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Volumn 2011, Issue , 2011, Pages

The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion

Author keywords

[No Author keywords available]

Indexed keywords

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CYCLOSPORIN A; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTION FACTOR NFAT; CD28 ANTIGEN;

EID: 81555226044     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2011/451694     Document Type: Review
Times cited : (120)

References (79)
  • 1
    • 34848831575 scopus 로고    scopus 로고
    • The B7 family and cancer therapy: Costimulation and coinhibition
    • DOI 10.1158/1078-0432.CCR-07-1030
    • Zang X., Allison J. P., The B7 family and cancer therapy: costimulation and coinhibition Clinical Cancer Research 2007 13 18, part 1 5271 5279 (Pubitemid 47510350)
    • (2007) Clinical Cancer Research , vol.13 , Issue.18 , pp. 5271-5279
    • Zang, X.1    Allison, J.P.2
  • 2
    • 0026700235 scopus 로고
    • Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
    • Ishida Y., Agata Y., Shibahara K., Honjo T., Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death The EMBO Journal 1992 11 11 3887 3895
    • (1992) The EMBO Journal , vol.11 , Issue.11 , pp. 3887-3895
    • Ishida, Y.1    Agata, Y.2    Shibahara, K.3    Honjo, T.4
  • 4
    • 0031562690 scopus 로고    scopus 로고
    • Activation-induced expression of human programmed death-1 gene in T- lymphocytes
    • DOI 10.1006/excr.1997.3493
    • Vibhakar R., Juan G., Traganos F., Darzynkiewicz Z., Finger L. R., Activation-induced expression of human programmed death-1 gene in T- lymphocytes Experimental Cell Research 1997 232 1 25 28 (Pubitemid 27172215)
    • (1997) Experimental Cell Research , vol.232 , Issue.1 , pp. 25-28
    • Vibhakar, R.1    Juan, G.2    Traganos, F.3    Darzynkiewicz, Z.4    Finger, L.R.5
  • 8
    • 0032736029 scopus 로고    scopus 로고
    • B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
    • Dong H., Zhu G., Tamada K., Chen L., B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion Nature Medicine 1999 5 12 1365 1369
    • (1999) Nature Medicine , vol.5 , Issue.12 , pp. 1365-1369
    • Dong, H.1    Zhu, G.2    Tamada, K.3    Chen, L.4
  • 13
    • 31444451661 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-induced upregulation of B7-H1 (CD274)
    • DOI 10.1016/j.febslet.2005.12.093, PII S0014579306000044
    • Lee S. J., Jang B. C., Lee S. W., Yang Y. I., Suh S. I., Park Y. M., Oh S., Shin J. G., Yao S., Chen L., Choi I. H., Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN- -induced upregulation of B7-H1 (CD274) FEBS Letters 2006 580 3 755 762 (Pubitemid 43152293)
    • (2006) FEBS Letters , vol.580 , Issue.3 , pp. 755-762
    • Lee, S.-J.1    Jang, B.-C.2    Lee, S.-W.3    Yang, Y.-I.4    Suh, S.-I.5    Park, Y.-M.6    Oh, S.7    Shin, J.-G.8    Yao, S.9    Chen, L.10    Choi, I.-H.11
  • 16
    • 0035923535 scopus 로고    scopus 로고
    • PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine
    • DOI 10.1073/pnas.231486598
    • Okazaki T., Maeda A., Nishimura H., Kurosaki T., Honjo T., PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine Proceedings of the National Academy of Sciences of the United States of America 2001 98 24 13866 13871 (Pubitemid 33115990)
