Judging the significance of multiple linear regression models

Journal of Medicinal Chemistry

Volumn 48, Issue 3, 2005, Pages 661-663

  Livingstone, David J ^a,b   Salt, David W ^b  

^a ChemQuest   (United Kingdom)

^b UNIVERSITY OF PORTSMOUTH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CALCULATION; EXPERIMENT; LINEAR REGRESSION ANALYSIS; MOLECULE; RANDOMIZATION; REGRESSION ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL MODEL;

ANTIMYCIN A; LINEAR MODELS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REGRESSION ANALYSIS;

EID: 13444265939     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049111p     Document Type: Article

References (6)

1. Livingstone, D. J.; Salt, D. W. Variable Selection - Spoilt for Choice. In Reviews in Computational Chemistry; Lipkowitz, K., Ed.; Wiley-VCH: Hoboken, NJ, in press.
2. Todeschini, R.; Consonni, V. Handbook of Molecular Descriptors; Wiley-VCH: Mannheim, 2000.
3. Topliss, J. G.; Edwards, R. P. Chance Factors in Studies of Quantitative Structure-Activity Relationships. J. Med. Chem. 1979, 22, 1238-44.
4. Livingstone, D. J. Pattern Recognition Methods for use in Rational Drug Design. In Molecular Design and Modeling: Concepts and Applications; Langone, J. J., Ed.; Academic Press: New York, 1991; Vol. 203 of Methods in Enzymology, pp 613-638.
5. Miller, A. J. Selection of Subsets of Regression Variables. J. R. Statist. Soc. A 1984, 147, 389-425.
6. Selwood, D. L.; Livingstone, D. J.; Comley, J. C. W.; O'Dowd, A. B.; Hudson, A. T.; Jackson, P.; Jandu, K. S.; Rose, V. S.; Stables, J. N. Structure-Activity Relationships of Antifilarial Antimycin Analogues, a Multivariate Pattern Recognition Study. J. Med. Chem. 1990, 33, 136-142.