-
1
-
-
79551667504
-
In-silico ADME models: A general assessment of their utility in drug discovery applications
-
Gleeson, M. P.; Hersey, A.; Hannongbua, S. In-silico ADME models: A general assessment of their utility in drug discovery applications. Curr. Top. Med. Chem., 2011, 11 (4), 358-381.
-
(2011)
Curr. Top. Med. Chem
, vol.11
, Issue.4
, pp. 358-381
-
-
Gleeson, M.P.1
Hersey, A.2
Hannongbua, S.3
-
2
-
-
77953530689
-
Contributions of computational chemistry and biophysical techniques to fragmentbased drug discovery
-
Gozalbes, R.; Carbajo, R. J.; Pineda-Lucena, A. Contributions of computational chemistry and biophysical techniques to fragmentbased drug discovery. Curr. Med. Chem., 2010, 17 (17), 1769-1794
-
(2010)
Curr. Med. Chem
, vol.17
, Issue.17
, pp. 1769-1794
-
-
Gozalbes, R.1
Carbajo, R.J.2
Pineda-Lucena, A.3
-
3
-
-
80052864956
-
In silico SNP analysis and bioinformatics tools: A review of the state of the art to aid drug discovery
-
Mah, J. T.; Low, E. S.; Lee, E. In silico SNP analysis and bioinformatics tools: A review of the state of the art to aid drug discovery. Drug Discov. Today, 2011, 16 (17-18), 800-809.
-
(2011)
Drug Discov. Today
, vol.16
, Issue.17-18
, pp. 800-809
-
-
Mah, J.T.1
Low, E.S.2
Lee, E.3
-
4
-
-
71249128422
-
Structure-based virtual ligand screening: Recent success stories
-
Villoutreix, B. O.; Eudes, R.; Miteva, M. A. Structure-based virtual ligand screening: recent success stories. Comb. Chem. High Throughput Screening, 2009, 12 (10), 1000-1016.
-
(2009)
Comb. Chem. High Throughput Screening
, vol.12
, Issue.10
, pp. 1000-1016
-
-
Villoutreix, B.O.1
Eudes, R.2
Miteva, M.A.3
-
5
-
-
77957960396
-
Ligand-based computer-aided discovery of tyrosinase inhibitors. Applications of the TOMOCOMDCARDD method to the elucidation of new compounds
-
Marrero-Ponce, Y.; Casanola-Martin, G. M.; Khan, M. T.; Torrens, F.; Rescigno, A.; Abad, C. Ligand-based computer-aided discovery of tyrosinase inhibitors. Applications of the TOMOCOMDCARDD method to the elucidation of new compounds. Curr. Pharm. Des., 2010, 16 (24), 2601-2624.
-
(2010)
Curr. Pharm. Des
, vol.16
, Issue.24
, pp. 2601-2624
-
-
Marrero-Ponce, Y.1
Casanola-Martin, G.M.2
Khan, M.T.3
Torrens, F.4
Rescigno, A.5
Abad, C.6
-
6
-
-
79956188485
-
Computer-aided drug discovery and development
-
Zhang, S. Computer-aided drug discovery and development. Methods Mol. Biol., 2011, 716, 23-38.
-
(2011)
Methods Mol. Biol
, vol.716
, pp. 23-38
-
-
Zhang, S.1
-
7
-
-
33947258002
-
Ligand-based drug design methodologies in drug discovery process: An overview
-
Bacilieri, M.; Moro, S. Ligand-based drug design methodologies in drug discovery process: An overview. Curr. Drug Disc. Technol., 2006, 3 (3), 155-165.
-
(2006)
Curr. Drug Disc. Technol
, vol.3
, Issue.3
, pp. 155-165
-
-
Bacilieri, M.1
Moro, S.2
-
8
-
-
80052858265
-
Structure-based drug design to augment hit discovery
-
Kalyaanamoorthy, S.; Chen, Y. P. Structure-based drug design to augment hit discovery. Drug Discov. Today, 2011, 16 (17-18), 831-839.
-
(2011)
Drug Discov. Today
, vol.16
, Issue.17-18
, pp. 831-839
-
-
Kalyaanamoorthy, S.1
Chen, Y.P.2
-
9
-
-
0034740222
-
Drug design by machine learning: Support vector machines for pharmaceutical data analysis
-
Burbidge, R.; Trotter, M.; Buxton, B.; Holden, S. Drug design by machine learning: support vector machines for pharmaceutical data analysis. Comput. Chem., 2001, 26 (1), 5-14.
-
(2001)
Comput. Chem
, vol.26
, Issue.1
, pp. 5-14
-
-
Burbidge, R.1
Trotter, M.2
Buxton, B.3
Holden, S.4
-
10
-
-
13444265939
-
Judging the significance of multiple linear regression models
-
Livingstone, D. J.; Salt, D. W. Judging the significance of multiple linear regression models. J. Med. Chem., 2005, 48 (3), 661-663.
-
(2005)
J. Med. Chem
, vol.48
, Issue.3
, pp. 661-663
-
-
Livingstone, D.J.1
Salt, D.W.2
-
11
-
-
0034548887
-
Protein structure-based de novo design and synthesis of aldose reductase inhibitors
-
Iwata, Y.; Naito, S.; Itai, A.; Miyamoto, S. Protein structure-based de novo design and synthesis of aldose reductase inhibitors. Drug Des. Discov., 2001, 17 (4), 349-359.
-
(2001)
Drug Des. Discov
, vol.17
, Issue.4
, pp. 349-359
-
-
Iwata, Y.1
Naito, S.2
Itai, A.3
Miyamoto, S.4
-
12
-
-
0035800608
-
Discovery of a new inhibitor lead of adenovirus proteinase: Steps toward selective, irreversible inhibitors of cysteine proteinases
-
Pang, Y. P.; Xu, K.; Kollmeyer, T. M.; Perola, E.; McGrath, W. J.; Green, D. T.; Mangel, W. F. Discovery of a new inhibitor lead of adenovirus proteinase: steps toward selective, irreversible inhibitors of cysteine proteinases. FEBS Lett., 2001, 502 (3), 93-97.
