-
1
-
-
0029049553
-
A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
-
Frosst, P. et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nature Genet. 10, 111-113 (1995).
-
(1995)
Nature Genet.
, vol.10
, pp. 111-113
-
-
Frosst, P.1
-
2
-
-
0029655724
-
Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease
-
Kluijtmans, LA. et al. Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am. J. Hum. Genet. 58, 35-41 (1996).
-
(1996)
Am. J. Hum. Genet.
, vol.58
, pp. 35-41
-
-
Kluijtmans, L.A.1
-
3
-
-
0030897112
-
Genetic polymorphism of 5, 10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease
-
Morita, H. et al. Genetic polymorphism of 5, 10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation 95, 2032-2036(1997).
-
(1997)
Circulation
, vol.95
, pp. 2032-2036
-
-
Morita, H.1
-
4
-
-
0030057401
-
Distribution in healthy and coronary populations of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation
-
Wilcken, D.E., Wang, X.L, Sim, A.S. & McCredie, R.M. Distribution in healthy and coronary populations of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation. Arteroider. Thromb. Vase. Biol. 16, 878-882 (1996).
-
(1996)
Arteroider. Thromb. Vase. Biol.
, vol.16
, pp. 878-882
-
-
Wilcken, D.E.1
Wang, X.L.2
Sim, A.S.3
McCredie, R.M.4
-
5
-
-
0029806746
-
Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians
-
Ma, J. et al. Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation 94, 2410-2416(1996).
-
(1996)
Circulation
, vol.94
, pp. 2410-2416
-
-
Ma, J.1
-
6
-
-
0030027668
-
Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
-
. 6. Jacques, P.F. et aL Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 93, 7-9 (1996).
-
(1996)
Circulation
, vol.93
, pp. 7-9
-
-
Jacques, P.F.1
-
7
-
-
0029738540
-
The common "thermolabile" variant of methylenetetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia
-
Harmon, D.L. et al. The common "thermolabile" variant of methylenetetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia. Q. J. Med. 89, 515-577(1996).
-
(1996)
Q. J. Med.
, vol.89
, pp. 515-577
-
-
Harmon, D.L.1
-
9
-
-
0031958860
-
Homocysteine and cardiovascular disease
-
Refsum, H., Ueland, P.M., Nygard, O. & Vollset, S. Homocysteine and cardiovascular disease. Annu. Rev. Med. 49, 31-62 (1998).
-
(1998)
Annu. Rev. Med.
, vol.49
, pp. 31-62
-
-
Refsum, H.1
Ueland, P.M.2
Nygard, O.3
Vollset, S.4
-
10
-
-
0031066138
-
Is the common 677C-VT mutation in the methylenetetrahydrofolate reductase gene a risk factor for neural tube defects? a meta-analysis
-
van der Put, N.M.J., Eskes, T.K.A.B. & Blom, H.J. Is the common 677C-VT mutation in the methylenetetrahydrofolate reductase gene a risk factor for neural tube defects? A meta-analysis. Q. J. Med. 90, 111-115 (1997).
-
(1997)
Q. J. Med.
, vol.90
, pp. 111-115
-
-
Van Der Put, N.M.J.1
Eskes, T.K.A.B.2
Blom, H.J.3
-
11
-
-
0029066299
-
A quantitative assessment of plasma homocysteine as a risk factor for vascular disease
-
Boushey, C.J., Beresford. S.A.A. Omenn, G.S. & Motulsky, A.G. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. JAMA 274, 1049-1057(1995).
-
(1995)
JAMA
, vol.274
, pp. 1049-1057
-
-
Boushey, C.J.1
Beresford, S.A.A.2
Omenn, G.S.3
Motulsky, A.G.4
-
13
-
-
0028304102
-
Human methylenetetrahydrofolate reductase: Isolation of cDNA, mapping and mutation identification
-
Goyette, P. et al. Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification. Nature Genet. 7, 195-200 (1994).
-
(1994)
Nature Genet.
, vol.7
, pp. 195-200
-
-
Goyette, P.1
-
14
-
-
0026030641
-
Database of homology-derived protein structures and the structural meaning of sequence alignment
-
Sander, C. & Schneider, R. Database of homology-derived protein structures and the structural meaning of sequence alignment. Proteins 9, 56-68 (1991).
-
(1991)
Proteins
, vol.9
, pp. 56-68
-
-
Sander, C.1
Schneider, R.2
-
15
-
-
0029847109
-
Severe and mild mutations in cis for the methylenetetrahydofolate reductase (MTHFR) gene, and description of five novel mutations in MTHFR
-
Goyette, P., Christensen, B., Rosenblatt, D.S. & Rozen, R. Severe and mild mutations in cis for the methylenetetrahydofolate reductase (MTHFR) gene, and description of five novel mutations in MTHFR. Am. J. Hum. Genet. 59, 1268-1275 (1996).
