Zinc oxide nanoparticles cause nephrotoxicity and kidney metabolism alterations in rats

Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering

Volumn 47, Issue 4, 2012, Pages 577-588

  Yan, Guangyan ^a   Huang, Yina ^a   Bu, Qian ^a   Lv, Lei ^a   Deng, Pengchi ^b   Zhou, Jiaqing ^a   Wang, Yanli ^c   Yang, Yanzhu ^a   Liu, Qiangqiang ^a   Cen, Xiaobo ^a   Zhao, Yinglan ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c Sichuan Women and Children's Hospital   (China)

Author keywords

Metabonomic; Nanoparticle; Toxicity; Zinc oxide

Indexed keywords

BIOCHEMICAL COMPOSITION; BLOOD UREA; CLINICAL BIOCHEMISTRY; ENERGY METABOLISM; EPITHELIAL CELLS; H NMR SPECTRA; HAEMATOCRIT; HEMOGLOBIN CONCENTRATION; HISTOPATHOLOGICAL EXAMINATIONS; KETOGLUTARATE; METABOLIC PROFILES; METABONOMICS; NEPHROTOXICITY; NUCLEAR MAGNETIC RESONANCE TECHNIQUES; PARTIAL LEAST SQUARES-DISCRIMINANT ANALYSIS; PHOSPHOCHOLINE; POTENTIAL HAZARDS; RAT KIDNEYS; ZINC OXIDE NANOPARTICLES; ZNO;

AMINO ACIDS; BIOCHEMISTRY; BODY FLUIDS; CELL DEATH; CELL MEMBRANES; DISCRIMINANT ANALYSIS; GLUCOSE; HEMOGLOBIN; METABOLISM; NANOPARTICLES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATTERN RECOGNITION; RATS; TOXICITY;

ZINC OXIDE;

2 OXOGLUTARIC ACID; 3 HYDROXYBUTYRIC ACID; 4 HYDROXYPHENYLACETIC ACID; ACETIC ACID; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CITRIC ACID; CREATINE; CREATINE KINASE; CREATININE; GLUCOSE; HEMOGLOBIN; HIPPURIC ACID; LACTATE DEHYDROGENASE; LACTIC ACID; NANOPARTICLE; PHOSPHORYLCHOLINE; SUCCINIC ACID; TAURINE; TRIMETHYLAMINE OXIDE; ZINC OXIDE;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANOREXIA; ANURIA; ARTICLE; BIOCHEMICAL COMPOSITION; BLOOD SAMPLING; CELL MEMBRANE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIARRHEA; DROWSINESS; ENERGY METABOLISM; GLUCOSE METABOLISM; HEMATOCRIT; HISTOPATHOLOGY; KIDNEY METABOLISM; KIDNEY NECROSIS; KIDNEY TUBULE EXCRETION; MALE; MEAN CORPUSCULAR HEMOGLOBIN; MITOCHONDRION; NEPHROTOXICITY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SCANNING ELECTRON MICROSCOPY; UREA NITROGEN BLOOD LEVEL; URINALYSIS;

ANIMALS; KIDNEY; MAGNETIC RESONANCE SPECTROSCOPY; METAL NANOPARTICLES; MICROSCOPY, ELECTRON, SCANNING; RATS; ZINC OXIDE;

MAMMALIA; RATTUS;

EID: 84859706392     PISSN: 10934529     EISSN: 15324117     Source Type: Journal    
DOI: 10.1080/10934529.2012.650576     Document Type: Article

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