α-Lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 10, 2007, Pages 4077-4082

  Zhang, Wei Jian ^a   Wei, Hao ^a   Hagen, Tory ^a   Frei, Balz ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

Endothelial activation; Inflammation; Monocytes; NF B; Sepsis

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTIOXIDANT; CELL ADHESION MOLECULE; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; THIOCTIC ACID; THIOL DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; WORTMANNIN; ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL ADHESION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENDOTHELIUM CELL; ENDOTOXEMIA; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; SEPSIS; SIGNAL TRANSDUCTION; SURVIVAL; UPREGULATION; ANIMAL; C57BL MOUSE; MALE; METABOLISM; TUMOR CELL LINE;

ANIMALIA; MUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; CELL LINE, TUMOR; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C57BL; PROTO-ONCOGENE PROTEINS C-AKT; SEPSIS; SIGNAL TRANSDUCTION; THIOCTIC ACID;

EID: 34247220265     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0700305104     Document Type: Article

References (43)

1. Guha M, Mackman N (2001) Cell Signalling 13:85-94.
2. Aird WC (2003) Blood 101:3765-3777.
3. Parrillo JE (1993) N Engl J Med 328:1471-1477.
4. Natanson C, Hoffman WD, Suffredini AF, Eichacker PQ, Danner RL (1994) Ann Intern Med 120:771-783.
5. Christman JW, Holden EP, Blackwell TS (1995) Crit Care Med 23:955-963.
6. Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T (1995) FASEB J 9:899-909.
7. Karin M, Liu Z, Zandi E (1997) Curr Opin Cell Biol 9:240-246.
8. Liu H, Colavitti R, Rovira II, Finkel T (2005) Circ Res 97:967-974.
9. Marui N, Offermann MK, Swerlick R, Kunsch C, Rosen CA, Ahmad M, Alexander RW, Medford RM (1993) J Clin Invest 92:1866-1874.
10. Weber C, Erl W, Pietsch A, Strobel M, Ziegler-Heitbrock HW, Weber PC (1994) Arterioscler Thromb 14:1665-1673.
11. Zhang WJ, Frei B (2001) FASEB J 15:2423-2432.
12. Blackwell TS, Blackwell TR, Holden EP, Christman BW, Christman JW (1996) J Immunol 157:1630-1637.
13. Liu SF, Ye X, Malik AB (1999) Circulation 100:1330-1337.
14. Victor VM, Rocha M, De la Fuente M (2003) Int Immunopharmacol 3:97-106.
15. Guha M, Mackman N (2002) J Biol Chem 277:32124-32132.
16. Schabbauer G, Tencati M, Pedersen B, Pawlinski R, Mackman N (2004) Arterioscler Thromb Vasc Biol 24:1963-1969.
17. Williams DL, Li C, Ha T, Ozment-Skelton T, Kalbfleisch JH, Preiszner J, Brooks L, Breuel K, Schweitzer JB (2004) J Immunol 172:449-456.
18. Kim I, Oh JL, Ryu YS, So JN, Sessa WC, Walsh K, Koh GY (2002) FASEB J 16:126-128.
19. Bommhardt U, Chang KC, Swanson PE, Wagner TH, Tinsley KW, Karl IE, Hotchkiss RS (2004) J Immunol 172:7583-7591.
20. Rajaram MV, Ganesan LP, Parsa KV, Butchar JP, Gunn JS, Tridandapani S (2006) J Immunol 177:6317-6324.
21. Fukao T, Koyasu S (2003) Trends Immunol 24:358-363.
22. Martin MK, Rehani RS, Jope SM, Michalek (2005) Nat Immunol 6:777-784.
23. Packer L, Witt EH, Tritschler HJ (1995) Free Radical Biol Med 19:227-250.
24. Smith AR, Shenvi SV, Widlansky M, Suh JH, Hagen TM (2004) Curr Med Chem 11:1135-1146.
25. Biewenga GP, Haenen GR, Bast A (1997) Gen Pharmacol 29:315-331.
26. Ziegler D (2004) Treat Endocrinol 3:173-189.
27. Melhem A, Stern M, Shibolet O, Israeli E, Ackerman Z, Pappo O, Hemed N, Rowe M, Ohana H, Zabrecky G, et al. (2005) J Clin Gastroenterol 39:737-742.
28. Sola S, Mir MQ, Cheema FA, Khan-Merchant N, Menon RG, Parthasarathy S, Khan BV (2005) Circulation 111:343-348.
29. Cho YS, Lee J, Lee TH, Lee EY, Lee KU, Park JY, Moon HB (2004) J Allergy Clin Immunol 114:429-435.
30. Jesudason EP, Masilamoni JG, Jesudoss KS, Jayakumar R (2005) Mol Cell Biochem 270:29-37.
31. Matsuda N, Hayashi Y, Takahashi Y, Hattori Y (2006) J Pharmacol Exp Ther 319:1348-1354.
32. Awad SS (2003) Am J Surg 186:23S-30S.
33. Liu SF, Malik AB (2006) Am J Physiol 290:L622-L645.
34. Bohrer H, Qiu F, Zimmermann T, Zhang Y, Jllmer T, Mantel D, Bottiger BW, Stern DM, Waldherr R, Saeger HD, et al. (1997) J Clin Invest 100:972-985.
35. Arnalich F, Garcia-Palomero E, Lopez J, Jimenez M, Madero R, Renart J, Vazquez JJ, Montiel C (2000) Infect Immun 68:1942-1945.
36. Ong E, Gao XP, Predescu D, Broman M, Malik AB (2005) Am J Physiol 289:L1094-L1103.
37. Rudich A, Tirosh A, Potashnik R, Khamaisi M, Bashan N (1999) Diabetologia 42:949-957.
38. Zhang L, Xing GQ, Barker JL, Chang Y, Maric D, Ma W, Li BS, Rubinow DR (2001) Neurosci Lett 312:125-128.
39. Muller C, Dunschede F, Koch E, Vollmar AM, Kiemer AK (2003) Am J Physiol 285:G769-G778.
40. Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB (1999) Nature 401:82-85.
41. Thomas KW, Monick MM, Stabler JM, Yarovinsky T, Carter AB, Hunninghake GW (2002) J Biol Chem 277:492-501.
42. Madrid LV, Mayo MW, Reuther JY, Baldwin AS, Jr (2001) J Biol Chem 276:18934-18940.
43. Mervaala E, Finckenberg P, Lapatto R, Muller DN, Park JK, Dechend R, Ganten D, Vapaatalo H, Luft FC (2003) Kidney Int 64:501-508.