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Volumn 63, Issue 5, 2013, Pages 228-236

Induction of inflammation, DNA damage and apoptosis in rat heart after oral exposure to zinc oxide nanoparticles and the cardioprotective role of α-lipoic acid and vitamin e

Author keywords

deoxyribonucleic acid; vitamin E; zinc oxide nanoparticles; lipoic acid

Indexed keywords

ALPHA TOCOPHEROL; C REACTIVE PROTEIN; CALCIUM; CASPASE 3; CREATINE KINASE MB; INTERLEUKIN 6; MYOGLOBIN; NANOPARTICLE; NITRIC OXIDE; THIOCTIC ACID; TROPONIN T; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; ZINC OXIDE;

EID: 84878305342     PISSN: 21949379     EISSN: 21949387     Source Type: Journal    
DOI: 10.1055/s-0033-1334923     Document Type: Article
Times cited : (36)

References (74)
  • 1
    • 31944451232 scopus 로고    scopus 로고
    • Toxic potential of materials at the nano-level
    • Nel A., Xia T., Madler L. et al. Toxic potential of materials at the nano-level. Sci: 2006; 311 622 627
    • (2006) Sci , vol.311 , pp. 622-627
    • Nel, A.1    Xia, T.2    Madler, L.3
  • 2
    • 33947520683 scopus 로고    scopus 로고
    • U.S. nanotechnology. Health and safety research slated for sizable gains
    • Service R. F. U.S. nanotechnology. Health and safety research slated for sizable gains. Sci: 2007; 315 926
    • (2007) Sci , vol.315 , pp. 926
    • Service, R.F.1
  • 3
    • 60749122689 scopus 로고    scopus 로고
    • Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation. Environ
    • Lu S., Duffin R., Poland C. et al. Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation. Environ. Health Perspect: 2009; 117 241 247
    • (2009) Health Perspect , vol.117 , pp. 241-247
    • Lu, S.1    Duffin, R.2    Poland, C.3
  • 4
    • 67649491055 scopus 로고    scopus 로고
    • Understanding biophysicochemical interactions at the nano-bio interface
    • Nel A. E., Madler L., Velegol D. et al. Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater: 2009; 8 543 557
    • (2009) Nat Mater , vol.8 , pp. 543-557
    • Nel, A.E.1    Madler, L.2    Velegol, D.3
  • 5
    • 77949780454 scopus 로고    scopus 로고
    • Areview of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity
    • Johnston H. J., Hutchison G., Christensen F. M. et al. Areview of the in vivo and in vitro toxicity of silver and gold particulates: particle attributes and biological mechanisms responsible for the observed toxicity. Crit Rev Toxicol: 2010; 40 328 346
    • (2010) Crit Rev Toxicol , vol.40 , pp. 328-346
    • Johnston, H.J.1    Hutchison, G.2    Christensen, F.M.3
  • 6
    • 0141594997 scopus 로고    scopus 로고
    • The potential environmental impact of engineered nanomaterials
    • DOI 10.1038/nbt875
    • Colvin V. L. The potential environmental impact of engineered nanomaterials. Nat Biotechnol: 2003; 21 1166 1170 (Pubitemid 37203347)
    • (2003) Nature Biotechnology , vol.21 , Issue.10 , pp. 1166-1170
    • Colvin, V.L.1
  • 7
    • 33845217749 scopus 로고    scopus 로고
    • Combustion-derived nanoparticles: A review of their toxicology following inhalation exposure
    • Donaldson K., Tran L., Jimenez L. A. et al. Combustion-derived nanoparticles: A review of their toxicology following inhalation exposure. Part Fibre Toxicol: 2005; 2 10
    • (2005) Part Fibre Toxicol , vol.2 , pp. 10
    • Donaldson, K.1    Tran, L.2    Jimenez, L.A.3
  • 9
    • 40949113637 scopus 로고    scopus 로고
