-
1
-
-
0034041033
-
Immunobiology of dendritic cells
-
Banchereau, J. et al. 2000. Immunobiology of dendritic cells. Annu. Rev. Immunol. 18: 767-811.
-
(2000)
Annu. Rev. Immunol
, vol.18
, pp. 767-811
-
-
Banchereau, J.1
-
2
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri, G. 2003. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3: 133-146.
-
(2003)
Nat. Rev. Immunol
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
3
-
-
84864124859
-
IL-12 family cytokines: immunological playmakers
-
Vignali, D.A. & V.K. Kuchroo 2012. IL-12 family cytokines: immunological playmakers. Nat. Immunol. 13: 722-728.
-
(2012)
Nat. Immunol
, vol.13
, pp. 722-728
-
-
Vignali, D.A.1
Kuchroo, V.K.2
-
4
-
-
10644262982
-
Plasmacytoid dendritic cells: linking innate and adaptive immunity
-
McKenna, K., A.S. Beignon & N. Bhardwaj 2005. Plasmacytoid dendritic cells: linking innate and adaptive immunity. J. Virol. 79: 17-27.
-
(2005)
J. Virol
, vol.79
, pp. 17-27
-
-
McKenna, K.1
Beignon, A.S.2
Bhardwaj, N.3
-
5
-
-
84865782519
-
Harnessing human plasmacytoid dendritic cells as professional APCs
-
Tel, J. et al. 2012. Harnessing human plasmacytoid dendritic cells as professional APCs. Cancer Immunol. Immunother. 61: 1279-1288.
-
(2012)
Cancer Immunol. Immunother
, vol.61
, pp. 1279-1288
-
-
Tel, J.1
-
6
-
-
0038744443
-
Plasmacytoid dendritic cells prime IFN-gamma-secreting melanoma-specific CD8 lymphocytes and are found in primary melanoma lesions
-
Salio, M. et al. 2003. Plasmacytoid dendritic cells prime IFN-gamma-secreting melanoma-specific CD8 lymphocytes and are found in primary melanoma lesions. Eur. J. Immunol. 33: 1052-1062.
-
(2003)
Eur. J. Immunol
, vol.33
, pp. 1052-1062
-
-
Salio, M.1
-
7
-
-
22144465860
-
A critical function for type I interferons in cancer immunoediting
-
Dunn, G. P. et al. 2005. A critical function for type I interferons in cancer immunoediting. Nat. Immunol. 6: 722-729.
-
(2005)
Nat. Immunol
, vol.6
, pp. 722-729
-
-
Dunn, G.P.1
-
8
-
-
0141953994
-
Identification and functional analysis of tumor-infiltrating plasmacytoid dendritic cells in head and neck cancer
-
Hartmann, E. et al. 2003. Identification and functional analysis of tumor-infiltrating plasmacytoid dendritic cells in head and neck cancer. Cancer Res. 63: 6478-6487.
-
(2003)
Cancer Res
, vol.63
, pp. 6478-6487
-
-
Hartmann, E.1
-
9
-
-
35248847969
-
Plasmacytoid dendritic cells represent a major dendritic cell subset in sentinel lymph nodes of melanoma patients and accumulate in metastatic nodes
-
Gerlini, G. et al. 2007. Plasmacytoid dendritic cells represent a major dendritic cell subset in sentinel lymph nodes of melanoma patients and accumulate in metastatic nodes. Clin. Immunol. 125: 184-193.
-
(2007)
Clin. Immunol
, vol.125
, pp. 184-193
-
-
Gerlini, G.1
-
10
-
-
67649655988
-
Metastatic tumour cells favour the generation of a tolerogenic milieu in tumour draining lymph node in patients with early cervical cancer
-
Battaglia, A. et al. 2009. Metastatic tumour cells favour the generation of a tolerogenic milieu in tumour draining lymph node in patients with early cervical cancer. Cancer Immunol. Immunother. 58: 1363-1373.
-
(2009)
Cancer Immunol. Immunother
, vol.58
, pp. 1363-1373
-
-
Battaglia, A.1
-
11
-
-
34848915783
-
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase
-
Sharma, M.D. et al. 2007. Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2, 3-dioxygenase. J. Clin, Invest. 117: 2570-2582.
-
(2007)
J. Clin, Invest
, vol.117
, pp. 2570-2582
-
-
Sharma, M.D.1
-
12
-
-
4043092238
-
Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes
-
Munn, D.H. et al. 2004. Expression of indoleamine 2, 3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J. Clin. Invest. 114: 280-290.
-
(2004)
J. Clin. Invest
, vol.114
, pp. 280-290
-
-
Munn, D.H.1
-
13
-
-
0036214292
-
Antigen presentation and T cell stimulation by dendritic cells
-
Guermonprez, P. et al. 2002. Antigen presentation and T cell stimulation by dendritic cells. Annu. Rev. Immunol. 20: 621-667.
-
(2002)
Annu. Rev. Immunol
, vol.20
, pp. 621-667
-
-
Guermonprez, P.1
-
14
-
-
84864332935
-
Cross-presentation by dendritic cells. Nature reviews
-
Joffre, O.P. et al. 2012. Cross-presentation by dendritic cells. Nature reviews. Immunology 12: 557-569.
-
(2012)
Immunology
, vol.12
, pp. 557-569
-
-
Joffre, O.P.1
-
16
-
-
53249132649
-
Dendritic cells and C-type lectin receptors: coupling innate to adaptive immune responses
-
van Vliet, S.J., J.J. Garcia-Vallejo & Y. van Kooyk 2008. Dendritic cells and C-type lectin receptors: coupling innate to adaptive immune responses. Immunol. Cell Biol. 86: 580-587.
-
(2008)
Immunol. Cell Biol
, vol.86
, pp. 580-587
-
-
van Vliet, S.J.1
Garcia-Vallejo, J.J.2
van Kooyk, Y.3
-
17
-
-
79952311653
-
Inhibitory C-type lectin receptors in myeloid cells
-
Redelinghuys, P. & G.D. Brown 2011. Inhibitory C-type lectin receptors in myeloid cells. Immunol, Lett. 136: 1-12.
-
(2011)
Immunol, Lett
, vol.136
, pp. 1-12
-
-
Redelinghuys, P.1
Brown, G.D.2
-
18
-
-
3142724031
-
Toll-like receptor signalling
-
Akira, S. & K. Takeda 2004. Toll-like receptor signalling. Nat. Rev. Immunol. 4: 499-511.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
19
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato, H. et al. 2006. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441: 101-105.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
-
22
-
-
15944383257
-
Dendritic cells control B cell growth and differentiation
-
Jego, G. et al. 2005. Dendritic cells control B cell growth and differentiation. Curr. Dir. Autoimmun. 8: 124-139.
-
(2005)
Curr. Dir. Autoimmun
, vol.8
, pp. 124-139
-
-
Jego, G.1
-
23
-
-
11144234196
-
Mature myeloid dendritic cell subsets have distinct roles for activation and viability of circulating human natural killer cells
-
Munz, C. et al. 2005. Mature myeloid dendritic cell subsets have distinct roles for activation and viability of circulating human natural killer cells. Blood 105: 266-273.
-
(2005)
Blood
, vol.105
, pp. 266-273
-
-
Munz, C.1
-
24
-
-
0036735859
-
Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs
-
Fujii, S. et al. 2002. Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs. Nat. Immunol. 3: 867-874.
-
(2002)
Nat. Immunol
, vol.3
, pp. 867-874
-
-
Fujii, S.1
-
25
-
-
14144253045
-
Apoptotic cells at the crossroads of tolerance and immunity
-
Skoberne, M. et al. 2005. Apoptotic cells at the crossroads of tolerance and immunity. Curr. Top. Microbiol. Immunol. 289: 259-292.
-
(2005)
Curr. Top. Microbiol. Immunol
, vol.289
, pp. 259-292
-
-
Skoberne, M.1
-
26
-
-
35549004528
-
Balancing between immunity and tolerance: an interplay between dendritic cells, regulatory T cells, and effector T cells
-
Cools, N. et al. 2007. Balancing between immunity and tolerance: an interplay between dendritic cells, regulatory T cells, and effector T cells. J. Leukoc. Biol. 82: 1365-1374.
-
(2007)
J. Leukoc. Biol
, vol.82
, pp. 1365-1374
-
-
Cools, N.1
-
27
-
-
5044220930
-
IDO expression by dendritic cells: tolerance and tryptophan catabolism
-
Mellor, A.L. & D.H. Munn 2004. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat. Rev. Immunol. 4: 762-774.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 762-774
-
-
Mellor, A.L.1
Munn, D.H.2
-
28
-
-
0842286646
-
IDO and tolerance to tumors
-
Munn, D.H. & A.L. Mellor 2004. IDO and tolerance to tumors. Trends Mol. Med. 10: 15-18.
-
(2004)
Trends Mol. Med
, vol.10
, pp. 15-18
-
-
Munn, D.H.1
Mellor, A.L.2
-
29
-
-
12844274909
-
+ Tr cells
-
+ Tr cells. Blood 105: 1162-1169.
