-
1
-
-
0032552112
-
The stomach is a source of leptin
-
9723619 10.1038/29547 1:CAS:528:DyaK1cXlslemsbo%3D
-
Bado, A.; S. Levasseur, S. Attoub, S. Kermorgant, J.P. Laigneau, M.N. Bortoluzzi, L. Moizo, T. Lehy, M. Guerre-Millo, Y. Le Marchand-Brustel, and M.J. Lewin. 1998. The stomach is a source of leptin. Nature 394: 790-793.
-
(1998)
Nature
, vol.394
, pp. 790-793
-
-
Bado, A.1
Levasseur, S.2
Attoub, S.3
Kermorgant, S.4
Laigneau, J.P.5
Bortoluzzi, M.N.6
Moizo, L.7
Lehy, T.8
Guerre-Millo, M.9
Le Marchand-Brustel, Y.10
Lewin, M.J.11
-
2
-
-
0034640508
-
Activation of downstream signals by the long form of the leptin receptor
-
10799542 10.1074/jbc.275.19.14563 1:CAS:528:DC%2BD3cXjt1Cntrg%3D
-
Banks, A.S.; S.M. Davis, S.H. Bates, and M.G. Myers. 2000. Activation of downstream signals by the long form of the leptin receptor. Journal of Biological Chemistry 275: 14563-14572.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 14563-14572
-
-
Banks, A.S.1
Davis, S.M.2
Bates, S.H.3
Myers, M.G.4
-
3
-
-
0037456304
-
STAT3 signalling is required for leptin regulation of energy balance but not reproduction
-
12594516 10.1038/nature01388 1:CAS:528:DC%2BD3sXht1Kqt7s%3D
-
Bates, S.H.; W.H. Stearns, T.A. Dundon, M. Schubert, A.W. Tso, Y. Wang, A.S. Banks, H.J. Lavery, A.K. Haq, E. Maratos-Flier, B.G. Neel, M.W. Schwartz, and M.G. Myers. 2003. STAT3 signalling is required for leptin regulation of energy balance but not reproduction. Nature 421: 856-859.
-
(2003)
Nature
, vol.421
, pp. 856-859
-
-
Bates, S.H.1
Stearns, W.H.2
Dundon, T.A.3
Schubert, M.4
Tso, A.W.5
Wang, Y.6
Banks, A.S.7
Lavery, H.J.8
Haq, A.K.9
Maratos-Flier, E.10
Neel, B.G.11
Schwartz, M.W.12
Myers, M.G.13
-
4
-
-
33746810001
-
Neuronal PTP1B regulates body weight, adiposity and leptin action
-
16845389 10.1038/nm1435 1:CAS:528:DC%2BD28Xnsl2iur4%3D
-
Bence, K.K.; M. Delibegovic, B. Xue, C.Z. Gorgun, G.S. Hotamisligil, B.G. Neel, and B.B. Kahn. 2006. Neuronal PTP1B regulates body weight, adiposity and leptin action. Nature Medicine 12: 917-924.
-
(2006)
Nature Medicine
, vol.12
, pp. 917-924
-
-
Bence, K.K.1
Delibegovic, M.2
Xue, B.3
Gorgun, C.Z.4
Hotamisligil, G.S.5
Neel, B.G.6
Kahn, B.B.7
-
5
-
-
0032014178
-
Identification of SOCS-3 as a potential mediator of central leptin resistance
-
9660946 10.1016/S1097-2765(00)80062-3
-
Bjørbaek, C.; J.K. Elmquist, J.D. Frantz, S.E. Shoelson, and J.S. Flier. 1998. Identification of SOCS-3 as a potential mediator of central leptin resistance. Molecular Cell 1: 619-625.
-
(1998)
Molecular Cell
, vol.1
, pp. 619-625
-
-
Bjørbaek, C.1
Elmquist, J.K.2
Frantz, J.D.3
Shoelson, S.E.4
Flier, J.S.5
-
6
-
-
0001421697
-
SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985
-
11018044 10.1074/jbc.M007577200 1:STN:280:DC%2BD3M%2FpvVGltA%3D%3D
-
Bjorbak, C.; H.J. Lavery, S.H. Bates, R.K. Olson, S.M. Davis, J.S. Flier, and M.G. Myers. 2000. SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985. Journal of Biological Chemistry 275: 40649-40657.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 40649-40657
-
-
Bjorbak, C.1
Lavery, H.J.2
Bates, S.H.3
Olson, R.K.4
Davis, S.M.5
Flier, J.S.6
Myers, M.G.7
-
7
-
-
0030594830
-
Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance
-
8684156 10.1016/S0140-6736(96)03173-X 1:STN:280:DyaK283psFaqtQ%3D%3D
-
Caro, J.F.; J.W. Kolaczynski, M.R. Nyce, J.P. Ohannesian, I. Opentanova, W.H. Goldman, R.B. Lynn, P.L. Zhang, M.K. Sinha, and R.V. Considine. 1996. Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance. Lancet 348: 159-161.
-
(1996)
Lancet
, vol.348
, pp. 159-161
-
-
Caro, J.F.1
Kolaczynski, J.W.2
Nyce, M.R.3
Ohannesian, J.P.4
Opentanova, I.5
Goldman, W.H.6
Lynn, R.B.7
Zhang, P.L.8
Sinha, M.K.9
Considine, R.V.10
-
8
-
-
0344450708
-
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
-
9537324 10.1038/32911 1:CAS:528:DyaK1cXitlShtrs%3D
-
Clement, K.; C. Vaisse, N. Lahlou, S. Cabrol, V. Pelloux, D. Cassuto, M. Gourmelen, C. Dina, J. Chambaz, J.M. Lacorte, A. Basdevant, P. Bougneres, Y. Lebouc, P. Froguel, and B. Guy-Grand. 1998. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 392: 398-401.