    • Toxicity of nanosized and bulk ZnO, CuO and TiO2 to bacteria Vibrio fischeri and crustaceans Daphnia magna and Thamnocephalus platyurus
    • Heinlaan M., Ivask A., Blinova I. et al. Toxicity of nanosized and bulk ZnO, CuO and TiO2 to bacteria Vibrio fischeri and crustaceans Daphnia magna and Thamnocephalus platyurus. Chemosphere: 2008; 71 1308 1316
    • (2008) Chemosphere , vol.71 , pp. 1308-1316
    • Heinlaan, M.1    Ivask, A.2    Blinova, I.3
  • 10
    • 34147158989 scopus 로고    scopus 로고
    • Induction of inflammation in vascular endothelial cells by metal oxide nanoparticles: Effect of particle composition
    • DOI 10.1289/ehp.8497
    • Gojova A., Guo B., Kota R. S. et al. Induction of inflammation in vascular endothelial cells by metal oxide nanoparticles: effect of particle composition. Environ Health Perspect: 2007; 115 403 409 (Pubitemid 46554439)
    • (2007) Environmental Health Perspectives , vol.115 , Issue.3 , pp. 403-409
    • Gojova, A.1    Guo, B.2    Kota, R.S.3    Rutledge, J.C.4    Kennedy, I.M.5    Barakat, A.I.6
  • 11
    • 58149185440 scopus 로고    scopus 로고
    • Toxicity of nano- and micro-sized ZnO particles in human lung epithelial cells
    • Lin W. S., Xu Y., Huang C. C. et al. Toxicity of nano- and micro-sized ZnO particles in human lung epithelial cells. J Nanopart Res: 2009; 11 25 29
    • (2009) J Nanopart Res , vol.11 , pp. 25-29
    • Lin, W.S.1    Xu, Y.2    Huang, C.C.3
  • 12
    • 84864851861 scopus 로고    scopus 로고
    • Toxicity of zinc oxide nanoparticles through oral route
    • Pasupuleti S., Alapati S., Ganapathy S. et al. Toxicity of zinc oxide nanoparticles through oral route. Toxicol Ind Health: 2012; 28 675 686
    • (2012) Toxicol Ind Health , vol.28 , pp. 675-686
    • Pasupuleti, S.1    Alapati, S.2    Ganapathy, S.3
  • 13
    • 0034948899 scopus 로고    scopus 로고
    • Modulation of postoperative immune and inflammatory response by immune-enhancing enteral diet in gastrointestinal cancer patients
    • Wu G. H., Zhang Y. W., Wu Z. H. Modulation of postoperative immune and inflammatory response by immune-enhancing enteral diet in gastrointestinal cancer patients. World J Gastroentero: 2001; 7 357 362 (Pubitemid 32586520)
    • (2001) World Journal of Gastroenterology , vol.7 , Issue.3 , pp. 357-362
    • Wu, G.H.1    Zhang, Y.W.2    Wu, Z.H.3
  • 14
    • 26444581298 scopus 로고    scopus 로고
    • Quercetin decreases oxidative stress, NF-κB activation, and iNOS overexpression in liver of streptozotocin-induced diabetic rats
    • Dias A. S., Porawski M., Alonso M. et al. Quercetin Decreases Oxidative Stress, NF-κB Activation, and iNOS Overexpression in Liver of Streptozotocin-Induced Diabetic Rats. J Nutr: 2005; 135 2299 2304 (Pubitemid 41429581)
    • (2005) Journal of Nutrition , vol.135 , Issue.10 , pp. 2299-2304
    • Dias, A.S.1    Porawski, M.2    Alonso, M.3    Marroni, N.4    Collado, P.S.5    Gonzalez-Gallego, J.6
  • 15
    • 84878331501 scopus 로고    scopus 로고
    • Quercetin supplementation suppresses the secretion of pro-inflammatory cytokines in the lungs of Mongolian gerbils and in A549 cells exposed to benzo[a]pyrene alone or in combination with β-carotene: In vivo and ex vivo studies
    • (in press)
    • Chana S. T., Chuangb C. H., Yehb C. L. et al. Quercetin supplementation suppresses the secretion of pro-inflammatory cytokines in the lungs of Mongolian gerbils and in A549 cells exposed to benzo[a]pyrene alone or in combination with β-carotene: in vivo and ex vivo studies. J Nutr Biochem: 2011; (in press)