-
(2005)
Blood
, vol.105
, pp. 1162-1169
-
-
Levings, M.K.1
-
30
-
-
0034613767
-
Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
-
Jonuleit, H. et al. 2000. Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192: 1213-1222.
-
(2000)
J. Exp. Med
, vol.192
, pp. 1213-1222
-
-
Jonuleit, H.1
-
31
-
-
0035874949
-
Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
-
Woo, E.Y. et al. 2001. Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res. 61: 4766-4772.
-
(2001)
Cancer Res
, vol.61
, pp. 4766-4772
-
-
Woo, E.Y.1
-
32
-
-
0036721629
-
Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
-
Liyanage, U.K. et al. 2002. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J. Immunol. 169: 2756-2761.
-
(2002)
J. Immunol
, vol.169
, pp. 2756-2761
-
-
Liyanage, U.K.1
-
33
-
-
39449126502
-
+ regulatory T cell: a jack of all trades, master of regulation
-
+ regulatory T cell: a jack of all trades, master of regulation. Nat. Immunol. 9: 239-244.
-
(2008)
Nat. Immunol
, vol.9
, pp. 239-244
-
-
Tang, Q.1
Bluestone, J.A.2
-
34
-
-
33746618323
-
The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function
-
Skoberne, M. et al. 2006. The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function. Blood 108: 947-955.
-
(2006)
Blood
, vol.108
, pp. 947-955
-
-
Skoberne, M.1
-
35
-
-
84870484583
-
HIV-1 infection-induced apoptotic microparticles inhibit human DCs via CD44
-
Frleta, D. et al. 2012. HIV-1 infection-induced apoptotic microparticles inhibit human DCs via CD44. J. Clin. Invest. 122: 4685-4697.
-
(2012)
J. Clin. Invest
, vol.122
, pp. 4685-4697
-
-
Frleta, D.1
-
36
-
-
84855337070
-
How vitamin A metabolizing dendritic cells are generated in the gut mucosa
-
Agace, W.W. & E.K. Persson 2012. How vitamin A metabolizing dendritic cells are generated in the gut mucosa. Trends Immunol. 33: 42-48.
-
(2012)
Trends Immunol
, vol.33
, pp. 42-48
-
-
Agace, W.W.1
Persson, E.K.2
-
37
-
-
33748335363
-
Spontaneous regression of melanoma with distant metastases-report of a patient with brain metastases
-
Satzger, I. et al. 2006. Spontaneous regression of melanoma with distant metastases-report of a patient with brain metastases. Eur. J. Dermatol. 16: 454-455.
-
(2006)
Eur. J. Dermatol
, vol.16
, pp. 454-455
-
-
Satzger, I.1
-
38
-
-
0032880649
-
Human tumor antigens for cancer vaccine development
-
Wang, R.F. & S.A. Rosenberg 1999. Human tumor antigens for cancer vaccine development. Immunol. Rev. 170: 85-100.
-
(1999)
Immunol. Rev
, vol.170
, pp. 85-100
-
-
Wang, R.F.1
Rosenberg, S.A.2
-
39
-
-
34047220868
-
Cancer immunoediting from immune surveillance to immune escape
-
Kim, R., M. Emi & K. Tanabe 2007. Cancer immunoediting from immune surveillance to immune escape. Immunology 121: 1-14.
-
(2007)
Immunology
, vol.121
, pp. 1-14
-
-
Kim, R.1
Emi, M.2
Tanabe, K.3
-
40
-
-
84858800620
-
The immune contexture in human tumours: impact on clinical outcome. Nature reviews
-
Fridman, W.H. et al. 2012. The immune contexture in human tumours: impact on clinical outcome. Nature reviews. Cancer 12: 298-306.
-
(2012)
Cancer
, vol.12
, pp. 298-306
-
-
Fridman, W.H.1
-
41
-
-
84857596771
-
Conference scene: immune effector mechanisms in tumor immunity
-
Sikora, A.G., Y. Hailemichael & W.W. Overwijk 2012. Conference scene: immune effector mechanisms in tumor immunity. Immunotherapy 4: 141-143.
-
(2012)
Immunotherapy
, vol.4
, pp. 141-143
-
-
Sikora, A.G.1
Hailemichael, Y.2
Overwijk, W.W.3
-
42
-
-
70349299844
-
A randomized therapeutic vaccine trial of canarypox-HIV-pulsed dendritic cells vs. canarypox-HIV alone in HIV-1-infected patients on antiretroviral therapy
-
Gandhi, R.T. et al. 2009. A randomized therapeutic vaccine trial of canarypox-HIV-pulsed dendritic cells vs. canarypox-HIV alone in HIV-1-infected patients on antiretroviral therapy. Vaccine 27: 6088-6094.
-
(2009)
Vaccine
, vol.27
, pp. 6088-6094
-
-
Gandhi, R.T.1
-
43
-
-
33748693100
-
Dendritic cells loaded with killed allogeneic melanoma cells can induce objective clinical responses and MART-1 specific CD8+ T-cell immunity
-
Palucka, A.K. et al. 2006. Dendritic cells loaded with killed allogeneic melanoma cells can induce objective clinical responses and MART-1 specific CD8+ T-cell immunity. J. Immunother. 29: 545-557.
-
(2006)
J. Immunother
, vol.29
, pp. 545-557
-
-
Palucka, A.K.1
-
44
-
-
48549095277
-
Phase Ib trial assessing autologous, tumor-pulsed dendritic cells as a vaccine administered with or without IL-2 in patients with metastatic melanoma
-
Redman, B.G. et al. 2008. Phase Ib trial assessing autologous, tumor-pulsed dendritic cells as a vaccine administered with or without IL-2 in patients with metastatic melanoma. J. Immunother. 31: 591-598.
-
(2008)
J. Immunother
, vol.31
, pp. 591-598
-
-
Redman, B.G.1
-
45
-
-
44449088893
-
Differentiation of peripheral blood monocytes into dendritic cells
-
Chapter 22: Unit 22F 24.
-
O'Neill, D.W. & N. Bhardwaj 2005. Differentiation of peripheral blood monocytes into dendritic cells. Curr. Protoc. Immunol. Chapter 22: Unit 22F 24.
-
(2005)
Curr. Protoc. Immunol
-
-
O'Neill, D.W.1
Bhardwaj, N.2
-
46
-
-
16644372532
-
Generation of autologous peptide- and protein-pulsed dendritic cells for patient-specific immunotherapy
-
O'Neill, D. & N. Bhardwaj 2005. Generation of autologous peptide- and protein-pulsed dendritic cells for patient-specific immunotherapy. Methods Mol. Med. 109: 97-112.
-
(2005)
Methods Mol. Med
, vol.109
, pp. 97-112
-
-
O'Neill, D.1
Bhardwaj, N.2
-
47
-
-
0035417932
-
Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine
-
Banchereau, J. et al. 2001. Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine. Cancer Res. 61: 6451-6458.
-
(2001)
Cancer Res
, vol.61
, pp. 6451-6458
-
-
Banchereau, J.1
-
48
-
-
65049088736
-
Understanding human myeloid dendritic cell subsets for the rational design of novel vaccines
-
Klechevsky, E. et al. 2009. Understanding human myeloid dendritic cell subsets for the rational design of novel vaccines. Hum. Immunol. 70: 281-288.
-
(2009)
Hum. Immunol
, vol.70
, pp. 281-288
-
-
Klechevsky, E.1
-
49
-
-
79953324723
-
Peptide-loaded Langerhans cells, despite increased IL15 secretion and T-cell activation in vitro, elicit antitumor T-cell responses comparable to peptide-loaded monocyte-derived dendritic cells in vivo
-
Romano, E. et al. 2011. Peptide-loaded Langerhans cells, despite increased IL15 secretion and T-cell activation in vitro, elicit antitumor T-cell responses comparable to peptide-loaded monocyte-derived dendritic cells in vivo. Clin. Cancer Res. 17: 1984-1997.
-
(2011)
Clin. Cancer Res
, vol.17
, pp. 1984-1997
-
-
Romano, E.1
-
50
-
-
0036093631
-
Mobilization of dendritic cell precursors in patients with cancer by flt3 ligand allows the generation of higher yields of cultured dendritic cells
-
Marroquin, C.E. et al. 2002. Mobilization of dendritic cell precursors in patients with cancer by flt3 ligand allows the generation of higher yields of cultured dendritic cells. J. Immunother. 25: 278-288.
-
(2002)
J. Immunother
, vol.25
, pp. 278-288
-
-
Marroquin, C.E.1
-
51
-
-
0034235748
-
Flt3-ligand and granulocyte colony-stimulating factor mobilize distinct human dendritic cell subsets in vivo
-
Pulendran, B. et al. 2000. Flt3-ligand and granulocyte colony-stimulating factor mobilize distinct human dendritic cell subsets in vivo. J. Immunol. 165: 566-572.
