-
1
-
-
34848831575
-
The B7 family and cancer therapy: Costimulation and coinhibition
-
DOI 10.1158/1078-0432.CCR-07-1030
-
Zang X., Allison J. P., The B7 family and cancer therapy: costimulation and coinhibition Clinical Cancer Research 2007 13 18, part 1 5271 5279 (Pubitemid 47510350)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.18
, pp. 5271-5279
-
-
Zang, X.1
Allison, J.P.2
-
2
-
-
0026700235
-
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
-
Ishida Y., Agata Y., Shibahara K., Honjo T., Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death The EMBO Journal 1992 11 11 3887 3895
-
(1992)
The EMBO Journal
, vol.11
, Issue.11
, pp. 3887-3895
-
-
Ishida, Y.1
Agata, Y.2
Shibahara, K.3
Honjo, T.4
-
3
-
-
0030005099
-
Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes
-
Agata Y., Kawasaki A., Nishimura H., Ishida Y., Tsubata T., Yagita H., Honjo T., Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes International Immunology 1996 8 5 765 772 (Pubitemid 26148299)
-
(1996)
International Immunology
, vol.8
, Issue.5
, pp. 765-772
-
-
Agata, Y.1
Kawasaki, A.2
Nishimura, H.3
Ishida, Y.4
Tsubata, T.5
Yagita, H.6
Honjo, T.7
-
4
-
-
0031562690
-
Activation-induced expression of human programmed death-1 gene in T- lymphocytes
-
DOI 10.1006/excr.1997.3493
-
Vibhakar R., Juan G., Traganos F., Darzynkiewicz Z., Finger L. R., Activation-induced expression of human programmed death-1 gene in T- lymphocytes Experimental Cell Research 1997 232 1 25 28 (Pubitemid 27172215)
-
(1997)
Experimental Cell Research
, vol.232
, Issue.1
, pp. 25-28
-
-
Vibhakar, R.1
Juan, G.2
Traganos, F.3
Darzynkiewicz, Z.4
Finger, L.R.5
-
5
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman G. J., Long A. J., Iwai Y., Bourque K., Chernova T., Nishimura H., Fitz L. J., Malenkovich N., Okazaki T., Byrne M. C., Horton H. F., Fouser L., Carter L., Ling V., Bowman M. R., Carreno B. M., Collins M., Wood C. R., Honjo T., Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation The Journal of Experimental Medicine 2000 192 7 1027 1034
-
(2000)
The Journal of Experimental Medicine
, vol.192
, Issue.7
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
Fitz, L.J.7
Malenkovich, N.8
Okazaki, T.9
Byrne, M.C.10
Horton, H.F.11
Fouser, L.12
Carter, L.13
Ling, V.14
Bowman, M.R.15
Carreno, B.M.16
Collins, M.17
Wood, C.R.18
Honjo, T.19
-
6
-
-
58149314579
-
NFATc1 regulates PD-1 expression upon T cell activation
-
Oestreich K. J., Yoon H., Ahmed R., Boss J. M., NFATc1 regulates PD-1 expression upon T cell activation The Journal of Immunology 2008 181 7 4832 4839
-
(2008)
The Journal of Immunology
, vol.181
, Issue.7
, pp. 4832-4839
-
-
Oestreich, K.J.1
Yoon, H.2
Ahmed, R.3
Boss, J.M.4
-
7
-
-
79959375167
-
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection
-
Kao C., Oestreich K. J., Paley M. A., Crawford A., Angelosanto J. M., Ali M.-A. A., Intlekofer A. M., Boss J. M., Reiner S. L., Weinmann A. S., Wherry E. J., Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection Nature Immunology 2011 12 7 663 671
-
(2011)
Nature Immunology
, vol.12
, Issue.7
, pp. 663-671
-
-
Kao, C.1
Oestreich, K.J.2
Paley, M.A.3
Crawford, A.4
Angelosanto, J.M.5
Ali, M.-A.A.6
Intlekofer, A.M.7
Boss, J.M.8
Reiner, S.L.9
Weinmann, A.S.10
Wherry, E.J.11
-
8
-
-
0032736029
-
B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
-
Dong H., Zhu G., Tamada K., Chen L., B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion Nature Medicine 1999 5 12 1365 1369
-
(1999)
Nature Medicine
, vol.5
, Issue.12
, pp. 1365-1369
-
-
Dong, H.1
Zhu, G.2
Tamada, K.3
Chen, L.4
-
9
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
DOI 10.1038/85330
-
Latchman Y., Wood C. R., Chernova T., Chaudhary D., Borde M., Chernova I., Iwai Y., Long A. J., Brown J. A., Nunes R., Greenfield E. A., Bourque K., Boussiotis V. A., Carter L. L., Carreno B. M., Malenkovich N., Nishimura H., Okazaki T., Honjo T., Sharpe A. H., Freeman G. J., PD-L2 is a second ligand for PD-1 and inhibits T cell activation Nature Immunology 2001 2 3 261 268 (Pubitemid 33706004)
-
(2001)
Nature Immunology
, vol.2
, Issue.3
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
Chaudhary, D.4
Borde, M.5
Chernova, I.6
Iwai, Y.7
Long, A.J.8
Brown, J.A.9
Nunes, R.10
Greenfield, E.A.11
Bourque, K.12
Boussiotis, V.A.13
Carter, L.L.14
Carreno, B.M.15
Malenkovich, N.16
Nishimura, H.17
Okazaki, T.18
Honjo, T.19
Sharpe, A.H.20
Freeman, G.J.21
more..