-
(2001)
FEBS Lett
, vol.502
, Issue.3
, pp. 93-97
-
-
Pang, Y.P.1
Xu, K.2
Kollmeyer, T.M.3
Perola, E.4
McGrath, W.J.5
Green, D.T.6
Mangel, W.F.7
-
13
-
-
34247267634
-
Gamma-Aminobutyric Acid (GABA) receptor mediates suanzaorentang, a traditional Chinese herb remedy,-induced sleep alteration
-
Yi, P. L.; Tsai, C. H.; Chen, Y. C.; Chang, F. C. Gamma-Aminobutyric Acid (GABA) receptor mediates suanzaorentang, a traditional Chinese herb remedy,-induced sleep alteration. J. Biomed. Sci., 2007, 14 (2), 285-297.
-
(2007)
J. Biomed. Sci
, vol.14
, Issue.2
, pp. 285-297
-
-
Yi, P.L.1
Tsai, C.H.2
Chen, Y.C.3
Chang, F.C.4
-
14
-
-
13944263886
-
Comparison of automated docking programs as virtual screening tools
-
Cummings, M. D.; DesJarlais, R. L.; Gibbs, A. C.; Mohan, V.; Jaeger, E. P. Comparison of automated docking programs as virtual screening tools. J. Med. Chem., 2005, 48 (4), 962-976.
-
(2005)
J. Med. Chem
, vol.48
, Issue.4
, pp. 962-976
-
-
Cummings, M.D.1
Desjarlais, R.L.2
Gibbs, A.C.3
Mohan, V.4
Jaeger, E.P.5
-
16
-
-
1442293369
-
Current state and perspectives of 3D-QSAR
-
Akamatsu, M. Current state and perspectives of 3D-QSAR. Curr. Top. Med. Chem., 2002, 2 (12), 1381-1394.
-
(2002)
Curr. Top. Med. Chem
, vol.2
, Issue.12
, pp. 1381-1394
-
-
Akamatsu, M.1
-
17
-
-
33750898990
-
Molecular mechanics methods for predicting protein-ligand binding
-
Huang, N.; Kalyanaraman, C.; Bernacki, K.; Jacobson, M. P. Molecular mechanics methods for predicting protein-ligand binding. PCCP, 2006, 8 (44), 5166-5177.
-
(2006)
PCCP
, vol.8
, Issue.44
, pp. 5166-5177
-
-
Huang, N.1
Kalyanaraman, C.2
Bernacki, K.3
Jacobson, M.P.4
-
18
-
-
1542424403
-
Molecular dynamics simulations: A tool for drug design
-
Rognan, D. Molecular dynamics simulations: A tool for drug design. Perspect. Drug Discovery Des., 1998, 9-11 (0), 181-209.
-
(1998)
Perspect. Drug Discovery Des
, vol.9-11
, pp. 181-209
-
-
Rognan, D.1
-
19
-
-
0001383234
-
-
Güner, O. F., Ed. International University Line, La Jolla, CA
-
Li, H.; Sutter, J.; Hoffman, R., In Pharmacophore Perception, Development, and Use in Drug Design, Güner, O. F., Ed. International University Line, La Jolla, CA: 2000; pp 171-189.
-
(2000)
Pharmacophore Perception, Development, and Use In Drug Design
, pp. 171-189
-
-
Li, H.1
Sutter, J.2
Hoffman, R.3
-
20
-
-
79952209193
-
Screening from the World's largest TCM database against H1N1 virus
-
Chang, T. T.; Sun, M. F.; Chen, H. Y.; Tsai, F. J.; Fisher, M.; Lin, J. G.; Chen, C. Y. C. Screening from the World's largest TCM database against H1N1 virus. J. Biomol. Struct. Dyn., 2011, 28 (5), 773-786.
-
(2011)
J. Biomol. Struct. Dyn
, vol.28
, Issue.5
, pp. 773-786
-
-
Chang, T.T.1
Sun, M.F.2
Chen, H.Y.3
Tsai, F.J.4
Fisher, M.5
Lin, J.G.6
Chen, C.Y.C.7
-
21
-
-
80052230598
-
Search for novel remedies to augment radiation resistance of inhabitants of Fukushima and Chernobyl disasters
-
Sun, M. F.; Chen, H. Y.; Tsai, F. J.; Liu, S. H.; Chen, C. Y.; Chen, C. Y. C. Search for novel remedies to augment radiation resistance of inhabitants of Fukushima and Chernobyl disasters. J. Biomol. Struct. Dyn., 2011, 29 (2), 325-338.
-
(2011)
J. Biomol. Struct. Dyn
, vol.29
, Issue.2
, pp. 325-338
-
-
Sun, M.F.1
Chen, H.Y.2
Tsai, F.J.3
Liu, S.H.4
Chen, C.Y.5
Chen, C.Y.C.6
-
22
-
-
78650945927
-
Potent inhibitor design against H1N1 swine influenza: Structure-based and molecular dynamics analysis for M2 inhibitors from traditional Chinese medicine database
-
Lin, C. H.; Chang, T. T.; Sun, M. F.; Chen, H. Y.; Tsai, F. J.; Chang, K. L.; Fisher, M.; Chen, C. Y. C. Potent inhibitor design against H1N1 swine influenza: Structure-based and molecular dynamics analysis for M2 inhibitors from traditional Chinese medicine database. J. Biomol. Struct. Dyn., 2011, 28 (4), 471-482.
-
(2011)
J. Biomol. Struct. Dyn
, vol.28
, Issue.4
, pp. 471-482
-
-
Lin, C.H.1
Chang, T.T.2
Sun, M.F.3
Chen, H.Y.4
Tsai, F.J.5
Chang, K.L.6
Fisher, M.7
Chen, C.Y.C.8
-
23
-
-
78649900290
-
Key features for designing phosphodiesterase-5 inhibitors
-
Sun, M. F.; Chang, T. T.; Huang, H. J.; Lee, K. J.; Yu, H. W.; Chen, H. Y.; Tsai, F. J.; Chen, C. Y. C. Key features for designing phosphodiesterase-5 inhibitors. J. Biomol. Struct. Dyn., 2010, 28 (3), 309-321.
-
(2010)
J. Biomol. Struct. Dyn
, vol.28
, Issue.3
, pp. 309-321
-
-
Sun, M.F.1
Chang, T.T.2
Huang, H.J.3
Lee, K.J.4
Yu, H.W.5
Chen, H.Y.6
Tsai, F.J.7
Chen, C.Y.C.8
-
24
-
-
79958717554
-
Blocking the DNA repair system by traditional Chinese medicine
-
Sun, M. F.; Chang, T. T.; Chang, K. W.; Huang, H. J.; Chen, H. Y.; Tsai, F. J.; Lin, J. G.; Chen, C. Y. C. Blocking the DNA repair system by traditional Chinese medicine? J. Biomol. Struct. Dyn., 2011, 28 (6), 895-906.