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , Issue.24 , pp. 13866-13871
    • Okazaki, T.1    Maeda, A.2    Nishimura, H.3    Kurosaki, T.4    Honjo, T.5
  • 17
    • 3142688997 scopus 로고    scopus 로고
    • SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation
    • Chemnitz J. M., Parry R. V., Nichols K. E., June C. H., Riley J. L., SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation The Journal of Immunology 2004 173 2 945 954 (Pubitemid 38924267)
    • (2004) Journal of Immunology , vol.173 , Issue.2 , pp. 945-954
    • Chemnitz, J.M.1    Parry, R.V.2    Nichols, K.E.3    June, C.H.4    Riley, J.L.5
  • 18
    • 4444317516 scopus 로고    scopus 로고
    • PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3 signalosome and downstream signaling to PKC
    • DOI 10.1016/j.febslet.2004.07.083, PII S0014579304009779
    • Sheppard K. A., Fitz L. J., Lee J. M., Benander C., George J. A., Wooters J., Qiu Y., Jussif J. M., Carter L. L., Wood C. R., Chaudhary D., PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3 signalosome and downstream signaling to PKCθ FEBS Letters 2004 574 1-3 37 41 (Pubitemid 39200891)
    • (2004) FEBS Letters , vol.574 , Issue.1-3 , pp. 37-41
    • Sheppard, K.-A.1    Fitz, L.J.2    Lee, J.M.3    Benander, C.4    George, J.A.5    Wooters, J.6    Qiu, Y.7    Jussif, J.M.8    Carter, L.L.9    Wood, C.R.10    Chaudhary, D.11
  • 20
    • 34447646310 scopus 로고    scopus 로고
    • Programmed Death-1 Ligand 1 Interacts Specifically with the B7-1 Costimulatory Molecule to Inhibit T Cell Responses
    • DOI 10.1016/j.immuni.2007.05.016, PII S1074761307003287
    • Butte M. J., Keir M. E., Phamduy T. B., Sharpe A. H., Freeman G. J., Programmed Death-1 Ligand 1 Interacts Specifically with the B7-1 Costimulatory Molecule to Inhibit T Cell Responses Immunity 2007 27 1 111 122 (Pubitemid 47089023)
    • (2007) Immunity , vol.27 , Issue.1 , pp. 111-122
    • Butte, M.J.1    Keir, M.E.2    Phamduy, T.B.3    Sharpe, A.H.4    Freeman, G.J.5
  • 21
    • 0033180181 scopus 로고    scopus 로고
    • Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
    • DOI 10.1016/S1074-7613(00)80089-8
    • Nishimura H., Nose M., Hiai H., Minato N., Honjo T., Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor Immunity 1999 11 2 141 151 (Pubitemid 29428807)
    • (1999) Immunity , vol.11 , Issue.2 , pp. 141-151
    • Nishimura, H.1    Nose, M.2    Hiai, H.3    Minato, N.4    Honjo, T.5
  • 23
    • 0037815272 scopus 로고    scopus 로고
    • PD-1 inhibits antiviral immunity at the effector phase in the liver
    • DOI 10.1084/jem.20022235
    • Iwai Y., Terawaki S., Ikegawa M., Okazaki T., Honjo T., PD-1 inhibits antiviral immunity at the effector phase in the liver The Journal of Experimental Medicine 2003 198 1 39 50 (Pubitemid 36870184)
    • (2003) Journal of Experimental Medicine , vol.198 , Issue.1 , pp. 39-50
    • Iwai, Y.1    Terawaki, S.2    Ikegawa, M.3    Okazaki, T.4    Honjo, T.5
  • 27
    • 0032482176 scopus 로고    scopus 로고
    • Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes
    • DOI 10.1084/jem.187.9.1383
    • Gallimore A., Glithero A., Godkin A., Tissot A. C., Plckthun A., Elliott T., Hengartner H., Zinkernagel R., Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes The Journal of Experimental Medicine 1998 187 9 1383 1393 (Pubitemid 28215398)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.9 , pp. 1383-1393