-
10
-
-
0035794314
-
B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
-
DOI 10.1084/jem.193.7.839
-
Tseng S. Y., Otsuji M., Gorski K., Huang X., Slansky J. E., Pai S. I., Shalabi A., Shin T., Pardoll D. M., Tsuchiya H., B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells The Journal of Experimental Medicine 2001 193 7 839 845 (Pubitemid 32524533)
-
(2001)
Journal of Experimental Medicine
, vol.193
, Issue.7
, pp. 839-845
-
-
Tseng, S.-Y.1
Otsuji, M.2
Gorski, K.3
Huang, X.4
Slansky, J.E.5
Pai, S.I.6
Shalabi, A.7
Shin, T.8
Pardoll, D.M.9
Tsuchiya, H.10
-
11
-
-
0036207926
-
+ T cells and is overcome by IL-2
-
DOI 10.1002/1521-4141(200203)32:3<634::AID-IMMU634>3.0.CO;2-9
-
Carter L. L., Fouser L. A., Jussif J., Fitz L., Deng B., Wood C. R., Collins M., Honjo T., Freeman G. J., Carreno B. M., PD-1:PD-L inhibitory pathway affects both CD4+ and CD4+ T cells and is overcome by IL-2 European Journal of Immunology 2002 32 3 634 643 (Pubitemid 34257540)
-
(2002)
European Journal of Immunology
, vol.32
, Issue.3
, pp. 634-643
-
-
Carter, L.L.1
Fouser, L.A.2
Jussif, J.3
Fitz, L.4
Deng, B.5
Wood, C.R.6
Collins, M.7
Honjo, T.8
Freeman, G.J.9
Carreno, B.M.10
-
12
-
-
0037111483
-
Expression of programmed death 1 ligands by murine T cells and APC
-
Yamazaki T., Akiba H., Iwai H., Matsuda H., Aoki M., Tanno Y., Shin T., Tsuchiya H., Pardoll D. M., Okumura K., Azuma M., Yagita H., Expression of programmed death 1 ligands by murine T cells and APC The Journal of Immunology 2002 169 10 5538 5545 (Pubitemid 35291652)
-
(2002)
Journal of Immunology
, vol.169
, Issue.10
, pp. 5538-5545
-
-
Yamazaki, T.1
Akiba, H.2
Iwai, H.3
Matsuda, H.4
Aoki, M.5
Tanno, Y.6
Shin, T.7
Tsuchiya, H.8
Pardoll, D.M.9
Okumura, K.10
Azuma, M.11
Yagita, H.12
-
13
-
-
31444451661
-
Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-induced upregulation of B7-H1 (CD274)
-
DOI 10.1016/j.febslet.2005.12.093, PII S0014579306000044
-
Lee S. J., Jang B. C., Lee S. W., Yang Y. I., Suh S. I., Park Y. M., Oh S., Shin J. G., Yao S., Chen L., Choi I. H., Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN- -induced upregulation of B7-H1 (CD274) FEBS Letters 2006 580 3 755 762 (Pubitemid 43152293)
-
(2006)
FEBS Letters
, vol.580
, Issue.3
, pp. 755-762
-
-
Lee, S.-J.1
Jang, B.-C.2
Lee, S.-W.3
Yang, Y.-I.4
Suh, S.-I.5
Park, Y.-M.6
Oh, S.7
Shin, J.-G.8
Yao, S.9
Chen, L.10
Choi, I.-H.11
-
15
-
-
0037307930
-
Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production
-
Brown J. A., Dorfman D. M., Ma F. R., Sullivan E. L., Munoz O., Wood C. R., Greenfield E. A., Freeman G. J., Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production The Journal of Immunology 2003 170 3 1257 1266 (Pubitemid 36139491)
-
(2003)
Journal of Immunology
, vol.170
, Issue.3
, pp. 1257-1266
-
-
Brown, J.A.1
Dorfman, D.M.2
Ma, F.-R.3
Sullivan, E.L.4
Munoz, O.5
Wood, C.R.6
Greenfield, E.A.7
Freeman, G.J.8
-
16
-
-
0035923535
-
PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine
-
DOI 10.1073/pnas.231486598
-
Okazaki T., Maeda A., Nishimura H., Kurosaki T., Honjo T., PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine Proceedings of the National Academy of Sciences of the United States of America 2001 98 24 13866 13871 (Pubitemid 33115990)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.24
, pp. 13866-13871
-
-
Okazaki, T.1
Maeda, A.2
Nishimura, H.3
Kurosaki, T.4
Honjo, T.5
-
17
-
-
3142688997
-
SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation
-
Chemnitz J. M., Parry R. V., Nichols K. E., June C. H., Riley J. L., SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation The Journal of Immunology 2004 173 2 945 954 (Pubitemid 38924267)
-
(2004)
Journal of Immunology
, vol.173
, Issue.2
, pp. 945-954
-
-
Chemnitz, J.M.1
Parry, R.V.2
Nichols, K.E.3
June, C.H.4
Riley, J.L.5
-
18
-
-
4444317516
-
PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3 signalosome and downstream signaling to PKC
-
DOI 10.1016/j.febslet.2004.07.083, PII S0014579304009779
-
Sheppard K. A., Fitz L. J., Lee J. M., Benander C., George J. A., Wooters J., Qiu Y., Jussif J. M., Carter L. L., Wood C. R., Chaudhary D., PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3 signalosome and downstream signaling to PKCθ FEBS Letters 2004 574 1-3 37 41 (Pubitemid 39200891)
-
(2004)
FEBS Letters
, vol.574
, Issue.1-3
, pp. 37-41
-
-
Sheppard, K.-A.1
Fitz, L.J.2
Lee, J.M.3
Benander, C.4
George, J.A.5
Wooters, J.6
Qiu, Y.7
Jussif, J.M.8
Carter, L.L.9
Wood, C.R.10
Chaudhary, D.11
-
19
-
-
27144496045
-
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms
-
DOI 10.1128/MCB.25.21.9543-9553.2005
-
Parry R. V., Chemnitz J. M., Frauwirth K. A., Lanfranco A. R., Braunstein I., Kobayashi S. V., Linsley P. S., Thompson C. B., Riley J. L., CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms Molecular and Cellular Biology 2005 25 21 9543 9553 (Pubitemid 41507854)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.21
, pp. 9543-9553
-
-
Parry, R.V.1
Chemnitz, J.M.2
Frauwirth, K.A.3
Lanfranco, A.R.4
Braunstein, I.5
Kobayashi, S.V.6
Linsley, P.S.7
Thompson, C.B.8
Riley, J.L.9
-
20
-
-
34447646310
-
Programmed Death-1 Ligand 1 Interacts Specifically with the B7-1 Costimulatory Molecule to Inhibit T Cell Responses
-
DOI 10.1016/j.immuni.2007.05.016, PII S1074761307003287
-
Butte M. J., Keir M. E., Phamduy T. B., Sharpe A. H., Freeman G. J., Programmed Death-1 Ligand 1 Interacts Specifically with the B7-1 Costimulatory Molecule to Inhibit T Cell Responses Immunity 2007 27 1 111 122 (Pubitemid 47089023)
-
(2007)
Immunity
, vol.27
, Issue.1
, pp. 111-122
-
-
Butte, M.J.1
Keir, M.E.2
Phamduy, T.B.3
Sharpe, A.H.4
Freeman, G.J.5
-
21
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
DOI 10.1016/S1074-7613(00)80089-8
-
Nishimura H., Nose M., Hiai H., Minato N., Honjo T., Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor Immunity 1999 11 2 141 151 (Pubitemid 29428807)
-
(1999)