-
(1998)
Nature
, vol.392
, pp. 398-401
-
-
Clement, K.1
Vaisse, C.2
Lahlou, N.3
Cabrol, S.4
Pelloux, V.5
Cassuto, D.6
Gourmelen, M.7
Dina, C.8
Chambaz, J.9
Lacorte, J.M.10
Basdevant, A.11
Bougneres, P.12
Lebouc, Y.13
Froguel, P.14
Guy-Grand, B.15
-
9
-
-
13344295079
-
Serum immunoreactive-leptin concentrations in normal-weight and obese humans
-
8532024 10.1056/NEJM199602013340503 1:STN:280:DyaK287jtlOnsw%3D%3D
-
Considine, R.V.; M.K. Sinha, M.L. Heiman, A. Kriauciunas, T.W. Stephens, M.R. Nyce, J.P. Ohannesian, C.C. Marco, L.J. McKee, and T.L. Bauer. 1996. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. New England Journal of Medicine 334: 292-295.
-
(1996)
New England Journal of Medicine
, vol.334
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
Kriauciunas, A.4
Stephens, T.W.5
Nyce, M.R.6
Ohannesian, J.P.7
Marco, C.C.8
McKee, L.J.9
Bauer, T.L.10
-
10
-
-
84856953003
-
Loss of autophagy in pro-opiomelanocortin neurons perturbs axon growth and causes metabolic dysregulation
-
22285542 10.1016/j.cmet.2011.12.016 1:CAS:528:DC%2BC38XhsVeisb8%3D
-
Coupe, B.; Y. Ishii, M.O. Dietrich, M. Komatsu, T.L. Horvath, and S.G. Bouret. 2012. Loss of autophagy in pro-opiomelanocortin neurons perturbs axon growth and causes metabolic dysregulation. Cell Metabolism 15: 247-255.
-
(2012)
Cell Metabolism
, vol.15
, pp. 247-255
-
-
Coupe, B.1
Ishii, Y.2
Dietrich, M.O.3
Komatsu, M.4
Horvath, T.L.5
Bouret, S.G.6
-
11
-
-
0035942777
-
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
-
11373681 10.1038/35078085 1:CAS:528:DC%2BD3MXkt1ejt7w%3D
-
Cowley, M.A.; J.L. Smart, M. Rubinstein, M.G. Cerdan, S. Diano, T.L. Horvath, R.D. Cone, and M.J. Low. 2001. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 411: 480-484.
-
(2001)
Nature
, vol.411
, pp. 480-484
-
-
Cowley, M.A.1
Smart, J.L.2
Rubinstein, M.3
Cerdan, M.G.4
Diano, S.5
Horvath, T.L.6
Cone, R.D.7
Low, M.J.8
-
12
-
-
24944438230
-
Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus
-
16002529 10.1210/en.2004-1520
-
De Souza, C.T.; E.P. Araujo, S. Bordin, R. Ashimine, R.L. Zollner, A.C. Boschero, M.J. Saad, and L.A. Velloso. 2005. Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus. Endocrinology 146: 4192-4199.
-
(2005)
Endocrinology
, vol.146
, pp. 4192-4199
-
-
De Souza, C.T.1
Araujo, E.P.2
Bordin, S.3
Ashimine, R.4
Zollner, R.L.5
Boschero, A.C.6
Saad, M.J.7
Velloso, L.A.8
-
13
-
-
0030793449
-
Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding
-
9218470 10.1074/jbc.272.29.18304 1:CAS:528:DyaK2sXkslKntrs%3D
-
Devos, R.; Y. Guisez, J. Van der Heyden, D.W. White, M. Kalai, M. Fountoulakis, and G. Plaetinck. 1997. Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding. Journal of Biological Chemistry 272: 18304-18310.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 18304-18310
-
-
Devos, R.1
Guisez, Y.2
Van Der Heyden, J.3
White, D.W.4
Kalai, M.5
Fountoulakis, M.6
Plaetinck, G.7
-
14
-
-
42649145866
-
Megalin mediates the transport of leptin across the blood-CSF barrier
-
17324488 10.1016/j.neurobiolaging.2007.01.008 1:CAS:528: DC%2BD1cXlslSjurY%3D
-
Dietrich, M.O.; C. Spuch, D. Antequera, I. Rodal, J.G. de Yebenes, J.A. Molina, F. Bermejo, and E. Carro. 2008. Megalin mediates the transport of leptin across the blood-CSF barrier. Neurobiology of Aging 29: 902-912.
-
(2008)
Neurobiology of Aging
, vol.29
, pp. 902-912
-
-
Dietrich, M.O.1
Spuch, C.2
Antequera, D.3
Rodal, I.4
De Yebenes, J.G.5
Molina, J.A.6
Bermejo, F.7
Carro, E.8
-
15
-
-
0033931981
-
Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity
-
10862798 10.1172/JCI9842 1:CAS:528:DC%2BD3cXkt1WqsLc%3D
-
El-Haschimi, K.; D.D. Pierroz, S.M. Hileman, C. Bjørbaek, and J.S. Flier. 2000. Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity. The Journal of Clinical Investigation 105: 1827-1832.
-
(2000)
The Journal of Clinical Investigation
, vol.105
, pp. 1827-1832
-
-
El-Haschimi, K.1
Pierroz, D.D.2
Hileman, S.M.3
Bjørbaek, C.4
Flier, J.S.5
-
16
-
-
0033525870
-
Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene
-
10066179 10.1126/science.283.5407.1544 1:CAS:528:DyaK1MXhs1ymtrs%3D
-
Elchebly, M.; P. Payette, E. Michaliszyn, W. Cromlish, S. Collins, A.L. Loy, D. Normandin, A. Cheng, J. Himms-Hagen, C.C. Chan, C. Ramachandran, M.J. Gresser, M.L. Tremblay, and B.P. Kennedy. 1999. Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene. Science 283: 1544-1548.