-
(2011)
J. Biomol. Struct. Dyn
, vol.28
, Issue.6
, pp. 895-906
-
-
Sun, M.F.1
Chang, T.T.2
Chang, K.W.3
Huang, H.J.4
Chen, H.Y.5
Tsai, F.J.6
Lin, J.G.7
Chen, C.Y.C.8
-
25
-
-
84855282742
-
Two birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicine
-
Chang, S. S.; Huang, H. J.; Chen, C. Y. C. Two birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicine. PLoS Comp. Biol., 2011, 7 (12), e1002315.
-
(2011)
PLoS Comp. Biol
, vol.7
, Issue.12
-
-
Chang, S.S.1
Huang, H.J.2
Chen, C.Y.C.3
-
26
-
-
80055077153
-
Identification of potent EGFR inhibitors from TCM Database@Taiwan
-
Yang, S. C.; Chang, S. S.; Chen, H. Y.; Chen, C. Y. C. Identification of potent EGFR inhibitors from TCM Database@Taiwan. PLoS Comp. Biol., 2011, 7 (10), e1002189.
-
(2011)
PLoS Comp. Biol
, vol.7
, Issue.10
-
-
Yang, S.C.1
Chang, S.S.2
Chen, H.Y.3
Chen, C.Y.C.4
-
27
-
-
80052619174
-
Investigation into potent in_ammation inhibitors from traditional Chinese medicine
-
Chen, K. C.; Sun, M. F.; Yang, S. C.; Chang, S. S.; Chen, H. Y.; Tsai, F. J.; Chen, C. Y. C. Investigation into potent in_ammation inhibitors from traditional Chinese medicine. Chem. Biol. Drug Des., 2011, 78 (4), 679-688.
-
(2011)
Chem. Biol. Drug Des
, vol.78
, Issue.4
, pp. 679-688
-
-
Chen, K.C.1
Sun, M.F.2
Yang, S.C.3
Chang, S.S.4
Chen, H.Y.5
Tsai, F.J.6
Chen, C.Y.C.7
-
28
-
-
77957873171
-
Cantharidin induces apoptosis in human bladder cancer TSGH 8301 cells through mitochondriadependent signal pathways
-
Kuo, J. H.; Chu, Y. L.; Yang, J. S.; Lin, J. P.; Lai, K. C.; Kuo, H. M.; Hsia, T. C.; Chung, J. G. Cantharidin induces apoptosis in human bladder cancer TSGH 8301 cells through mitochondriadependent signal pathways. Int. J. Oncol., 2010, 37 (5), 1243-1250.
-
(2010)
Int. J. Oncol
, vol.37
, Issue.5
, pp. 1243-1250
-
-
Kuo, J.H.1
Chu, Y.L.2
Yang, J.S.3
Lin, J.P.4
Lai, K.C.5
Kuo, H.M.6
Hsia, T.C.7
Chung, J.G.8
-
29
-
-
77649181622
-
A novel compound, NP-184, inhibits the vascular endothelial growth factor induced angiogenesis
-
Lin, K. T.; Lien, J. C.; Chung, C. H.; Kuo, S. C.; Huang, T. F. A novel compound, NP-184, inhibits the vascular endothelial growth factor induced angiogenesis. Eur. J. Pharmacol., 2010, 630 (1-3), 53-60.
-
(2010)
Eur. J. Pharmacol
, vol.630
, Issue.1-3
, pp. 53-60
-
-
Lin, K.T.1
Lien, J.C.2
Chung, C.H.3
Kuo, S.C.4
Huang, T.F.5
-
30
-
-
78651359258
-
Triptolide induces apoptosis in human adrenal cancer NCI-H295 cells through a mitochondrial-dependent pathway
-
Wu, P. P.; Liu, K. C.; Huang, W. W.; Ma, C. Y.; Lin, H.; Yang, J. S.; Chung, J. G. Triptolide induces apoptosis in human adrenal cancer NCI-H295 cells through a mitochondrial-dependent pathway. Oncol. Rep., 2011, 25 (2), 551-557.
-
(2011)
Oncol. Rep
, vol.25
, Issue.2
, pp. 551-557
-
-
Wu, P.P.1
Liu, K.C.2
Huang, W.W.3
Ma, C.Y.4
Lin, H.5
Yang, J.S.6
Chung, J.G.7
-
31
-
-
12544250381
-
Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling
-
Le, X. F.; Lammayot, A.; Gold, D.; Lu, Y.; Mao, W.; Chang, T.; Patel, A.; Mills, G. B.; Bast, R. C., Jr. Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling. J. Biol. Chem., 2005, 280 (3), 2092-2104.
-
(2005)
J. Biol. Chem
, vol.280
, Issue.3
, pp. 2092-2104
-
-
Le, X.F.1
Lammayot, A.2
Gold, D.3
Lu, Y.4
Mao, W.5
Chang, T.6
Patel, A.7
Mills, G.B.8
Bast Jr., R.C.9
-
32
-
-
0034766736
-
Biology of HER2 and its importance in breast cancer
-
Yarden, Y. Biology of HER2 and its importance in breast cancer. Oncology, 2001, 61 Suppl 2, 1-13.
-
Oncology, 2001, 61 Suppl
, vol.2
, pp. 1-13
-
-
Yarden, Y.1
-
33
-
-
34249947556
-
HER2-positive breast cancer: Current and future treatment strategies
-
Engel, R. H.; Kaklamani, V. G. HER2-positive breast cancer: current and future treatment strategies. Drugs, 2007, 67 (9), 1329-1341.
-
(2007)
Drugs
, vol.67
, Issue.9
, pp. 1329-1341
-
-
Engel, R.H.1
Kaklamani, V.G.2
-
34
-
-
0023019645
-
Expression of epidermal growth factor receptors on normal human gastric epithelia and gastric carcinomas
-
Sakai, K.; Mori, S.; Kawamoto, T.; Taniguchi, S.; Kobori, O.; Morioka, Y.; Kuroki, T.; Kano, K. Expression of epidermal growth factor receptors on normal human gastric epithelia and gastric carcinomas. J. Natl. Cancer Inst., 1986, 77 (5), 1047-1052.
