A bacterial model for studying effects of human mutations in vivo: Escherichia coli strains mimicking a common polymorphism in the human MTHFR gene

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 578, Issue 1-2, 2005, Pages 175-186

  Jakóbkiewicz Banecka, Joanna ^a   Kloska, Anna ^b   Stepnowska, Magdalena ^b,c   Banecki, Bogdan ^b   Wȩgrzyn, Alicja ^a   Wȩgrzyn, Grzegorz ^b  

^a INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^b UNIVERSITY OF GDA SK   (Poland)

^c MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

5,10 Methylenetetrahydrofolate reductase; Escherichia coli metF gene; Human MTHFR gene; Hyperhomocysteinemia; MTHFR polymorphism

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYANOCOBALAMIN; DIMER; FOLIC ACID; GENE PRODUCT; HOMOCYSTEINE; POLYPEPTIDE; RIBOFLAVIN; TETRAMER;

ALLELE; AMINO ACID BLOOD LEVEL; AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL CELL; BACTERIAL STRAIN; CELL MUTANT; CHROMOSOME; CONTROLLED STUDY; DNA POLYMORPHISM; ESCHERICHIA COLI; GENE CONSTRUCT; GENETIC CODE; GENETIC VARIABILITY; HETEROZYGOTE; HOMOZYGOTE; MEROZOITE; NONHUMAN; ORTHOLOGY; PLASMID; PRIORITY JOURNAL; PROTEIN STRUCTURE; PUBLICATION; RECESSIVE GENE; WILD TYPE;

BACTERIAL PROTEINS; ESCHERICHIA COLI; GENES, BACTERIAL; HUMANS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MODELS, GENETIC; MUTATION; POLYMORPHISM, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 25844431603     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2005.05.002     Document Type: Article

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