    • Gallimore, A.1    Glithero, A.2    Godkin, A.3    Tissot, A.C.4    Pluckthun, A.5    Elliott, T.6    Hengartner, H.7    Zinkernagel, R.8
  • 29
    • 32544459770 scopus 로고    scopus 로고
    • Restoring function in exhausted CD8 T cells during chronic viral infection
    • DOI 10.1038/nature04444, PII NATURE04444
    • Barber D. L., Wherry E. J., Masopust D., Zhu B., Allison J. P., Sharpe A. H., Freeman G. J., Ahmed R., Restoring function in exhausted CD8 T cells during chronic viral infection Nature 2006 439 7077 682 687 (Pubitemid 43237609)
    • (2006) Nature , vol.439 , Issue.7077 , pp. 682-687
    • Barber, D.L.1    Wherry, E.J.2    Masopust, D.3    Zhu, B.4    Allison, J.P.5    Sharpe, A.H.6    Freeman, G.J.7    Ahmed, R.8
  • 30
    • 66149123225 scopus 로고    scopus 로고
    • Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection
    • Blattman J. N., Wherry E. J., Ha S. J., Van Der Most R. G., Ahmed R., Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection Journal of Virology 2009 83 9 4386 4394
    • (2009) Journal of Virology , vol.83 , Issue.9 , pp. 4386-4394
    • Blattman, J.N.1    Wherry, E.J.2    Ha, S.J.3    Van Der Most, R.G.4    Ahmed, R.5
  • 35
    • 34249711903 scopus 로고    scopus 로고
    • + T-cell exhaustion in typical progressors but not in long-term nonprogressors
    • DOI 10.1182/blood-2006-09-044826
    • Zhang J. Y., Zhang Z., Wang X., Fu J. L., Yao J., Jiao Y., Chen L., Zhang H., Wei J., Jin L., Shi M., Gao G. F., Wu H., Wang F. S., PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors Blood 2007 109 11 4671 4678 (Pubitemid 46827757)
    • (2007) Blood , vol.109 , Issue.11 , pp. 4671-4678
    • Zhang, J.-Y.1    Zhang, Z.2    Wang, X.3    Fu, J.-L.4    Yao, J.5    Jiao, Y.6    Chen, L.7    Zhang, H.8    Wei, J.9    Jin, L.10    Shi, M.11    Gao, G.F.12    Wu, H.13    Wang, F.-S.14
  • 37
    • 34249829895 scopus 로고    scopus 로고
    • Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination
    • DOI 10.1128/JVI.00024-07
    • Velu V., Kannanganat S., Ibegbu C., Chennareddi L., Villinger F., Freeman G. J., Ahmed R., Amara R. R., Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination Journal of Virology 2007 81 11 5819 5828 (Pubitemid 46847019)
    • (2007) Journal of Virology , vol.81 , Issue.11 , pp. 5819-5828
    • Velu, V.1    Kannanganat, S.2    Ibegbu, C.3    Chennareddi, L.4    Villinger, F.5    Freeman, G.J.6    Ahmed, R.7    Amara, R.R.8
  • 42
    • 58149339765 scopus 로고    scopus 로고
    • B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection
    • Wang X., Zhang Z., Zhang S., Fu J., Yao J., Jiao Y., Wu H., Wang F. S., B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection European Journal of Immunology 2008 38 11 3226 3236
    • (2008) European Journal of Immunology , vol.38 , Issue.11 , pp. 3226-3236
    • Wang, X.1    Zhang, Z.2    Zhang, S.3    Fu, J.4    Yao, J.5    Jiao, Y.6    Wu, H.7    Wang, F.S.8
  • 44
    • 77950611229 scopus 로고    scopus 로고
    • Institute of medicine recommendations for the prevention and control of hepatitis B and C
    • Mitchell A. E., Colvin H. M., Beasley R. P., Institute of medicine recommendations for the prevention and control of hepatitis B and C Hepatology 2010 51 3 729 733