-
(1986)
J. Natl. Cancer Inst
, vol.77
, Issue.5
, pp. 1047-1052
-
-
Sakai, K.1
Mori, S.2
Kawamoto, T.3
Taniguchi, S.4
Kobori, O.5
Morioka, Y.6
Kuroki, T.7
Kano, K.8
-
35
-
-
0034614093
-
HER2 in prostate cancer--a viable target or innocent bystander
-
Scher, H. I. HER2 in prostate cancer--a viable target or innocent bystander? J. Natl. Cancer Inst., 2000, 92 (23), 1866-1868.
-
(2000)
J. Natl. Cancer Inst
, vol.92
, Issue.23
, pp. 1866-1868
-
-
Scher, H.I.1
-
36
-
-
0034614108
-
Her-2-neu expression and progression toward androgen independence in human prostate cancer
-
Signoretti, S.; Montironi, R.; Manola, J.; Altimari, A.; Tam, C.; Bubley, G.; Balk, S.; Thomas, G.; Kaplan, I.; Hlatky, L.; Hahnfeldt, P.; Kantoff, P.; Loda, M. Her-2-neu expression and progression toward androgen independence in human prostate cancer. J. Natl. Cancer Inst., 2000, 92 (23), 1918-1925.
-
(2000)
J. Natl. Cancer Inst
, vol.92
, Issue.23
, pp. 1918-1925
-
-
Signoretti, S.1
Montironi, R.2
Manola, J.3
Altimari, A.4
Tam, C.5
Bubley, G.6
Balk, S.7
Thomas, G.8
Kaplan, I.9
Hlatky, L.10
Hahnfeldt, P.11
Kantoff, P.12
Loda, M.13
-
37
-
-
79952162826
-
HER2-amplified breast cancer: Mechanisms of trastuzumab resistance and novel targeted therapies
-
Gajria, D.; Chandarlapaty, S. HER2-amplified breast cancer: mechanisms of trastuzumab resistance and novel targeted therapies. Expert Rev. Anticancer Ther, 2011, 11 (2), 263-275.
-
(2011)
Expert Rev. Anticancer Ther
, vol.11
, Issue.2
, pp. 263-275
-
-
Gajria, D.1
Chandarlapaty, S.2
-
38
-
-
77955298667
-
Lapatinib side-effect management
-
Frankel, C.; Palmieri, F. M. Lapatinib side-effect management. Clin. J. Oncol. Nurs., 2010, 14 (2), 223-233.
-
(2010)
Clin. J. Oncol. Nurs
, vol.14
, Issue.2
, pp. 223-233
-
-
Frankel, C.1
Palmieri, F.M.2
-
39
-
-
79251561193
-
TCM Database@Taiwan: The World's largest traditional Chinese medicine database for drug screening in silico
-
Chen, C. Y. C. TCM Database@Taiwan: The World's largest traditional Chinese medicine database for drug screening in silico. PLoS ONE, 2011, 6 (1), e15939.
-
(2011)
PLoS ONE
, vol.6
, Issue.1
-
-
Chen, C.Y.C.1
-
40
-
-
77949353758
-
Discovery of 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanam ide (CUDc-101) as a potent multi-acting HDAC, EGFR, and HER2 inhibitor for the treatment of cancer
-
Cai, X.; Zhai, H. X.; Wang, J.; Forrester, J.; Qu, H.; Yin, L.; Lai, C. J.; Bao, R.; Qian, C. Discovery of 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanam ide (CUDc-101) as a potent multi-acting HDAC, EGFR, and HER2 inhibitor for the treatment of cancer. J. Med. Chem., 2010, 53 (5), 2000-2009.
-
(2010)
J. Med. Chem
, vol.53
, Issue.5
, pp. 2000-2009
-
-
Cai, X.1
Zhai, H.X.2
Wang, J.3
Forrester, J.4
Qu, H.5
Yin, L.6
Lai, C.J.7
Bao, R.8
Qian, C.9
-
41
-
-
33845956331
-
Synthesis and biological evaluation of 4-aryl-5-cyano-2H-1,2,3-triazoles as inhibitor of HER2 tyrosine kinase
-
Cheng, Z. Y.; Li, W. J.; He, F.; Zhou, J. M.; Zhu, X. F. Synthesis and biological evaluation of 4-aryl-5-cyano-2H-1,2,3-triazoles as inhibitor of HER2 tyrosine kinase. Biorg. Med. Chem., 2007, 15 (3), 1533-1538.
-
(2007)
Biorg. Med. Chem
, vol.15
, Issue.3
, pp. 1533-1538
-
-
Cheng, Z.Y.1
Li, W.J.2
He, F.3
Zhou, J.M.4
Zhu, X.F.5
-
42
-
-
0036836964
-
Development of a purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells and induce the degradation of Her2 tyrosine kinase
-
Chiosis, G.; Lucas, B.; Shtil, A.; Huezo, H.; Rosen, N. Development of a purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells and induce the degradation of Her2 tyrosine kinase. Bioorg. Med. Chem., 2002, 10 (11), 3555-3564.
-
(2002)
Bioorg. Med. Chem
, vol.10
, Issue.11
, pp. 3555-3564
-
-
Chiosis, G.1
Lucas, B.2
Shtil, A.3
Huezo, H.4
Rosen, N.5
-
43
-
-
25144513049
-
New dual inhibitors of EGFR and HER2 protein tyrosine kinases
-
Fink, B. E.; Vite, G. D.; Mastalerz, H.; Kadow, J. F.; Kim, S. H.; Leavitt, K. J.; Du, K.; Crews, D.; Mitt, T.; Wong, T. W.; Hunt, J. T.; Vyas, D. M.; Tokarski, J. S. New dual inhibitors of EGFR and HER2 protein tyrosine kinases. Bioorg. Med. Chem. Lett., 2005, 15 (21), 4774-4779.