-
(2000)
J. Immunol
, vol.165
, pp. 566-572
-
-
Pulendran, B.1
-
52
-
-
77951924326
-
In vivo role of Flt3 ligand and dendritic cells in NK cell homeostasis
-
Guimond, M. et al. 2010. In vivo role of Flt3 ligand and dendritic cells in NK cell homeostasis. J. Immunol. 184: 2769-2775.
-
(2010)
J. Immunol
, vol.184
, pp. 2769-2775
-
-
Guimond, M.1
-
53
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff, P.W. et al. 2010. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N. Engl. J. Med. 363: 411-422.
-
(2010)
N. Engl. J. Med
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
-
54
-
-
33746012881
-
Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer
-
Small, E.J. et al. 2006. Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer. J. Clin. Oncol. 24: 3089-3094.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 3089-3094
-
-
Small, E.J.1
-
55
-
-
0037226599
-
Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state
-
De Vries, I. J. et al. 2003. Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res. 63: 12-17.
-
(2003)
Cancer Res
, vol.63
, pp. 12-17
-
-
De Vries, I.J.1
-
56
-
-
0035862333
-
Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells
-
Dhodapkar, M.V. et al. 2001. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J. Exp. Med. 193: 233-238.
-
(2001)
J. Exp. Med
, vol.193
, pp. 233-238
-
-
Dhodapkar, M.V.1
-
57
-
-
0036659913
-
Antigen-bearing immature dendritic cells induce peptide-specific CD8(+) regulatory T cells in vivo in humans
-
Dhodapkar, M.V. & R.M. Steinman 2002. Antigen-bearing immature dendritic cells induce peptide-specific CD8(+) regulatory T cells in vivo in humans. Blood 100: 174-177.
-
(2002)
Blood
, vol.100
, pp. 174-177
-
-
Dhodapkar, M.V.1
Steinman, R.M.2
-
58
-
-
10744224631
-
Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients
-
de Vries, I.J. et al. 2003. Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients. Clin. Cancer Res. 9: 5091-5100.
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 5091-5100
-
-
de Vries, I.J.1
-
59
-
-
0037137573
-
A clinical grade cocktail of cytokines and PGE2 results in uniform maturation of human monocyte-derived dendritic cells: implications for immunotherapy
-
Lee, A.W. et al. 2002. A clinical grade cocktail of cytokines and PGE2 results in uniform maturation of human monocyte-derived dendritic cells: implications for immunotherapy. Vaccine 20 (Suppl. 4): A8-A22.
-
(2002)
Vaccine
, vol.20
, Issue.SUPPL. 4
-
-
Lee, A.W.1
-
60
-
-
24144495503
-
Th1-polarizing capacity of clinical-grade dendritic cells is triggered by Ribomunyl but is compromised by PGE2: the importance of maturation cocktails
-
Jongmans, W. et al. 2005. Th1-polarizing capacity of clinical-grade dendritic cells is triggered by Ribomunyl but is compromised by PGE2: the importance of maturation cocktails. J. Immunother. 28: 480-487.
-
(2005)
J. Immunother
, vol.28
, pp. 480-487
-
-
Jongmans, W.1
-
61
-
-
36248944552
-
Prostaglandin E2 is a key factor for monocyte-derived dendritic cell maturation: enhanced T cell stimulatory capacity despite IDO
-
Krause, P. et al. 2007. Prostaglandin E2 is a key factor for monocyte-derived dendritic cell maturation: enhanced T cell stimulatory capacity despite IDO. J. Leukoc. Biol. 82: 1106-1114.
-
(2007)
J. Leukoc. Biol
, vol.82
, pp. 1106-1114
-
-
Krause, P.1
-
62
-
-
0037373670
-
Dendritic cells under the spell of prostaglandins
-
Morelli, A.E. & A.W. Thomson 2003. Dendritic cells under the spell of prostaglandins. Trends Immunol. 24: 108-111.
-
(2003)
Trends Immunol
, vol.24
, pp. 108-111
-
-
Morelli, A.E.1
Thomson, A.W.2
-
63
-
-
6344275644
-
Prostaglandin E2-dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix
-
Baratelli, F.E. et al. 2004. Prostaglandin E2-dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix. J. Immunol. 173: 5458-5466.
-
(2004)
J. Immunol
, vol.173
, pp. 5458-5466
-
-
Baratelli, F.E.1
-
64
-
-
0037103366
-
Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells
-
Scandella, E. et al. 2002. Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells. Blood 100: 1354-1361.
-
(2002)
Blood
, vol.100
, pp. 1354-1361
-
-
Scandella, E.1
-
65
-
-
64049097483
-
Prostaglandin E(2) enhances T-cell proliferation by inducing the costimulatory molecules OX40L, CD70, and 4-1BBL on dendritic cells
-
Krause, P. et al. 2009. Prostaglandin E(2) enhances T-cell proliferation by inducing the costimulatory molecules OX40L, CD70, and 4-1BBL on dendritic cells. Blood 113: 2451-2460.
-
(2009)
Blood
, vol.113
, pp. 2451-2460
-
-
Krause, P.1
-
66
-
-
84857777282
-
Distinct TLR adjuvants differentially stimulate systemic and local innate immune responses in nonhuman primates
-
Kwissa, M. et al. 2012. Distinct TLR adjuvants differentially stimulate systemic and local innate immune responses in nonhuman primates. Blood 119: 2044-2055.
-
(2012)
Blood
, vol.119
, pp. 2044-2055
-
-
Kwissa, M.1
-
67
-
-
0034775153
-
Toll-like receptors control activation of adaptive immune responses
-
Schnare, M. et al. 2001. Toll-like receptors control activation of adaptive immune responses. Nat. Immunol. 2: 947-950.
-
(2001)
Nat. Immunol
, vol.2
, pp. 947-950
-
-
Schnare, M.1
-
68
-
-
23944489407
-
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
-
Napolitani, G. et al. 2005. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat. Immunol. 6: 769-776.
-
(2005)
Nat. Immunol
, vol.6
, pp. 769-776
-
-
Napolitani, G.1
-
69
-
-
50649089811
-
Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration
-
Boullart, A.C. et al. 2008. Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration. Cancer Immunol. Immunother. 57: 1589-1597.
-
(2008)
Cancer Immunol. Immunother
, vol.57
, pp. 1589-1597
-
-
Boullart, A.C.1
-
70
-
-
4344596051
-
alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity
-
Mailliard, R.B. et al. 2004. alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity. Cancer Res. 64: 5934-5937.
-
(2004)
Cancer Res
, vol.64
, pp. 5934-5937
-
-
Mailliard, R.B.1
-
71
-
-
46949095104
-
Type 1-polarized dendritic cells loaded with autologous tumor are a potent immunogen against chronic lymphocytic leukemia
-
Lee, J.J. et al. 2008. Type 1-polarized dendritic cells loaded with autologous tumor are a potent immunogen against chronic lymphocytic leukemia. J. Leukoc. Biol. 84: 319-325.
-
(2008)
J. Leukoc. Biol
, vol.84
, pp. 319-325
-
-
Lee, J.J.1
-
72
-
-
79951978155
-
+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma
-
+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma. J. Clin. Oncol. 29: 330-336.
-
(2011)
J. Clin. Oncol
, vol.29
, pp. 330-336
-
-
Okada, H.1
-
73
-
-
0042922810
-
Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming
-
MartIn-Fontecha, A. et al. 2003. Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J. Exp. Med. 198: 615-621.
-
(2003)
J. Exp. Med
, vol.198
, pp. 615-621
-
-
MartIn-Fontecha, A.1
-
74
-
-
47949129948
-
Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvant
-
Adams, S. et al. 2008. Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvant. J. Immunol. 181: 776-784.
-
(2008)
J. Immunol
, vol.181
, pp. 776-784
-
-
Adams, S.1
-
75
-
-
0345447557
-
Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation
-
Nair, S. et al. 2003. Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation. J. Immunol. 171: 6275-6282.
-
(2003)
J. Immunol
, vol.171
, pp. 6275-6282
-
-
Nair, S.1
-
76
-
-
42549138499
-
Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines
-
Melief, C.J. & S.H. van der Burg 2008. Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines. Nat. Rev. Cancer 8: 351-360.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 351-360
-
-
Melief, C.J.1
van der Burg, S.H.2
-
77
-
-
44849109375
-
Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation
-
Bijker, M.S. et al. 2008. Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation. Eur. J. Immunol. 38: 1033-1042.
-
(2008)
Eur. J. Immunol
, vol.38
, pp. 1033-1042
-
-
Bijker, M.S.1
-
78
-
-
40549129230
-
Phase I immunotherapeutic trial with long peptides spanning the E6 and E7 sequences of high-risk human papillomavirus 16 in end-stage cervical cancer patients shows low toxicity and robust immunogenicity
-
Kenter, G.G. et al. 2008. Phase I immunotherapeutic trial with long peptides spanning the E6 and E7 sequences of high-risk human papillomavirus 16 in end-stage cervical cancer patients shows low toxicity and robust immunogenicity. Clin. Cancer Res. 14: 169-177.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 169-177
-
-
Kenter, G.G.1
-
79
-
-
40549110815
-
+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine
-
+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine. Clin. Cancer Res. 14: 178-187.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 178-187
-
-
Welters, M.J.1
-
80
-
-
70350772293
-
Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia
-
Kenter, G.G. et al. 2009. Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia. N. Engl. J. Med. 361: 1838-1847.