-
(1999)
Science
, vol.283
, pp. 1544-1548
-
-
Elchebly, M.1
Payette, P.2
Michaliszyn, E.3
Cromlish, W.4
Collins, S.5
Loy, A.L.6
Normandin, D.7
Cheng, A.8
Himms-Hagen, J.9
Chan, C.C.10
Ramachandran, C.11
Gresser, M.J.12
Tremblay, M.L.13
Kennedy, B.P.14
-
17
-
-
0033180532
-
Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area
-
10482243 10.1016/S0896-6273(01)80035-0 1:CAS:528:DyaK1MXmtVWqu7c%3D
-
Elias, C.F.; C. Aschkenasi, C. Lee, J. Kelly, R.S. Ahima, C. Bjorbaek, J.S. Flier, C.B. Saper, and J.K. Elmquist. 1999. Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area. Neuron 23: 775-786.
-
(1999)
Neuron
, vol.23
, pp. 775-786
-
-
Elias, C.F.1
Aschkenasi, C.2
Lee, C.3
Kelly, J.4
Ahima, R.S.5
Bjorbaek, C.6
Flier, J.S.7
Saper, C.B.8
Elmquist, J.K.9
-
18
-
-
0033082380
-
From lesions to leptin: Hypothalamic control of food intake and body weight
-
10069329 10.1016/S0896-6273(00)81084-3 1:CAS:528:DyaK1MXhs12lu7c%3D
-
Elmquist, J.K.; C.F. Elias, and C.B. Saper. 1999. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 22: 221-232.
-
(1999)
Neuron
, vol.22
, pp. 221-232
-
-
Elmquist, J.K.1
Elias, C.F.2
Saper, C.B.3
-
19
-
-
35549009434
-
Differential accessibility of circulating leptin to individual hypothalamic sites
-
17690165 10.1210/en.2007-0655 1:CAS:528:DC%2BD2sXht1aju7bL
-
Faouzi, M.; R. Leshan, M. Bjornholm, T. Hennessey, J. Jones, and H. Munzberg. 2007. Differential accessibility of circulating leptin to individual hypothalamic sites. Endocrinology 148: 5414-5423.
-
(2007)
Endocrinology
, vol.148
, pp. 5414-5423
-
-
Faouzi, M.1
Leshan, R.2
Bjornholm, M.3
Hennessey, T.4
Jones, J.5
Munzberg, H.6
-
20
-
-
0036800760
-
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
-
12393845 1:CAS:528:DC%2BD38XotFGlurk%3D
-
Farooqi, I.S.; G. Matarese, G.M. Lord, J.M. Keogh, E. Lawrence, C. Agwu, V. Sanna, S.A. Jebb, F. Perna, S. Fontana, R.I. Lechler, A.M. DePaoli, and S. O'Rahilly. 2002. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. The Journal of Clinical Investigation 110: 1093-1103.
-
(2002)
The Journal of Clinical Investigation
, vol.110
, pp. 1093-1103
-
-
Farooqi, I.S.1
Matarese, G.2
Lord, G.M.3
Keogh, J.M.4
Lawrence, E.5
Agwu, C.6
Sanna, V.7
Jebb, S.A.8
Perna, F.9
Fontana, S.10
Lechler, R.I.11
Depaoli, A.M.12
O'Rahilly, S.13
-
21
-
-
0026584285
-
The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence
-
1739967 10.1016/0092-8674(92)90190-N 1:CAS:528:DyaK38Xht1Gnsr8%3D
-
Frangioni, J.V.; P.H. Beahm, V. Shifrin, C.A. Jost, and B.G. Neel. 1992. The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence. Cell 68: 545-560.
-
(1992)
Cell
, vol.68
, pp. 545-560
-
-
Frangioni, J.V.1
Beahm, P.H.2
Shifrin, V.3
Jost, C.A.4
Neel, B.G.5
-
22
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
9796811 10.1038/27376 1:CAS:528:DyaK1cXmvFOmsL0%3D
-
Friedman, J.M.; and J.L. Halaas. 1998. Leptin and the regulation of body weight in mammals. Nature 395: 763-770.
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
23
-
-
0033964872
-
Lipodystrophies
-
11126308 10.1016/S0002-9343(99)00414-3 1:STN:280:DC%2BD3M%2Fns1GrtA%3D%3D
-
Garg, A. 2000. Lipodystrophies. American Journal of Medicine 108: 143-152.
-
(2000)
American Journal of Medicine
, vol.108
, pp. 143-152
-
-
Garg, A.1
-
24
-
-
9644303176
-
Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress
-
15465829 10.1074/jbc.C400261200 1:CAS:528:DC%2BD2cXhtVWjs77K
-
Gu, F.; D.T. Nguyen, M. Stuible, N. Dube, M.L. Tremblay, and E. Chevet. 2004. Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress. Journal of Biological Chemistry 279: 49689-49693.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 49689-49693
-
-
Gu, F.1
Nguyen, D.T.2
Stuible, M.3
Dube, N.4
Tremblay, M.L.5
Chevet, E.6
-
25
-
-
0036168190
-
Characterization of short isoforms of the leptin receptor in rat cerebral microvessels and of brain uptake of leptin in mouse models of obesity
-
11861497 10.1210/en.143.3.775 1:CAS:528:DC%2BD38XhvVejurg%3D
-
Hileman, S.M.; D.D. Pierroz, H. Masuzaki, C. Bjørbaek, K. El-Haschimi, W.A. Banks, and J.S. Flier. 2002. Characterization of short isoforms of the leptin receptor in rat cerebral microvessels and of brain uptake of leptin in mouse models of obesity. Endocrinology 143: 775-783.
