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Volumn 502, Issue 3, 2001, Pages 93-97

Discovery of a new inhibitor lead of adenovirus proteinase: Steps toward selective, irreversible inhibitors of cysteine proteinases

(7) Pang, Yuan Ping a,b Xu, Kun b Kollmeyer, Thomas M b Perola, Emanuele b McGrath, William J c Green, Dave T c Mangel, Walter F c

a MAYO CLINIC CANCER CENTER (United States)

b MAYO CLINIC (United States)

c BROOKHAVEN NATIONAL LABORATORY (United States)

Author keywords

Antiviral agent; Computational screening; Cysteine proteinase inhibitor; Development; Drug discovery; In silico screening; Molecular docking; Structure based drug design

Indexed keywords

2,4,5,7 TETRANITRO 9 FLUORENONE; CYSTEINE PROTEINASE; FLUORENONE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING SITE; COMPUTER PROGRAM; DATA BASE; EMBRYO DEVELOPMENT; ENZYME INHIBITION; ENZYME MECHANISM; HUMAN ADENOVIRUS; PATHOGENESIS; PRIORITY JOURNAL;

ADENOVIRUSES, HUMAN; ANIMALS; CATTLE; CYSTEINE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; FLUORENES; HUMANS; MOLECULAR STRUCTURE; PAPAIN; RECOMBINANT PROTEINS;

ADENOVIRIDAE; HUMAN ADENOVIRUS;

EID: 0035800608 PISSN: 00145793 EISSN: None Source Type: Journal
DOI: 10.1016/S0014-5793(01)02672-2 Document Type: Article

Times cited : (41)

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