-
(2009)
N. Engl. J. Med
, vol.361
, pp. 1838-1847
-
-
Kenter, G.G.1
-
81
-
-
84866538193
-
A placebo-controlled randomized HPV16 synthetic long-peptide vaccination study in women with high-grade cervical squamous intraepithelial lesions
-
de Vos van Steenwijk, P.J. et al. 2012. A placebo-controlled randomized HPV16 synthetic long-peptide vaccination study in women with high-grade cervical squamous intraepithelial lesions. Cancer Immunol. Immunother. 61: 1485-1492.
-
(2012)
Cancer Immunol. Immunother
, vol.61
, pp. 1485-1492
-
-
de Vos van Steenwijk, P.J.1
-
82
-
-
70249141312
-
Immunization with a P53 synthetic long peptide vaccine induces P53-specific immune responses in ovarian cancer patients, a phase II trial
-
Leffers, N. et al. 2009. Immunization with a P53 synthetic long peptide vaccine induces P53-specific immune responses in ovarian cancer patients, a phase II trial. Int. J. Cancer 125: 2104-2113.
-
(2009)
Int. J. Cancer
, vol.125
, pp. 2104-2113
-
-
Leffers, N.1
-
83
-
-
84870359509
-
Phase I trial of overlapping long peptides from a tumor self-antigen and poly-ICLC shows rapid induction of integrated immune response in ovarian cancer patients
-
Sabbatini, P. et al. 2012. Phase I trial of overlapping long peptides from a tumor self-antigen and poly-ICLC shows rapid induction of integrated immune response in ovarian cancer patients. Clin. Cancer Res. 18: 6497-6508.
-
(2012)
Clin. Cancer Res
, vol.18
, pp. 6497-6508
-
-
Sabbatini, P.1
-
84
-
-
84873081589
-
Addition of interferon-alpha to the p53-SLP(R) vaccine results in increased production of interferon-gamma in vaccinated colorectal cancer patients: a phase I/II clinical trial
-
Zeestraten, E.C. et al. 2013. Addition of interferon-alpha to the p53-SLP(R) vaccine results in increased production of interferon-gamma in vaccinated colorectal cancer patients: a phase I/II clinical trial. Int. J. Cancer 132: 1581-1591.
-
(2013)
Int. J. Cancer
, vol.132
, pp. 1581-1591
-
-
Zeestraten, E.C.1
-
85
-
-
61349184597
-
Induction of p53-specific immunity by a p53 synthetic long peptide vaccine in patients treated for metastatic colorectal cancer
-
Speetjens, F.M. et al. 2009. Induction of p53-specific immunity by a p53 synthetic long peptide vaccine in patients treated for metastatic colorectal cancer. Clin. Cancer Res. 15: 1086-1095.
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 1086-1095
-
-
Speetjens, F.M.1
-
86
-
-
84855342224
-
Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques
-
Rosario, M. et al. 2012. Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques. Aids 26: 275-284.
-
(2012)
Aids
, vol.26
, pp. 275-284
-
-
Rosario, M.1
-
87
-
-
2342640119
-
Vaccination of prostatectomized prostate cancer patients in biochemical relapse, with autologous dendritic cells pulsed with recombinant human PSA
-
Barrou, B. et al. 2004. Vaccination of prostatectomized prostate cancer patients in biochemical relapse, with autologous dendritic cells pulsed with recombinant human PSA. Cancer Immunol. Immunother. 53: 453-460.
-
(2004)
Cancer Immunol. Immunother
, vol.53
, pp. 453-460
-
-
Barrou, B.1
-
88
-
-
33645297917
-
Vaccination of melanoma patients using dendritic cells loaded with an allogeneic tumor cell lysate
-
Salcedo, M. et al. 2006. Vaccination of melanoma patients using dendritic cells loaded with an allogeneic tumor cell lysate. Cancer Immunol. Immunother. 55: 819-829.
-
(2006)
Cancer Immunol. Immunother
, vol.55
, pp. 819-829
-
-
Salcedo, M.1
-
89
-
-
33646880439
-
Dendritic cells, pulsed with lysate of allogeneic tumor cells, are capable of stimulating MHC-restricted antigen-specific antitumor T cells
-
Mahdian, R. et al. 2006. Dendritic cells, pulsed with lysate of allogeneic tumor cells, are capable of stimulating MHC-restricted antigen-specific antitumor T cells. Med. Oncol. 23: 273-282.
-
(2006)
Med. Oncol
, vol.23
, pp. 273-282
-
-
Mahdian, R.1
-
90
-
-
0035418241
-
Tumor cell lysate-pulsed human dendritic cells induce a T-cell response against pancreatic carcinoma cells: an in vitro model for the assessment of tumor vaccines
-
Schnurr, M. et al. 2001. Tumor cell lysate-pulsed human dendritic cells induce a T-cell response against pancreatic carcinoma cells: an in vitro model for the assessment of tumor vaccines. Cancer Res. 61: 6445-6450.
-
(2001)
Cancer Res
, vol.61
, pp. 6445-6450
-
-
Schnurr, M.1
-
91
-
-
0038208181
-
Antigen loading of dendritic cells with whole tumor cell preparations
-
Thumann, P. et al. 2003. Antigen loading of dendritic cells with whole tumor cell preparations. J. Immunol. Methods 277: 1-16.
-
(2003)
J. Immunol. Methods
, vol.277
, pp. 1-16
-
-
Thumann, P.1
-
92
-
-
0036705263
-
Technology evaluation: DCVax, Northwest Biotherapeutics
-
Knutson, K.L. 2002. Technology evaluation: DCVax, Northwest Biotherapeutics. Curr. Opin. Mol. Ther. 4: 403-407.
-
(2002)
Curr. Opin. Mol. Ther
, vol.4
, pp. 403-407
-
-
Knutson, K.L.1
-
93
-
-
84874625308
-
Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer
-
Kandalaft, L.E. et al. 2013. Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer. Oncoimmunology 2: e22664.
-
(2013)
Oncoimmunology
, vol.2
-
-
Kandalaft, L.E.1
-
94
-
-
20144382346
-
Tumor antigen processing and presentation depend critically on dendritic cell type and the mode of antigen delivery
-
Schnurr, M. et al. 2005. Tumor antigen processing and presentation depend critically on dendritic cell type and the mode of antigen delivery. Blood 105: 2465-2472.
-
(2005)
Blood
, vol.105
, pp. 2465-2472
-
-
Schnurr, M.1
-
95
-
-
0034913277
-
Viral vectors for dendritic cell-based immunotherapy
-
Jenne, L., G. Schuler & A. Steinkasserer 2001. Viral vectors for dendritic cell-based immunotherapy. Trends Immunol. 22: 102-107.
-
(2001)
Trends Immunol
, vol.22
, pp. 102-107
-
-
Jenne, L.1
Schuler, G.2
Steinkasserer, A.3
-
96
-
-
51349108306
-
Promises and challenges for the development of Listeria monocytogenes-based immunotherapies
-
Brockstedt, D.G. & T.W. Dubensky 2008. Promises and challenges for the development of Listeria monocytogenes-based immunotherapies. Expert Rev. Vaccines 7: 1069-1084.
-
(2008)
Expert Rev. Vaccines
, vol.7
, pp. 1069-1084
-
-
Brockstedt, D.G.1
Dubensky, T.W.2
-
97
-
-
67449094695
-
Human papillomavirus type 16 (HPV-16) virus-like particle L1-specific CD8+ cytotoxic T lymphocytes (CTLs) are equally effective as E7-specific CD8+ CTLs in killing autologous HPV-16-positive tumor cells in cervical cancer patients: implications for L1 dendritic cell-based therapeutic vaccines
-
Bellone, S. et al. 2009. Human papillomavirus type 16 (HPV-16) virus-like particle L1-specific CD8+ cytotoxic T lymphocytes (CTLs) are equally effective as E7-specific CD8+ CTLs in killing autologous HPV-16-positive tumor cells in cervical cancer patients: implications for L1 dendritic cell-based therapeutic vaccines. J. Virol. 83: 6779-6789.
-
(2009)
J. Virol
, vol.83
, pp. 6779-6789
-
-
Bellone, S.1
-
98
-
-
49149115482
-
Vaccination of a melanoma patient with mature dendritic cells pulsed with MAGE-3 peptides triggers the activity of nonvaccine anti-tumor cells
-
Carrasco, J. et al. 2008. Vaccination of a melanoma patient with mature dendritic cells pulsed with MAGE-3 peptides triggers the activity of nonvaccine anti-tumor cells. J. Immunol. 180: 3585-3593.
