Methylenetetrahydrofolate reductase: Biochemical characterization and medical significance

Current Pharmaceutical Design

Volumn 19, Issue 14, 2013, Pages 2574-2593

  Trimmer, Elizabeth E ^a  

^a GRINNELL COLLEGE   (United States)

Author keywords

C677T polymorphism; FAD; Flavin; Folate; Homocysteine; Methylenetetrahydrofolate; Methyltetrahydrofolate; MTHFR

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); BACTERIAL ENZYME; DIHYDROFOLIC ACID; FLAVOPROTEIN; FOLIC ACID; HYDROGEN; MENADIONE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; TETRAHYDROFOLIC ACID;

ACUTE LYMPHOBLASTIC LEUKEMIA; ALLOSTERISM; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARABIDOPSIS; ARABIDOPSIS THALIANA; ASPERGILLUS NIDULANS; CARDIOVASCULAR DISEASE; CHEMICAL ANALYSIS; CLOSTRIDIUM; CLOSTRIDIUM FORMICOACETIUM; COLORECTAL CANCER; CRYSTAL STRUCTURE; DEMENTIA; ENZYME ACTIVITY; ENZYME PURIFICATION; ESCHERICHIA COLI; FOLATE METABOLISM; FUSARIUM GRAMINEARUM; GENETIC RISK; HUMAN; HYPERHOMOCYSTEINEMIA; INSECT CELL; KINETICS; LEISHMANIA; MENTAL DISEASE; NEURAL TUBE DEFECT; NONHUMAN; PEPTOSTREPTOCOCCUS; PEPTOSTREPTOCOCCUS PRODUCTUS; PHENOTYPE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVIEW; SACCHAROMYCES CEREVISIAE; SCANNING TRANSMISSION ELECTRON MICROSCOPY; SCHIZOSACCHAROMYCES POMBE; SINGLE NUCLEOTIDE POLYMORPHISM; STEADY STATE; STOMACH CANCER; SWINE; THERMUS THERMOPHILUS; YEAST;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; ANIMALS; ARABIDOPSIS; CARDIOVASCULAR DISEASES; CATALYSIS; ESCHERICHIA COLI; HOMOCYSTEINE; HUMANS; HYPERHOMOCYSTEINEMIA; LEISHMANIA MAJOR; MENTAL DISORDERS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEOPLASMS; NEURAL TUBE DEFECTS; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ALIGNMENT; TETRAHYDROFOLATES;

EID: 84877816906     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612811319140008     Document Type: Review

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