    • (2011) J Nutr Biochem
    • Chana, S.T.1    Chuangb, C.H.2    Yehb, C.L.3
  • 16
    • 33644664987 scopus 로고    scopus 로고
    • α-lipoic acid - The drug of the future
    • Bilska A., Wlodek L. α-lipoic acid - the drug of the future? Pharmacol Rep: 2005; 57 570 577
    • (2005) Pharmacol Rep , vol.57 , pp. 570-577
    • Bilska, A.1    Wlodek, L.2
  • 17
    • 18144410537 scopus 로고    scopus 로고
    • Substantial inhibition of chromate induced DNA-protein crosslink formation in vivo by α-lipoic acid
    • DOI 10.1016/j.etap.2004.10.006
    • Budhwar R., Kumar S. Substantial inhibition of chromate induced DNA-protein crosslink formation in vivo by alpha-α-lipoic acid. Environ. Toxicol Pharmacol: 2005; 20 246 249 (Pubitemid 40615385)
    • (2005) Environmental Toxicology and Pharmacology , vol.20 , Issue.1 , pp. 246-249
    • Budhwar, R.1    Kumar, S.2
  • 19
    • 0029006347 scopus 로고
    • Effect of alpha-α-lipoic acid and ihydroα-lipoic acid on ischemia/reperfusion injury of the heart and heart mitochondria
    • Schonheit K., Gille L., Nohl H. Effect of alpha-α-lipoic acid and ihydroα-lipoic acid on ischemia/reperfusion injury of the heart and heart mitochondria. Biochem Biophys Acta: 1995; 1271 335 342
    • (1995) Biochem Biophys Acta , vol.1271 , pp. 335-342
    • Schonheit, K.1    Gille, L.2    Nohl, H.3
  • 20
    • 0141757175 scopus 로고    scopus 로고
    • Induction of endogenous antioxidants and phase 2 enzymes by α-lipoic acid in rat cardiac H9C2 cells: Protection against oxidative injury
    • DOI 10.1016/j.bbrc.2003.09.110
    • Cao Z., Tsang M., Zhao H. et al. Induction of endogenous anti-oxidants and phase 2 enzymes by alpha-α-lipoic acid in rat cardiac H9C2 cells: protection against oxidative injury. Biochem Biophys Res Commun: 2003; 310 979 985 (Pubitemid 37188719)
    • (2003) Biochemical and Biophysical Research Communications , vol.310 , Issue.3 , pp. 979-985
    • Cao, Z.1    Tsang, M.2    Zhao, H.3    Li, Y.4
  • 21
    • 70350519368 scopus 로고    scopus 로고
    • Cardioprotective Effects of Alpha-α-lipoic Acid on Myocardial Reperfusion Injury: Suppression of Reactive Oxygen Species Generation and Activation of Mitogen-Activated Protein Kinase
    • Oh S. K., Yun K. H., Yoo N. J. et al. Cardioprotective Effects of Alpha-α-lipoic Acid on Myocardial Reperfusion Injury: Suppression of Reactive Oxygen Species Generation and Activation of Mitogen-Activated Protein Kinase. Korean Circ J: 2009; 39 359 366
    • (2009) Korean Circ J , vol.39 , pp. 359-366
    • Oh, S.K.1    Yun, K.H.2    Yoo, N.J.3
  • 22
    • 13244282987 scopus 로고    scopus 로고
    • Tocotrienols: Constitutional effects in aging and disease
    • Schaffer S., Müller W. E., Eckert G. P. Tocotrienols: constitutional effects in aging and disease. J Nutr: 2005; 135 151 154 (Pubitemid 40194470)
    • (2005) Journal of Nutrition , vol.135 , Issue.2 , pp. 151-154
    • Schaffer, S.1    Muller, W.E.2    Eckert, G.P.3
  • 23
    • 35448939592 scopus 로고    scopus 로고
    • Modulation of signal transduction by vitamin e
    • Zingg J. M. Modulation of signal transduction by vitamin E. Molecular Aspects of Medicine: 2007; 28 481 506
    • (2007) Molecular Aspects of Medicine , vol.28 , pp. 481-506
    • Zingg, J.M.1
  • 24