-
(1996)
Am. J. Hum. Genet.
, vol.59
, pp. 1268-1275
-
-
Goyette, P.1
Christensen, B.2
Rosenblatt, D.S.3
Rozen, R.4
-
16
-
-
0028905178
-
Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency
-
Goyette, P., Fresst, P., Rosenblatt, D.S. & Rozen, R. Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency. Am. J. Hum. Genet. 56, 1052-1059 (1995).
-
(1995)
Am. J. Hum. Genet.
, vol.56
, pp. 1052-1059
-
-
Goyette, P.1
Fresst, P.2
Rosenblatt, D.S.3
Rozen, R.4
-
17
-
-
0024962365
-
Refined structure of spinach glycolate oxidase at 2 a resolution
-
Lindqvist, Y. Refined structure of spinach glycolate oxidase at 2 A resolution. J. Mol. Biol. 209, 151-166 (1989).
-
(1989)
J. Mol. Biol.
, vol.209
, pp. 151-166
-
-
Lindqvist, Y.1
-
18
-
-
0025278264
-
Molecular structure of flavocytochrome b2 at 2.4 a resolution
-
Xia, Z.X. & Mathews, F.S. Molecular structure of flavocytochrome b2 at 2.4 A resolution./ Mol. Biol. 212.837-863 (1990).
-
(1990)
Mol. Biol.
, vol.212
, pp. 837-863
-
-
Xia, Z.X.1
Mathews, F.S.2
-
19
-
-
0028774535
-
Old yellow enzyme at 2 a resolution: Overall structure, ligand binding, and comparison with related flavoproteins
-
Fox, K.M. & Karplus, P.A. Old yellow enzyme at 2 A resolution: overall structure, ligand binding, and comparison with related flavoproteins. Structure 2, 1089-1105(1994).
-
(1994)
Structure
, vol.2
, pp. 1089-1105
-
-
Fox, K.M.1
Karplus, P.A.2
-
20
-
-
0022982155
-
Three-dimensional structure of the iron-sulfur flavoprotein trimethylamine dehydrogenase at 2.4 a resolution
-
Lim, L.W. Three-dimensional structure of the iron-sulfur flavoprotein trimethylamine dehydrogenase at 2.4 A resolution. J. Biol. Chem. 261, 15140-15146(1986).
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 15140-15146
-
-
Lim, L.W.1
-
21
-
-
0031568812
-
The crystal structure of the flavin containing enzyme dihydroorotate dehydrogenase a from
-
Rowland, P., Nielsen, F.S., Jensen, K.F. & Larsen, S. The crystal structure of the flavin containing enzyme dihydroorotate dehydrogenase A from Lactococcus /art. Structure 5. 239-252 (1997).
-
(1997)
Lactococcus /Art. Structure
, vol.5
, pp. 239-252
-
-
Rowland, P.1
Nielsen, F.S.2
Jensen, K.F.3
Larsen, S.4
-
22
-
-
0000282187
-
Stereochemistry and mechanism of hydrogen transfer between NADPH and methylenetetrahydrofolate in the reaction catalyzed by methylenetetrahydrofolate reductase from pig liver
-
Sumner, J.S. & Matthews, R.G. Stereochemistry and mechanism of hydrogen transfer between NADPH and methylenetetrahydrofolate in the reaction catalyzed by methylenetetrahydrofolate reductase from pig liver. J. Am. Chem. Soc. 114, 6949-6956 (1992).
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 6949-6956
-
-
Sumner, J.S.1
Matthews, R.G.2
-
23
-
-
0025265852
-
Rubredoxin reductase of Pseudomonas oleovorans. Structural relationship to other flavoprotein oxidoreductases based on one NAD and two FAD fingerprints
-
Eggink, G., Engel, H., Vriend, G., Terpstra, P. & Witholt, B. Rubredoxin reductase of Pseudomonas oleovorans. Structural relationship to other flavoprotein oxidoreductases based on one NAD and two FAD fingerprints. J. Mol. Biol. 212, 135-142(1990).
-
(1990)
J. Mol. Biol
, vol.212
, pp. 135-142
-
-
Eggink, G.1
Engel, H.2
Vriend, G.3
Terpstra, P.4
Witholt, B.5
-
24
-
-
0032945180
-
Purification and properties of NADH-dependent 5, 10-methylenetetrahydrofolate reductase from
-
Sheppard, CA., Trimmer, E.E. & Matthews, R.G. Purification and properties of NADH-dependent 5, 10-methylenetetrahydrofolate reductase from Escherichia coli.J. Bacteriol. 181.718-725 (1999).