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, Issue.21
, pp. 4774-4779
-
-
Fink, B.E.1
Vite, G.D.2
Mastalerz, H.3
Kadow, J.F.4
Kim, S.H.5
Leavitt, K.J.6
Du, K.7
Crews, D.8
Mitt, T.9
Wong, T.W.10
Hunt, J.T.11
Vyas, D.M.12
Tokarski, J.S.13
-
44
-
-
58749114540
-
Synthesis and evaluation of Hsp90 inhibitors that contain the 1,4-naphthoquinone scaffold
-
Hadden, M. K.; Hill, S. A.; Davenport, J.; Matts, R. L.; Blagg, B. S. Synthesis and evaluation of Hsp90 inhibitors that contain the 1,4-naphthoquinone scaffold. Biorg. Med. Chem., 2009, 17 (2), 634-640.
-
(2009)
Biorg. Med. Chem
, vol.17
, Issue.2
, pp. 634-640
-
-
Hadden, M.K.1
Hill, S.A.2
Davenport, J.3
Matts, R.L.4
Blagg, B.S.5
-
45
-
-
67650741952
-
Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents
-
Huang, K. H.; Veal, J. M.; Fadden, R. P.; Rice, J. W.; Eaves, J.; Strachan, J. P.; Barabasz, A. F.; Foley, B. E.; Barta, T. E.; Ma, W.; Silinski, M. A.; Hu, M.; Partridge, J. M.; Scott, A.; DuBois, L. G.; Freed, T.; Steed, P. M.; Ommen, A. J.; Smith, E. D.; Hughes, P. F.; Woodward, A. R.; Hanson, G. J.; McCall, W. S.; Markworth, C. J.; Hinkley, L.; Jenks, M.; Geng, L.; Lewis, M.; Otto, J.; Pronk, B.; Verleysen, K.; Hall, S. E. Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. J. Med. Chem., 2009, 52 (14), 4288-4305.
-
(2009)
J. Med. Chem
, vol.52
, Issue.14
, pp. 4288-4305
-
-
Huang, K.H.1
Veal, J.M.2
Fadden, R.P.3
Rice, J.W.4
Eaves, J.5
Strachan, J.P.6
Barabasz, A.F.7
Foley, B.E.8
Barta, T.E.9
Ma, W.10
Silinski, M.A.11
Hu, M.12
Partridge, J.M.13
Scott, A.14
Dubois, L.G.15
Freed, T.16
Steed, P.M.17
Ommen, A.J.18
Smith, E.D.19
Hughes, P.F.20
Woodward, A.R.21
Hanson, G.J.22
McCall, W.S.23
Markworth, C.J.24
Hinkley, L.25
Jenks, M.26
Geng, L.27
Lewis, M.28
Otto, J.29
Pronk, B.30
Verleysen, K.31
Hall, S.E.32
more..
-
46
-
-
0003008238
-
Synthesis and evaluation of geldanamycinestradiol hybrids Bioorg
-
Kuduk, S. D.; Zheng, F. F.; Sepp-Lorenzino, L.; Rosen, N.; Danishefsky, S. J. Synthesis and evaluation of geldanamycinestradiol hybrids Bioorg. Med. Chem. Lett., 1999, 9 (9), 1233-1238
-
(1999)
Med. Chem. Lett
, vol.9
, Issue.9
, pp. 1233-1238
-
-
Kuduk, S.D.1
Zheng, F.F.2
Sepp-Lorenzino, L.3
Rosen, N.4
Danishefsky, S.J.5
-
47
-
-
72049109416
-
Synthesis and structure-activity relationships of N-benzyl-N-(X-2-hydroxybenzyl)-N '-phenylureas and thioureas as antitumor agents
-
Li, H. Q.; Yan, T.; Yang, Y.; Shi, L.; Zhou, C. F.; Zhu, H. L. Synthesis and structure-activity relationships of N-benzyl-N-(X-2-hydroxybenzyl)-N '-phenylureas and thioureas as antitumor agents. Biorg. Med. Chem., 2010, 18 (1), 305-313.
-
(2010)
Biorg. Med. Chem
, vol.18
, Issue.1
, pp. 305-313
-
-
Li, H.Q.1
Yan, T.2
Yang, Y.3
Shi, L.4
Zhou, C.F.5
Zhu, H.L.6
-
48
-
-
34248176943
-
The discovery of highly selective erbB2 (Her2) inhibitors for the treatment of cancer
-
Lippa, B.; Kauffman, G. S.; Arcari, J.; Kwan, T.; Chen, J. S.; Hungerford, W.; Bhattacharya, S.; Zhao, X. M.; Williams, C.; Xiao, J.; Pustilnik, L.; Su, C. Y.; Moyer, J. D.; Ma, L.; Campbell, M.; Steyn, S. The discovery of highly selective erbB2 (Her2) inhibitors for the treatment of cancer. Bioorg. Med. Chem. Lett., 2007, 17 (11), 3081-3086.
-
(2007)
Bioorg. Med. Chem. Lett
, vol.17
, Issue.11
, pp. 3081-3086
-
-
Lippa, B.1
Kauffman, G.S.2
Arcari, J.3
Kwan, T.4
Chen, J.S.5
Hungerford, W.6
Bhattacharya, S.7
Zhao, X.M.8
Williams, C.9
Xiao, J.10
Pustilnik, L.11
Su, C.Y.12
Moyer, J.D.13
Ma, L.14
Campbell, M.15
Steyn, S.16
-
49
-
-
72049095834
-
Design, synthesis and biological evaluation of thiazolidinone derivatives as potential EGFR and HER-2 kinase inhibitors
-
Lv, P. C.; Zhou, C. F.; Chen, J.; Liu, P. G.; Wang, K. R.; Mao, W. J.; Li, H. Q.; Yang, Y.; Xiong, J.; Zhu, H. L. Design, synthesis and biological evaluation of thiazolidinone derivatives as potential EGFR and HER-2 kinase inhibitors. Biorg. Med. Chem., 2010, 18 (1), 314-319.
-
(2010)
Biorg. Med. Chem
, vol.18
, Issue.1
, pp. 314-319
-
-
Lv, P.C.1
Zhou, C.F.2
Chen, J.3
Liu, P.G.4
Wang, K.R.5
Mao, W.J.6
Li, H.Q.7
Yang, Y.8
Xiong, J.9
Zhu, H.L.10
-
50
-
-
0030762373
-
Inhibition of the Her2 tyrosine kinase and characterization of a hydrophobic site near the nucleotide binding domain
-
A. Maddry, J. A. Kussner, C.W. Truss, J. W. Niwas, S. White, E. L. Kwong, C. D. Inhibition of the Her2 tyrosine kinase and characterization of a hydrophobic site near the nucleotide binding domain. Bioorg. Med. Chem. Lett., 1997, 7 (16), 2109-2114.