    • (2010) Hepatology , vol.51 , Issue.3 , pp. 729-733
    • Mitchell, A.E.1    Colvin, H.M.2    Beasley, R.P.3
  • 45
    • 0037460124 scopus 로고    scopus 로고
    • Viral escape and T cell exhaustion in hepatitis C virus infection analysed using Class I peptide tetramers
    • DOI 10.1016/S0165-2478(02)00224-9, PII S0165247802002249
    • Kantzanou M., Lucas M., Barnes E., Komatsu H., Dusheiko G., Ward S., Harcourt G., Klenerman P., Viral escape and T cell exhaustion in hepatitis C virus infection analysed using Class I peptide tetramers Immunology Letters 2003 85 2 165 171 (Pubitemid 36071572)
    • (2003) Immunology Letters , vol.85 , Issue.2 , pp. 165-171
    • Kantzanou, M.1    Lucas, M.2    Barnes, E.3    Komatsu, H.4    Dusheiko, G.5    Ward, S.6    Harcourt, G.7    Klenerman, P.8
  • 48
    • 35648968689 scopus 로고    scopus 로고
    • PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients
    • DOI 10.1016/j.molimm.2007.07.038, PII S0161589007006736
    • Peng G., Li S., Wu W., Tan X., Chen Y., Chen Z., PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients Molecular Immunology 2008 45 4 963 970 (Pubitemid 350019503)
    • (2008) Molecular Immunology , vol.45 , Issue.4 , pp. 963-970
    • Peng, G.1    Li, S.2    Wu, W.3    Tan, X.4    Chen, Y.5    Chen, Z.6
  • 49
    • 33947716804 scopus 로고    scopus 로고
    • Expression of programmed-death receptor ligands 1 and 2 may contribute to the poor stimulatory potential of murine immature dendritic cells
    • DOI 10.1016/j.imbio.2007.01.004, PII S0171298507000150
    • Chen C., Qu Q. X., Huang J. A., Zhu Y. B., Ge Y., Wang Q., Zhang X. G., Expression of programmed-death receptor ligands 1 and 2 may contribute to the poor stimulatory potential of murine immature dendritic cells Immunobiology 2007 212 3 159 165 (Pubitemid 46505958)
    • (2007) Immunobiology , vol.212 , Issue.3 , pp. 159-165
    • Chen, C.1    Qu, Q.-X.2    Huang, J.-a.3    Zhu, Y.-B.4    Ge, Y.5    Wang, Q.6    Zhang, X.-G.7
  • 50
    • 33750691709 scopus 로고    scopus 로고
    • PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion
    • DOI 10.1128/JVI.01177-06
    • Urbani S., Amadei B., Tola D., Massari M., Schivazappa S., Missale G., Ferrari C., PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion Journal of Virology 2006 80 22 11398 11403 (Pubitemid 44706581)
    • (2006) Journal of Virology , vol.80 , Issue.22 , pp. 11398-11403
    • Urbani, S.1    Amadei, B.2    Tola, D.3    Massari, M.4    Schivazappa, S.5    Missale, G.6    Ferrari, C.7
  • 51
    • 33847406557 scopus 로고    scopus 로고
    • + T lymphocytes in the liver
    • Maier H., Isogawa M., Freeman G. J., Chisari F. V., PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver The Journal of Immunology 2007 178 5 2714 2720 (Pubitemid 46333147)
    • (2007) Journal of Immunology , vol.178 , Issue.5 , pp. 2714-2720
    • Maier, H.1    Isogawa, M.2    Freeman, G.J.3    Chisari, F.V.4
  • 52
    • 34548191951 scopus 로고    scopus 로고
    • + T cells associated with reversible immune dysfunction
    • DOI 10.1128/JVI.00409-07
    • Golden-Mason L., Palmer B., Klarquist J., Mengshol J. A., Castelblanco N., Rosen H. R., Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction Journal of Virology 2007 81 17 9249 9258 (Pubitemid 47311467)