-
(2002)
Endocrinology
, vol.143
, pp. 775-783
-
-
Hileman, S.M.1
Pierroz, D.D.2
Masuzaki, H.3
Bjørbaek, C.4
El-Haschimi, K.5
Banks, W.A.6
Flier, J.S.7
-
26
-
-
56749112559
-
Endoplasmic reticulum stress induces leptin resistance
-
18755873 10.1124/mol.108.050070 1:CAS:528:DC%2BD1cXhsVGls73L
-
Hosoi, T.; M. Sasaki, T. Miyahara, C. Hashimoto, S. Matsuo, M. Yoshii, and K. Ozawa. 2008. Endoplasmic reticulum stress induces leptin resistance. Molecular Pharmacology 74: 1610-1619.
-
(2008)
Molecular Pharmacology
, vol.74
, pp. 1610-1619
-
-
Hosoi, T.1
Sasaki, M.2
Miyahara, T.3
Hashimoto, C.4
Matsuo, S.5
Yoshii, M.6
Ozawa, K.7
-
27
-
-
33845866857
-
Inflammation and metabolic disorders
-
17167474 10.1038/nature05485 1:CAS:528:DC%2BD28XhtlShtrzK
-
Hotamisligil, G.S. 2006. Inflammation and metabolic disorders. Nature 444: 860-867.
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
28
-
-
3142782772
-
Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3
-
15220914 10.1038/nm1072 1:CAS:528:DC%2BD2cXlt1Gjsbc%3D
-
Howard, J.K.; B.J. Cave, L.J. Oksanen, I. Tzameli, C. Bjørbaek, and J.S. Flier. 2004. Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3. Nature Medicine 10: 734-738.
-
(2004)
Nature Medicine
, vol.10
, pp. 734-738
-
-
Howard, J.K.1
Cave, B.J.2
Oksanen, L.J.3
Tzameli, I.4
Bjørbaek, C.5
Flier, J.S.6
-
29
-
-
0035313069
-
Leptin-induced nuclear translocation of STAT3 immunoreactivity in hypothalamic nuclei involved in body weight regulation
-
11264315 1:CAS:528:DC%2BD3MXjslCls78%3D
-
Hubschle, T.; E. Thom, A. Watson, J. Roth, S. Klaus, and W. Meyerhof. 2001. Leptin-induced nuclear translocation of STAT3 immunoreactivity in hypothalamic nuclei involved in body weight regulation. Journal of Neuroscience 21: 2413-2424.
-
(2001)
Journal of Neuroscience
, vol.21
, pp. 2413-2424
-
-
Hubschle, T.1
Thom, E.2
Watson, A.3
Roth, J.4
Klaus, S.5
Meyerhof, W.6
-
30
-
-
0014004384
-
Diabetes, a new mutation in the mouse
-
5918576 10.1126/science.153.3740.1127 1:STN:280:DyaF2s%2Fhs1WrtA%3D%3D
-
Hummel, K.P.; M.M. Dickie, and D.L. Coleman. 1966. Diabetes, a new mutation in the mouse. Science 153: 1127-1128.
-
(1966)
Science
, vol.153
, pp. 1127-1128
-
-
Hummel, K.P.1
Dickie, M.M.2
Coleman, D.L.3
-
31
-
-
0037201559
-
Protein tyrosine phosphatase 1B negatively regulates leptin signaling in a hypothalamic cell line
-
12354677 10.1016/S0303-7207(02)00178-8 1:CAS:528:DC%2BD38Xnt1ajtrs%3D
-
Kaszubska, W.; H.D. Falls, V.G. Schaefer, D. Haasch, L. Frost, P. Hessler, P.E. Kroeger, D.W. White, M.R. Jirousek, and J.M. Trevillyan. 2002. Protein tyrosine phosphatase 1B negatively regulates leptin signaling in a hypothalamic cell line. Molecular and Cellular Endocrinology 195: 109-118.
-
(2002)
Molecular and Cellular Endocrinology
, vol.195
, pp. 109-118
-
-
Kaszubska, W.1
Falls, H.D.2
Schaefer, V.G.3
Haasch, D.4
Frost, L.5
Hessler, P.6
Kroeger, P.E.7
White, D.W.8
Jirousek, M.R.9
Trevillyan, J.M.10
-
32
-
-
79960951346
-
Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance
-
21803288 10.1016/j.cmet.2011.06.008 1:CAS:528:DC%2BC3MXpsFKitLc%3D
-
Kaushik, S.; J.A. Rodriguez-Navarro, E. Arias, R. Kiffin, S. Sahu, G.J. Schwartz, A.M. Cuervo, and R. Singh. 2011. Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance. Cell Metabolism 14: 173-183.
-
(2011)
Cell Metabolism
, vol.14
, pp. 173-183
-
-
Kaushik, S.1
Rodriguez-Navarro, J.A.2
Arias, E.3
Kiffin, R.4
Sahu, S.5
Schwartz, G.J.6
Cuervo, A.M.7
Singh, R.8
-
33
-
-
51849146897
-
Global burden of obesity in 2005 and projections to 2030
-
18607383 10.1038/ijo.2008.102 1:STN:280:DC%2BD1cngsVamtQ%3D%3D
-
Kelly, T.; W. Yang, C.S. Chen, K. Reynolds, and J. He. 2008. Global burden of obesity in 2005 and projections to 2030. International Journal of Obesity 32: 1431-1437.
-
(2008)
International Journal of Obesity
, vol.32
, pp. 1431-1437
-
-
Kelly, T.1
Yang, W.2
Chen, C.S.3
Reynolds, K.4
He, J.5
-
34
-
-
70349484212
-
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity
-
19808018 10.1016/j.cmet.2009.08.013 1:CAS:528:DC%2BD1MXhsFKltL3K
-
Kleinridders, A.; D. Schenten, A.C. Konner, B.F. Belgardt, J. Mauer, T. Okamura, F.T. Wunderlich, R. Medzhitov, and J.C. Bruning. 2009. MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity. Cell Metabolism 10: 249-259.