-
(1997)
Bioorg. Med. Chem. Lett
, vol.7
, Issue.16
, pp. 2109-2114
-
-
Maddry, A.1
Kussner, J.A.2
Truss, C.W.3
Niwas, J.W.4
White, S.5
Kwong, C.D.6
-
51
-
-
0028467707
-
Application of genetic function approximation to quantitative structure-activity relationships and quantitative structure-property relationships
-
Rogers, D.; Hopfinger, A. J. Application of genetic function approximation to quantitative structure-activity relationships and quantitative structure-property relationships J. Chem. Inf. Comput. Sci., 1994, 34 (4), 854-866
-
(1994)
J. Chem. Inf. Comput. Sci
, vol.34
, Issue.4
, pp. 854-866
-
-
Rogers, D.1
Hopfinger, A.J.2
-
52
-
-
0037136012
-
Rational design of 4,5-disubstituted-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-ones as a novel class of inhibitors of epidermal growth factor receptor (EGF-R) and Her2(p185(erbB)) tyrosine kinases
-
Sun, L.; Cui, J.; Liang, C.; Zhou, Y.; Nematalla, A.; Wang, X.; Chen, H.; Tang, C.; Wei, J. Rational design of 4,5-disubstituted-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-ones as a novel class of inhibitors of epidermal growth factor receptor (EGF-R) and Her2(p185(erbB)) tyrosine kinases. Bioorg. Med. Chem. Lett., 2002, 12 (16), 2153-2157.
-
(2002)
Bioorg. Med. Chem. Lett
, vol.12
, Issue.16
, pp. 2153-2157
-
-
Sun, L.1
Cui, J.2
Liang, C.3
Zhou, Y.4
Nematalla, A.5
Wang, X.6
Chen, H.7
Tang, C.8
Wei, J.9
-
53
-
-
48649084335
-
4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors
-
Xu, G.; Abad, M. C.; Connolly, P. J.; Neeper, M. P.; Struble, G. T.; Springer, B. A.; Emanuel, S. L.; Pandey, N.; Gruninger, R. H.; Adams, M.; Moreno-Mazza, S.; Fuentes-Pesquera, A. R.; Middleton, S. A. 4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors. Bioorg. Med. Chem. Lett., 2008, 18 (16), 4615-4619.
-
(2008)
Bioorg. Med. Chem. Lett
, vol.18
, Issue.16
, pp. 4615-4619
-
-
Xu, G.1
Abad, M.C.2
Connolly, P.J.3
Neeper, M.P.4
Struble, G.T.5
Springer, B.A.6
Emanuel, S.L.7
Pandey, N.8
Gruninger, R.H.9
Adams, M.10
Moreno-Mazza, S.11
Fuentes-Pesquera, A.R.12
Middleton, S.A.13
-
54
-
-
44849136560
-
Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases
-
Xu, G.; Searle, L. L.; Hughes, T. V.; Beck, A. K.; Connolly, P. J.; Abad, M. C.; Neeper, M. P.; Struble, G. T.; Springer, B. A.; Emanuel, S. L.; Gruninger, R. H.; Pandey, N.; Adams, M.; Moreno-Mazza, S.; Fuentes-Pesquera, A. R.; Middleton, S. A.; Greenberger, L. M. Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases. Bioorg. Med. Chem. Lett., 2008, 18 (12), 3495-3499.
-
(2008)
Bioorg. Med. Chem. Lett
, vol.18
, Issue.12
, pp. 3495-3499
-
-
Xu, G.1
Searle, L.L.2
Hughes, T.V.3
Beck, A.K.4
Connolly, P.J.5
Abad, M.C.6
Neeper, M.P.7
Struble, G.T.8
Springer, B.A.9
Emanuel, S.L.10
Gruninger, R.H.11
Pandey, N.12
Adams, M.13
Moreno-Mazza, S.14
Fuentes-Pesquera, A.R.15
Middleton, S.A.16
Greenberger, L.M.17
-
55
-
-
0033954256
-
The Protein Data Bank
-
Berman, H. M.; Westbrook, J.; Feng, Z.; Gilliland, G.; Bhat, T. N.; Weissig, H.; Shindyalov, I. N.; Bourne, P. E. The Protein Data Bank. Nucleic Acids Res., 2000, 28 (1), 235-242.
-
(2000)
Nucleic Acids Res
, vol.28
, Issue.1
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
Weissig, H.6
Shindyalov, I.N.7
Bourne, P.E.8
-
56
-
-
0035812694
-
Protein structure prediction and structural genomics
-
Baker, D.; Sali, A. Protein structure prediction and structural genomics. Science, 2001, 294 (5540), 93-96.
-
(2001)
Science
, vol.294
, Issue.5540
, pp. 93-96
-
-
Baker, D.1
Sali, A.2
-
57
-
-
0141599428
-
Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor
-
Stamos, J.; Sliwkowski, M. X.; Eigenbrot, C. Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor. J. Biol. Chem., 2002, 277 (48), 46265-46272.
-
(2002)
J. Biol. Chem
, vol.277
, Issue.48
, pp. 46265-46272
-
-
Stamos, J.1
Sliwkowski, M.X.2
Eigenbrot, C.3
-
58
-
-
33745002702
-
An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
-
Zhang, X.; Gureasko, J.; Shen, K.; Cole, P. A.; Kuriyan, J. An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell, 2006, 125 (6), 1137-1149.
-
(2006)
Cell
, vol.125
, Issue.6
, pp. 1137-1149
-
-
Zhang, X.1
Gureasko, J.2
Shen, K.3
Cole, P.A.4
Kuriyan, J.5
-
59
-
-
77956034968
-
-
Accelerys Software Inc, 2.5; Accelerys Software Inc.: San Diego
-
Accelerys Software Inc. Discovery Studio Modeling Environment, 2.5; Accelerys Software Inc.: San Diego, 2009.
