Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8: Structural basis for the flavin affinity

Proteins: Structure, Function and Genetics

Volumn 70, Issue 3, 2008, Pages 718-730

  Kim, Seong Hoon ^a   Hisano, Tamao ^a   Iwasaki, Wakana ^a   Ebihara, Akio ^a   Miki, Kunio ^a,b  

^a RIKEN Harima Institute ^*  (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Diffusible flavin; Two component monooxygenase

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 4 HYDROXYPHENYLACETATE 3 MONOOXYGENASE; 4 HYDROXYPHENYLACETIC ACID; ADENOSINE PHOSPHATE; BACTERIAL ENZYME; DIMER; FLAVIN REDUCTASE; FLAVINE ADENINE NUCLEOTIDE; HYDROXYL GROUP; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE; OXYGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TERNARY COMPLEX FACTOR; UNCLASSIFIED DRUG; WATER;

ARTICLE; BACILLUS; BACILLUS THERMOGLUCOSIDASIUS; BINDING AFFINITY; CATALYSIS; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DIPOLE; DISSOCIATION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; REACTION ANALYSIS; THERMUS THERMOPHILUS;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; FLAVIN-ADENINE DINUCLEOTIDE; FMN REDUCTASE; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP; THERMUS THERMOPHILUS;

GEOBACILLUS THERMOGLUCOSIDASIUS; THERMUS THERMOPHILUS;

EID: 38549124488     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21534     Document Type: Article

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