    • 77956234558 scopus 로고    scopus 로고
    • Inhibition of Inflammation and Carcinogenesis in the Lung and Colon by Tocopherols
    • Yang C. S., Lu G., Ju J. et al. Inhibition of Inflammation and Carcinogenesis in the Lung and Colon by Tocopherols. Ann N Y Acad Sci: 2010; 1203 29 34
    • (2010) Ann N y Acad Sci , vol.1203 , pp. 29-34
    • Yang, C.S.1    Lu, G.2    Ju, J.3
  • 25
    • 79952053160 scopus 로고    scopus 로고
    • δ-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens
    • Qureshi A. A., Reis J. C., Qureshi N. et al. δ-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens. Lipids in Health and Disease: 2011; 10 39 58
    • (2011) Lipids in Health and Disease , vol.10 , pp. 39-58
    • Qureshi, A.A.1    Reis, J.C.2    Qureshi, N.3
  • 26
    • 80053241276 scopus 로고    scopus 로고
    • Vitamin e has a dual effect of anti-inflammatory and antioxidant activities in acetic acid - Induced ulcerative colitis in rats
    • Tahan G., Aytac E., Aytekin H. et al. Vitamin E has a dual effect of anti-inflammatory and antioxidant activities in acetic acid - induced ulcerative colitis in rats. Can J Surg: 2011; 54 333 338
    • (2011) Can J Surg , vol.54 , pp. 333-338
    • Tahan, G.1    Aytac, E.2    Aytekin, H.3
  • 27
    • 79959368071 scopus 로고    scopus 로고
    • Tocotrienol-Rich Fraction Prevents Cell Cycle Arrest and Elongates Telomere Length in Senescent Human Diploid Fibroblasts
    • Makpol S., Durani L. W., Chua K. H. et al. Tocotrienol-Rich Fraction Prevents Cell Cycle Arrest and Elongates Telomere Length in Senescent Human Diploid Fibroblasts. J Biomed Biotechnol: 2011; 2011 506171
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 506171
    • Makpol, S.1    Durani, L.W.2    Chua, K.H.3
  • 29
    • 0041347741 scopus 로고    scopus 로고
    • Effect of alpha lipoic acid on intracerebroventricular streptozotocin model of cognitive impairment in rats
    • DOI 10.1016/S0924-977X(03)00008-7
    • Sharma M., Gupta Y. K. Effect of alpha α-lipoic acid on intracerebroventricular streptozotocin model of cognitive impairment in rats. Eur Neuropsychopharmacol: 2003; 13 241 247 (Pubitemid 36904050)
    • (2003) European Neuropsychopharmacology , vol.13 , Issue.4 , pp. 241-247
    • Sharma, M.1    Gupta, Y.K.2
  • 30
    • 70349679319 scopus 로고    scopus 로고
    • Effects of Pycnogenol and vitamin e on cognitive deficits and oxidative damage induced by intracerebroventricular streptozotocin in rats
    • Ishrat T., Parveen K., Hoda M. N. et al. Effects of Pycnogenol and vitamin E on cognitive deficits and oxidative damage induced by intracerebroventricular streptozotocin in rats. Behav Pharmacol: 2009; 20 567 575
    • (2009) Behav Pharmacol , vol.20 , pp. 567-575
    • Ishrat, T.1    Parveen, K.2    Hoda, M.N.3
  • 31
    • 33847750701 scopus 로고    scopus 로고
    • IL-6 Determination in Serum of Kidney Graft Recipients by a New Bedside Test: Its Diagnostic Relevance
    • DOI 10.1016/j.transproceed.2006.12.015, PII S0041134506015624
    • Kaden J. IL-6 determination in serum of kidney graft recipients by a new bedside test: its diagnostic relevance. Transplant Proc: 2007; 39 511 513 (Pubitemid 46386218)
    • (2007) Transplantation Proceedings , vol.39 , Issue.2 , pp. 511-513
    • Kaden, J.1
  • 32
    • 77951217259 scopus 로고    scopus 로고
    • Gold nanoparticle-based signal augmentation of quartz crystal microbalance immunosensor measuring C-reactive protein