-
(2008)
J. Immunol
, vol.180
, pp. 3585-3593
-
-
Carrasco, J.1
-
99
-
-
41149164895
-
Adenovirus MART-1-engineered autologous dendritic cell vaccine for metastatic melanoma
-
Butterfield, L.H. et al. 2008. Adenovirus MART-1-engineered autologous dendritic cell vaccine for metastatic melanoma. J. Immunother. 31: 294-309.
-
(2008)
J. Immunother
, vol.31
, pp. 294-309
-
-
Butterfield, L.H.1
-
100
-
-
34248395538
-
Major subsets of human dendritic cells are efficiently transduced by self-complementary adeno-associated virus vectors 1 and 2
-
Veron, P. et al. 2007. Major subsets of human dendritic cells are efficiently transduced by self-complementary adeno-associated virus vectors 1 and 2. J. Virol. 81: 5385-5394.
-
(2007)
J. Virol
, vol.81
, pp. 5385-5394
-
-
Veron, P.1
-
101
-
-
57449114574
-
KBMA Listeria monocytogenes is an effective vector for DC-mediated induction of antitumor immunity
-
Skoberne, M. et al. 2008. KBMA Listeria monocytogenes is an effective vector for DC-mediated induction of antitumor immunity. J. Clin. Invest. 118: 3990-4001.
-
(2008)
J. Clin. Invest
, vol.118
, pp. 3990-4001
-
-
Skoberne, M.1
-
102
-
-
34249111217
-
Lentiviral vectors for cancer immunotherapy: transforming infectious particles into therapeutics
-
Breckpot, K., J.L. Aerts & K. Thielemans 2007. Lentiviral vectors for cancer immunotherapy: transforming infectious particles into therapeutics. Gene Ther. 14: 847-862.
-
(2007)
Gene Ther
, vol.14
, pp. 847-862
-
-
Breckpot, K.1
Aerts, J.L.2
Thielemans, K.3
-
103
-
-
37149001171
-
Recombinant lentivector as a genetic immunization vehicle for antitumor immunity
-
He, Y., D. Munn & L.D. Falo Jr. 2007. Recombinant lentivector as a genetic immunization vehicle for antitumor immunity. Expert Rev. Vaccines. 6: 913-924.
-
(2007)
Expert Rev. Vaccines
, vol.6
, pp. 913-924
-
-
He, Y.1
Munn, D.2
Falo Jr., L.D.3
-
104
-
-
0034135980
-
Transduction of human PBMC-derived dendritic cells and macrophages by an HIV-1-based lentiviral vector system
-
Schroers, R. et al. 2000. Transduction of human PBMC-derived dendritic cells and macrophages by an HIV-1-based lentiviral vector system. Mol. Ther. 1: 171-179.
-
(2000)
Mol. Ther
, vol.1
, pp. 171-179
-
-
Schroers, R.1
-
105
-
-
0035169569
-
Lentivirus-transduced human monocyte-derived dendritic cells efficiently stimulate antigen-specific cytotoxic T lymphocytes
-
Dyall, J. et al. 2001. Lentivirus-transduced human monocyte-derived dendritic cells efficiently stimulate antigen-specific cytotoxic T lymphocytes. Blood 97: 114-121.
-
(2001)
Blood
, vol.97
, pp. 114-121
-
-
Dyall, J.1
-
106
-
-
1842636260
-
Lentivirus vector-mediated expression of tumor-associated epitopes by human antigen presenting cells
-
Lizee, G., M.I. Gonzales & S.L. Topalian 2004. Lentivirus vector-mediated expression of tumor-associated epitopes by human antigen presenting cells. Hum. Gene Ther. 15: 393-404.
-
(2004)
Hum. Gene Ther
, vol.15
, pp. 393-404
-
-
Lizee, G.1
Gonzales, M.I.2
Topalian, S.L.3
-
107
-
-
84877779587
-
Efficient transduction of myeloid cells by an HIV-1-derived lentiviral vector that packages the Vpx accessory protein
-
Bobadilla, S., N. Sunseri & N.R. Landau 2012. Efficient transduction of myeloid cells by an HIV-1-derived lentiviral vector that packages the Vpx accessory protein. Gene Ther.
-
(2012)
Gene Ther
-
-
Bobadilla, S.1
Sunseri, N.2
Landau, N.R.3
-
108
-
-
0842321785
-
Identification of new antigenic peptide presented by HLA-Cw7 and encoded by several MAGE genes using dendritic cells transduced with lentiviruses
-
Breckpot, K. et al. 2004. Identification of new antigenic peptide presented by HLA-Cw7 and encoded by several MAGE genes using dendritic cells transduced with lentiviruses. J. Immunol. 172: 2232-2237.
-
(2004)
J. Immunol
, vol.172
, pp. 2232-2237
-
-
Breckpot, K.1
-
109
-
-
14844351569
-
Immunization with lentiviral vector-transduced dendritic cells induces strong and long-lasting T cell responses and therapeutic immunity
-
He, Y. et al. 2005. Immunization with lentiviral vector-transduced dendritic cells induces strong and long-lasting T cell responses and therapeutic immunity. J. Immunol. 174: 3808-3817.
-
(2005)
J. Immunol
, vol.174
, pp. 3808-3817
-
-
He, Y.1
-
110
-
-
33645098473
-
Induction of effective therapeutic antitumor immunity by direct in vivo administration of lentiviral vectors
-
Dullaers, M. et al. 2006. Induction of effective therapeutic antitumor immunity by direct in vivo administration of lentiviral vectors. Gene Ther. 13: 630-640.
-
(2006)
Gene Ther
, vol.13
, pp. 630-640
-
-
Dullaers, M.1
-
111
-
-
40449116336
-
Engineered lentivector targeting of dendritic cells for in vivo immunization
-
Yang, L. et al. 2008. Engineered lentivector targeting of dendritic cells for in vivo immunization. Nat. Biotechnol. 26: 326-334.
-
(2008)
Nat. Biotechnol
, vol.26
, pp. 326-334
-
-
Yang, L.1
-
112
-
-
0036203164
-
Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-transfected dendritic cells
-
Nair, S.K. et al. 2002. Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-transfected dendritic cells. Ann. Surg. 235: 540-549.
-
(2002)
Ann. Surg
, vol.235
, pp. 540-549
-
-
Nair, S.K.1
-
113
-
-
1442332361
-
Induction of chronic lymphocytic leukemia (CLL)-specific CD4- and CD8-mediated T-cell responses using RNA-transfected dendritic cells
-
Muller, M.R. et al. 2004. Induction of chronic lymphocytic leukemia (CLL)-specific CD4- and CD8-mediated T-cell responses using RNA-transfected dendritic cells. Blood 103: 1763-1769.
-
(2004)
Blood
, vol.103
, pp. 1763-1769
-
-
Muller, M.R.1
-
114
-
-
0037345749
-
Dendritic cells transfected with tumor RNA for the induction of antitumor CTL in colorectal cancer
-
Nencioni, A. et al. 2003. Dendritic cells transfected with tumor RNA for the induction of antitumor CTL in colorectal cancer. Cancer Gene Ther. 10: 209-214.
-
(2003)
Cancer Gene Ther
, vol.10
, pp. 209-214
-
-
Nencioni, A.1
-
115
-
-
0037305571
-
Induction of myeloma-specific cytotoxic T cells using dendritic cells transfected with tumor-derived RNA
-
Milazzo, C. et al. 2003. Induction of myeloma-specific cytotoxic T cells using dendritic cells transfected with tumor-derived RNA. Blood 101: 977-982.
-
(2003)
Blood
, vol.101
, pp. 977-982
-
-
Milazzo, C.1
-
116
-
-
2942559009
-
Cancer immunotherapy with mRNA-transfected dendritic cells
-
Gilboa, E. & J. Vieweg 2004. Cancer immunotherapy with mRNA-transfected dendritic cells. Immunol. Rev. 199: 251-263.
-
(2004)
Immunol. Rev
, vol.199
, pp. 251-263
-
-
Gilboa, E.1
Vieweg, J.2
-
117
-
-
0035870244
-
Human dendritic cells transfected with renal tumor RNA stimulate polyclonal T-cell responses against antigens expressed by primary and metastatic tumors
-
Heiser, A. et al. 2001. Human dendritic cells transfected with renal tumor RNA stimulate polyclonal T-cell responses against antigens expressed by primary and metastatic tumors. Cancer Res. 61: 3388-3393.
-
(2001)
Cancer Res
, vol.61
, pp. 3388-3393
-
-
Heiser, A.1
-
118
-
-
0034517560
-
Human dendritic cells transfected with either RNA or DNA encoding influenza matrix protein M1 differ in their ability to stimulate cytotoxic T lymphocytes
-
Strobel, I. et al. 2000. Human dendritic cells transfected with either RNA or DNA encoding influenza matrix protein M1 differ in their ability to stimulate cytotoxic T lymphocytes. Gene Ther. 7: 2028-2035.
-
(2000)
Gene Ther
, vol.7
, pp. 2028-2035
-
-
Strobel, I.1
-
119
-
-
0034670002
-
Induction of antitumor immunity by vaccination of dendritic cells transfected with MUC1 RNA
-
Koido, S. et al. 2000. Induction of antitumor immunity by vaccination of dendritic cells transfected with MUC1 RNA. J. Immunol. 165: 5713-5719.