-
(2009)
Cell Metabolism
, vol.10
, pp. 249-259
-
-
Kleinridders, A.1
Schenten, D.2
Konner, A.C.3
Belgardt, B.F.4
Mauer, J.5
Okamura, T.6
Wunderlich, F.T.7
Medzhitov, R.8
Bruning, J.C.9
-
35
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
11099404 10.1126/science.290.5497.1717 1:CAS:528:DC%2BD3cXovVOitbw%3D
-
Klionsky, D.J.; and S.D. Emr. 2000. Autophagy as a regulated pathway of cellular degradation. Science 290: 1717-1721.
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
36
-
-
0036828842
-
Regulation of Jak kinases by intracellular leptin receptor sequences
-
12196522 10.1074/jbc.M205148200 1:CAS:528:DC%2BD38XotF2hu7w%3D
-
Kloek, C.; A.K. Haq, S.L. Dunn, H.J. Lavery, A.S. Banks, and M.G. Myers. 2002. Regulation of Jak kinases by intracellular leptin receptor sequences. Journal of Biological Chemistry 277: 41547-41555.
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 41547-41555
-
-
Kloek, C.1
Haq, A.K.2
Dunn, S.L.3
Lavery, H.J.4
Banks, A.S.5
Myers, M.G.6
-
37
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
18191218 10.1016/j.cell.2007.12.018 1:CAS:528:DC%2BD1cXhtFehtb8%3D
-
Levine, B.; and G. Kroemer. 2008. Autophagy in the pathogenesis of disease. Cell 132: 27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
38
-
-
12144289998
-
Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults
-
15070752 10.1073/pnas.0308767101 1:CAS:528:DC%2BD2cXjtFKisrY%3D
-
Licinio, J.; S. Caglayan, M. Ozata, B.O. Yildiz, P.B. de Miranda, F. O'Kirwan, R. Whitby, L. Liang, P. Cohen, S. Bhasin, R.M. Krauss, J.D. Veldhuis, A.J. Wagner, A.M. DePaoli, S.M. McCann, and M.L. Wong. 2004. Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults. Proceedings of the National Academy of Sciences of the United States of America 101: 4531-4536.
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, pp. 4531-4536
-
-
Licinio, J.1
Caglayan, S.2
Ozata, M.3
Yildiz, B.O.4
De Miranda, P.B.5
O'Kirwan, F.6
Whitby, R.7
Liang, L.8
Cohen, P.9
Bhasin, S.10
Krauss, R.M.11
Veldhuis, J.D.12
Wagner, A.J.13
Depaoli, A.M.14
McCann, S.M.15
Wong, M.L.16
-
39
-
-
0034520485
-
Editorial: Leptin as a therapeutic agent - Trials and tribulations
-
11095422 10.1210/jc.85.11.4000 1:CAS:528:DC%2BD3cXotlWntL8%3D
-
Mantzoros, C.S.; and J.S. Flier. 2000. Editorial: leptin as a therapeutic agent - trials and tribulations. Journal of Clinical Endocrinology and Metabolism 85: 4000-4002.
-
(2000)
Journal of Clinical Endocrinology and Metabolism
, vol.85
, pp. 4000-4002
-
-
Mantzoros, C.S.1
Flier, J.S.2
-
40
-
-
33749492425
-
Endoplasmic reticulum stress signaling in disease
-
17015486 10.1152/physrev.00015.2006 1:CAS:528:DC%2BD28Xht1SgtLzN
-
Marciniak, S.J.; and D. Ron. 2006. Endoplasmic reticulum stress signaling in disease. Physiological Reviews 86: 1133-1149.
-
(2006)
Physiological Reviews
, vol.86
, pp. 1133-1149
-
-
Marciniak, S.J.1
Ron, D.2
-
41
-
-
0032900284
-
Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides
-
9916804 10.1038/5070 1:CAS:528:DyaK1MXltlWisg%3D%3D
-
Marsh, D.J.; G. Hollopeter, D. Huszar, R. Laufer, K.A. Yagaloff, S.L. Fisher, P. Burn, and R.D. Palmiter. 1999. Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides. Nature Genetics 21: 119-122.
-
(1999)
Nature Genetics
, vol.21
, pp. 119-122
-
-
Marsh, D.J.1
Hollopeter, G.2
Huszar, D.3
Laufer, R.4
Yagaloff, K.A.5
Fisher, S.L.6
Burn, P.7
Palmiter, R.D.8
-
42
-
-
76049102302
-
Hypothalamic lipotoxicity and the metabolic syndrome
-
19796707 10.1016/j.bbalip.2009.09.016 1:CAS:528:DC%2BC3cXitVejtbo%3D
-
Martinez de Morentin, P.B.; L. Varela, J. Fernø, R. Nogueiras, C. Dieguez, and M. Lopez. 2010. Hypothalamic lipotoxicity and the metabolic syndrome. Biochimica et Biophysica Acta 1801: 350-361.
-
(2010)
Biochimica et Biophysica Acta
, vol.1801
, pp. 350-361
-
-
Martinez De Morentin, P.B.1
Varela, L.2
Fernø, J.3
Nogueiras, R.4
Dieguez, C.5
Lopez, M.6
-
43
-
-
0030866843
-
Nonadipose tissue production of leptin: Leptin as a novel placenta-derived hormone in humans
-
9288733 10.1038/nm0997-1029 1:CAS:528:DyaK2sXlvVyrtL0%3D
-
Masuzaki, H.; Y. Ogawa, N. Sagawa, K. Hosoda, T. Matsumoto, H. Mise, H. Nishimura, Y. Yoshimasa, I. Tanaka, T. Mori, and K. Nakao. 1997. Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. Nature Medicine 3: 1029-1033.