Immunity
, vol.11
, Issue.2
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
22
-
-
0035846991
-
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice
-
DOI 10.1126/science.291.5502.319
-
Nishimura H., Okazaki T., Tanaka Y., Nakatani K., Hara M., Matsumori A., Sasayama S., Mizoguchi A., Hiai H., Minato N., Honjo T., Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice Science 2001 291 5502 319 322 (Pubitemid 32096320)
-
(2001)
Science
, vol.291
, Issue.5502
, pp. 319-322
-
-
Nishimura, H.1
Okazaki, T.2
Tanaka, Y.3
Nakatani, K.4
Hara, M.5
Matsumori, A.6
Sasayama, S.7
Mizoguchi, A.8
Hiai, H.9
Minato, N.10
Honjo, T.11
-
23
-
-
0037815272
-
PD-1 inhibits antiviral immunity at the effector phase in the liver
-
DOI 10.1084/jem.20022235
-
Iwai Y., Terawaki S., Ikegawa M., Okazaki T., Honjo T., PD-1 inhibits antiviral immunity at the effector phase in the liver The Journal of Experimental Medicine 2003 198 1 39 50 (Pubitemid 36870184)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.1
, pp. 39-50
-
-
Iwai, Y.1
Terawaki, S.2
Ikegawa, M.3
Okazaki, T.4
Honjo, T.5
-
24
-
-
70350433514
-
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
-
Fife B. T., Pauken K. E., Eagar T. N., Obu T., Wu J., Tang Q., Azuma M., Krummel M. F., Bluestone J. A., Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal Nature Immunology 2009 10 11 1185 1192
-
(2009)
Nature Immunology
, vol.10
, Issue.11
, pp. 1185-1192
-
-
Fife, B.T.1
Pauken, K.E.2
Eagar, T.N.3
Obu, T.4
Wu, J.5
Tang, Q.6
Azuma, M.7
Krummel, M.F.8
Bluestone, J.A.9
-
25
-
-
73949088551
-
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
-
Francisco L. M., Salinas V. H., Brown K. E., Vanguri V. K., Freeman G. J., Kuchroo V. K., Sharpe A. H., PD-L1 regulates the development, maintenance, and function of induced regulatory T cells The Journal of Experimental Medicine 2009 206 13 3015 3029
-
(2009)
The Journal of Experimental Medicine
, vol.206
, Issue.13
, pp. 3015-3029
-
-
Francisco, L.M.1
Salinas, V.H.2
Brown, K.E.3
Vanguri, V.K.4
Freeman, G.J.5
Kuchroo, V.K.6
Sharpe, A.H.7
-
26
-
-
0032416085
-
Viral immune evasion due to persistence of activated T cells without effector function
-
DOI 10.1084/jem.188.12.2205
-
Zajac A. J., Blattman J. N., Murali-Krishna K., Sourdive D. J. D., Suresh M., Altman J. D., Ahmed R., Viral immune evasion due to persistence of activated T cells without effector function The Journal of Experimental Medicine 1998 188 12 2205 2213 (Pubitemid 29028493)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.12
, pp. 2205-2213
-
-
Zajac, A.J.1
Blattman, J.N.2
Murali-Krishna, K.3
Sourdive, D.J.D.4
Suresh, M.5
Altman, J.D.6
Ahmed, R.7
-
27
-
-
0032482176
-
Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes
-
DOI 10.1084/jem.187.9.1383
-
Gallimore A., Glithero A., Godkin A., Tissot A. C., Plckthun A., Elliott T., Hengartner H., Zinkernagel R., Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes The Journal of Experimental Medicine 1998 187 9 1383 1393 (Pubitemid 28215398)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.9
, pp. 1383-1393
-
-
Gallimore, A.1
Glithero, A.2
Godkin, A.3
Tissot, A.C.4
Pluckthun, A.5
Elliott, T.6
Hengartner, H.7
Zinkernagel, R.8
-
28
-
-
35349014587
-
+ T Cell Exhaustion during Chronic Viral Infection
-
DOI 10.1016/j.immuni.2007.09.006, PII S1074761307004542
-
Wherry E. J., Ha S. J., Kaech S. M., Haining W. N., Sarkar S., Kalia V., Subramaniam S., Blattman J. N., Barber D. L., Ahmed R., Molecular signature of CD8+ T cell exhaustion during chronic viral infection Immunity 2007 27 4 670 684 (Pubitemid 47615511)
-
(2007)
Immunity
, vol.27
, Issue.4
, pp. 670-684
-
-
Wherry, E.J.1
Ha, S.-J.2
Kaech, S.M.3
Haining, W.N.4
Sarkar, S.5
Kalia, V.6
Subramaniam, S.7
Blattman, J.N.8
Barber, D.L.9
Ahmed, R.10
-
29
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
DOI 10.1038/nature04444, PII NATURE04444
-
Barber D. L., Wherry E. J., Masopust D., Zhu B., Allison J. P., Sharpe A. H., Freeman G. J., Ahmed R., Restoring function in exhausted CD8 T cells during chronic viral infection Nature 2006 439 7077 682 687 (Pubitemid 43237609)
-
(2006)
Nature
, vol.439
, Issue.7077
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
30
-
-
66149123225
-
Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection
-
Blattman J. N., Wherry E. J., Ha S. J., Van Der Most R. G., Ahmed R., Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection Journal of Virology 2009 83 9 4386 4394
-
(2009)
Journal of Virology
, vol.83
, Issue.9
, pp. 4386-4394
-
-
Blattman, J.N.1
Wherry, E.J.2
Ha, S.J.3
Van Der Most, R.G.4
Ahmed, R.5
-
31
-
-
54449088740
-
Selective expansion of a subset of exhausted CD8 T cells by PD-L1 blockade
-
Blackburn S. D., Shin H., Freeman G. J., Wherry E. J., Selective expansion of a subset of exhausted CD8 T cells by PD-L1 blockade Proceedings of the National Academy of Sciences of the United States of America 2008 105 39 15016 15021
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.39
, pp. 15016-15021
-
-
Blackburn, S.D.1
Shin, H.2
Freeman, G.J.3
Wherry, E.J.4
-
33
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
DOI 10.1038/nature05115, PII NATURE05115
-
Day C. L., Kaufmann D. E., Kiepiela P., Brown J. A., Moodley E. S., Reddy S., Mackey E. W., Miller J. D., Leslie A. J., DePierres C., Mncube Z., Duraiswamy J., Zhu B., Eichbaum Q., Altfeld M., Wherry E. J., Coovadia H. M., Goulder P. J. R., Klenerman P., Ahmed R., Freeman G. J., Walker B. D., PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression Nature 2006 443 7109 350 354 (Pubitemid 44435155)
-
(2006)
Nature
, vol.443
, Issue.7109
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
Reddy, S.6
Mackey, E.W.7
Miller, J.D.8
Leslie, A.J.9
DePierres, C.10
Mncube, Z.11
Duraiswamy, J.12
Zhu, B.13
Eichbaum, Q.14
Altfeld, M.15
Wherry, E.J.16
Coovadia, H.M.17
Goulder, P.J.R.18
Klenerman, P.19
Ahmed, R.20
Freeman, G.J.21
Walker, B.D.22
more..
