Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding

Journal of Biological Chemistry

Volumn 272, Issue 29, 1997, Pages 18304-18310

  Devos, René ^a   Guisez, Yves ^a   Van Der Heyden, José ^a   White, David W ^b   Kalai, Michael ^a   Fountoulakis, Michael ^c   Plaetinck, Geert ^a  

^a Roche Research   (Belgium)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; MEMBRANE PROTEIN;

AFFINITY CHROMATOGRAPHY; AMINO ACID COMPOSITION; ANIMAL CELL; ARTICLE; CROSS LINKING; DIMERIZATION; GEL FILTRATION CHROMATOGRAPHY; GENETIC TRANSFECTION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; RECEPTOR BINDING; STOICHIOMETRY;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; CARRIER PROTEINS; CELL LINE; COS CELLS; CROSS-LINKING REAGENTS; CYTOPLASM; DIMERIZATION; HUMANS; KINETICS; LEPTIN; MOLECULAR SEQUENCE DATA; OBESITY; PEPTIDE FRAGMENTS; PROTEINS; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; SPODOPTERA; TRANSFECTION;

ANIMALIA; INSECTA; UNIDENTIFIED BACULOVIRUS;

EID: 0030793449     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.29.18304     Document Type: Article

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