-
(2009)
Discovery Studio Modeling Environment
-
-
-
60
-
-
67650500988
-
CHARMM: The biomolecular simulation program
-
Brooks, B. R.; Brooks, C. L.; Mackerell, A. D.; Nilsson, L.; Petrella, R. J.; Roux, B.; Won, Y.; Archontis, G.; Bartels, C.; Boresch, S.; Caflisch, A.; Caves, L.; Cui, Q.; Dinner, A. R.; Feig, M.; Fischer, S.; Gao, J.; Hodoscek, M.; Im, W.; Kuczera, K.; Lazaridis, T.; Ma, J.; Ovchinnikov, V.; Paci, E.; Pastor, R. W.; Post, C. B.; Pu, J. Z.; Schaefer, M.; Tidor, B.; Venable, R. M.; Woodcock, H. L.; Wu, X.; Yang, W.; York, D. M.; Karplus, M. CHARMM: The biomolecular simulation program. J. Comput. Chem., 2009, 30 (10), 1545-1614.
-
(2009)
J. Comput. Chem
, vol.30
, Issue.10
, pp. 1545-1614
-
-
Brooks, B.R.1
Brooks, C.L.2
Mackerell, A.D.3
Nilsson, L.4
Petrella, R.J.5
Roux, B.6
Won, Y.7
Archontis, G.8
Bartels, C.9
Boresch, S.10
Caflisch, A.11
Caves, L.12
Cui, Q.13
Dinner, A.R.14
Feig, M.15
Fischer, S.16
Gao, J.17
Hodoscek, M.18
Im, W.19
Kuczera, K.20
Lazaridis, T.21
Ma, J.22
Ovchinnikov, V.23
Paci, E.24
Pastor, R.W.25
Post, C.B.26
Pu, J.Z.27
Schaefer, M.28
Tidor, B.29
Venable, R.M.30
Woodcock, H.L.31
Wu, X.32
Yang, W.33
York, D.M.34
Karplus, M.35
more..
-
61
-
-
0028454828
-
The development of a simple empirical scoring function to estimate the binding constant for a protein-ligand complex of known three-dimensional structure
-
Bohm, H. J. The development of a simple empirical scoring function to estimate the binding constant for a protein-ligand complex of known three-dimensional structure. J. Comput. Aided Mol. Des., 1994, 8 (3), 243-256.
-
(1994)
J. Comput. Aided Mol. Des
, vol.8
, Issue.3
, pp. 243-256
-
-
Bohm, H.J.1
-
62
-
-
0029294584
-
Molecular recognition of the inhibitor AG-1343 by HIV-1 protease: Conformationally flexible docking by evolutionary programming
-
Gehlhaar, D. K.; Verkhivker, G. M.; Rejto, P. A.; Sherman, C. J.; Fogel, D. B.; Fogel, L. J.; Freer, S. T. Molecular recognition of the inhibitor AG-1343 by HIV-1 protease: conformationally flexible docking by evolutionary programming. Chem. Biol., 1995, 2 (5), 317-324.
-
(1995)
Chem. Biol
, vol.2
, Issue.5
, pp. 317-324
-
-
Gehlhaar, D.K.1
Verkhivker, G.M.2
Rejto, P.A.3
Sherman, C.J.4
Fogel, D.B.5
Fogel, L.J.6
Freer, S.T.7
-
63
-
-
0030255303
-
Scoring noncovalent protein-ligand interactions: A continuous differentiable function tuned to compute binding affinities
-
Jain, A. N. Scoring noncovalent protein-ligand interactions: a continuous differentiable function tuned to compute binding affinities. J. Comput. Aided Mol. Des., 1996, 10 (5), 427-440.
-
(1996)
J. Comput. Aided Mol. Des
, vol.10
, Issue.5
, pp. 427-440
-
-
Jain, A.N.1
-
64
-
-
15244346501
-
LigScore: A novel scoring function for predicting binding affinities
-
Krammer, A.; Kirchhoff, P. D.; Jiang, X.; Venkatachalam, C. M.; Waldman, M. LigScore: a novel scoring function for predicting binding affinities. J. Mol. Graph. Model., 2005, 23 (5), 395-407.
-
(2005)
J. Mol. Graph. Model
, vol.23
, Issue.5
, pp. 395-407
-
-
Krammer, A.1
Kirchhoff, P.D.2
Jiang, X.3
Venkatachalam, C.M.4
Waldman, M.5
-
65
-
-
0033545622
-
A general and fast scoring function for protein-ligand interactions: A simplified potential approach
-
Muegge, I.; Martin, Y. C. A general and fast scoring function for protein-ligand interactions: a simplified potential approach. J. Med. Chem., 1999, 42 (5), 791-804.
-
(1999)
J. Med. Chem
, vol.42
, Issue.5
, pp. 791-804
-
-
Muegge, I.1
Martin, Y.C.2
-
66
-
-
29144499905
-
Working set selection using second order information for training support vector machines
-
Fan, R. E.; Chen, P. H.; Lin, C. J. Working set selection using second order information for training support vector machines. J. Mach. Learn. Res., 2005, 6, 1889-1918.
-
(2005)
J. Mach. Learn. Res
, vol.6
, pp. 1889-1918
-
-
Fan, R.E.1
Chen, P.H.2
Lin, C.J.3
-
67
-
-
33750321978
-
A novel automated lazy learning QSAR (ALL-QSAR) approach: Method development, applications, and virtual screening of chemical databases using validated ALL-QSAR models
-
Zhang, S.; Golbraikh, A.; Oloff, S.; Kohn, H.; Tropsha, A. A novel automated lazy learning QSAR (ALL-QSAR) approach: method development, applications, and virtual screening of chemical databases using validated ALL-QSAR models. J. Chem Inf. Model., 2006, 46 (5), 1984-1995.
-
(2006)
J. Chem Inf. Model
, vol.46
, Issue.5
, pp. 1984-1995
-
-
Zhang, S.1
Golbraikh, A.2
Oloff, S.3
Kohn, H.4
Tropsha, A.5
-
68
-
-
78651084814
-
In silico exploration for identifying structure-activity relationship of MEK inhibition and oral bioavailability for isothiazole derivatives
-
Melagraki, G.; Afantitis, A.; Sarimveis, H.; Igglessi-Markopoulou, O.; Koutentis, P. A.; Kollias, G. In silico exploration for identifying structure-activity relationship of MEK inhibition and oral bioavailability for isothiazole derivatives. Chem. Biol. Drug Des., 2010, 76 (5), 397-406.