    • (2007) Journal of Virology , vol.81 , Issue.17 , pp. 9249-9258
    • Golden-Mason, L.1    Palmer, B.2    Klarquist, J.3    Mengshol, J.A.4    Castelblanco, N.5    Rosen, H.R.6
  • 54
    • 60049096721 scopus 로고    scopus 로고
    • Level of herpes simplex virus type 1 latency correlates with severity of corneal scarring and exhaustion of CD8+ T cells in trigeminal ganglia of latently infected mice
    • Mott K. R., Bresee C. J., Allen S. J., BenMohamed L., Wechsler S. L., Ghiasi H., Level of herpes simplex virus type 1 latency correlates with severity of corneal scarring and exhaustion of CD8+ T cells in trigeminal ganglia of latently infected mice Journal of Virology 2009 83 5 2246 2254
    • (2009) Journal of Virology , vol.83 , Issue.5 , pp. 2246-2254
    • Mott, K.R.1    Bresee, C.J.2    Allen, S.J.3    Benmohamed, L.4    Wechsler, S.L.5    Ghiasi, H.6
  • 55
    • 78049511214 scopus 로고    scopus 로고
    • Immunization with different viral antigens alters the pattern of T cell exhaustion and latency in herpes simplex virus type 1-infected mice
    • Allen S. J., Mott K. R., Zandian M., Ghiasi H., Immunization with different viral antigens alters the pattern of T cell exhaustion and latency in herpes simplex virus type 1-infected mice Journal of Virology 2010 84 23 12315 12324
    • (2010) Journal of Virology , vol.84 , Issue.23 , pp. 12315-12324
    • Allen, S.J.1    Mott, K.R.2    Zandian, M.3    Ghiasi, H.4
  • 57
    • 73949138471 scopus 로고    scopus 로고
    • Early CD4+ T cell help prevents partial CD8+ T cell exhaustion and promotes maintenance of herpes simplex virus 1 latency
    • Frank G. M., Lepisto A. J., Freeman M. L., Sheridan B. S., Cherpes T. L., Hendricks R. L., Early CD4+ T cell help prevents partial CD8+ T cell exhaustion and promotes maintenance of herpes simplex virus 1 latency The Journal of Immunology 2010 184 1 277 286
    • (2010) The Journal of Immunology , vol.184 , Issue.1 , pp. 277-286
    • Frank, G.M.1    Lepisto, A.J.2    Freeman, M.L.3    Sheridan, B.S.4    Cherpes, T.L.5    Hendricks, R.L.6
  • 59
    • 33644558718 scopus 로고    scopus 로고
    • Expression of B7-H1 on gastric epithelial cells: Its potential role in regulating T cells during Helicobacter pylori infection
    • Das S., Suarez G., Beswick E. J., Sierra J. C., Graham D. Y., Reyes V. E., Expression of B7-H1 on gastric epithelial cells: its potential role in regulating T cells during Helicobacter pylori infection The Journal of Immunology 2006 176 5 3000 3009
    • (2006) The Journal of Immunology , vol.176 , Issue.5 , pp. 3000-3009
    • Das, S.1    Suarez, G.2    Beswick, E.J.3    Sierra, J.C.4    Graham, D.Y.5    Reyes, V.E.6
  • 61
    • 79960133308 scopus 로고    scopus 로고
    • Expression of CD25high regulatory T cells and PD-1 in gastric infiltrating CD8+ T lymphocytes in patients with Helicobacter pylori infection
    • Wu Y.-Y., Chen J.-H., Kao J.-T., Liu K.-C., Lai C.-H., Wang Y.-M., Hsieh C.-T., Tzen J. T.C., Hsu P.-N., Expression of CD25high regulatory T cells and PD-1 in gastric infiltrating CD8+ T lymphocytes in patients with Helicobacter pylori infection Clinical and Vaccine Immunology 2011 18 7 1198 1201
    • (2011) Clinical and Vaccine Immunology , vol.18 , Issue.7 , pp. 1198-1201