-
34
-
-
33749009709
-
+ T cells leads to reversible immune dysfunction
-
DOI 10.1038/nm1482, PII NM1482
-
Trautmann L., Janbazian L., Chomont N., Said E. A., Gimmig S., Bessette B., Boulassel M. R., Delwart E., Sepulveda H., Balderas R. S., Routy J. P., Haddad E. K., Sekaly R. P., Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction Nature Medicine 2006 12 10 1198 1202 (Pubitemid 44527357)
-
(2006)
Nature Medicine
, vol.12
, Issue.10
, pp. 1198-1202
-
-
Trautmann, L.1
Janbazian, L.2
Chomont, N.3
Said, E.A.4
Gimmig, S.5
Bessette, B.6
Boulassel, M.-R.7
Delwart, E.8
Sepulveda, H.9
Balderas, R.S.10
Routy, J.-P.11
Haddad, E.K.12
Sekaly, R.-P.13
-
35
-
-
34249711903
-
+ T-cell exhaustion in typical progressors but not in long-term nonprogressors
-
DOI 10.1182/blood-2006-09-044826
-
Zhang J. Y., Zhang Z., Wang X., Fu J. L., Yao J., Jiao Y., Chen L., Zhang H., Wei J., Jin L., Shi M., Gao G. F., Wu H., Wang F. S., PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors Blood 2007 109 11 4671 4678 (Pubitemid 46827757)
-
(2007)
Blood
, vol.109
, Issue.11
, pp. 4671-4678
-
-
Zhang, J.-Y.1
Zhang, Z.2
Wang, X.3
Fu, J.-L.4
Yao, J.5
Jiao, Y.6
Chen, L.7
Zhang, H.8
Wei, J.9
Jin, L.10
Shi, M.11
Gao, G.F.12
Wu, H.13
Wang, F.-S.14
-
36
-
-
77957781776
-
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
-
Quigley M., Pereyra F., Nilsson B., Porichis F., Fonseca C., Eichbaum Q., Julg B., Jesneck J. L., Brosnahan K., Imam S., Russell K., Toth I., Piechocka-Trocha A., Dolfi D., Angelosanto J., Crawford A., Shin H., Kwon D. S., Zupkosky J., Francisco L., Freeman G. J., Wherry E. J., Kaufmann D. E., Walker B. D., Ebert B., Haining W. N., Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF Nature Medicine 2010 16 10 1147 1151
-
(2010)
Nature Medicine
, vol.16
, Issue.10
, pp. 1147-1151
-
-
Quigley, M.1
Pereyra, F.2
Nilsson, B.3
Porichis, F.4
Fonseca, C.5
Eichbaum, Q.6
Julg, B.7
Jesneck, J.L.8
Brosnahan, K.9
Imam, S.10
Russell, K.11
Toth, I.12
Piechocka-Trocha, A.13
Dolfi, D.14
Angelosanto, J.15
Crawford, A.16
Shin, H.17
Kwon, D.S.18
Zupkosky, J.19
Francisco, L.20
Freeman, G.J.21
Wherry, E.J.22
Kaufmann, D.E.23
Walker, B.D.24
Ebert, B.25
Haining, W.N.26
more..
-
37
-
-
34249829895
-
Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination
-
DOI 10.1128/JVI.00024-07
-
Velu V., Kannanganat S., Ibegbu C., Chennareddi L., Villinger F., Freeman G. J., Ahmed R., Amara R. R., Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination Journal of Virology 2007 81 11 5819 5828 (Pubitemid 46847019)
-
(2007)
Journal of Virology
, vol.81
, Issue.11
, pp. 5819-5828
-
-
Velu, V.1
Kannanganat, S.2
Ibegbu, C.3
Chennareddi, L.4
Villinger, F.5
Freeman, G.J.6
Ahmed, R.7
Amara, R.R.8
-
38
-
-
34547931898
-
+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection
-
DOI 10.1182/blood-2007-01-069112
-
Petrovas C., Price D. A., Mattapallil J., Ambrozak D. R., Geldmacher C., Cecchinato V., Vaccari M., Tryniszewska E., Gostick E., Roederer M., Douek D. C., Morgan S. H., Davis S. J., Franchini G., Koup R. A., SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection Blood 2007 110 3 928 936 (Pubitemid 47267431)
-
(2007)
Blood
, vol.110
, Issue.3
, pp. 928-936
-
-
Petrovas, C.1
Price, D.A.2
Mattapallil, J.3
Ambrozak, D.R.4
Geldmacher, C.5
Cecchinato, V.6
Vaccari, M.7
Tryniszewska, E.8
Gostick, E.9
Roederer, M.10
Douek, D.C.11
Morgan, S.H.12
Davis, S.J.13
Franchini, G.14
Koup, R.A.15
-
39
-
-
34548637484
-
Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction
-
D'Souza M., Fontenot A. P., Mack D. G., Lozupone C., Dillon S., Meditz A., Wilson C. C., Connick E., Palmer B. E., Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction The Journal of Immunology 2007 179 3 1979 1987
-
(2007)
The Journal of Immunology
, vol.179
, Issue.3
, pp. 1979-1987
-
-
D'Souza, M.1
Fontenot, A.P.2
Mack, D.G.3
Lozupone, C.4
Dillon, S.5
Meditz, A.6
Wilson, C.C.7
Connick, E.8
Palmer, B.E.9
-
40
-
-
77950525439
-
Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection
-
Said E. A., Dupuy F. P., Trautmann L., Zhang Y., Shi Y., El-Far M., Hill B. J., Noto A., Ancuta P., Peretz Y., Fonseca S. G., Van Grevenynghe J., Boulassel M. R., Bruneau J., Shoukry N. H., Routy J. P., Douek D. C., Haddad E. K., Sekaly R. P., Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection Nature Medicine 2010 16 4 452 459
-
(2010)
Nature Medicine
, vol.16
, Issue.4
, pp. 452-459
-
-
Said, E.A.1
Dupuy, F.P.2
Trautmann, L.3
Zhang, Y.4
Shi, Y.5
El-Far, M.6
Hill, B.J.7
Noto, A.8
Ancuta, P.9
Peretz, Y.10
Fonseca, S.G.11
Van Grevenynghe, J.12
Boulassel, M.R.13
Bruneau, J.14
Shoukry, N.H.15
Routy, J.P.16
Douek, D.C.17
Haddad, E.K.18
Sekaly, R.P.19
-
41
-
-
0038784354
-
B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression
-
DOI 10.1182/blood-2002-10-3065
-
Trabattoni D., Saresella M., Biasin M., Boasso A., Piacentini L., Ferrante P., Dong H., Maserati R., Shearer G. M., Chen L., Clerici M., B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression Blood 2003 101 7 2514 2520 (Pubitemid 36857606)