-
(1997)
Nature Medicine
, vol.3
, pp. 1029-1033
-
-
Masuzaki, H.1
Ogawa, Y.2
Sagawa, N.3
Hosoda, K.4
Matsumoto, T.5
Mise, H.6
Nishimura, H.7
Yoshimasa, Y.8
Tanaka, I.9
Mori, T.10
Nakao, K.11
-
45
-
-
80052712323
-
Defective hypothalamic autophagy directs the central pathogenesis of obesity via the IkappaB kinase beta (IKKbeta)/NF-kappaB pathway
-
21784844 10.1074/jbc.M111.254417 1:CAS:528:DC%2BC3MXhtFCju7vN
-
Meng, Q.; and D. Cai. 2011. Defective hypothalamic autophagy directs the central pathogenesis of obesity via the IkappaB kinase beta (IKKbeta)/NF-kappaB pathway. Journal of Biological Chemistry 286: 32324-32332.
-
(2011)
Journal of Biological Chemistry
, vol.286
, pp. 32324-32332
-
-
Meng, Q.1
Cai, D.2
-
46
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
15058305 10.1038/nature02440 1:CAS:528:DC%2BD2cXis1Gks7k%3D
-
Minokoshi, Y.; T. Alquier, N. Furukawa, Y.B. Kim, A. Lee, B. Xue, J. Mu, F. Foufelle, P. Ferre, M.J. Birnbaum, B.J. Stuck, and B.B. Kahn. 2004. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 428: 569-574.
-
(2004)
Nature
, vol.428
, pp. 569-574
-
-
Minokoshi, Y.1
Alquier, T.2
Furukawa, N.3
Kim, Y.B.4
Lee, A.5
Xue, B.6
Mu, J.7
Foufelle, F.8
Ferre, P.9
Birnbaum, M.J.10
Stuck, B.J.11
Kahn, B.B.12
-
47
-
-
12944261926
-
Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activation
-
15581426 10.1186/1471-2202-5-54
-
Mirshamsi, S.; H.A. Laidlaw, K. Ning, E. Anderson, L.A. Burgess, A. Gray, C. Sutherland, and M.L. Ashford. 2004. Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activation. BMC Neuroscience 5: 54.
-
(2004)
BMC Neuroscience
, vol.5
, pp. 54
-
-
Mirshamsi, S.1
Laidlaw, H.A.2
Ning, K.3
Anderson, E.4
Burgess, L.A.5
Gray, A.6
Sutherland, C.7
Ashford, M.L.8
-
48
-
-
0030866876
-
Leptin rapidly lowers food intake and elevates metabolic rates in lean and ob/ob mice
-
9311966 1:CAS:528:DyaK2sXmsV2lsbg%3D
-
Mistry, A.M.; A.G. Swick, and D.R. Romsos. 1997. Leptin rapidly lowers food intake and elevates metabolic rates in lean and ob/ob mice. Journal of Nutrition 127: 2065-2072.
-
(1997)
Journal of Nutrition
, vol.127
, pp. 2065-2072
-
-
Mistry, A.M.1
Swick, A.G.2
Romsos, D.R.3
-
49
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early onset obesity in humans
-
9202122 10.1038/43185 1:CAS:528:DyaK2sXkt1Grtbg%3D
-
Montague, C.T.; I.S. Farooqi, J.P. Whitehead, M.A. Soos, H. Rau, N.J. Wareham, C.P. Sewter, J.E. Digby, S.N. Mohammed, J.A. Hurst, C.H. Cheetham, A.R. Earley, A.H. Barnett, J.B. Prins, and S. O'Rahilly. 1997. Congenital leptin deficiency is associated with severe early onset obesity in humans. Nature 387: 903-908.
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
Farooqi, I.S.2
Whitehead, J.P.3
Soos, M.A.4
Rau, H.5
Wareham, N.J.6
Sewter, C.P.7
Digby, J.E.8
Mohammed, S.N.9
Hurst, J.A.10
Cheetham, C.H.11
Earley, A.R.12
Barnett, A.H.13
Prins, J.B.14
O'Rahilly, S.15
-
50
-
-
3142723983
-
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
-
15208705 10.1038/nm1071 1:CAS:528:DC%2BD2cXlt1GjsbY%3D
-
Mori, H.; R. Hanada, T. Hanada, D. Aki, R. Mashima, H. Nishinakamura, T. Torisu, K.R. Chien, H. Yasukawa, and A. Yoshimura. 2004. Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity. Nature Medicine 10: 739-743.
-
(2004)
Nature Medicine
, vol.10
, pp. 739-743
-
-
Mori, H.1
Hanada, R.2
Hanada, T.3
Aki, D.4
Mashima, R.5
Nishinakamura, H.6
Torisu, T.7
Chien, K.R.8
Yasukawa, H.9
Yoshimura, A.10
-
51
-
-
72249092928
-
Recent advances in understanding leptin signaling and leptin resistance
-
19724019 10.1152/ajpendo.00274.2009 1:CAS:528:DC%2BD1MXhsFOgsbjL
-
Morris, D.L.; and L. Rui. 2009. Recent advances in understanding leptin signaling and leptin resistance. American Journal of Physiology Endocrinology and Metabolism 297: E1247-E1259.
-
(2009)
American Journal of Physiology Endocrinology and Metabolism
, vol.297
-
-
Morris, D.L.1
Rui, L.2
-
52
-
-
9244219587
-
Region-specific leptin resistance within the hypothalamus of diet-induced obese mice
-
15271881 10.1210/en.2004-0726
-
Munzberg, H.; J.S. Flier, and C. Bjørbaek. 2004. Region-specific leptin resistance within the hypothalamus of diet-induced obese mice. Endocrinology 145: 4880-4889.
-
(2004)
Endocrinology
, vol.145
, pp. 4880-4889
-
-
Munzberg, H.1
Flier, J.S.2
Bjørbaek, C.3
-
53
-
-
30344484593
-
Immunohistochemical evidence of functional leptin receptor expression in neuronal and endothelial cells of the rat brain
-
16289843 10.1016/j.neulet.2005.10.031
-
Mutze, J.; J. Roth, R. Gerstberger, K. Matsumura, and T. Hubschle. 2006. Immunohistochemical evidence of functional leptin receptor expression in neuronal and endothelial cells of the rat brain. Neuroscience Letters 394: 105-110.