-
(2000)
J. Immunol
, vol.165
, pp. 5713-5719
-
-
Koido, S.1
-
120
-
-
0036167308
-
Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors
-
Heiser, A. et al. 2002. Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors. J. Clin. Invest. 109: 409-417.
-
(2002)
J. Clin. Invest
, vol.109
, pp. 409-417
-
-
Heiser, A.1
-
121
-
-
73549125003
-
Immunologic activity and safety of autologous HIV RNA-electroporated dendritic cells in HIV-1 infected patients receiving antiretroviral therapy
-
Routy, J.P. et al. 2010. Immunologic activity and safety of autologous HIV RNA-electroporated dendritic cells in HIV-1 infected patients receiving antiretroviral therapy. Clin. Immunol. 134: 140-147.
-
(2010)
Clin. Immunol
, vol.134
, pp. 140-147
-
-
Routy, J.P.1
-
122
-
-
63849151352
-
Improving vaccines by targeting antigens to dendritic cells
-
Shortman, K., M.H. Lahoud & I. Caminschi 2009. Improving vaccines by targeting antigens to dendritic cells. Exp. Mol. Med. 41: 61-66.
-
(2009)
Exp. Mol. Med
, vol.41
, pp. 61-66
-
-
Shortman, K.1
Lahoud, M.H.2
Caminschi, I.3
-
123
-
-
33747362405
-
Targeting antigens to dendritic cells in vivo
-
Tacken, P.J., R. Torensma & C.G. Figdor 2006. Targeting antigens to dendritic cells in vivo. Immunobiology 211: 599-608.
-
(2006)
Immunobiology
, vol.211
, pp. 599-608
-
-
Tacken, P.J.1
Torensma, R.2
Figdor, C.G.3
-
124
-
-
41149108216
-
Enhancing the clinical activity of granulocyte-macrophage colony-stimulating factor-secreting tumor cell vaccines
-
Jinushi, M., F.S. Hodi & G. Dranoff 2008. Enhancing the clinical activity of granulocyte-macrophage colony-stimulating factor-secreting tumor cell vaccines. Immunol. Rev. 222: 287-298.
-
(2008)
Immunol. Rev
, vol.222
, pp. 287-298
-
-
Jinushi, M.1
Hodi, F.S.2
Dranoff, G.3
-
125
-
-
67650648512
-
Cytokine gene-mediated immunotherapy: current status and future perspectives
-
Jinushi, M. & H. Tahara 2009. Cytokine gene-mediated immunotherapy: current status and future perspectives. Cancer Sci. 100: 1389-1396.
-
(2009)
Cancer Sci
, vol.100
, pp. 1389-1396
-
-
Jinushi, M.1
Tahara, H.2
-
126
-
-
34447258415
-
Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine
-
Filipazzi, P. et al. 2007. Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. J. Clin. Oncol. 25: 2546-2553.
-
(2007)
J. Clin. Oncol
, vol.25
, pp. 2546-2553
-
-
Filipazzi, P.1
-
127
-
-
34248172324
-
Altered macrophage differentiation and immune dysfunction in tumor development
-
Sica, A. & V. Bronte 2007. Altered macrophage differentiation and immune dysfunction in tumor development. J. Clin. Invest. 117: 1155-1166.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 1155-1166
-
-
Sica, A.1
Bronte, V.2
-
128
-
-
79151486551
-
A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A phase II trial of safety, efficacy, and immune activation
-
Lutz, E. et al. 2011. A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A phase II trial of safety, efficacy, and immune activation. Ann. Surg. 253: 328-335.
-
(2011)
Ann. Surg
, vol.253
, pp. 328-335
-
-
Lutz, E.1
-
129
-
-
84862150896
-
Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer
-
Bayne, L.J. et al. 2012. Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer. Cancer Cell. 21: 822-835.
-
(2012)
Cancer Cell
, vol.21
, pp. 822-835
-
-
Bayne, L.J.1
-
130
-
-
59149106509
-
C-type lectins on dendritic cells: key modulators for the induction of immune responses
-
van Kooyk, Y. 2008. C-type lectins on dendritic cells: key modulators for the induction of immune responses. Biochem. Soc. Trans. 36: 1478-1481.
-
(2008)
Biochem. Soc. Trans
, vol.36
, pp. 1478-1481
-
-
van Kooyk, Y.1
-
131
-
-
54049145131
-
The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement
-
Caminschi, I. et al. 2008. The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement. Blood 112: 3264-3273.
-
(2008)
Blood
, vol.112
, pp. 3264-3273
-
-
Caminschi, I.1
-
132
-
-
33746864909
-
+ T cell responses through in vivo targeting of antigen to dendritic cell-associated C-type lectin-1
-
+ T cell responses through in vivo targeting of antigen to dendritic cell-associated C-type lectin-1. J. Immunol. 177: 2276-2284.
-
(2006)
J. Immunol
, vol.177
, pp. 2276-2284
-
-
Carter, R.W.1
-
133
-
-
33745823102
-
+ T cell responses through targeting of antigen to Dectin-2
-
+ T cell responses through targeting of antigen to Dectin-2. Cell Immunol. 239: 87-91.
-
(2006)
Cell Immunol
, vol.239
, pp. 87-91
-
-
Carter, R.W.1
-
134
-
-
33645087653
-
Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses
-
Boscardin, S.B. et al. 2006. Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. J. Exp. Med. 203: 599-606.
-
(2006)
J. Exp. Med
, vol.203
, pp. 599-606
-
-
Boscardin, S.B.1
-
135
-
-
84862777557
-
Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice
-
Wang, B. et al. 2012. Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice. Breast Cancer Res. 14: R39.
-
(2012)
Breast Cancer Res
, vol.14
-
-
Wang, B.1
-
136
-
-
78149432061
-
Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti-human DEC205 monoclonal antibody
-
Cheong, C. et al. 2010. Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti-human DEC205 monoclonal antibody. Blood 116: 3828-3838.
-
(2010)
Blood
, vol.116
, pp. 3828-3838
-
-
Cheong, C.1
-
137
-
-
79952294318
-
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
-
Idoyaga, J. et al. 2011. Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A. Proc. Natl. Acad. Sci. US A 108: 2384-2389.
-
(2011)
Proc. Natl. Acad. Sci. US A
, vol.108
, pp. 2384-2389
-
-
Idoyaga, J.1
-
138
-
-
23744481998
-
Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody
-
Tacken, P.J. et al. 2005. Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody. Blood 106: 1278-1285.
-
(2005)
Blood
, vol.106
, pp. 1278-1285
-
-
Tacken, P.J.1
-
139
-
-
10744226740
-
Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs anti-melanoma T cell responses via multiple HLA molecules
-
Ramakrishna, V. et al. 2004. Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs anti-melanoma T cell responses via multiple HLA molecules. J. Immunol. 172: 2845-2852.
-
(2004)
J. Immunol
, vol.172
, pp. 2845-2852
-
-
Ramakrishna, V.1
-
140
-
-
84855931820
-
Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity
-
Trumpfheller, C. et al. 2012. Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity. J. Intern. Med. 271: 183-192.
-
(2012)
J. Intern. Med
, vol.271
, pp. 183-192
-
-
Trumpfheller, C.1
-
141
-
-
65249088470
-
Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients
-
Verdijk, P. et al. 2009. Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients. Clin. Cancer Res. 15: 2531-2540.
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 2531-2540
-
-
Verdijk, P.1
-
142
-
-
84864196063
-
Clinical trial of the intratumoral administration of labeled DC combined with systemic chemotherapy for esophageal cancer
-
Fujiwara, S. et al. 2012. Clinical trial of the intratumoral administration of labeled DC combined with systemic chemotherapy for esophageal cancer. J. Immunother. 35: 513-521.
-
(2012)
J. Immunother
, vol.35
, pp. 513-521
-
-
Fujiwara, S.1
-
143
-
-
80052439234
-
Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients
-
Lesterhuis, W.J. et al. 2011. Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients. Clin. Cancer Res. 17: 5725-5735.
-
(2011)
Clin. Cancer Res
, vol.17
, pp. 5725-5735
-
-
Lesterhuis, W.J.1
-
144
-
-
84875183933
-
Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells
-
Aarntzen, E.H. et al. 2013. Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells. Clin. Cancer Res. 19: 1525-1533
-
(2013)
Clin. Cancer Res
, vol.19
, pp. 1525-1533
-
-
Aarntzen, E.H.1
-
145
-
-
77955261234
-
+ T cell priming by dendritic cell vaccines requires antigen transfer to endogenous antigen presenting cells
-
+ T cell priming by dendritic cell vaccines requires antigen transfer to endogenous antigen presenting cells. PLoS One 5: e11144.
-
(2010)
PLoS One
, vol.5
-
-
Yewdall, A.W.1
-
146
-
-
33645325115
-
Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG
-
Schadendorf, D. et al. 2006. Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG. Ann. Oncol. 17: 563-570.