    • Kim N., Kim Y. J., Cho D. K. Gold nanoparticle-based signal augmentation of quartz crystal microbalance immunosensor measuring C-reactive protein. Curr Appl Phys: 2010; 10 1227 1230
    • (2010) Curr Appl Phys , vol.10 , pp. 1227-1230
    • Kim, N.1    Kim, Y.J.2    Cho, D.K.3
  • 34
    • 0029033537 scopus 로고
    • Nitrite and Nitrate Determination in Plasma: A Critical Evaluation
    • Moshage H., Kok B., Uuizenga J. R. et al. Nitrite and Nitrate Determination in Plasma: A Critical Evaluation. Clin Chim: 1995; 41 892 896
    • (1995) Clin Chim , vol.41 , pp. 892-896
    • Moshage, H.1    Kok, B.2    Uuizenga, J.R.3
  • 38
    • 84860432043 scopus 로고    scopus 로고
    • Induction of oxidative stress, DNA damage and apoptosis in mouse liver after sub-acute oral exposure to zinc oxide nanoparticles
    • Epub 2011 Dec 17
    • Sharma V., Singh P., Pandey A. K. et al. Induction of oxidative stress, DNA damage and apoptosis in mouse liver after sub-acute oral exposure to zinc oxide nanoparticles. Mutat Res: 2012; 745 84 91 Epub 2011 Dec 17
    • (2012) Mutat Res , vol.745 , pp. 84-91
    • Sharma, V.1    Singh, P.2    Pandey, A.K.3
  • 39
    • 84859706392 scopus 로고    scopus 로고
    • Zinc oxide nanoparticles cause nephrotoxicity and kidney metabolism alterations in rats
    • Yan G., Huang Y., Bu Q. et al. Zinc oxide nanoparticles cause nephrotoxicity and kidney metabolism alterations in rats. J Environ Sci Health A Tox Hazard Subst Environ Eng: 2012; 47 577 588
    • (2012) J Environ Sci Health A Tox Hazard Subst Environ Eng , vol.47 , pp. 577-588
    • Yan, G.1    Huang, Y.2    Bu, Q.3
  • 40
    • 0019514113 scopus 로고
    • Several conditions causing elevation of serum CK-MB and CK-BB
    • Tsung S. H. Several conditions causing elevation of serum CK-MB and CK-BB. Am J Clin Pathol: 1981; 75 711 715
    • (1981) Am J Clin Pathol , vol.75 , pp. 711-715
    • Tsung, S.H.1
  • 41
    • 0024336693 scopus 로고
    • Unstable angina - A classification
    • Braunwald E. Unstable angina - a classification. Circulation: 1989; 80 410 414
    • (1989) Circulation , vol.80 , pp. 410-414
    • Braunwald, E.1
  • 42
    • 0026651887 scopus 로고
    • The prognostic value of serum troponin T in unstable angina
    • Hamm C. W., Ravkilde J., Gerhardt W. et al. The prognostic value of serum troponin T in unstable angina. N Engl J Med: 1992; 327 146 150
    • (1992) N Engl J Med , vol.327 , pp. 146-150
    • Hamm, C.W.1    Ravkilde, J.2    Gerhardt, W.3
  • 43
    • 79955538559 scopus 로고    scopus 로고
    • Comparison between Cardiac Troponin i and CK-MB Mass in Acute Coronary Syndrome without ST Elevation
    • Santos E. S., Baltar V. T., Pereira M. P. et al. Comparison between Cardiac Troponin I and CK-MB Mass in Acute Coronary Syndrome without ST Elevation. Arq Bras Cardiol: 2011; 96 179 187
    • (2011) Arq Bras Cardiol , vol.96 , pp. 179-187
    • Santos, E.S.1    Baltar, V.T.2    Pereira, M.P.3
  • 44
    • 0031299325 scopus 로고    scopus 로고
    • Clinical utility of cardiac troponin i and cardiac troponin T measurements
    • Adamcova M., Kokstein Z., Vavrova J. Clinical utility of cardiac troponin I and cardiac troponin T measurements. Acta Medica: 1997; 40 83 87
    • (1997) Acta Medica , vol.40 , pp. 83-87
    • Adamcova, M.1    Kokstein, Z.2    Vavrova, J.3
  • 45
    • 79952466981 scopus 로고    scopus 로고