-
(2003)
Blood
, vol.101
, Issue.7
, pp. 2514-2520
-
-
Trabattoni, D.1
Saresella, M.2
Biasin, M.3
Boasso, A.4
Piacentini, L.5
Ferrante, P.6
Dong, H.7
Maserati, R.8
Shearer, G.M.9
Chen, L.10
Clerici, M.11
-
42
-
-
58149339765
-
B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection
-
Wang X., Zhang Z., Zhang S., Fu J., Yao J., Jiao Y., Wu H., Wang F. S., B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection European Journal of Immunology 2008 38 11 3226 3236
-
(2008)
European Journal of Immunology
, vol.38
, Issue.11
, pp. 3226-3236
-
-
Wang, X.1
Zhang, Z.2
Zhang, S.3
Fu, J.4
Yao, J.5
Jiao, Y.6
Wu, H.7
Wang, F.S.8
-
43
-
-
78851469796
-
Expression of PD-L1 and PD-L2 on human macrophages is up-regulated by HIV-1 and differentially modulated by IL-10
-
Rodrguez-Garca M., Porichis F., de Jong O. G., Levi K., Diefenbach T. J., Lifson J. D., Freeman G. J., Walker B. D., Kaufmann D. E., Kavanagh D. G., Expression of PD-L1 and PD-L2 on human macrophages is up-regulated by HIV-1 and differentially modulated by IL-10 Journal of Leukocyte Biology 2011 89 4 507 515
-
(2011)
Journal of Leukocyte Biology
, vol.89
, Issue.4
, pp. 507-515
-
-
Rodrguez-Garca, M.1
Porichis, F.2
De Jong, O.G.3
Levi, K.4
Diefenbach, T.J.5
Lifson, J.D.6
Freeman, G.J.7
Walker, B.D.8
Kaufmann, D.E.9
Kavanagh, D.G.10
-
44
-
-
77950611229
-
Institute of medicine recommendations for the prevention and control of hepatitis B and C
-
Mitchell A. E., Colvin H. M., Beasley R. P., Institute of medicine recommendations for the prevention and control of hepatitis B and C Hepatology 2010 51 3 729 733
-
(2010)
Hepatology
, vol.51
, Issue.3
, pp. 729-733
-
-
Mitchell, A.E.1
Colvin, H.M.2
Beasley, R.P.3
-
45
-
-
0037460124
-
Viral escape and T cell exhaustion in hepatitis C virus infection analysed using Class I peptide tetramers
-
DOI 10.1016/S0165-2478(02)00224-9, PII S0165247802002249
-
Kantzanou M., Lucas M., Barnes E., Komatsu H., Dusheiko G., Ward S., Harcourt G., Klenerman P., Viral escape and T cell exhaustion in hepatitis C virus infection analysed using Class I peptide tetramers Immunology Letters 2003 85 2 165 171 (Pubitemid 36071572)
-
(2003)
Immunology Letters
, vol.85
, Issue.2
, pp. 165-171
-
-
Kantzanou, M.1
Lucas, M.2
Barnes, E.3
Komatsu, H.4
Dusheiko, G.5
Ward, S.6
Harcourt, G.7
Klenerman, P.8
-
46
-
-
0037029652
-
Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection
-
DOI 10.1084/jem.20011723
-
Reignat S., Webster G. J. M., Brown D., Ogg G. S., King A., Seneviratne S. L., Dusheiko G., Williams R., Maini M. K., Bertoletti A., Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection The Journal of Experimental Medicine 2002 195 9 1089 1101 (Pubitemid 34517136)
-
(2002)
Journal of Experimental Medicine
, vol.195
, Issue.9
, pp. 1089-1101
-
-
Reignat, S.1
Webster, G.J.M.2
Brown, D.3
Ogg, G.S.4
King, A.5
Seneviratne, S.L.6
Dusheiko, G.7
Williams, R.8
Maini, M.K.9
Bertoletti, A.10
-
47
-
-
34247117935
-
Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection
-
DOI 10.1128/JVI.02844-06
-
Boni C., Fisicaro P., Valdatta C., Amadei B., Di Vincenzo P., Giuberti T., Laccabue D., Zerbini A., Cavalli A., Missale G., Bertoletti A., Ferrari C., Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection Journal of Virology 2007 81 8 4215 4225 (Pubitemid 46586915)
-
(2007)
Journal of Virology
, vol.81
, Issue.8
, pp. 4215-4225
-
-
Boni, C.1
Fisicaro, P.2
Valdatta, C.3
Amadei, B.4
Di Vincenzo, P.5
Giuberti, T.6
Laccabue, D.7
Zerbini, A.8
Cavalli, A.9
Missale, G.10
Bertoletti, A.11
Ferrari, C.12
-
48
-
-
35648968689
-
PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients
-
DOI 10.1016/j.molimm.2007.07.038, PII S0161589007006736
-
Peng G., Li S., Wu W., Tan X., Chen Y., Chen Z., PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients Molecular Immunology 2008 45 4 963 970 (Pubitemid 350019503)
-
(2008)
Molecular Immunology
, vol.45
, Issue.4
, pp. 963-970
-
-
Peng, G.1
Li, S.2
Wu, W.3
Tan, X.4
Chen, Y.5
Chen, Z.6
-
49
-
-
33947716804
-
Expression of programmed-death receptor ligands 1 and 2 may contribute to the poor stimulatory potential of murine immature dendritic cells
-
DOI 10.1016/j.imbio.2007.01.004, PII S0171298507000150
-
Chen C., Qu Q. X., Huang J. A., Zhu Y. B., Ge Y., Wang Q., Zhang X. G., Expression of programmed-death receptor ligands 1 and 2 may contribute to the poor stimulatory potential of murine immature dendritic cells Immunobiology 2007 212 3 159 165 (Pubitemid 46505958)
-
(2007)
Immunobiology
, vol.212
, Issue.3
, pp. 159-165
-
-
Chen, C.1
Qu, Q.-X.2
Huang, J.-a.3
Zhu, Y.-B.4
Ge, Y.5
Wang, Q.6
Zhang, X.-G.7
-
50
-
-
33750691709
-
PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion
-
DOI 10.1128/JVI.01177-06
-
Urbani S., Amadei B., Tola D., Massari M., Schivazappa S., Missale G., Ferrari C., PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion Journal of Virology 2006 80 22 11398 11403 (Pubitemid 44706581)