-
(2006)
Ann. Oncol
, vol.17
, pp. 563-570
-
-
Schadendorf, D.1
-
147
-
-
68549135290
-
Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
-
Higano, C.S. et al. 2009. Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer 115: 3670-3679.
-
(2009)
Cancer
, vol.115
, pp. 3670-3679
-
-
Higano, C.S.1
-
148
-
-
56149106010
-
Dendritic cells dysfunction in tumour environment
-
Bennaceur, K. et al. 2008. Dendritic cells dysfunction in tumour environment. Cancer Lett. 272: 186-196.
-
(2008)
Cancer Lett
, vol.272
, pp. 186-196
-
-
Bennaceur, K.1
-
149
-
-
34848907785
-
Role of altered expression of HLA class I molecules in cancer progression
-
Aptsiauri, N. et al. 2007. Role of altered expression of HLA class I molecules in cancer progression. Adv. Exp. Med. Biol. 601: 123-131.
-
(2007)
Adv. Exp. Med. Biol
, vol.601
, pp. 123-131
-
-
Aptsiauri, N.1
-
150
-
-
65549138993
-
Suppressive influences in the immune response to cancer
-
Bronte, V. & S. Mocellin 2009. Suppressive influences in the immune response to cancer. J. Immunother. 32: 1-11.
-
(2009)
J. Immunother
, vol.32
, pp. 1-11
-
-
Bronte, V.1
Mocellin, S.2
-
151
-
-
33745813122
-
Defective human leukocyte antigen class I-associated antigen presentation caused by a novel beta2-microglobulin loss-of-function in melanoma cells
-
Chang, C.C. et al. 2006. Defective human leukocyte antigen class I-associated antigen presentation caused by a novel beta2-microglobulin loss-of-function in melanoma cells. J. Biol. Chem. 281: 18763-18773.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 18763-18773
-
-
Chang, C.C.1
-
152
-
-
68149155982
-
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies
-
Peggs, K.S. et al. 2009. Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies. J. Exp. Med. 206: 1717-1725.
-
(2009)
J. Exp. Med
, vol.206
, pp. 1717-1725
-
-
Peggs, K.S.1
-
153
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy. Nature reviews
-
Pardoll, D.M. 2012. The blockade of immune checkpoints in cancer immunotherapy. Nature reviews. Cancer 12: 252-264.
-
(2012)
Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
154
-
-
0037126021
-
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
-
Iwai, Y. et al. 2002. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc. Natl. Acad. Sci. USA 99: 12293-12297.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12293-12297
-
-
Iwai, Y.1
-
155
-
-
0141953992
-
B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma
-
Strome, S.E. et al. 2003. B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma. Cancer Res. 63: 6501-6505.
-
(2003)
Cancer Res
, vol.63
, pp. 6501-6505
-
-
Strome, S.E.1
-
156
-
-
33745197352
-
Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro
-
Blank, C. et al. 2006. Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro. Int. J. Cancer 119: 317-327.
-
(2006)
Int. J. Cancer
, vol.119
, pp. 317-327
-
-
Blank, C.1
-
157
-
-
49649114804
-
Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
-
Berger, R. et al. 2008. Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin. Cancer Res. 14: 3044-3051.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 3044-3051
-
-
Berger, R.1
-
158
-
-
77954899030
-
Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer, J.R. et al. 2010. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J. Clin. Oncol. 28: 3167-3175.
-
(2010)
J. Clin. Oncol
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
-
159
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian, S.L. et al. 2012. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366: 2443-2454.
-
(2012)
N. Engl. J. Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
-
160
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer, J.R. et al. 2012. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N. Engl. J. Med. 366: 2455-2465.
-
(2012)
N. Engl. J. Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
-
161
-
-
58149483422
-
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
-
Yuan, J. et al. 2008. CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit. Proc. Natl. Acad. Sci. USA 105: 20410-20415.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 20410-20415
-
-
Yuan, J.1
-
162
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi, F.S. et al. 2010. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363: 711-723.
-
(2010)
N. Engl. J. Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
-
163
-
-
36849035139
-
Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): a novel strategy for the treatment of melanoma and other malignancies
-
O'Day, S.J., O. Hamid & W.J. Urba 2007. Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): a novel strategy for the treatment of melanoma and other malignancies. Cancer 110: 2614-2627.
-
(2007)
Cancer
, vol.110
, pp. 2614-2627
-
-
O'Day, S.J.1
Hamid, O.2
Urba, W.J.3
-
164
-
-
65349153714
-
Immune regulation by 4-1BB and 4-1BBL: complexities and challenges
-
Wang, C. et al. 2009. Immune regulation by 4-1BB and 4-1BBL: complexities and challenges. Immunol. Rev. 229: 192-215.
-
(2009)
Immunol. Rev
, vol.229
, pp. 192-215
-
-
Wang, C.1
-
166
-
-
70349243743
-
In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb
-
Murillo, O. et al. 2009. In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb. Eur. J. Immunol. 39: 2424-2436.
-
(2009)
Eur. J. Immunol
, vol.39
, pp. 2424-2436
-
-
Murillo, O.1
-
167
-
-
33746924449
-
Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity
-
Kocak, E. et al. 2006. Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity. Cancer Res. 66: 7276-7284.
-
(2006)
Cancer Res
, vol.66
, pp. 7276-7284
-
-
Kocak, E.1
-
168
-
-
84865316603
-
Immunomodulating antibodies in the treatment of metastatic melanoma: the experience with anti-CTLA-4, anti-CD137, and anti-PD1
-
Simeone, E. & P.A. Ascierto 2012. Immunomodulating antibodies in the treatment of metastatic melanoma: the experience with anti-CTLA-4, anti-CD137, and anti-PD1. J. Immunotoxicol. 9: 241-247.
-
(2012)
J. Immunotoxicol
, vol.9
, pp. 241-247
-
-
Simeone, E.1
Ascierto, P.A.2
-
169
-
-
65349149089
-
Molecular mechanism and function of CD40/CD40L engagement in the immune system
-
Elgueta, R. et al. 2009. Molecular mechanism and function of CD40/CD40L engagement in the immune system. Immunol. Rev. 229: 152-172.
-
(2009)
Immunol. Rev
, vol.229
, pp. 152-172
-
-
Elgueta, R.1
-
170
-
-
84874845333
-
Agonistic CD40 antibodies and cancer therapy
-
Vonderheide, R.H. & M.J. Glennie 2013. Agonistic CD40 antibodies and cancer therapy. Clin. Cancer Res. 19: 1035-1043.
-
(2013)
Clin. Cancer Res
, vol.19
, pp. 1035-1043
-
-
Vonderheide, R.H.1
Glennie, M.J.2
-
171
-
-
79953154967
-
CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans
-
Beatty, G.L. et al. 2011. CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans. Science 331: 1612-1616.
-
(2011)
Science
, vol.331
, pp. 1612-1616
-
-
Beatty, G.L.1
-
172
-
-
21244447927
-
Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help
-
Kutzler, M.A. et al. 2005. Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help. J. Immunol. 175: 112-123.
-
(2005)
J. Immunol
, vol.175
, pp. 112-123
-
-
Kutzler, M.A.1
-
174
-
-
33644816267
-
+ T cells for use in adoptive immunotherapy of established tumors
-
+ T cells for use in adoptive immunotherapy of established tumors. Nat. Med. 12: 335-341.
-
(2006)
Nat. Med
, vol.12
, pp. 335-341
-
-
Teague, R.M.1
-
175
-
-
84855804372
-
Interleukin-15 biology and its therapeutic implications in cancer
-
Steel, J.C., T.A. Waldmann & J.C. Morris 2012. Interleukin-15 biology and its therapeutic implications in cancer. Trends Pharmacol. Sci. 33: 35-41.
-
(2012)
Trends Pharmacol. Sci
, vol.33
, pp. 35-41
-
-
Steel, J.C.1
Waldmann, T.A.2
Morris, J.C.3
-
176
-
-
77953101577
-
Combination of IL-21 and IL-15 enhances tumour-specific cytotoxicity and cytokine production of TCR-transduced primary T cells
-
Pouw, N. et al. 2010. Combination of IL-21 and IL-15 enhances tumour-specific cytotoxicity and cytokine production of TCR-transduced primary T cells. Cancer Immunol. Immunother. 59: 921-931.
-
(2010)
Cancer Immunol. Immunother
, vol.59
, pp. 921-931
-
-
Pouw, N.1
-
177
-
-
79957716455
-
Interleukin 15 as a promising candidate for tumor immunotherapy
-
Jakobisiak, M., J. Golab & W. Lasek 2011. Interleukin 15 as a promising candidate for tumor immunotherapy. Cytok. Growth Factor Rev. 22: 99-108.
-
(2011)
Cytok. Growth Factor Rev
, vol.22
, pp. 99-108
-
-
Jakobisiak, M.1
Golab, J.2
Lasek, W.3
-
178
-
-
0034332403
-
Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
-
Schluns, K.S. et al. 2000. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat. Immunol. 1: 426-432.
