Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation

Environmental Health Perspectives

Volumn 117, Issue 2, 2009, Pages 241-247

  Lu, Senlin ^a,b   Duffin, Rodger ^a   Poland, Craig ^a   Daly, Paul ^a   Murphy, Fiona ^a   Drost, Ellen ^a   MacNee, William ^a   Stone, Vicki ^c   Donaldson, Ken ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b SHANGHAI UNIVERSITY   (China)

^c EDINBURGH NAPIER UNIVERSITY   (United Kingdom)

Author keywords

Electron paramagnetic resonance; EPR; Inflammation; Lungs; Nanoparticles; Oxidative stress; ROS

Indexed keywords

ALUMINA 2; ALUMINA 3; ALUMINA 4; FREE RADICAL; MAGNESIUM OXIDE; METAL OXIDE; METAL OXIDE NANOPARTICLE; NANOPARTICLE; NICKEL MONOXIDE; SILICON DIOXIDE; TITANIUM DIOXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; CONTROLLED STUDY; CYTOTOXICITY; ELECTRON SPIN RESONANCE; ENVIRONMENTAL EXPOSURE; EPITHELIUM CELL; FEMALE; HEALTH HAZARD; HEMOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ALVEOLUS EPITHELIUM; MEMBRANE DAMAGE; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PREDICTION; PRIORITY JOURNAL; RAT; RISK ASSESSMENT; TOXICITY TESTING;

ALUMINUM OXIDE; CELL LINE; ERYTHROCYTES; HEMOLYSIS; HUMANS; METAL NANOPARTICLES; NICKEL; OXIDES; PNEUMONIA;

ANIMALIA; RATTUS;

EID: 60749122689     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.11811     Document Type: Article

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