    • Erythrocyte Transketolase Activity, Markers of Cardiac Dysfunction and the Diagnosis of Infantile Beriberi
    • Soukaloun D., Lee S. J., Chamberlain K. et al. Erythrocyte Transketolase Activity, Markers of Cardiac Dysfunction and the Diagnosis of Infantile Beriberi. PLoS Negl Trop Dis: 2011; 5 e971 e981
    • (2011) PLoS Negl Trop Dis , vol.5
    • Soukaloun, D.1    Lee, S.J.2    Chamberlain, K.3
  • 46
    • 0032911825 scopus 로고    scopus 로고
    • Creatine kinase and its CK-MB isoenzyme: The conventional marker for the diagnosis of acute myocardial infarction
    • DOI 10.1016/S0736-4679(98)00129-2, PII S0736467998001292
    • Robinson D. J., Christenson R. H. Creatine kinase and its CK-MB isoenzyme: the conventional marker for the diagnosis of acute myocardial infarction. J Emerg Med: 1999; 17 95 104 (Pubitemid 29058823)
    • (1999) Journal of Emergency Medicine , vol.17 , Issue.1 , pp. 95-104
    • Robinson, D.J.1    Christenson, R.H.2
  • 47
    • 33846451042 scopus 로고    scopus 로고
    • Cardiac troponins in the intensive care unit: Common causes of increased levels and interpretation
    • Fromm R. E. Cardiac troponins in the intensive care unit: common causes of increased levels and interpretation. Crit Care Med: 2007; 35 584 588
    • (2007) Crit Care Med , vol.35 , pp. 584-588
    • Fromm, R.E.1
  • 51
    • 33845980607 scopus 로고    scopus 로고
    • C-reactive protein: A nontraditional serum marker of cardiovascular risk
    • DOI 10.1016/j.carpath.2006.04.006, PII S1054880706000718
    • De Ferranti S. D., Rifai N. C-reactive protein: a nontraditional serum marker of cardiovascular risk. Cardiovasc Pathol: 2007; 16 14 21 (Pubitemid 46049026)
    • (2007) Cardiovascular Pathology , vol.16 , Issue.1 , pp. 14-21
    • De Ferranti, S.D.1    Rifai, N.2
  • 53
    • 12144249151 scopus 로고    scopus 로고
    • Effect of C-reactive protein on vascular cells: Evidence for a proinflammatory, proatherogenic role
    • DOI 10.1097/00041552-200501000-00006
    • Venugopal S. K., Devaraj S., Jialal I. Effect of C-reactive protein on vascular cells: evidence for a proinfl ammatory, proatherogenic role. Curr Opin Nephrol Hypertens: 2005; 14 33 37 (Pubitemid 40110697)
    • (2005) Current Opinion in Nephrology and Hypertension , vol.14 , Issue.1 , pp. 33-37
    • Venugopal, S.K.1    Devaraj, S.2    Jialal, I.3
  • 55
    • 79956276313 scopus 로고    scopus 로고
    • Relationship between inflammation biomarkers, antioxidant vitamins, and bone mineral density in patients with metabolic syndrome
    • Lee Y., Kim M., Choi K. et al. Relationship between inflammation biomarkers, antioxidant vitamins, and bone mineral density in patients with metabolic syndrome. Nutr Res Pract: 2011; 5 150 156
    • (2011) Nutr Res Pract , vol.5 , pp. 150-156
    • Lee, Y.1    Kim, M.2    Choi, K.3
  • 56
    • 0034500446 scopus 로고    scopus 로고
    • Free radicals, cytokines and nitric oxide in cardiac failure and myocardial infarction
    • DOI 10.1023/A:1026579422132
    • Das U. N. Free radicals, cytokines and nitric oxide in cardiac failure and myocardial infarction. Mol Cell Biochem: 2000; 215 145 152 (Pubitemid 32094953)
    • (2000) Molecular and Cellular Biochemistry , vol.215 , Issue.1-2 , pp. 145-152
    • Das, U.N.1
  • 57
    • 0035174972 scopus 로고    scopus 로고
    • Specificity, diversity, and convergence in VEGF and TNF-α signaling events leading to tissue factor upregulation via EGR-1 in endothelial cells