-
(2000)
Nat. Immunol
, vol.1
, pp. 426-432
-
-
Schluns, K.S.1
-
180
-
-
56449097201
-
Type 2 Bias of T cells expanded from the blood of melanoma patients switched to type 1 by IL-12p70 mRNA-transfected dendritic cells
-
Minkis, K. et al. 2008. Type 2 Bias of T cells expanded from the blood of melanoma patients switched to type 1 by IL-12p70 mRNA-transfected dendritic cells. Cancer Res. 68: 9441-9450.
-
(2008)
Cancer Res
, vol.68
, pp. 9441-9450
-
-
Minkis, K.1
-
181
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri, G. 2003. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3: 133-146.
-
(2003)
Nat. Rev. Immunol
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
182
-
-
33847764924
-
Targeting HER-2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion
-
Czerniecki, B.J. et al. 2007. Targeting HER-2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion. Cancer Res. 67: 1842-1852.
-
(2007)
Cancer Res
, vol.67
, pp. 1842-1852
-
-
Czerniecki, B.J.1
-
183
-
-
79953318400
-
A phase 1 study of AS1409, a novel antibody-cytokine fusion protein, in patients with malignant melanoma or renal cell carcinoma
-
Rudman, S.M. et al. 2011. A phase 1 study of AS1409, a novel antibody-cytokine fusion protein, in patients with malignant melanoma or renal cell carcinoma. Clin. Cancer Res. 17: 1998-2005.
-
(2011)
Clin. Cancer Res
, vol.17
, pp. 1998-2005
-
-
Rudman, S.M.1
-
184
-
-
0037136303
-
Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody
-
Vicari, A.P. et al. 2002. Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody. J. Exp. Med. 196: 541-549.
-
(2002)
J. Exp. Med
, vol.196
, pp. 541-549
-
-
Vicari, A.P.1
-
185
-
-
67449136111
-
Inhibition of transforming growth factor-beta-mediated immunosuppression in tumor-draining lymph nodes augments antitumor responses by various immunologic cell types
-
Fujita, T. et al. 2009. Inhibition of transforming growth factor-beta-mediated immunosuppression in tumor-draining lymph nodes augments antitumor responses by various immunologic cell types. Cancer Res. 69: 5142-5150.
-
(2009)
Cancer Res
, vol.69
, pp. 5142-5150
-
-
Fujita, T.1
-
186
-
-
60849084473
-
Prolonged survival of dendritic cell-vaccinated melanoma patients correlates with tumor-specific delayed type IV hypersensitivity response and reduction of tumor growth factor beta-expressing T cells
-
Lopez, M.N. et al. 2009. Prolonged survival of dendritic cell-vaccinated melanoma patients correlates with tumor-specific delayed type IV hypersensitivity response and reduction of tumor growth factor beta-expressing T cells. J. Clin. Oncol. 27: 945-952.
-
(2009)
J. Clin. Oncol
, vol.27
, pp. 945-952
-
-
Lopez, M.N.1
-
187
-
-
14644390867
-
+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
-
+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. J. Clin. Invest. 115: 739-746.
-
(2005)
J. Clin. Invest
, vol.115
, pp. 739-746
-
-
Speiser, D.E.1
-
188
-
-
67650445798
-
+ Th1 immunity with poly IC as adjuvant
-
+ Th1 immunity with poly IC as adjuvant. J. Exp. Med. 206: 1589-1602.
-
(2009)
J. Exp. Med
, vol.206
, pp. 1589-1602
-
-
Longhi, M.P.1
-
189
-
-
33745945647
-
Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo
-
Warger, T. et al. 2006. Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo. Blood 108: 544-550.
-
(2006)
Blood
, vol.108
, pp. 544-550
-
-
Warger, T.1
-
190
-
-
39249083535
-
Vaccine adjuvant systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers
-
Vandepapeliere, P. et al. 2008. Vaccine adjuvant systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers. Vaccine 26: 1375-1386.
-
(2008)
Vaccine
, vol.26
, pp. 1375-1386
-
-
Vandepapeliere, P.1
-
191
-
-
33644521564
-
Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens
-
Baumgaertner, P. et al. 2006. Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens. Cancer Res. 66: 1912-1916.
-
(2006)
Cancer Res
, vol.66
, pp. 1912-1916
-
-
Baumgaertner, P.1
-
192
-
-
52049088540
-
Safety and immunogenicity study of NY-ESO-1b peptide and montanide ISA-51 vaccination of patients with epithelial ovarian cancer in high-risk first remission
-
Diefenbach, C.S. et al. 2008. Safety and immunogenicity study of NY-ESO-1b peptide and montanide ISA-51 vaccination of patients with epithelial ovarian cancer in high-risk first remission. Clin. Cancer Res. 14: 2740-2748.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 2740-2748
-
-
Diefenbach, C.S.1
-
193
-
-
59849116262
-
Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8+ T cells in melanoma patients
-
Fourcade, J. et al. 2008. Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8+ T cells in melanoma patients. J. Immunother. 31: 781-791.
-
(2008)
J. Immunother
, vol.31
, pp. 781-791
-
-
Fourcade, J.1
-
194
-
-
63849276117
-
Harnessing human CD1d restricted T cells for tumor immunity: progress and challenges
-
Dhodapkar, M.V. 2009. Harnessing human CD1d restricted T cells for tumor immunity: progress and challenges. Front. Biosci. 14: 796-807.
-
(2009)
Front. Biosci
, vol.14
, pp. 796-807
-
-
Dhodapkar, M.V.1
-
195
-
-
20844451391
-
Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha-galactosyl-ceramide loaded mature dendritic cells in cancer patients
-
Chang, D.H. et al. 2005. Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha-galactosyl-ceramide loaded mature dendritic cells in cancer patients. J. Exp. Med. 201: 1503-1517.
-
(2005)
J. Exp. Med
, vol.201
, pp. 1503-1517
-
-
Chang, D.H.1
-
196
-
-
20044364936
-
Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas
-
Marshall, J.L. et al. 2005. Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas. J. Clin. Oncol. 23: 720-731.
-
(2005)
J. Clin. Oncol
, vol.23
, pp. 720-731
-
-
Marshall, J.L.1
-
197
-
-
0034551730
-
Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses
-
Marshall, J.L. et al. 2000. Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses. J. Clin. Oncol. 18: 3964-3973.
-
(2000)
J. Clin. Oncol
, vol.18
, pp. 3964-3973
-
-
Marshall, J.L.1
-
198
-
-
68349083269
-
Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations
-
Kaneno, R. et al. 2009. Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations. J. Transl. Med. 7: 58.
-
(2009)
J. Transl. Med
, vol.7
, pp. 58
-
-
Kaneno, R.1
-
199
-
-
68349123372
-
Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by dendritic cells via an IL-12-dependent mechanism
-
Shurin, G.V. et al. 2009. Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by dendritic cells via an IL-12-dependent mechanism. J. Immunol. 183: 137-144.
-
(2009)
J. Immunol
, vol.183
, pp. 137-144
-
-
Shurin, G.V.1
-
200
-
-
1442284594
-
Drug-induced increase of carcinoembryonic antigen expression in cancer cells
-
Aquino, A. et al. 2004. Drug-induced increase of carcinoembryonic antigen expression in cancer cells. Pharmacol. Res. 49: 383-396.
-
(2004)
Pharmacol. Res
, vol.49
, pp. 383-396
-
-
Aquino, A.1
-
201
-
-
0037457485
-
Treatment of colon and breast carcinoma cells with 5-fluorouracil enhances expression of carcinoembryonic antigen and susceptibility to HLA-A(*)02.01 restricted, CEA-peptide-specific cytotoxic T cells in vitro
-
Correale, P. et al. 2003. Treatment of colon and breast carcinoma cells with 5-fluorouracil enhances expression of carcinoembryonic antigen and susceptibility to HLA-A(*)02.01 restricted, CEA-peptide-specific cytotoxic T cells in vitro. Int. J. Cancer 104: 437-445.
-
(2003)
Int. J. Cancer
, vol.104
, pp. 437-445
-
-
Correale, P.1
-
202
-
-
84864518950
-
Recent advances in intravital imaging of dynamic biological systems
-
Kikuta, J. & M. Ishii 2012. Recent advances in intravital imaging of dynamic biological systems. J. Pharmacol. Sci. 119: 193-197.
-
(2012)
J. Pharmacol. Sci
, vol.119
, pp. 193-197
-
-
Kikuta, J.1
Ishii, M.2
-
203
-
-
11144283687
-
Therapeutic dendritic-cell vaccine for chronic HIV-1 infection
-
Lu, W. et al. 2004. Therapeutic dendritic-cell vaccine for chronic HIV-1 infection. Nat. Med. 10: 1359-1365.
-
(2004)
Nat. Med
, vol.10
, pp. 1359-1365
-
-
Lu, W.1
-
204
-
-
84872037286
-
A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication
-
Garcia, F. et al. 2013. A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication. Sci. Transl. Med. 5: 166ra162.
-
(2013)
Sci. Transl. Med
, vol.5
-
-
Garcia, F.1
|