-
(2006)
Journal of Virology
, vol.80
, Issue.22
, pp. 11398-11403
-
-
Urbani, S.1
Amadei, B.2
Tola, D.3
Massari, M.4
Schivazappa, S.5
Missale, G.6
Ferrari, C.7
-
51
-
-
33847406557
-
+ T lymphocytes in the liver
-
Maier H., Isogawa M., Freeman G. J., Chisari F. V., PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver The Journal of Immunology 2007 178 5 2714 2720 (Pubitemid 46333147)
-
(2007)
Journal of Immunology
, vol.178
, Issue.5
, pp. 2714-2720
-
-
Maier, H.1
Isogawa, M.2
Freeman, G.J.3
Chisari, F.V.4
-
52
-
-
34548191951
-
+ T cells associated with reversible immune dysfunction
-
DOI 10.1128/JVI.00409-07
-
Golden-Mason L., Palmer B., Klarquist J., Mengshol J. A., Castelblanco N., Rosen H. R., Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction Journal of Virology 2007 81 17 9249 9258 (Pubitemid 47311467)
-
(2007)
Journal of Virology
, vol.81
, Issue.17
, pp. 9249-9258
-
-
Golden-Mason, L.1
Palmer, B.2
Klarquist, J.3
Mengshol, J.A.4
Castelblanco, N.5
Rosen, H.R.6
-
53
-
-
61449181280
-
Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade
-
Nakamoto N., Cho H., Shaked A., Olthoff K., Valiga M. E., Kaminski M., Gostick E., Price D. A., Freeman G. J., Wherry E. J., Chang K. M., Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade PLoS Pathogens 2009 5 2
-
(2009)
PLoS Pathogens
, vol.5
, Issue.2
-
-
Nakamoto, N.1
Cho, H.2
Shaked, A.3
Olthoff, K.4
Valiga, M.E.5
Kaminski, M.6
Gostick, E.7
Price, D.A.8
Freeman, G.J.9
Wherry, E.J.10
Chang, K.M.11
-
54
-
-
60049096721
-
Level of herpes simplex virus type 1 latency correlates with severity of corneal scarring and exhaustion of CD8+ T cells in trigeminal ganglia of latently infected mice
-
Mott K. R., Bresee C. J., Allen S. J., BenMohamed L., Wechsler S. L., Ghiasi H., Level of herpes simplex virus type 1 latency correlates with severity of corneal scarring and exhaustion of CD8+ T cells in trigeminal ganglia of latently infected mice Journal of Virology 2009 83 5 2246 2254
-
(2009)
Journal of Virology
, vol.83
, Issue.5
, pp. 2246-2254
-
-
Mott, K.R.1
Bresee, C.J.2
Allen, S.J.3
Benmohamed, L.4
Wechsler, S.L.5
Ghiasi, H.6
-
55
-
-
78049511214
-
Immunization with different viral antigens alters the pattern of T cell exhaustion and latency in herpes simplex virus type 1-infected mice
-
Allen S. J., Mott K. R., Zandian M., Ghiasi H., Immunization with different viral antigens alters the pattern of T cell exhaustion and latency in herpes simplex virus type 1-infected mice Journal of Virology 2010 84 23 12315 12324
-
(2010)
Journal of Virology
, vol.84
, Issue.23
, pp. 12315-12324
-
-
Allen, S.J.1
Mott, K.R.2
Zandian, M.3
Ghiasi, H.4
-
56
-
-
79955444899
-
The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1
-
Allen S. J., Hamrah P., Gate D., Mott K. R., Mantopoulos D., Zheng L., Town T., Jones C., von Andrian U. H., Freeman G. J., Sharpe A. H., BenMohamed L., Ahmed R., Wechsler S. L., Ghiasi H., The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1 Journal of Virology 2011 85 9 4184 4197
-
(2011)
Journal of Virology
, vol.85
, Issue.9
, pp. 4184-4197
-
-
Allen, S.J.1
Hamrah, P.2
Gate, D.3
Mott, K.R.4
Mantopoulos, D.5
Zheng, L.6
Town, T.7
Jones, C.8
Von Andrian, U.H.9
Freeman, G.J.10
Sharpe, A.H.11
Benmohamed, L.12
Ahmed, R.13
Wechsler, S.L.14
Ghiasi, H.15
-
57
-
-
73949138471
-
Early CD4+ T cell help prevents partial CD8+ T cell exhaustion and promotes maintenance of herpes simplex virus 1 latency
-
Frank G. M., Lepisto A. J., Freeman M. L., Sheridan B. S., Cherpes T. L., Hendricks R. L., Early CD4+ T cell help prevents partial CD8+ T cell exhaustion and promotes maintenance of herpes simplex virus 1 latency The Journal of Immunology 2010 184 1 277 286
-
(2010)
The Journal of Immunology
, vol.184
, Issue.1
, pp. 277-286
-
-
Frank, G.M.1
Lepisto, A.J.2
Freeman, M.L.3
Sheridan, B.S.4
Cherpes, T.L.5
Hendricks, R.L.6
-
58
-
-
77954492467
-
Premature terminal exhaustion of friend virus-specific effector CD8+ T cells by rapid induction of multiple inhibitory receptors
-
Takamura S., Tsuji-Kawahara S., Yagita H., Akiba H., Sakamoto M., Chikaishi T., Kato M., Miyazawa M., Premature terminal exhaustion of friend virus-specific effector CD8+ T cells by rapid induction of multiple inhibitory receptors The Journal of Immunology 2010 184 9 4696 4707
-
(2010)
The Journal of Immunology
, vol.184
, Issue.9
, pp. 4696-4707
-
-
Takamura, S.1
Tsuji-Kawahara, S.2
Yagita, H.3
Akiba, H.4
Sakamoto, M.5
Chikaishi, T.6
Kato, M.7
Miyazawa, M.8
-
59
-
-
33644558718
-
Expression of B7-H1 on gastric epithelial cells: Its potential role in regulating T cells during Helicobacter pylori infection
-
Das S., Suarez G., Beswick E. J., Sierra J. C., Graham D. Y., Reyes V. E., Expression of B7-H1 on gastric epithelial cells: its potential role in regulating T cells during Helicobacter pylori infection The Journal of Immunology 2006 176 5 3000 3009
-
(2006)
The Journal of Immunology