    • Wu, Y.-Y.1    Chen, J.-H.2    Kao, J.-T.3    Liu, K.-C.4    Lai, C.-H.5    Wang, Y.-M.6    Hsieh, C.-T.7    Tzen, J.T.C.8    Hsu, P.-N.9
  • 63
    • 67249117672 scopus 로고    scopus 로고
    • B7-H1 blockade increases survival of dysfunctional CD8+ T cells and confers protection against Leishmania donovaniinfections
    • Joshi T., Rodriguez S., Perovic V., Cockburn I. A., Stger S., B7-H1 blockade increases survival of dysfunctional CD8+ T cells and confers protection against Leishmania donovaniinfections PLoS Pathogens 2009 5 5
    • (2009) PLoS Pathogens , vol.5 , Issue.5
    • Joshi, T.1    Rodriguez, S.2    Perovic, V.3    Cockburn, I.A.4    Stger, S.5
  • 65
    • 3142750528 scopus 로고    scopus 로고
    • Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages
    • Smith P., Walsh C. M., Mangan N. E., Fallon R. E., Sayers J. R., McKenzie A. N. J., Fallon P. G., Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages The Journal of Immunology 2004 173 2 1240 1248 (Pubitemid 38924302)
    • (2004) Journal of Immunology , vol.173 , Issue.2 , pp. 1240-1248
    • Smith, P.1    Walsh, C.M.2    Mangan, N.E.3    Fallon, R.E.4    Sayers, J.R.5    McKenzie, A.N.J.6    Fallon, P.G.7
  • 66
    • 17144409086 scopus 로고    scopus 로고
    • PD-L2+ dendritic cells and PD-1+ CD4+ T cells in schistosomiasis correlate with morbidity
    • DOI 10.1111/j.1365-3024.2005.00742.x
    • Colley D. G., Sasser L. E., Reed A. M., PD-L2+ dendritic cells and PD-1+ CD4+ T cells in schistosomiasis correlate with morbidity Parasite Immunology 2005 27 1-2 45 53 (Pubitemid 40524992)
    • (2005) Parasite Immunology , vol.27 , Issue.1-2 , pp. 45-53
    • Colley, D.G.1    Sasser, L.E.2    Reed, A.M.3
  • 69
    • 79953063507 scopus 로고    scopus 로고
    • Enhancement of vaccine-induced primary and memory CD8+ t-cell responses by soluble PD-1
    • Song M. -Y., Park S. -H., Nam H. J., Choi D. -H., Sung Y. -C., Enhancement of vaccine-induced primary and memory CD8+ t-cell responses by soluble PD-1 The Journal of Immunotherapy 2011 34 3 297 306
    • (2011) The Journal of Immunotherapy , vol.34 , Issue.3 , pp. 297-306
    • Song, M.-Y.1    Park, S.-H.2    Nam, H.J.3    Choi, D.-H.4    Sung, Y.-C.5
  • 73
    • 49649114804 scopus 로고    scopus 로고
    • Phase i safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
    • Berger R., Rotem-Yehudar R., Slama G., Landes S., Kneller A., Leiba M., Koren-Michowitz M., Shimoni A., Nagler A., Phase i safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies Clinical Cancer Research 2008 14 10 3044 3051
    • (2008) Clinical Cancer Research , vol.14 , Issue.10 , pp. 3044-3051
    • Berger, R.1    Rotem-Yehudar, R.2    Slama, G.3    Landes, S.4    Kneller, A.5    Leiba, M.6    Koren-Michowitz, M.7    Shimoni, A.8    Nagler, A.9
  • 79
    • 79251578015 scopus 로고    scopus 로고
    • CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition
    • Barber D. L., Mayer-Barber K. D., Feng C. G., Sharpe A. H., Sher A., CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition The Journal of Immunology 2011 186 3 1598 1607
    • (2011) The Journal of Immunology , vol.186 , Issue.3 , pp. 1598-1607
    • Barber, D.L.1    Mayer-Barber, K.D.2    Feng, C.G.3    Sharpe, A.H.4    Sher, A.5


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