-
(2006)
Neuroscience Letters
, vol.394
, pp. 105-110
-
-
Mutze, J.1
Roth, J.2
Gerstberger, R.3
Matsumura, K.4
Hubschle, T.5
-
54
-
-
26944442471
-
Molecular mechanisms associated with leptin resistance: N-3 polyunsaturated fatty acids induce alterations in the tight junction of the brain
-
16054080 10.1016/j.cmet.2005.04.004 1:CAS:528:DC%2BD2MXltFant7c%3D
-
Oh-I, S.; H. Shimizu, T. Sato, Y. Uehara, S. Okada, and M. Mori. 2005. Molecular mechanisms associated with leptin resistance: n-3 polyunsaturated fatty acids induce alterations in the tight junction of the brain. Cell Metabolism 1: 331-341.
-
(2005)
Cell Metabolism
, vol.1
, pp. 331-341
-
-
Oh-I, S.1
Shimizu, H.2
Sato, T.3
Uehara, Y.4
Okada, S.5
Mori, M.6
-
55
-
-
0030764741
-
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
-
9311920 10.1126/science.278.5335.135 1:CAS:528:DyaK2sXmsV2ltrw%3D
-
Ollmann, M.M.; B.D. Wilson, Y.K. Yang, J.A. Kerns, Y. Chen, I. Gantz, and G.S. Barsh. 1997. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278: 135-138.
-
(1997)
Science
, vol.278
, pp. 135-138
-
-
Ollmann, M.M.1
Wilson, B.D.2
Yang, Y.K.3
Kerns, J.A.4
Chen, Y.5
Gantz, I.6
Barsh, G.S.7
-
56
-
-
0037148928
-
Leptin-replacement therapy for lipodystrophy
-
11856796 10.1056/NEJMoa012437 1:CAS:528:DC%2BD38XhsFKqu7c%3D
-
Oral, E.A.; V. Simha, E. Ruiz, A. Andewelt, A. Premkumar, P. Snell, A.J. Wagner, A.M. DePaoli, M.L. Reitman, S.I. Taylor, P. Gorden, and A. Garg. 2002. Leptin-replacement therapy for lipodystrophy. New England Journal of Medicine 346: 570-578.
-
(2002)
New England Journal of Medicine
, vol.346
, pp. 570-578
-
-
Oral, E.A.1
Simha, V.2
Ruiz, E.3
Andewelt, A.4
Premkumar, A.5
Snell, P.6
Wagner, A.J.7
Depaoli, A.M.8
Reitman, M.L.9
Taylor, S.I.10
Gorden, P.11
Garg, A.12
-
57
-
-
57849115277
-
Endoplasmic reticulum stress plays a central role in development of leptin resistance
-
19117545 10.1016/j.cmet.2008.12.004 1:CAS:528:DC%2BD1MXptFWquw%3D%3D
-
Ozcan, L.; A.S. Ergin, A. Lu, J. Chung, S. Sarkar, D. Nie, M.G. Myers, and U. Ozcan. 2009. Endoplasmic reticulum stress plays a central role in development of leptin resistance. Cell Metabolism 9: 35-51.
-
(2009)
Cell Metabolism
, vol.9
, pp. 35-51
-
-
Ozcan, L.1
Ergin, A.S.2
Lu, A.3
Chung, J.4
Sarkar, S.5
Nie, D.6
Myers, M.G.7
Ozcan, U.8
-
58
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
7624776 10.1126/science.7624776 1:CAS:528:DyaK2MXntF2ktr4%3D
-
Pelleymounter, M.A.; M.J. Cullen, M.B. Baker, R. Hecht, D. Winters, T. Boone, and F. Collins. 1995. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269: 540-543.
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
Hecht, R.4
Winters, D.5
Boone, T.6
Collins, F.7
-
59
-
-
66149118129
-
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
-
19116375 10.1152/ajpendo.90377.2008 1:CAS:528:DC%2BD1MXlvFags7w%3D
-
Posey, K.A.; D.J. Clegg, R.L. Printz, J. Byun, G.J. Morton, A. Vivekanandan-Giri, S. Pennathur, D.G. Baskin, J.W. Heinecke, S.C. Woods, M.W. Schwartz, and K.D. Niswender. 2009. Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. American Journal of Physiology Endocrinology and Metabolism 296: E1003-E1012.
-
(2009)
American Journal of Physiology Endocrinology and Metabolism
, vol.296
-
-
Posey, K.A.1
Clegg, D.J.2
Printz, R.L.3
Byun, J.4
Morton, G.J.5
Vivekanandan-Giri, A.6
Pennathur, S.7
Baskin, D.G.8
Heinecke, J.W.9
Woods, S.C.10
Schwartz, M.W.11
Niswender, K.D.12
-
60
-
-
84859416906
-
Role of hypothalamic proopiomelanocortin neuron autophagy in the control of appetite and leptin response
-
22334718 10.1210/en.2011-1882 1:CAS:528:DC%2BC38XlsVSmsL8%3D
-
Quan, W.; H.K. Kim, E.Y. Moon, S.S. Kim, C.S. Choi, M. Komatsu, Y.T. Jeong, M.K. Lee, K.W. Kim, M.S. Kim, and M.S. Lee. 2012. Role of hypothalamic proopiomelanocortin neuron autophagy in the control of appetite and leptin response. Endocrinology 153: 1817-1826.
-
(2012)
Endocrinology
, vol.153
, pp. 1817-1826
-
-
Quan, W.1
Kim, H.K.2
Moon, E.Y.3
Kim, S.S.4
Choi, C.S.5
Komatsu, M.6
Jeong, Y.T.7
Lee, M.K.8
Kim, K.W.9
Kim, M.S.10
Lee, M.S.11
-
62
-
-
0029881125
-
Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
-
8616722 10.1038/nm0596-589 1:CAS:528:DyaK28Xislyhs7Y%3D
-
Schwartz, M.W.; E. Peskind, M. Raskind, E.J. Boyko, and D. Porte. 1996. Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans. Nature Medicine 2: 589-593.