, vol.176
, Issue.5
, pp. 3000-3009
-
-
Das, S.1
Suarez, G.2
Beswick, E.J.3
Sierra, J.C.4
Graham, D.Y.5
Reyes, V.E.6
-
60
-
-
33846837101
-
Chronic exposure to Helicobacter pylori impairs dendritic cell function and inhibits Th1 development
-
DOI 10.1128/IAI.00228-06
-
Mitchell P., Germain C., Fiori P. L., Khamri W., Foster G. R., Ghosh S., Lechler R. I., Bamford K. B., Lombardi G., Chronic exposure to Helicobacter pylori impairs dendritic cell function and inhibits Th1 development Infection and Immunity 2007 75 2 810 819 (Pubitemid 46203444)
-
(2007)
Infection and Immunity
, vol.75
, Issue.2
, pp. 810-819
-
-
Mitchell, P.1
Germain, C.2
Fiori, P.L.3
Khamri, W.4
Foster, G.R.5
Ghosh, S.6
Lechler, R.I.7
Bamford, K.B.8
Lombardi, G.9
-
61
-
-
79960133308
-
Expression of CD25high regulatory T cells and PD-1 in gastric infiltrating CD8+ T lymphocytes in patients with Helicobacter pylori infection
-
Wu Y.-Y., Chen J.-H., Kao J.-T., Liu K.-C., Lai C.-H., Wang Y.-M., Hsieh C.-T., Tzen J. T.C., Hsu P.-N., Expression of CD25high regulatory T cells and PD-1 in gastric infiltrating CD8+ T lymphocytes in patients with Helicobacter pylori infection Clinical and Vaccine Immunology 2011 18 7 1198 1201
-
(2011)
Clinical and Vaccine Immunology
, vol.18
, Issue.7
, pp. 1198-1201
-
-
Wu, Y.-Y.1
Chen, J.-H.2
Kao, J.-T.3
Liu, K.-C.4
Lai, C.-H.5
Wang, Y.-M.6
Hsieh, C.-T.7
Tzen, J.T.C.8
Hsu, P.-N.9
-
62
-
-
77955352741
-
Dendritic cells in chronic mycobacterial granulomas restrict local anti-bacterial T cell response in a murine model
-
Schreiber H. A., Hulseberg P. D., Lee J., Prechl J., Barta P., Szlavik N., Harding J. S., Fabry Z., Sandor M., Dendritic cells in chronic mycobacterial granulomas restrict local anti-bacterial T cell response in a murine model PLoS One 2010 5 7
-
(2010)
PLoS One
, vol.5
, Issue.7
-
-
Schreiber, H.A.1
Hulseberg, P.D.2
Lee, J.3
Prechl, J.4
Barta, P.5
Szlavik, N.6
Harding, J.S.7
Fabry, Z.8
Sandor, M.9
-
63
-
-
67249117672
-
B7-H1 blockade increases survival of dysfunctional CD8+ T cells and confers protection against Leishmania donovaniinfections
-
Joshi T., Rodriguez S., Perovic V., Cockburn I. A., Stger S., B7-H1 blockade increases survival of dysfunctional CD8+ T cells and confers protection against Leishmania donovaniinfections PLoS Pathogens 2009 5 5
-
(2009)
PLoS Pathogens
, vol.5
, Issue.5
-
-
Joshi, T.1
Rodriguez, S.2
Perovic, V.3
Cockburn, I.A.4
Stger, S.5
-
64
-
-
79959357729
-
Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade
-
Bhadra R., Gigley J. P., Weiss L. M., Khan I. A., Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade Proceedings of the National Academy of Sciences of the United States of America 2011 108 22 9196 9201
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.22
, pp. 9196-9201
-
-
Bhadra, R.1
Gigley, J.P.2
Weiss, L.M.3
Khan, I.A.4
-
65
-
-
3142750528
-
Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages
-
Smith P., Walsh C. M., Mangan N. E., Fallon R. E., Sayers J. R., McKenzie A. N. J., Fallon P. G., Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages The Journal of Immunology 2004 173 2 1240 1248 (Pubitemid 38924302)
-
(2004)
Journal of Immunology
, vol.173
, Issue.2
, pp. 1240-1248
-
-
Smith, P.1
Walsh, C.M.2
Mangan, N.E.3
Fallon, R.E.4
Sayers, J.R.5
McKenzie, A.N.J.6
Fallon, P.G.7
-
66
-
-
17144409086
-
PD-L2+ dendritic cells and PD-1+ CD4+ T cells in schistosomiasis correlate with morbidity
-
DOI 10.1111/j.1365-3024.2005.00742.x
-
Colley D. G., Sasser L. E., Reed A. M., PD-L2+ dendritic cells and PD-1+ CD4+ T cells in schistosomiasis correlate with morbidity Parasite Immunology 2005 27 1-2 45 53 (Pubitemid 40524992)
-
(2005)
Parasite Immunology
, vol.27
, Issue.1-2
, pp. 45-53
-
-
Colley, D.G.1
Sasser, L.E.2
Reed, A.M.3
-
67
-
-
33947409611
-
Vaccine-induced early control of hepatitis C virus infection in chimpanzees fails to impact on hepatic PD-1 and chronicity
-
DOI 10.1002/hep.21573
-
Rollier C. S., Paranhos-Baccala G., Verschoor E. J., Verstrepen B. E., Drexhage J. A. R., Fagrouch Z., Berland J. L., Komurian-Pradel F., Duverger B., Himoudi N., Staib C., Meyr M., Whelan M., Whelan J. A., Adams V. A., Larrea E., Riezu J. I., Lasarte J. J., Bartosch B., Cosset F. L., Spaan W. J. M., Diepolder H. M., Pape G. R., Sutter G., Inchauspe G., Heeney J. L., Vaccine-induced early control of hepatitis C virus infection in chimpanzees fails to impact on hepatic PD-1 and chronicity Hepatology 2007 45 3 602 613 (Pubitemid 46450611)
-
(2007)
Hepatology
, vol.45
, Issue.3
, pp. 602-613
-
-
Rollier, C.S.1
Paranhos-Baccala, G.2
Verschoor, E.J.3
Verstrepen, B.E.4
Drexhage, J.A.R.5
Fagrouch, Z.6
Berland, J.-L.7
Komurian-Pradel, F.8
Duverger, B.9
Himoudi, N.10
Staib, C.11
Meyr, M.12
Whelan, M.13
Whelan, J.A.14
Adams, V.A.15
Larrea, E.16
Riezu, J.I.17
Lasarte, J.J.18
Bartosch, B.19
Cosset, F.-L.20
Spaan, W.J.M.21
Diepolder, H.M.22
Pape, G.R.23
Sutter, G.24
Inchauspe, G.25
Heeney, J.L.26
more..
