Cytotoxic Capacity of SIV-Specific CD8+ T Cells against Primary Autologous Targets Correlates with Immune Control in SIV-Infected Rhesus Macaques

PLoS Pathogens

Volumn 9, Issue 2, 2013, Pages

  Mendoza, Daniel ^a   Migueles, Stephen A ^a   Rood, Julia E ^a   Peterson, Bennett ^a   Johnson, Sarah ^a   Doria Rose, Nicole ^a   Schneider, Douglas ^b   Rakasz, Eva ^c   Trivett, Matthew T ^b   Trubey, Charles M ^b   Coalter, Vicky ^b   Hallahan, Claire W ^a   Watkins, David ^c,d   Franchini, Genoveffa ^e   Lifson, Jeffrey D ^b   Connors, Mark ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b SAIC FREDERICK INC   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM IONOPHORE; GRANZYME B; INTERLEUKIN 2; NERVE GROWTH FACTOR RECEPTOR; PHORBOL ESTER; PROTEIN P27; TELOMERASE REVERSE TRANSCRIPTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD8+ T LYMPHOCYTE; CELL ACTIVITY; CELL KILLING; CELL STIMULATION; CONTROLLED STUDY; CYTOTOXICITY; EXOCYTOSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; RHESUS MONKEY; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; VIRUS LOAD; VIRUS REPLICATION;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; DISEASE PROGRESSION; HOST-PATHOGEN INTERACTIONS; IMMUNITY; MACACA MULATTA; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; T-LYMPHOCYTES, CYTOTOXIC; VIRUS REPLICATION;

EID: 84879077369     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003195     Document Type: Article

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