-
(1996)
Nature Medicine
, vol.2
, pp. 589-593
-
-
Schwartz, M.W.1
Peskind, E.2
Raskind, M.3
Boyko, E.J.4
Porte, D.5
-
63
-
-
0034611732
-
Central nervous system control of food intake
-
10766253 1:CAS:528:DC%2BD3cXis1Grur4%3D
-
Schwartz, M.W.; S.C. Woods, D. Porte, R.J. Seeley, and D.G. Baskin. 2000. Central nervous system control of food intake. Nature 404: 661-671.
-
(2000)
Nature
, vol.404
, pp. 661-671
-
-
Schwartz, M.W.1
Woods, S.C.2
Porte, D.3
Seeley, R.J.4
Baskin, D.G.5
-
64
-
-
0030942844
-
The leptin receptor
-
9102398 1:CAS:528:DyaK2sXhvVOnsb4%3D
-
Tartaglia, L.A. 1997. The leptin receptor. Journal of Biological Chemistry 272: 6093-6096.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 6093-6096
-
-
Tartaglia, L.A.1
-
65
-
-
56749176947
-
One step at a time: Endoplasmic reticulum-associated degradation
-
19002207 10.1038/nrm2546 1:CAS:528:DC%2BD1cXhsVWhurjI
-
Vembar, S.S.; and J.L. Brodsky. 2008. One step at a time: endoplasmic reticulum-associated degradation. Nature Reviews Molecular Cell Biology 9: 944-957.
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, pp. 944-957
-
-
Vembar, S.S.1
Brodsky, J.L.2
-
66
-
-
60849120123
-
HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms
-
19017730 10.1152/ajpendo.90513.2008 1:CAS:528:DC%2BD1MXitVaqsLw%3D
-
White, C.L.; A. Whittington, M.J. Barnes, Z. Wang, G.A. Bray, and C.D. Morrison. 2009. HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms. American Journal of Physiology Endocrinology and Metabolism 296: E291-E299.
-
(2009)
American Journal of Physiology Endocrinology and Metabolism
, vol.296
-
-
White, C.L.1
Whittington, A.2
Barnes, M.J.3
Wang, Z.4
Bray, G.A.5
Morrison, C.D.6
-
67
-
-
70349507353
-
Central administration of an endoplasmic reticulum stress inducer inhibits the anorexigenic effects of leptin and insulin
-
10.1038/oby.2009.194 1:CAS:528:DC%2BD1MXhtFOhsrrP
-
Won, J.C.; P.G. Jang, C. Namkoong, E.H. Koh, S.K. Kim, J.Y. Park, K.U. Lee, and M.S. Kim. 2009. Central administration of an endoplasmic reticulum stress inducer inhibits the anorexigenic effects of leptin and insulin. Obesity (Silver Spring) 17: 1861-1865.
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 1861-1865
-
-
Won, J.C.1
Jang, P.G.2
Namkoong, C.3
Koh, E.H.4
Kim, S.K.5
Park, J.Y.6
Lee, K.U.7
Kim, M.S.8
-
68
-
-
47249148827
-
Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo
-
18281274 10.1074/jbc.M800061200 1:CAS:528:DC%2BD1cXlvFOqu7o%3D
-
Zabolotny, J.M.; Y.B. Kim, L.A. Welsh, E.E. Kershaw, B.G. Neel, and B.B. Kahn. 2008. Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo. Journal of Biological Chemistry 283: 14230-14241.
-
(2008)
Journal of Biological Chemistry
, vol.283
, pp. 14230-14241
-
-
Zabolotny, J.M.1
Kim, Y.B.2
Welsh, L.A.3
Kershaw, E.E.4
Neel, B.G.5
Kahn, B.B.6
-
69
-
-
11844263385
-
High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex
-
15649487 10.1016/j.expneurol.2004.10.011 1:CAS:528:DC%2BD2MXksFKjuw%3D%3D
-
Zhang, X.; F. Dong, J. Ren, M.J. Driscoll, and B. Culver. 2005. High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex. Experimental Neurology 191: 318-325.
-
(2005)
Experimental Neurology
, vol.191
, pp. 318-325
-
-
Zhang, X.1
Dong, F.2
Ren, J.3
Driscoll, M.J.4
Culver, B.5
-
70
-
-
52949096557
-
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity
-
18854155 10.1016/j.cell.2008.07.043 1:CAS:528:DC%2BD1cXht1Gkt7nP
-
Zhang, X.; G. Zhang, H. Zhang, M. Karin, H. Bai, and D. Cai. 2008. Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell 135: 61-73.
-
(2008)
Cell
, vol.135
, pp. 61-73
-
-
Zhang, X.1
Zhang, G.2
Zhang, H.3
Karin, M.4
Bai, H.5
Cai, D.6
-
71
-
-
0034456535
-
Differential regulation of leptin transport by the choroid plexus and blood-brain barrier and high affinity transport systems for entry into hypothalamus and across the blood-cerebrospinal fluid barrier
-
10746647 10.1210/en.141.4.1434 1:CAS:528:DC%2BD3cXisFOktbY%3D
-
Zlokovic, B.V.; S. Jovanovic, W. Miao, S. Samara, S. Verma, and C.L. Farrell. 2000. Differential regulation of leptin transport by the choroid plexus and blood-brain barrier and high affinity transport systems for entry into hypothalamus and across the blood-cerebrospinal fluid barrier. Endocrinology 141: 1434-1441.
-
(2000)
Endocrinology
, vol.141
, pp. 1434-1441
-
-
Zlokovic, B.V.1
Jovanovic, S.2
Miao, W.3
Samara, S.4
Verma, S.5
Farrell, C.L.6
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