-
68
-
-
60549087784
-
PD-1 blockade in rhesus macaques: Impact on chronic infection and prophylactic vaccination
-
Finnefrock A. C., Tang A., Li F., Freed D. C., Feng M., Cox K. S., Sykes K. J., Guare J. P., Miller M. D., Olsen D. B., Hazuda D. J., Shiver J. W., Casimiro D. R., Fu T. M., PD-1 blockade in rhesus macaques: impact on chronic infection and prophylactic vaccination The Journal of Immunology 2009 182 2 980 987
-
(2009)
The Journal of Immunology
, vol.182
, Issue.2
, pp. 980-987
-
-
Finnefrock, A.C.1
Tang, A.2
Li, F.3
Freed, D.C.4
Feng, M.5
Cox, K.S.6
Sykes, K.J.7
Guare, J.P.8
Miller, M.D.9
Olsen, D.B.10
Hazuda, D.J.11
Shiver, J.W.12
Casimiro, D.R.13
Fu, T.M.14
-
69
-
-
79953063507
-
Enhancement of vaccine-induced primary and memory CD8+ t-cell responses by soluble PD-1
-
Song M. -Y., Park S. -H., Nam H. J., Choi D. -H., Sung Y. -C., Enhancement of vaccine-induced primary and memory CD8+ t-cell responses by soluble PD-1 The Journal of Immunotherapy 2011 34 3 297 306
-
(2011)
The Journal of Immunotherapy
, vol.34
, Issue.3
, pp. 297-306
-
-
Song, M.-Y.1
Park, S.-H.2
Nam, H.J.3
Choi, D.-H.4
Sung, Y.-C.5
-
70
-
-
41149112957
-
Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection
-
DOI 10.1084/jem.20071949
-
Ha S. J., Mueller S. N., Wherry E. J., Barber D. L., Aubert R. D., Sharpe A. H., Freeman G. J., Ahmed R., Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection The Journal of Experimental Medicine 2008 205 3 543 555 (Pubitemid 351439302)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.3
, pp. 543-555
-
-
Ha, S.-J.1
Mueller, S.N.2
Wherry, E.J.3
Barber, D.L.4
Aubert, R.D.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
71
-
-
34848852256
-
Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection
-
DOI 10.1073/pnas.0702579104
-
Mueller S. N., Matloubian M., Clemens D. M., Sharpe A. H., Freeman G. J., Gangappa S., Larsen C. P., Ahmed R., Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection Proceedings of the National Academy of Sciences of the United States of America 2007 104 39 15430 15435 (Pubitemid 47502934)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.39
, pp. 15430-15435
-
-
Mueller, S.N.1
Matloubian, M.2
Clemens, D.M.3
Sharpe, A.H.4
Freeman, G.J.5
Gangappa, S.6
Larsen, C.P.7
Ahmed, R.8
-
72
-
-
62249172189
-
Enhancing SIV-specific immunity in vivo by PD-1 blockade
-
Velu V., Titanji K., Zhu B., Husain S., Pladevega A., Lai L., Vanderford T. H., Chennareddi L., Silvestri G., Freeman G. J., Ahmed R., Amara R. R., Enhancing SIV-specific immunity in vivo by PD-1 blockade Nature 2009 458 7235 206 210
-
(2009)
Nature
, vol.458
, Issue.7235
, pp. 206-210
-
-
Velu, V.1
Titanji, K.2
Zhu, B.3
Husain, S.4
Pladevega, A.5
Lai, L.6
Vanderford, T.H.7
Chennareddi, L.8
Silvestri, G.9
Freeman, G.J.10
Ahmed, R.11
Amara, R.R.12
-
73
-
-
49649114804
-
Phase i safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
-
Berger R., Rotem-Yehudar R., Slama G., Landes S., Kneller A., Leiba M., Koren-Michowitz M., Shimoni A., Nagler A., Phase i safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies Clinical Cancer Research 2008 14 10 3044 3051
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.10
, pp. 3044-3051
-
-
Berger, R.1
Rotem-Yehudar, R.2
Slama, G.3
Landes, S.4
Kneller, A.5
Leiba, M.6
Koren-Michowitz, M.7
Shimoni, A.8
Nagler, A.9
-
74
-
-
65649139622
-
PD-L1 negatively regulates CD4+ CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV
-
Franceschini D., Paroli M., Francavilla V., Videtta M., Morrone S., Labbadia G., Cerino A., Mondelli M. U., Barnaba V., PD-L1 negatively regulates CD4+ CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV The Journal of Clinical Investigation 2009 119 3 551 564
-
(2009)
The Journal of Clinical Investigation
, vol.119
, Issue.3
, pp. 551-564
-
-
Franceschini, D.1
Paroli, M.2
Francavilla, V.3
Videtta, M.4
Morrone, S.5
Labbadia, G.6
Cerino, A.7
Mondelli, M.U.8
Barnaba, V.9
-
75
-
-
58149484842
-
IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection
-
Brooks D. G., Ha S. J., Elsaesser H., Sharpe A. H., Freeman G. J., Oldstone M. B. A., IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection Proceedings of the National Academy of Sciences of the United States of America 2008 105 51 20428 20433
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.51
, pp. 20428-20433
-
-
Brooks, D.G.1
Ha, S.J.2
Elsaesser, H.3
Sharpe, A.H.4
Freeman, G.J.5
Oldstone, M.B.A.6
-
76
-
-
57849168934
-
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
-
Blackburn S. D., Shin H., Haining W. N., Zou T., Workman C. J., Polley A., Betts M. R., Freeman G. J., Vignali D. A. A., Wherry E. J., Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection Nature Immunology 2009 10 1 29 37
-
(2009)
Nature Immunology
, vol.10
, Issue.1
, pp. 29-37
-
-
Blackburn, S.D.1
Shin, H.2
Haining, W.N.3
Zou, T.4
Workman, C.J.5
Polley, A.6
Betts, M.R.7
Freeman, G.J.8
Vignali, D.A.A.9
Wherry, E.J.10
-
77
-
-
78049434917
-
Acute depletion of activated memory B cells involves the PD-1 pathway in rapidly progressing SIV-infected macaques
-
Titanji K., Velu V., Chennareddi L., Vijay-Kumar M., Gewirtz A. T., Freeman G. J., Amara R. R., Acute depletion of activated memory B cells involves the PD-1 pathway in rapidly progressing SIV-infected macaques The Journal of Clinical Investigation 2010 120 11 3878 3890
-
(2010)
The Journal of Clinical Investigation
, vol.120
, Issue.11
, pp. 3878-3890
-
-
Titanji, K.1
Velu, V.2
Chennareddi, L.3
Vijay-Kumar, M.4
Gewirtz, A.T.5
Freeman, G.J.6
Amara, R.R.7
-
78
-
-
77955636377
-
Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis
-
Lzr-Molnr E., Chen B., Sweeney K. A., Wang E. J., Liu W., Lin J., Porcelli S. A., Almo S. C., Nathenson S. G., Jacobs W. R., Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis Proceedings of the National Academy of Sciences of the United States of America 2010 107 30 13402 13407
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.30
, pp. 13402-13407
-
-
Lzr-Molnr, E.1
Chen, B.2
Sweeney, K.A.3
Wang, E.J.4
Liu, W.5
Lin, J.6
Porcelli, S.A.7
Almo, S.C.8
Nathenson, S.G.9
Jacobs, W.R.10
-
79
-
-
79251578015
-
CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition
-
Barber D. L., Mayer-Barber K. D., Feng C. G., Sharpe A. H., Sher A., CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition The Journal of Immunology 2011 186 3 1598 1607
-
(2011)
The Journal of Immunology
, vol.186
, Issue.3
, pp. 1598-1607
-
-
Barber, D.L.1
Mayer-Barber, K.D.2
Feng, C.G.3
Sharpe, A.H.4
Sher, A.5
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