로고
    • Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice
    • Nakao A., et al. Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice. J. Clin. Invest. 1999, 104:5-11.
    • (1999) J. Clin. Invest. , vol.104 , pp. 5-11
    • Nakao, A.1
  • 102
    • 4243844292 scopus 로고    scopus 로고
    • Roles of TGF-beta in hepatic fibrosis
    • Gressner A.M., et al. Roles of TGF-beta in hepatic fibrosis. Front. Biosci. 2002, 7:d793-d807.
    • (2002) Front. Biosci. , vol.7
    • Gressner, A.M.1
  • 103
    • 77951160564 scopus 로고    scopus 로고
    • Pirfenidone in idiopathic pulmonary fibrosis
    • Taniguchi H., et al. Pirfenidone in idiopathic pulmonary fibrosis. Eur. Respir. J. 2010, 35:821-829.
    • (2010) Eur. Respir. J. , vol.35 , pp. 821-829
    • Taniguchi, H.1
  • 104
    • 44049100259 scopus 로고    scopus 로고
    • Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone
    • Scandella E., et al. Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone. Nat. immunol. 2008, 9:667-675.
    • (2008) Nat. immunol. , vol.9 , pp. 667-675
    • Scandella, E.1
  • 105
    • 84859497086 scopus 로고    scopus 로고
    • Interleukin-22 drives endogenous thymic regeneration in mice
    • Dudakov J.A., et al. Interleukin-22 drives endogenous thymic regeneration in mice. Science 2012, 336:91-95.
    • (2012) Science , vol.336 , pp. 91-95
    • Dudakov, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.