-
(1999)
Escherichia Coli.J. Bacteriol.
, vol.181
, pp. 718-725
-
-
Sheppard, C.A.1
Trimmer, E.E.2
Matthews, R.G.3
-
25
-
-
0026034240
-
Thermolabile methylenetetrahydrofolate reductase: An inherited risk factor for coronary artery disease
-
Kang, S.-S. etal. Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease. Am. J. Hum. Genet. 48, 536-545 (1991).
-
(1991)
Am. J. Hum. Genet
, vol.48
, pp. 536-545
-
-
Kang, S.-S.1
-
26
-
-
0032575295
-
Thermodynamic stability of arachaeal histones
-
U, W.-T. etal. Thermodynamic stability of arachaeal histones. Biochemistry 37, 10563-10572(1998).
-
(1998)
Biochemistry
, vol.37
, pp. 10563-10572
-
-
W-T, U.1
-
27
-
-
0019323528
-
Interactions of pig liver methylenetetrahydrofolate reductase with methylenetetrahydropteroylpolyglutamate substrates and with dihydropteroylpolyglutamate inhibitors
-
Matthews, R.G. & Baugh, C.M. Interactions of pig liver methylenetetrahydrofolate reductase with methylenetetrahydropteroylpolyglutamate substrates and with dihydropteroylpolyglutamate inhibitors. Biochemistry 19, 2040-2045 (1980).
-
(1980)
Biochemistry
, vol.19
, pp. 2040-2045
-
-
Matthews, R.G.1
Baugh, C.M.2
-
28
-
-
0029109468
-
Protein-protein interactions: A review of protein dimer structures
-
Jones, S. & Thornton, J.M. Protein-protein interactions: a review of protein dimer structures. Prog. Biophys. Mol. Biol. 63, 31-65 (1995).
-
(1995)
Prog. Biophys. Mol. Biol.
, vol.63
, pp. 31-65
-
-
Jones, S.1
Thornton, J.M.2
-
29
-
-
0030997363
-
Hydrophobie patches on protein subunit interfaces: Characteristics and prediction
-
Lijnzaad, P. & Argos, P. Hydrophobie patches on protein subunit interfaces: characteristics and prediction. Proteins 28, 333-343 (1997).
-
(1997)
Proteins
, vol.28
, pp. 333-343
-
-
Lijnzaad, P.1
Argos, P.2
-
30
-
-
0030979178
-
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage
-
Blount, B.C. et al. Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage. Fron. Natl. Acad. Sci. USA 94, 3290-3295 (1997).
-
(1997)
Fron. Natl. Acad. Sci. USA
, vol.94
, pp. 3290-3295
-
-
Blount, B.C.1
-
31
-
-
0030476385
-
Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine metabolism and late-onset vascular disease
-
Deloughery, T.G. et al. Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine metabolism and late-onset vascular disease. Circulation 94.3074-3078 (1996).
-
(1996)
Circulation
, vol.94
, pp. 3074-3078
-
-
Deloughery, T.G.1
-
32
-
-
0031058883
-
Phase determination from multiwavelength anomalous diffraction experiments
-
Hendrickson, W.A. & Ogata, C.M. Phase determination from multiwavelength anomalous diffraction experiments. Methods fnzymo/276, 494-522 (1997).
-
(1997)
Methods Fnzymo
, vol.276
, pp. 494-522
-
-
Hendrickson, W.A.1
Ogata, C.M.2
-
33
-
-
0028103275
-
-
The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D 50, 760-763(1994).
-
(1994)
Acta Crystallogr. D
, vol.50
, pp. 760-763
-
-
-
36
-
-
0028172551
-
Protein hydration observed by X-ray diffraction. Solvation properties of penicillopepsin and neuraminidase crystal structures
-
Jiang, J.S. & Brunger, A.T. Protein hydration observed by X-ray diffraction. Solvation properties of penicillopepsin and neuraminidase crystal structures. J. Mol. Biol. 264, 100-115 (1994).
-
(1994)
J. Mol. Biol.
, vol.264
, pp. 100-115
-
-
Jiang, J.S.1
Brunger, A.T.2
-
38
-
-
0017667672
-
Methylenetetrahydrofolate reductase in cultured human cells. I. Growth and metabolic studies
-
Rosenblatt, D.S. & Erbe, R.W. Methylenetetrahydrofolate reductase in cultured human cells. I. Growth and metabolic studies. Pediatr. Res. 11, 1137-1141 (1977).
-
(1977)
Pediatr. Res.
, vol.11
, pp. 1137-1141
-
-
Rosenblatt, D.S.1
Erbe, R.W.2
|