    • DOI 10.1096/fj.00-0247com
    • Mechtcheriakova D., Schabbauer G., Lucerna M. et al. Specificity, diversity, and convergence in VEGF and TNF-alpha signaling events leading to tissue factor up-regulation via EGR-1 in endothelial cells. FASEB J: 2001; 15 230 242 (Pubitemid 32061674)
    • (2001) FASEB Journal , vol.15 , Issue.1 , pp. 230-242
    • Mechtcheriakova, D.1    Schabbauer, G.2    Lucerna, M.3    Clauss, M.4    De Martin, R.5    Binder, B.R.6    Hofer, E.7
  • 59
    • 0001078987 scopus 로고    scopus 로고
    • Alterations of calcium-regulatory proteins in heart failure
    • DOI 10.1016/S0008-6363(97)00277-0, PII S0008636397002770
    • Hasenfuss G. Alterations of calcium-regulatory proteins in heart failure. Cardiovasc Res: 1998; 37 279 289 (Pubitemid 28165990)
    • (1998) Cardiovascular Research , vol.37 , Issue.2 , pp. 279-289
    • Hasenfuss, G.1
  • 60
    • 80155123422 scopus 로고    scopus 로고
    • Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis
    • Kain V., Kumar S., Sitasawad S. Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis. Cardiovasc Diabetol: 2011; 10 97 137
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 97-137
    • Kain, V.1    Kumar, S.2    Sitasawad, S.3
  • 61
    • 33747882881 scopus 로고    scopus 로고
    • DNA double-strand break repair and chromosome translocations
    • DOI 10.1016/j.dnarep.2006.05.029, PII S1568786406001698, Mechanisms of Chromosomal Translocations
    • Agarwal S., Tafel A. A., Kanaar R. DNA double-strand break repair and chromosome translocations. DNA Repair (Amst): 2006; 5 1075 1081 (Pubitemid 44291620)
    • (2006) DNA Repair , vol.5 , Issue.9-10 , pp. 1075-1081
    • Agarwal, S.1    Tafel, A.A.2    Kanaar, R.3
  • 62
    • 0029102911 scopus 로고
    • The single cell gel electrophoresis comet assay - A potential tool for detecting radiation-induced DNA damage in humans
    • 01
    • Tice R. R., Strauss GH S. The single cell gel electrophoresis comet assay - a potential tool for detecting radiation-induced DNA damage in humans. Stem CelLs: 1995; 13 01 207 214
    • (1995) Stem CelLs , vol.13 , pp. 207-214
    • Tice, R.R.1    Strauss, G.H.S.2
  • 64
    • 0035654245 scopus 로고    scopus 로고
    • Evaluation of the Genotoxicity of Zinc Oxide Eugenol-Based, Calcium Hydroxide-Based, and Epoxy Resin-Based Root Canal Sealers by Comet Assay
    • Huang T. H., Lee H., Kao C. T. Evaluation of the Genotoxicity of Zinc Oxide Eugenol-Based, Calcium Hydroxide-Based, and Epoxy Resin-Based Root Canal Sealers by Comet Assay. J Endownllcs: 2001; 27 744 748
    • (2001) J Endownllcs , vol.27 , pp. 744-748
    • Huang, T.H.1    Lee, H.2    Kao, C.T.3
  • 65
    • 60349122749 scopus 로고    scopus 로고
    • DNA damaging potential of zinc oxide nanoparticles in human epidermal cells
    • Sharma V., Shukla R. K., Saxena N. et al. DNA damaging potential of zinc oxide nanoparticles in human epidermal cells. Toxicol Lett: 2009; 185 211 218
    • (2009) Toxicol Lett , vol.185 , pp. 211-218
    • Sharma, V.1    Shukla, R.K.2    Saxena, N.3
  • 66
    • 79951813476 scopus 로고    scopus 로고
    • Effects of nano-scale TiO2, ZnO and their bulk counterparts on zebrafish: Acute toxicity, oxidative stress and oxidative damage
    • Xiong D., Fang T., Yu L. et al. Effects of nano-scale TiO2, ZnO and their bulk counterparts on zebrafish: acute toxicity, oxidative stress and oxidative damage. Sci Total Environ: 2011; 409 1444 1452
