Structure and function of the dihydropteroate synthase from Staphylococcus aureus

Journal of Molecular Biology

Volumn 268, Issue 1, 1997, Pages 21-30

  Hampele, Isabelle C ^a   D'Arcy, Allan ^a   Dale, Glenn E ^a   Kostrewa, Dirk ^a   Nielsen, Jørgen ^a   Oefner, Christian ^a   Page, Malcolm G P ^a   Schönfeld, Hans Joachim ^a   Stüber, Dietrich ^a   Then, Rudolf L ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

DHPS; Kinetics; S. aureus; Sulfonamide resistance; X ray structure

Indexed keywords

BACTERIAL ENZYME; DIHYDROPTEROATE SYNTHASE; DIMER; HYDROXYMETHYLPTERIN PYROPHOSPHATE; PTERIN DERIVATIVE; SULFANILAMIDE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; CLONING; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG RESISTANCE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; GENE EXPRESSION; GENE SEQUENCE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STEREOCHEMISTRY; X RAY CRYSTALLOGRAPHY;

EID: 0031585986     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.0944     Document Type: Editorial

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