메뉴 건너뛰기




Volumn 95, Issue 8, 1997, Pages 2032-2036

Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease

Author keywords

coronary disease; genetics; myocardial infarction; risk factors

Indexed keywords

METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE;

EID: 0030897112     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.95.8.2032     Document Type: Article
Times cited : (313)

References (32)
  • 1
    • 0029939676 scopus 로고    scopus 로고
    • Homocysteine and vascular disease
    • McCully KS. Homocysteine and vascular disease. Nat Med. 1996;2:386-389.
    • (1996) Nat Med. , vol.2 , pp. 386-389
    • McCully, K.S.1
  • 5
    • 0017197285 scopus 로고
    • Homocystine-induced arteriosclerosis: The role of endothelial cell injury and platelet response in its genesis
    • Harker LA, Ross R, Slichter SJ, Scott CR. Homocystine-induced arteriosclerosis: the role of endothelial cell injury and platelet response in its genesis. J Clin Invest. 1976;58:731-741.
    • (1976) J Clin Invest. , vol.58 , pp. 731-741
    • Harker, L.A.1    Ross, R.2    Slichter, S.J.3    Scott, C.R.4
  • 12
    • 0026034240 scopus 로고
    • Thermolabile methylenetetrahydrofolate reductase: An inherited risk factor for coronary artery disease
    • Kang SS, Wong PW, Susmano A, Sora J, Norusis M, Ruggie N. Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease. Am J Hum Genet. 1991;48:536-545.
    • (1991) Am J Hum Genet. , vol.48 , pp. 536-545
    • Kang, S.S.1    Wong, P.W.2    Susmano, A.3    Sora, J.4    Norusis, M.5    Ruggie, N.6
  • 14
    • 0023628783 scopus 로고
    • Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection
    • Araki A, Sako Y. Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection. J Chromatogr. 1987;422:43-52.
    • (1987) J Chromatogr. , vol.422 , pp. 43-52
    • Araki, A.1    Sako, Y.2
  • 15
    • 0018858624 scopus 로고
    • Homocysteine-induced endothelial cell injury in vitro: A model for the study of vascular injury
    • Wall RT, Harlan JM, Harker LA, Striker GE. Homocysteine-induced endothelial cell injury in vitro: a model for the study of vascular injury. Thromb Res. 1980;18:113-121.
    • (1980) Thromb Res. , vol.18 , pp. 113-121
    • Wall, R.T.1    Harlan, J.M.2    Harker, L.A.3    Striker, G.E.4
  • 16
    • 0022552919 scopus 로고
    • Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine
    • Starkebaum G, Harlan JM. Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. J Clin Invest. 1986;77:1370-1376.
    • (1986) J Clin Invest. , vol.77 , pp. 1370-1376
    • Starkebaum, G.1    Harlan, J.M.2
  • 17
    • 0025806820 scopus 로고
    • Homocysteine thiolactone disposal by human arterial endothelial cells and serum in vitro
    • Dudman NP, Hicks C, Lynch JF, Wilcken DE, Wang J. Homocysteine thiolactone disposal by human arterial endothelial cells and serum in vitro. Arterioscler Thromb. 1991;11:663-670.
    • (1991) Arterioscler Thromb. , vol.11 , pp. 663-670
    • Dudman, N.P.1    Hicks, C.2    Lynch, J.F.3    Wilcken, D.E.4    Wang, J.5
  • 20
    • 0022472013 scopus 로고
    • Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator
    • Rodgers GM, Kane WH. Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator. J Clin Invest. 1986;77:1909-1916.
    • (1986) J Clin Invest. , vol.77 , pp. 1909-1916
    • Rodgers, G.M.1    Kane, W.H.2
  • 21
    • 0026345948 scopus 로고
    • Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine
    • Lentz SR, Sadler JE. Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine. J Clin Invest. 1991;88:1906-1914.
    • (1991) J Clin Invest. , vol.88 , pp. 1906-1914
    • Lentz, S.R.1    Sadler, J.E.2
  • 22
    • 0025190042 scopus 로고
    • Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells
    • Rodgers GM, Conn MT. Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells. Blood. 1990;75:895-901.
    • (1990) Blood , vol.75 , pp. 895-901
    • Rodgers, G.M.1    Conn, M.T.2
  • 23
    • 0027288252 scopus 로고
    • Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor
    • Hajjar KA. Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor. J Clin Invest. 1993;91:2873-2879.
    • (1993) J Clin Invest. , vol.91 , pp. 2873-2879
    • Hajjar, K.A.1
  • 24
    • 0027319970 scopus 로고
    • Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells
    • Nishinaga M, Ozawa T, Shimada K. Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells. J Clin Invest. 1993;92:1381-1386.
    • (1993) J Clin Invest. , vol.92 , pp. 1381-1386
    • Nishinaga, M.1    Ozawa, T.2    Shimada, K.3
  • 29
    • 0027198477 scopus 로고
    • Disordered methionine/homocysteine metabolism in premature vascular disease: Its occurrence, cofactor therapy, and enzymology
    • Dudman NP, Wilcken DE, Wang J, Lynch JF, Macey D, Lundberg P. Disordered methionine/homocysteine metabolism in premature vascular disease: its occurrence, cofactor therapy, and enzymology. Arterioscler Thromb. 1993;13:1253-1260.
    • (1993) Arterioscler Thromb. , vol.13 , pp. 1253-1260
    • Dudman, N.P.1    Wilcken, D.E.2    Wang, J.3    Lynch, J.F.4    Macey, D.5    Lundberg, P.6
  • 31
    • 0029069203 scopus 로고
    • Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations
    • Naurath HJ, Joosten E, Riezler R, Stabler SP, Allen RH, Lindenbaum J. Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations. Lancet. 1995; 346:85-89.
    • (1995) Lancet , vol.346 , pp. 85-89
    • Naurath, H.J.1    Joosten, E.2    Riezler, R.3    Stabler, S.P.4    Allen, R.H.5    Lindenbaum, J.6
  • 32
    • 0030057401 scopus 로고    scopus 로고
    • Distribution in healthy and coronary populations of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation
    • Wilcken DEL, Wang XL, Sim AS, McCredie RM. Distribution in healthy and coronary populations of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation. Arterioscler Thromb Vasc Biol. 1996;16:878-882.
    • (1996) Arterioscler Thromb Vasc Biol. , vol.16 , pp. 878-882
    • Wilcken, D.E.L.1    Wang, X.L.2    Sim, A.S.3    McCredie, R.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.