    • (2011) Sci Total Environ , vol.409 , pp. 1444-1452
    • Xiong, D.1    Fang, T.2    Yu, L.3
  • 68
    • 18144452679 scopus 로고    scopus 로고
    • Oxy radicals, lipid peroxidation and DNA damage
    • DOI 10.1016/S0300-483X(02)00448-1, PII S0300483X02004481
    • Marnett L. J. Oxy radicals, lipid peroxidation and DNA damage. Toxicol: 2002; 182 219 222 (Pubitemid 36015702)
    • (2002) Toxicology , vol.181-182 , pp. 219-222
    • Marnett, L.J.1
  • 70
    • 0029008917 scopus 로고
    • Inhibitory effects of vitamin e and ellagic acid on 8-hydroxy- deoxyguanosine formation in liver nuclear DNA of rats treated with 2- nitropropane
    • Takagi A., Sai K., Umemura T. et al. Inhibitory effects of vitamin E and ellagic acid on 8-hydroxy- deoxyguanosine formation in liver nuclear DNA of rats treated with 2- nitropropane. Cancer Lett: 1995; 91 139 144
    • (1995) Cancer Lett , vol.91 , pp. 139-144
    • Takagi, A.1    Sai, K.2    Umemura, T.3
  • 71
    • 0031428577 scopus 로고    scopus 로고
    • 8dG in the liver of guinea-pigs supplemented with graded dietary doses of ascorbic acid and α-tocopherol
    • DOI 10.1093/carcin/18.12.2373
    • Cadenas S., Barjal G., Poulsen H. E. et al. Oxidative DNA damage estimated by oxo8dG in the liver of guinea-pigs supplemented with graded dietary doses of ascorbic acid and a-tocopherol. Carcinogenesis: 1997; 18 2373 2377 (Pubitemid 28134652)
    • (1997) Carcinogenesis , vol.18 , Issue.12 , pp. 2373-2377
    • Cadenas, S.1    Barja, G.2    Poulsen, H.E.3    Loft, S.4
  • 72
    • 0037404268 scopus 로고    scopus 로고
    • Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and α-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: A study of their individual and synergistic actions
    • Burillo S. L., Tan D. X., Mayo J. C. et al. Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and α-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions. J Pineal Res: 2003; 34 269 277 (Pubitemid 36469773)
    • (2003) Journal of Pineal Research , vol.34 , Issue.4 , pp. 269-277
    • Lopez-Burillo, S.1    Tan, D.-X.2    Mayo, J.C.3    Sainz, R.M.4    Manchester, L.C.5    Reiter, R.J.6
  • 73
    • 0032938438 scopus 로고    scopus 로고
    • Dose dependent protection by lipoic acid against cisplatin-induced ototoxicity in rats: Antioxidant defense system
    • DOI 10.1093/toxsci/47.2.195
    • Rybak L. P., Hussain K., Whiteworth C. et al. Dose dependent protection by α-lipoic acid against cisplatin-induced ototoxicity in rats. Antioxidant defense system. Toxicol Sci: 1999; 47 195 202 (Pubitemid 29214827)
    • (1999) Toxicological Sciences , vol.47 , Issue.2 , pp. 195-202
    • Rybak, L.P.1    Husain, K.2    Whitworth, C.3    Somani, S.M.4
  • 74
    • 79958062794 scopus 로고    scopus 로고
    • Hepatoprotective effect of vitamin E/selenium against malathion induced injuries on the antioxidant status and apoptosis realted gene expression in rats
    • Aboul-Soud MA M., Othman A. M., El-Desoky G. E. et al. Hepatoprotective effect of vitamin E/selenium against malathion induced injuries on the antioxidant status and apoptosis realted gene expression in rats. J Toxicol Sci: 2011; 36 285 296
    • (2011) J Toxicol Sci , vol.36 , pp. 285-296
    • Aboul-Soud, M.A.M.1    Othman, A.M.2    El-Desoky, G.E.3


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