-
(2010)
Chem. Biol. Drug Des
, vol.76
, Issue.5
, pp. 397-406
-
-
Melagraki, G.1
Afantitis, A.2
Sarimveis, H.3
Igglessi-Markopoulou, O.4
Koutentis, P.A.5
Kollias, G.6
-
69
-
-
79151478389
-
Ligand-based virtual screening procedure for the prediction and the identification of novel beta-amyloid aggregation inhibitors using Kohonen maps and Counterpropagation Artificial Neural Networks
-
Afantitis, A.; Melagraki, G.; Koutentis, P. A.; Sarimveis, H.; Kollias, G. Ligand-based virtual screening procedure for the prediction and the identification of novel beta-amyloid aggregation inhibitors using Kohonen maps and Counterpropagation Artificial Neural Networks. Eur. J. Med. Chem., 2011, 46 (2), 497-508.
-
(2011)
Eur. J. Med. Chem
, vol.46
, Issue.2
, pp. 497-508
-
-
Afantitis, A.1
Melagraki, G.2
Koutentis, P.A.3
Sarimveis, H.4
Kollias, G.5
-
70
-
-
0036006911
-
Beware of q2!
-
Golbraikh, A.; Tropsha, A. Beware of q2! J. Mol. Graph. Model., 2002, 20 (4), 269-276.
-
(2002)
J. Mol. Graph. Model
, vol.20
, Issue.4
, pp. 269-276
-
-
Golbraikh, A.1
Tropsha, A.2
-
71
-
-
33750321978
-
A novel automated lazy learning QSAR (ALL-QSAR) approach: Method development, applications, and virtual screening of chemical databases using validated ALL-QSAR models
-
Zhang, S. X.; Golbraikh, A.; Oloff, S.; Kohn, H.; Tropsha, A. A novel automated lazy learning QSAR (ALL-QSAR) approach: Method development, applications, and virtual screening of chemical databases using validated ALL-QSAR models. J. Chem Inf. Model., 2006, 46 (5), 1984-1995.
-
(2006)
J. Chem Inf. Model
, vol.46
, Issue.5
, pp. 1984-1995
-
-
Zhang, S.X.1
Golbraikh, A.2
Oloff, S.3
Kohn, H.4
Tropsha, A.5
-
72
-
-
78751614877
-
Fast meta-models for local fusion of multiple predictive models
-
Bonissone, P. P.; Xue, F.; Subbu, R. Fast meta-models for local fusion of multiple predictive models. Appl. Soft. Comput., 2011, 11 (2), 1529-1539.
-
(2011)
Appl. Soft. Comput
, vol.11
, Issue.2
, pp. 1529-1539
-
-
Bonissone, P.P.1
Xue, F.2
Subbu, R.3
-
73
-
-
0033707946
-
Using Bayesian networks to analyze expression data
-
Friedman, N.; Linial, M.; Nachman, I.; Pe'er, D. Using Bayesian networks to analyze expression data. J. Comput. Biol., 2000, 7 (3-4), 601-620.
-
(2000)
J. Comput. Biol
, vol.7
, Issue.3-4
, pp. 601-620
-
-
Friedman, N.1
Linial, M.2
Nachman, I.3
Pe'er, D.4
-
74
-
-
12344259602
-
Advances to Bayesian network inference for generating causal networks from observational biological data
-
Yu, J.; Smith, V. A.; Wang, P. P.; Hartemink, A. J.; Jarvis, E. D. Advances to Bayesian network inference for generating causal networks from observational biological data. Bioinformatics, 2004, 20 (18), 3594-3603.
-
(2004)
Bioinformatics
, vol.20
, Issue.18
, pp. 3594-3603
-
-
Yu, J.1
Smith, V.A.2
Wang, P.P.3
Hartemink, A.J.4
Jarvis, E.D.5
-
75
-
-
0004301669
-
-
Tripos Associates, Tripos Associates: St. Louis, MO
-
Tripos Associates SYBYL Molecular Modeling Software, 8.0; Tripos Associates: St. Louis, MO, 2007.
-
(2007)
SYBYL Molecular Modeling Software, 8.0
-
-
-
76
-
-
79960100263
-
Efficient mapping of ligand migration channel networks in dynamic proteins
-
Lin, T. L.; Song, G. Efficient mapping of ligand migration channel networks in dynamic proteins. Proteins, 2011, 79 (8), 2475-2490.
-
(2011)
Proteins
, vol.79
, Issue.8
, pp. 2475-2490
-
-
Lin, T.L.1
Song, G.2
-
77
-
-
0037180757
-
Inflammation and cancer
-
Coussens, L. M.; Werb, Z. Inflammation and cancer. Nature, 2002, 420 (6917), 860-867.
-
(2002)
Nature
, vol.420
, Issue.6917
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
78
-
-
0025764107
-
Skin problems in advanced and terminal cancer patients
-
De Conno, F.; Ventafridda, V.; Saita, L. Skin problems in advanced and terminal cancer patients. J. Pain Symptom Manage., 1991, 6 (4), 247-256.
-
(1991)
J. Pain Symptom Manage
, vol.6
, Issue.4
, pp. 247-256
-
-
de Conno, F.1
Ventafridda, V.2
Saita, L.3
-
79
-
-
19444388216
-
Hospitalized cancer patients with severe sepsis: Analysis of incidence, mortality, and associated costs of care
-
Williams, M. D.; Braun, L. A.; Cooper, L. M.; Johnston, J.; Weiss, R. V.; Qualy, R. L.; Linde-Zwirble, W. Hospitalized cancer patients with severe sepsis: analysis of incidence, mortality, and associated costs of care. Crit. Care, 2004, 8 (5), R291-R298.
-
(2004)
Crit. Care
, vol.8
, Issue.5
-
-
Williams, M.D.1
Braun, L.A.2
Cooper, L.M.3
Johnston, J.4
Weiss, R.V.5
Qualy, R.L.6
Linde-Zwirble, W.7
-
80
-
-
33846211530
-
Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC)
-
Zick, S. M.; Sen, A.; Feng, Y.; Green, J.; Olatunde, S.; Boon, H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J. Altern. Complement. Med., 2006, 12 (10), 971-980.
-
(2006)
J. Altern. Complement. Med
, vol.12
, Issue.10
, pp. 971-980
-
-
Zick, S.M.1
Sen, A.2
Feng, Y.3
Green, J.4
Olatunde, S.5
Boon, H.6
|