Synthesis and evaluation of geldanamycin-estradiol hybrids

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 9, 1999, Pages 1233-1238

  Kuduk, Scott D ^a   Zheng, Fuzhong F ^b   Sepp Lorenzino, Laura ^b   Rosen, Neal ^b   Danishefsky, Samuel J ^a  

^a Laboratory for Bio Organic Chemsitry   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; ESTRADIOL; ESTROGEN RECEPTOR; GELDANAMYCIN;

ARTICLE; CHEMICAL REACTION; DOWN REGULATION; DRUG STRUCTURE; DRUG SYNTHESIS; HYBRIDIZATION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN TARGETING; REACTION ANALYSIS; STREPTOMYCES HYGROSCOPICUS;

BENZOQUINONES; ENZYME INHIBITORS; ESTRADIOL; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INHIBITORY CONCENTRATION 50; LACTAMS, MACROCYCLIC; MODELS, CHEMICAL; QUINONES; RECEPTORS, ESTROGEN; TUMOR CELLS, CULTURED;

EID: 0003008238     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00185-7     Document Type: Article

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